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Results for "

semi-synthetic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (1) Akt (3) Amyloid-β (2) Antibiotic (122) Apoptosis (14) Autophagy (5) Bacterial (121) Beta-lactamase (7) Biochemical Assay Reagents (2) Calcium Channel (7) Cannabinoid Receptor (2) CDK (1) Chloride Channel (2) CMV (2) DNA/RNA Synthesis (4) Drug Derivative (3) Drug Intermediate (3) Drug Metabolite (1) ERK (1) Fungal (7) GABA Receptor (4) HIF/HIF Prolyl-Hydroxylase (8) HIV (4) Isotope-Labeled Compounds (16) LXR (1) MDM-2/p53 (7) MEK (1) Microtubule/Tubulin (9) mTOR (4) P-glycoprotein (2) Parasite (10) Penicillin-binding protein (PBP) (17) Potassium Channel (7) PPAR (3) Prostaglandin Receptor (2) PTEN (2) Raf (1) Ras (1) Reactive Oxygen Species (ROS) (2) Reference Standards (41) Topoisomerase (5)
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Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0525A

Carbenicillin disodium 5 Publications Verification Sodium carbenicillin	Antibiotic Bacterial	Infection
Carbenicillin disodium (Sodium carbenicillin) is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin disodium can interfere the cell wall synthesis while displaying low toxicity to plant tissue .

HY-B0974

Methicillin sodium salt 5 Publications Verification Meticillin sodium	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation .

HY-15459

Cabazitaxel 15+ Cited Publications XRP6258; RPR-116258A; taxoid XRP6258	Microtubule/Tubulin Autophagy	Cancer
Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-111533

Ingenol 3-Hexanoate	Drug Derivative HIV	Cancer
Ingenol 3-Hexanoate, an ingenol semi-synthetic derivative, is a potent anticancer agent. Ingenol 3-Hexanoate can be used in research of cancer .

HY-B0525

Carbenicillin	Antibiotic Bacterial	Infection
Carbenicillin is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin can interfere the cell wall synthesis while displaying low toxicity to plant tissue .

HY-B0525AR

Carbenicillin disodium (Standard) Sodium carbenicillin (Standard)	Reference Standards Antibiotic Bacterial	Infection
Carbenicillin (disodium) (Standard) is the analytical standard of Carbenicillin (disodium). This product is intended for research and analytical applications. Carbenicillin disodium (Sodium carbenicillin) is a broad-spectrum semi-synthetic penicillin antibiotic for gram-negative bacteria. Carbenicillin disodium can interfere the cell wall synthesis while displaying low toxicity to plant tissue .

HY-105832

Fenbenicillin potassium Phenbenicillin potassium; α-Phenoxybenzylpenicillin potassium	Bacterial	Infection
Fenbenicillin (Phenbenicillin) potassium is semi-synthetic penicillin with antibacterial effecst .

HY-172250

8-Hydroxyerythromycin A	Antibiotic Bacterial	Infection
8-Hydroxyerythromycin is a semi-synthetic antibiotic with an antibacterial activity .

HY-B0974R

Methicillin sodium salt (Standard) Meticillin sodium (Standard)	Penicillin-binding protein (PBP) Reference Standards Bacterial Antibiotic	Infection
Methicillin (sodium salt) (Standard) is the analytical standard of Methicillin (sodium salt). This product is intended for research and analytical applications. Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation .

HY-N15039

5-Hydroxymethyltubercidin	Antibiotic Bacterial	Infection
5-Hydroxymethyltubercidin is a semi-synthetic antibiotic made from tuberculin-5-carboxylic acid .

HY-109125A

Amcipatricin L-aspartate SPA-S-753; SPA-S-752 L-aspartate	Antibiotic Fungal	Infection
Amcipatricin diaspartate (SPA-S-753) is a semi-synthetic polyene antibiotic, with potent broad-spectrum antifungal activity .

HY-Z8447

9(E)-Erythromycin A oxime	Drug Metabolite	Infection
(9E)-Erythromycin A oxime is a metabolite of Roxithromycin (HY-B0435). Roxithromycin is a semi-synthetic macrolide antibiotic.

HY-105267

LY 121019	Fungal Antibiotic	Infection
LY 121019 is a semi-synthetic antifungal antibiotic with strong anticandida activity with MIC₅₀ value of 0.625 μg/mL .

