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HeV

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By Targets:	Hepatitis E Virus (HEV) (3) Filovirus (2) PI4K (1) SARS-CoV (2)
By Research Areas:	Infection (5)

5

Inhibitors & Agonists

1

Natural
Products

13

Recombinant Proteins

Targets Recommended: Hepatitis E Virus (HEV) Enterovirus

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

T-00127_HEV1 3 Publications Verification	PI4K	Infection
T-00127_HEV1 is a phosphatidylinositol 4-kinase III beta (PI4KB) inhibitor with an IC₅₀ of 60 nM.

SCR007	SARS-CoV Hepatitis E Virus (HEV) Filovirus	Infection
SCR007 is a synthetic carbohydrate receptor (SCR) with broad-spectrum antiviral activity. SCR007 inhibits the entry of enveloped viruses across multiple families (Coronaviridae: SARS-CoV-1, SARS-CoV-2, MERS-CoV; Filoviridae: EBOV, MARV; Paramyxoviridae: NiV, HeV) and the glycosylated nonenveloped rotavirus. SCR007 binds viral envelope N-glycans, blocking viral binding to host cells or both binding and membrane fusion. SCR007 exerts prophylactic effects in hACE2 mice infected with SARS-CoV-2. SCR007 can be used for the study and prevention of enveloped virus pandemics .

SCR005	SARS-CoV Filovirus Hepatitis E Virus (HEV)	Infection
SCR005 is a synthetic carbohydrate receptor (SCR) with broad-spectrum antiviral activity. SCR005 inhibits the entry of enveloped viruses across multiple families (Coronaviridae: SARS-CoV-1, SARS-CoV-2, MERS-CoV; Filoviridae: EBOV, MARV; Paramyxoviridae: NiV, HeV) and the glycosylated nonenveloped rotavirus. SCR005 binds viral envelope N-glycans, blocking viral binding to host cells or both binding and membrane fusion. SCR005 exerts prophylactic effects in hACE2 mice infected with SARS-CoV-2. SCR005 can be used for the study and prevention of enveloped virus pandemics .

(±)-Nirtetralin	Others	Infection
(±)-Nirtetralin is an isomer of Nirtetralin, which inhibits growth of hepatitis E virus (HEV) in HepaRG cells .

Antiviral agent 48	Hepatitis E Virus (HEV)	Infection
Antiviral agent 48 (compound 9m) is a pan-antiviral agent. Antiviral agent 48 has anti-HEV activity and cytotoxicity (EC₉₀=30.6 nM; CC₅₀=13.8 nM) .

Species:	Human (5) Virus (2) Rhesus Macaque (1) Mouse (1) Cynomolgus (3) Canine (1)
Tag:	His (9) Tag Free (3) Avi (1) Fc (1)
Source:	HEK293 (6) E. coli (7)

Cat. No.	Compare	Product Name	Species	Source

	IL-33 Protein, Human 4 Publications Verification rHuIL-33; IL-1F11; NF-HeV; DVS 27	Human	E. coli
	IL-33 Protein, Human, a Th2 cytokine, is a specific ligand for ST2L.

	IL-33 Protein, Canine 1 Publications Verification Interleukin-33; IL-33; IL-1F11; NF-HeV; DVS 27	Canine	E. coli
	IL-33 Protein activates NF-kappa-B and MAPK signaling, inducing Th2 cell maturation and cytokine secretion. It activates mast cells, basophils, eosinophils, and natural killer cells, acting as a chemoattractant for Th2 cells. IL-33 preserves Krebs cycle integrity, reducing reactive oxygen species production. In quiescent endothelial cells, IL-33 acts as a transcriptional repressor, but is lost upon angiogenic or pro-inflammatory activation. IL-33 Protein, Canine is the recombinant canine-derived IL-33 protein, expressed by E. coli , with N-Met labeled tag.

	IL-33 Protein, Cynomolgus Interleukin-33; IL-33; IL-1F11; NF-HeV; DVS 27	Cynomolgus	E. coli
	IL-33 Protein is a cytokine belonging to the IL-1 superfamily. IL-33 induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines. IL-33 acts intracellularly as a nuclear factor and extracellularly as a cytokine. IL-33 mediates its biological effects via IL-1 receptor ST 2, activates NF-kappaB and MAP kinases, and drives production of T(H)2-associated cytokines from in vitro polarized T(H)2 cells. IL-33 Protein, Cynomolgus is the recombinant cynomolgus-derived IL-33 protein, expressed by E. coli , with tag free.

	Hendra virus Glycoprotein/GP Protein (HEK293, Fc) Hendra virus (HeV) (isolate Horse/Autralia/Hendra/1994) Glycoprotein Protein (Fc)	Virus	HEK293
	The Hendra virus Glycoprotein/GP initiates infection by binding the virus to sialic acid-containing cell receptors. Upon binding, GP induces a conformational change, triggering fusion between the virion and cell membranes by the F protein. Hendra virus Glycoprotein/GP Protein (HEK293, Fc) is the recombinant Virus-derived Hendra virus Glycoprotein/GP protein, expressed by HEK293 , with C-hFc labeled tag.

