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Results for "

broad antibacterial spectrum

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (5) Antibiotic (197) Antifolate (2) Apoptosis (9) Aurora Kinase (6) Autophagy (3) Bacterial (264) Beclin1 (3) Beta-lactamase (18) Biochemical Assay Reagents (2) Dengue Virus (1) DNA/RNA Synthesis (9) Drug Metabolite (1) Endogenous Metabolite (2) ERK (1) FAK (1) Farnesyl Transferase (1) Fluorescent Dye (2) Fungal (20) GSK-3 (6) HBV (3) HIF/HIF Prolyl-Hydroxylase (3) Influenza Virus (2) Interleukin Related (3) Isotope-Labeled Compounds (21) JNK (3) Mas-related G-protein-coupled Receptor (MRGPR) (2) MEK (1) MMP (12) Monoamine Oxidase (2) mTOR (2) NF-κB (2) Parasite (21) Penicillin-binding protein (PBP) (27) Phospholipase (1) PPAR (2) Prostaglandin Receptor (2) PTEN (2) Raf (1) Ras (1) Reference Standards (8) STAT (1) TNF Receptor (3) Topoisomerase (14) VEGFR (3)
By Research Areas:	Cancer (55) Cardiovascular Disease (3) Endocrinology (3) Infection (259) Inflammation/Immunology (40) Neurological Disease (3)

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Aurora Kinase (6)

Autophagy (3)

Bacterial (264)

Beclin1 (3)

Beta-lactamase (18)

Biochemical Assay Reagents (2)

Dengue Virus (1)

DNA/RNA Synthesis (9)

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Endogenous Metabolite (2)

ERK (1)

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Farnesyl Transferase (1)

Fluorescent Dye (2)

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Isotope-Labeled Compounds (21)

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MEK (1)

MMP (12)

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mTOR (2)

NF-κB (2)

Parasite (21)

Penicillin-binding protein (PBP) (27)

Phospholipase (1)

PPAR (2)

Prostaglandin Receptor (2)

PTEN (2)

Raf (1)

Ras (1)

Reference Standards (8)

STAT (1)

TNF Receptor (3)

Topoisomerase (14)

VEGFR (3)

By Research Areas:

Cancer (55)

Cardiovascular Disease (3)

Endocrinology (3)

Infection (259)

Inflammation/Immunology (40)

Neurological Disease (3)

274

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N3139

Ombuin	Bacterial	Infection
Ombuin, isolated from Zanthoxylum armatum, displays broad spectrum *antibacterial* effect with MIC ranges from 125 to 500 μg/mL .

HY-14865

Omadacycline 20+ Cited Publications PTK 0796; Amadacycline	Bacterial Antibiotic	Infection
Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline *antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial* protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .

HY-14865B

Omadacycline tosylate 20+ Cited Publications PTK 0796 tosylate; Amadacycline tosylate	Bacterial Antibiotic	Infection
Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline *antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial* protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .

HY-14865C

Omadacycline hydrochloride 20+ Cited Publications PTK0796 hydrochloride; Amadacycline hydrochloride	Bacterial Antibiotic	Infection
Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline *antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial* protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .

HY-14865A

Omadacycline mesylate PTK 0796 mesylate; Amadacycline mesylate	Bacterial Antibiotic	Infection
Omadacycline (PTK 0796) mesylate, a first-in-class orally active aminomethylcycline *antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline mesylate acts through the inhibition of bacterial* protein synthesis by binding to the 30S ribosomal subunit. Omadacycline mesylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline mesylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .

HY-14865R

Omadacycline (Standard)	Bacterial Antibiotic	Infection
Omadacycline (Standard) is the analytical standard of Omadacycline. This product is intended for research and analytical applications. Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline *antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial* protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .

HY-14865CR

Omadacycline hydrochloride (Standard) PTK0796 hydrochloride (Standard); Amadacycline hydrochloride (Standard)	Bacterial Antibiotic	Infection
Omadacycline (hydrochloride) (Standard) is the analytical standard of Omadacycline (hydrochloride). This product is intended for research and analytical applications. Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections[1][2][3][4].

HY-14865BR

Omadacycline (tosylate) (Standard)	Bacterial Antibiotic	Infection
Omadacycline (tosylate) (Standard) is the analytical standard of Omadacycline (tosylate). This product is intended for research and analytical applications. Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline *antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial* protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .

HY-16980

Eravacycline TP-434	Beta-lactamase Bacterial Antibiotic	Infection
Eravacycline is a potent and broad-spectrum *antibacterial* agent.

HY-127075

Alahopcin	Antibiotic Bacterial	Infection
Alahopcin is a dipeptide antibiotic with a broad antibacterial spectrum .

HY-16980A

Eravacycline dihydrochloride 25+ Cited Publications TP-434 dihydrochloride; TP-434-046	Beta-lactamase Bacterial	Infection
Eravacycline dihydrochloride (TP-434 dihydrochloride) is a potent and broad-spectrum *antibacterial* agent.

