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nucleic acids

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254

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58

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38

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10

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29

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-170333

    Biochemical Assay Reagents Cancer
    Lipid A-11 (A-11) can be used to synthesize lipid-like nanoparticles (LNPs) for delivery of nucleic acids .
    Lipid A-11
  • HY-112754A
    DOTAP chloride
    5+ Cited Publications

    1,2-Dioleoyl-3-trimethylammonium-propane chloride

    Liposome Cancer
    DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .
    DOTAP chloride
  • HY-D0184
    2'-Deoxycytidine
    5+ Cited Publications

    Deoxycytidine; Cytosine deoxyriboside; Deoxyribose cytidine

    Endogenous Metabolite Cancer
    2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer .
    2'-Deoxycytidine
  • HY-D0941

    Fluorescent Dye Others
    5-Carboxytetramethylrhodamine can be used as a fluorescent probe of nucleic acids and proteins. 5-Carboxytetramethylrhodamine displays excitation maxima of 558 nm and an emission maximum of 586 nm .
    5-Carboxytetramethylrhodamine
  • HY-154804

    Liposome Others
    DLin-M-C4-DMA (Compound MC4) is a cationic lipid. DLin-M-C4-DMA can be used for delivery of nucleic acids .
    DLin-M-C4-DMA
  • HY-46317

    DNA/RNA Synthesis Others
    DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding .
    DMT-5Me-dC(Bz)-CE Phosphoramidite
  • HY-153125

    Liposome Others
    DLRIE is a cationic lipid that can be used for the synthesis of liposome GAP-DLRIE. GAP-DLRIE can be used to enhance the delivery and expression of plasmid DNA. DLRIE can be used for delivery of nucleic acids .
    DLRIE
  • HY-147320

    DNA/RNA Synthesis Others
    3'-DMTr-dG(dmf) is a guanosine derivative used in the synthesis of nucleic acids .
    3'-DMTr-dG(dmf)
  • HY-165427

    Liposome Cancer
    Lipid 11 (Compound Lipid 1) is a cationic lipid for nucleic acid delivery. Lipid 11 forms lipid nanoparticles (LNPs) through electrostatic binding with nucleic acids (such as ceDNA). Lipid 11 forms complexes with negatively charged nucleic acids via cationic amine groups, which can be endocytosed by cells to release nucleic acids for activity. Lipid 11 is promising for research of gene therapy drug delivery systems .
    Lipid 11
  • HY-P3150

    Ser/Thr Protease Others
    Recombinant Proteinase K is a serine protease that cleaves the carboxy-terminated peptide bonds of aliphatic and aromatic amino acids. Recombinant Proteinase K can be used to digest proteins and remove contamination from nucleic acid preparations .
    Recombinant Proteinase K
  • HY-D0115

    DNA Stain Others
    7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is a blue fluorescent dye for labeling proteins and nucleic acids .
    7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester
  • HY-N2625

    Apoptosis Cancer
    Harmalol is a β-carbazine alkaloid with anticancer activity. Harmalol binds and interacts with several natural and synthetic nucleic acids of different motifs, including DNA and RNA. In addition, harmalol has an apoptosis-inducing effect on human hepatoma cells in vitro .
    Harmalol
  • HY-Y1055
    Guanine
    3 Publications Verification

    DNA/RNA Synthesis Endogenous Metabolite Neurological Disease Cancer
    Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects .
    Guanine
  • HY-Y1055R

    Reference Standards DNA/RNA Synthesis Endogenous Metabolite Cancer
    Guanine (Standard) is the analytical standard of Guanine. This product is intended for research and analytical applications. Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool .
    Guanine (Standard)
  • HY-151778

    ADC Linker Others
    Fmoc-Abg(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-Abg(N3)-OH has the potential to synthesize peptide nucleic acids (PNA) and peptoids. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-Abg(N3)-OH
  • HY-106991A

    S-303 dihydrochloride

    HIV Bacterial Infection
    Amustaline (S-303) dihydrochloride, a nucleic acid-targeted alkylator, is an efficient pathogen inactivation agent for blood components containing red blood cells. Amustaline dihydrochloride has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products) .
    Amustaline dihydrochloride
  • HY-126327

    Histone Methyltransferase Cancer
    UNC4976 is a positive allosteric modulator (PAM) peptidomimetic of CBX7 chromodomain binding to nucleic acids. UNC4976 simultaneously antagonizes H3K27me3-specific recruitment of CBX7 to target genes while increasing non-specific binding to DNA and RNA .
    UNC4976
  • HY-126327A

    Histone Methyltransferase Cancer
    UNC4976 TFA is a positive allosteric modulator (PAM) peptidomimetic of CBX7 chromodomain binding to nucleic acids. UNC4976 TFA simultaneously antagonizes H3K27me3-specific recruitment of CBX7 to target genes while increasing non-specific binding to DNA and RNA .
    UNC4976 TFA
  • HY-106991AR

