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Results for "

GH

" in MedChemExpress (MCE) Product Catalog:

65

Inhibitors & Agonists

2

Fluorescent Dye

1

Biochemical Assay Reagents

22

Peptides

2

Inhibitory Antibodies

16

Recombinant Proteins

5

Antibodies

7

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1515

    Neurodye GH1-84

    Fluorescent Dye Neurological Disease
    FM1-84 (Neurodye GH1-84) is a fluorescent dye. FM1-84 has lipophilic and facilitates association with membranes, resulting in an increase in fluorescence intensity (λex=510 nm, λem=625 nm). FM1-84 can be used for synaptic vesicle recycling in neurons research .
    FM1-84
  • HY-D1599

    R6GH

    Fluorescent Dye Others
    Rhodamine 6G hydrazide (R6GH) is a fluorescent dye. Rhodamine 6G hydrazide can be used in selective colorimetric and fluorescent sensing .
    Rhodamine 6G hydrazide
  • HY-RS24406

    Small Interfering RNA (siRNA) Others

    Gh1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gh1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Gh1 Rat Pre-designed siRNA Set A
    Gh1 Rat Pre-designed siRNA Set A
  • HY-RS05408

    Small Interfering RNA (siRNA) Others

    GH1 Human Pre-designed siRNA Set A contains three designed siRNAs for GH1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GH1 Human Pre-designed siRNA Set A
    GH1 Human Pre-designed siRNA Set A
  • HY-RS05409

    Small Interfering RNA (siRNA) Others

    GH2 Human Pre-designed siRNA Set A contains three designed siRNAs for GH2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GH2 Human Pre-designed siRNA Set A
    GH2 Human Pre-designed siRNA Set A
  • HY-W774937

    GH414; NK-8116

    Insecticide Others
    Cycloprothrin (GH414; NK-8116) is an insecticide pesticide that contains two isomers, (1R, alphaR)-Cycloprothrin and (R)-Cycloprothrin. The insecticidal activity of (1R, alphaR)-Cycloprothrin against Mythimaseparata and Aphismedicagini larvae is about 6 times and 4 times higher than that of (R)-Cycloprothrin, respectively .
    Cycloprothrin
  • HY-P3056

    GHSR Endocrinology
    GHRF, ovine is a growth hormone-releasing factor. GHRF is a specific mediator for the effects of hypoglycemia upon the release of pituitary growth hormone (GH) .
    GHRF, ovine
  • HY-P3607

    bGRF(1-44)-NH2

    GHSR Endocrinology
    GHRF, bovine (bGRF(1-44)-NH2) is the bovine growth hormone (GH)-releasing factor (GHRF). GHRF, bovine increases the release of bovine GH, and shows a synergistic effect with Hydrocortisone (HY-N0583) .
    GHRF, bovine
  • HY-P3595

    GHSR Endocrinology
    GHRF, porcine is a growth hormone releasing factor (GHRF) peptide (porcine). GHRF binds to GHSR and induces the release of growth hormone .
    GHRF, porcine
  • HY-116959

    GHSR Metabolic Disease
    SM-130686 is an oxindole derivative and an active GH secretagogue (GHS). SM-130686 stimulates GH release with a Half-maximum stimulation of 6.3 nM. SM-130686 has an orally active .
    SM-130686
  • HY-14820A

    EP-1572 acetate; AEZS-130 acetate

    GHSR Neurological Disease Endocrinology Cancer
    Macimorelin (EP-1572) acetate, a GH secretagogue, is an orally active GHSR agonist. Macimorelin acetate stimulates GH release. Macimorelin acetate can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS) .
    Macimorelin acetate
  • HY-14820

    EP-1572; AEZS-130

    GHSR Endocrinology Cancer
    Macimorelin (EP-1572), a GH secretagogue, is an orally active GHSR agonist. Macimorelin stimulates GH release. Macimorelin can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS) .
    Macimorelin
  • HY-125673

    Somatostatin Receptor Neurological Disease
    AC-178335 is a SRIF antagonist, with a Ki of 172 nM. AC-178335 blocks SRIF inhibition of adenylate cyclase in vitro (IC50=5.1 μM). AC-178335 induces GH release in anesthetized rats .
    AC-178335
  • HY-50760

    GHSR Endocrinology
    L-692585 is a potent and nonpeptidyl growth hormone secretagogue receptor (GHS-R1a) agonist, with a Ki of 0.8 nM. L-692585 acts directly on somatotropes causing GH release .
    L-692585
  • HY-P0024

    DG3173; PTR-3173

    Somatostatin Receptor Endocrinology Cancer
    Veldoreotide (DG3173) a somatostatin analogue, binds to and activate the somatostatin receptors (SSTR) 2, 4, and 5. Veldoreotide inhibits growth hormone (GH) secretion in adenomas compared with Octreotide (HY-P0036). Veldoreotide has the potential to be used as pain modulating agent
    Veldoreotide
  • HY-P1777

    Insulin-like Growth Factor I (24-41)

    IGF-1R Metabolic Disease Inflammation/Immunology
    IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development .
    IGF-I (24-41)
  • HY-P1777A