HY-B0210

Cefoperazone 4 Publications Verification	Bacterial Antibiotic	Infection
Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .

HY-105113

Cefluprenam	Antibiotic Bacterial	Infection
Cefluprenam is a β-lactam antibiotic with broad-spectrum *antibacterial* activity .

HY-B0210C

Cefoperazone dihydrate	Bacterial Antibiotic	Infection Inflammation/Immunology
Cefoperazone dihydrate, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .

HY-N14967

Epicillin	Bacterial	Infection
Epicillin is found in the strain of Semisynthetic broad-spectrum penicillin with antibacterial activities .

HY-169811

CPW-86-363	Antibiotic Bacterial	Infection
CPW-86-363 is a novel broad-spectrum cephalosporin with antibacterial activity .

HY-N14308

Aspiculamycin	Antibiotic Bacterial	Infection
Aspiculamycin, a cytosine nucleoside, is an antibiotic. Aspiculamycin has a broad spectrum of antibacterial activity .

HY-119280

Sch 29482	Antibiotic Bacterial	Infection
Sch 29482 is an orally active penem antibiotic with broad-spectrum antibacterial activity .

HY-116519

LY173013	Bacterial	Infection
LY173013 is an *antibacterial* agent with a broad spectrum antibacterial activity. LY173013 binds to PBP 3 of E.coli and can be utilized in antibacterial research .

HY-N14168

Ashimycin A	Bacterial	Infection
Ashimycin A is a Streptomycin (HY-B1906) analogue with a broad-spectrum antibacterial activity .

HY-106339

Lymecycline Mucomycin	Bacterial	Infection Inflammation/Immunology
Lymecycline is a tetracycline derivative, with broad-spectrum *antibacterial* activity and also has anti-inflammatory property.

HY-N14187

Aspergillic acid	Antibiotic Bacterial	Infection
Aspergillic acid is an antibiotic found in Aspergillus flavus. Aspergillic acid has a broad spectrum of antibacterial activity .

HY-B0210A

Cefoperazone sodium salt 4 Publications Verification CP 52640-2	Bacterial Antibiotic	Infection
Cefoperazone sodium salt (CP 52640-2), a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .

HY-13573

Biapenem 4 Publications Verification CLI 86815; L 627; LJC 10627	Beta-lactamase Bacterial Antibiotic	Infection
Biapenem (CLI 86815; L 627; LJC 10627) a parenteral carbapenem antibacterial agent with a broad spectrum.

HY-156005

Antibacterial agent 153	Bacterial	Others
Antibacterial agent 153 is a broad-spectrum antibacterial agent. Antibacterial agent 153 kills *bacteria* by acting on the bacterial cell membrane. Antibacterial agent 153 can be used for bacterial infections research .

HY-N7115

Sultamicillin	Bacterial Antibiotic	Infection
Sultamicillin is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .

HY-N7111

Sultamicillin tosylate Sultamicillin (tosilate)	Bacterial Antibiotic	Infection
Sultamicillin tosylate is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .

HY-B2072A

Cephaloridine hydrate	Antibiotic Bacterial	Infection
Cephaloridine hydrate is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity .

HY-N14170

Ashimycin B	Bacterial	Infection
Ashimycin B is a Streptomycin (HY-B1906) analogue with a broad-spectrum antibacterial activity .

HY-132282

Thiamphenicol glycinate hydrochloride	Bacterial	Infection
Thiamphenicol glycinate hydrochloride is a broad-spectrum antibacterial agent that can be used for respiratory tract infections research .

HY-B2072

Cephaloridine	Antibiotic Bacterial	Infection
Cephaloridine is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity .

HY-106959

Flurithromycin (8S)-8-Fluoroerythromycin A; P-0501A	Antibiotic Bacterial	Infection
Flurithromycin ((8S)-8-Fluoroerythromycin A) is an orally active broad spectrum antibiotic. Flurithromycin can be used in the research of bacterial infections .

HY-B1366A

Meclocycline	Antibiotic Bacterial	Infection
Meclocycline is a tetracycline antibiotic with broad-spectrum antibacterial activities, preventing skin bacterial infections such as acne vulgarisis .

HY-W588257

(+)-Thienamycin	Bacterial Beta-lactamase	Infection Inflammation/Immunology
(+)-Thienamycin is a potent broad-spectrum antibacterial and β-lactamase inhibitor that can be from Streptomyces cattleya .

HY-B1414

Chloroxylenol 1 Publications Verification p-Chloro-m-xylenol; PCMX	Bacterial Influenza Virus Parasite	Infection
Chloroxylenol is a broad-spectrum antibacterial agent that can be used to control bacteria, algae, fungi and viruses .

HY-B0798

Cefpiramide sodium SM-1652; Wy-44635	Bacterial Antibiotic	Infection
Cefpiramide sodium (SM-1652; Wy-44635) is a new Pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.

