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Results for "

ionization

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (3) ATM/ATR (1) Bacterial (5) Biochemical Assay Reagents (13) Caspase (2) CD28 (2) CDK (1) Checkpoint Kinase (Chk) (1) COX (2) Cytochrome P450 (1) DNA-PK (2) DNA/RNA Synthesis (2) Drug Derivative (1) Drug Intermediate (3) Endogenous Metabolite (3) Fluorescent Dye (1) Glutathione Peroxidase (1) IFNAR (2) Interleukin Related (2) Isotope-Labeled Compounds (2) Lipase (2) Liposome (129) Lipoxygenase (2) MDM-2/p53 (1) Mitochondrial Metabolism (1) Mitophagy (1) Monocarboxylate Transporter (1) NF-κB (1) Notch (2) Parasite (1) PARP (3) Phosphatase (1) Phosphodiesterase (PDE) (1) Pyroptosis (2) Reactive Oxygen Species (ROS) (3) Reference Standards (1) SARS-CoV (1) Small Interfering RNA (siRNA) (1) STAT (1) Toll-like Receptor (TLR) (2)
By Research Areas:	Cancer (47) Cardiovascular Disease (2) Infection (13) Inflammation/Immunology (24) Metabolic Disease (4) Neurological Disease (4)
Click Chemistry:	Azide (1)
Oligonucleotides:	Cationic Lipids (84) Phospholipids (1)

173

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148648

Lipid 29	Liposome	Others
Lipid 29 is an ionizable amino lipid. Lipid 29 can be used to form lipid nanoparticles .

HY-158796

L202	Liposome	Others
L202 is an ionizable cationic lipid (pKa=6.04) that can be used for the study of mRNA and lipid nanoparticles .

HY-160439

Ionizable lipid-2	Liposome	Others
Ionizable lipid-2 (Compound 1) is an ionizable lipid that can be used for the preparation of lipid nanoparticles and vaccine research .

HY-160553

9322-O16B	Liposome	Others
9322-O16B, an ionizable cationic lipid, is used for LNP generation .

HY-159858

Lipid 16	Liposome	Cancer
Lipid 16 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads. Lipid 16 as a potent cell type-specific ionizable lipid for the CD11bhi macrophage population without an additional targeting moiety .

HY-W590548

ATX-001	Liposome	Others
ATX-001 is an ionizable cationic lipid. ATX-001 can be used in the formation of lipid nanoparticles (LNPs) for the delivery mRNA .

HY-151507

306Oi10	Liposome	Others
306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .

HY-W598178

93-O17O	Liposome	Others
93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .

HY-159708

Ionizable lipid Az1	Liposome	Others
Ionizable lipid Az1is an ionizable lipid which can react with a variety of terminal alkynes under the CuAAC standard condition .

HY-142995

DODAP hydrochloride	Liposome	Others
DODAP (hydrochloride) is an ionizable lipid. DODAP (hydrochloride) has the potential for the research of gene delivery .

HY-167004A

IAJD249	Liposome	Others
IAJD249 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. IAJD249 can be used in the preparation of liposomes .

HY-167004

IAJD93	Liposome	Others
IAJD93 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. IAJD93 can be used in the preparation of liposomes .

HY-167003

L16	Liposome	Others
L16 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. L16 can be used in the preparation of liposomes .

HY-172344

DB-lipidoid 11-10-8	Biochemical Assay Reagents	Others
DB-lipidoid 11-10-8 is an ionizable cationic lipid (pK_a = 6.22). DB-lipidoid 11-10-8 can be used in lipid nanoparticle (LNP) studies for in vivo delivery of mRNA .

HY-145793

FTT5 1 Publications Verification	Liposome	Cardiovascular Disease
FTT5 is an ionizable lipid that can be used to prepare lipid nanoparticles for efficient delivery of long-chain mRNA in vivo .

HY-167002

RM 137-15	Liposome	Others
RM 137-15 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. RM 137-15 can be used in the preparation of liposomes .

