2. Recombinant Proteins
  3. Viral Proteins
  4. Hendra virus Glycoprotein/GP Protein (HEK293, His)

Hendra virus Glycoprotein/GP Protein (HEK293, His)

Cat. No.: HY-P704656
Handling Instructions Technical Support

The Hendra virus Glycoprotein/GP initiates infection by binding the virus to sialic acid-containing cell receptors. Upon binding, GP induces a conformational change, triggering fusion between the virion and cell membranes by the F protein. Hendra virus Glycoprotein/GP Protein (HEK293, His) is the recombinant virus-derived Hendra virus Glycoprotein/GP protein, expressed by HEK293, with N-His labeled tag.

For research use only. We do not sell to patients.

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Description

The Hendra virus Glycoprotein/GP initiates infection by binding the virus to sialic acid-containing cell receptors. Upon binding, GP induces a conformational change, triggering fusion between the virion and cell membranes by the F protein. Hendra virus Glycoprotein/GP Protein (HEK293, His) is the recombinant virus-derived Hendra virus Glycoprotein/GP protein, expressed by HEK293, with N-His labeled tag.
Background

The Hendra virus Glycoprotein/GP plays a pivotal role in initiating infection by attaching the virus to sialic acid-containing cell receptors. Upon binding to the receptor, glycoprotein G induces a conformational change that facilitates the triggering of fusion between virion and cell membranes by the F protein.
Species

Virus
Source

HEK293
Tag

N-His
Accession

O89343 (Q71-S604)
Gene ID

1446471
Molecular Construction
N-term
His
HeV GP (Q71-S604)
Accession # O89343
C-term
Synonyms
Hendra virus (HeV) (isolate Horse/Autralia/Hendra/1994) Glycoprotein Protein (Fc)
Predicted Molecular Mass
61.5 kDa.
Molecular Weight

Approximately 80-100 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Glycosylation
Yes
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

Hendra virus Glycoprotein/GP Protein (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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