Search Result

Results for "

transfection

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Autophagy (1) Bacterial (2) Biochemical Assay Reagents (27) c-Kit (1) DNA/RNA Synthesis (2) Endogenous Metabolite (2) Fluorescent Dye (2) HBV (1) Liposome (37) NF-κB (1) RET (11) Small Interfering RNA (siRNA) (1) VEGFR (1)
By Research Areas:	Cancer (17) Cardiovascular Disease (1) Infection (6) Inflammation/Immunology (7) Metabolic Disease (5)
Click Chemistry:	DBCO (1) Azide (1)
Oligonucleotides:	Pegylated Lipids (3) Liposomal Film-forming Agents (2) Emulsifiers (2) Cationic Lipids (23) Phospholipids (2) siRNA drugs (1) Cap Analogs (2) Cholesterol (3) siRNAs (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112301A

trans-Pralsetinib trans-BLU-667	RET	Cancer
trans-Pralsetinib (trans-BLU-667) is a *rearranged during transfection* (RET)** inhibitor extracted from patent US20170121312A1, Compound Example 129 .

HY-112754A

DOTAP chloride 5+ Cited Publications 1,2-Dioleoyl-3-trimethylammonium-propane chloride	Liposome	Cancer
DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .

HY-139200

DOTMA 1 Publications Verification	Liposome	Others
DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .

HY-159870

E12CA1A3	Biochemical Assay Reagents	Others
E12CA1A3 is a lipid transfection reagent that boosts the delivery efficiency of mRNA .

HY-W800783

DSTAP chloride CDESA	Liposome	Others
DSTAP chloride (CDESA) is a cationic lipid that used in the formation of lipid nanoparticles (LNPs). DORI chloride has high transfection efficiency .

HY-W800782

DC-6-14	Liposome	Others
DC-6-14 is a cationic lipid with gene transfection activity, which can be used for the synthesis of liposomes .

HY-142997

DOSPA	Liposome	Others
DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research .

HY-112301AR

trans-Pralsetinib (Standard)	RET	Cancer
trans-Pralsetinib (Standard) is the analytical standard of trans-Pralsetinib. This product is intended for research and analytical applications. trans-Pralsetinib (trans-BLU-667) is a rearranged during transfection (RET) inhibitor extracted from patent US20170121312A1, Compound Example 129 .

HY-144015

14:1 EPC trifluoromethanesulfonate	Liposome	Others
14:1 EPC trifluoromethanesulfonate is ethyl-phosphatidylcholine (EPC) with monounsaturated 14:1 chains. 14:1 EPC trifluoromethanesulfonate shows transfection activity. 14:1 EPC trifluoromethanesulfonate can be used for drug delivery .

HY-138912

Cho-Arg TFA	Liposome	Others
Cho-Arg TFA is a steroid-based cationic lipid with an L-Arginine headgroup. Cho-Arg TFA shows a remarkably high optimized plasmid DNA transfection efficacy .

HY-149037

GL67 N4-Spermine cholesteryl carbamate	Liposome	Others
GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

HY-149037A

GL67 pentahydrochloride N4-Spermine cholesteryl carbamate pentahydrochloride	Liposome	Others
GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

HY-112005

DOPE 3 Publications Verification Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine	Liposome Endogenous Metabolite	Inflammation/Immunology
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-148842

C14-4	Liposome	Others
C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity .

HY-112005GL

DOPE (GMP Like) Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)	Liposome	Inflammation/Immunology
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-P0311

LAH4	Bacterial	Infection
LAH4, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 possesses high plasmid DNA delivery capacities. LAH4 has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .

HY-P0311A

LAH4 TFA	Bacterial	Infection
LAH4 TFA, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 TFA possesses high plasmid DNA delivery capacities. LAH4 TFA has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .

HY-W250110

Polyethylenimine (branched) (30% in water) 5+ Cited Publications	Biochemical Assay Reagents	Infection Others
Polyethylenimine (branched) (30% in water) is a organic macromolecule with high cationic-charge-density potential. Polyethylenimine (branched) (30% in water) can ensnare DNA as well as attach to cell membrane. Polyethylenimine (branched) (30% in water) also retains a substantial buffering capacity at virtually any pH. Polyethylenimine (branched) (30% in water) is widely used as transfection reagent .