HY-167011

Al-28	Liposome	Others
Al-28 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. Al-28 can be used in the preparation of liposomes .

HY-167015

1O14	Liposome	Others
1O14 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. 1O14 can be used in the preparation of liposomes .

HY-159717

Lipid 331	Liposome	Others
Lipid 331 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid 331 is a carrier for both siRNA and mRNA .

HY-159865

CL15F6	Liposome	Others
CL15F6 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .

HY-159726

C10-200	Liposome	Others
C10-200 is an ionizable cationic lipid that can be used to generate lipid nanoparticles (LNPs). C10-200 is used in the study of mRNA delivery .

HY-150118

Lipid 8	Liposome	Others
Lipid 8 is an ionizable amino lipid that can be used to synthesize lipid nanoparticles (LNPs). Lipid 8 is applicable to research in drug delivery .

HY-159709

VL-422	Liposome	Others
VL-422 is an ionizable cationic lipid that can be used for lipid nanoparticle (LNP) and drug delivery research .

HY-112418

CDK4/6-IN-18	CDK	Cancer
CDK4/6-IN-18 (Example 2BrIC) is a selective CDK4/6 inhibitor. CDK4/6-IN-18 inhibits ionizing radiation (IR)-induced DNA damage in cells .

HY-159716

Lipid 50	Liposome	Others
Lipid 50 (compound 50) is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid 50 is a carrier for both siRNA and mRNA .

HY-159715

Lipid DIM1	Liposome	Others
Lipid DIM1 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid DIM1 is a carrier for both siRNA and mRNA .

HY-159714

Lipid HTO12	Liposome	Others
Lipid HTO12 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid HTO12 is a carrier for both siRNA and mRNA .

HY-159710

TNT-b10	Liposome	Others
TNT-b10 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). TNT-b10 is a carrier for both siRNA and mRNA .

HY-167012

306Oi9-cis2	Liposome	Others
306Oi9-cis2 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. 306Oi9-cis2 can be used in the preparation of liposomes .

HY-W590681

113-O12B	Liposome	Others
113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA .

HY-W590679

113-O16B	Liposome	Others
113-O16B is a disulfide bond-containing ionizable cationic lipidoid. 113-O16B has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA .

HY-107641

α-Cyano-4-hydroxycinnamic acid 4 Publications Verification α-Cyano-4-hydroxycinnamate	Monocarboxylate Transporter	Metabolic Disease
α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a K_i of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications .

HY-171114

DMT7	Liposome	Others
DMT7 is an ionizable cationic lipid (pKa = 6.5) that can be used to generate lipid nanoparticles (LNPs) for delivery of mRNA and anticancer drugs in the body .

HY-D0202

Arsenazo III	Fluorescent Dye	Others
Arsenazo III is a dye useful for detection of micromolar concentrations of ionized Ca ²⁺. Arsenazo III can be used for determination of thorium, zirconium, uranium and rare earth elements .

HY-161622

K1586	Checkpoint Kinase (Chk)	Cancer
K1586 is an amidine derivative that efficiently targets Chk1. K1586 enhances the degradation of Chk1 that sensitizes colorectal cancer cells to ionizing radiation. K1586 shows anticancer effects .

HY-W141932

N-Stearoylglycine Stearoylglycine; N-Octadecanoylglycine	Endogenous Metabolite	Others
N-stearoylglycine is a lipid and has a small ionizable polar headgroup whose charge is pH dependent and whose amide moiety can form H-bonded network between adjacent molecules in ordered films .

HY-148842

C14-4	Liposome	Others
C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity .

HY-172336

4-O10b1	Liposome	Inflammation/Immunology
4-O10b1 is an ionizable cationic lipid. 4-O10b1 can be used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo .

HY-116621

NU-7163	DNA-PK	Cancer
NU-7163 is an ATP-competitive DNA-PK inhibitor (IC₅₀=0.19 μM; K_i=24 nM). NU-7163 enhances the cytotoxicity of ionizing radiation against the HeLa human tumor cell line in vitro .

