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Pathways Recommended:	Anti-infection

Results for "

antifungal infection

" in MedChemExpress (MCE) Product Catalog:

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148

Inhibitors & Agonists

Screening Libraries

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148160A

Diamthazole hydrochloride Dimazole hydrochloride	Fungal	Infection
Diamthazole (Dimazole) hydrochloride is an antifungal agent. Diamthazole hydrochloride can be used for the research of infection .

HY-107126

Ibrexafungerp MK 3118; SCY-078	Fungal	Infection
Ibrexafungerp (MK 3118) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp can be used for research of Candida and Aspergillus infections .

HY-14283

Luliconazole 1 Publications Verification NND 502	Fungal Antibiotic	Infection
Luliconazole (NND 502) is a topical antifungal imidazole antibiotic with broad-spectrum and potent antifungal activity. Luliconazole can be used for the research of skin infection, including dermatophytosis, tinea corporis, tinea pedis et al .

HY-148160

Diamthazole Dimazole	Fungal	Infection
Diamthazole (Dimazole) is an antifungal agent. Diamthazole can be used for the research of infection .

HY-168108

Antifungal agent 115	Fungal	Infection
Antifungal agent 115 (compound 8n) is a non-competitive chitin synthase (CHS) inhibitor with an IC₅₀ of 93 μM. Antifungal agent 115 demonstrates good selectivity and broad-spectrum *antifungal* activity, exhibiting significant efficacy against drug-resistant fungi. Antifungal agent 115 can be utilized in fungi infection research .

HY-151418

Chitin synthase inhibitor 8	Fungal	Infection
Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal activity. Chitin synthase inhibitor 8 can be used in the research of fungi infection .

HY-151419

Chitin synthase inhibitor 9	Fungal	Infection
Chitin synthase inhibitor 9 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal activity. Chitin synthase inhibitor 9 can be used in the research of fungi infection .

HY-107126B

Ibrexafungerp phosphate MK 3118 phosphate; SCY-078 phosphate	Fungal	Infection
Ibrexafungerp phosphate is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp phosphate can be used for research of Candida and Aspergillus infections .

HY-155198

Antifungal agent 72	Fungal	Infection
Antifungal agent 72 (Compound B8) is a potent antifungal agent. Antifungal agent 72 suppresses the function of efflux pump and down-regulates the resistance-associated genes through blocking the Pdr1-KIX interaction (K_i: 11.7 μM). Antifungal agent 72 is active against Fluconazole (HY-B0101)-resistant with a MIC value of 63 ng/mL, and shows synergistic inhibitory activity with Fluconazole. Antifungal agent 72 can be used for C. glabrata infection research .

HY-174394S

CYP51-IN-25	Isotope-Labeled Compounds Fungal Cytochrome P450	Infection
CYP51-IN-25 is a orally active broad spectrum antifungal agent with the MIC₈₀ of 0.00625-0.05 μg/mL. is a CYP51-IN-25 is a deuterated compound with antibiotic properties. CYP51-IN-25 can inhibit the fungal CYP51 enzyme, block ergosterol synthesis, and disrupt cell membrane integrity. CYP51-IN-25 can be used for research on *fungal* infections.

HY-171796

Bromomonilicin	Fungal	Infection
Bromomonilicin is a selective *fungal* cell membrane inhibitor. Bromomonilicin exerts antifungal activity by disrupting fungal cell membrane integrity. Bromomonilicin is promising for research of plant pathogenic fungal infections (e.g., Monilinia fructicola-induced brown rot) and superficial mycoses (e.g., dermatophyte infections) .

HY-124952

iKIX1	Fungal	Infection
iKIX1 is an antifungal agent and resensitizes drug-resistant C. glabrata to azole antifungals in vitro. iKIX1 inhibits the interaction between the KIX domain of the mediator subunit CgGal11A and the activation domain of CgPdr1, the IC₅₀ and K_i values are 190.2 μM and 18 μM, respectively. iKIX1 is used for the study of multidrug resistance and C. glabrata infection .

HY-151416

Chitin synthase inhibitor 6	Fungal	Infection
Chitin synthase inhibitor 6 (compound 9b) is a potent chitin synthase (CHS) inhibitor with an IC₅₀ value of 0.21 mM. Chitin synthase inhibitor 6 has broad-spectrum antifungal activity against drug-resistant fungi. Chitin synthase inhibitor 6 can be used in the research of fungi infection .

HY-151417

Chitin synthase inhibitor 7	Fungal	Infection
Chitin synthase inhibitor 7 (compound 9c) is a potent chitin synthase (CHS) inhibitor with an IC₅₀ value of 0.37 mM. Chitin synthase inhibitor 7 has broad-spectrum antifungal activity against drug-resistant fungi. Chitin synthase inhibitor 7 can be used in the research of fungi infection .

HY-129671

Polypodine B 5β-Hydroxyecdysterone	Parasite Fungal	Infection
Polypodine B is a natural ecdysone ester isolated from the bark of Dacrydium intermedium. Polypodine B significantly inhibits the activity of *Acanthamoeba castellani. Polypodine B has moderate antifungal* activity. Polypodine B can be used for research on parasitic diseases and fungal infections .

