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Results for "

natriuretic peptide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Natriuretic Peptide Receptor (NPR) (16) Androgen Receptor (1) Angiotensin Receptor (6) Angiotensin-converting Enzyme (ACE) (4) Apoptosis (3) Biochemical Assay Reagents (1) Calcium Channel (2) Drug Derivative (1) Drug Metabolite (1) Endogenous Metabolite (4) Endothelin Receptor (9) FGFR (2) Fluorescent Dye (1) Guanylate Cyclase (3) Histamine Receptor (2) Isotope-Labeled Compounds (1) JAK (1) Kallikrein (2) Monoamine Oxidase (2) Neprilysin (10) PKC (1) PKG (2) Prolyl Endopeptidase (PREP) (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (55) Endocrinology (12) Infection (4) Inflammation/Immunology (1) Metabolic Disease (10) Neurological Disease (8)

By Targets:

Natriuretic Peptide Receptor (NPR) (16)

Androgen Receptor (1)

Angiotensin Receptor (6)

Angiotensin-converting Enzyme (ACE) (4)

Apoptosis (3)

Biochemical Assay Reagents (1)

Calcium Channel (2)

Drug Derivative (1)

Drug Metabolite (1)

Endogenous Metabolite (4)

Endothelin Receptor (9)

FGFR (2)

Fluorescent Dye (1)

Guanylate Cyclase (3)

Histamine Receptor (2)

Isotope-Labeled Compounds (1)

JAK (1)

Kallikrein (2)

Monoamine Oxidase (2)

Neprilysin (10)

PKC (1)

PKG (2)

Prolyl Endopeptidase (PREP) (1)

By Research Areas:

Cancer (3)

Cardiovascular Disease (55)

Endocrinology (12)

Infection (4)

Inflammation/Immunology (1)

Metabolic Disease (10)

Neurological Disease (8)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Nesiritide Brain natriuretic peptide-32 human; BNP-32	Natriuretic Peptide Receptor (NPR) Calcium Channel	Cardiovascular Disease
Nesiritide (Brain Natriuretic Peptide-32 human) is a recombinant human B-type natriuretic peptide. Nesiritide is a NPRs agonist, with K_d values of 7.3 and 13 pM for NPR-A and NPR-C, respectively. Nesiritide regulates V_1/2 activation/inactivation of the L-type calcium channel. Nesiritide shows vasodilatory, diuretic, and natriuretic activities. Nesiritide is used in cardiovascular diseases such as heart failure and vascular remodeling after arterial injury .

*C-Type Natriuretic* Peptide (1-53), human TFA**	Angiotensin Receptor	Cardiovascular Disease Endocrinology
C-Type Natriuretic Peptide (1-53), human TFA is the 1-53 fragment of C-Type Natriuretic Peptide. C-Type Natriuretic Peptide TFA is natriuretic peptide family peptide that is involved in the maintenance of electrolyte-fluid balance and vascular tone .

*Brain Natriuretic* Peptide-45, mouse** BNP-45, mouse	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
Brain Natriuretic Peptide-45, mouse (BNP-45, mouse) is a circulating form of mouse brain natriuretic peptide isolated from mouse heart with potent hypotensive and natriuretic potency .

Brain natriuretic peptide BNP (1-32), human	Angiotensin Receptor	Cardiovascular Disease
Brain natriuretic peptide inhibits angiotensin II-induced blood pressure. Brain natriuretic peptide can be used in the control of blood pressure .

*Atrial Natriuretic* Peptide (1-28), human, porcine, Biotin-labeled**	Fluorescent Dye	Cardiovascular Disease Endocrinology
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .

*[Tyr8]-Atrial Natriuretic* Peptide (5-27), rat**	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease Endocrinology
[Tyr8]-Atrial Natriuretic Peptide (5-27), rat is an atrial natriuretic peptide (ANP) analog that relaxes smooth muscle without affecting cGMP levels .

Nesiritide acetate Brain natriuretic peptide-32 human acetate; BNP-32 acetate	Natriuretic Peptide Receptor (NPR) Calcium Channel	Cardiovascular Disease
Nesiritide (Brain Natriuretic Peptide-32 human) acetate is a recombinant human B-type natriuretic peptide. Nesiritide acetate is a NPRs agonist, with K_d values of 7.3 and 13 pM for NPR-A and NPR-C, respectively. Nesiritide acetate regulates V_1/2 activation/inactivation of the L-type calcium channel. Nesiritide acetate shows vasodilatory, diuretic, and natriuretic activities. Nesiritide acetate is used in cardiovascular diseases such as heart failure and vascular remodeling after arterial injury .

*C-Type Natriuretic* Peptide (1-53), human**	Angiotensin Receptor	Cardiovascular Disease Endocrinology
C-Type Natriuretic Peptide (1-53), human is the 1-53 fragment of C-Type Natriuretic Peptide. C-Type Natriuretic Peptide is natriuretic peptide family peptide that is involved in the maintenance of electrolyte-fluid balance and vascular tone .