HY-168776

(S)-C12-200	Biochemical Assay Reagents	Others
(S)-C12-200 is the (S)-isomer of C12-200 (HY-145405), an ionizable cationic lipid and helper lipid. (S)-C12-200 can be utilized in the formation of lipid nanoparticles and mRNA delivery .

HY-159700

AA3-DLin	Liposome	Infection
AA3-DLin is an ionizable cationic lipid with a pK_a value of 5.8. AA3-DLin is used to delivery mRNA combined with lipid nanoparticles (LNPs). AA3-DLin LNP COVID-19 vaccines encapsulating SARS CoV-2 spike mRNAs successfully induces strong immunogenicity in a BALB/c mouse model .

HY-160552

244cis	Liposome	Others
244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels .

HY-172535

Lipid OA2 dihydrochloride	Lipase	Inflammation/Immunology Cancer
Lipid OA2 dihydrochloride is an ionizable cationic lipid that can be used to prepare single-component lipid nanoparticles for siRNA delivery. Lipid OA2 dihydrochloride can effectively deliver SOCS1-siRNA to dendritic cells, silence the SOCS1 gene, and enhance their antigen-presenting ability and pro-inflammatory factor secretion capacity .

HY-172334

2N12B	Liposome	Metabolic Disease
2N12B is a bioreducible ionizable lipid containing disulfide bonds. 2N12B can be used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. Lipid nanoparticles containing 2N12B can deliver siRNA to inhibit retinal neovascularization .

HY-145405

C12-200 10+ Cited Publications	Liposome	Others
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .

HY-N0232

Psoralidin 4 Publications Verification	COX Lipoxygenase Notch Reactive Oxygen Species (ROS) Bacterial	Cancer
Psoralidin is a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation.Anti-cancer, anti-bacterial, and anti-inflammatory properties . Psoralidin significantly downregulates NOTCH1 signaling. Psoralidin also greatly induces ROS generation .

HY-N0232R

Psoralidin (Standard)	Reference Standards COX Lipoxygenase Notch Reactive Oxygen Species (ROS) Bacterial	Cancer
Psoralidin (Standard) is the analytical standard of Psoralidin. This product is intended for research and analytical applications. Psoralidin is a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation.Anti-cancer, anti-bacterial, and anti-inflammatory properties . Psoralidin significantly downregulates NOTCH1 signaling. Psoralidin also greatly induces ROS generation .

HY-172526

4A3-SCC-10	Liposome	Cancer
4A3-SCC-10 is a biodegradable ionizable lipid containing disulfide bonds. 4A3-SCC-10 can be used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. 4A3-SCC-10 can be used for broad applications such as gene editing, vaccine, and cancer detection .

HY-159861

Ionizable Lipid 4	Liposome	Others
Ionizable Lipid 4 is an ionizable cationic lipid and a rearrangement product of the cationic lipid CA-lipid 5 induced by hydrogen peroxide .

HY-156630

Ionizable lipid-1 1 Publications Verification	Liposome	Others
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .

Cat. No.	Product Name

HY-L178

Radioprotector Library

2,265 compounds

Radiation sickness is a general term for various types and degrees of damage (or disease) occurring in the human body after exposure to ionizing radiation. Although small amounts of ionizing radiation can also cause the body to produce free radicals and ROS, causing oxidative stress, resulting in DNA damage and chromosomal aberration. Radioprotector are compounds with radiation protection that can be used to prevent/protect non-tumor cells from the harmful effects of radiation. Radioprotective compounds can prevent the damage of radioactive substances to the human body and reduce the clinical symptoms of various radioactive diseases. In addition, radioprotectors can protect normal cells from damage during radiation therapy. The ideal anti-radiation drug should not affect the sensitivity of tumor cells to radiation therapy while protecting normal cells.

MCE designs a unique collection of 2,265 radioprotectors. Radioprotector Library is an effective tool for acute Radiation Syndrome, drug combination research with radiation drugs.