HY-146079

Antifungal agent 31	Fungal	Infection
Antifungal agent 31 (compound 12) is a potent and orally active triazole antifungal agents with a pyrrolotriazinone scaffold. Antifungal agent 31 shows antifungal activity against Candida spp. and filamentous fungi. Antifungal agent 31 significantly reduced mortality rates and kidney fungal burden in two murine models of lethal systemic infections .

HY-14283R

Luliconazole (Standard) NND 502 (Standard)	Reference Standards Fungal Antibiotic	Infection
Luliconazole (Standard) is the analytical standard of Luliconazole. This product is intended for research and analytical applications. Luliconazole (NND 502) is a topical antifungal imidazole antibiotic with broad-spectrum and potent antifungal activity. Luliconazole can be used for the research of skin infection, including dermatophytosis, tinea corporis, tinea pedis et al .

HY-B1144A

Chlormidazole hydrochloride Clomidazole hydrochloride	Fungal	Infection
Chlormidazole hydrochloride is an antifungal agent and has inhibitory activity against many fungi and some gram-positive cocci. Chlormidazole hydrochloride can be applied in fungal and bacterial infections of nails and skin, including interdigital and periungual mycoses .

HY-W357140

β-Phenylethyl β-D-glucoside Phenylethyl β-D-glucopyranoside	Fungal	Infection
β-Phenylethyl β-D-glucoside (Phenylethyl β-D-glucopyranoside) (Compound 7), a phenolic compounds, is an antifungal agent. β-Phenylethyl β-D-glucoside can be isolated from the leaves of Piper crocatum. β-Phenylethyl β-D-glucoside has antifungal activity against Candida albicans. β-Phenylethyl β-D-glucoside can be used for fungal infections research .

HY-N15375

Trichomycin B	Antibiotic Fungal Parasite	Infection
Trichomycin B is a polyene macrolide antibiotic that can be isolated from the fermentation products of Streptomyces hachijoensis. Trichomycin B exhibits antibacterial activity against fungi, yeasts, and trichomonas. Trichomycin B can be used in research on antifungal and anti-trichomoniasis infection .

HY-B0319

Tioconazole 4 Publications Verification UK-20349	Fungal Antibiotic Parasite Akt PI3K mTOR Autophagy	Infection Cancer
Tioconazole (UK-20349) is a broad-spectrum antifungal imidazole derivative. Tioconazole inhibits several dermatophytes and yeasts, with MIC₅₀ values of less than 3.12 mg/L and 9 mg/L, respectively. Additionally, Tioconazole exhibits anti-parasitic activity. Tioconazole exerts anticancer activity by inhibiting the PI3K/AKT/mTOR signaling pathway and blocking autophagy. Tioconazole is applicable for research in the fields of anti-infection and anticancer therapy .

HY-151420

Chitin synthase inhibitor 10	Fungal	Infection Cancer
Chitin synthase inhibitor 10 is a chitin synthase inhibitor. Chitin synthase inhibitor 10 shows excellent chitin synthase inhibitory activity with an IC₅₀ value of 0.11 mM. Chitin synthase inhibitor 10 also is an antifungal agent and has significantly antifungal activity against drug-resistant fungal variants, such as C. albicans and C. neoformans. Chitin synthase inhibitor 10 can be used for the research of invasive fungal infections (IFIs) .

HY-151422

Chitin synthase inhibitor 12	Fungal	Infection Cancer
Chitin synthase inhibitor 12 is a chitin synthase inhibitor. Chitin synthase inhibitor 12 shows excellent inhibitory activity with an IC₅₀ value of 0.16 mM. Chitin synthase inhibitor 12 also is a broad-spectrum antifungal agent and has significantly antifungal activity against drug-resistant fungal variants, such as C. albicans and C. neoformans. Chitin synthase inhibitor 12 can be used for the research of invasive fungal infections (IFIs) .

HY-178330

IKE16	Others Topoisomerase	Infection
IKE16 is a fungi-selective eukaryotic topoisomerase II inhibitor, with an IC₅₀ value of 13.68 μM. IKE16 suppresses both the DNA relaxation activity and the decatenation activity of yTOPOII selectively. IKE16 shows moderate activity against standard fungal strains (Candida albicans ATCC 10231, Saccharomyces cerevisiae ATCC 89763) with a minimum inhibitory concentration (MIC) of 2 μg/mL against S. cerevisiae ATCC 89763. IKE16 exhibits high cytotoxicity against human cells, with an EC₅₀ of 0.07 μM in HepG2 and 0.045 μM in HEK-293. IKE16 can be used for the study of antifungal infection .

HY-N2925

β-Amyrone β-Amyron	Fungal COX PPAR	Infection Metabolic Disease Inflammation/Immunology
β-Amyrone (β-Amyron) is a triterpene compound which has anti-inflammatory activity through inhibiting the expression of COX-2. β-Amyrone has antifungal activity , as well as antiviral activity against Chikungunya virus. β-Amyrone also inhibits α-glucosidase and acetylcholinesterase (AChE) activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity .

HY-175198

Cs-2d	Acyltransferase Fungal	Infection
Cs-2d is a selective ceramide synthases Cer1 inhibitor. Cs-2d has potent inhibitory activity toward C. neoformans Cer1, while maintaining a low off-target effect on human hCerS1. Cs-2d has potent antifungal activity with the significant growth inhibition. Cs-2d can be used for invasive fungal infections research .