HY-161300

Antibacterial agent 191	Bacterial Antibiotic	Infection
Antibacterial agent 191 (compound 11a) is a potent semi-synthetic antibiotic. Antibacterial agent 191 exhibits preferable metabolic stability .

HY-B0435R

Roxithromycin (Standard) RU-28965 (Standard)	Reference Standards Bacterial Antibiotic	Infection
Roxithromycin (Standard) is the analytical standard of Roxithromycin. This product is intended for research and analytical applications. Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.

HY-151224R

Thermospermine (Standard)	DNA/RNA Synthesis Reference Standards	Others
Roxithromycin (Standard) is the analytical standard of Roxithromycin. This product is intended for research and analytical applications. Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.

HY-135102

Laidlomycin propionate potassium	Biochemical Assay Reagents	Others
Laidlomycin propionate potassium is a semi-synthetic ionophore, which can be used as a feed additive for cattle to improve the rate of gain and feed conversion efficiency .

HY-137054

Ukrain NSC-631570	Drug Intermediate	Cancer
Ukrain (NSC-631570) is an anticancer agent. Ukrain is a semi-synthetic compound derived from the common weed, greater celandine (Chelidonium majus L.) .

HY-15459S1

Cabazitaxel-d9 XRP6258-d₉; RPR-116258A-d₉; taxoid XRP6258-d₉	Isotope-Labeled Compounds Microtubule/Tubulin Autophagy	Cancer
Cabazitaxel-d₉ is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-148286

Gentamicin C1a	Antibiotic Bacterial	Infection
Gentamicin C1a is the precursor of the semi-synthetic antibiotic Etimicin, and has antibacterial activity. Gentamicin C1a is the major component of the Gentamicin complex .

HY-113602

Paldimycin B Antibiotic 273 A1-beta	Antibiotic Bacterial	Infection
Paldimycin B (Antibiotic 273 A1-beta) is a powerful semi-synthetic antibiotic with antibacterial activity against S. aureus and coagulase-negative staphylococci .

HY-15459S

Cabazitaxel-d6 XRP6258-d₆; RPR-116258A-d₆; taxoid XRP6258-d₆	Microtubule/Tubulin Autophagy	Cancer
Cabazitaxel-d₆ is the deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity .

HY-13234S

Rifaximin-d6	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Rifaximin-d₆ is the deuterium labeled Rifaximin. Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity .

HY-19502

Artemisone 1 Publications Verification Artemifone; BAY 44-9585	Parasite CMV	Infection
Artemisone (Artemifone) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains, with a mean IC₅₀ of 0.83 nM . Artemisone is also a potent inhibitor of human CMV .

HY-167714

Cefazaflur	Others	Infection
Cefazaflur is a novel semi-synthetic cephalosporin derivative that exhibits significant antibacterial activity, effectively inhibiting various strains of Staphylococcus aureus, Escherichia coli, Klebsiella, and Proteus mirabilis at low concentrations.

HY-15459R

Cabazitaxel (Standard) XRP6258 (Standard); RPR-116258A (Standard); taxoid XRP6258 (Standard)	Reference Standards Microtubule/Tubulin Autophagy	Cancer
Cabazitaxel (Standard) is the analytical standard of Cabazitaxel. This product is intended for research and analytical applications. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-B0771

Cefozopran SCE-2787	Bacterial Antibiotic	Infection
Cefozopran (SCE-2787) is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms .

HY-B0643

Dirithromycin 1 Publications Verification LY237216	Bacterial Antibiotic	Infection
Dirithromycin (LY237216), a derivative of Erythromycin, is a potent and orally active semi-synthetic macrolide antibiotic. Dirithromycin is active against gram-positive bacteria, Legionella spp., Helicobacter pylori, and Chlamydia trachomatis .

HY-B0771A

Cefozopran hydrochloride SCE-2787 hydrochloride	Bacterial Antibiotic	Infection
Cefozopran (SCE-2787) hydrochloride is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran hydrochloride, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms .

HY-107211

Echinocandin B nucleus SL 7810 nucleus; A-30912 A nucleus	Fungal Drug Intermediate	Infection
Echinocandin B nucleus (A-30912 A nucleus) is the reaction product catalyzed by Echinocandin B (HY-125723) deacylase. Echinocandin B nucleus serves as an intermediate for the synthesis of semi-synthetic antifungal agents .