Cat. No.	Product Name	Type

HY-D0202

Arsenazo III	Dyes
Arsenazo III is a dye useful for detection of micromolar concentrations of ionized Ca ²⁺. Arsenazo III can be used for determination of thorium, zirconium, uranium and rare earth elements .

HY-112251GL

D-Lin-MC3-DMA (GMP Like)	Fluorescent Dye
D-Lin-MC3-DMA (GMP Like) is the GMP Like class D-Lin-MC3-DMA (HY-112251). D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.

Cat. No.	Product Name	Type

HY-148648

Lipid 29	Drug Delivery
Lipid 29 is an ionizable amino lipid. Lipid 29 can be used to form lipid nanoparticles .

HY-151507

306Oi10

Drug Delivery

306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .

HY-167004A

IAJD249	Drug Delivery
IAJD249 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. IAJD249 can be used in the preparation of liposomes .

HY-167004

IAJD93	Drug Delivery
IAJD93 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. IAJD93 can be used in the preparation of liposomes .

HY-167003

L16	Drug Delivery
L16 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. L16 can be used in the preparation of liposomes .

HY-145793

FTT5 1 Publications Verification	Drug Delivery
FTT5 is an ionizable lipid that can be used to prepare lipid nanoparticles for efficient delivery of long-chain mRNA in vivo .

HY-167011

Al-28	Drug Delivery
Al-28 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. Al-28 can be used in the preparation of liposomes .

HY-167015

1O14	Drug Delivery
1O14 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. 1O14 can be used in the preparation of liposomes .

HY-142995

DODAP hydrochloride	Drug Delivery
DODAP (hydrochloride) is an ionizable lipid. DODAP (hydrochloride) has the potential for the research of gene delivery .

HY-167002

RM 137-15	Drug Delivery
RM 137-15 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. RM 137-15 can be used in the preparation of liposomes .

HY-150118

Lipid 8	Drug Delivery
Lipid 8 is an ionizable amino lipid that can be used to synthesize lipid nanoparticles (LNPs). Lipid 8 is applicable to research in drug delivery .

HY-167012

306Oi9-cis2	Drug Delivery
306Oi9-cis2 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. 306Oi9-cis2 can be used in the preparation of liposomes .

HY-148842

C14-4	Drug Delivery
C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity .

HY-145405

C12-200 10+ Cited Publications	Drug Delivery
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .

HY-156630

Ionizable lipid-1 1 Publications Verification	Drug Delivery
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .

HY-156630A

Ionizable lipid-1 hydrochloride	Drug Delivery
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .

HY-145739

ATX-0114	Drug Delivery
ATX-0114 is an ionizable cationic lipid .

HY-145796

503O13	Drug Delivery
503O13 is a degradable ionizable lipid for siRNA delivery.

HY-147332

TCL053	Drug Delivery
TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .

HY-150115

Lipid 10 1 Publications Verification	Drug Delivery
Lipid 10 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

HY-150117

Lipid 6	Drug Delivery
Lipid 6 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

HY-153378

Lipid 15	Drug Delivery
Lipid 15 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

HY-150116

Lipid 1	Drug Delivery
Lipid 1 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

HY-134782

OF-Deg-Lin	Drug Delivery
OF-Deg-Lin is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

HY-153373

4A3-Cit	Drug Delivery
4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).

HY-156857

PPZ-A10	Drug Delivery
PPZ-A10 is a ionizable lipid that delivered mRNA preferentially to liver and spleen immune cells.

HY-145797

L343	Drug Delivery
L343 is an ionizable cationic lipidoid and can be used to synthetic liposomes for systemic delivery of RNAi therapeutics.

HY-112251

D-Lin-MC3-DMA Maximum Cited Publications 96 Publications Verification	Drug Delivery
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.

HY-153372

93-O17S	Drug Delivery
93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs).

HY-112757

DLinDMA 1 Publications Verification	Drug Delivery
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery .

HY-W590532

306-O12B	Drug Delivery
306-O12B is an ionizable cationic lipid used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA .

HY-112772A

98N12-5	Drug Delivery
98N12-5 is a novel multi-tail ionizable lipids that has been used for efficient in vivo siRNA-delivery to the liver.

HY-149156

Lipid C24	Drug Delivery
Lipid C24 is a cationic ionizable lipid that can be used for synthesizing lipid nanoparticles. Lipid C24 can be used in the study of drug delivery .

HY-139298

L319 1 Publications Verification Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate	Drug Delivery
L319 is an ionizable cationic lipidoid and can be used for synthetic liposomes, from the patent WO-2011153493-A2, compound 1 .

HY-151511

A12-Iso5-2DC18	Drug Delivery
A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .

HY-153186

LNP Lipid-3	Drug Delivery
LNP Lipid-3 is an ionizable lipid that can be used to synthesize lipid nanoparticles. LNP Lipid-3 can be applied in the research of drug delivery .

HY-153376

LNP Lipid-6	Drug Delivery
LNP Lipid-6 (Compound Lipid 5) is an ionizable lipid (amino lipid). LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) .

HY-46759A

Genevant CL1 monohydrochloride	Drug Delivery
Genevant CL1 monohydrochloride is an ionizable lipid (lipid 10, pK_a=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery .

HY-153375

LNP Lipid-5	Drug Delivery
LNP Lipid-5 (Compound Lipid 2) is an ionizable lipid (amino lipid). LNP Lipid-5 can be used to prepare lipid nanoparticles (LNP) .

HY-149167

ATX-0126 ATX 100	Drug Delivery
ATX-0126 (ATX 100) is an ionizable lipid based on thiocarbamate. ATX-0126 can be involved in the formation of lipid nanoparticles and is used in research such as nucleic acid delivery .

HY-148049

TT3	Drug Delivery
TT3 is an ionizable lipid-like material and a lipid nanoparticle (LLNs)-based mRNA delivery vector. TT3 exhibits liver and spleen specificity and excellent delivery efficiency .

HY-15620

Methylproamine 1 Publications Verification	Gene Sequencing and Synthesis
Methylproamine is a DNA-binding radioprotector, acts by repair of transient radiation-induced oxidative species on DNA. Methylproamine also protects against ionizing radiation by preventing DNA double-strand breaks .

HY-46759

Genevant CL1	Drug Delivery
Genevant CL1 (Lipid 10) is an ionizable lipid (pKa=6.3). Genevant CL1 can be used for mRNA lipid nanoparticle (LNP) vaccine delivery .

HY-142654

ATX-002	Drug Delivery
ATX-002 is an ionizable cationic lipid for RNA drug delivery. The calculated pKa (c-pKa) and measured pKa values for ATX-002 are 8.68 and 6.03, respectively .

HY-153737

113-N16B	Drug Delivery
113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.

HY-148855

OF-C4-Deg-Lin	Drug Delivery
OF-C4-Deg-Lin is an ionizable lipid with varied linker lengths. OF-C4-Deg-Lin can be used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA .

HY-134781

CKK-E12 1 Publications Verification	Drug Delivery
CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,

HY-157252

CL4F8-6	Drug Delivery
CL4F8-6 is an ionizable cationic lipid with a pK_a of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics .

HY-112251GL

D-Lin-MC3-DMA (GMP Like)	Biochemical Assay Reagents
D-Lin-MC3-DMA (GMP Like) is the GMP Like class D-Lin-MC3-DMA (HY-112251). D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.

HY-151512

A12-Iso5-4DC19	Drug Delivery
A12-Iso5-4DC19 is an ionizable cationic lipid. A12-Iso5-4DC19 can facilitate mRNA delivery and be used for the research of RNA vaccines .

Cat. No.	Product Name	Target	Research Area

HY-W141932

N-Stearoylglycine Stearoylglycine; N-Octadecanoylglycine	Endogenous Metabolite	Others
N-stearoylglycine is a lipid and has a small ionizable polar headgroup whose charge is pH dependent and whose amide moiety can form H-bonded network between adjacent molecules in ordered films .