HY-B1366

Meclocycline Sulfosalicylate Salt	Antibiotic Bacterial	Infection
Meclocycline Sulfosalicylate Salt is a tetracycline antibiotic with broad-spectrum antibacterial activities, preventing skin bacterial infections such as acne vulgaris .

HY-N14192

Maltophilin	Antibiotic Fungal	Infection
Maltophilin is a broad-spectrum antifungal antibiotic that has no antibacterial effect against Gram-positive and Gram-negative bacteria .

HY-135393S

Sulfadimethoxypyrimidine-d4	Isotope-Labeled Compounds Bacterial	Infection
Sulfadimethoxypyrimidine-d₄ is a deuterium labeled Sulfadimethoxypyrimidine. Sulfadimethoxypyrimidine is a sulfonamide antibiotic with a broad-spectrum antibacterial effect .

HY-N7125

Cinnamyl acetate	Bacterial	Others
Cinnamyl acetate has a wide application in the flavor and fragrance industry . Cinnamyl acetate is a new broad spectrum antibacterial agent .

HY-B0210S

Cefoperazone-d5	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Cefoperazone-d₅ is deuterium labeled Cefoperazone. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .

HY-B1374

Florfenicol 4 Publications Verification (-)-Florfenicol; SCH-25298	Antibiotic Bacterial	Infection Inflammation/Immunology
Florfenicol ((-)-Florfenicol) is an orally active broad-spectrum antibacterial antibiotic with anti-inflammatory, pro apoptotic, and immunomodulatory functions ^[6][7].

HY-14762

Besifloxacin	Antibiotic Bacterial	Infection
Besifloxacin is a fluoroquinolone antimicrobial agent. Besifloxacin can inhibit cytokine production by monocytes. Besifloxacin has broad-spectrum antibacterial activity .

HY-123451

ACH-702	Bacterial	Infection
ACH-702 is a potent anti-tubercular agent. ACH-702 also shows broad-spectrum antibacterial activity .

HY-16487

Temafloxacin TMFX; TA-167 free acid; A-62254 free acid	Bacterial Antibiotic	Infection
Temafloxacin (TMFX) is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin is well tolerated in lower respiratory and genitourinary tract infections .

HY-N14485

Nebramycin Ⅳ	Antibiotic Bacterial	Infection
Nebramycin IV is an aminoglycoside antibiotic. Nebramycin IV has a broad antibacterial spectrum and has a strong effect on Gram-positive and negative bacteria and mycobacteria .

HY-N14579

Racemomycin D	Bacterial Fungal	Infection
Racemomycin D has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture .

HY-114551

Streptothricin E Racemomycin C; Antibiotic S15-1B	Bacterial Fungal	Infection
Racemomycin C has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture .

HY-B0210R

Cefoperazone (Standard)	Bacterial Antibiotic	Infection
Cefoperazone (Standard) is the analytical standard of Cefoperazone. This product is intended for research and analytical applications. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .

HY-108279

Ulifloxacin	Antibiotic Bacterial	Infection
Ulifloxacin is a broad-spectrum quinolone antibiotic. Ulifloxacin is the active metabolite of Prulifloxacin (HY-B0024). Ulifloxacin has anti-bacterial activity .

Cat. No.	Product Name	Type

HY-D0027

7-Amino-4-methylcoumarin

Coumarin 120; AMC

Fluorescent Dyes/Probes

7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively.

HY-D0027R

7-Amino-4-methylcoumarin (Standard)

Fluorescent Dyes/Probes

7-Amino-4-methylcoumarin (Standard) is the analytical standard of 7-Amino-4-methylcoumarin. This product is intended for research and analytical applications. 7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively. [4]

Cat. No.	Product Name	Type

HY-W250302

Methylbenzethonium chloride

Biochemical Assay Reagents

Methylbenzethonium chloride is a quaternary ammonium compound commonly used as a preservative and disinfectant in a variety of personal care and healthcare products. Methylbenzethonium chloride has several properties that make it suitable for these applications, including its broad-spectrum antibacterial activity against bacteria, viruses and fungi. In addition, it is used as a preservative in cosmetic and pharmaceutical formulations to prevent the growth of microorganisms.

HY-W250308

ε-Poly-L-lysine (MW 3800-4200)

Epsilon-polylysine (MW 3800-4200); ε-Polylysine (MW 3800-4200); ε-PL (MW 3800-4200)

Cell Assay Reagents

Epsilon-polylysine is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine is also used as a liposome stabilizer .

HY-W250308A

ε-Poly-L-lysine (hydrochloride) (MV 2000-5000)

Epsilon-polylysine (hydrochloride) (MV 2000-5000); ε-Polylysine (hydrochloride) (MV 2000-5000); ε-PL (hydrochloride) (MV 2000-5000)

Cell Assay Reagents

ε-Poly-L-lysine hydrochloride (MV 2000-5000) is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine hydrochloride inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine hydrochloride has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine hydrochloride can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine hydrochloride is also used as a liposome stabilizer .