HY-N12823

Caprazene	Bacterial	Metabolic Disease
Caprazene is an antimycobacterial compound and precursor molecule for semi-synthetic antibacterial antibiotics, used for studies on tuberculosis and Mycobacterium avium complex infections, which can be isolated from the acid-treated caprazamycin (CPZ) A-G mixture .

HY-B0435S

Roxithromycin-d7 RU-28965-d₇	Isotope-Labeled Compounds Antibiotic Bacterial	Others
Roxithromycin-d₇ (RU-28965-d₇) is the deuterium labeled Roxithromycin (HY-B0435) . Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic .

HY-A0203A

Pentosan Polysulfate (Sodium) (W/W 43%)	HIV	Infection Inflammation/Immunology Cancer
Pentosan Polysulfate Sodium is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also is a potent and selective anti-HIV agent. Pentosan Polysulfate Sodium is used for the treatment of interstitial cystitis .

HY-138179

7-APRA	Bacterial	Infection
7-APRA is a semi-synthetic intermediate of cephalosporin antibiotics. 7-APRA has antibacterial activity and is mainly used in the synthesis of other Cefaclor (HY-B0198) and Cefprozil (HY-B0458A) .

HY-19502R

Artemisone (Standard)	Parasite CMV	Infection
Artemisone (Standard) is the analytical standard of Artemisone. This product is intended for research and analytical applications. Artemisone (Artemifone) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains, with a mean IC50 of 0.83 nM . Artemisone is also a potent inhibitor of human CMV .

HY-148286R

Gentamicin C1a (Standard)	Reference Standards Antibiotic Bacterial	Infection
Gentamicin C1a (Standard) is the analytical standard of Gentamicin C1a. This product is intended for research and analytical applications. Gentamicin C1a is the precursor of the semi-synthetic antibiotic Etimicin, and has antibacterial activity. Gentamicin C1a is the major component of the Gentamicin complex .

HY-107212

Selamectin	Parasite Chloride Channel P-glycoprotein Bacterial	Infection
Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm, *Lymphatic filariae, and nematode* infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC₅₀ of 120 nM .

HY-B1299

Cephalosporin C 1 Publications Verification	Bacterial	Infection
Cephalosporin C has weak resistance to Gram-positive and negative bacteria, is stable to penicillinase, and can be broken down by cephalosporin enzyme. Hydrolysis and removal of side chains to obtain 7-amino-cefenoic acid (7-ACA) is an important raw material for the preparation of semi-synthetic cephalosporin .

HY-B0771AR

Cefozopran hydrochloride (Standard) SCE-2787 hydrochloride (Standard)	Reference Standards Bacterial Antibiotic	Infection
Cefozopran (hydrochloride) (Standard) is the analytical standard of Cefozopran (hydrochloride). This product is intended for research and analytical applications. Cefozopran (SCE-2787) hydrochloride is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran hydrochloride, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms .

HY-B0643R

Dirithromycin (Standard) LY237216 (Standard)	Reference Standards Bacterial Antibiotic	Infection
Dirithromycin (Standard) is the analytical standard of Dirithromycin. This product is intended for research and analytical applications. Dirithromycin (LY237216), a derivative of Erythromycin, is a potent and orally active semi-synthetic macrolide antibiotic. Dirithromycin is active against gram-positive bacteria, Legionella spp., Helicobacter pylori, and Chlamydia trachomatis .

HY-B0136

Cefdinir 2 Publications Verification FK-482; CI-983	Bacterial Antibiotic	Infection
Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .

HY-P2834

Penicillin amidase, E. coli PGA	Biochemical Assay Reagents	Infection Cancer
Penicillin amidase (EC 3.5.1.11) (Penicillin acylase) is an enzyme that cleaves the acyl side chains of penicillins. Penicillin amidase can be used for the production of 6-aminopenicillanic acid. Penicillin amidase can also be used in the resolution of racemic mixtures, peptide synthesis, and synthesis of semi-synthetic β-lactam antibiotics .