HY-175699

Antimicrobial agent-42	Fungal	Infection
Antimicrobial agent-42 (Compound 6j) is an antimicrobial agent. Antimicrobial agent-42 interacts with key amino acids such as Lys59 and Ser170 within the ALS3 protein, crucial for the binding of host peptides. Antimicrobial agent-42 significantly inhibits Candida albicans biofilm formation and reduces planktonic cells aggregation and hyphal formation. Antimicrobial agent-42 has an antifungal activity, promising for fungal infections reseach .

HY-151421

Chitin synthase inhibitor 11	Fungal	Infection Cancer
Chitin synthase inhibitor 11 is a chitin synthase inhibitor. Chitin synthase inhibitor 11 shows excellent chitin synthase inhibitory activity with an IC₅₀ value of 0.10 mM. Chitin synthase inhibitor 11 has broad-spectrum antifungal activity in vitro. Chitin synthase inhibitor 11 can be used for the research of invasive fungal infections (IFIs) .

HY-151439

Antifungal agent 41	Fungal	Infection
Antifungal agent 41 (compound B01) is an antifungal agent. Antifungal agent 41 shows inhibitory effect on Candida albicans in virto and vivo. Antifungal agent 41 can be used for the research of invasive fungal infections .

HY-B1790

Terconazole R42470	Fungal	Infection
Terconazole is a broad-spectrum *antifungal* medication for the treatment of vaginal yeast infection.

HY-B0101B

Fluconazole mesylate UK 49858 mesylate	Fungal Antibiotic Bacterial	Infection Cancer
Fluconazole (mesylate) is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.

HY-B0101A

Fluconazole hydrate UK 49858 hydrate	Fungal Antibiotic Bacterial	Infection Cancer
Fluconazole (hydrate) is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.

HY-N14979

Dermostatin A	Antibiotic Fungal	Infection
Dermostatin A is a polyene antibiotic with antifungal activity that can be used in the study of fungal infections .

HY-146116

Antifungal agent 32	Fungal	Infection
Antifungal agent 32 (compound 1a) is a potent antifungal agent. Antifungal agent 32 inhibits Candida albicans filamentation and biofilm formation. Antifungal agent 32 inhibits the morphological switching of Candida albicans and its adherence to epithelial cells. Antifungal agent 32 can be used for Candida albicans infections research .

HY-N14980

Dermostatin B	Antibiotic Fungal	Infection
Dermostatin B is a polyene antibiotic with antifungal activity that can be used in the study of fungal infections .

HY-129060

Flutrimazole 1 Publications Verification	Fungal	Infection
Flutrimazole is an imidazole antifungal with dual anti-inflammatory and antifungal activity. Flutrimazole shows scarce transdermal penetration. Flutrimazole has the advantageous in the research of topical fungal infections with an inflammatory component .

HY-178196

SDH-IN-32	Fungal MMP Apoptosis	Infection
SDH-IN-32 is a succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 2.74 μM. SDH-IN-32 exhibits excellent antifungal activity. SDH-IN-32 can destroy the cell membrane structure and increase the permeability of the cell membrane. SDH-IN-32 can decrease the mitochondrial membrane potential (MMP), thereby inducing cell apoptosis and inhibiting the normal growth of mycelia. SDH-IN-32 can be used for the research of infection .

HY-B0576

Sulfacetamide sodium 3 Publications Verification Sulphacetamide sodium	Antibiotic Bacterial Fungal	Infection Inflammation/Immunology
Sulfacetamide (Sulphacetamide) sodium is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide sodium has antifungal and antibacterial activities .

HY-B0888

Sulfacetamide sodium monohydrate 3 Publications Verification Sulphacetamide sodium monohydrate	Antibiotic Bacterial Fungal	Infection Inflammation/Immunology
Sulfacetamide (Sulphacetamide) sodium monohydrate is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide sodium monohydrate has antifungal and antibacterial activities .

HY-U00181

Fludazonium chloride R23633	Fungal	Infection
Fludazonium chloride (R23633) is an anti-fungal agent, which can be used in the treatment and prevention of superficial and systemic fungal infections.

HY-173206

Antifungal agent 128	Fungal	Infection
Antifungal agent 128 (Compound 3ja) is an antifungal agent. When used in combination with Fluconazole (HY-B0101), the MIC range against C. albicans strains is 0.5-4 μg/mL. Antifungal agent 128 can be used in the research of the anti-infection field .

HY-W1127089

Antifungal agent 136	Fungal Cytochrome P450 Interleukin Related	Infection Inflammation/Immunology
Antifungal agent 136 (Compound M-15) is an irreversible fungal lanosterol 14α-demethylase (CYP51) inhibitor. Antifungal agent 136 exhibits potent antifungal activity against drug-resistant Candida albicans and downregulates IL-6 expression. Antifungal agent 136 is promising for research of fungal infection and inflammatory disease .

HY-B1790S

Terconazole-d4 R42470-d₄	Fungal	Infection
Terconazole-d₄ is the deuterium labeled Terconazole. Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection.