HY-153082

Firefly Luciferase circRNA	Fluorescent Dye	Others
Firefly Luciferase circRNA will express a luciferase protein, originally isolated from the Photinus pyralis (Firefly). Firefly Luciferase circRNA is ideal for monitoring and optimizing transfection efficiency and is recommended as a positive control for circular RNA transfections.

HY-W590549

Dioleyldimethylammonium chloride DODAC	Liposome	Others
Dioleyldimethylammonium chloride (DODAC) is a cationic lipid that can be used as transfection reagent .

HY-144022

16:0 DAP	Liposome	Others
16:0 DAP is a cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery .

HY-153081

eGFP circRNA	Fluorescent Dye	Others
The eGFP circRNA will express green fluorescent protein, originally isolated from the jellyfish, Aequorea victoria. The eGFP is a commonly used direct detection reporter in mammalian cell culture, yielding bright green fluorescence with an emission peak at 509 nm. The eGFP circRNA is therefore ideal for monitoring and optimizing transfection efficiency and is recommended as a positive control for circular RNA transfections.

HY-W800776

DORI 1,2-Dioleoyl-3-dimethyl-hydroxyethylammonium bromide	Liposome	Others
DORI is a cationic lipid that can deliver plasmid DNA in vitro. DORI has lower cytotoxicity and high transfection efficiency .

HY-34595

Pyrazoloadenine	RET	Cancer
Pyrazoloadenine is a potent RET (REarranged during Transfection) lung cancer oncoprotein inhibitor. Pyrazoloadenine shows anticancer activity .

HY-145024

RET-IN-6	RET	Cancer
RET-IN-6 is a potent RET (rearranged during transfection) inhibitor with an IC₅₀ of 4.57 nM (CN113461670A, compound 321) .

HY-125529

DMPAC-Chol Chol-T	Liposome	Others
DMPAC-Chol (Chol-T) is used for liposome formation. DMPAC-Chol (Chol-T) liposomes exhibits great transfection effciencies .

HY-144016

16:0 EPC chloride	Liposome	Others
16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery .

HY-W590676

Tetramyristoylcardiolipin diammonium TMCL diammonium	Liposome	Others
Tetramyristoylcardiolipin (TMCL) is an anionic lipid. Tetramyristoylcardiolipin can be used to study cell membrane function and drug delivery .

HY-144422

RET-IN-15	RET	Cancer
RET-IN-15 is a *rearranged during transfection* (RET) kinase** inhibitor extracted from patent WO2021115457A1 compound 51. RET-IN-15 can be used for the research of cancer .

HY-125734

DMHAPC-Chol	Liposome	Others
DMHAPC-Chol, a cationic lipid, contains a biodegradable carbamoyl linker and a hydroxyethyl group in the polar amino head moiety. DMHAPC-Chol can be used in both transfection experiments concerning plasmids or siRNA .

HY-W598178

93-O17O	Liposome	Others
93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .

HY-138913

2H-Cho-Arg TFA	Liposome	Cancer
2H-Cho-Arg (TFA) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.

HY-34595R

Pyrazoloadenine (Standard)	RET	Cancer
Pyrazoloadenine (Standard) is the analytical standard of Pyrazoloadenine. This product is intended for research and analytical applications. Pyrazoloadenine is a potent RET (REarranged during Transfection) lung cancer oncoprotein inhibitor. Pyrazoloadenine shows anticancer activity .

HY-158709

Cho-es-Lys	Biochemical Assay Reagents Liposome	Others
Cho-es-Lys is a cationic lipid synthesized by coupling natural cholesterol and amino acids, which has high gene transfection efficiency. Cho-es-Lys can be used in drug delivery research .

HY-145023

RET-IN-5	RET	Cancer
RET-IN-5 is a potent RET (rearranged during transfection) inhibitor with an IC₅₀s of 0.4 nM and 135.1 nM for RET and VEGFR2, respectively (WO2021213476A1, compound 18) .

HY-143545

RET-IN-8	RET	Cancer
RET-IN-8 is a *rearranged during transfection* (RET) kinase** inhibitor extracted from patent WO2021093720A1 compound I-1. RET-IN-8 can be used for the research of cancer .

HY-156936

RCB-02-4-8	Liposome	Others
RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .

HY-124493

Aluminon 2 Publications Verification ATA; Ammonium aurintricarboxylate; Aurintricarboxylic acid ammonium	Biochemical Assay Reagents	Others
Aluminon (ATA; Ammonium aurintricarboxylate; Aurintricarboxylic acid ammonium) is a complexometric titration indicator and can also be used as a nuclease inhibitor affecting transfection. Aluminon is a kind of biological materials or organic compounds that are widely used in life science research .

HY-174993

FHND5071 (1H)	RET	Cancer
FHND5071 (1H) is a selective inhibitor targeting the RET (rearrangement during transfection) tyrosine kinase. FHND5071 (1H) is promising for research of RET-driven cancers (such as thyroid cancer, lung cancer, etc.) .

HY-148859

AA-T3A-C12	Liposome	Metabolic Disease Inflammation/Immunology
AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). AA-T3A-C12 mediates great RNA delivery and transfection of activated fibroblasts .

HY-164035

DOPE-PEG-DBCO (MW 2000)	Biochemical Assay Reagents	Others
DOPE-PEG-DBCO (MW 2000) is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry .

HY-176753

Lipid 20b	Liposome	Inflammation/Immunology
Lipid 20b is a thiophene ionizable cationic lipid. Lipid 20 b can be used to generate lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. Lipid 20b can be studied in research for enhancing mRNA vaccine delivery and transfection efficacy .

HY-W1123922H

4-Arm-PEG-DSPE (MW 10000)	Biochemical Assay Reagents	Others
4-Arm-PEG-DSPE (MW 10000) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 10000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174964H

8-Arm-PEG-DSPE (MW 10000)	Biochemical Assay Reagents	Others
8-Arm-PEG-DSPE (MW 10000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 10000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174964E

8-Arm-PEG-DSPE (MW 5000)	Biochemical Assay Reagents	Others
8-Arm-PEG-DSPE (MW 5000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 5000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174964C

8-Arm-PEG-DSPE (MW 2000)	Biochemical Assay Reagents	Others
8-Arm-PEG-DSPE (MW 2000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 2000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-134541

SM-102 Maximum Cited Publications 26 Publications Verification	Liposome	Infection
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-W1123922A

4-Arm-PEG-DSPE (MW 600)	Biochemical Assay Reagents	Others
4-Arm-PEG-DSPE (MW 600) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 600) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174964

8-Arm-PEG-DSPE (MW 400)	Biochemical Assay Reagents	Others
8-Arm-PEG-DSPE (MW 400) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 1000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174957

6-Arm-PEG-DSPE (MW 400)	Biochemical Assay Reagents	Others
6-Arm-PEG-DSPE (MW 400) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 400) can be used for drug delivery, gene transfection, and vaccine delivery .

Cat. No.	Product Name

HY-L214

Liposome Library

140 compounds

Liposomes are spherical or multilayered spherical vesicles formed by the self-assembly of diacyl chain phospholipids (lipid bilayers) in aqueous solutions, which can be made from natural or synthetic phospholipids and exhibit good biocompatibility and low toxicity. They can serve as delivery carriers for various bioactive substances (such as drugs, proteins, nucleic acids, etc.) and are widely used in biomedical and chemical research. The main advantages of liposomes include 1) Protective effect: Their bilayer structure can protect encapsulated molecules from enzymatic degradation, oxidation, and other influences, extending stability and activity; 2) Active targeting: Surface modifications enable active targeting, enhancing the concentration of drugs or molecules in specific tissues or cells; 3) Customizability: The composition and structure of liposomes can be adjusted according to needs, such as altering phospholipid types or adding targeting ligands. These properties make liposomes highly valuable in developing novel drug delivery systems, serving as nucleic acid carriers for gene transfection, studying cellular uptake mechanisms and drug release kinetics, as well as developing functional food additives to improve the bioavailability of nutritional components.

MCE contains 140 liposome compounds, which is a good tool for lipidomic-related studies.

Cat. No.	Product Name	Type

HY-112005GL

DOPE (GMP Like) Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)	Fluorescent Dye
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-112754AGL

DOTAP chloride (GMP Like) 1,2-Dioleoyl-3-trimethylammonium-propane chloride (GMP Like)	Fluorescent Dye
DOTAP chloride (GMP Like) is the GMP Like class DOTAP chloride (HY-112754A). DOTAP chloride is a cationic lipid with good membrane fusion ability and biocompatibility. DOTAP chloride (GMP Like) can be used as an excipient for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) without the use of helper lipid .

