2. Gene
  3. Cp - ceruloplasmin Gene

Cp - ceruloplasmin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as CERP

Gene ID: 24268 | Gene type: protein coding

About Cp

Summary

Enables copper ion binding activity. Involved in several processes, including female pregnancy; gland development; and response to copper ion. Located in extracellular space. Is anchored component of plasma membrane. Used to study brain edema and iron metabolism disease. Biomarker of Wilson disease; brain ischemia; heart disease; and hyperthyroidism. Human ortholog(s) of this gene implicated in aceruloplasminemia; epilepsy; and hemosiderosis. Orthologous to human CP (ceruloplasmin). [provided by Alliance of Genome Resources, Apr 2022]

Cp Products(2)

mRNA Protein Name
NM_001270961.1 NP_001257890.1 ceruloplasmin isoform 2 precursor
NM_012532.2 NP_036664.2 ceruloplasmin isoform 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables copper ion binding IDA
IDA: Inferred from direct assay
12099680 RGD
Biological Process GO Annotation Evidence Reference Source
involved in female pregnancy IEP
IEP: Inferred from expression pattern
28089327 RGD
involved in lactation IEP
IEP: Inferred from expression pattern
28089327 RGD
involved in liver development IEP
IEP: Inferred from expression pattern
2332446 RGD
involved in lung development IEP
IEP: Inferred from expression pattern
2332446 RGD
involved in mammary gland involution IEP
IEP: Inferred from expression pattern
28089327 RGD
involved in response to copper ion IDA
IDA: Inferred from direct assay
19700037 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
16597684 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
10660599 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
10660599 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ceruloplasmin

bilitranslocase

ceruloplasmin (ferroxidase)

