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Results for "
branches
" in MedChemExpress (MCE) Product Catalog:
35
Biochemical Assay Reagents
18
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N0771
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Endogenous Metabolite
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Cardiovascular Disease
Metabolic Disease
Inflammation/Immunology
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L-Isoleucine is an orally active branched chain amino acid, which is the L-enantiomer of isoleucine. L-Isoleucine has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. L-Isoleucine regulates the inflammatory response to protect against pathogens in vivo and in vitro .
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- HY-N0771R
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Reference Standards
Endogenous Metabolite
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Cardiovascular Disease
Metabolic Disease
Inflammation/Immunology
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L-Isoleucine (Standard) is the analytical standard of L-Isoleucine. This product is intended for research and analytical applications. L-Isoleucine is an orally active branched chain amino acid, which is the L-enantiomer of isoleucine. L-Isoleucine has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. L-Isoleucine regulates the inflammatory response to protect against pathogens in vivo and in vitro .
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- HY-E70029
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Others
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Others
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alpha-1,6-Fucosidase (LpAlfC(E274A)) (EC 3.2.1.51) cleaves branched non-reducing terminal fucose, linked α(1-6) to the core N-acetylglucosamine of N-linked oligosaccharides. alpha-1,6-Fucosidase (LpAlfC(E274A)) is useful for determining core fucosylation .
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- HY-E70124A
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- HY-E70124C
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- HY-107237
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Others
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Others
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Broussonetine A is a pyrrolidine alkaloid compound isolated from the branches of Broussonetia kazinoki Sieb .
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- HY-157270
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Liposome
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Others
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2-Heptylundecanol is a branched chain aliphatic alcohol which can be used in the synthesis of nano lipid particles .
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- HY-P3743
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Src
Others
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Others
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p60c-src Substrate is an efficient and specific substrate for p60c-src protein tyrosine kinase (PTK). p60c-src Substrate can be used to synthesize chimeric branched peptides .
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- HY-P10007
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Z-GPFL-CHO
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Proteasome
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Cancer
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Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde that acts as a highly selective and potent proteasomal inhibitor (Ki = 1.5 µM for branched chain amino acid preferring, 2.3 µM for small neutral amino acid preferring, and 40.5 µM for chymotrypsin-like activities; IC50 = 3.1 µM for peptidyl-glutamyl peptide hydrolyzing activity) .
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- HY-E70297
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MGAT4A
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Endogenous Metabolite
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Cancer
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N-Acetylglucosaminyltransferase IVa (MGAT4A) is a glycosyltransferase that can enhance the migration, invasion, and adhesion abilities of cancer cells, and increase β1,4GlcNAc branched glycans on integrin β1 (ITGB1), a tumor-associated glycoprotein closely related to cell motility .
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- HY-132275
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Biochemical Assay Reagents
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Others
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After the Long trebler phosphoramidite is condensed by the triple condensate, three DNA branches begin to grow simultaneously with each step of the synthesis. Deblock of this construct gives rise to DNA containing a branching point. One arm (stem) is attached to the branch point with its 5'-end, and other arms (branches) are attached with their 3'-ends. Reverse amidites can be used to prepare constructs with different branch orientations.
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- HY-W250110
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Biochemical Assay Reagents
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Infection
Others
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Polyethylenimine (branched) (30% in water) is a organic macromolecule with high cationic-charge-density potential. Polyethylenimine (branched) (30% in water) can ensnare DNA as well as attach to cell membrane. Polyethylenimine (branched) (30% in water) also retains a substantial buffering capacity at virtually any pH. Polyethylenimine (branched) (30% in water) is widely used as transfection reagent .
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- HY-W250110I
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PEI (branched) (MW 10000)
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Biochemical Assay Reagents
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Others
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Polyethylenimine (branched) (MW 10000) (PEI (branched) (MW 10000)) is a cationic polymer widely used as a nonviral nucleotide delivery reagent .
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- HY-W741062
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iso-C17:0; Isoheptadecasphinganine; 15-Methylhexadecasphinganine
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Bacterial
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Infection
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Sphinganine (d16:0 branched) is an iso-branched sphingolipid. It has been found as a component of ceramide-containing phospholipids in bacteria.