Cat. No.	Product Name	Type

HY-112754A

DOTAP chloride 5+ Cited Publications 1,2-Dioleoyl-3-trimethylammonium-propane chloride	Drug Delivery
DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .

HY-139200

DOTMA

1 Publications Verification

Drug Delivery

DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .

HY-149037A

GL67 pentahydrochloride N4-Spermine cholesteryl carbamate pentahydrochloride	Drug Delivery
GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

HY-112005

DOPE 3 Publications Verification Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine	Drug Delivery
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-148842

C14-4	Drug Delivery
C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity .

HY-144022

16:0 DAP	Drug Delivery
16:0 DAP is a cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery .

HY-142997

DOSPA	Drug Delivery
DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research .

HY-144015

14:1 EPC trifluoromethanesulfonate	Drug Delivery
14:1 EPC trifluoromethanesulfonate is ethyl-phosphatidylcholine (EPC) with monounsaturated 14:1 chains. 14:1 EPC trifluoromethanesulfonate shows transfection activity. 14:1 EPC trifluoromethanesulfonate can be used for drug delivery .

HY-149037

GL67 N4-Spermine cholesteryl carbamate	Drug Delivery
GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

HY-112005GL

DOPE (GMP Like) Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)	Biochemical Assay Reagents
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-144016

16:0 EPC chloride	Drug Delivery
16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery .

HY-158709

Cho-es-Lys	Drug Delivery
Cho-es-Lys is a cationic lipid synthesized by coupling natural cholesterol and amino acids, which has high gene transfection efficiency. Cho-es-Lys can be used in drug delivery research .

HY-124493

Aluminon 2 Publications Verification ATA; Ammonium aurintricarboxylate; Aurintricarboxylic acid ammonium	Indicators
Aluminon (ATA; Ammonium aurintricarboxylate; Aurintricarboxylic acid ammonium) is a complexometric titration indicator and can also be used as a nuclease inhibitor affecting transfection. Aluminon is a kind of biological materials or organic compounds that are widely used in life science research .

HY-148859

AA-T3A-C12	Drug Delivery
AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). AA-T3A-C12 mediates great RNA delivery and transfection of activated fibroblasts .

HY-164035

DOPE-PEG-DBCO (MW 2000)	Drug Delivery
DOPE-PEG-DBCO (MW 2000) is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry .

HY-W1123922H

4-Arm-PEG-DSPE (MW 10000)	Drug Delivery
4-Arm-PEG-DSPE (MW 10000) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 10000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174964H

8-Arm-PEG-DSPE (MW 10000)	Drug Delivery
8-Arm-PEG-DSPE (MW 10000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 10000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174964E

8-Arm-PEG-DSPE (MW 5000)	Drug Delivery
8-Arm-PEG-DSPE (MW 5000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 5000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174964C

8-Arm-PEG-DSPE (MW 2000)	Drug Delivery
8-Arm-PEG-DSPE (MW 2000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 2000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-134541

SM-102 Maximum Cited Publications 26 Publications Verification	Drug Delivery
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-W1123922A

4-Arm-PEG-DSPE (MW 600)	Drug Delivery
4-Arm-PEG-DSPE (MW 600) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 600) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174964

8-Arm-PEG-DSPE (MW 400)	Drug Delivery
8-Arm-PEG-DSPE (MW 400) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 1000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174957

6-Arm-PEG-DSPE (MW 400)	Drug Delivery
6-Arm-PEG-DSPE (MW 400) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 400) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-141674

DMG-PEG	Drug Delivery
DMG-PEG is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .

HY-174957A

6-Arm-PEG-DSPE (MW 600)	Drug Delivery
6-Arm-PEG-DSPE (MW 600) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 600) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174964A

8-Arm-PEG-DSPE (MW 600)	Drug Delivery
8-Arm-PEG-DSPE (MW 600) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 600) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-W1123922D

4-Arm-PEG-DSPE (MW 3400)	Drug Delivery
4-Arm-PEG-DSPE (MW 3400) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 3400) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174957H

6-Arm-PEG-DSPE (MW 10000)	Drug Delivery
6-Arm-PEG-DSPE (MW 10000) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 10000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-W1123922C