Related Agents

Approval
Bioactive Molecules (34)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-40354 Tofacitinib 99.99% Yes
HY-50896 Erlotinib 99.99% Yes
HY-14275 Verapamil 99.96% Yes
HY-A0064 Verapamil hydrochloride 99.98% Yes
HY-17506 Azithromycin Inhibitor ≥98.0% Yes
HY-40354A Tofacitinib citrate 99.94% Yes
HY-12008 Erlotinib Hydrochloride 99.94% Yes
HY-B0334 Sulbactam Inhibitor 99.75% Unkown
HY-10019 Varenicline Agonist 99.92% Yes
HY-B0253 Piroxicam Inhibitor 99.78% Unkown
HY-14542 Ziprasidone Antagonist 99.81% Unkown
HY-B0210A Cefoperazone sodium salt Inhibitor 99.72% Yes
HY-10021 Varenicline Tartrate 99.96% Yes
HY-B0334A Sulbactam sodium Inhibitor 99.66% Unkown
HY-10020 Varenicline Hydrochloride Agonist 99.95% Yes
HY-B0254 Glipizide Inhibitor 99.83% Unkown
HY-A0038 Lasofoxifene tartrate Modulator 99.93% Unkown
HY-13538 Gemcitabine elaidate 99.14% Unkown
HY-17506A Azithromycin hydrate Inhibitor ≥98.0% Yes
HY-17484 Ampiroxicam Inhibitor 98.43% Unkown
HY-13010 Laquinimod 99.46% Yes
HY-17407 Ziprasidone hydrochloride monohydrate Antagonist 98.11% Unkown
HY-A0037 Lasofoxifene 99.27% Unkown
HY-B0915 Orbifloxacin Inhibitor 99.78% Unkown
HY-108880 Carindacillin sodium Inhibitor 96.73% Unkown
HY-B0210AR Cefoperazone (sodium salt) (Standard) Inhibitor / Unkown
HY-108288 Sulbactam pivoxil Inhibitor ≥98.0% Unkown
HY-10019A Varenicline dihydrochloride Agonist 99.21% Yes
HY-A0064R Verapamil (hydrochloride) (Standard) / Unkown
HY-B0501 Danofloxacin mesylate Inhibitor 99.87% Unkown
HY-14542A Ziprasidone hydrochloride Antagonist / Unkown
HY-14542B Ziprasidone mesylate trihydrate Antagonist / Unkown
HY-14542C Ziprasidone mesylate Antagonist / Unkown
HY-12008A Erlotinib mesylate / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9918 Tremelimumab 99.50% Unkown
HY-P99965 Crovalimab Inhibitor 98.61% Unkown
Clinical Phase
Bioactive Molecules (31)
Cat. No. Product Name Effect
Purity Phase
HY-N0678 Icaritin Inducer 99.27% Phase 4
HY-124498 Oxantel Inhibitor / Phase 4
HY-10211 Tanespimycin 99.01% Phase 3
HY-13223 Crenolanib 99.68% Phase 3
HY-105284 Sulopenem Inhibitor 99.70% Phase 3
HY-12089 Torcetrapib Inhibitor 99.88% Phase 3
HY-105028 Tenidap Inhibitor 99.32% Phase 3
HY-10871 Otenabant Antagonist 99.23% Phase 3
HY-14941 Elacytarabine ≥98.0% Phase 3
HY-10871A Otenabant Hydrochloride Antagonist / Phase 3
HY-W062904 Laquinimod sodium Inhibitor / Phase 3
HY-105086 Pamaqueside Inhibitor / Phase 3
HY-W018061 Traxoprodil Antagonist 99.92% Phase 2
HY-14674 CP-724714 98.72% Phase 2
HY-13302 CP-547632 Inhibitor 99.16% Phase 2
HY-13302B CP-547632 hydrochloride Inhibitor 99.88% Phase 2
HY-14839 Evatanepag Agonist 99.78% Phase 2
HY-13538A Gemcitabine elaidate hydrochloride 99.89% Phase 2
HY-19687 Zopolrestat Inhibitor 99.92% Phase 2
HY-10049 CP 122721 Antagonist / Phase 2
HY-105192 CP-122288 Agonist / Phase 2
HY-14129 CP 316311 Antagonist / Phase 2