*Atrial Natriuretic* Peptide (7-28), human, canine**	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
Atrial Natriuretic Peptide (7-28), human, canine is a peptide fragment of atrial natriuretic peptide, can be used as a peptide tag .

*Brain Natriuretic* Peptide-45, rat** BNP-45, rat	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
Brain Natriuretic Peptide-45, rat (BNP-45, rat) is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency .

*Brain Natriuretic* Peptide-45, rat TFA** BNP-45, rat TFA	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
Brain Natriuretic Peptide-45, rat TFA (BNP-45, rat TFA) is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency .

*C-Type Natriuretic* Peptide (CNP) (1-22), human** 2 Publications Verification	Histamine Receptor	Cardiovascular Disease Neurological Disease Metabolic Disease
C-Type Natriuretic Peptide (CNP) (1-22), human, a 1-22 fragment of CNP, is a natriuretic peptide receptor B (NPR-B) agonist. C-Type Natriuretic Peptide (CNP) (1-22), human inhibits cAMP synthesis stimulated by the physiological agonists histamine and 5-HT or directly by Forskolin. CNP is a potent, endothelial-derived relaxant and growthinhibitory factor .

*C-Type Natriuretic* Peptide (CNP) (1-22), human TFA** 2 Publications Verification	Histamine Receptor Endothelin Receptor	Cardiovascular Disease Neurological Disease Metabolic Disease
C-Type Natriuretic Peptide (CNP) (1-22), human (TFA),a 1-22 fragment of CNP, is a natriuretic peptide receptor B (NPR-B) agonist. C-Type Natriuretic Peptide (CNP) (1-22), human (TFA) inhibits cAMP synthesis stimulated by the physiological agonists histamine and 5-HT or directly by Forskolin. CNP is a potent, endothelial-derived relaxant and growthinhibitory factor .

*Atrial natriuretic* peptide (3-28) (human)** ANP (3-28) (human)	Endothelin Receptor	Cardiovascular Disease Metabolic Disease
Atrial natriuretic peptide (3-28) (human) (ANP (3-28) (human)) is a peptide hormone that is synthesized and secreted by the atrial myocardium. Atrial natriuretic peptide (3-28) (human) is involved in the regulation of blood pressure, fluid balance, and electrolyte homeostasis .

BNP (1-21), Pro (Human)	Natriuretic Peptide Receptor (NPR)	Others
BNP (1-21), Pro (Human) is a peptide containg 21 amino acids. B-Type Natriuretic Peptide (BNP), a cardiac natriuretic hormone. BNP together with the highly homologous atrial natriuretic peptide, it forms a dual natriuretic peptide system of the heart. BNP is responsible for changes in the heart organogenesis and is associated with transition to extrauterine life .

Carperitide Atrial natriuretic peptide (ANP) (1-28), human, porcine	Endothelin Receptor	Cardiovascular Disease Endocrinology
Carperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) inhibits endothelin-1 secretion in a dose-dependent way.

*C-Type Natriuretic* Peptide (1-53), Porcine, Rat,mouse**	Endogenous Metabolite	Cardiovascular Disease
C-Type Natriuretic Peptide (1-53), Porcine, Rat, mouse is an activator of particulate guanylate cyclase B (pGC-B), which is highly expressed in endothelial cells, kidneys, and the heart. C-Type Natriuretic Peptide (1-53), Porcine, Rat, mouse can mediate a potent anti-fibrotic effect in human cardiac and renal fibroblasts by generating the second messenger cGMP .

*Atrial Natriuretic* Peptide (ANP) (1-28), rat, mouse** Atrial natriuretic factor (1-28) (rat, mouse)	Endothelin Receptor	Cardiovascular Disease Endocrinology
Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner.

*Brain Natriuretic* Peptide (1-32), rat acetate** BNP (1-32), rat acetate	Angiotensin Receptor	Cardiovascular Disease
Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes) .

*Brain Natriuretic* Peptide (1-32), rat** BNP (1-32), rat	Angiotensin Receptor	Cardiovascular Disease
Brain Natriuretic Peptide (1-32), rat (BNP (1-32), rat) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes) .

*Atrial Natriuretic* Peptide (ANP) (1-28), rat, mouse TFA** Atrial natriuretic factor (1-28) (rat, mouse) TFA	Endothelin Receptor	Cardiovascular Disease Endocrinology
Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse (TFA) is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner.

Carperitide acetate 3 Publications Verification Atrial natriuretic peptide (ANP) (1-28), human, porcine acetate	Endothelin Receptor	Cardiovascular Disease Endocrinology
Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide acetate inhibits endothelin-1 secretion in a dose-dependent way.

L-Cyclohexylalanine	Drug Derivative	Cardiovascular Disease
L-Cyclohexylalanine is an amino acid derivative. L-Cyclohexylalanine modifies an atrial natriuretic peptide, regulates homeostasis of body fluid and blood pressure homeostasis and vasodilation activity .