    Insulin-like Growth Factor I (24-41) (TFA)

    IGF-1R Metabolic Disease Inflammation/Immunology
    IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) TFA is amino acids 24 to 41 fragment of IGF-I. IGF-I TFA, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I TFA is partly responsible for systemic growth hormone (GH) activities. IGF-I TFA has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) TFA regulates somatic growth and behavioral development .
    IGF-I (24-41) (TFA)
  • HY-108905

    Human IGF-I; FK 780

    IGF-1R Metabolic Disease
    Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies .
    Mecasermin
  • HY-W011410

    p-Nitrophenyl β-D-Mannopyranoside

    Glycosidase Others
    4-Nitrophenyl β-D-mannopyranoside is a useful substrate for β-D-mannopyranosidase. 4-Nitrophenyl β-D-mannopyranoside is also a substrate for GH1-glucosidase (EaBgl1A) and α-L-rhamnosidase .
    4-Nitrophenyl β-D-mannopyranoside
  • HY-P1139

    PCFWKTCK

    GHSR Metabolic Disease
    Cortistatin-8 (CST-8; PCFWKTCK), a neuropeptide, is a GHS-R1a antagonist by counteracting the response of ghrelin on gastric acid secretion. Cortistatin-8 can modulate GH release from somatotroph cells. Cortistatin-8 is a synthetic CST-analogue devoid of any binding affinity to SST-R but capable to bind the GHS-R1a. Cortistatin-8 can exert antagonistic effects on ghrelin actions either in vitro or in vivo in animals .
    Cortistatin-8
  • HY-P1155
    GRF (1-29) amide (rat)
    1 Publications Verification

    rGHRH(1-29)NH2

    GHSR Cancer
    GRF (1-29) amide (rat) is a synthetic peptide which can stimulate the growth hormone (GH) secretion.
    GRF (1-29) amide (rat)
  • HY-RS05399

    Small Interfering RNA (siRNA) Others

    GGH Human Pre-designed siRNA Set A contains three designed siRNAs for GGH gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GGH Human Pre-designed siRNA Set A
    GGH Human Pre-designed siRNA Set A
  • HY-E70107

    Cbh1

    Others Others
    Cellobiohydrolase I (Cbh1) belongs to glycoside hydrolase family 7 (GH7) that catalyzes the processive hydrolysis of cellulose into cellobiose .
    Cellobiohydrolase I
  • HY-121580

    NN703

    Cytochrome P450 Endocrinology
    Tabimorelin (NN703) is an orally active growth hormone (GH) secretagogue. Tabimorelin is also a potent inhibitor of CYP3A4 activity .
    Tabimorelin
  • HY-10199A
    Ibutamoren
    5 Publications Verification

    MK-677 free base; MK-0677 free base

    GHSR Metabolic Disease
    Ibutamoren (MK-677) is an orally active growth hormone secretagogue receptor (GHSR) agonist and a nonpeptide growth hormone secretagogue. Ibutamoren can be used for metabolic research .
    Ibutamoren
  • HY-103540

    NN703 hemifumarate

    Cytochrome P450 Endocrinology
    Tabimorelin (NN703) hemifumarate is an orally active growth hormone (GH) secretagogue. Tabimorelin hemifumarate is also a potent inhibitor of CYP3A4 activity .
    Tabimorelin hemifumarate
  • HY-50844
    Ibutamoren Mesylate
    5 Publications Verification

    MK-677; MK-0677

    GHSR Endocrinology
    Ibutamoren Mesylate (MK-677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist. Ibutamoren Mesylate is an orally active growth hormone (GH) secretagogue.
    Ibutamoren Mesylate
  • HY-139431

    OGA Bacterial Infection
    NAG-thiazoline is a O-GlcNAcase inhibitor with a Ki of 180 nM. NAG-thiazoline is a potent GH20 GlcNAcase (VhGlcNAcase) inhibitor with an IC50 of 11.9 μM and a Ki of 62 µM .
    NAG-thiazoline
  • HY-117584

    GHSR Endocrinology
    L-163255 free base is an orally active spiropiperidine GH secretagogue. L-163255 (free base) can also increase plasma IGF-I level .
    L-163255 free base
  • HY-P0089

    Growth Hormone Releasing Factor human; Somatorelin (1-44) amide (human)

    GHSR Endocrinology
    Human growth hormone-releasing factor (Growth Hormone Releasing Factor human) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary .
    Human growth hormone-releasing factor
  • HY-119997

    CH 29-717

    Dopamine Receptor Neurological Disease Endocrinology
    Disulergine (CH 29-717) is an ergot alkaloid. Disulergine is a dopamine receptor agonist. Disulergine inhibits secretion of prolactin in rats. Disulergine inhibits growth hormone (GH) release .
    Disulergine
  • HY-P0089A

    Growth Hormone Releasing Factor human TFA; Somatorelin (1-44) amide (human) (TFA)

    GHSR Endocrinology
    Human growth hormone-releasing factor TFA (Growth Hormone Releasing Factor human TFA) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary .
    Human growth hormone-releasing factor TFA
  • HY-P99900

