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Results for "

tagged

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (1) ADC Linker (4) Amyloid-β (3) Apoptosis (2) ATM/ATR (1) ATP-binding cassette (ABC) transporters (1) Aurora Kinase (1) AUTACs (6) Autophagy (6) Bacterial (5) BCL6 (1) Biochemical Assay Reagents (30) c-Myc (1) Caspase (1) Deubiquitinase (1) Dipeptidyl Peptidase (1) DNA Alkylator/Crosslinker (1) DNA Stain (1) DNA/RNA Synthesis (3) Drug Intermediate (2) Drug Metabolite (3) E3 Ligase Ligand-Linker Conjugates (1) EGFR (3) Endogenous Metabolite (1) Endonuclease (1) Epigenetic Reader Domain (2) ERK (1) Fatty Acid Synthase (FASN) (1) FGFR (1) Filovirus (1) FKBP (5) Fluorescent Dye (29) Fungal (1) Hedgehog (1) Histone Methyltransferase (1) HIV (1) HSP (1) Influenza Virus (1) Interleukin Related (1) JNK (1) Ligands for E3 Ligase (1) LIM Kinase (LIMK) (1) Lipase (1) Liposome (3) LXR (1) MAP3K (1) Microtubule/Tubulin (1) Molecular Glues (2) Mucin (1) Natriuretic Peptide Receptor (NPR) (1) Neurokinin Receptor (1) Parasite (1) Phospholipase (1) Polo-like Kinase (PLK) (2) PROTAC Linkers (1) PROTACs (7) Protease Activated Receptor (PAR) (1) Proteasome (2) Pyruvate Kinase (1) Ribosomal S6 Kinase (RSK) (1) Ser/Thr Protease (2) SGK (1) Src (1) STAT (1) Thrombin (6) Transglutaminase (1) TRP Channel (1) Virus Protease (1) VSV (1) WDR5 (1)
By Research Areas:	Cancer (41) Cardiovascular Disease (9) Infection (9) Inflammation/Immunology (8) Metabolic Disease (8) Neurological Disease (10)
Click Chemistry:	Labeling and Fluorescence Imaging (3) Azide (9) Tetrazine (1) Alkynes (7)

147

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P0327

*T7 Tag* Peptide** 1 Publications Verification	Biochemical Assay Reagents	Others
T7 Tag Peptide is a protein tag derived from the N-terminal 11 residues of the major T7 capsid protein, gp 10. T7 Tag Peptide can be used in different immunoassays as well as affinity purification .

HY-D1288A

tris-NTA	Biochemical Assay Reagents	Others
tris-NTA is a His-tagged protein ligand, which can be used to bind His-tagged proteins .

HY-D2270

*Halo tag* TMR**	Fluorescent Dye	Others
Halo tag TMR is a red fluorescent dye composed of Halo tag ligand molecules and TMR. Halo tag can quickly and stably covalently bind to Halo protein with high specificity and affinity .

HY-129652

HaloAUTAC tt15	AUTACs	Cancer
HaloAUTAC tt15 is an autophagy-targeting chimera (AUTAC), that targets the Halo Tag carrying proteins, and degrades via the autophagy mechanism .

HY-116677

Tris(benzyltriazolylmethyl)amine 3 Publications Verification TBTA	Biochemical Assay Reagents	Others
Tris(benzyltriazolylmethyl)amine (TBTA) is a ligand that acts as a biochemical tool for the tagging of proteins and enzymes .

HY-136835

GJ071 oxalate	ATM/ATR	Neurological Disease
GJ071 oxalate induces ATM kinase activity in ataxia telangiectasia (A-T) cells carrying homozygous TGA or TAG stop codons .

HY-139163

BGSN3	Biochemical Assay Reagents	Others
BGSN3 is a good substrate for the SNAP-tag ^? and H ⁵ enzymes. The activities of SNAP-tag ^? and H ⁵ enzymes on BGSN3 are reasonable (IC₅₀=17.8 and 10 μM, respectively) . BGSN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-D1033

*Biotin-tagged* KR-33493**	Fluorescent Dye	Others
Biotin-tagged KR-33493 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-D1288

(Rac)-tris-NTA	Biochemical Assay Reagents	Others
(Rac)-tris-NTA is a His-tagged protein ligand, which can be used to bind His-tagged proteins .

HY-P5969

Cys-V5 Peptide	Biochemical Assay Reagents	Others
Cys-V5 Peptide, a tag peptide, is the V5 Peptide with an N-terminal cysteine. Cys-V5 Peptide can be used to label proteins

HY-139162

BGN3	Biochemical Assay Reagents	Others
BGN3 is a good substrate for the SNAP-tag ^? and H ⁵ enzymes. The activities of SNAP-tag ^? and H ⁵ enzymes on BGN3 are reasonable (IC₅₀= 15.6 and 23.5 μM, respectively) . BGN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-P3738

Osteocalcin (7-19) (human)	Biochemical Assay Reagents	Others
Osteocalcin (7-19) (human) is a peptide fragment of Osteocalcin, can be used as a peptide tag.

HY-145752

HaloPROTAC-E 1 Publications Verification	PROTACs SGK Autophagy	Cancer
HaloPROTAC-E is a potent Halo PROTAC degrader that reversibly induces degradation of two Halo-tagged endoplasmic reticulum-localized proteins, SGK3 and VPS34, with a DC₅₀ of 3-10 nM. HaloPROTAC-E significantly and selectively induces degradation of endogenous VPS34 complexes (VPS34, VPS15, Beclin1, and ATG14) labeled with Halo and inhibits autophagy.

HY-P0294

Hexa-His 6X His Tag	Biochemical Assay Reagents	Others
Hexa-His (6X His Tag) is a commonly used affinity tag made up of six histidine residues. HEXA-HIS can bind to affinity chromatography media containing transition metal ions like nickel (Ni ²⁺) or cobalt (Co ²⁺), making it useful for protein purification .

HY-131015

HaXS8	Biochemical Assay Reagents	Others
HaXS8 is a dimerizer that can promote a covalent and irreversible intracellular dimerization of HaloTag and SNAP-tagged proteins of interest. HaXS8 does not interfere with PI3K/mTOR signaling .

HY-P3763

Atrial Natriuretic Peptide (7-28), human, canine	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
Atrial Natriuretic Peptide (7-28), human, canine is a peptide fragment of atrial natriuretic peptide, can be used as a peptide tag .

HY-162175

TAMRA-isoADPr	Fluorescent Dye	Cancer
TAMRA-isoADPr is a fluorescently tagged iso-ADP-ribose tracer compound. TAMRA-isoADPr is a high-affinity tracer for the RNF146 WWE domain with a K_d of 45.2 nM .