HY-P1698

Reltecimod AB-103	Bacterial CD28	Infection Inflammation/Immunology Cancer
Reltecimod (AB-103) is a T-cell-specific surface glycoprotein CD28 (TP44) antagonist. Reltecimod has beneficial effects against different bacterial infections, their exotoxins and endotoxins, and ionizing radiation. Reltecimod modulates the inflammatory response by targeting and attenuating the critical CD28/B7-2 co-stimulatory pathway, without inhibiting it. Reltecimod can be used to research necrotizing soft-tissue infections (NSTIs) .

HY-P1698B

Reltecimod TFA AB-103 TFA	Bacterial CD28	Infection Inflammation/Immunology Cancer
Reltecimod (AB-103) TFA is a T-cell-specific surface glycoprotein CD28 (TP44) antagonist. Reltecimod TFA has beneficial effects against different bacterial infections, their exotoxins and endotoxins, and ionizing radiation. Reltecimod TFA modulates the inflammatory response by targeting and attenuating the critical CD28/B7-2 co-stimulatory pathway, without inhibiting it. Reltecimod TFA can be used to research necrotizing soft-tissue infections (NSTIs) .

HY-P1733

BMf-BH3 BMF-Y	Apoptosis	Cancer
BMf-BH3 (BMF-Y) belongs to the Bcl-2 apoptosis mediator family. BH3-only protein, Bmf is a key molecule for histone deacetylase (HDAC) inhibitors mediated enhancing effect on ionizing radiation-induced cell death .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0232

Psoralidin 4 Publications Verification	Structural Classification Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields Cancer	COX Lipoxygenase Notch Reactive Oxygen Species (ROS) Bacterial
Psoralidin is a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation.Anti-cancer, anti-bacterial, and anti-inflammatory properties . Psoralidin significantly downregulates NOTCH1 signaling. Psoralidin also greatly induces ROS generation .

HY-113485

Melanin 1 Publications Verification	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation.

HY-Y0030

3-Hydroxypicolinic acid 3-hydroxypyridine-2-carboxylic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Endogenous metabolite Disease Research Fields	Biochemical Assay Reagents Drug Intermediate
3-Hydroxypicolinic acid is a matrix. 3-Hydroxypicolinic acid coordinates with metal ions such as copper to form complexes with cytotoxic and antimycobacterial activity. 3-Hydroxypicolinic acid is used for the analysis of oligodeoxynucleotides in matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). 3-Hydroxypicolinic acid is useful for nucleic acid analysis and anti-tuberculosis compound development .

HY-N0232R

Psoralidin (Standard)	Structural Classification Leguminosae Source classification Phenols Polyphenols Psoralea corylifolia L. Plants	Reference Standards COX Lipoxygenase Notch Reactive Oxygen Species (ROS) Bacterial
Psoralidin (Standard) is the analytical standard of Psoralidin. This product is intended for research and analytical applications. Psoralidin is a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation.Anti-cancer, anti-bacterial, and anti-inflammatory properties . Psoralidin significantly downregulates NOTCH1 signaling. Psoralidin also greatly induces ROS generation .

HY-107273

Delavinone Sinpeinine A	Alkaloids Piperidine Alkaloids Fritillaria pallidiflora Liliaceae Classification of Application Fields Source classification Plants Disease Research Fields Inflammation/Immunology	Others
Delavinone (Sinpeinine A) is an alkaloid . Delavinone is suitable for electrospray ionization (ESI) positive electrode detection .

HY-N8639

Chrysin 8-C-β-D-glucoside	Structural Classification Flavonoids Flavones Source classification Rosaceae Plants Prunus avium	Others
Chrysin 8-C-β-D-glucoside is a natural compound isolated from the herbs of Psidium guajava .

Cat. No.	Product Name	Chemical Structure

HY-112251S

D-Lin-MC3-DMA-13C3
D-Lin-MC3-DMA- ¹³C₃ is the ¹³C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle .

Cat. No.	Product Name		Classification