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acyclovir

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143

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Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17422

*Acyclovir* 10+ Cited Publications Aciclovir; Acycloguanosine	HSV Apoptosis Antibiotic Bacterial	Infection Cancer
Acyclovir (Aciclovir) is a potent, orally active antiviral agent. Acyclovir has antiherpetic activity with IC₅₀ values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir induces cell cycle perturbation and apoptosis. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia .

HY-17422R

Acyclovir (Standard) Aciclovir (Standard); Acycloguanosine (Standard)	Reference Standards HSV Apoptosis Antibiotic Bacterial	Infection Cancer
Acyclovir (Standard) is the analytical standard of Acyclovir. This product is intended for research and analytical applications. Acyclovir (Aciclovir) is a potent, orally active antiviral agent. Acyclovir has antiherpetic activity with IC50 values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir induces cell cycle perturbation and apoptosis. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia .

HY-17422S1

Acyclovir-d4 Aciclovir-d₄; Acycloguanosine-d₄	Isotope-Labeled Compounds HSV Bacterial Apoptosis Antibiotic	Infection Cancer
Acyclovir-d₄ is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC₅₀ of 0.85 μM), HSV-2 (IC₅₀ of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination . Acyclovir prevents bacterial infections during induction therapy for acute leukaemia .

HY-137362

N2-Acetyl acyclovir	Drug Intermediate	Infection
N2-Acetyl acyclovir is an Acyclovir prodrug. Acyclovir (Aciclovir) is a potent, orally active antiviral agent .

HY-17422B

Acyclovir monophosphate	HSV Antibiotic	Infection Cancer
Acyclovir monophosphate is a potent anti-herpes simplex virus (HSV) agent. Acyclovir monophosphate blocks DNA synthesis through the inhibition of the viral DNA polymerase and terminates the chain elongation of the viral DNA. Acyclovir monophosphate shows antitumor activity .

HY-142028A

Acyclovir triphosphate sodium AcycloGTP sodium	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog HIV Reverse Transcriptase	Infection
Acyclovir triphosphate (Synonyms: AcycloGTP) sodium is a Acyclovir (HY-17422) derivative that competitively inhibits viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). Acyclovir triphosphate sodium is an inhibitor of HIV-1 reverse transcriptase. Acyclovir triphosphate sodium causes termination of viral DNA synthesis .

HY-17422A

Acyclovir sodium Aciclovir sodium; Acycloguanosine sodium	HSV Apoptosis Antibiotic Bacterial	Infection Cancer
Acyclovir (Aciclovir) sodium is a potent, orally active antiviral agent. Acyclovir sodium has antiherpetic activity with IC₅₀ values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir sodium induces cell cycle perturbation and apoptosis. Acyclovir sodium prevents bacterial infections during induction therapy for acute leukaemia .

HY-17422D

Acyclovir hydrochloride Aciclovir hydrochloride; Acycloguanosine hydrochloride	HSV Apoptosis Antibiotic Bacterial	Infection Cancer
Acyclovir (Aciclovir) hydrochloride is a potent, orally active antiviral agent. Acyclovir hydrochloride has antiherpetic activity with IC₅₀ values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir hydrochloride induces cell cycle perturbation and apoptosis. Acyclovir hydrochloride prevents bacterial infections during induction therapy for acute leukaemia .

HY-17422C

Acyclovir alaninate Aciclovir alaninate; Acycloguanosine alaninate	HSV	Infection
Acyclovir alaninate (Acyclovir alaninate) is a prodrug of Acyclovir (HY-17422) and can be used in antiviral (HSV) research .

HY-137362R

*N2-Acetyl acyclovir* (Standard)**	Drug Intermediate Reference Standards	Infection
N2-Acetyl acyclovir (Standard) is the analytical standard of N2-Acetyl acyclovir. This product is intended for research and analytical applications. N2-Acetyl acyclovir is an Acyclovir prodrug. Acyclovir (Aciclovir) is a potent, orally active antiviral agent .

HY-106506

Desciclovir BW A515U	HSV Apoptosis Antibiotic Bacterial	Infection
Desciclovir is a potent and orally active proagent of the antiherpetic agent Acyclovir (ACV). Desciclovir is converted to acyclovir in vivo by xanthine oxidase .