HY-D2183

6-Carboxy-JF5252	Fluorescent Dye	Others
6-Carboxy-JF5252 is a fluorophore. 6-Carboxy-JF5252 can be used as probes, dyes, tags. 6-Carboxy-JF5252 can be used for the research of super-resolution imaging .

HY-P0239

HA Peptide 5+ Cited Publications	Influenza Virus	Inflammation/Immunology
HA Peptide (HA tag) is a nine amino acids peptide derived from the human influenza hemagglutinin (HA). HA Peptide is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry.

HY-P0223

FLAG peptide Maximum Cited Publications 18 Publications Verification	Biochemical Assay Reagents	Inflammation/Immunology
FLAG peptide is a multifunctional fusion tag for the purification of recombinant proteins. FLAG peptide maintances the natural folding of its fusing proteins. FLAG peptide can be removed by enterokinase, and eluted under non-denaturing conditions .

HY-P0319

3X FLAG peptide 5+ Cited Publications	Biochemical Assay Reagents	Others
3X FLAG peptides are FLAG-tagged peptides containing three repeats of the Asp-Tyr-Lys-Xaa-Xaa-Asp motif. 3X FLAG peptide can be used for protein separation and purification, and competitive elution with target proteins.

HY-N15358

15:0-18:1 DG	Drug Metabolite	Cardiovascular Disease Metabolic Disease
15:0-18:1 DG is a type of diacylglycerol (DAG). 15:0-18:1 DG can be produced by hydrolysis of triacylglycerol (TAG) in butter fat. 15:0-18:1 DG is promising for research of obesity, cardiovascular diseases, and dietary interventions .

HY-P3332A

*3x DYKDDDDK Tag* TFA**	Biochemical Assay Reagents	Others
DYKDDDDK peptide (FLAG) is a useful tool for investigating the function and localization of proteins whose antibodies (Abs) are not available. Often it is also used in a 3X FLAG format (3x DYKDDDDK Tag TFA) for purifying difficult proteins that accumulate in low abundance .

HY-160695

PT-179	Ligands for E3 Ligase Molecular Glues	Cancer
PT-179 is an orthogonal Thalidomide (HY-14658) derivative that targets cereblon without causing off-target degradation effects. PT-179 is able to specifically bind CRBN, form a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediate the degradation of the tagged protein. For example, PT-179 binds to the ubiquitin ligase substrate receptor cereblon by forming a complex with SD40 and efficiently degrades proteins N- or C-terminally fused to SD40 or SD36 (DC50 for eGFP: 4.5 nM and 14.3 nM). PT-179 can be used to develop compact protein degradation tagging platforms .

HY-147097A

EDA-DA TFA	Bacterial	Infection
EDA-DA is a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. EDA-DA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-147098

dTAG-47	PROTACs FKBP	Cancer
dTAG-47, heterobifunctional dTAG molecule, targets mutant FKBP12 (FKBP12 ^F36V). FKBP12 ^F36V serves as a degradation tag (dTAG) and is fused to a protein of interest. dTAG-47 can be used for the research of basal-like breast cancers (BBC) .

HY-147097

EDA-DA	Bacterial	Infection
EDA-DA, a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. Peptidoglycan (PG), an essential structure in the cell walls of the vast majority of bacteria, is critical for division and maintaining cell shape and hydrostatic pressure . EDA-DA is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P2467

Biotin-TAT (47-57)	Fluorescent Dye	Metabolic Disease
Biotin-TAT (47-57), a biotin tagged TAT, is a transactivator of transcription. Biotin-TAT (47-57) is one of the most widely used protein transduction domains (PTDs) into different primary cells is ATP- and temperature-dependent, indicating the involvement of endocytosis .

HY-111595

SAHA chloroalkane T1	Biochemical Assay Reagents	Cancer
SAHA chloroalkane T1 is a chloroalkane capture tag by tethering Vorinostat (SAHA) and a chloroalkane tag T1 .

HY-153631

*Sulfo-TAG* NHS ester disodium**	Drug Intermediate	Inflammation/Immunology
Sulfo-TAG NHS ester (disodium) is an N-hydroxysuccinimide ester that can be coupled to proteins via primary amine groups. Sulfo-TAG NHS ester (disodium) can be used for antibody labeling .

HY-W705969

tris-NTA TFA	Biochemical Assay Reagents	Others
tris-NTA TFA is a His-tagged protein ligand. tris-NTA TFA can be used alone or in combination with a fluorophore for purification and detection of His-tagged proteins .

HY-P99732

Minretumomab CC-49	Mucin	Cancer
Minretumomab (CC-49) is a murine monoclonal antibody against *TAG-72* (tumor-associated glycoprotein 72). Minretumomab is used in cancer and immunity research .

HY-171041

PreQ1-biotin	Bacterial	Others
PreQ1-biotin is a biotin conjugated preQ1 substrate. PreQ1-biotin is used for RNA-TAG (transglycosylation at guanosine) and DNA-TAG. PreQ1-biotin can be used for affinity tagging and pull-down of specific RNAs that have been modified selectively by E. coli tRNA guanine transglycosylase (TGT) .

HY-116683

116-9e MAL2-11B	HSP DNA/RNA Synthesis	Infection Cancer
116-9e (MAL2-11B) is a Hsp70 co-chaperone DNAJA1 inhibitor. 116-9e inhibits Simian Virus 40 (SV40) replication and DNA synthesis. 116-9e inhibits tumor antigen (TAg)’s endogenous ATPase activity and the TAg-mediated activation of Hsp70 .

HY-P3332

3x DYKDDDDK Tag	Biochemical Assay Reagents	Others
3x DYKDDDDK Tag is a useful tool for investigating the function and localization of proteins whose antibodies (Abs) are not available. Often it is also used in a 3X FLAG format (3x DYKDDDDK Tag) for purifying difficult proteins that accumulate in low abundance .

HY-101866

KKL-35	Bacterial	Infection
KKL-35 is a trans-translation tagging reaction inhibitor with an IC₅₀ of 0.9 μM.

HY-P99759

*Nogapendekin alfa (his tag)* IL-15N72D	Interleukin Related	Inflammation/Immunology Cancer
Nogapendekin alfa (his tag), a soluble protein subunit of a human interleukin (IL)-15 variant, is a superagonist of IL-15. Nogapendekin alfa (his tag) promotes the proliferation and viability of immune cells. Nogapendekin alfa (his tag) combines with Inbakicept (HY-P99661) at a ratio of 2:1, to form N-803 (Nogapendekin alfa inbakicept), an IL-15 cytokine antibody fusion protein. N-803 reduces tumor burden by activation of NK cells and CD8 ⁺ T cells .