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- HY-138123
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Biochemical Assay Reagents
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Others
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Fmoc-Glu(OtBu)-OSu is used for synthesizing N3S chelators and double branched and triple branched carboxyl terminated polyethylene glycol reagents .
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- HY-159648
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Endogenous Metabolite
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Cardiovascular Disease
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PF-07328948 is an orally effective BDK (branch chain ketoacid dehydrogenase kinase) inhibitor, with IC50 of 110 nM. PF-07328948 acts as a BCKDH (branch chain ketoacid dehydrogenase) enzyme complex degrader to enhance BCAA (branch chain amino acid) catabolism. PF-07328948 improves metabolic and heart failure end points in rats .
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- HY-W009371A
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Endogenous Metabolite
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Metabolic Disease
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D-Ribose 5-phosphate is an intermediate of the oxidative branch of the pentose phosphate pathway (PPP) and an end product of the nonoxidative branch of the PPP. D-Ribose 5-phosphate is used in the synthesis of nucleotides and nucleic acids .
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- HY-158861
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G1-nPr-C14E
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Liposome
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Others
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C3-K2-E14 is a multi-ionizable amino-lipid featuring a central tertiary amine with two identical branches and an n-propyl group. Each branch features a propanamide linking to a branched amine, each with two C14 arms and a hydroxyl. Ionizable lipids such as this may be applied in the development of lipid nanoparticles for drug discovery.
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- HY-W800687
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Biochemical Assay Reagents
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Others
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Tetra(3-methoxy-n-(prop-2-ynyl)propanamide) methane is a 4-branched molecule with propargyl groups that can be linked to azide-containing biomolecules via Click Chemistry.
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- HY-W009371
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DNA/RNA Synthesis
Endogenous Metabolite
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Metabolic Disease
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D-Ribose 5-phosphate disodium is an intermediate of the oxidative branch of the pentose phosphate pathway (PPP) and an end product of the nonoxidative branch of the PPP. D-Ribose 5-phosphate disodium is used in the synthesis of nucleotides and nucleic acids .
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- HY-W009371C
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Endogenous Metabolite
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Metabolic Disease
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D-Ribose 5-phosphate disodium dihydrate is an intermediate of the oxidative branch of the pentose phosphate pathway (PPP) and an end product of the nonoxidative branch of the PPP. D-Ribose 5-phosphate is used in the synthesis of nucleotides and nucleic acids .
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- HY-W587796
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6-PGδL; 6-Phosphonoglucono-D-lactone
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Endogenous Metabolite
PDI
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Cardiovascular Disease
Metabolic Disease
Cancer
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6-Phosphoglucono-δ-lactone (6-PGδL) is a reversal substrate of glucose-6-phosphate dehydrogenase (G6PD). 6-Phosphoglucono-δ-lactone is an intermediate compound in the oxidative branch of the pentose phosphate pathway (PPP). 6-Phosphoglucono-δ-lactone produced from D-glucose-6-phosphate by glucose-6-phosphate dehydrogenase (G6PDH) and is converted to 6-phosphoglutonate by lactonase. 6-Phosphoglucono-δ-lactone can be used for heart failure, type 2 diabetes and cancers research .
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- HY-W762023
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- HY-N3337
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Others
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Others
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Macrocarpal L is a Sesquiterpenoids product that can be isolated from the branches of Eucalyptus globulus .
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- HY-N3611
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Others
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Others
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Codaphniphylline is a Alkaloids product that can be isolated from the branches of Daphniphyllum macropodum Miq. .
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- HY-N3406
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(+)-Lansiumarin C; 5-Demethoxymelicotriphyllin C
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Others
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Others
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Lansiumarin C, a lansiumarin, can be isolated from the branches of Clausena lansium (Rutaceae) .
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- HY-N3681
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Others
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Others
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Daphmacropodine is a Alkaloids product that can be isolated from the branches of Daphniphyllum macropodum Miq. .
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- HY-N3525
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Others
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Others
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Calyciphylline A is a Alkaloids product that can be isolated from the branches of Daphniphyllum macropodum Miq. .