4-Arm-PEG-DSPE (MW 2000)	Drug Delivery
4-Arm-PEG-DSPE (MW 2000) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 2000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174957C

6-Arm-PEG-DSPE (MW 2000)	Drug Delivery
6-Arm-PEG-DSPE (MW 2000) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 2000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174957B

6-Arm-PEG-DSPE (MW 1000)	Drug Delivery
6-Arm-PEG-DSPE (MW 1000) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 1000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174964D

8-Arm-PEG-DSPE (MW 3400)	Drug Delivery
8-Arm-PEG-DSPE (MW 3400) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 3400) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-W1123922E

4-Arm-PEG-DSPE (MW 5000)	Drug Delivery
4-Arm-PEG-DSPE (MW 5000) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 5000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-W1123922B

4-Arm-PEG-DSPE (MW 1000)	Drug Delivery
4-Arm-PEG-DSPE (MW 1000) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 1000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174957E

6-Arm-PEG-DSPE (MW 5000)	Drug Delivery
6-Arm-PEG-DSPE (MW 5000) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 5000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174964B

8-Arm-PEG-DSPE (MW 1000)	Drug Delivery
8-Arm-PEG-DSPE (MW 1000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 1000) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-W1123922

4-Arm-PEG-DSPE (MW 400)	Drug Delivery
4-Arm-PEG-DSPE (MW 400) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 400) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-174957D

6-Arm-PEG-DSPE (MW 3400)	Drug Delivery
6-Arm-PEG-DSPE (MW 3400) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 3400) can be used for drug delivery, gene transfection, and vaccine delivery .

HY-112764

DMG-PEG 2000 5+ Cited Publications	Drug Delivery
DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .

HY-112760

18:0 mPEG2000 PE sodium 1 Publications Verification DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium	Drug Delivery
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .

HY-112754AGL

DOTAP chloride (GMP Like) 1,2-Dioleoyl-3-trimethylammonium-propane chloride (GMP Like)	Biochemical Assay Reagents
DOTAP chloride (GMP Like) is the GMP Like class DOTAP chloride (HY-112754A). DOTAP chloride is a cationic lipid with good membrane fusion ability and biocompatibility. DOTAP chloride (GMP Like) can be used as an excipient for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) without the use of helper lipid .

HY-145973A

3'OMe-m7GpppAmpG (ammonium) solution (100mM) m7(3'OMeG)(5')ppp(5')(2'OMeA)pG ammonium solution (100mM)	Gene Sequencing and Synthesis
3'OMe-m7GpppAmpG ammonium solution (100mM) is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG ammonium shows a significant translational efficiency. 3'OMe-m7GpppAmpG ammonium can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .

HY-W134327A

DEAE-dextran (MW 500000)

Diethylaminoethyl dextran (MW 500000)

Biochemical Assay Reagents

DEAE-Dextran (MW 500000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds and modified with diethylaminoethyl (DEAE) groups. DEAE-Dextran is a cationic molecule that can be used as a transfection reagent to deliver nucleic acids such as DNA or RNA into cells. Its positive charge interacts with negatively charged cell membranes, facilitating the uptake of nucleic acids. DEAE-Dextran can also be used as an ion-exchange chromatography resin, allowing the separation and purification of biomolecules based on their charge.

HY-W127378

DOTAP methylsulfate

5+ Cited Publications

1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate

Drug Delivery

DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design[1][2].

HY-150229

306-N16B

Drug Delivery

306-N16B is a selective lung-targeted lipid nanoparticle that reversibly targets lung endothelial cells and specific immune cells through selective adsorption of a protein corona mediated by differences in tail structure (such as fibrinogen β/γ chain). 306-N16B binds to specific plasma proteins in the blood to form a protein corona, which guides the particles to be enriched in the lungs, releases mRNA and promotes target cell gene expression, exerts efficient lung cell transfection activity, and can precisely regulate gene delivery of different cell types in the lungs (such as endothelial cells and macrophages). 306-N16B can be used in gene therapy technologies for hereditary lung diseases including pulmonary lymphangioleiomyomatosis (LAM), restoring tumor suppressor function by delivering Tsc2 mRNA, and can also be used for lung-specific mRNA vaccines and gene editing therapies .

Cat. No.	Product Name	Target	Research Area

HY-P0311A

LAH4 TFA	Bacterial	Infection
LAH4 TFA, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 TFA possesses high plasmid DNA delivery capacities. LAH4 TFA has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .

HY-P2530

KALA	Peptides	Others
KALA is an amphiphilic peptide that forms an α-helical structure at physiological pH. KALA modifies a plasmid DNA-encapsulating liposomal membrane and is used as a fusogenic peptide in order to achieve effective liver targeting and transfection of DNA via galactose receptors .

HY-P0311

LAH4	Bacterial	Infection
LAH4, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 possesses high plasmid DNA delivery capacities. LAH4 has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .

HY-P10443

ppTG20	Peptides	Others
ppTG20 is an amphiphilic cell penetrating peptide (KALA) that can be used for gene transfection. ppTG20 can bind to DNA, destabilize membranes, and mediate DNA transfection .

Cat. No.	Product Name

HY-K2015

*Lentivirus Transfection* Reagent** 1 Publications Verification
MCE Lentivirus Transfection Reagent is a new type of transfection reagent based on cationic polymer, which is suitable for lentivirus packaging and transfection. It significantly improves the efficiency of packaging and transfection, resulting in the production of more recombinant lentivirus.

HY-K2017

*siRNA/miRNA Transfection* Reagent** 3 Publications Verification
MCE siRNA/miRNA Transfection Reagent is a novel cationic polymer transfection reagent for siRNA and miRNA transfection.

HY-K2029

*HP PolyFast Transfection* Reagent**
MCE HP PolyFast Transfection Reagent is a novel cationic polymer transfection reagent for DNA and RNA transfection.

HY-K2016

*Protein Transfection* Reagent**
MCE Protein Transfection Reagent is a cationic lipid mixture for complexation with proteins, peptides, antibodies and other biologically active molecules to allow their direct intracellular delivery.

HY-K2014

*PEI Transfection* Reagent** 20+ Cited Publications
MCE PEI Transfection Reagent is designed based on 25 kDa PEI. It has high-efficiency, low-toxicity, strong-stability, and is suitable for many cell types, such as HEK-293、HEK-293T、CHO-K1、COS-1、COS-7、NIH/3T3、Sf9、HepG2 and HeLa et, even some hard-to-transfect cells. It can also be applied to large-scale recombinant protein expression and virus production.

HY-K2019

*OptiLNP RNA Transfection* Reagent (Stem Cells)**
MCE OptiLNP RNA Transfection Reagent (Stem Cells) is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient transfection of various RNA types into stem cells.

HY-K2021

*OptiLNP RNA Transfection* Reagent (Immune Cells)**
MCE OptiLNP RNA Transfection Reagent (Immune Cells) is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient transfection of various RNA types into immune cells.

HY-K2026

*OptiLNP Short-Chain RNA Transfection* Reagent**
MCE OptiLNP Short-Chain RNA Transfection Reagent is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient transfection of short-chain RNA into common cells.

HY-K2020

*OptiLNP RNA Transfection* Reagent (Primary Immune Cells)**
MCE OptiLNP RNA Transfection Reagent (Primary Immune Cells) is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient transfection of various RNA types into primary immune cells.

HY-K2018

*OptiLNP RNA Transfection* Reagent**
MCE OptiLNP RNA Transfection Reagent is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient transfection of various RNA types into common cells.

HY-K2022

In vivo OptiLNP RNA Transfection Reagent (Systemic Effect)
MCE In vivo OptiLNP RNA Transfection Reagent (Systemic Effect) is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient transfection of mRNA and short-chain RNA in experimental animals. The RNA functions systemically.

HY-K2023

In vivo OptiLNP RNA Transfection Reagent (Local Effect)
MCE In vivo OptiLNP RNA Transfection Reagent (Local Effect) is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient transfection of mRNA and short-chain RNA in experimental animals. The RNA functions locally.

HY-K2025

In vivo OptiLNP RNA Transfection Reagent (Lung-targeted)
MCE In vivo OptiLNP RNA Transfection Reagent (Lung-targeted) is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient transfection of mRNA and short-chain RNA via intravenous injection in experimental animals.

HY-K2024

In vivo OptiLNP RNA Transfection Reagent (Liver-targeted)
MCE In vivo OptiLNP RNA Transfection Reagent (Liver-targeted) is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient transfection of mRNA and short-chain RNA via intravenous injection in experimental animals.

