2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. GRC-6211

GRC-6211 is an orally active and selective TRPV1 antagonist. GRC-6211 exhibits anti-inflammation effect.

For research use only. We do not sell to patients.

GRC-6211

GRC-6211 Chemical Structure

CAS No. : 1166398-35-1

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GRC-6211 Related Antibodies

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Description

GRC-6211 is an orally active and selective TRPV1 antagonist. GRC-6211 exhibits anti-inflammation effect[1].

IC50 & Target[1]

TRPV1

 

In Vivo

GRC-6211 (0.001-1 mg/kg, through a duodenal catheter) decreases bladder overactivity and noxious bladder input in cystitis rats models[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

359.42

Formula

C22H21N3O2
CAS No.
SMILES

O=C(NC1=CC=CC2=C1C=CN=C2)N[C@@H]3CC4(CCC4)OC5=CC=CC=C53
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GRC-6211 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GRC-62111166398-35-1GRC6211GRC 6211TRP ChannelTransient receptor potential channelsTRPV1anti-inflammationcystitisInhibitorinhibitorinhibit

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