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- HY-N3684
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Others
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Others
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Daphnilongeridine is a Alkaloids product that can be isolated from the branches of Daphniphyllum macropodum Miq. .
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- HY-N7711
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Others
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Others
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5-Epicanadensene is a Diterpenoids product that can be isolated from the branches of Taxus sumatrana. .
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- HY-N8867
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Others
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Others
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13-Deacetyltaxachitriene A is a Diterpenoids product that can be isolated from the branches of Taxus sumatrana .
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- HY-118792
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Endogenous Metabolite
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Cancer
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AHR activator 1 is an aryl hydrocarbon receptor activator with activity regulating fibroblast growth factor-2 (FGF2)-induced branching morphogenesis. AHR activator 1 prevents the formation of cellular branches by inhibiting AHR signaling. AHR activator 1 also associates with adhesion of dissociated linkers, suggesting the importance of dissociated linkers in the inhibition of branching by AHR agonists. Studies of AHR activator 1 reveal its functional role in mammary gland morphogenesis and play a role in inhibiting FGF-induced invasion .
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- HY-N9035
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Others
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Others
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20-Deacetyltaxuspine X is a Diterpenoids product that can be isolated from the branches of Taxus sumatrana. .
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- HY-CE01041
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- HY-N8865
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Others
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Others
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2-Deacetyltaxuspine X is a Diterpenoids product that can be isolated from the branches of Taxus sumatrana .
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- HY-W127484
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14-Methylpentadecanoic acid
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Biochemical Assay Reagents
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Others
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14-Methylpentadecanoic acid is a branched-chain fatty acid that has been found in soil bacteria. 1,2
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- HY-120894
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- HY-W015641
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Others
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Others
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2,2-Dimethylsuccinic acid belongs to the class of organic compounds known as methyl-branched fatty acids.
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- HY-N0486
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- HY-N8927
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Others
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Others
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4'-O-Demethylbroussonin A is a Phenols product that can be isolated from the branches of Broussonetia papyrifera .
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- HY-CE01040
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- HY-160569
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- HY-N7349
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Others
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Others
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N-Methyltaxol C is a Diterpenoids product that can be isolated from the branches of Taxus Chinensis var.Mairei. .
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- HY-N3453
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Others
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Others
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Isotaxiresinol 9,9'-acetonide is a Lignans product that can be isolated from the branches of Taxus wallichiana .
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- HY-N3644
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Others
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Others
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Cryptomeridiol 11-rhamnoside is a Sesquiterpenoids product that can be isolated from the branches of Eucalyptus globulus Labill. .
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- HY-CE01316
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- HY-CE01044
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- HY-W008097
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- HY-W705415A
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Drug Intermediate
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Infection
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(S)-N-methylcoclaurine is a substrate of CyNMCH. (S)-N-methylcoclaurine serves as an important branch point intermediate in benzylisoquinoline alkaloid biosynthesis.
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- HY-N2737
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Others
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Others
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7,3'-Dihydroxy-4'-methoxyflavan is a Flavonoids product that can be isolated from the branches of Broussonetia papyrifera .
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- HY-W250110E
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PEI (branched) (MW 25000)
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Biochemical Assay Reagents
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Others
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Polyethylenimine (branched) (MW 25000) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-121950
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Biochemical Assay Reagents
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Others
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18-Methyleicosanoic acid is a branched-chain fatty acid. 18-Methyleicosanoic acid has a hydrophobic surface and can act as a boundary lubricant .
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- HY-N3595
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TNF Receptor
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Inflammation/Immunology
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Cleomiscosin A is a coumarino-lignoid from branch of Macaranga adenantha. Cleomiscosin A is active against TNF-alpha secretion of the mouse peritoneal macrophages .
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- HY-W800744
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Biochemical Assay Reagents
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Others
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Heptadecan-9-yl 8-(3-hydroxypropylamino)octanoate is a lipid featuring a propanolamine headgroup, an octanoate ester, and a branched C17 tail.