HY-K2028

OptiLNP Gene Editing Kit (Immune Cells)
MCE OptiLNP Gene Editing Kit (Immune Cells) is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient co-transfection of Cas9 mRNA and sgRNA during gene editing inimmune cells.

HY-K2027

OptiLNP Gene Editing Kit
MCE OptiLNP Gene Editing Kit is a ready-to-use transfection reagent based on LNP technology. It is designed for the efficient co-transfection of Cas9 mRNA and sgRNA during gene editing in common cells (adherent or suspension cells).

HY-K1014

*PolyFast Transfection* Reagent** Maximum Cited Publications 27 Publications Verification
MCE PolyFast Transfection Reagent consists of cationic polymers and can introduce nucleic acids (DNA or RNA) into eukaryotic cells efficiently, including some hard-to-transfect cells.

Cat. No.	Product Name		Classification

HY-164035

DOPE-PEG-DBCO (MW 2000)		DBCO
DOPE-PEG-DBCO (MW 2000) is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry .

HY-151862

3-Azidopropylamine		Azide
3-Azidopropylamine is a click chemistry reagent containing an azide group. 3-Azidopropylamine can react with the starch sugar of potato starch for complexation and transfection of plasmid DNA . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-112754A

DOTAP chloride 5+ Cited Publications 1,2-Dioleoyl-3-trimethylammonium-propane chloride		Cationic Lipids
DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .

HY-139200

DOTMA 1 Publications Verification		Cationic Lipids
DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .

HY-149037A

GL67 pentahydrochloride N4-Spermine cholesteryl carbamate pentahydrochloride		Cationic Lipids
GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

HY-112005

DOPE 3 Publications Verification Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine		Phospholipids
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-W800783

DSTAP chloride CDESA		Cationic Lipids
DSTAP chloride (CDESA) is a cationic lipid that used in the formation of lipid nanoparticles (LNPs). DORI chloride has high transfection efficiency .

HY-W800782

DC-6-14		Cationic Lipids
DC-6-14 is a cationic lipid with gene transfection activity, which can be used for the synthesis of liposomes .

HY-142997

DOSPA		Cationic Lipids
DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research .

HY-144015

14:1 EPC trifluoromethanesulfonate		Cationic Lipids
14:1 EPC trifluoromethanesulfonate is ethyl-phosphatidylcholine (EPC) with monounsaturated 14:1 chains. 14:1 EPC trifluoromethanesulfonate shows transfection activity. 14:1 EPC trifluoromethanesulfonate can be used for drug delivery .

HY-138912

Cho-Arg TFA		Cholesterol
Cho-Arg TFA is a steroid-based cationic lipid with an L-Arginine headgroup. Cho-Arg TFA shows a remarkably high optimized plasmid DNA transfection efficacy .

HY-149037

GL67 N4-Spermine cholesteryl carbamate		Cationic Lipids
GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .

HY-148842

C14-4		Cationic Lipids Cationic Lipids
C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity .

HY-W590549

Dioleyldimethylammonium chloride DODAC		Cationic Lipids
Dioleyldimethylammonium chloride (DODAC) is a cationic lipid that can be used as transfection reagent .

HY-144022

16:0 DAP		Cationic Lipids
16:0 DAP is a cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery .

HY-W800776

DORI 1,2-Dioleoyl-3-dimethyl-hydroxyethylammonium bromide		Cationic Lipids
DORI is a cationic lipid that can deliver plasmid DNA in vitro. DORI has lower cytotoxicity and high transfection efficiency .

HY-125529

DMPAC-Chol Chol-T		Cationic Lipids
DMPAC-Chol (Chol-T) is used for liposome formation. DMPAC-Chol (Chol-T) liposomes exhibits great transfection effciencies .

HY-144016

16:0 EPC chloride		Cationic Lipids
16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery .

HY-W590676

Tetramyristoylcardiolipin diammonium TMCL diammonium		Phospholipids
Tetramyristoylcardiolipin (TMCL) is an anionic lipid. Tetramyristoylcardiolipin can be used to study cell membrane function and drug delivery .

HY-125734

DMHAPC-Chol		Cationic Lipids
DMHAPC-Chol, a cationic lipid, contains a biodegradable carbamoyl linker and a hydroxyethyl group in the polar amino head moiety. DMHAPC-Chol can be used in both transfection experiments concerning plasmids or siRNA .