HY-W740053

Meropenem sodium	Microbial Culture
Meropenem sodium is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem sodium has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL) .

HY-W250302R

Methylbenzethonium (chloride) (Standard)

Biochemical Assay Reagents

Methylbenzethonium (chloride) (Standard) is the analytical standard of Methylbenzethonium (chloride). This product is intended for research and analytical applications. Methylbenzethonium chloride is a quaternary ammonium compound commonly used as a preservative and disinfectant in a variety of personal care and healthcare products. Methylbenzethonium chloride has several properties that make it suitable for these applications, including its broad-spectrum antibacterial activity against bacteria, viruses and fungi. In addition, it is used as a preservative in cosmetic and pharmaceutical formulations to prevent the growth of microorganisms.

Cat. No.	Product Name	Target	Research Area

HY-P3459A

Tet-213 TFA	Bacterial	Infection
Tet-213 TFA is a antimicrobial peptide. Tet-213 TFA has broad spectrum antibacterial activity. Tet-213 TFA can promote infected wound repair .

HY-P2460

SMAP-29	Bacterial Fungal	Infection Inflammation/Immunology
SMAP-29, a promising antiinfective agent, is a broad spectrum antibacterial and antifungal α-helical cathelicidin-derived peptide. SMAP-29 acts by permeabilizing bacterial membranes and inducing remarkable changes in the surface morphology of susceptible microorganism .

HY-P3459

Tet-213	Bacterial	Infection
Tet-213 is a antimicrobial peptide. Tet-213 has broad spectrum antibacterial activity. Tet-213 can promote infected wound repair .

HY-P5691

P1	Bacterial	Infection Cancer
P1 is a broad-spectrum antimicrobial peptide. P1 shows antibacterial activity against Gram-positive and Gram-negative bacteria,such as B. anthracis spores and Carbapenem-resistant A. baumannii and K. pneumoniae .

HY-P5561

Aurein 2.2	Antibiotic Bacterial	Infection
Aurein 2.2 is a major component of the skin secretion of L.aurea. Aurein 2.2 is an antibiotic with broad-spectrum antibacterial activity against Gram positive bacteria such as Staphylococcus aureus and S. epidermidis .

HY-P10431

Hc-CATH Sea snake cathelicidin	Bacterial	Infection Inflammation/Immunology
Hc-CATH (Sea snake cathelicidin) is an antibacterial peptide with broad-spectrum. Hc-CATH inhibits Shigella dysenteriae and Klebsiella pneumoniae with MIC of 0.16 mM-20.67 mM. Hc-CATH exhibits anti-inflammatory efficacy .

HY-P10228

S-Thanatin	Fungal Bacterial	Infection
S-Thanatin is an insect antimicrobial peptide with potent broad-spectrum antibacterial activity. S-Thanatin can inhibit the activity of Gram-negative bacteria, Gram-positive bacteria, and fungi, without cytotoxicity. The antibacterial activity of S-Thanatin is not affected by PH value, but monovalent cations (Na ⁺/K ⁺) can reduce its antibacterial activity against Gram-negative bacteria in a dose-dependent manner .

HY-P5724

Nv-CATH	Bacterial	Infection
Nv-CATH is an *antibacterial* peptide of frog origin. Nv-CATH has broad-spectrum antibacterial activity against gram-positive and gram-negative bacteria. Nv-CATH significantly protects mice from fatal infections caused by Staphylococcus aureus. Nv-CATH protects mice from bacterial infection through antimicrobial immunoregulatory duality .

HY-P3350

LS-BF1	Bacterial	Infection
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N3139

Ombuin	Infection Flavonols Flavonoids Classification of Application Fields Source classification Rutaceae Phenols Polyphenols Plants Disease Research Fields Zanthoxylum armatum DC.	Bacterial
Ombuin, isolated from Zanthoxylum armatum, displays broad spectrum *antibacterial* effect with MIC ranges from 125 to 500 μg/mL .

HY-N7111

Sultamicillin tosylate Sultamicillin (tosilate)	Infection Classification of Application Fields Disease Research Fields	Bacterial Antibiotic
Sultamicillin tosylate is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .

HY-N7125

Cinnamyl acetate	Structural Classification Liliaceae Classification of Application Fields Simple Phenylpropanols Source classification Other Diseases Phenylpropanoids Allium sativum Linn. Plants Disease Research Fields	Bacterial
Cinnamyl acetate has a wide application in the flavor and fragrance industry . Cinnamyl acetate is a new broad spectrum antibacterial agent .

HY-N14967

Epicillin	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Epicillin is found in the strain of Semisynthetic broad-spectrum penicillin with antibacterial activities .

HY-N14308

Aspiculamycin	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Aspiculamycin, a cytosine nucleoside, is an antibiotic. Aspiculamycin has a broad spectrum of antibacterial activity .