HY-118847

Antifungal agent 86	Fungal	Infection
Antifungal agent 86 (Compound 41F5) is an antifungal agent. Antifungal agent 86 is highly active against Histoplasma yeast and Cryptococcus neoformans (MIC₅₀: 0.4-0.8 μM) .

HY-152896

Ys-II	Fungal	Infection
Ys-II (Compound 1) is a spirostanol glycoside that can be isolated from the stem of Yucca elephantipe. Ys-II has antifungal activity against the growth of Candida albicans and Cryptococcus neoformans (IC₅₀: 5 and 6 μg/mL respectively) .

HY-178340

Antifungal agent 137	Cytochrome P450 Fungal Reactive Oxygen Species (ROS)	Infection
Antifungal agent 137 (Compound 4S) is an antifungal agent. Antifungal agent 137 inhibits Phomopsis sp. (PS), with an EC₅₀ of 0.15 μg/mL. Antifungal agent 137 inhibits lanosterol 14α-demethylase (CYP51), with an IC₅₀ of 5.00 μg/mL. Antifungal agent 137 disrupts the morphology of PS mycelia, impairs cell membrane integrity, and induces an increase in intracellular ROS levels, triggering oxidative stress. Antifungal agent 137 can be used for the study of fungal infection .

HY-173428

Antifungal agent 130	Fungal	Infection
Antifungal agent 130 (Compound A7) is an orally active antifungal agent. Antifungal agent 130 has good antifungal activity against Candida albicans (MIC = 0.12 ng/mL) and Cryptococcus neoformans (MIC = 0.12 ng/mL) and has excellent antivirulence effect. Antifungal agent 130 exerts its antifungal effect by disrupting the iron homeostasis of fungal cells and inducing oxidative stress damage. Antifungal agent 130 can inhibit the formation of fungal virulence factors (such as biofilm, capsule, urease and melanin). Antifungal agent 130 has good antifungal effect and can be used in the study of drug-resistant fungal infections .

HY-106541

Neticonazole 1 Publications Verification	Fungal	Infection Cancer
Neticonazole is an imidazole derivative and a potent and long-acting antifungal agent. Neticonazole has anti-infection and anti-cancer effects .

HY-14603

Clioquinol 5 Publications Verification Iodochlorohydroxyquinoline	Fungal Autophagy Mitophagy Antibiotic Parasite	Infection Cancer
Clioquinol (Iodochlorhydroxyquin) is a topical antifungal agent with anticancer activity. Clioquinol acts as an oral antimicrobial agent for the research of diarrhea and skin infections. Antibiotic .

HY-128365

Neticonazole hydrochloride 1 Publications Verification	Fungal	Infection Cancer
Neticonazole hydrochloride is an imidazole derivative and a potent and long-acting antifungal agent. Neticonazole hydrochloride has anti-infection and anti-cancer effects .

Cat. No.	Product Name

HY-L048

Antifungal Compound Library

455 compounds

The high rates of morbidity and mortality caused by fungal infections are associated with the current limited antifungal arsenal and the high toxicity of the compounds. Additionally, identifying novel drug targets is challenging because there are many similarities between fungal and human cells. The most common antifungal targets include fungal RNA synthesis and cell wall and membrane components, though new antifungal targets are being investigated. Nonetheless, fungi have developed resistance mechanisms, such as overexpression of efflux pump proteins, overexpression and changes in drug targets and biofilm formation, emphasizing the importance of discovering new antifungal drugs and therapies. Due to the limited antifungal arsenal, researchers have sought to improve treatment via different approaches, such as the combination of antifungal drugs, development of new formulations for antifungal agents and modifications to the chemical structures of traditional antifungals, etc.

MCE offers a unique collection of 455 compounds with validated antifungal activities. MCE antifungal compound library is an effective tool for drug repurposing screening, combination screening and biological investigation.

HY-L002

Anti-Infection Compound Library

3,663 compounds

An infection occurs when another organism enters a person’s body and causes disease. The organisms that cause infections are very diverse and can include things like viruses, bacteria, fungi, and parasites. The immune system is an effective barrier against infectious agents.

MCE provides a unique collection of 3,663 anti-infective compounds with anti-bacterial, anti-viral, anti-fungal and anti-parasite activities that can be used for drug screening and other research in anti-microbial area.

Cat. No.	Product Name	Target	Research Area

HY-126810A

NP213 TFA	Fungal	Infection
NP213 TFA is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has *anti-fungal* activities. NP213 TFA targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 TFA is effective and well-tolerated in resolving nail fungal infections .

HY-P5705

Gageotetrin B	Fungal Bacterial	Infection
Gageotetrin B has antimicrobial activities. Gageotetrin B is more active against fungi compared to bacteria with MIC values of 0.01-0.04 μM .

HY-P10916

Micafungin metabolite M1	Drug Metabolite Fungal	Infection
Micafungin metabolite M1 is an active metabolite of Micafungin (HY-17579), which is metabolized by arylsulfatase and exhibits antifungal activity. Micafungin metabolite M1 can be used for research on deep fungal infections caused by Candida and Aspergillus species .

HY-P5564

BTL peptide	Fungal	Infection
BTL peptide is an antifungal peptide. BTL peptide is active against B. maydis, A. brassicae, A. niger and C. personata .