HY-133869

cGMP-HTL cGMP-HaloTag-ligand	Autophagy	Cancer
cGMP-HTL contains a HT-ligand, a linker and the Cys-S-cGMP (autophagy tag). cGMP-HTL increases the K63-linked ubiquitination of mitochondria. AUTAC (autophagy-targeting chimera) is a novel targeted-clearance strategy that contains a degradation tag (guanine derivatives) and a warhead to provide target specificity .

HY-147169

Biotin-X-NTA	Fluorescent Dye	Others
Biotin-X-NTA can be used for detecting histidine-tagged proteins immobilized on nitrocellulose membranes .

HY-163208

VH 032 amide-alkylC9-amine hydrochloride (S,R,S)-AHPC-C9-NH2 hydrochloride	PROTAC Linkers	Others
VH 032 amide-alkylC9-amine hydrochloride (Linker 33) is TRK ligand conjugated to the degradation tag .

HY-D0021

Ethidium bromide 10+ Cited Publications EtBr; Homidium bromide	DNA Stain	Others
Ethidium bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.

HY-141676

HyT36	EGFR	Others
HyT36 is a low molecular weight hydrophobic tag that promotes the degradation of fusion protein and pseudokinase Her3 .

HY-P3208A

*Endoproteinase Lys-C (Tag-free)*	Biochemical Assay Reagents	Others
Endoproteinase Lys-C (Tag-free) is a protease that cleaves proteins on the C-terminal side of lysine residues and is commonly used for protein sequencing .

HY-136936

PYBG-BODIPY	Fluorescent Dye	Others
PYBG-BODIPY is a dye and has a role as a fluorochrome. PYBG-BODIPY specifically and efficiently labels the target genetically encoded SNAP-tags in live cells .

HY-P991081

*VHH antibody (His tag), Isotype Control*	Hedgehog	Others
VHH antibody (His tag), Isotype Control is a His-conjugated recombinantly expressed antibody that does not bind to the target and serves as a negative control for VHH nanobodies.

HY-W039953

Ac4GlcNAz N-azidoacetylglucosamine-tetraacylated	Biochemical Assay Reagents	Others
Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated) is an azido-tagged analogue of N-acetylglucosamine (GlcNAC). It features azide functionality on the N-acyl side chain and is acetylated to aid in cell membrane permeation. Once in the cell, the acetylated compound is deprotected and takes part in the hexosamine biosynthetic pathway by action of GlcNAc kinase. The resulting modified proteins are detected by the addition of fluorescent tags under Cu(I)-catalyzed azide-alkyne cycloaddition conditions.

HY-136849

TL13-68	Src FGFR Ribosomal S6 Kinase (RSK) LIM Kinase (LIMK) MAP3K	Others
TL13-68 is a biotin-tagged version of SM1-71, and it can be used to research the mechanism of SM1-71 .

HY-N13916

Alternaric acid	Fungal	Infection
Alternaric acid is a host-specific toxin produced by the plant fungal. In the presence of Ca ²⁺ and Mg ²⁺, Alternaric acid stimulates phosphorylation of His-tagged cytosolic kinase RiCDPK2 .

HY-150411

Cys-C-cGMP	AUTACs	Cancer
Cys-C-cGMP is a autophagy tag for AUTACs. Cys-C-cGMP can increase the K63-linked ubiquitination of mitochondria in HeLa cells .

HY-153887

HyT36(-Cl)	EGFR	Others
HyT36(-Cl) is the inactive control compound of HyT36, a small molecule hydrophobic tag compound that can be used in protein folding research .

Cat. No.	Product Name

HY-L091

Lipid Metabolism Compound Library

799 compounds

Lipids are a fundamental class of organic molecules implicated in a wide range of biological processes, and based on this can be broadly classified into five categories: fatty acids, triacylglycerols (TAGs), phospholipids, sterol lipids and sphingolipids. Lipids play a crucial role in different metabolic pathways and cellular functions. Lipid metabolism is an important physiological process that is related to nutrient adjustment, hormone regulation, and homeostasis. Lipid metabolism dysregulation is associated with many diseases such as obesity, liver disease, aging and inflammation.

MCE offers a unique collection of 799 compounds related to lipid metabolism, which target relevant targets in the process of lipid metabolism, such as ATGL, MAGL, FAAH, acetyl-Coa Carboxylase, FASN, etc. MCE lipid metabolism compound library is a useful tool for research lipid metabolism and drug discovery of diseases related to lipid metabolism.

HY-L918

Molecular Glue-like Compound Library

320 compounds

Targeted Protein Degradation (TPD) is a novel and promising approach to drug development. It shows great potential for targeting proteins traditionally considered "undruggable" due to the lack of enzymatic function and absence of binding sites by tagging them for degradation or recruiting natural degradation mechanisms.

Molecular glues are a type of small-molecule degraders that primarily induce novel interactions between E3 ubiquitin ligases and target proteins, forming ternary complexes that lead to protein ubiquitination and subsequent proteasomal degradation. Compared with PROTACs, molecular glues generally have lower molecular weights, higher cell permeability, and better drug-like properties. Additionally, the design of molecular glues is relatively simple, without the requirements for complex linkers and ligand optimization. As a result, molecular glues have gradually emerged as a promising therapeutic approach for various diseases.

Multiple types of molecular glues have been reported previously. Analysis of co-crystal complex structures reveals that CRBN-related molecular glues are more versatile. Therefore, MCE researchers select active molecules related to these targets as probes for artificial intelligence (AI) screening.Subsequently, molecular docking technology was used to verify whether the screened molecules retained the key pharmacophore features. Ultimately, we obtained 320 molecular glue analogs, and these compounds serve as powerful tools for the research of molecular glues.

Cat. No.	Product Name	Type

HY-D2270

*Halo tag* TMR**	Fluorescent Dyes/Probes
Halo tag TMR is a red fluorescent dye composed of Halo tag ligand molecules and TMR. Halo tag can quickly and stably covalently bind to Halo protein with high specificity and affinity .

HY-D0021

Ethidium bromide 10+ Cited Publications EtBr; Homidium bromide	Fluorescent Dyes/Probes
Ethidium bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.

HY-136936

PYBG-BODIPY	Fluorescent Dyes/Probes
PYBG-BODIPY is a dye and has a role as a fluorochrome. PYBG-BODIPY specifically and efficiently labels the target genetically encoded SNAP-tags in live cells .

HY-D1621

3-NBD-C12 Cholesterol	Fluorescent Dyes/Probes
C-12 NBD cholesterol is a cholesterol derivative with a hydrophilic fluorophore tag (NBD: Ex=465 nm, Em=535 nm). C-12 NBD cholesterol can be used to study the utilization and metabolism of cholesterol .