HY-107212R

Selamectin (Standard)	Reference Standards Parasite Chloride Channel P-glycoprotein Bacterial	Infection
Selamectin (Standard) is the analytical standard of Selamectin. This product is intended for research and analytical applications. Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm, *Lymphatic filariae, and nematode* infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC₅₀ of 120 nM .

HY-128872

Etrinabdione EHP-101; VCE-004.8	PPAR Cannabinoid Receptor HIF/HIF Prolyl-Hydroxylase	Metabolic Disease Inflammation/Immunology
Etrinabdione (EHP-101; VCE-004.8) is an orally active, specific PPARγ and CB₂ receptor dual agonist. Etrinabdione inhibits prolyl-hydroxylases (PHDs) and activates the HIF pathway. Etrinabdione, a semi-synthetic multitarget cannabinoquinoid, has potent anti-inflammatory activity. Etrinabdione attenuates adipogenesis and prevents diet-induced obesity .

HY-B0136R

Cefdinir (Standard) FK-482 (Standard); CI-983 (Standard)	Reference Standards Bacterial Antibiotic	Infection
Cefdinir (Standard) is the analytical standard of Cefdinir. This product is intended for research and analytical applications. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .

HY-139554A

Zifanocycline TFA KBP-7072 TFA	Bacterial	Infection
Zifanocycline (KBP-7072) TFA is an orally active, semi-synthetic aminomethylcycline antibiotic that inhibits the normal function of bacterial ribosomes. Zifanocycline TFA has broad spectrum in vitro antimicrobial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline TFA is indicated for the study of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .

HY-17466

Sancycline Bonomycin; 6-Demethyl-6-deoxytetracycline	Bacterial Antibiotic	Metabolic Disease Inflammation/Immunology
Sancycline (6-Demethyl-6-deoxytetracycline) acts by reversibly binding to the 30 S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome a site similar to tetracycline (HY-A0107). Sancycline, four linearly fused six-membered rings with four stereocenters, is a rare semi-synthetic tetracycline (HY-A0107) prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin .

HY-113640

BC-7013	Bacterial	Infection
BC-7013 is a novel semi-synthetic pleuromutilin derivative. BC-7013 has excellent activity against Gram-positive pathogenic bacteria. BC-7013 exhibits potent antibacterial properties against both Staphylococcus, Streptococcus and penicillin-resistant Streptococcus pneumoniae. BC-7013 has activity against Gram-positive pathogenic bacteria, BC-7013 is useful in the research of acute bacterial skin and skin structure infection (ABSSSI) .

HY-B0136S

Cefdinir-13C,15N2 FK-482-¹³C,¹⁵N₂; CI-983-¹³C,¹⁵N₂	Isotope-Labeled Compounds Antibiotic Bacterial	Infection
Cefdinir- ¹³C, ¹⁵N₂ (FK-482- ¹³C, ¹⁵N₂) is ¹³C and ¹⁵N labeled Cefdinir. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .

HY-17466A

Sancycline hydrochloride Bonomycin hydrochloride; 6-Demethyl-6-deoxytetracycline hydrochloride	Antibiotic Bacterial	Metabolic Disease Inflammation/Immunology
Sancycline (6-Demethyl-6-deoxytetracycline) hydrochloride acts by reversibly binding to the 30 S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome a site similar to tetracycline (HY-A0107). Sancycline hydrochloride, four linearly fused six-membered rings with four stereocenters, is a rare semi-synthetic tetracycline (HY-A0107) prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin .

Cat. No.	Product Name

HY-L071

Alkaloids Library

555 compounds

Alkaloids are a large and complex group of cyclic compounds that contain N. About 2,000 different alkaloids have been isolated. Important alkaloids include morphine, strychnine, atropine, colchicine, ephedrine, quinine, and nicotine. Alkaloids are useful as diet ingredients, supplements, and pharmaceuticals, in medicine and in other applications in human life. They showed anti-inflammatory, anticancer, analgesics, local anesthetic and pain relief, neuropharmacologic, antimicrobial, antifungal, and many other activities. Alkaloids are also important compounds in organic synthesis for searching new semisynthetic and synthetic compounds with possibly better biological activity than parent compounds.