HY-P5569

SP-B peptide	Fungal	Infection
SP-B peptide is an antimicrobial peptide. SP-B peptide has antifungal activity against strains of Cryptococcus neoformans, Candida albicans and Aspergillus fumigatus

HY-126810

NP213	Fungal	Infection
NP213 is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has *anti-fungal* activities. NP213 targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 is effective and well-tolerated in resolving nail fungal infections .

HY-P5572

Aurein 2.5	Antibiotic Fungal Bacterial	Infection
Aurein 2.5 is an antibiotic antimicrobial peptide. Aurein 2.5 has antibacterial and antifungal activity

HY-P11031

CotH3 peptide	Fungal	Infection
CotH3 peptide is a functional peptide unique to Mucorales that binds to the host GRP78 receptor and allows them to invade endothelial cells. CotH3 peptide–targeted monoclonal antibodies protect immunosuppressed mice from mucormycosis caused by R. delemar and other Mucorales. CotH3 peptide also synergizes with *antifungal* drugs to protect mice with diabetic ketoacidosis (DKA) from R. delemar infection .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W357140

β-Phenylethyl β-D-glucoside Phenylethyl β-D-glucopyranoside	Source classification Piperaceae Piper crocatum Ruiz & Pav. Plants Saccharides Monosaccharides	Fungal
β-Phenylethyl β-D-glucoside (Phenylethyl β-D-glucopyranoside) (Compound 7), a phenolic compounds, is an antifungal agent. β-Phenylethyl β-D-glucoside can be isolated from the leaves of Piper crocatum. β-Phenylethyl β-D-glucoside has antifungal activity against Candida albicans. β-Phenylethyl β-D-glucoside can be used for fungal infections research .

HY-N2925

β-Amyrone β-Amyron	Triterpenes Caprifoliaceae Source classification Plants Sambucus adnata Wall. ex DC.	Fungal COX PPAR
β-Amyrone (β-Amyron) is a triterpene compound which has anti-inflammatory activity through inhibiting the expression of COX-2. β-Amyrone has antifungal activity , as well as antiviral activity against Chikungunya virus. β-Amyrone also inhibits α-glucosidase and acetylcholinesterase (AChE) activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity .

HY-N6647

Luteolin-7-rutinoside	Flavonoids other families Classification of Application Fields Flavones Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	Fungal
Luteolin-7-rutinoside has both anti-arthritic and antifungal activities, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.

HY-N15375

Trichomycin B	Microorganisms Antibiotics Source classification	Antibiotic Fungal Parasite
Trichomycin B is a polyene macrolide antibiotic that can be isolated from the fermentation products of Streptomyces hachijoensis. Trichomycin B exhibits antibacterial activity against fungi, yeasts, and trichomonas. Trichomycin B can be used in research on antifungal and anti-trichomoniasis infection .

HY-N14979

Dermostatin A	Microorganisms Macrolide Antibiotics Antibiotics Source classification	Antibiotic Fungal
Dermostatin A is a polyene antibiotic with antifungal activity that can be used in the study of fungal infections .

HY-N14980

Dermostatin B	Microorganisms Macrolide Antibiotics Antibiotics Source classification	Antibiotic Fungal
Dermostatin B is a polyene antibiotic with antifungal activity that can be used in the study of fungal infections .

HY-152896

Ys-II	Natural Products Source classification Yucca gigantea Lem. Plants Asparagaceae Juss.	Fungal
Ys-II (Compound 1) is a spirostanol glycoside that can be isolated from the stem of Yucca elephantipe. Ys-II has antifungal activity against the growth of Candida albicans and Cryptococcus neoformans (IC₅₀: 5 and 6 μg/mL respectively) .

HY-N12260

Benanomicin A	Quinones Microorganisms Anthraquinones Source classification	HIV Bacterial
Benanomicin A is a microbial metabolite and can be isolated from Actinomycetes.Benanomicin has antifungal activitya and inhibits HIV-1 viral infection in MT-4 cells .

HY-N12201

Funiculosin	Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Fungal
Funiculosin is a neutral lipophilic antibiotic that inhibits DNA and RNA viruses. Funiculosin also has antifungal activity. Funiculosin inhibits infections caused by pathogenic fungi in primary chicken embryo fibroblasts .

HY-N14217

Eulicin	Microorganisms Antibiotics Source classification Other Antibiotics	Fungal HIV
Eulicin is an *antifungal* agent that inhibits human immunodeficiency virus (HIV) infection and replication. Eulicin is broadly active against both Gram-positive and Gram-negative bacteria and can be found in Streptomyces .

HY-N3270

Methyl orsellinate	Natural Products Rhododendron primuliflorum Bureau & Franch. Source classification Plants Ericaceae	Fungal Lipoxygenase
Methyl orsellinate is a phytotoxic compound with antifungal activities. Methyl orsellinate is a 5-lipoxygenase inhibitor with an IC₅₀ value of 59.6 μM. Methyl orsellinate can be used for fungal infection research .

HY-N4164

Schinifoline	Zanthoxylum bungeanum Maxim. Alkaloids Classification of Application Fields Source classification Rutaceae Quinoline Alkaloids Plants Disease Research Fields Cancer	Fungal Apoptosis
Schinifoline is a 4-quinolinone found in Zanthoxylum schinifolium. Schinifoline can inhibit cancer cells proliferation, cause G2/M phase arrest and induce apoptosis. Schinifoline can improve radiosensitizing effect of cancer cells. Schinifoline shows anti-fungal activity. Schinifoline can be used for the researches of cancer and infection, such as lung cancer and C. albicans infection .