HY-106506R

Desciclovir (Standard) BW A515U (Standard)	HSV Apoptosis Antibiotic Bacterial Reference Standards	Infection
Desciclovir (Standard) is the analytical standard of Desciclovir. This product is intended for research and analytical applications. Desciclovir is a potent and orally active proagent of the antiherpetic agent Acyclovir (ACV). Desciclovir is converted to acyclovir in vivo by xanthine oxidase .

HY-17425B

Valacyclovir hydrochloride hydrate Valaciclovir hydrochloride hydrate	HSV Bacterial	Infection Cancer
Valacyclovir hydrochloride hydrate is a potent antiviral agent. Valacyclovir hydrochloride hydrate can be used in the management of herpes simplex, herpes zoster and herpes B. Valacyclovir hydrochloride hydrate can be formulate ocular inserts for the research of ocular herpes. Valacyclovir hydrochloride hydrate is a precursor and can be rapidly converted into acyclovir in vivo .

HY-W127410

Hexanoic anhydride	Biochemical Assay Reagents	Others
Hexanoic anhydride is used as a reactant for the synthesis of acremomannolipin A. For the green synthesis of acyclovir dipivoxil (acyclovir proagent), for the preparation of hexanoyl-modified chitosan nanoparticles, chitosan-based polymer surfactants by N-acylation of chitosan .

HY-106892

BW 348U87 348U87	DNA/RNA Synthesis	Infection
BW 348U87 is an inhibitor for ribonucleotide reductase, which exhibits synergistic effect with Acyclovir (HY-17422), potentiate the antiviral activity of Acyclovir against herpes simplex virus (HSV) in athymic nude mouse model .

HY-B0222

1-Docosanol 1 Publications Verification Behenyl alcohol	HSV	Infection
1-Docosanol (Behenyl alcohol) is a saturated fatty alcohol with reported inhibitory activity against lipid-enveloped viruses, including herpes simplex virus (HSV) .

HY-B0222R

1-Docosanol (Standard) Behenyl alcohol (Standard)	Reference Standards HSV	Infection
1-Docosanol (Standard) is the analytical standard of 1-Docosanol. This product is intended for research and analytical applications. 1-Docosanol (Behenyl alcohol) is a saturated fatty alcohol with reported inhibitory activity against lipid-enveloped viruses, including herpes simplex virus (HSV) .

HY-137181

9-Carboxymethoxymethylguanine	HSV	Infection
9-Carboxymethoxymethylguanine is the main metabolite of Aciclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent .

HY-174429

HSV-1-IN-3	HSV	Infection
HSV-1-IN-3 (Compound A50) is a HSV inhibitor. HSV-1-IN-3 shows good antiviral efficacy against both Acyclovir (HY-17422) -sensitive and -resistant HSV strains .

HY-W770677

9-Carboxymethoxymethylguanine-13C2,15N	Isotope-Labeled Compounds HSV Drug Metabolite	Infection
9-Carboxymethoxymethylguanine- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled 9-Carboxymethoxymethylguanine (HY-137181). 9-Carboxymethoxymethylguanine is the main metabolite of Aciclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent .

HY-P10304

Cyclo(Arg-Pro) Cyclo(Pro-Arg)	Fungal	Others
Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) is an inhibitor for chitinase. Cyclo(Arg-Pro) inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) inhibits the morphological change of Candida albicans from yeast form to filamentous form .

HY-75564

Cyclo(Ala-Gly)	Endogenous Metabolite	Cancer
Cyclo(Ala-Gly), a metabolite of a mangrove endophytic fungus, Penicillium thomi, exhibits cytotoxicity against A549, HepG2 and HT29 cells. The IC₅₀ values range from 9.5 to 18.1 μM .

HY-P3119

Desotamide Desotamide A	Bacterial	Infection
Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces. It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs=16, 12.5, and 32 μg/mL, respectively).

HY-P0023A

Cyclo(-RGDfK) TFA Maximum Cited Publications 22 Publications Verification	Integrin	Cancer
Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the α_vβ₃ integrin, with an IC₅₀ of 0.94 nM . Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface .

HY-P5033

Cyclo(Gly-His)	Bacterial	Cancer
Cyclo(Gly-His) is a liposome-encapsulated cyclic dipeptide with antimicrobial and anticancer activity. Cyclo(Gly-His) has cytotoxicity for HeLa and MCF-7 cell with IC₅₀ values of 1.699 mM and 0.358 mM, respectively. Cyclo(Gly-His) can be used for the research of drug delivery systems .

HY-P10426

cyclo(CLLFVY)	HIF/HIF Prolyl-Hydroxylase VEGFR	Cancer
cyclo(CLLFVY) is an inhibitor for hypoxia inducible factor-1 (HIF-1), with IC₅₀ of 19 μM (in U2OS) and 16 μM (in MCF-7). cyclo(CLLFVY) binds to the PAS-B domain of HIF-1α, inhibits HIF-1 dimerization and transcriptional activity. cyclo(CLLFVY) downregulates the expression of hypoxia response genes, such as VEGF and CAIX, exhibits antitumor against the HIF-1 associated cancers .

HY-P10222

Cyclo(CRLLIF)	HIF/HIF Prolyl-Hydroxylase	Cancer
Cyclo CRLLIF is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2, which disrupts the interaction of both HIF1-α and HIF2-α with HIF1-β, with affinity for HIF1-α and HIF2-α PAS-B domains K_D of 14.5 and 10.2 μM, respectively .

HY-P1934

Cyclo(Phe-Pro) 4 Publications Verification Cyclo(phenylalanylprolyl); A-64863	HCV Bacterial Antibiotic Reactive Oxygen Species (ROS)	Infection
Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) is a quorum-sensing molecule of Vibrio vulnificus that specifically interacts with RIG-I, inhibiting RIG-I polyubiquitination, suppressing IRF-3 activation, and reducing type I interferon production. Cyclo(Phe-Pro) enhances susceptibility to HCV and influenza virus and also alleviates plant aluminum toxicity stress. The mechanism of Cyclo(Phe-Pro) involves the regulation of host immune signaling pathways, bacterial virulence gene expression, and plant antioxidant systems, making it a promising candidate for research in viral infections, bacterial virulence regulation, and agricultural stress resistance .

HY-W836186

Cyclo(Leu-Ala) Cyclo(alanine-leucine)	Bacterial	Others
Cyclo(Leu-Ala) (Cyclo(alanine-leucine)) is an antimicrobial compound isolated from microorganisms and has antimicrobial activity against some plant pathogens together with other compounds.

HY-139425

Cyclo(Pro-Ala)	Biochemical Assay Reagents	Cancer
Cyclo(Pro-Ala) is an anticancer agent that has toxic to cancer cells such as A549, HCT-116, and HepG2 .

HY-107245

Segetalin B 2 Publications Verification	Estrogen Receptor/ERR Sirtuin RUNX	Metabolic Disease
Segetalin B, an orally active cyclopentapeptide found in Vaccaria segetalis, possesses estrogen-like activity. Segetalin B promotes mineralization of ovariectomized rat-derived bone marrow mesenchymal stem cells (BMSCs) in vitro and increases the level of osteocalcin, BMP-2, ALP, and SIRT1 activity. Segetalin B is promising for research of post-menopausal osteoporosis (PMOP) .

HY-P6294

Pseudostellarin G	Tyrosinase	Others
Pseudostellarin G is a natural cyclic octapeptide. Pseudostellarin G has the activity of inhibiting tyrosinase. Pseudostellarin G can inhibit the production of melanin .

HY-126810A

NP213 TFA	Fungal	Infection
NP213 TFA is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has anti-fungal activities. NP213 TFA targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 TFA is effective and well-tolerated in resolving nail fungal infections .

HY-P5698

Cyclopetide 1	Bacterial	Infection
Cyclopetide 1 (Compound 1) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 25 μg/mL .

HY-P1938

Cyclo(L-Pro-L-Val)	Bacterial	Infection Inflammation/Immunology
Cyclo(L-Pro-L-Val) is an antimicrobial and anti-inflammatory agent. Cyclo(L-Pro-L-Val) has toxic activity against plant pathogens such as R. fascians LMG 3605, and its potency may be comparable to that of Chloramphenicol (HY-B0239). Cyclo(L-Pro-L-Val) can inhibit the phosphorylation of IKKα, IKKβ, NF-κB, etc., and the activation of iNOS and COX-2, thereby exerting anti-inflammatory activity. Cyclo(L-Pro-L-Val) can be used in the research of biopesticides in the agricultural field, as well as in the research of inflammation-related diseases .