HY-N14168

Ashimycin A	Structural Classification Natural Products Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Ashimycin A is a Streptomycin (HY-B1906) analogue with a broad-spectrum antibacterial activity .

HY-N14187

Aspergillic acid	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Aspergillic acid is an antibiotic found in Aspergillus flavus. Aspergillic acid has a broad spectrum of antibacterial activity .

HY-N14170

Ashimycin B	Structural Classification Natural Products Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Ashimycin B is a Streptomycin (HY-B1906) analogue with a broad-spectrum antibacterial activity .

HY-N14192

Maltophilin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Fungal
Maltophilin is a broad-spectrum antifungal antibiotic that has no antibacterial effect against Gram-positive and Gram-negative bacteria .

HY-N14485

Nebramycin Ⅳ	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Nebramycin IV is an aminoglycoside antibiotic. Nebramycin IV has a broad antibacterial spectrum and has a strong effect on Gram-positive and negative bacteria and mycobacteria .

HY-N14579

Racemomycin D	Structural Classification Natural Products Microorganisms Source classification	Bacterial Fungal
Racemomycin D has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture .

HY-114551

Streptothricin E Racemomycin C; Antibiotic S15-1B	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial Fungal
Racemomycin C has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture .

HY-N14753

Juglomycin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Juglomycin A has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg .

HY-N14754

Juglomycin B	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Juglomycin B has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg .

HY-N14491

Coumamidine γ2	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Coumamidine γ2 is a kind of alkaline sugar Cinodine antibiotic, which has broad spectrum antibacterial activity and also has effect on pseudomonas aeruginosa .

HY-N14490

Coumamidine γ1	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Coumamidine γ1 is a kind of alkaline sugar Cinodine antibiotic, which has broad spectrum antibacterial activity and also has effect on pseudomonas aeruginosa .

HY-117108

Nocardicin A	Structural Classification Microorganisms Antibiotics Source classification Beta-lactam Antibiotics	Antibiotic Bacterial
Nocardicin A is a beta-lactam antibiotic with selective antibacterial activity. Nocardicin A has moderate antibacterial activity against a broad spectrum of Gram-negative bacteria including Proteus and Pseudomonas; it has no inhibitory effect on Staphylococcus, Mycobacterium, fungi, and yeast .

HY-B1802A

Tosufloxacin tosylate hydrate 2 Publications Verification A-61827 tosylate hydrate; T-3262	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Tosufloxacin tosylate hydrate (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .

HY-N7449

Neamine	Infection Cardiovascular Disease Classification of Application Fields Disease Research Fields	Antibiotic Bacterial
Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities .

HY-126462

Lantic acid	Triterpenes Structural Classification Terpenoids Verbenaceae Source classification Plants Lantana camaraLinn.	Bacterial
Lantic acid is a triterpenoid compound possessing antimicrobial activity. Lantic acid exhibits inhibitory effects on a broad range of both Gram-positive and Gram-negative bacteria, with particular potency against Escherichia coli and Bacillus subtilis. Lantic acid is utilized in the research and development of antimicrobial agents .

HY-128514

Minimycin Oxazinomycin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Minimycin (Oxazinomycin) is a nucleoside antibiotic with a broad-spectrum antibacterial activity. Minimycin has inhibitory effect on mouse Ehrlich ascites carcinoma, ascites type and solid type sarcoma-180 .

HY-N7125R

Cinnamyl acetate (Standard)	Structural Classification Liliaceae Simple Phenylpropanols Source classification Phenylpropanoids Allium sativum Linn. Plants	Bacterial
Cinnamyl acetate (Standard) is the analytical standard of Cinnamyl acetate. This product is intended for research and analytical applications. Cinnamyl acetate has a wide application in the flavor and fragrance industry . Cinnamyl acetate is a new broad spectrum antibacterial agent .

HY-W018025

5,6-Dihydroxyindole	Structural Classification Natural Products Classification of Application Fields Source classification Phenols Polyphenols Endogenous metabolite Inflammation/Immunology Disease Research Fields	Bacterial Fungal Parasite Endogenous Metabolite
5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum *antibacterial, antifungal, antiviral, antiparasitic* activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens .

HY-16468

Squalamine MSI-1256	Infection Triterpenes Structural Classification Animals Classification of Application Fields Terpenoids Marine natural products Other marine organisms Disease Research Fields Cancer	Bacterial HBV FAK Dengue Virus
Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson ^,s disease mouse models .

HY-59097

(E/Z)-Tapinarof (E/Z)-WBI-1001; (E/Z)-Benvitimod; (E/Z)-GSK2894512	Structural Classification Microorganisms Antibiotics Source classification Phenols Polyphenols	Antibiotic Bacterial Fungal
(E/Z)-Tapinarof ((E/Z)-WBI-1001; 3,5-dihydroxy-4-isopropylstilbene) is a broad-spectrum antibiotic. (E/Z)-Tapinarof has anti-bacterial, anti-fungal and anti-nematode activities .