Vasonatrin Peptide (VNP)	PKG	Cardiovascular Disease
Vasonatrin Peptide (VNP) is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). Vasonatrin peptide possesses the venodilating actions of CNP, the natriuretic actions of ANP, and unique arterial vasodilating actions not associated with either ANP or CNP. Vasonatrin Peptide protects the diabetic heart against ischemia-reperfusion injury by inhibiting ER stress via the cGMP-PKG signaling pathway .

Candoxatrilat UK 73967	Neprilysin	Cardiovascular Disease Endocrinology
Candoxatrilat (UK 73967) is an orally active inhibitor of neutral endopeptidase. By elevating the levels of atrial natriuretic peptides, Candoxatrilat exerts its diuretic and natriuretic effects. Candoxatrilat is utilized in the research of heart failure .

Vasonatrin Peptide (VNP) TFA	PKG	Metabolic Disease
Vasonatrin Peptide (VNP) TFA is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). Vasonatrin peptide TFA possesses the venodilating actions of CNP, the natriuretic actions of ANP, and unique arterial vasodilating actions not associated with either ANP or CNP. Vasonatrin Peptide TFA protects the diabetic heart against ischemia-reperfusion injury by inhibiting ER stress via the cGMP-PKG signaling pathway .

BNP(1-32), porcine pBNP-32	Natriuretic Peptide Receptor (NPR)	Neurological Disease
BNP(1-32), porcine (pBNP-32) is a cardiac hormone. BNP(1-32), porcine is an atrial natriuretic peptide, which exhibits natriuretic, diuretic and vasorelaxant effects. BNP(1-32), porcine affects passive avoidance learning in rats with dopaminergic, cholinergic, α-and β-adrenergic mediation .

Cenderitide	Guanylate Cyclase	Cardiovascular Disease
Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research .

AP 811	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
AP 811 is a selective *atrial natriuretic* peptide clearance receptor (ANP-CR, NPR3) antagonist with a K_i** of 0.48 nM. AP 811 displays >20000-fold selectivity for NPR3 over NPR1. AP 811 abolishes ANP-induced pump stimulation .

AP 811 acetate	Endothelin Receptor	Cardiovascular Disease
AP 811 acetate is a selective *atrial natriuretic* peptide clearance receptor (ANP-CR, NPR3) antagonist with a K_i** of 0.48 nM. AP 811 acetate displays >20000-fold selectivity for NPR3 over NPR1. AP 811 acetate abolishes ANP-induced pump stimulation .

Ularitide Urodilatin (human)	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
Ularitide (Urodilatin), natriuretic peptide, is a vasodilator. Ularitide binds to and activates renal receptors. Ularitide also regulates renal dopamine metabolism Ularitide can be used in the research of heart failure .

Sacubitril sodium 2 Publications Verification AHU-377 sodium	Neprilysin	Infection Cardiovascular Disease
Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC₅₀ of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19 .

SCH-42354	Neprilysin	Cardiovascular Disease
SCH-42354 is a potent, orally active neutral endopeptidase (NEP) inhibitor, is the pharmacologically active form of the proagent SCH-42495. SCH-42354 inhibits the hydrolysis of NEP to enhance the activity of atrial natriuretic peptide (ANP). SCH-42354 inhibits hydrolysis of leu-enkephalin and ANF with IC₅₀ values of 8.3 nM and 10.0 nM, respectively. SCH-42354 has antihypertensive activity .

Sacubitril (sodium) (Standard)	Neprilysin	Infection Cardiovascular Disease
Sacubitril (sodium) (Standard) is the analytical standard of Sacubitril (sodium). This product is intended for research and analytical applications. Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19 .

Alatrioprilat	Neprilysin Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Alatrioprilat is an orally active inhibitor of angiotensin-converting enzyme (ACE) (IC₅₀=19.6 nM; K_i=9.8 nM) and enkephailnase (IC₅₀=6.1 nM; K_i=5.1 nM). Alatrioprilat plays a key role in the metabolism of hormonal peptides through the degradation of nitric oxide and atrial natriuretic factor (ANF). Alatrioprilat can be used in the study of cardiovascular diseases .

ANP (1-30), frog	Endothelin Receptor	Cardiovascular Disease Endocrinology
ANP (1-30), frog is a peptide fragment of atrial natriuretic peptide derived from frog. ANP (1-30), frog has natriuretic, diuretic, and vasorelaxant effects.

Atrial natriuretic factor (1-28) (human, porcine) Atrial natriuretic peptide (1-28)	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Atrial natriuretic factor (1-28) (human, porcine) exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human, porcine) inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human, porcine) increases cGMP levels in RMIC cells with an IC₅₀ of 1.2 nM .

CNP-38	Angiotensin Receptor	Cardiovascular Disease
CNP-38 is a C-type natriuretic peptide .

Atrial natriuretic factor (1-28) (human, porcine) TFA 1 Publications Verification Atrial natriuretic peptide (1-28) TFA	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Atrial natriuretic factor (1-28) (human, porcine) TFA exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human, porcine) TFA inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human, porcine) TFA increases cGMP levels in RMIC cells with an IC₅₀ of 1.2 nM .