HY-149769 CP-506 Substrate / Phase 2
HY-16372 CP 461 / Phase 2
HY-19193 CP-105696 Antagonist 99.93% Phase 1
HY-16373 CP-609754 Inhibitor 99.21% Phase 1
HY-12946 BI 653048 Inhibitor 99.84% Phase 1
HY-P1717 AMY-101 Inhibitor / Phase 1
HY-13223A Crenolanib benzenesulfonate / Phase 1
HY-12946A BI 653048 phosphate Inhibitor / Phase 1
HY-U00401 (Rac)-CP-609754 Inhibitor / Phase 1
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99197 Figitumumab Inhibitor 96.89% Phase 3
Pre-clinical Phase
Bioactive Molecules (244)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12815 MCC950 Inhibitor 99.62% Unkown
HY-12815A MCC950 sodium Inhibitor 99.75% Unkown
HY-12050 CP-673451 Inhibitor 99.69% Unkown
HY-B1368 Fenclonine Inhibitor 99.92% Unkown
HY-108347 CP-100356 hydrochloride Inhibitor 99.68% Unkown
HY-112136 TAO Kinase inhibitor 1 99.81% Unkown
HY-P1717A AMY-101 TFA Inhibitor 99.89% Unkown
HY-13525 CP-91149 99.80% Unkown
HY-139330 MGH-CP1 Inducer 99.56% Unkown
HY-P1717B AMY-101 acetate Inhibitor 99.93% Unkown
HY-12506A Naspm trihydrochloride Inhibitor 98.50% Unkown
HY-108615 CP-316819 Inhibitor ≥99.0% Unkown
HY-100207 CP21R7 Inhibitor 99.74% Unkown
HY-W018845 [Ir(Cp-)Cl2]2 ≥99.0% Unkown
HY-15259 CP-640186 Inhibitor 99.72% Unkown
HY-103068 Diethyl-pythiDC 99.90% Unkown
HY-115319 CP-24879 hydrochloride 99.59% Unkown
HY-12506 Naspm Inhibitor 96.30% Unkown
HY-15662 Tulathromycin A Inhibitor ≥98.0% Unkown
HY-49116 CP26 Inhibitor ≥98.0% Unkown
HY-125835 CP-10 Inhibitor 98.41% Unkown
HY-123772 CDK5 inhibitor 20-223 Inhibitor 99.62% Unkown
HY-18343A CP-31398 dihydrochloride p53 Activator 99.63% Unkown
HY-11002 CP-466722 Inhibitor 99.74% Unkown
HY-B1161A S-Methoprene Antagonist 98.58% Unkown
HY-130257 CP5V Inhibitor 99.31% Unkown
HY-W019734 [Rh(Cp-)Cl2]2 98.20% Unkown
HY-14899 Taprenepag Agonist 98.79% Unkown
HY-15259A CP-640186 hydrochloride Inhibitor 99.90% Unkown
HY-150082 CP681301 Inhibitor 99.18% Unkown
HY-125843 Pomalidomide-PEG1-C2-N3 99.91% Unkown
HY-103151 CP94253 hydrochloride Agonist 98.84% Unkown
HY-113955 CP-346086 99.02% Unkown
HY-130841 Apcin-A Inhibitor ≥98.0% Unkown
HY-17506S Azithromycin-d3 Inhibitor ≥98.0% Unkown
HY-120160 Darglitazone Agonist 99.19% Unkown
HY-15243 Capromorelin Tartrate Agonist 98.19% Unkown
HY-19396 Ingliforib Inhibitor 99.07% Unkown
HY-12129 CP 154526 hydrochloride Antagonist 99.76% Unkown
HY-13340 VU0152100 Modulator 98.98% Unkown
HY-105064D Zoniporide hydrochloride hydrate Inhibitor 99.37% Unkown
HY-116006 Bis-PEG5-acid 99.90% Unkown
HY-130296 Palbociclib-propargyl 95.23% Unkown
HY-40354AS Tofacitinib-d3 citrate 99.14% Unkown
HY-14130 CP 376395 Antagonist 99.68% Unkown
HY-105445 CP-113818 Inhibitor 99.13% Unkown
HY-13256 Desmethyl Erlotinib hydrochloride 99.23% Unkown
HY-113421 Linoleoyl ethanolamide ≥98.0% Unkown
HY-116530 9-Cyclopentyladenine monomethanesulfonate Inhibitor 99.16% Unkown