    HIV Bacterial Infection
    Amustaline (dihydrochloride) (Standard) is the analytical standard of Amustaline (dihydrochloride). This product is intended for research and analytical applications. Amustaline (S-303) dihydrochloride, a nucleic acid-targeted alkylator, is an efficient pathogen inactivation agent for blood components containing red blood cells. Amustaline dihydrochloride has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products) .
    Amustaline dihydrochloride (Standard)
  • HY-155995

    MK-905

    Biochemical Assay Reagents Cancer
    Pro-905 is a phosphite peptide with antitumor activity. Pro-905 delivers the active nucleotide antimetabolite thioguanosine monophosphate (TGMP) to the tumor. Pro-905 effectively prevents incorporation of purine salvage substrates into nucleic acids and inhibits colony formation in human malignant peripheral nerve sheath tumors (MPNST) cells. Pro-905 inhibits purine salvage incorporation to nucleic acids and prevents cell growth. Pro-905 inhibits the growth of MPNST and enhances the anti-tumor efficacy of JHU395 (HY-124778) .
    PRO-905
  • HY-D0150
    Thiazole Orange
    1 Publications Verification

    Fluorescent Dye Others
    Thiazole Orange is an asymmetric anthocyanin dye that can be coupled with oligonucleotides (ONs) to prepare fluorescent hybridization probes. Thiazole Orange has been widely used in biomolecular detection and staining of DNA/ RNA in gels and can be used for reticulocyte analysis. Thiazole orange generates a significant fluorescence enhancement and high quantum yield when it binds with nucleic acids, especially RNA. Thiazole orange can permeate living cell membranes. Thiazole orange can use UV light for detection, but can also be detected with blue light. The excitation and emission of Thiazole orange are λex = 510 nm (488 nm and 470 nm also show strong excitation) and λem = 527 nm, respectively .
    Thiazole Orange
  • HY-125818C

    Cytidine triphosphate disodium hydrate; 5'-CTP disodium hydrate

    DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite Infection Cancer
    Cytidine 5′-triphosphate is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
    Cytidine-5'-triphosphate disodium hydrate
  • HY-125818
    Cytidine-5'-triphosphate
    2 Publications Verification

    Cytidine triphosphate; 5'-CTP

    DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite Metabolic Disease
    Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
    Cytidine-5'-triphosphate
  • HY-125818R

    Cytidine triphosphate (Standard); 5'-CTP (Standard)

    DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite Others
    Cytidine-5'-triphosphate (Standard) is the analytical standard of Cytidine-5'-triphosphate. This product is intended for research and analytical applications. Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
    Cytidine-5'-triphosphate (Standard)
  • HY-D1045

    DABCYL; Para-methyl red

    Fluorescent Dye Others
    Dabcyl acid (Dabcyl) is a nonfluorescent chromophore and a quencher. Dabcyl acid can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .
    Dabcyl acid
  • HY-D1045A

    DABCYL sodium; Para-methyl red sodium

    Fluorescent Dye Others
    Dabcyl acid sodium (DABCYL sodium) is a nonfluorescent chromophore and a quencher. Dabcyl acid sodium can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .
    Dabcyl acid sodium
  • HY-142996

    Liposome Cancer
    BGTC is a non-amino acid cationic lipid. BGTC can be used for delivery of nucleic acids .
    BGTC
  • HY-W006103

    DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Others
    I-bu-rG Phosphoramidite is a phosphinamide monomer which can be used in the synthesis of nucleotides and nucleic acids.
    I-bu-rG Phosphoramidite
  • HY-W093086

    DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Others
    DMT-2'-F-Bz-dA can be used in the synthesis of nucleotides and nucleic acids.
    DMT-2'-F-Bz-dA
  • HY-125818S3

    Cytidine triphosphate-13C9 dilithium; 5'-CTP-13C9 dilithium

    Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite Infection Cancer
    Cytidine-5'-triphosphate- 13C9 (Cytidine triphosphate- 13C9 dilithium; 5'-CTP- 13C9) dilithium is 13C-labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.
    Cytidine-5'-triphosphate-13C9 dilithium
  • HY-125818S6

    Cytidine triphosphate-15N3 dilithium; 5'-CTP-15N3 dilithium

    Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite Infection Cancer
    Cytidine-5'-triphosphate- 15N3 (Cytidine triphosphate- 15N3 dilithium; 5'-CTP- 15N3) dilithium is 15N labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.
    Cytidine-5'-triphosphate-15N3 dilithium
  • HY-125818S4

    Cytidine triphosphate-d14 dilithium; 5'-CTP-d14 dilithium

    Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite Infection Cancer
    Cytidine-5'-triphosphate-d14 (Cytidine triphosphate-d14 dilithium; 5'-CTP-d14) dilithium is deuterium labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.
    Cytidine-5'-triphosphate-d14 dilithium
  • HY-66021
    6-FAM
    1 Publications Verification

    6-Carboxyfluorescein

    Fluorescent Dye Others
    6-FAM (6-Carboxyfluorescein) is an isomer of carboxyfluorescein and is mainly used for sequencing and labeling of nucleic acids.
    6-FAM
  • HY-148389