Vosoritide BMN 111	FGFR	Others
Vosoritide (BMN 111) is a modified recombinant CNP (C-type natriuretic peptide) analogue, binds to NPR-B (natriuretic peptide receptor type B) and reduces the activity of FGFR3 (fibroblast growth factor receptor 3). Vosoritide can be used in achondroplasia and dwarfism research .

NPR-C activator 1	Guanylate Cyclase	Neurological Disease
NPR-C activator 1 (Compound 1) is a potent activator of natriuretic peptide receptor C (NPR-C). C-type natriuretic peptide (CNP) is involved in the regulation of vascular homeostasis. NPR-C activator 1 is identified as a potent agonist (EC₅₀ ∼ 1 μM) with promising in vivo pharmacokinetic properties .

BNP(7-32), porcine pBNP-26	Biochemical Assay Reagents	Others
BNP (7-32), porcine (pBNP-26) is an atrial natriuretic peptide, which utilized in radioimmunoassay .

Atriopeptin I (rat, mouse)	Androgen Receptor	Endocrinology
Atriopeptin I rat, mouse is an atrial natriuretic peptide, which stimulates the testosterone production with half-maximum stimulation of 38 nM .

SQ28603 SQ28,603; Squibb 28603	Neprilysin	Metabolic Disease
SQ28603 is a potent and selective inhibitor of neutral endopeptidase 3.4.24.11 (NEP), an enzyme that degrades atrial natriuretic peptide (ANP).

Vosoritide acetate BMN 111 acetate	FGFR	Others
Vosoritide (BMN 111) acetate is a natriuretic peptide receptor 2 (NPR2) agonist that acts on the proliferation and differentiation of chondrocytes to promote bone growth .

ANP [Des18-22] 4-23 amide (rat)	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
ANP [Des18-22] 4-23 amide rat is a polypeptide fragment of rat atrial natriuretic peptide (ANP) that specifically binds NPR-C .

Cat. No.	Product Name	Type

HY-163551

BNP peptide/KLH

Biochemical Assay Reagents

The BNP peptide/KLH is an antigen-adjuvant conjugate formed by linking BNP peptide (human brain natriuretic peptide) with keyhole limpet hemocyanin (KLH). By conjugating the antigen with a protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or damage the major epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.

Cat. No.	Product Name	Target	Research Area

HY-P0003

Nesiritide Brain natriuretic peptide-32 human; BNP-32	Natriuretic Peptide Receptor (NPR) Calcium Channel	Cardiovascular Disease
Nesiritide (Brain Natriuretic Peptide-32 human) is a recombinant human B-type natriuretic peptide. Nesiritide is a NPRs agonist, with K_d values of 7.3 and 13 pM for NPR-A and NPR-C, respectively. Nesiritide regulates V_1/2 activation/inactivation of the L-type calcium channel. Nesiritide shows vasodilatory, diuretic, and natriuretic activities. Nesiritide is used in cardiovascular diseases such as heart failure and vascular remodeling after arterial injury .

HY-P1815A

*C-Type Natriuretic* Peptide (1-53), human TFA**	Angiotensin Receptor	Cardiovascular Disease Endocrinology
C-Type Natriuretic Peptide (1-53), human TFA is the 1-53 fragment of C-Type Natriuretic Peptide. C-Type Natriuretic Peptide TFA is natriuretic peptide family peptide that is involved in the maintenance of electrolyte-fluid balance and vascular tone .

HY-P2469

*Brain Natriuretic* Peptide-45, mouse** BNP-45, mouse	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
Brain Natriuretic Peptide-45, mouse (BNP-45, mouse) is a circulating form of mouse brain natriuretic peptide isolated from mouse heart with potent hypotensive and natriuretic potency .

HY-129067

Brain natriuretic peptide BNP (1-32), human	Angiotensin Receptor	Cardiovascular Disease
Brain natriuretic peptide inhibits angiotensin II-induced blood pressure. Brain natriuretic peptide can be used in the control of blood pressure .

HY-P3774

*[Tyr8]-Atrial Natriuretic* Peptide (5-27), rat**	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease Endocrinology
[Tyr8]-Atrial Natriuretic Peptide (5-27), rat is an atrial natriuretic peptide (ANP) analog that relaxes smooth muscle without affecting cGMP levels .

HY-P0003A

Nesiritide acetate Brain natriuretic peptide-32 human acetate; BNP-32 acetate	Natriuretic Peptide Receptor (NPR) Calcium Channel	Cardiovascular Disease
Nesiritide (Brain Natriuretic Peptide-32 human) acetate is a recombinant human B-type natriuretic peptide. Nesiritide acetate is a NPRs agonist, with K_d values of 7.3 and 13 pM for NPR-A and NPR-C, respectively. Nesiritide acetate regulates V_1/2 activation/inactivation of the L-type calcium channel. Nesiritide acetate shows vasodilatory, diuretic, and natriuretic activities. Nesiritide acetate is used in cardiovascular diseases such as heart failure and vascular remodeling after arterial injury .

