2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. Vocacapsaicin hydrochloride

Vocacapsaicin hydrochloride  (Synonyms: CA-008 hydrochloride)

Cat. No.: HY-137459A Purity: 95.66%
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Vocacapsaicin (CA-008) hydrochloride, a proagent of Capsaicin, is a first-in-class non-opioid TRPV1 agonist. Vocacapsaicin hydrochloride can provide meaningful and long-lasting pain relief.

For research use only. We do not sell to patients.

Vocacapsaicin hydrochloride

Vocacapsaicin hydrochloride Chemical Structure

CAS No. : 1931116-92-5

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
1 mg In-stock
5 mg In-stock
10 mg In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Vocacapsaicin hydrochloride:

Vocacapsaicin hydrochloride Related Antibodies

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  • Biological Activity

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Description

Vocacapsaicin (CA-008) hydrochloride, a proagent of Capsaicin, is a first-in-class non-opioid TRPV1 agonist. Vocacapsaicin hydrochloride can provide meaningful and long-lasting pain relief[1].

Clinical Trial
Molecular Weight

496.08

Formula

C26H42ClN3O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[H]Cl.O=C(N(CCCC1)C1CNC)OC(C=CC(CNC(CCCC/C=C/C(C)C)=O)=C2)=C2OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (201.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0158 mL 10.0790 mL 20.1580 mL
5 mM 0.4032 mL 2.0158 mL 4.0316 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0158 mL 10.0790 mL 20.1580 mL 50.3951 mL
5 mM 0.4032 mL 2.0158 mL 4.0316 mL 10.0790 mL
10 mM 0.2016 mL 1.0079 mL 2.0158 mL 5.0395 mL
15 mM 0.1344 mL 0.6719 mL 1.3439 mL 3.3597 mL
20 mM 0.1008 mL 0.5040 mL 1.0079 mL 2.5198 mL
25 mM 0.0806 mL 0.4032 mL 0.8063 mL 2.0158 mL
30 mM 0.0672 mL 0.3360 mL 0.6719 mL 1.6798 mL
40 mM 0.0504 mL 0.2520 mL 0.5040 mL 1.2599 mL
50 mM 0.0403 mL 0.2016 mL 0.4032 mL 1.0079 mL
60 mM 0.0336 mL 0.1680 mL 0.3360 mL 0.8399 mL
80 mM 0.0252 mL 0.1260 mL 0.2520 mL 0.6299 mL
100 mM 0.0202 mL 0.1008 mL 0.2016 mL 0.5040 mL
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Vocacapsaicin hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vocacapsaicin1931116-92-5CA-008CA008CA 008TRP ChannelTransient receptor potential channelsnon-opioidlonglastingpainreliefprodurgInhibitorinhibitorinhibit

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