HY-19360 Sulprostone Agonist ≥99.0% Unkown
HY-103070 PythiDC Inhibitor 99.33% Unkown
HY-107634 CP-20961 Inducer 98.34% Unkown
HY-116699 CP-868388 free base Agonist 99.66% Unkown
HY-12008S Erlotinib-d6 hydrochloride 98.13% Unkown
HY-124815 CP-312 Inducer 99.69% Unkown
HY-15543A CP-809101 hydrochloride Agonist 99.37% Unkown
HY-A0064S Verapamil-d3 hydrochloride 99.57% Unkown
HY-119721 CP-424174 Inhibitor 98.03% Unkown
HY-164605 (6S)-CP-470711 Inhibitor 98.75% Unkown
HY-130452 NOS1-IN-1 Inhibitor ≥95.0% Unkown
HY-101357A CP 93129 dihydrochloride Agonist ≥99.0% Unkown
HY-105064 Zoniporide Inhibitor 99.89% Unkown
HY-116893 Diethyl bipy55'DC Inhibitor 98.79% Unkown
HY-118140 ZCZ011 Modulator 99.43% Unkown
HY-12095 CB1 inverse agonist 2 Agonist 99.15% Unkown
HY-121755 Tibric acid / Unkown
HY-13256A Desmethyl Erlotinib 98.77% Unkown
HY-136609 5-AMAM-2-CP Agonist 98.21% Unkown
HY-138879 CP-601927 Agonist 98.24% Unkown
HY-40354S Tofacitinib-13C3 97% Unkown
HY-B0254S Glipizide-d11 Inhibitor 96.36% Unkown
HY-W018061C (R,R)-Traxoprodil Antagonist 99.00% Unkown
HY-13010S Laquinimod-d5 Inhibitor 98.25% Unkown
HY-B0334AS Sulbactam-d5 sodium Inhibitor 99.90% Unkown
HY-131959 (S,R,S)-AHPC-PEG5-Boc 95.29% Unkown
HY-101803 CP671305 Inhibitor 99.95% Unkown
HY-108482 CP-96,345 Inhibitor ≥99.0% Unkown
HY-108623 Atizoram Inhibitor 96.3% Unkown
HY-112199 CP-447697 Antagonist 99.70% Unkown
HY-123039 CP-532623 Inhibitor ≥99.0% Unkown
HY-13302C CP-547632 TFA Inhibitor 99.42% Unkown
HY-136608 5-AAM-2-CP Agonist 99.22% Unkown
HY-138879A (Rac)-CP-601927 hydrochloride Agonist 99.72% Unkown
HY-138879B CP-601932 Agonist 99.74% Unkown
HY-15541 Zaltidine Antagonist 99.49% Unkown
HY-163101 CP-96021 Antagonist 98.04% Unkown
HY-18663 CP-465022 Antagonist 98.47% Unkown
HY-50896S Erlotinib-d6 Inhibitor / Unkown
HY-B0253S Piroxicam-d3 Inhibitor 99.68% Unkown
HY-W011085 CP-471474 Inhibitor 99.2% Unkown
HY-101639 CP-409092 Agonist / Unkown
HY-118639 CP-74006 Inhibitor 98.86% Unkown
HY-17506S1 Azithromycin-13C,d3 99.90% Unkown
HY-U00004 OSIP-486823 Inhibitor ≥98.0% Unkown
HY-145126 CP-628006 Activator / Unkown
HY-18343 CP-31398 p53 Activator / Unkown
HY-10019AS1 Varenicline-d4 hydrochloride Agonist / Unkown
HY-10019S Varenicline-d4 Agonist / Unkown
HY-10019S1 Varenicline-15N,13C,d2 Agonist / Unkown
HY-10020S Varenicline-15N3 hydrochloride Agonist / Unkown
HY-100280 Pirolate Antagonist / Unkown
HY-100332 CP 375 / Unkown
HY-10049A CP 122721 hydrochloride Antagonist / Unkown
HY-101357 CP 93129 Agonist / Unkown
HY-101558B Elzasonan hydrochloride Antagonist / Unkown
HY-103092 CP-135807 Agonist / Unkown
HY-103151A CP94253 Agonist / Unkown
HY-103379 CP 376395 hydrochloride Antagonist / Unkown
HY-105028S Tenidap-d3 Inhibitor / Unkown
HY-105064B Zoniporide hydrochloride Inhibitor / Unkown
HY-105064C Zoniporide dihydrochloride Inhibitor / Unkown
HY-105157 Icopezil Inhibitor / Unkown