MCE designs a unique collection of 555 alkaloids that all come from natural products. MCE Alkaloids Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

Cat. No.	Product Name	Target	Research Area

HY-105267

LY 121019	Fungal Antibiotic	Infection
LY 121019 is a semi-synthetic antifungal antibiotic with strong anticandida activity with MIC₅₀ value of 0.625 μg/mL .

HY-P6372

SDZ 280-446	Peptides
SDZ 280-446 is an orally active semisynthetic cyclic peptide lactone. SDZ 280-446 can be used in anticancer research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-15459

Cabazitaxel 15+ Cited Publications XRP6258; RPR-116258A; taxoid XRP6258	Structural Classification Natural Products Classification of Application Fields Taxaceae Source classification Plants Disease Research Fields Taxus chinensis (Pilger) Rehd. Cancer	Microtubule/Tubulin Autophagy
Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-N15039

5-Hydroxymethyltubercidin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
5-Hydroxymethyltubercidin is a semi-synthetic antibiotic made from tuberculin-5-carboxylic acid .

HY-151224R

Thermospermine (Standard)	Microorganisms Source classification	DNA/RNA Synthesis Reference Standards
Roxithromycin (Standard) is the analytical standard of Roxithromycin. This product is intended for research and analytical applications. Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic.

HY-15459R

Cabazitaxel (Standard) XRP6258 (Standard); RPR-116258A (Standard); taxoid XRP6258 (Standard)	Structural Classification Natural Products Taxaceae Source classification Plants Taxus chinensis (Pilger) Rehd.	Reference Standards Microtubule/Tubulin Autophagy
Cabazitaxel (Standard) is the analytical standard of Cabazitaxel. This product is intended for research and analytical applications. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-107211

Echinocandin B nucleus SL 7810 nucleus; A-30912 A nucleus	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal Drug Intermediate
Echinocandin B nucleus (A-30912 A nucleus) is the reaction product catalyzed by Echinocandin B (HY-125723) deacylase. Echinocandin B nucleus serves as an intermediate for the synthesis of semi-synthetic antifungal agents .

HY-N12823

Caprazene	Structural Classification Microorganisms Antibiotics Source classification	Bacterial
Caprazene is an antimycobacterial compound and precursor molecule for semi-synthetic antibacterial antibiotics, used for studies on tuberculosis and Mycobacterium avium complex infections, which can be isolated from the acid-treated caprazamycin (CPZ) A-G mixture .

HY-148286R

Gentamicin C1a (Standard)	Microorganisms Source classification	Reference Standards Antibiotic Bacterial
Gentamicin C1a (Standard) is the analytical standard of Gentamicin C1a. This product is intended for research and analytical applications. Gentamicin C1a is the precursor of the semi-synthetic antibiotic Etimicin, and has antibacterial activity. Gentamicin C1a is the major component of the Gentamicin complex .

HY-N14967

Epicillin	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Epicillin is found in the strain of Semisynthetic broad-spectrum penicillin with antibacterial activities .

HY-122503

Guamecycline	Structural Classification Antibiotics Source classification Endogenous metabolite Other Antibiotics	Antibiotic Bacterial
Guamecycline is a semisynthetic tetracycline. The antibacterial spectrum and antibacterial activity are the same as Tetracycline .

HY-N8442

Drimenol (-)-Drimenol	Structural Classification Terpenoids Sesquiterpenes Source classification Valeriana officinalis Linn. Plants Valerianaceae	Others
Drimenol is a drimane-type sesquiterpene that can be isolated from Valerian plant .

HY-N10511

GM1a Ganglioside oligosaccharide	Structural Classification Natural Products Polysaccharides Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Saccharides	Others
GM1a Ganglioside oligosaccharide is a semisynthetic form of ganglioside GM1. Ganglioside GM1 is the natural receptor for cholera toxin and plays an important role not only in general growth regulation but also in the coupling of hormone-induced responses .

HY-B0529R

Azlocillin (Standard)	Microorganisms Source classification	Reference Standards Bacterial Parasite Antibiotic
Azlocillin (Standard) is the analytical standard of Azlocillin. This product is intended for research and analytical applications. Azlocillin, an antibiotic, is a semisynthetic penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection .

Cat. No.	Product Name	Chemical Structure

HY-15459S1

Cabazitaxel-d9
Cabazitaxel-d₉ is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-15459S

Cabazitaxel-d6
Cabazitaxel-d₆ is the deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity .

HY-13234S

Rifaximin-d6
Rifaximin-d₆ is the deuterium labeled Rifaximin. Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity .

HY-B0435S

Roxithromycin-d7
Roxithromycin-d₇ (RU-28965-d₇) is the deuterium labeled Roxithromycin (HY-B0435) . Roxithromycin (RU-28965) is a semi-synthetic macrolide antibiotic .

HY-W654013

Minocycline-d7

Minocycline-d₇ is deuterium labeled Minocycline. Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .

HY-17412S1

Minocycline-d6 sulfate

Minocycline-d₆ sulfate is deuterated labeled Minocycline (HY-17412A). Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .

HY-B0136S

Cefdinir-13C,15N2

Cefdinir- ¹³C, ¹⁵N₂ (FK-482- ¹³C, ¹⁵N₂) is ¹³C and ¹⁵N labeled Cefdinir. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .

HY-17412S

Minocycline-d6 hydrochloride

Minocycline-d₆ hydrochloride is deuterated labeled Minocycline hydrochloride (HY-17412). Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline hydrochloride shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline hydrochloride inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .

HY-17412AS

Minocycline-d6

Minocycline-d₆ is deuterium labeled Minocycline (HY-17412A). Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .

HY-B1588S

Carbenoxolone-d4

Carbenoxolone-d₄ is deuterium labeled Carbenoxolone. Carbenoxolone, a semi-synthetic derivative of glycyrrhetinic acid, has previously been used for the management of dyspepsia and peptic ulcer because of its anti-inflammatory properties . Carbenoxolone, a general hemichannel and gap junction inhibitor, has the therapeutic potential of carbenoxolone in the research of chronic liver disease . Carbenoxolone is a suitable candidate for the inhibition of Aβ42 aggregation and the therapeutic potential of Cbx against AD . Carbenoxolone is small molecule Pannexin1 (Panx1,is an ATP release channel) inhibitor, attenuate Panx1 channel activity through modulation of the first extracellular loop .Carbenoxolone is an 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor that converts inactive glucocorticoid into an active form. Carbenoxolone has antiviral activity against DENV infection targeting the virus itself .

HY-B0210S

Cefoperazone-d5
Cefoperazone-d₅ is deuterium labeled Cefoperazone. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .

HY-13553S1

Anidulafungin-13C6
Anidulafungin- ¹³C₆ (LY303366- ¹³C₆) is ¹³C labeled Anidulafungin. Anidulafungin is a new semisynthetic echinocandin with antifungal potency.

HY-17025S

Rifabutin-d7
Rifabutin-d₇ is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-17025S1

Rifabutin-d6
Rifabutin-d₆ (Ansamycin-d₆) is deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-W749665

Clindamycin Hydrochloride-13C,d3
Clindamycin Hydrochloride- ¹³C,d₃ is the deuterium and ¹³C-labeled Clindamycin hydrochloride (HY-B0408A). Clindamycin hydrochloride is a semisynthetic lincosamide antibiotic, which inhibits protein synthesis by acting on the 50S ribosomal.

HY-B1923S

Piperacillin-d5
Piperacillin-d₅ is deuterium labeled Piperacillin. Piperacillin is kind of semisynthetic penicillins. Piperacillin has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Piperacillin has shown greater activity against β-lactamase-producing organisms than the other penicillins .

HY-17586AS

Dalbavancin-d6
Dalbavancin-d₆ is the deuterium labeled Dalbavancin . Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively .

HY-B0011AS

Docetaxel-d5 trihydrate

Docetaxel-d₅ (trihydrate) is the deuterium labeled Docetaxel (Trihydrate). Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule?depolymerization with an IC₅₀ value of 0.2 μM . Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of?bcl-2?and?bcl-xL?gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis .

HY-W653936

Cephalexin-d5 hydrate

Cephalexin-d₅ (hydrate) is deuterium labeled Cephalexin (monohydrate). Cephalexin (Cefalexin) monohydrate is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) monohydrate targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al .

Cat. No.	Product Name		Classification

HY-B2091

Azidocillin		Azide
Azidocillin, a semi-synthetic Penicillin, is an orally active β-lactam antibiotic. Azidocillin bears an azide functionality and retains on-target activity within bacteria. Azidocillin can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases . Azidocillin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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