HY-100563A

Cyclo(RGDyK) 4 Publications Verification	Integrin	Cancer
Cyclo(RGDyK) is a potent and selective α_Vβ₃ integrin inhibitor with an IC₅₀ of 20 nM.

HY-P0231

AZP-531 2 Publications Verification	GHSR	Metabolic Disease Endocrinology
AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.

HY-P1934A

Cyclo(L-Phe-L-Pro)	Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology Cancer
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-101402A

Cyclo(his-pro) TFA Cyclo(histidyl-proline) TFA; Histidylproline diketopiperazine TFA	NF-κB Endogenous Metabolite	Neurological Disease Inflammation/Immunology
Cyclo(his-pro) TFA (Cyclo(histidyl-proline) TFA) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) TFA could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) TFA can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .

HY-P2092

Cyclo(L-leucyl-L-tryptophyl) Cyclo(Leu-Trp)	Bacterial Fungal Melatonin Receptor	Infection Neurological Disease
Cyclo(L-leucyl-L-tryptophyl) (Cyclo(-Leu-Trp)) is a cyclic dipeptide that inhibits a various of bacteria and fungi. Cyclo(L-leucyl-L-tryptophyl) is a melatonin receptor agonist and is also used as a bitter ligand .

HY-101402

Cyclo(his-pro) Cyclo(histidyl-proline); Histidylproline diketopiperazine	NF-κB Endogenous Metabolite	Neurological Disease Inflammation/Immunology
Cyclo(his-pro) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .

HY-P5314

OK2	EGFR STAT	Others
OK2, a specific inhibitor of the CCN2/EGFR interaction, efficiently blocks CCN2/EGFR interaction through binding to the CT domain of CCN2. OK2 can be used for kidney fibrosis and chronic kidney disease research .

HY-P10052

CBO-P11	VEGFR	Cancer
CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. CBO-P11 is modified with a nearinfrared cyanine dye bearing an alkyne function, allowing both “click” coupling on azido-modified nanoparticles and fluorescence labelling .

HY-P3472

Cyclo(IP) Cyclo(L-Pro-L-Ile)	Amino Acid Derivatives	Inflammation/Immunology
Cyclo(IP) (Cyclo-(L-Pro-L-Ile)), a Diketopiperazine can be derived From Bacillus thuringiensis JCK-1233, results in suppression of PWD severity and increased the expression of defense-related genes similarly to Bacillus thuringiensis JCK-1233 treatment .

HY-P1935

Cyclo(Ala-Pro)	Biochemical Assay Reagents	Cancer
Cyclo(Ala-Pro) is an anticancer agent that is toxic to cancer cells such as A549, HCT-116 and HepG2 .

HY-P0023

Cyclo(-RGDfK) Maximum Cited Publications 22 Publications Verification	Integrin	Cancer
Cyclo(-RGDfK) is a potent and selective inhibitor of the α_vβ₃ integrin, with an IC₅₀ of 0.94 nM . Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface .

HY-P6293

Heterophyllin A	Cathepsin	Others
Heterophyllin A can be isolated from the aboveground parts of Elaeagnus angustifolia.

HY-169684

Vaccarin C	Fungal	Infection Cancer
Vaccarin C (Compound VIII) is a cycloheptapeptide with good antifungal activity against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes with MIC values of 6 µg/mL. Vaccarin C also has high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines with IC₅₀ values of 3.35 and 5.72 μM, respectively .

HY-P10221A

Cyclo(CKLIIF) TFA	HIF/HIF Prolyl-Hydroxylase	Cancer
Cyclo CKLIIF is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2, which disrupts the interaction of both HIF1-α and HIF2-α with HIF1-β, with affinity for HIF1-α and HIF2-α PAS-B domains K_D of 2.6 and 2.2 μM, respectively .

HY-126810

NP213	Fungal	Infection
NP213 is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has anti-fungal activities. NP213 targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 is effective and well-tolerated in resolving nail fungal infections .