HY-D1033

Biotin-tagged KR-33493

Dyes

Biotin-tagged KR-33493 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-D2183

6-Carboxy-JF5252	Fluorescent Dyes/Probes
6-Carboxy-JF5252 is a fluorophore. 6-Carboxy-JF5252 can be used as probes, dyes, tags. 6-Carboxy-JF5252 can be used for the research of super-resolution imaging .

HY-D1386

JF526-Taxol TFA	Fluorescent Dyes/Probes
JF526-Taxol (TFA) is a versatile scaffold for fluorogenic probes including ligands for self-labeling tags, stains for endogenous structures, and spontaneously blinking labels for super-resolution immunofluorescence .

HY-D1579

C12 NBD Globotriaosylceramide	Fluorescent Dyes/Probes
C12 NBD galactosylceramide is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide has been used to detect ceramide trihexoside .

HY-145493

C12 NBD Galactosylceramide	Fluorescent Dyes/Probes
C12 NBD galactosylceramide, fluorescent dye, is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide can be used for the research of imaging .

HY-D1749

C6 NBD L-threo-ceramide	Fluorescent Dyes/Probes
C6 NBD L-threo-ceramide is a cell-permeable analog of ceramides that is tagged with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD). It is rapidly transferred between liposomes, labels the Golgi apparatus, and is metabolized to C6 NBD sphingomyelin in BHK cells and V79 fibroblasts.

HY-D1575

C6 NBD Galactosylceramide	Dyes
C6 NBD galactosylceramide is an active derivative of galactosylceramide that is tagged with fluorescent C6 nitrobenzoxadiazole (C6 NBD). C6 NBD galactosylceramide can be used as a substrate for neutral β-glycosylceramidase (GCase) to study intracellular localization and metabolism of galactosylceramide (Ex=nm, Em=525) .

HY-D1584

C12 NBD Sphingomyelin	Fluorescent Dyes/Probes
C12 NBD sphingomyelin is an active derivative of sphingomyelin (HY-113498) that is tagged with fluorescent C12 nitrobenzoxadiazole (C12 NBD). C12 NBD sphingomyelin can be used as a sphingomyelinase substrate for studying the metabolism and transport of sphingomyelins (Ex=470 nm, Em=525 nm) .

HY-136937

PYBG-TMR	Fluorescent Dyes/Probes
PYBG-TMR is a dye and has a role as a fluorochrome. PYBG-TMR specifically and efficiently labels the target genetically encoded SNAP-tags in live cells . PYBG-TMR is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D2480

BODIPY 480/508-cholesteryl linoleate	Fluorescent Dyes/Probes
BODIPY 480/508-cholesteryl linoleate is a cell-permeable and fluorescently tagged derivative of Cholesteryl Linoleate (HY-W010697). BODIPY 480/508-cholesteryl linoleate has been used to monitor cholesterol trafficking in isolated human monocyte-derived macrophages (Ex/Em=480/508 nm).

HY-133535

PA Janelia Fluor® 646, SE

PA-JF646-NHS

Dyes

PA Janelia Fluor® 646, SE (PA-JF646-NHS), a photoactivatable fluorescent dye, is an NHS ester for coupling to primary amine groups. PA-JF646-NHS is non-fluorescent until activated at 365 nm. NHS ester can be converted to relevant substrate for use in self-labeling tag systems, e.g.HaloTag ^® and SNAP-tag ^®. PA-JF646-NHS is used for single molecule tracking and super resolution microscopy in live cells, specifically live cell sptPALM and fixed cell PALM. (λ_{Excitation/emission}~650/664 nm). Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D1690

sBADA TFA	Fluorescent Dyes/Probes
sBADA TFA is a potent green fluorescent dye. sBADA TFA is a sulfonated BODIPY-FL 3-amino-D-alanine. sBADA TFA is used to label peptidoglycans in bacterial cell walls in situ. (λ_ex=490 nm, λ_em=510 nm) .

HY-131028

Janelia Fluor® 646 TFA JF646 TFA	Fluorescent Dyes/Probes
Janelia Fluor® 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-138658

Janelia Fluor® 526, SE

JF526, SE; JF526, NHS

Fluorescent Dyes/Probes

Janelia Fluor 526, SE (JF526,SE) is a fluorogenic yellow fluorescent dye that contains NHS ester group. JF526 is a versatile scaffold for fluorogenic ligands, including labels for genetically encoded self-labeling protein tags and stains for endogenous structures . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-D2327

DPP-8/9 probe-1	Fluorescent Dyes/Probes
DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC₅₀ of 210 nM and 15 nM, respectively) .

HY-D1506

Fl-DIBO

Dyes

Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W800838

BP Fluor 488 Tetrazine

Fluorescent Dyes/Probes

BP Fluor 488 Tetrazine is a bright, green-fluorescent probe used for detection TCO-tagged biopolymers. BP Fluor 488 Tetrazine demonstrates exceptionally fast cycloaddition kinetics (up to 30 000 M-1 s-1) with trans-cyclooctenes (TCO) as the dienophile, the fastest kinetics ever reported for any bioorthogonal reaction. In applications such as in vivo cancer imaging or pre?targeted cell labeling studies where rapid reaction kinetics is a must BP Fluor 488 Tetrazine probe would of great value.

HY-W800696

BP Fluor 430 azide

Fluorescent Dyes/Probes

BP Fluor 430 Azide is a water-soluble, green-fluorescent, azide-activated probe that reacts with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free click chemistry reaction to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. BP Fluor 430 is a bright, photostable, green-fluorescent probe with excitation near its absorption maximum at 432 nm and emission maximum at 539 nm. This probe is water soluble and pH-insensitive from pH 4 to pH 10. A next generation probe, BP Fluor 430 Picolyl Azide, is also available for detection of low abundance alkyne-tagged biomolecules.

HY-W800701

BP Fluor 546 DBCO

Fluorescent Dyes/Probes

BP Fluor 546 DBCO is an azide-reactive probe that can be used for imaging azide-tagged biomolecules via a copper-free click reaction. The DBCO moiety reacts with azides to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, BP Fluor 546 DBCO is an ideal alternative to copper-requiring fluorescent alkynes. BP Fluor 546 is a water-soluble, pH-insensitive (from pH 4-10), orange-fluorescent dye with absorption and emission maxima at 554 and 570 nm, respectively. It can be used with the 488 nm and 532 nm laser lines. BP Fluor 546 dye conjugates to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, which are often used for generating stable signals in imaging and flow cytometry.