HY-105205 Terlakiren Inhibitor / Unkown
HY-107013 CP-544439 Inhibitor / Unkown
HY-107213 Tulathromycin B Inhibitor / Unkown
HY-107233 Saponin CP4 / Unkown
HY-107235 Saponin CP6 / Unkown
HY-108571 CP-775146 Agonist 98.70% Unkown
HY-109855 CP-67015 Inhibitor / Unkown
HY-112742 CP-195543 Antagonist / Unkown
HY-113642 CP-67804 / Unkown
HY-113955A CP-346086 dihydrate / Unkown
HY-114540 CP-339818 / Unkown
HY-116082 CP 226269 Agonist 99.65% Unkown
HY-117172 CP320626 Inhibitor / Unkown
HY-117803 CP 461 free base / Unkown
HY-117868 NC-174 / Unkown
HY-118056 ABD459 Antagonist / Unkown
HY-118842 Sunepitron hydrochloride / Unkown
HY-120076 CP-293019 Antagonist / Unkown
HY-12008S1 Erlotinib-13C6 hydrochloride / Unkown
HY-120160A Darglitazone Sodium Agonist / Unkown
HY-12079 CP-481715 Antagonist / Unkown
HY-12130 CP 154526 Antagonist / Unkown
HY-12145 CP-99994 hydrochloride / Unkown
HY-121866 CP-84364 Inhibitor / Unkown
HY-122109A Levonantradol hydrochloride Agonist / Unkown
HY-122118 Lambast / Unkown
HY-122483 Diethyl pyimDC Inhibitor / Unkown
HY-123139 Flutroline / Unkown
HY-123203 CP-608039 Agonist / Unkown
HY-130205 Milacemide hydrochloride Inhibitor / Unkown
HY-13256AS1 Desmethyl Erlotinib-d4-1 / Unkown
HY-135254 CP-46665 dihydrochloride Inhibitor / Unkown
HY-136951 cp028 Inhibitor / Unkown
HY-14275S1 Verapamil-d7 / Unkown
HY-14411 JNK-1-IN-1 Inhibitor / Unkown
HY-14542S Ziprasidone-d8 Antagonist / Unkown
HY-146815 CP19 / Unkown
HY-14839A Evatanepag sodium Agonist / Unkown
HY-149495 CP-07 Degrader / Unkown
HY-150665S N-Dansyl-d6 1,4-diaminobutane, 97% (CP) / Unkown
HY-151267 SARS-CoV-2-IN-25 Inhibitor / Unkown
HY-151267A SARS-CoV-2-IN-25 disodium Inhibitor / Unkown
HY-15242 Capromorelin Activator / Unkown
HY-155044 TMV-IN-5 Inhibitor / Unkown
HY-155045 TMV-IN-6 Inhibitor / Unkown
HY-15541A Zaltidine dihydrochloride Antagonist / Unkown
HY-161597 PROTAC DYRK2 degrader 1 / Unkown
HY-162807 TMV-IN-10 Inhibitor / Unkown
HY-164749 K-Ras-IN-4 Inhibitor / Unkown
HY-167946 CP-866087 Antagonist / Unkown
HY-168971 Paeoniflorin-6′-O-benzene sulfonate / Unkown
HY-169232 PCC16 chloride Degrader / Unkown
HY-16946 CP-610431 Inhibitor / Unkown
HY-171113 CP-LC-1074 / Unkown
HY-176027 CP-LC-1422 / Unkown
HY-18228 CP-352664 Inhibitor / Unkown
HY-18663A CP-465022 maleate Antagonist / Unkown
HY-18663B CP-465022 hydrochloride Antagonist / Unkown
HY-19048 CP-66948 Antagonist / Unkown
HY-50896S1 Erlotinib-13C6 / Unkown
HY-A0064S1 Verapamil-d6 hydrochloride / Unkown
HY-B0253S1 Piroxicam-d4 Inhibitor / Unkown
HY-B0334AS1 Sulbactam-d2 sodium / Unkown
HY-B0501S Danofloxacin-d3 mesylate Inhibitor / Unkown
HY-B0915S Orbifloxacin-d5 hydrochloride Inhibitor / Unkown
HY-D1346 610CP / Unkown
HY-D1418 CP-BP-SFAC / Unkown
HY-N10268 3-Hydroxyterphenyllin / Unkown
HY-P10384 SPSB2-iNOS inhibitory cyclic peptide-2 Inhibitor / Unkown
HY-P10385 SPSB2-iNOS inhibitory cyclic peptide-3 / Unkown