	IL-33 Protein, Rhesus macaque (His) Interleukin-33; IL-33; IL-1F11; NF-HeV; IL33; C9orf26	Rhesus Macaque	E. coli
	IL-33 is a member of the IL-1 family, known for its significant divergence. IL-33 Protein, Rhesus macaque (His) is the recombinant Rhesus Macaque-derived IL-33 protein, expressed by E. coli , with N-6*His labeled tag.

	IL-33 Protein, Cynomolgus (HEK293, His) C9orf26 Z; DVS27; IL1F11; NF-HeV; NFEHeV; IL33; DV27; C9ORF26; RP11-575C20.2	Cynomolgus	HEK293
	The IL-33 protein is part of the IL-1 family, a different cytokine that is critical in immune responses and inflammation. IL-33 acts through its receptor ST2 to promote the activation and recruitment of immune cells such as Th2 cells, mast cells, and eosinophils to sites of inflammation. IL-33 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-33 protein, expressed by HEK293 , with N-His labeled tag.

	IL-33 Protein, Human (HEK293, His) rHuIL-33; IL-1F11; NF-HeV; DVS 27	Human	HEK293
	IL-33 protein, as a cytokine, binds to and signals through the IL1RL1/ST2 receptor, thereby activating the NF-kappa-B and MAPK signaling pathways in target cells. It is involved in the maturation of Th2 cells and contributes to the secretion of T helper cell type 2 related cytokines. IL-33 Protein, Human (HEK293, His) is the recombinant human-derived IL-33 protein, expressed by HEK293, with N-His labeled tag.

	Hendra virus Glycoprotein/GP Protein (HEK293, His) Hendra virus (HeV) (isolate Horse/Autralia/Hendra/1994) Glycoprotein Protein (Fc)	Virus	HEK293
	The Hendra virus Glycoprotein/GP initiates infection by binding the virus to sialic acid-containing cell receptors. Upon binding, GP induces a conformational change, triggering fusion between the virion and cell membranes by the F protein. Hendra virus Glycoprotein/GP Protein (HEK293, His) is the recombinant virus-derived Hendra virus Glycoprotein/GP protein, expressed by HEK293, with N-His labeled tag.

	IL-33 Protein, Human (C208S, C227S, C232S, C259S, HEK293, His ) rHuIL-33; IL-1F11; NF-HeV; DVS 27	Human	HEK293
	IL-33 protein, as a cytokine, binds to and signals through the IL1RL1/ST2 receptor, thereby activating the NF-kappa-B and MAPK signaling pathways in target cells. It is involved in the maturation of Th2 cells and contributes to the secretion of T helper cell type 2 related cytokines. IL-33 Protein, Human (C208S, C227S, C232S, C259S, HEK293, His ) is the recombinant human-derived IL-33 protein, expressed by HEK293, with C-His labeled tag.

	IL-33 Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) C9orf26 Z; DVS27; IL1F11; NF-HeV; NFEHeV; IL33; DV27; C9ORF26; RP11-575C20.2	Cynomolgus	HEK293

	IL-33 Protein, Human (His) 1 Publications Verification Interleukin-33; IL-33; Interleukin-1 Family Member 11; IL-1F11; Nuclear Factor From High Endothelial Venules; NF-HeV; IL33; C9orf26; IL1F11; NFHeV	Human	E. coli
	IL-33 protein, as a cytokine, binds to and signals through the IL1RL1/ST2 receptor, thereby activating the NF-kappa-B and MAPK signaling pathways in target cells. It is involved in the maturation of Th2 cells and contributes to the secretion of T helper cell type 2 related cytokines. IL-33 Protein, Human (His) is the recombinant human-derived IL-33 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70475AF

	Animal-Free IL-33 Protein, Human (His) 1 Publications Verification Interleukin-33; IL-33; Interleukin-1 Family Member 11; IL-1F11; Nuclear Factor From High Endothelial Venules; NF-HeV; IL33; C9orf26; IL1F11; NFHeV	Human	E. coli
	IL-33 protein, as a cytokine, binds to and signals through the IL1RL1/ST2 receptor, thereby activating the NF-kappa-B and MAPK signaling pathways in target cells. It is involved in the maturation of Th2 cells and contributes to the secretion of T helper cell type 2 related cytokines. Animal-Free IL-33 Protein, Human (His) is the recombinant human-derived animal-FreeIL-33 protein, expressed by E. coli , with C-His labeled tag.This product is for cell culture use only.

HY-P700208AF

	Animal-Free IL-33 Protein, Mouse (His) Interleukin-33; IL-33; Interleukin-1 FamILy Member 11; IL-1F11; Nuclear Factor From High Endothelial Venules; NF-HeV; IL33; C9orf26; IL1F11; NFHeV	Mouse	E. coli
	IL-33 protein activates NF-kappa-B and MAPK signaling, inducing Th2 cell maturation and cytokine secretion. It activates mast cells, basophils, eosinophils, and natural killer cells and enhances macrophage polarization. Animal-Free IL-33 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-33 protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

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