Cat. No.	Product Name	Type

HY-P3152

Streptavidin 2 Publications Verification	Native Proteins
Streptavidin is a ～60 kDa homotetramer. Streptavidin binds four molecules of biotin with the highest affinity. The binding affinity of biotin to streptavidin is one of the highest reported for a non-covalent interaction to date, with a K_D ～ 0.01 pM . Streptavidin has an immunosuppressive role .

HY-W039921

2-[(Azidoacety)amino]-2-deoxy-D-galactose N-Azidoacetylgalactosamine; GalNAz	Carbohydrates
2-[(Azidoacety)amino]-2-deoxy-D-galactose targets O-GlcNAc-modified proteins. By detecting and targeting O-GlcNAc-modified proteins, 2-[(Azidoacety)amino]-2-deoxy-D-galactose can serve as a chemical tag for intracellular sugar chain metabolism .

HY-172504

DSPE-PEG5000-KAA	Drug Delivery
DSPE-PEG5000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG5000-KAA can be used for drug delivery .

HY-172502

DSPE-PEG1000-KAA	Drug Delivery
DSPE-PEG1000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG1000-KAA can be used for drug delivery .

HY-172503

DSPE-PEG2000-KAA	Drug Delivery
DSPE-PEG2000-KAA is a PEG compound which composed of DSPE and a CKAAKNK peptide (KAA). KAA specifically binds to tumor vessels in RIP-Tag2 transgenic mice. DSPE-PEG2000-KAA can be used for drug delivery .

HY-126944

2-Aminobenzanilide 2-Amino-N-phenylbenzamide	Indicators
2-Aminobenzamide is a neutral and stable compound used as fluorescent tag, numerously in Glycan analysis. 2-aminobenzamide acts as the starting material for several important reactions like Bargellini reaction as an competent ambident nucleophile. Specifically 2-aminobenzamide and its derivatives are used in the blood coagulation cascade .

HY-157916

ARP Aldehyde reactive probe	Indicators
ARP (Aldehyde reactive probe) is an aldehyde reactive probe for detecting abasic site (common DNA lesions and intermediates in mutagenesis and carcinogenesis) in DNA, which specificially tags AP site with biotin residues. ARP is highly sensitive with a femtomolar-level basic site detection capabilities (less than one site per 10 ⁴ nucleotides) .

Cat. No.	Product Name	Target	Research Area

HY-P0327

*T7 Tag* Peptide** 1 Publications Verification	Biochemical Assay Reagents	Others
T7 Tag Peptide is a protein tag derived from the N-terminal 11 residues of the major T7 capsid protein, gp 10. T7 Tag Peptide can be used in different immunoassays as well as affinity purification .

HY-P0327A

*T7 Tag* Peptide TFA** 1 Publications Verification	Peptides	Others
T7 Tag Peptide TFA is a protein tag derived from the N-terminal 11 residues of the major T7 capsid protein, gp 10. T7 Tag Peptide TFA can be used in different immunoassays as well as affinity purification .

HY-P10531

ALFA-tag	Peptides	Others
ALFA-tag is a small and stable α-helical structure composed of 15 amino acids. ALFA-tag is highly hydrophilic and can be placed at the N-terminus, C-terminus, or between two independently folded domains of the target protein without affecting the function of the protein. ALFA-tag is widely used as an epitope tag and is used for the detection and manipulation of proteins in living cells .

HY-P0325

*V5 Epitope Tag* Peptide TFA**	Peptides	Others
V5 Epitope Tag Peptide (TFA) is a tag peptide derived from a small epitope present on the P and V proteins of the paramyxovirus of simian virus 5.

HY-P0329

*X-press Tag* Peptide**	Peptides	Others
X-press Tag Peptide is a tag peptide used for protein purification. X-press Tag is also an N-terminal leader peptide; this N-terminal peptide contains a polyhistidine sequence, the Xpress epitope (part of bacteriophage T7 gene 10 protein) and an enterokinase cleavage site. Anti-Xpress antibodies recognize the Xpress epitope sequence found in this leader peptide.

HY-P0326

*S Tag* Peptide**	Peptides	Others
S Tag Peptide is a 15 amino acid peptide derived from RNase A.

HY-P0294

Hexa-His 6X His Tag	Biochemical Assay Reagents	Others
Hexa-His (6X His Tag) is a commonly used affinity tag made up of six histidine residues. HEXA-HIS can bind to affinity chromatography media containing transition metal ions like nickel (Ni ²⁺) or cobalt (Co ²⁺), making it useful for protein purification .

HY-P5969

Cys-V5 Peptide	Biochemical Assay Reagents	Others
Cys-V5 Peptide, a tag peptide, is the V5 Peptide with an N-terminal cysteine. Cys-V5 Peptide can be used to label proteins

HY-P3738

Osteocalcin (7-19) (human)	Biochemical Assay Reagents	Others
Osteocalcin (7-19) (human) is a peptide fragment of Osteocalcin, can be used as a peptide tag.

HY-P3763

Atrial Natriuretic Peptide (7-28), human, canine	Natriuretic Peptide Receptor (NPR)	Cardiovascular Disease
Atrial Natriuretic Peptide (7-28), human, canine is a peptide fragment of atrial natriuretic peptide, can be used as a peptide tag .

HY-P0239

HA Peptide 5+ Cited Publications	Influenza Virus	Inflammation/Immunology
HA Peptide (HA tag) is a nine amino acids peptide derived from the human influenza hemagglutinin (HA). HA Peptide is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry.

HY-P0223

FLAG peptide Maximum Cited Publications 18 Publications Verification	Biochemical Assay Reagents	Inflammation/Immunology
FLAG peptide is a multifunctional fusion tag for the purification of recombinant proteins. FLAG peptide maintances the natural folding of its fusing proteins. FLAG peptide can be removed by enterokinase, and eluted under non-denaturing conditions .

HY-P0319

3X FLAG peptide 5+ Cited Publications	Biochemical Assay Reagents	Others
3X FLAG peptides are FLAG-tagged peptides containing three repeats of the Asp-Tyr-Lys-Xaa-Xaa-Asp motif. 3X FLAG peptide can be used for protein separation and purification, and competitive elution with target proteins.

HY-P3332A

*3x DYKDDDDK Tag* TFA**	Biochemical Assay Reagents	Others
DYKDDDDK peptide (FLAG) is a useful tool for investigating the function and localization of proteins whose antibodies (Abs) are not available. Often it is also used in a 3X FLAG format (3x DYKDDDDK Tag TFA) for purifying difficult proteins that accumulate in low abundance .

HY-P10900

*2x HA tag* peptide**	Peptides	Others
2x HA tag peptide is a tag peptide (YPYDVPDYAYPYDVPDYA) with a hemagglutinin HA tag. 2x HA tag peptide is often used to be fused to the 5' end of the target protein to label the protein .