HY-N8329

AS-2077715	Microorganisms Antibiotics Source classification Other Antibiotics	Fungal Antibiotic
AS-2077715 is an antifungal agent that shows inhibitory activity against the Trichophyton species. AS-2077715 can be obtained from the fermentation broth of Capnodium sp. 339855. AS-2077715 can be used to study fungal infections .

HY-122943

Moracin D	Natural Products Source classification Morus alba L. Plants Moraceae	Fungal Apoptosis
Moracin D is a flavonoid that can be isolated from Morus alba. Moracin D induces cell apoptosis and shows hypoglycemic, antiadipogenic, antifungal and antitumor effects. Moracin D can be used for fungal infection and breast cancer research .

HY-N7123

Sulfacetamide 3 Publications Verification Sulphacetamide	Infection Classification of Application Fields Disease Research Fields	Antibiotic Bacterial Fungal
Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic. Sulfacetamide has antifungal and antibacterial activities. Sulfacetamide is employed as a topical formulation in various ophthalmic, dermatological, and hair solutions against bacterial infections, acne and scalp conditions. Sulfacetamide targets bacterial folic acid synthesis and is effective against various gram-positive and gram-negative bacteria. Sulfacetamide inhibits the synthesis of both dihydro-folic acid and para-aminobenzoic acid. Sulfacetamide can be used for the study of ocular infections .

HY-N11911

Verazine (-)-Verazine	Alkaloids Other Alkaloids Source classification Veratrum maackii Regel Plants Melanthiaceae	Fungal
Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases .

HY-N15444

Bullatenone	Terpenoids Sesquiterpenes Source classification Lophomyrtus bullata Burret Myrtaceae Plants	Fungal
Bullatenone is a volatile bioactive compound that can be found in Lophomyrtus bullata. It has insect - repellent, anti - ulcer, anti - UV, and antifungal activities. Bullatenone can inhibit the growth of fungi such as Candida albicans and Cladosporium resinae. Bullatenone can be used in the research of diseases such as inflammation and infections .

HY-N15309

Torvoside C Torvoside K	Polysaccharides Source classification Solanum torvum Swartz Solanaceae Plants Saccharides	Fungal
Torvoside C (Torvoside K) is a compound found in Solanum torvum with antifungal activity. The ZOIs and MIC values of Torvoside C against the tested fungi (Alternaria brassicicola, Alternaria geophila, Aspergillus flavus, etc.) range from 33.4% to 87.4% and 31.25 to 250 μg/mL, respectively. Additionally, it exhibits a dose-dependent inhibitory effect on the production of mycotoxins aflatoxin B1 and fumonisin B1, which are produced by A. flavus and F. verticillioides, respectively. Torvoside C can be used for research in the field of antifungal infection .

HY-N7701C

L-Pentaguluronic acid	Infection Classification of Application Fields Disease Research Fields	Others
L-Pentaguluronic acid is a linear polysaccharide copolymer composed of four L-guluronic acid (G) .

HY-N7701

L-Diguluronic acid	Infection Polysaccharides other families Classification of Application Fields Source classification Plants Disease Research Fields Saccharides	Fungal
L-Diguluronic acid is a linear polysaccharide copolymer composed of two L-guluronic acid (G) and can be used to from Alginate . Alginate is a generic name of unbranched polyanionic polysaccharides and can be used for the research of antifungal agents delivery carries .

HY-N7701D

L-Hexaguluronic acid	Infection Classification of Application Fields Disease Research Fields	Others
L-Hexaguluronic acid is a linear polysaccharide copolymer composed of six L-guluronic acid (G) .

HY-N15453

Asperenone	Natural Products Microorganisms Source classification	Lipoxygenase Fungal
Asperenone is an inhibitor of 15-lipoxygenase (15-LOX) with an IC₅₀ value of 0.3 mM. It is also an inhibitor of platelet aggregation, with an IC₅₀ value of 0.23 mM. Additionally, Asperenone has antifungal activity and can inhibit the growth of pathogenic fungi Ophiostoma crassivaginatum and O. piliferum. Asperenone can be used in the research of cardiovascular diseases and anti-infection fields .

HY-N12497

Moracin B	Source classification Phenols Polyphenols Morus alba L. Plants Moraceae	Fungal
Moracin B is a phytoalexin with antifungal activity. Moracin B can be isolated from the cortex and phloem tissues of mulberry (Morus alba Linne) infected with Fusarium solani f. sp. mori. Moracin B can be used to study plant disease resistance mechanisms against microbial infections, particularly showing potential application value in the field of plant disease control .