HY-W598178

93-O17O		Cationic Lipids
93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .

HY-138913

2H-Cho-Arg TFA		Cholesterol
2H-Cho-Arg (TFA) is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection.

HY-158709

Cho-es-Lys		Cholesterol
Cho-es-Lys is a cationic lipid synthesized by coupling natural cholesterol and amino acids, which has high gene transfection efficiency. Cho-es-Lys can be used in drug delivery research .

HY-156936

RCB-02-4-8		Cationic Lipids
RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .

HY-148859

AA-T3A-C12		Cationic Lipids
AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). AA-T3A-C12 mediates great RNA delivery and transfection of activated fibroblasts .

HY-176753

Lipid 20b		Cationic Lipids
Lipid 20b is a thiophene ionizable cationic lipid. Lipid 20 b can be used to generate lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. Lipid 20b can be studied in research for enhancing mRNA vaccine delivery and transfection efficacy .

HY-134541

SM-102 Maximum Cited Publications 26 Publications Verification		Cationic Lipids
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-141674

DMG-PEG		Pegylated Lipids
DMG-PEG is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .

HY-112764

DMG-PEG 2000 5+ Cited Publications		Pegylated Lipids
DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .

HY-112760

18:0 mPEG2000 PE sodium 1 Publications Verification DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium		Pegylated Lipids
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .

HY-145973

3'OMe-m7GpppAmpG m7(3'OMeG)(5')ppp(5')(2'OMeA)pG		Cap Analogs
3'OMe-m7GpppAmpG is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG shows a significant translational efficiency. 3'OMe-m7GpppAmpG can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .

HY-145973A

3'OMe-m7GpppAmpG (ammonium) solution (100mM) m7(3'OMeG)(5')ppp(5')(2'OMeA)pG ammonium solution (100mM)		Cap Analogs
3'OMe-m7GpppAmpG ammonium solution (100mM) is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG ammonium shows a significant translational efficiency. 3'OMe-m7GpppAmpG ammonium can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .

HY-112764A

DMG-PEG 2000 (Excipient, GMP Like)		Emulsifiers Liposomal Film-forming Agents
DMG-PEG 2000 (Excipient, GMP Like) is the GMP Like class DMG-PEG 2000 (HY-112764), and can be used as pharmaceutical excipients. DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 (Excipient, GMP Like) is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .

HY-134541A

SM-102 (Excipient, GMP Like)		Emulsifiers Liposomal Film-forming Agents
SM-102 (Excipient, GMP Like) is the GMP Like class SM-102 (HY-134541), and can be used as pharmaceutical excipients. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 (Excipient, GMP Like) has higher transfection efficiency. SM-102 (Excipient, GMP Like) plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-150150

SiRNA Negative Control 5+ Cited Publications		siRNAs siRNA drugs
SiRNA Negative Control is a siRNA of 21 nucleotides, and can be used as a negative control. SiRNA Negative Control has no homology to most known gene sequence. SiRNA Negative Control is available with fluorescent labels, allowing rapid assessment of transfection efficiency. SiRNA Negative Control can be used in human, mouse and rat cells in vitro. SiRNA Negative Control can be used as experimental control benchmark, verification of experimental reliability and standardization reference. SiRNA Negative Control is a common negative control used in most research articles.

HY-W127378

DOTAP methylsulfate 5+ Cited Publications 1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate		Cationic Lipids
DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design[1][2].

HY-150229

306-N16B		Cationic Lipids
306-N16B is a selective lung-targeted lipid nanoparticle that reversibly targets lung endothelial cells and specific immune cells through selective adsorption of a protein corona mediated by differences in tail structure (such as fibrinogen β/γ chain). 306-N16B binds to specific plasma proteins in the blood to form a protein corona, which guides the particles to be enriched in the lungs, releases mRNA and promotes target cell gene expression, exerts efficient lung cell transfection activity, and can precisely regulate gene delivery of different cell types in the lungs (such as endothelial cells and macrophages). 306-N16B can be used in gene therapy technologies for hereditary lung diseases including pulmonary lymphangioleiomyomatosis (LAM), restoring tumor suppressor function by delivering Tsc2 mRNA, and can also be used for lung-specific mRNA vaccines and gene editing therapies .

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