HY-P2467

Biotin-TAT (47-57)	Fluorescent Dye	Metabolic Disease
Biotin-TAT (47-57), a biotin tagged TAT, is a transactivator of transcription. Biotin-TAT (47-57) is one of the most widely used protein transduction domains (PTDs) into different primary cells is ATP- and temperature-dependent, indicating the involvement of endocytosis .

HY-P1509

Rhodopsin Epitope Tag	Peptides	Neurological Disease
Rhodopsin Epitope Tag is a 9-amino acid peptide localized within the C-terminal region of bovine rhodopsin . Rhodopsin Epitope Tag is widely used as an epitope tag and can be recognized by a number of anti-rhodopsin antibodies.

HY-P5491

3X HA Tag	Peptides	Others
3X HA Tag is a biological active peptide. (This tag peptide may be used to detect proteins and peptides, and to facilitate functional analysis of proteins of interest.)

HY-P3332

3x DYKDDDDK Tag	Biochemical Assay Reagents	Others
3x DYKDDDDK Tag is a useful tool for investigating the function and localization of proteins whose antibodies (Abs) are not available. Often it is also used in a 3X FLAG format (3x DYKDDDDK Tag) for purifying difficult proteins that accumulate in low abundance .

HY-P10632

HiBiT tag	Peptides	Others
HiBiT tag is a complimentary peptide (VSGWRLFKKIS), with high affinity for LgBiT. HiBiT tag is fused to the Gβ subunit of the receptor. The complementation of LgBiT and HiBiT facilitates the stabilization of ETR and G protein. HiBiT is attached to a protein of interest (GFP) to quantify transport to the cytosol .

HY-P10633

SmBiT Tag	Peptides	Others
SmBiT Tag is an 11 amino acid complementary peptide (VTGYRLFEEIL), with low affinity for LgBiT .

HY-P5758

His 11	Peptides	Others
His11 is consists of a contiguous series of amino acid residues. His11 can be used as a tag peptide .

HY-P5758A

His 11 TFA	Peptides	Others
His11 TFA is consists of a contiguous series of amino acid residues. His11 TFA can be used as a tag peptide .

HY-P1877

SV40 T-Ag-derived NLS peptide	Peptides	Cancer
SV40 T-Ag-derived NLS peptide is a nuclear localization signal DNA tagged to this peptide efficiently translocates into the cell nucleus .

HY-P1877A

SV40 T-Ag-derived NLS peptide TFA	Peptides	Cancer
SV40 T-Ag-derived NLS peptide TFA is a nuclear localization signal DNA tagged to this peptide efficiently translocates into the cell nucleus .

HY-P2546

Biotin-Substance P	Neurokinin Receptor	Neurological Disease
Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .

HY-P0319A

3X FLAG peptide TFA 5+ Cited Publications	Peptides	Others
3X FLAG peptide TFA is a FLAG-tagged peptide containing three repeats of the Asp-Tyr-Lys-Xaa-Xaa-Asp motif. 3X FLAG peptide TFA can be used for protein separation and purification, and competitive elution with target proteins.

HY-P3908

FITC-β-Ala-Amyloid β-Protein (1-42) ammonium	Amyloid-β	Neurological Disease
FITC-β-Ala-Amyloid β-Protein (1-42) ammonium is a FITC tagged Aβ1-42 monomer peptide. Aβ1-42 plays a key role in the pathogenesis of Alzheimer’s disease .

HY-P0110

(Iso)-Z-VAD(OMe)-FMK (Iso)-Z-Val-Ala-Asp(OMe)-FMK	Caspase	Cancer
(Iso)-Z-VAD(OMe)-FMK ((Iso)-Z-Val-Ala-Asp(OMe)-FMK) is an isomer of the caspase and UCHL1 inhibitor Z-VAD(OMe)-FMK (HY-16658) .

HY-P5314

OK2	EGFR STAT	Others
OK2, a specific inhibitor of the CCN2/EGFR interaction, efficiently blocks CCN2/EGFR interaction through binding to the CT domain of CCN2. OK2 can be used for kidney fibrosis and chronic kidney disease research .

HY-125586

β-Amanitin	DNA/RNA Synthesis ADC Cytotoxin	Cancer
β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .

HY-P0312

c-Myc Peptide TFA 1 Publications Verification	c-Myc	Cancer
c-Myc Peptide (TFA) is a synthetic peptide corresponding to the C-terminal amino acids (410-419) of human c-myc protein, and participates in regulation of growth-related gene transcription.

HY-W480799

H-Gly-Gly-Tyr-OH	Biochemical Assay Reagents	Others
H-Gly-Gly-Tyr-OH is a tripeptide that plays an important role in various biochemical applications. H-Gly-Gly-Tyr-OH can be used in the fields of pharmaceuticals and biochemistry .

HY-P0328

*VSV-G tag* Peptide**	VSV	Infection
VSV-G Peptide is a 11 amino acid peptide derived from the Vesicular Stomatitis viral glycoprotein.

HY-P0223A

FLAG peptide TFA Maximum Cited Publications 18 Publications Verification	Biochemical Assay Reagents	Others
FLAG peptide TFA is the TFA salt form of FLAG peptide (HY-P0223). FLAG peptide TFA is a multifunctional fusion tag for the purification of recombinant proteins. FLAG peptide TFA maintances the natural folding of its fusing proteins. FLAG peptide TFA can be removed by enterokinase, and eluted under non-denaturing conditions .

HY-P10714

Ub4ix	Proteasome Apoptosis Deubiquitinase	Cancer
Ub4ix is a DUB/26S proteasome inhibitor. Ub4ix can protect K48-linked Ub chains from being chopped up by deubiquitinating enzymes (DUBs) and prevent the proteasomal degradation of Ub-tagged proteins. Ub4ix can reduce the viability of Hela cells and induce apoptosis, with an IC₅₀ value of 1.6 μM .

HY-P5947

Tat-HA-NR2B9c	HIV	Neurological Disease
Tat-HA-NR2B9 contains a fragment of the cellmembrane transduction domain of HIV-1 Tat, a influenza virus hemagglutinin (HA) epitope-tag, and the C-terminal 9 amino acids of NR2B (NR2B9c). Tat-HA-NR2B9 reduces infarct size and improves neurological functions in ischemia-induced cerebral injury in the rats

HY-P5222

Angio-S	Peptides	Others
Angio-S is a bioactive peptide and has been reported used as a cosmetic ingredient .