    Sialylglycoasparaginate

    Biochemical Assay Reagents Others
    Disialo-Asn is a N-Glycan and sialate glycopeptide. Disialo-Asn can be used for modify nucleic acids .
    Disialo-Asn
  • HY-138287

    Biochemical Assay Reagents Others
    4'-Aminomethyl-4,5',8-trimethylpsoralen is a photoreactive agent for crosslinking nucleic acids .
    4'-Aminomethyl-4,5',8-trimethylpsoralen
  • HY-W881219

    Drug Intermediate Others
    N6-Bz-A-(S)-GNA phosphoramidite is an important intermediate for the synthesis of nucleic acids and their analogs .
    N6-Bz-A-(S)-GNA phosphoramidite
  • HY-W881463

    Drug Intermediate Others
    N4-Ac-C-(S)-GNA phosphoramidite is an important intermediate for the synthesis of nucleic acids and their analogs .
    N4-Ac-C-(S)-GNA phosphoramidite
  • HY-W675848

    Drug Intermediate Others
    N4-Bz-C-(S)-GNA phosphoramidite is an important intermediate for the synthesis of nucleic acids and their analogs .
    N4-Bz-C-(S)-GNA phosphoramidite
  • HY-125818S2

    Cytidine triphosphate-13C,d1 dilithium; 5'-CTP-13C,d1 dilithium

    Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite Infection Cancer
    Cytidine-5'-triphosphate- 13C,d1 (Cytidine triphosphate- 13C,d1 dilithium; 5'-CTP- 13C,d1) dilithium is deuterium and 13C-labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.
    Cytidine-5'-triphosphate-13C,d1 dilithium
  • HY-119853

    NSC-17262

    Drug Derivative Infection
    Bayer A 139 is an ethylene-menaquinone that inactivates fowl plaque virus activity. Bayer A 139 can react with nucleic acids at pH ≦ 7 .
    Bayer A 139
  • HY-125818S5

    Cytidine triphosphate-15N3,d14 dilithium; 5'-CTP-15N3,d14 dilithium

    Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite Infection Cancer
    Cytidine-5'-triphosphate- 15N3,d14 (Cytidine triphosphate- 15N3,d14 dilithium; 5'-CTP- 15N3,d14) dilithium is deuterium and 15N labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.
    Cytidine-5'-triphosphate-15N3,d14 dilithium
  • HY-59354

    DNA/RNA Synthesis Cancer
    Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins .
    Maleic hydrazide
  • HY-135413

    Sulfo-Cyanine5 NHS ester

    DNA Stain Inflammation/Immunology Cancer
    MeCY5-NHS estera is a reactive dye. MeCY5-NHS estera can be used for the labeling of proteins and nucleic acids.
    MeCY5-NHS ester
  • HY-D1723
    EthD-III
    1 Publications Verification

    DNA Stain Others
    EthD-III is a nucleic acid probe. EthD-III is a red fluorescent stain that can be used to detect dead cells. EthD-III enters cells with damaged membranes and binds to nucleic acids, resulting in bright red fluorescence in dead cells (Ex/Em=530/645 nm) .
    EthD-III
  • HY-W540122

    Biochemical Assay Reagents Others
    Fmoc-PNA-C(Bhoc)-OH is a peptide nucleic acid monomers, and can be used in the synthesis of peptide nucleic acid compounds .
    Fmoc-PNA-C(Bhoc)-OH
  • HY-W320685

    Drug Intermediate Others
    (S)-N-Boc-L-homoserine ethyl ester is a synthetic intermediate in the synthesis of unsaturated caprolactams and monomer units for oxy-peptide nucleic acids from the starting material L-homoserine.
    (S)-N-Boc-L-homoserine ethyl ester
  • HY-P2853A

    Biochemical Assay Reagents Others
    Hemocyanin-SMCC is a hemocyanin that can be used as a carrier protein to couple low molecular weight molecules such as peptides, nucleic acids, drugs or toxins to make them highly immunogenic.
    Hemocyanin-SMCC
  • HY-W134327A

    Diethylaminoethyl dextran (MW 500000)

    Biochemical Assay Reagents Others
    DEAE-Dextran (MW 500000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds and modified with diethylaminoethyl (DEAE) groups. DEAE-Dextran is a cationic molecule that can be used as a transfection reagent to deliver nucleic acids such as DNA or RNA into cells. Its positive charge interacts with negatively charged cell membranes, facilitating the uptake of nucleic acids. DEAE-Dextran can also be used as an ion-exchange chromatography resin, allowing the separation and purification of biomolecules based on their charge.
    DEAE-dextran (MW 500000)
  • HY-D2205

    Cy7 TSA

    Fluorescent Dye Others
    Cy7 tyramide, a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids.
    Cy7 tyramide
  • HY-P3023A

    Biochemical Assay Reagents Others
    Mutanolysin, streptomyces globisporus ATCC21553 (0.2 μm filtered) is an N-acetylmuramidase that can be used to prepare nucleic acids and intact ribosomal RNA from Gram-positive bacteria .
    Mutanolysin, streptomyces globisporus ATCC21553 (0.2 μm filtered)

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