HY-P5059

Dendroaspis Natriuretic Peptide	Peptides	Cardiovascular Disease
Dendroaspis Natriuretic Peptide is a vasodilator peptide that can be isolated from animal venom .

HY-P1815

*C-Type Natriuretic* Peptide (1-53), human**	Angiotensin Receptor	Cardiovascular Disease Endocrinology
C-Type Natriuretic Peptide (1-53), human is the 1-53 fragment of C-Type Natriuretic Peptide. C-Type Natriuretic Peptide is natriuretic peptide family peptide that is involved in the maintenance of electrolyte-fluid balance and vascular tone .

HY-P3763

*Atrial Natriuretic* Peptide (7-28), human, canine**	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
Atrial Natriuretic Peptide (7-28), human, canine is a peptide fragment of atrial natriuretic peptide, can be used as a peptide tag .

HY-P1573

*Brain Natriuretic* Peptide-45, rat** BNP-45, rat	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
Brain Natriuretic Peptide-45, rat (BNP-45, rat) is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency .

HY-P2491

*Atrial Natriuretic* Peptide (1-28), human, porcine, Biotin-labeled**	Fluorescent Dye	Cardiovascular Disease Endocrinology
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .

HY-P1573A

*Brain Natriuretic* Peptide-45, rat TFA** BNP-45, rat TFA	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
Brain Natriuretic Peptide-45, rat TFA (BNP-45, rat TFA) is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency .

HY-P1237

*C-Type Natriuretic* Peptide (CNP) (1-22), human** 2 Publications Verification	Histamine Receptor	Cardiovascular Disease Neurological Disease Metabolic Disease
C-Type Natriuretic Peptide (CNP) (1-22), human, a 1-22 fragment of CNP, is a natriuretic peptide receptor B (NPR-B) agonist. C-Type Natriuretic Peptide (CNP) (1-22), human inhibits cAMP synthesis stimulated by the physiological agonists histamine and 5-HT or directly by Forskolin. CNP is a potent, endothelial-derived relaxant and growthinhibitory factor .

HY-P1237A

*C-Type Natriuretic* Peptide (CNP) (1-22), human TFA** 2 Publications Verification	Histamine Receptor Endothelin Receptor	Cardiovascular Disease Neurological Disease Metabolic Disease
C-Type Natriuretic Peptide (CNP) (1-22), human (TFA),a 1-22 fragment of CNP, is a natriuretic peptide receptor B (NPR-B) agonist. C-Type Natriuretic Peptide (CNP) (1-22), human (TFA) inhibits cAMP synthesis stimulated by the physiological agonists histamine and 5-HT or directly by Forskolin. CNP is a potent, endothelial-derived relaxant and growthinhibitory factor .

HY-P5792

*Atrial natriuretic* peptide (3-28) (human)** ANP (3-28) (human)	Endothelin Receptor	Cardiovascular Disease Metabolic Disease
Atrial natriuretic peptide (3-28) (human) (ANP (3-28) (human)) is a peptide hormone that is synthesized and secreted by the atrial myocardium. Atrial natriuretic peptide (3-28) (human) is involved in the regulation of blood pressure, fluid balance, and electrolyte homeostasis .

HY-P3758

BNP (1-21), Pro (Human)	Natriuretic Peptide Receptor (NPR)	Others
BNP (1-21), Pro (Human) is a peptide containg 21 amino acids. B-Type Natriuretic Peptide (BNP), a cardiac natriuretic hormone. BNP together with the highly homologous atrial natriuretic peptide, it forms a dual natriuretic peptide system of the heart. BNP is responsible for changes in the heart organogenesis and is associated with transition to extrauterine life .

HY-P1235

Carperitide Atrial natriuretic peptide (ANP) (1-28), human, porcine	Endothelin Receptor	Cardiovascular Disease Endocrinology
Carperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) inhibits endothelin-1 secretion in a dose-dependent way.

HY-P10720

*C-Type Natriuretic* Peptide (1-53), Porcine, Rat,mouse**	Endogenous Metabolite	Cardiovascular Disease
C-Type Natriuretic Peptide (1-53), Porcine, Rat, mouse is an activator of particulate guanylate cyclase B (pGC-B), which is highly expressed in endothelial cells, kidneys, and the heart. C-Type Natriuretic Peptide (1-53), Porcine, Rat, mouse can mediate a potent anti-fibrotic effect in human cardiac and renal fibroblasts by generating the second messenger cGMP .

HY-P10278

Anantin	Peptides	Endocrinology
Anantin binds competitively to the *receptor of atrial natriuretic* factor (ANF)** from bovine adrenal cortex (K_d = 0.6 μM) and acts as natriuretic peptide receptor A antagonist .