HY-P5479

EE epitope	Peptides	Others
EE epitope is a biological active peptide. (This peptide is a 314 to 319 amino acids fragment of the middle T antigen of mouse polymavirus. Glu-Glu epitope peptide is widely used as an epitope tag.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)

HY-P1047

β-Sheet Breaker Peptide iAβ5 [Pro18, Asp21] β-Amyloid (17-21)	Amyloid-β	Neurological Disease
β-Sheet Breaker Peptide iAβ5 is an effective brain amyloid-β (Abeta) degrader. Abeta deposits are associated with Alzheimer's disease (AD), and the related toxicity arises from its β-sheet conformation and aggregation. β-Sheet Breaker Peptide iAβ5 can repeatedly induce the degradation of fibrillary amyloid deposits in vivo. Therefore, β-Sheet Breaker Peptide iAβ5 can prevent and/or reverse neuronal contraction caused by Abeta and reduce the range of interleukin IL-1beta positive microglial-like cells around Abeta deposits. β-Sheet Breaker Peptide iAβ5 can reduce the size and/or number of brain amyloid plaques in AD. β-Sheet Breaker Peptide iAβ5 is labeled with a hydrophobic benzyl alcohol (HBA) tag and shows a bright blue color under acidic conditions, which can be used for quantitative determination.

Cat. No.	Product Name

HY-K0239

*Strep-Tag* Ⅱ Agarose**
MCE Strep-Tag Ⅱ Agarose can be used for the detection and purification of Strep-tag Ⅱ and Twin Strep-tag Ⅱ proteins from various expression sources.

HY-K0210

*Ni-NTA His-Tag* Purification Agarose** 10+ Cited Publications
MCE Ni-NTA His-Tag Purification Agarose, a 6% highly cross-linked agarose reagent, enables high-yield, high-purity purification of his-tagged proteins.

HY-K0207

Anti-Flag Magnetic Beads Maximum Cited Publications 129 Publications Verification
MCE Anti-Flag Magnetic Beads are used for immunoprecipitation (IP) of specific Flag-tagged (DYKDDDDK) proteins expressed in bacterial and mammalian cells and in vitro expression systems, and also suitable for Co-immunoprecipitation and purification of Flag-tagged protein.

HY-K0235

Anti-YFP Affinity Gel
MCE Anti-YFP Affinity Gel can be used for the detection and purification of proteins tagged with GFP and EGFP and IP assays.

HY-K0221

Affinity Chromatography Column 1 Publications Verification
MCE Affinity Chromatography (AC) Columns are designed for purification of recombinant proteins with different tags, enzymes, antibodies, antigens and nucleic acids.

HY-K0240

Ni-IDA Magnetic Agarose Beads
MCE Ni-IDA Magnetic Agarose Beads can be used for the detection and purification of His-tag proteins from various expression sources.

HY-K0241

Ni-NTA Magnetic Agarose Beads 1 Publications Verification
MCE Ni-NTA Magnetic Agarose Beads can be used for the detection and purification of His-tag proteins from various expression sources.

HY-K0211

Glutathione Agarose 5 Publications Verification
MCE Glutathione Agarose, a 4% highly cross-linked agarose reagent, enables high-yield, high-purity purification of GST-tagged proteins.

HY-K0201

Anti-HA Magnetic Beads 80+ Cited Publications
MCE Anti-HA Magnetic Beads are used for immunoprecipitation (IP) of specific HA-tagged proteins expressed in bacterial and mammalian cells and in vitro expression systems.

HY-K0238

Ni-IDA Agarose
MCE Ni-IDA Agarose can be used for the detection and purification of His-tag proteins.

HY-K0222

Anti-GST Magnetic Beads 10+ Cited Publications
MCE Anti-GST Magnetic Beads are used for immunoprecipitation (IP) of specific GST-tagged proteins expressed in bacterial and mammalian cells and in vitro expression systems.

HY-K0209

Anti-His Magnetic Beads 5+ Cited Publications
MCE Anti-His Magnetic Beads are used for immunoprecipitation (IP) of specific His-tagged proteins expressed in bacterial and mammalian cells and in vitro expression systems.

HY-K0206

Anti-c-Myc Magnetic Beads 40+ Cited Publications
MCE Anti-c-Myc Magnetic Beads are used for immunoprecipitation (IP) of specific c-Myc-tagged proteins expressed in bacterial and mammalian cells and in vitro expression systems.

HY-K0217

Anti-Flag Affinity Gel 2 Publications Verification
MCE Anti-Flag Affinity Gel is used for immunoprecipitation (IP) or protein purification of specific Flag-tagged (DYKDDDDK) proteins expressed in bacterial and mammalian cells and in vitro expression systems.

HY-K0220

Ni-NTA 6FF Prepacked Column 1 Publications Verification
MCE Ni-NTA 6FF Prepacked Column is ideal for high performance purification of polyhistidine-tagged proteins expressed in E.coli, yeast, insect and mammalian expression systems.

HY-K0201A

Anti-HA Magnetic Beads (1 μm) 1 Publications Verification
MCE Anti-HA Magnetic Beads (1 μm) are used for immunoprecipitation (IP) of specific HA-tagged proteins expressed in bacterial and mammalian cells andin vitro expression systems.

HY-K0206A

Anti-c-Myc Magnetic Beads (1 μm) 2 Publications Verification
MCE Anti-c-Myc Magnetic Beads (1 μm) are used for immunoprecipitation (IP) of specific c-Myc-tagged proteins expressed in bacterial and mammalian cells and in vitro expression systems.

HY-K0247

ConA Magnetic Beads
MCE ConA Magnetic Beads can be used to isolate cells or purify glycoproteins from serum and cell extracts. It is also employed in experiments such as collecting and immobilizing cell nuclei, CUT & Run, and CUT & Tag.

HY-K0234

Glutathione Magnetic Agarose Beads 1 Publications Verification
MCE Glutathione Magnetic Agarose Beads have high protein-binding capacity and stability, making it ideal for high performance purification of GST-tagged fusion proteins expressed in E. coli, yeast, insect and mammalian expression systems.

Cat. No.	Product Name	Target	Research Area

HY-P99732

Minretumomab CC-49	Mucin	Cancer
Minretumomab (CC-49) is a murine monoclonal antibody against *TAG-72* (tumor-associated glycoprotein 72). Minretumomab is used in cancer and immunity research .

HY-P99759

*Nogapendekin alfa (his tag)* IL-15N72D	Interleukin Related	Inflammation/Immunology Cancer
Nogapendekin alfa (his tag), a soluble protein subunit of a human interleukin (IL)-15 variant, is a superagonist of IL-15. Nogapendekin alfa (his tag) promotes the proliferation and viability of immune cells. Nogapendekin alfa (his tag) combines with Inbakicept (HY-P99661) at a ratio of 2:1, to form N-803 (Nogapendekin alfa inbakicept), an IL-15 cytokine antibody fusion protein. N-803 reduces tumor burden by activation of NK cells and CD8 ⁺ T cells .