    MSL-109

    CMV Infection
    Sevirumab (MSL-109) is a human IgG1 neutralizing monoclonal antibody against cytomegalovirus (CMV). Sevirumab recognizes CMV gH complexes and inhibits CMV replication with an EC50 of 0.3 μg/mL .
    Sevirumab
  • HY-P5189A

    Endogenous Metabolite Cholinesterase (ChE) Others
    His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels .
    His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA
  • HY-P4405

    GHSR Endocrinology
    (D-Ala2)-GRF (1-29) amide (human) is a superagonist of GRF, exhibiting extremely high GH-releasing activity about 50 times that of GRF (1-29) in both pigs and rats .
    (D-Ala2)-GRF (1-29) amide (human)
  • HY-147666

    α-synuclein Neurological Disease
    α-Synuclein inhibitor 4 (compound 3gh) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 0.98 μM and inhibition ratio at 30 μM of 91.2% .
    α-Synuclein inhibitor 4
  • HY-P3169

    CRFR Inflammation/Immunology
    α-Helical Corticotropin Releasing Factor (9-41) is a corticotropin releasing factor (CRF) antagonist. α-Helical Corticotropin Releasing Factor (9-41) decreases plasma growth hormone (GH) values in vivo .
    a-Helical Corticotropin Releasing Factor (9-41)
  • HY-E70316

    Endo-chitosanase

    Endogenous Metabolite Others
    Chimax-O (Endo-chitosanase) is an endochitosanase belonging to the GH46 family that catalyzes chitosan substrate to produce chitobiose and D-glucosamine (GlcN). Chimax-O acts in a stochastic intra-action manner, producing chitosan derivatives with different degrees of polymerization (DP) ≤2 .
    Chimax-O
  • HY-P0024A

    DG3173 TFA; PTR-3173 TFA

    Somatostatin Receptor Endocrinology Cancer
    Veldoreotide (DG3173) TFA a somatostatin analogue, binds to and activate the somatostatin receptors (SSTR) 2, 4, and 5. Veldoreotide TFA inhibits growth hormone (GH) secretion in adenomas compared with Octreotide (HY-P0036). Veldoreotide has the potential to be used as pain modulating agent
    Veldoreotide TFA
  • HY-13913
    NS-398
    Maximum Cited Publications
    16 Publications Verification

    COX Inflammation/Immunology Cancer
    NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM.
    NS-398
  • HY-P1773

    Insulin-like Growth Factor I (30-41)

    Insulin Receptor Metabolic Disease Inflammation/Immunology
    IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions) .
    IGF-I (30-41)
  • HY-115661

    Bacterial Infection
    Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively .
    Bisdionin C
  • HY-P1773A

    Insulin-like Growth Factor I (30-41) (TFA)

    IGF-1R Metabolic Disease Inflammation/Immunology
    IGF-I (30-41) (TFA) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions) .
    IGF-I (30-41) (TFA)
  • HY-153485

    ISIS 766720; IONIS-GHR-LRx

    GHR Small Interfering RNA (siRNA) Others
    Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.
    Cimdelirsen
  • HY-P4750

    GHSR Endocrinology
    Acetyl-(D-Arg2)-GRF (1-29) amide (human) is an antagonist of growth hormone releasing factor (GRF). Acetyl-(D-Arg2)-GRF (1-29) amide (human) inhibits the release of growth hormone (GH) and can be used for endocrine research .
    Acetyl-(D-Arg2)-GRF (1-29) amide (human)
  • HY-153485A

    ISIS 766720 sodium; IONIS-GHR-LRx sodium

    GHR Small Interfering RNA (siRNA) Others
    Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.
    Cimdelirsen sodium
  • HY-14734B

    RC-1291 Fumarate; ONO-7643 Fumarate

    GHSR Endocrinology Cancer
    Anamorelin (RC-1291) Fumarate is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. Anamorelin Fumarate can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin Fumarate can be used in the research of anorexia and cancer cachexia .
    Anamorelin Fumarate
  • HY-14734
    Anamorelin
    5+ Cited Publications

    RC-1291; ONO-7643

    GHSR Endocrinology Cancer
    Anamorelin (RC-1291) is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. Anamorelin can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin can be used in the research of anorexia and cancer cachexia .
    Anamorelin
  • HY-14734A
    Anamorelin hydrochloride
    5+ Cited Publications

    RC-1291 hydrochloride; ONO-7643 hydrochloride

    GHSR Endocrinology Cancer
    Anamorelin (RC-1291) hydrochloride is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. Anamorelin hydrochloride can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin hydrochloride can be used in the research of anorexia and cancer cachexia .
    Anamorelin hydrochloride
  • HY-149902

    Deubiquitinase Cancer
    USP8-IN-3 (Compd U51) is a deubiquitinase USP8 inhibitor with an IC50 value of 4.0 μM. USP8-IN-3 also inhibits the proliferation of GH3 and H1957 cells with GI50s of 37.03 μM and 6.01 μM, respectively .
    USP8-IN-3

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