HY-P1236

*Atrial Natriuretic* Peptide (ANP) (1-28), rat, mouse** Atrial natriuretic factor (1-28) (rat, mouse)	Endothelin Receptor	Cardiovascular Disease Endocrinology
Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner.

HY-P1519B

*Brain Natriuretic* Peptide (1-32), rat acetate** BNP (1-32), rat acetate	Angiotensin Receptor	Cardiovascular Disease
Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes) .

HY-P1519

*Brain Natriuretic* Peptide (1-32), rat** BNP (1-32), rat	Angiotensin Receptor	Cardiovascular Disease
Brain Natriuretic Peptide (1-32), rat (BNP (1-32), rat) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes) .

HY-P3767

Auriculin B ANP (126-150) (Rat); Atrial natriuretic peptide(126-150)(rat)	Peptides	Cardiovascular Disease Metabolic Disease
Auriculin B (ANP (126-150) (Rat)) is a rat-derived atrial natriuretic peptide. Auriculin B has potent vasodilatory and diuretic properties .

HY-P1236A

*Atrial Natriuretic* Peptide (ANP) (1-28), rat, mouse TFA** Atrial natriuretic factor (1-28) (rat, mouse) TFA	Endothelin Receptor	Cardiovascular Disease Endocrinology
Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse (TFA) is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner.

HY-P1235A

Carperitide acetate 3 Publications Verification Atrial natriuretic peptide (ANP) (1-28), human, porcine acetate	Endothelin Receptor	Cardiovascular Disease Endocrinology
Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide acetate inhibits endothelin-1 secretion in a dose-dependent way.

HY-W002450

L-Cyclohexylalanine	Drug Derivative	Cardiovascular Disease
L-Cyclohexylalanine is an amino acid derivative. L-Cyclohexylalanine modifies an atrial natriuretic peptide, regulates homeostasis of body fluid and blood pressure homeostasis and vasodilation activity .

HY-P1556

Vasonatrin Peptide (VNP)	PKG	Cardiovascular Disease
Vasonatrin Peptide (VNP) is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). Vasonatrin peptide possesses the venodilating actions of CNP, the natriuretic actions of ANP, and unique arterial vasodilating actions not associated with either ANP or CNP. Vasonatrin Peptide protects the diabetic heart against ischemia-reperfusion injury by inhibiting ER stress via the cGMP-PKG signaling pathway .

HY-P1556A

Vasonatrin Peptide (VNP) TFA	PKG	Metabolic Disease
Vasonatrin Peptide (VNP) TFA is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). Vasonatrin peptide TFA possesses the venodilating actions of CNP, the natriuretic actions of ANP, and unique arterial vasodilating actions not associated with either ANP or CNP. Vasonatrin Peptide TFA protects the diabetic heart against ischemia-reperfusion injury by inhibiting ER stress via the cGMP-PKG signaling pathway .

HY-P10259

BNP(1-32), porcine pBNP-32	Natriuretic Peptide Receptor (NPR)	Neurological Disease
BNP(1-32), porcine (pBNP-32) is a cardiac hormone. BNP(1-32), porcine is an atrial natriuretic peptide, which exhibits natriuretic, diuretic and vasorelaxant effects. BNP(1-32), porcine affects passive avoidance learning in rats with dopaminergic, cholinergic, α-and β-adrenergic mediation .

HY-P3624

Cenderitide	Guanylate Cyclase	Cardiovascular Disease
Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research .

HY-P1419

AP 811	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
AP 811 is a selective *atrial natriuretic* peptide clearance receptor (ANP-CR, NPR3) antagonist with a K_i** of 0.48 nM. AP 811 displays >20000-fold selectivity for NPR3 over NPR1. AP 811 abolishes ANP-induced pump stimulation .

HY-P1419A

AP 811 acetate	Endothelin Receptor	Cardiovascular Disease
AP 811 acetate is a selective *atrial natriuretic* peptide clearance receptor (ANP-CR, NPR3) antagonist with a K_i** of 0.48 nM. AP 811 acetate displays >20000-fold selectivity for NPR3 over NPR1. AP 811 acetate abolishes ANP-induced pump stimulation .

HY-P2687

Ularitide Urodilatin (human)	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
Ularitide (Urodilatin), natriuretic peptide, is a vasodilator. Ularitide binds to and activates renal receptors. Ularitide also regulates renal dopamine metabolism Ularitide can be used in the research of heart failure .

HY-P3762

ANP (1-30), frog	Endothelin Receptor	Cardiovascular Disease Endocrinology
ANP (1-30), frog is a peptide fragment of atrial natriuretic peptide derived from frog. ANP (1-30), frog has natriuretic, diuretic, and vasorelaxant effects.

HY-P3060

Atriopeptin II (rat, mouse)	Peptides	Cardiovascular Disease
Atriopeptin II rat, mouse is an atrial natriuretic peptide, which acts as diuretic and natriuretic agent, and a potent relaxant of vascular smooth muscle .