HY-P99764

Odesivimab REGN-3471	Filovirus	Infection
Odesivimab is a human monoclonal antibody, targeting Ebola virus glycoprotein with a K_D value of 7.74 nM for recombinant histidine-tagged Makona strain Ebola virus glycoprotein ectodomain protein. Odesivimab can be used in research of Ebola virus infection .

HY-P990683

Satumomab	Inhibitory Antibodies	Inflammation/Immunology
Satumomab is an anti-TAG-72 IgG4-G2a κ monoclonal antibody .

HY-P991081

*VHH antibody (His tag), Isotype Control*	Hedgehog	Others
VHH antibody (His tag), Isotype Control is a His-conjugated recombinantly expressed antibody that does not bind to the target and serves as a negative control for VHH nanobodies.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P0239

HA Peptide 5+ Cited Publications	Natural Products Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Influenza Virus
HA Peptide (HA tag) is a nine amino acids peptide derived from the human influenza hemagglutinin (HA). HA Peptide is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry.

HY-N15358

15:0-18:1 DG	Structural Classification Natural Products Source classification Endogenous metabolite	Drug Metabolite
15:0-18:1 DG is a type of diacylglycerol (DAG). 15:0-18:1 DG can be produced by hydrolysis of triacylglycerol (TAG) in butter fat. 15:0-18:1 DG is promising for research of obesity, cardiovascular diseases, and dietary interventions .

HY-N6707

Triacsin C 3 Publications Verification WS 1228A; FR 900190	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Parasite
Triacsin C (WS 1228A), is an orally active and intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, which can be isolated from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity . Triacsin C exhibits highly inhibitory effect against rotavirus replication .

HY-N13916

Alternaric acid	Structural Classification Natural Products Microorganisms Source classification	Fungal
Alternaric acid is a host-specific toxin produced by the plant fungal. In the presence of Ca ²⁺ and Mg ²⁺, Alternaric acid stimulates phosphorylation of His-tagged cytosolic kinase RiCDPK2 .

Cat. No.	Product Name	Chemical Structure

HY-15121S1

L-Theanine-13C2,15N2
L-Theanine-13C2,15N2yes ¹³C₂, ¹⁵N₂Tagged L-Theanine (HY-15121).

Cat. No.	Product Name		Classification

HY-139163

BGSN3		Azide
BGSN3 is a good substrate for the SNAP-tag ^? and H ⁵ enzymes. The activities of SNAP-tag ^? and H ⁵ enzymes on BGSN3 are reasonable (IC₅₀=17.8 and 10 μM, respectively) . BGSN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-139162

BGN3		Azide
BGN3 is a good substrate for the SNAP-tag ^? and H ⁵ enzymes. The activities of SNAP-tag ^? and H ⁵ enzymes on BGN3 are reasonable (IC₅₀= 15.6 and 23.5 μM, respectively) . BGN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-147097A

EDA-DA TFA		Alkynes
EDA-DA is a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. EDA-DA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-W039953

Ac4GlcNAz N-azidoacetylglucosamine-tetraacylated		Azide
Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated) is an azido-tagged analogue of N-acetylglucosamine (GlcNAC). It features azide functionality on the N-acyl side chain and is acetylated to aid in cell membrane permeation. Once in the cell, the acetylated compound is deprotected and takes part in the hexosamine biosynthetic pathway by action of GlcNAc kinase. The resulting modified proteins are detected by the addition of fluorescent tags under Cu(I)-catalyzed azide-alkyne cycloaddition conditions.

HY-164745

L-β-Ethynylserine		Alkynes
L-β-ethynylserine (βES) is a threonine analog. L-β-ethynylserine is efficiently incorporated into newly synthesized proteins, and allows their selective visualization or enrichment through bioorthogonal ligation to fluorescent dyes or affinity tags, respectively.

HY-151645

Alkyne-SNAP		Labeling and Fluorescence Imaging Alkynes
Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation .

HY-159493

BI2536-PEG2-Halo		Azide
BI2536-PEG2-Halo is a bifunctional molecule containing a ligand for Halo tag and a Polo-like kinase 1 (PLK1) inhibitor BI-2536 (HY-50698). BI2536-PEG2-Halo inhibits the proliferation of 293T cells with Halo-p53R273H(FL)-mCherry tag (IC₅₀=23 nM), exhibits selective toxicity against p53 mutant cancer cells .

HY-151646

Alkyne-PEG5-SNAP Alkyne-PEG5-BG		Alkynes Labeling and Fluorescence Imaging
Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation . Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-147097

EDA-DA		Alkynes
EDA-DA, a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. Peptidoglycan (PG), an essential structure in the cell walls of the vast majority of bacteria, is critical for division and maintaining cell shape and hydrostatic pressure . EDA-DA is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W039924

N-Azidoacetylmannosamine		Azide
N-Azidoacetylmannosamine is an azide-labeled sugar that can be metabolically incorporated into glycoproteins. N-Azidoacetylmannosamine can then react with alkynes or phosphines that are linked to fluorescent or biotin tags for visualization or capture of the glycoproteins. N-Azidoacetylmannosamine can be used for studying glycan structures and functions in vivo .

HY-W039921

2-[(Azidoacety)amino]-2-deoxy-D-galactose N-Azidoacetylgalactosamine; GalNAz		Azide
2-[(Azidoacety)amino]-2-deoxy-D-galactose targets O-GlcNAc-modified proteins. By detecting and targeting O-GlcNAc-modified proteins, 2-[(Azidoacety)amino]-2-deoxy-D-galactose can serve as a chemical tag for intracellular sugar chain metabolism .

HY-136205

IA-Alkyne Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide		Alkynes
IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection . IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling . IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-101460

Tz-Thalidomide		Tetrazine
Tz-Thalidomide is a tetrazine tagged Thalidomide (HY-14658) (Ligands for E3 Ligase). Tz-Thalidomide has binding affinity for BRD4, with IC₅₀s of 46.25 μM (BRD4-1) and 62.55 μM (BRD4-2). Tz-Thalidomide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups .

HY-D1506

Fl-DIBO		Labeling and Fluorescence Imaging
Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1597

Cyanine3.5 azide chloride		Azide
Cyanine3.5 azide chloride, an analog of Cyanine3.5 azide, is a potent green fluorescent dye. Cyanine3.5 azide chloride uses click chemistry to tag the ethylidene group. (λ_ex=591 nm, λ_em=604 nm) . Cyanine3.5 azide (chloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151787

Fmoc-L-Lys(N3-Aca-DIM)-OH		Azide
Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151786

Fmoc-L-Lys(Pentynoyl-DIM)-OH		Alkynes Azide
Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

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