Cat. No.	Product Name	Type

HY-142028A

Acyclovir triphosphate sodium AcycloGTP sodium	Gene Sequencing and Synthesis
Acyclovir triphosphate (Synonyms: AcycloGTP) sodium is a Acyclovir (HY-17422) derivative that competitively inhibits viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). Acyclovir triphosphate sodium is an inhibitor of HIV-1 reverse transcriptase. Acyclovir triphosphate sodium causes termination of viral DNA synthesis .

HY-W127410

Hexanoic anhydride	Biochemical Assay Reagents
Hexanoic anhydride is used as a reactant for the synthesis of acremomannolipin A. For the green synthesis of acyclovir dipivoxil (acyclovir proagent), for the preparation of hexanoyl-modified chitosan nanoparticles, chitosan-based polymer surfactants by N-acylation of chitosan .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0222

1-Docosanol 1 Publications Verification Behenyl alcohol	Infection Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields	HSV
1-Docosanol (Behenyl alcohol) is a saturated fatty alcohol with reported inhibitory activity against lipid-enveloped viruses, including herpes simplex virus (HSV) .

HY-75564

Cyclo(Ala-Gly)	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
Cyclo(Ala-Gly), a metabolite of a mangrove endophytic fungus, Penicillium thomi, exhibits cytotoxicity against A549, HepG2 and HT29 cells. The IC₅₀ values range from 9.5 to 18.1 μM .

HY-131115

Cyclo(Tyr-Leu)	Natural Products Portulacaceae Classification of Application Fields Source classification Other Diseases Portulaca oleracea Linn. Plants Disease Research Fields	Others
Cyclo(Tyr-Leu) is a cyclic dipeptide .

HY-107245

Segetalin B 2 Publications Verification	Structural Classification Vaccaria segetalis (Neck.) Garcke Classification of Application Fields Cyclopeptides Source classification Metabolic Disease Plants Disease Research Fields Caryophyllaceae	Estrogen Receptor/ERR Sirtuin RUNX
Segetalin B, an orally active cyclopentapeptide found in Vaccaria segetalis, possesses estrogen-like activity. Segetalin B promotes mineralization of ovariectomized rat-derived bone marrow mesenchymal stem cells (BMSCs) in vitro and increases the level of osteocalcin, BMP-2, ALP, and SIRT1 activity. Segetalin B is promising for research of post-menopausal osteoporosis (PMOP) .

HY-P1936

Cyclo(Gly-L-Pro)	Structural Classification Alkaloids Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Source classification Plants Araliaceae	Others
Cyclo(Gly-L-Pro) is a Alkaloids product that can be isolated from the roots of Panax notoginseng (Burk.)F.H.Chen .

HY-P1938

Cyclo(L-Pro-L-Val)	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Cyclo(L-Pro-L-Val) is an antimicrobial and anti-inflammatory agent. Cyclo(L-Pro-L-Val) has toxic activity against plant pathogens such as R. fascians LMG 3605, and its potency may be comparable to that of Chloramphenicol (HY-B0239). Cyclo(L-Pro-L-Val) can inhibit the phosphorylation of IKKα, IKKβ, NF-κB, etc., and the activation of iNOS and COX-2, thereby exerting anti-inflammatory activity. Cyclo(L-Pro-L-Val) can be used in the research of biopesticides in the agricultural field, as well as in the research of inflammation-related diseases .

HY-B0222R

1-Docosanol (Standard) Behenyl alcohol (Standard)	Structural Classification Natural Products other families Source classification Plants	Reference Standards HSV
1-Docosanol (Standard) is the analytical standard of 1-Docosanol. This product is intended for research and analytical applications. 1-Docosanol (Behenyl alcohol) is a saturated fatty alcohol with reported inhibitory activity against lipid-enveloped viruses, including herpes simplex virus (HSV) .

HY-P5751

Cyclo(Ile-Val)	Structural Classification Alkaloids Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Other Alkaloids Source classification Plants Araliaceae	Others
Cyclo(Ile-Val) is a Alkaloids product that can be isolated from the roots of Panax notoginseng (Burk.)F.H.Chen .

HY-P6294

Pseudostellarin G	Structural Classification Natural Products Pseudostellaria heterophylla (Miq.) Pax Source classification Plants Caryophyllaceae	Tyrosinase
Pseudostellarin G is a natural cyclic octapeptide. Pseudostellarin G has the activity of inhibiting tyrosinase. Pseudostellarin G can inhibit the production of melanin .