HY-P2281

Atrial natriuretic factor (1-28) (human, porcine) Atrial natriuretic peptide (1-28)	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Atrial natriuretic factor (1-28) (human, porcine) exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human, porcine) inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human, porcine) increases cGMP levels in RMIC cells with an IC₅₀ of 1.2 nM .

HY-P5127

CNP-38	Angiotensin Receptor	Cardiovascular Disease
CNP-38 is a C-type natriuretic peptide .

HY-P2281A

Atrial natriuretic factor (1-28) (human, porcine) TFA 1 Publications Verification Atrial natriuretic peptide (1-28) TFA	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Atrial natriuretic factor (1-28) (human, porcine) TFA exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human, porcine) TFA inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human, porcine) TFA increases cGMP levels in RMIC cells with an IC₅₀ of 1.2 nM .

HY-P3503

Vosoritide BMN 111	FGFR	Others
Vosoritide (BMN 111) is a modified recombinant CNP (C-type natriuretic peptide) analogue, binds to NPR-B (natriuretic peptide receptor type B) and reduces the activity of FGFR3 (fibroblast growth factor receptor 3). Vosoritide can be used in achondroplasia and dwarfism research .

HY-P10260

BNP(7-32), porcine pBNP-26	Biochemical Assay Reagents	Others
BNP (7-32), porcine (pBNP-26) is an atrial natriuretic peptide, which utilized in radioimmunoassay .

HY-P10248

Atriopeptin I (rat, mouse)	Androgen Receptor	Endocrinology
Atriopeptin I rat, mouse is an atrial natriuretic peptide, which stimulates the testosterone production with half-maximum stimulation of 38 nM .

HY-P3503A

Vosoritide acetate BMN 111 acetate	FGFR	Others
Vosoritide (BMN 111) acetate is a natriuretic peptide receptor 2 (NPR2) agonist that acts on the proliferation and differentiation of chondrocytes to promote bone growth .

HY-P4906

Atrial Natriuretic Factor (5-27) (human)	Peptides	Others
Atrial Natriuretic Factor (5-27) (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P1526

ANP [Des18-22] 4-23 amide (rat)	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
ANP [Des18-22] 4-23 amide rat is a polypeptide fragment of rat atrial natriuretic peptide (ANP) that specifically binds NPR-C .

HY-120521

Urodilatin	Natriuretic Peptide Receptor (NPR)	Neurological Disease
Urodilatin is an analogue of ANF-(99-126). Urodilatin is a diuretic-natriuretic regulatory peptide. Urodilatin can be used for research of acute renal failure, congestive heart failure, and bronchial asthma, etc .

HY-P1980

A-71915 TFA	Apoptosis	Metabolic Disease
A-71915 (TFA) is a selective inhibitor of ANP receptor (atrial natriuretic peptide-receptor), induces apoptosis and decreases insulin secretion in RINm5F pancreatic β-cells .

HY-P5495

Uroguanylin-15 (Rat)	Peptides	Others
Uroguanylin-15 (Rat) is a biological active peptide. (Uroguanylin is a natriuretic peptide, a hormone that regulates sodium excretion by the kidney when excess NaCl is consumed. Uroguanylin and guanylin are related peptides that activate common guanylate cyclase signaling molecules in the intestine and kidney. Uroguanylin was isolated from urine and duodenum but was not detected in extracts from the colon of rats.)

HY-P1401

Protein Kinase C (19-36)	PKC	Metabolic Disease
Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC₅₀ of 0.18 μM. Protein Kinase C (19-36) markedly attenuated vascular hyperproliferation and hypertrophy as well as glucose-induced suppression of natriuretic peptide receptor response .

HY-P3562

PL-3994	Peptides	Others
PL-3994 is a natriuretic peptide receptor-A (NPR-A) agonist that is resistant to neutral endopeptidase and acts as a bronchodilator. PL-3994 produces concentration-dependent relaxation of pre-contracted guinea-pig trachea with an IC₅₀ value of 42.7 nM .

HY-P10279

Anaritide Human atrial natriuretic factor (102–126)	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease Others
Anaritide is a synthetic form of atrial natriuretic peptide (ANP) composed of 25 amino acids. Anaritide increases glomerular filtration rate by dilating into and contracting out the bulbar arterioles. Anaritide can be used to study the effects on patients with acute tubular necrosis, particularly in improving dialysis free survival .

Species:	Human (6)
Tag:	His (5) Avi (1) Flag (1) Fc (1)
Source:	HEK293 (2) P. pastoris (1) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P700563

	Natriuretic peptides A/NPPA Protein, Human (P. pastoris, His) NPPA; natriuretic peptide A; ANP, natriuretic peptide precursor A , PND; natriuretic peptides A; atriopeptin; cardionatrin; prepronatriodilatin; natriuretic peptide precursor A; ANF; ANP; PND; ATFB6; CDD-ANF;	Human	P. pastoris
	Natriuretic peptide A/NPPA is critical for cardiorenal homeostasis and regulates vascular remodeling and energy metabolism by binding to NPR1. This stimulates the production of c, activating PRKG1 to respond differently. Natriuretic peptides A/NPPA Protein, Human (P. pastoris, His) is the recombinant human-derived Natriuretic peptides A/NPPA protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P71119A

	NPPB Protein, Human (His) natriuretic peptides B; Gamma-Brain natriuretic peptide; NPPB	Human	E. coli
	NPPB proteins are members of the natriuretic peptide family and are key regulators of cardiovascular homeostasis. As a hormone, NPPB is produced and released primarily by ventricular myocytes in response to increases in pressure and volume. NPPB Protein, Human (His) is the recombinant human-derived NPPB protein, expressed by E. coli , with N-6*His labeled tag.