HY-P10828 MAPI Inhibitor / Unkown
HY-P2024 CP-85339 Inhibitor / Unkown
HY-RS03079 CP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-U00070 Dirlotapide ≥99.0% Unkown
HY-W008914 (E/Z)-CP-724714 Inhibitor / Unkown
HY-W018061A Traxoprodil mesylate Antagonist / Unkown
HY-W115746A Ethyl cellulose (viscosity 10 cP) / Unkown
HY-W115746B Ethyl cellulose (viscosity 300 cP) / Unkown
HY-W772850 Fenclonine hydrochloride Inhibitor / Unkown
HY-10019S2 Varenicline-13C15N Agonist / Unkown
HY-100316 CP-96486 Antagonist / Unkown
HY-101731 CP-96021 hydrochloride Antagonist / Unkown
HY-105028A Tenidap sodium Inhibitor / Unkown
HY-105284A Sulopenem sodium Inhibitor / Unkown
HY-10814 CP-810123 Agonist / Unkown
HY-108574 CP 339818 hydrochloride Inhibitor 99.61% Unkown
HY-111129 CP-66713 Antagonist / Unkown
HY-113421S Linoleoyl ethanolamide-d4 / Unkown
HY-123289 CP-690550A Inhibitor / Unkown
HY-123311 CP59430 Antagonist / Unkown
HY-123571 CP-199330 Antagonist / Unkown
HY-123582 CP-866,087 / Unkown
HY-129698 MS-073 Inhibitor / Unkown
HY-129785 CP-220629 Inhibitor / Unkown
HY-14275S Verapamil-d3 / Unkown
HY-14275S2 Verapamil-d6 / Unkown
HY-149769A CP-506 mesylate Substrate / Unkown
HY-150346 1cP-MiPLA / Unkown
HY-15543 CP-809101 Agonist / Unkown
HY-15661A OSI-413 free base / Unkown
HY-15662S Tulathromycin A-d7 Inhibitor / Unkown
HY-160901 CP-289,503 Inhibitor / Unkown
HY-163999 TMV-IN-12 Inhibitor / Unkown
HY-165129 CP102 / Unkown
HY-169723 CP 524515 Inhibitor / Unkown
HY-171185 CP-611,781 / Unkown
HY-171476 CP-865569 Antagonist / Unkown
HY-172014 CP-LC-0743 / Unkown
HY-172015 CP-LC-1143 / Unkown
HY-172016 CP-LC-0867 / Unkown
HY-172017 CP-LC-1254 / Unkown
HY-172018 CP-LC-0729 / Unkown
HY-172059 3C-P hydrochloride / Unkown
HY-40354S1 Tofacitinib-13C3,15N / Unkown
HY-40354S2 Tofacitinib-13C,d3 / Unkown
HY-40354S3 Tofacitinib-13C / Unkown
HY-40354S5 Tofacitinib-d3 / Unkown
HY-50896S2 Erlotinib-d4 / Unkown
HY-50896S3 Erlotinib-d8 / Unkown
HY-B0253A Piroxicam olamine Inhibitor / Unkown
HY-B0334S Sulbactam-d3 Inhibitor / Unkown
HY-N13047 Ningnanmycin / Unkown
HY-P10200 CP7-FP13-2 Inhibitor / Unkown
HY-RS16625 Cp Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23060 Cp Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-U00008 CP-28888 Inducer / Unkown
HY-W020041 CP 53631 Inhibitor / Unkown
HY-W187279 Karrikin 2 / Unkown
HY-W614725 Apcin-A monohydrochloride Inhibitor / Unkown
HY-W653875 Azithromycin-d5 Inhibitor / Unkown
HY-U00354 CP-060 Antagonist / Unkown
HY-U00270 CP-319340(free base) / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990147 Anti-Mouse VEGFR-2 Antibody (DC101-Mouse IgG2a) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cp NCBI NCBI:1356
Canis familiaris Cp NCBI NCBI:442963
Macaca fascicularis Cp NCBI
Mus musculus Cp NCBI NCBI:12870
Susscrofa domestica Cp NCBI
Macaca mulatta Cp NCBI NCBI:712210