HY-P5698

Cyclopetide 1	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Cyclopetide 1 (Compound 1) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 25 μg/mL .

HY-P1934A

Cyclo(L-Phe-L-Pro)	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields Cancer	Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-101402A

Cyclo(his-pro) TFA Cyclo(histidyl-proline) TFA; Histidylproline diketopiperazine TFA	Structural Classification Natural Products Source classification Endogenous metabolite	NF-κB Endogenous Metabolite
Cyclo(his-pro) TFA (Cyclo(histidyl-proline) TFA) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) TFA could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) TFA can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .

HY-101402

Cyclo(his-pro) Cyclo(histidyl-proline); Histidylproline diketopiperazine	Structural Classification Natural Products Source classification Endogenous metabolite	NF-κB Endogenous Metabolite
Cyclo(his-pro) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .

HY-N9251

Cyclo(Ile-Ala)	Alkaloids Structural Classification Microorganisms Classification of Application Fields Other Alkaloids Marine natural products Source classification Other Diseases Marine microorganism Disease Research Fields	Others
Cyclo(Ile-Ala) is found in marine actinomycete 11014 I. .

HY-P1935

Cyclo(Ala-Pro)	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Biochemical Assay Reagents
Cyclo(Ala-Pro) is an anticancer agent that is toxic to cancer cells such as A549, HCT-116 and HepG2 .

HY-P6293

Heterophyllin A	Structural Classification Natural Products Pseudostellaria heterophylla (Miq.) Pax Source classification Plants Caryophyllaceae	Cathepsin
Heterophyllin A can be isolated from the aboveground parts of Elaeagnus angustifolia.

HY-N13127

Segetalin C	Structural Classification Natural Products Source classification Plants Vaccaria hispanica Caryophyllaceae	Others
Segetalin C is a cyclic peptide that increases uterine weight in ovariectomized rats (2.5 mg/kg).

HY-N11955

Cyclo(Ile-Leu)	Structural Classification Alkaloids Microorganisms Other Alkaloids Marine natural products Source classification Endogenous metabolite	Others
Cyclo(Ile-Leu) is a Alkaloids product that can be isolated from From Penicillium oxalicum .

HY-P5699

Cyclopetide 2	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Cyclopetide 2 (Compound 2) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 50 μg/mL .

HY-P1680

Astin C Asterin	Structural Classification Natural Products Source classification Plants Compositae Erythrina latissima E. Mey.	STING HSV
Astin C (Asterin) is a cyclopeptide that can be extracted from Aster tataricus. Astin C has anti-inflammatory and anti-cancer activities. Astin C can specifically inhibit the cGAS-STING signaling pathway, block the recruitment of IRF3 to the STING signalosome, and thus inhibit the innate inflammatory response. Astin C can be used in the research of autoimmune diseases and cancers .

HY-P2040

Nodularin	Structural Classification other families Cyclopeptides Ketones, Aldehydes, Acids Marine natural products Source classification Plants	Phosphatase
Nodularin is a potent hepatotoxin, tumor promoter, and protein phosphatase inhibitor .

HY-W019721

Cyclosporin D	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Nuclear Factor of activated T Cells (NFAT)
Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A . Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) .

HY-P2005

Malformin C	Structural Classification Natural Products Microorganisms Source classification	Reactive Oxygen Species (ROS) SOD
Malformin C is an algicidal peptide can be isolated from Aspergillus and exhibits dose-dependent algicidal activity. Malformin C induces a significant increase in ROS levels in algal cells, resulting in impaired SOD activity and high production of MDA content .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-P5957

Omphalotin A	Structural Classification Microorganisms Cyclopeptides Source classification	Parasite
Omphalotin A is a cyclic peptide, and shows nematicidal activity .

Cat. No.	Product Name	Chemical Structure

HY-17422S1

Acyclovir-d4

Acyclovir-d₄ is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC₅₀ of 0.85 μM), HSV-2 (IC₅₀ of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination . Acyclovir prevents bacterial infections during induction therapy for acute leukaemia .

HY-W770677

9-Carboxymethoxymethylguanine-13C2,15N
9-Carboxymethoxymethylguanine- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled 9-Carboxymethoxymethylguanine (HY-137181). 9-Carboxymethoxymethylguanine is the main metabolite of Aciclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent .

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