HY-P71119

	NPPB Protein, Human (His, solution) natriuretic peptides B; Gamma-Brain natriuretic peptide; NPPB	Human	E. coli
	NPPB proteins are members of the natriuretic peptide family and are key regulators of cardiovascular homeostasis. As a hormone, NPPB is produced and released primarily by ventricular myocytes in response to increases in pressure and volume. NPPB Protein, Human (His, solution) is the recombinant human-derived NPPB protein, expressed by E. coli , with N-6*His labeled tag.

HY-P71120

	NPPB Protein, Human (76a.a, Flag-His) natriuretic peptides B; Gamma-brain natriuretic peptide; NPPB; BNP; NT-proBNP	Human	E. coli
	NPPB proteins are members of the natriuretic peptide family and are key regulators of cardiovascular homeostasis. As a hormone, NPPB is produced and released primarily by ventricular myocytes in response to increases in pressure and volume. NPPB Protein, Human (76a.a, Flag-His) is the recombinant human-derived NPPB protein, expressed by E. coli , with N-6*His, N-Flag labeled tag.

HY-P703923

	NPR1 Protein, Human (HEK293, Fc) Atrial natriuretic peptide receptor 1; NPR1; NPRA; GC-A; ANPRA; NPR-A	Human	HEK293

HY-P704143

	NPR1/NPRA Protein, Human (Biotinylated, HEK293, His, Avi) Atrial natriuretic peptide receptor 1; NPR1; NPRA; GC-A; ANPRA; NPR-A	Human	HEK293

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HY-P81636

	Natriuretic Peptides A Antibody (YA1381) ANF antibody; ANF_HUMAN antibody; ANP antibody; ATFB6 antibody; Atrial natriuretic factor antibody; Atrial natriuretic peptide antibody; Atriopeptin antibody; Cardiodilatin antibody; Cardiodilatin related peptide antibody; Cardiodilatin-related peptide antibody; Cardionatrin antibody; CDD ANF antibody; CDD antibody; CDD-ANF antibody; CDP antibody; natriuretic peptide A antibody; natriuretic peptide precursor A antibody; NPPA antibody; PND antibody; Prepronatriodilatin antibody	WB, IP	Human
	Natriuretic Peptides A Antibody (YA1381) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1381), targeting Natriuretic Peptides A, with a predicted molecular weight of 16 kDa (observed band size: 16 kDa). Natriuretic Peptides A Antibody (YA1381) can be used for WB, IP experiment in human background.

HY-P84648

	BNP Antibody (YA4345) Brain natriuretic peptide 32 antibody; Brain type natriuretic peptide antibody; Gamma brain natriuretic peptide antibody; natriuretic peptide B antibody; natriuretic peptide precursor B antibody; natriuretic peptide, brain type antibody; natriuretic peptides B antibody; natriuretic protein antibody; NPPB antibody	WB, IHC-P	Human, Mouse, Rat
	BNP Antibody (YA4345) is a non-conjugated and Rabbit origined monoclonal antibody about 37 kDa, targeting to BNP. It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P81288

	Natriuretic Peptides B Antibody (YA999) NPPB; natriuretic peptides B; Gamma-brain natriuretic peptide	ELISA	Human
	Natriuretic Peptides B Antibody (YA999) is a mouse-derived non-conjugated IgG2b antibody (Clone NO.: YA999), targeting Natriuretic Peptides B. Natriuretic Peptides B Antibody (YA999) can be used for ELISA experiment in human background.

HY-P81288A

	Natriuretic Peptides B Antibody (YA1000) NPPB; natriuretic peptides B; Gamma-brain natriuretic peptide	ELISA	Human
	Natriuretic Peptides B Antibody (YA1000) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA1000), targeting Natriuretic Peptides B. Natriuretic Peptides B Antibody (YA1000) can be used for ELISA experiment in human background.

HY-P81288B

	Natriuretic Peptides B Antibody (YA1001) NPPB; natriuretic peptides B; Gamma-brain natriuretic peptide	ELISA	Human
	Natriuretic Peptides B Antibody (YA1001) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA1001), targeting Natriuretic Peptides B. Natriuretic Peptides B Antibody (YA1001) can be used for ELISA experiment in human background.

HY-P85064

	BNP Antibody (YA4756) NPPB; natriuretic peptides B; Gamma-brain natriuretic peptide	IHC-P, ICC/IF, ELISA	Human

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