HY-N15113

Piptamine	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Piptamine has broad antibacterial spectrum, it inhibits Staphylococcus aureus, enterococcus faecalis, Bacillus subtilis, Escherichia coli, Candida albicans with MICs (μg/mL) of 0.78-6.25, 1.56, 1.00, 12.5, 6.25, respectively .

HY-B0529R

Azlocillin (Standard)	Microorganisms Source classification	Bacterial Parasite Antibiotic
Azlocillin (Standard) is the analytical standard of Azlocillin. This product is intended for research and analytical applications. Azlocillin, an antibiotic, is a semisynthetic penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection .

HY-B0956A

Paromomycin Aminosidine	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial Parasite
Paromomycin (Aminosidine) is a broad-spectrum antibiotic. Paromomycin can be used for the study of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. Paromomycin is also used as a therapeutic against visceral leishmaniasis. Paromomycin has antibacterial, antiprotozoal, anthelminthic and antiparasitic effects .

HY-B1802AR

Tosufloxacin tosylate hydrate (Standard) A-61827 tosylate hydrate (Standard); T-3262 (Standard)	Structural Classification Microorganisms Antibiotics Source classification Antibacterial Disease Research Other Antibiotics	Reference Standards Bacterial Antibiotic
Tosufloxacin (tosylate hydrate) (Standard) is the analytical standard of Tosufloxacin (tosylate hydrate). This product is intended for research and analytical applications. Tosufloxacin tosylate hydrate (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria[1][2].

HY-N8213

Rapanone	Infection Quinones Structural Classification Classification of Application Fields Source classification Benzene Quinones Embelia laeta (Linn.) Mez Plants Myrsinaceae Inflammation/Immunology Disease Research Fields	Apoptosis Phospholipase Bacterial Parasite
Rapanone is a natural benzoquinone. Rapanone exhibits a broad spectrum of biological actions, including anti-tumor, antioxidant, anti-inflammatory, antibacterial and antiparasitic. Rapanone also is a potent and selective human synovial PLA₂ inhibitor, with an IC₅₀ of 2.6 μM .

HY-N7112

Leucomycin Kitasamycin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Leucomycin (Kitasamycin) is an orally active macrolide antibiotic produced by Streptomyces kitasatoensis. Leucomycin has broad-spectrum antibacterial activities against gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae and some larger viruses .

HY-137139

10'-Desmethoxystreptonigrin	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial Farnesyl Transferase
10'-Desmethoxystreptonigrin is an inhibitor for Ras Farnesyltransferase with an IC₅₀ of 21 μM. 10'-Desmethoxystreptonigrin is a broad-spectrum antibiotic with antibacterial activity. 10'-Desmethoxystreptonigrin exhibits antitumor activity against P388 leukemia, without significant cytotoxicity (LD₅₀ is 8.8 mg/kg) .

HY-W018025R

5,6-Dihydroxyindole (Standard)	Structural Classification Natural Products Source classification Phenols Polyphenols Endogenous metabolite	Bacterial Fungal Parasite Endogenous Metabolite
5,6-Dihydroxyindole (Standard) is the analytical standard of 5,6-Dihydroxyindole. This product is intended for research and analytical applications. 5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens .

HY-130066

Fortimicin C	Structural Classification Microorganisms Source classification Saccharides Monosaccharides	Antibiotic Bacterial
Fortimicin C is an antibiotic, which can be isolated from Micromonospora olivoasterospora. Fortimicin C exhibits broad-spectrum antibacterial activity, inhibits Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumoniae, Salmonella typhosa and Serratia marcescens, with MICs of 0.16-0.64 μg/mL. Fortimicin C is resistant against aminoglycoside inactivating enzymes .

HY-13678

Meropenem Maximum Cited Publications 15 Publications Verification SM 7338	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Beta-lactam Antibiotics	Penicillin-binding protein (PBP) Bacterial Antibiotic
Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL) .

HY-N7224

N-Formylfortimicin A SF-1854	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial Antibiotic
N-Formylfortimicin A (SF-1854) is an aminoglycoside antibiotic with broad-spectrum antibacterial activity. It primarily acts on bacterial ribosomes to inhibit protein synthesis and exhibits notable inhibitory effects against various Gram-positive and Gram-negative bacteria (e.g., E. coli with a MIC of 12.5-50 μg/mL), making it a potential candidate for research on bacterial infection-related diseases .

HY-B0239

Chloramphenicol 5+ Cited Publications	Structural Classification Classification of Application Fields Anti-aging Source classification Antibacterial Disease Research Endogenous metabolite Other Antibiotics Infection Human Gut Microbiota Metabolites Plant Cell Culture Microorganisms Antibiotics Resistance Selection Animal Husbandry Anticancer Disease Research Fields Cancer	Antibiotic Bacterial HIF/HIF Prolyl-Hydroxylase VEGFR Autophagy Apoptosis Beclin1 JNK Akt MMP
Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows *antibacterial* activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .

HY-B0239R

Chloramphenicol (Standard)	Structural Classification Source classification Antibacterial Disease Research Endogenous metabolite Other Antibiotics Human Gut Microbiota Metabolites Plant Cell Culture Microorganisms Antibiotics Resistance Selection Animal Husbandry Anticancer	Antibiotic Bacterial HIF/HIF Prolyl-Hydroxylase VEGFR Autophagy Apoptosis Beclin1 JNK Akt MMP
Chloramphenicol (Standard) is the analytical standard of Chloramphenicol. This product is intended for research and analytical applications. Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .

HY-B0147

Pefloxacin 2 Publications Verification Pefloxacinium	Infection Classification of Application Fields Disease Research Fields	Antibiotic Bacterial Parasite DNA/RNA Synthesis Topoisomerase
Pefloxacin is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC₅₀ of 45 μg/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC₉₀s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti-Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies .

HY-126637

Marasmic acid	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial Fungal
Marasmic acid is a sesquiterpenoid with unsaturated dialdehyde functionality, first isolated from the Basidiomycete Marasmus conigenus. Marasmic acid has antibacterial, antifungal, cytotoxic and mutagenic activities, and its broad-spectrum activity is related to the α,β-unsaturated aldehyde group. However, its detailed biological mechanism of action has not been clarified. Previous studies have suggested that marasmic acid may exert its effects by reacting with endogenous nucleophiles or forming pyrrole derivatives. This study found that marasmic acid interferes with the membrane sensor histidine kinase MoSln1p of M. oryzae, superactivates the HOG pathway and causes cell death, indicating that its mechanism of action is different from other unsaturated dialdehyde sesquiterpenoids.

Cat. No.	Product Name	Chemical Structure

HY-B0210S

Cefoperazone-d5
Cefoperazone-d₅ is deuterium labeled Cefoperazone. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .

HY-16980S

Eravacycline-d4 dihydrochloride
Eravacycline-d₄ (TP-434-d₄) dihydrochloride is deuterium labeled Eravacycline. Eravacycline is a potent and broad-spectrum *antibacterial* agent .

HY-B1805S

Triclocarban-d4

Triclocarban-d₄ is the deuterium labeled Triclocarban. Triclocarban (3,4,4′-Trichlorocarbanilide), a broad spectrum antibacterial compound, is widely used in a broad range of applications such as the production of soaps, skin creams, toothpastes and deodorants. Triclocarban is a potential endocrine-disrupting chemical with the capacity to modulate androgen and estrogen activities as well as other hormone-mediated biological processes .

HY-135393S

Sulfadimethoxypyrimidine-d4
Sulfadimethoxypyrimidine-d₄ is a deuterium labeled Sulfadimethoxypyrimidine. Sulfadimethoxypyrimidine is a sulfonamide antibiotic with a broad-spectrum antibacterial effect .

HY-N7125S

Cinnamyl acetate-13C2
Cinnamyl acetate- ¹³C₂ is ¹³C labeled Cinnamyl acetate (HY-N7125). Cinnamyl acetate has a wide application in the flavor and fragrance industry . Cinnamyl acetate is a new broad spectrum antibacterial agent .

HY-B1374S2

Florfenicol-13C6
Florfenicol- ¹³C₆ (SCH-25298- ¹³C₆) is ¹³C labeled Florfenicol. Florfenicol ((-)-Florfenicol) is an orally active broad-spectrum antibacterial antibiotic with anti-inflammatory, pro apoptotic, and immunomodulatory functions .

HY-N0565AS

Doxycycline-d3 hydrochloride
Doxycycline-d₃ hydrochloride is deuterium labeled Doxycycline (hydrochloride). Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hydrochloride shows antibacterial activity and anti-cancer cell proliferation activity .

HY-N0565S3

Doxycycline-13C,d3
Doxycycline- ¹³C,d₃ is ¹³C and deuterium labeled Doxycycline. Doxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline shows antibacterial activity and anti-cancer cell proliferation activity .

HY-W585956

Triclocarban-13C6

Triclocarban- ¹³C₆ is the ¹³C labeled isotope of Triclocarban (HY-B1805). Triclocarban (3,4,4′-Trichlorocarbanilide), a broad spectrum antibacterial compound, is widely used in a broad range of applications such as the production of soaps, skin creams, toothpastes and deodorants. Triclocarban is a potential endocrine-disrupting chemical with the capacity to modulate androgen and estrogen activities as well as other hormone-mediated biological processes .

HY-B0458AS

Cefprozil-d4
Cefprozil-d₄ is the deuterium labeled Cefprozi (HY-B0458A) . Cefprozil is a second-generation cephalosporin type antibiotic. Cefprozil exhibits broad-spectrum antibacterial activity, and is orally active. Cefprozil can be used for the study of pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections .

HY-W653936

Cephalexin-d5 hydrate

Cephalexin-d₅ (hydrate) is deuterium labeled Cephalexin (monohydrate). Cephalexin (Cefalexin) monohydrate is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) monohydrate targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al .

HY-B1805S1

Triclocarban-13C13

Triclocarban- ¹³C₁₃ (3,4,4'-Trichlorocarbanilide- ¹³C₁₃) is ¹³C labeled Triclocarban. Triclocarban (3,4,4′-Trichlorocarbanilide), a broad spectrum antibacterial compound, is widely used in a broad range of applications such as the production of soaps, skin creams, toothpastes and deodorants. Triclocarban is a potential endocrine-disrupting chemical with the capacity to modulate androgen and estrogen activities as well as other hormone-mediated biological processes .

HY-13678S

Meropenem-d6
Meropenem-d₆ is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .

HY-N7101S1

Cefpodoxime Proxetil-d6

Cefpodoxime Proxetil-d₆ (U-76,252-d₆) is deuterium labeled Cefpodoxime Proxetil. Cefpodoxime proxetil is an orally administered broad spectrum third-generation cephalosporin. Cefpodoxime proxetil has anti-bacterial activity. Cefpodoxime proxetil binds to penicillin binding proteins (PBPs) which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis .

HY-10581AS

Gatifloxacin-d3 hydrochloride

Gatifloxacin-d₃ (hydrochloride) is the deuterium labeled Gatifloxacin (hydrochloride). Gatifloxacin hydrochloride (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin hydrochloride can be used to treat bacterial conjunctivitis in vivo.

HY-B0330DS

(R)-Ofloxacin-d3

(R)-Ofloxacin-d₃ is the deuterium labeled (R)-Ofloxacin. (R)-Ofloxacin is the dextrorotatory enantiomer of Ofloxacin (HY-B0125) and is an orally effective fluoroquinolone antibiotic. (R)-Ofloxacin can inhibit the activity of bacterial DNA topoisomerase II, interfere with bacterial DNA replication and repair, and exert a bactericidal effect. (R)-Ofloxacin has a broad-spectrum antibacterial activity and has inhibitory effects on both Gram-negative and Gram-positive bacteria .

HY-13678S1

Meropenem-d6-1
Meropenem-d6-1 (SM 7338-d6-1) is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .

HY-W740028

Cefditoren-d3 sodium

Cefditoren-d₃ (sodium) (ME 1206-d₃) is deuterium labeled Cefditoren (sodium). Cefditoren sodium (ME 1206) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren sodium has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren sodium can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .

HY-17452AS

Cefditoren Pivoxil-d3

Cefditoren Pivoxil-d₃ (Cefditoren pivoxyl-d₃) is deuterium labeled Cefditoren Pivoxil. Cefditoren Pivoxil (ME 1207) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren Pivoxil has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren Pivoxil can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .

HY-B0239S2

Threo-Chloramphenicol-d6

Threo-Chloramphenicol-d₆ is the deuterium labeled Chloramphenicol . Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .

HY-W653962

Triclosan-13C6

Triclosan- ¹³C₆ is ¹³C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC₅₀s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .

HY-W747491

Triclosan-13C12

Triclosan- ¹³C₁₂ is ¹³C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC₅₀s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .

HY-B0147S

Pefloxacin-d5

Pefloxacin-d₅ is the deuterium labeled Pefloxacin (HY-B0147). Pefloxacin is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC₅₀ of 45 μg/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti-Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies .

HY-B0712S1

Ceftriaxone-13C2,d3 triethylammonium salt

Ceftriaxone- ¹³C₂,d₃ triethylammonium salt is ¹³C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC₅₀ value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .

HY-W015490S

1,4-Naphthoquinone-d6

1,4-Naphthoquinone-d₆ is the deuterium labeled 1,4-Naphthoquinone. 1,4-Naphthoquinone is an inhibitor with broad-spectrum inhibitory activity targeting DNA polymerase, NF-κB and monoamine oxidase (MAO-A/B), with antibacterial and anti-biofilm efficacy. 1,4-Naphthoquinone is a competitive inhibitor of MAO-B (Ki=1.4 μM) and a non-competitive inhibitor of MAO-A (Ki=7.7 μM). 1,4-Naphthoquinone inhibits DNA polymerase pol α, β, γ, δ, ε, λ with IC₅₀ ranging from 5.57-128 μM. 1,4-Naphthoquinone inhibits tumor cell proliferation, induces apoptosis and necrosis, and has anti-angiogenic and anti-inflammatory activities by inducing oxidative stress, depleting glutathione (GSH), inhibiting DNA polymerase-mediated DNA synthesis and blocking NF-κB nuclear translocation. 1,4-Naphthoquinone can be used in anti-bacterial , anti-tumor and anti-inflammatory studies, including inhibition of melanoma and colon cancer cell growth and endothelial cell function, as well as LPS-induced inflammation models .

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