HY-N8540

Ilicicolin H	Natural Products Microorganisms Source classification	Phosphoglycerate Kinase (PGK) Fungal Apoptosis
Ilicicolin H is a selective and non-ATP-competitive phosphoglycerate kinase 1 (PGK1) (IC₅₀ = 9.02 μM) and mitochondrial cytochrome bc1 reductase (IC₅₀ = 2-3 ng/mL) inhibitor. Ilicicolin H directly binds to PGK1 with K_D of 60 μM .Ilicicolin H can inhibit cell proliferation and induce apoptosis. Ilicicolin H can inhibit the lactate production and glucose uptake of hepatocellular carcinoma (HCC) cells. Ilicicolin H has a broad antifungal spectrum including C. albicans, Cryptococcus and A. fumigatus. Ilicicolin H can be used for the researches of cancer and infection, such as hepatocellular carcinoma (HCC) and C. albicans infection .

HY-N3187

Nimbin	Other Terpenoids Infection other families Neurological Disease Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields	Flavivirus Dengue Virus Fungal Bacterial Histamine Receptor
Nimbin is an orally active intermediate limonoid found in Azadirachta. Nimbin prevents tau aggregation and increases cell viability. Nimbin is effective inhibits the envelope protein of dengue virus. Nimbin has anti-inflammatory, antipyretic, antifungal, antihistamine, antiseptic, antioxidant, anti-cancer and anti-viral properties. Nimbin can across blood-brain barrier. Nimbin is promising for research of neurodegenerative diseases and viral infections .

HY-N7236

Pervicoside B	Triterpenes Animals Terpenoids Source classification	Parasite Fungal
Pervicoside B is a glycoside C isolated from Neothyone gibbosa sea cucumber. In vitro studies have shown that Pervicoside B has a potent antiparasitic effect against Leishmania mexicana, inhibiting 100% of promastigotes at 5-10 μg/mL. Pervicoside B also exhibits strong antifungal activity against Aspergillus niger, with MIC values ranging from 4.65 to 16.7 μg/mL. Pervicoside B has potential applications in the inhibition of parasitic infections and fungal diseases .

HY-B0914

10-Undecenoic acid,98% (stabilized with TBC) 2 Publications Verification Undecylenic acid	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Fungal Amyloid-β Reactive Oxygen Species (ROS) Proteasome Bacterial
10-Undecenoic acid (Undecylenic acid) is an *antifungal* agent. 10-Undecenoic acid inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid has neuroprotective effects. 10-Undecenoic acid has anticancer effects on a variety of tumors. 10-Undecenoic acid inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .

HY-N5142

α-Terpineol 1 Publications Verification	Infection Other Monoterpenes Microorganisms Saururaceae Classification of Application Fields Terpenoids Source classification Myrtaceae Plants Eucalyptus globulus Labill. Inflammation/Immunology Disease Research Fields	Bacterial Antibiotic NF-κB AMPK Fungal
α-Terpineol (with oral activity) can be found in Eucalyptus globulus Labill. α-Terpineol exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria.α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. In addition, α-Terpineol exhibits antineuropathic and anti-inflammatory activities. α-Terpineol can be utilized in research related to diarrhea, neuropathic pain, infections, and inflammation .

HY-B0914A

10-Undecenoic acid zinc salt 2 Publications Verification Zinc undecylenate	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Fungal Bacterial Amyloid-β Reactive Oxygen Species (ROS) Proteasome
10-Undecenoic acid zinc salt (Undecylenic acid zinc salt) is an *antifungal* agent. 10-Undecenoic acid zinc salt inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid zinc salt has neuroprotective effects. 10-Undecenoic acid zinc salt has anticancer effects on a variety of tumors. 10-Undecenoic acid zinc salt inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid zinc salt inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .

HY-33037

Phenazine-1-carboxylic acid	Infection Alkaloids Microorganisms Classification of Application Fields Other Alkaloids Marine natural products Source classification Disease Research Fields	Fungal
Phenazine-1-carboxylic acid is an antifungal agent. Additionally, Phenazine-1-carboxylic acid exhibits anticancer activity by inducing apoptosis in cancer cells through the regulation of ROS generation. Phenazine-1-carboxylic acid can upregulate the expression of IL-8 and ICAM-1 while inhibiting the release of RANTES and MCP-1, demonstrating its potential immunomodulatory effects. Phenazine-1-carboxylic acid holds significant research value in the areas of anti-infection, anticancer, and immune response modulation .

HY-B0914R

10-Undecenoic acid (Standard) Undecylenic acid (Standard)	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Fungal Amyloid-β Reactive Oxygen Species (ROS) Proteasome Bacterial
10-Undecenoic acid (Standard) is the analytical standard of 10-Undecenoic acid. This product is intended for research and analytical applications. 10-Undecenoic acid (Undecylenic acid) is an *antifungal* agent. 10-Undecenoic acid inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid has neuroprotective effects. 10-Undecenoic acid has anticancer effects on a variety of tumors. 10-Undecenoic acid inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .

HY-N3307

(+)-Medioresinol 1 Publications Verification	Cardiovascular Disease Oleaceae Fraxinus mandshurica Rupr. Neurological Disease Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields	Bacterial Fungal Reactive Oxygen Species (ROS) Apoptosis MMP Interleukin Related PI3K Akt mTOR PPAR PGC-1α Pyroptosis
(+)-Medioresinol is a furofuran-type lignan with antifungal and antibacterial properties. (+)-Medioresinol synergizes with antibiotics to exert antimicrobial and antibiofilm effects. (+)-Medioresinol induces intracellular ROS accumulation and mitochondrial-mediated apoptosis in Candida albicans. (+)-Medioresinol inhibits LPS (HY-D1056)-stimulated IL-12p40 production. (+)-Medioresinol is a PGC-1α activator that protects against endothelial cell pyroptosis in ischemic stroke via the PPARα-GOT1 axis. (+)-Medioresinol can be used in research on *fungal* and bacterial infection, inflammation, and ischemic stroke .

