1. Metabolic Enzyme/Protease
  2. Liposome
  3. 4A3-Cit

4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).

For research use only. We do not sell to patients.

4A3-Cit

4A3-Cit Chemical Structure

CAS No. : 2768211-13-6

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Based on 1 publication(s) in Google Scholar

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Description

4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).

Molecular Weight

1571.33

Formula

C83H147N3O16S4

CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

O=C(CCN(CCCN(CCCN(CCC(OCCOC(C(CSCCC(CC/C=C(C)/C)C)C)=O)=O)CCC(OCCOC(C(CSCCC(CC/C=C(C)/C)C)C)=O)=O)C)CCC(OCCOC(C(CSCCC(CC/C=C(C)/C)C)C)=O)=O)OCCOC(C(CSCCC(CC/C=C(C)\C)C)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (63.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6364 mL 3.1820 mL 6.3640 mL
5 mM 0.1273 mL 0.6364 mL 1.2728 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6364 mL 3.1820 mL 6.3640 mL 15.9101 mL
5 mM 0.1273 mL 0.6364 mL 1.2728 mL 3.1820 mL
10 mM 0.0636 mL 0.3182 mL 0.6364 mL 1.5910 mL
15 mM 0.0424 mL 0.2121 mL 0.4243 mL 1.0607 mL
20 mM 0.0318 mL 0.1591 mL 0.3182 mL 0.7955 mL
25 mM 0.0255 mL 0.1273 mL 0.2546 mL 0.6364 mL
30 mM 0.0212 mL 0.1061 mL 0.2121 mL 0.5303 mL
40 mM 0.0159 mL 0.0796 mL 0.1591 mL 0.3978 mL
50 mM 0.0127 mL 0.0636 mL 0.1273 mL 0.3182 mL
60 mM 0.0106 mL 0.0530 mL 0.1061 mL 0.2652 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
4A3-Cit
Cat. No.:
HY-153373
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