HY-B0914AR

10-Undecenoic acid zinc salt (Standard) Zinc undecylenate (Standard)	Microorganisms Ketones, Aldehydes, Acids Source classification	Reference Standards Fungal Amyloid-β Reactive Oxygen Species (ROS) Proteasome Bacterial
10-Undecenoic acid (zinc salt) (Standard) is the analytical standard of 10-Undecenoic acid (zinc salt). This product is intended for research and analytical applications. 10-Undecenoic acid zinc salt (Undecylenic acid zinc salt) is an *antifungal* agent. 10-Undecenoic acid zinc salt inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid zinc salt has neuroprotective effects. 10-Undecenoic acid zinc salt has anticancer effects on a variety of tumors. 10-Undecenoic acid zinc salt inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid zinc salt inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .

HY-33037R

Phenazine-1-carboxylic acid (Standard)	Alkaloids Microorganisms Other Alkaloids Marine natural products Source classification	Reference Standards Fungal
Phenazine-1-carboxylic acid (Standard) is the analytical standard of Phenazine-1-carboxylic acid. This product is intended for research and analytical applications. Phenazine-1-carboxylic acid is an antifungal agent. Additionally, Phenazine-1-carboxylic acid exhibits anticancer activity by inducing apoptosis in cancer cells through the regulation of ROS generation. Phenazine-1-carboxylic acid can upregulate the expression of IL-8 and ICAM-1 while inhibiting the release of RANTES and MCP-1, demonstrating its potential immunomodulatory effects. Phenazine-1-carboxylic acid holds significant research value in the areas of anti-infection, anticancer, and immune response modulation[1][2][3][4].

Cat. No.	Product Name	Chemical Structure

HY-B1790S

Terconazole-d4
Terconazole-d₄ is the deuterium labeled Terconazole. Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection.

HY-17395S

Terbinafine-d3 hydrochloride

Terbinafine-d₃ hydrochloride is the deuterium labeled Terbinafine hydrochloride. Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a K_i of 30 nM . Terbinafine hydrochloride also antibacterial activity against certain Gram-positive and Gram-negative bacteria .

HY-174394S

CYP51-IN-25
CYP51-IN-25 is a orally active broad spectrum antifungal agent with the MIC₈₀ of 0.00625-0.05 μg/mL. is a CYP51-IN-25 is a deuterated compound with antibiotic properties. CYP51-IN-25 can inhibit the fungal CYP51 enzyme, block ergosterol synthesis, and disrupt cell membrane integrity. CYP51-IN-25 can be used for research on *fungal* infections.

HY-14283S1

Luliconazole-d3
Luliconazole-d₃ (NND 502-d₃) is deuterium labeled Luliconazole. Luliconazole (NND 502)?is a topical antifungal imidazole antibiotic with broad-spectrum and potent antifungal activity. Luliconazole can be used for the research of skin infection, including?dermatophytosis, tinea corporis, tinea pedis?et al .

HY-14283S

Luliconazole-13C7
Luliconazole- ¹³C₇ (NND 502- ¹³C₇) is ¹³C labeled Luliconazole. Luliconazole (NND 502)?is a topical antifungal imidazole antibiotic with broad-spectrum and potent antifungal activity. Luliconazole can be used for the research of skin infection, including?dermatophytosis, tinea corporis, tinea pedis?et al .

HY-N7123S

Sulfacetamide-d4
Sulfacetamide-d₄ (Sulphacetamide-d₄) is the deuterium labeled Sulfacetamide (HY-N7123). Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide has antifungal and antibacterial activities .

HY-N7123S1

Sulfacetamide-13C6
Sulfacetamide- ¹³C₆ (Sulphacetamide ¹³C₆) is the ¹³C₆ labeled Sulfacetamide (HY-N7123). Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide has antifungal and antibacterial activities .

HY-17395AS

Terbinafine-d7
Terbinafine-d₇ is the deuterium labeled Terbinafine. Terbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a K_i of 30 nM . Terbinafine also antibacterial activity against certain Gram-positive and Gram-negative bacteria .

HY-114518S2

Butenafine-d4

Butenafine-d4 (KP363-d4) is the deuterium labeled Butenafine (HY-114518). Butenafine (KP363) is a potent and broad spectrum benzylamine antifungal agent . Butenafine inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation, leading to a deficiency of the fungal cell membranes. Butenafine is effective against dermatophytes infections, such as ?tinea pedis, ?tinea cruris, tinea versicolor .

HY-N5142S1

α-Terpineol-d6

α-Terpineol-d₆ is deuterated labeled α-Terpineol (HY-N5142). α-Terpineol (with oral activity) can be found in Eucalyptus globulus Labill. α-Terpineol exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria.α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. In addition, α-Terpineol exhibits antineuropathic and anti-inflammatory activities. α-Terpineol can be utilized in research related to diarrhea, neuropathic pain, infections, and inflammation .

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