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- HY-N0486S13
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- HY-CE00353
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- HY-CE00349
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- HY-N2691
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Others
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Others
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6,8-Cyclo-1,4-eudesmanediol is a Sesquiterpenoids product that can be isolated from the branches of Eucalyptus robusta Smith .
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- HY-N0486S11
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- HY-N2883
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Apigenin 5-glucoside
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Others
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Inflammation/Immunology
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Salipurpin (Apigenin 5-glucoside) is a flavonoid compound isolated from the branches and leaves of Cephalotaxus fortunei, which has certain anti-inflammatory activity .
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- HY-122410R
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Reference Standards
Cytochrome P450
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Others
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Citraconic acid (Standard) is the analytical standard of Citraconic acid. This product is intended for research and analytical applications. Citraconic acid belongs to the class of organic compounds known as methyl-branched fatty acids.
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- HY-N3345
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Bacterial
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Infection
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Macrocarpal B is an antibacterial compounds. Macrocarpal B can be isolated from the branch of Eucalyptus globulus. Macrocarpal B can be used for the research of periodontal disease .
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- HY-156193
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PDHK
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Cardiovascular Disease
Metabolic Disease
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PF-07208254 is a selective, orally active allosteric inhibitor of branched-chain ketoacid dehydrogenase kinase (BDK) (IC50=110 nM, Ki=54 nM, KD=84 nM). PF-07208254 inhibits BDK-mediated BCKDH phosphorylation and enhances the catabolism of branched-chain amino acids (BCAAs) and branched-chain keto acids (BCKAs) by binding to the allosteric pocket of BDK, reducing BDK binding to BCKDH-E2 and promoting BDK degradation. PF-07208254 inhibits BDK activity in human skeletal muscle cells (IC50=540 nM) and has activity to improve cardiac function and metabolism. PF-07208254 can be used in the study of cardiometabolic diseases (e.g., heart failure, type 2 diabetes) .
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- HY-W800717
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Biochemical Assay Reagents
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Others
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Tetra-(amido-PEG10-azide) is a branched PEG linker with four terminal azide groups. The azide groups enable PEGylation via Click Chemistry.
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- HY-N1289
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Fungal
Phosphodiesterase (PDE)
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Infection
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Sequosempervirin B, a norlignan isolated from the branches and leaves of Sequoia sempervirens, has antifungal properties. Sequosempervirin B has an inhibitory effect on cyclic AMP phosphodiesterase .
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- HY-151507
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Liposome
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Others
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306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .
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- HY-N0486S4
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- HY-N0486S
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- HY-N0486S12
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- HY-N0486S9
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- HY-134422
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Isobutyryl CoA lithium
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Biochemical Assay Reagents
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Others
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Isobutyryl coenzyme A (Isobutyryl CoA) lithium is A coenzyme A involved in the metabolic pathway of fatty acids. Isobutyryl coenzyme A lithium is made by combining isobutyric acid (short chain branched fatty acid) with coenzyme A.
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- HY-111487
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Endogenous Metabolite
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Metabolic Disease
Cancer
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α-methylacyl-CoA racemase 1 is an enzyme that catalyzes a key chiral inversion step in the metabolism of branched-chain fatty acids, and used as a maker in prostate and other cancer.
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- HY-N0486S2
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- HY-W193545A
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ERG240
3 Publications Verification
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Others
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Inflammation/Immunology
Cancer
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ERG240 is an oral active branched-chain amino acid aminotransferase 1 (BCAT1) inhibitor. ERG240 can be used for the research of cancer, rheumatoid arthritis, and bone disease .
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- HY-N3154
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Others
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Cancer
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Odorinol is a natural product isolated from branches and leaves of Aglaia odorata. Odorinol has potential antineoplastic activity and can inhibit both the initiation and promotion stages of skin cancer .
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- HY-N0486S1
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- HY-W800716
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Biochemical Assay Reagents
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Others
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Tri(Azide-PEG10-NHCO-ethyloxyethyl)amine is a branched PEG linker with three terminal azide groups. The azide groups enable PEGylation via Click Chemistry.
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- HY-119109
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Endogenous Metabolite
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Cancer
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Laminaran is an β-1-3-glucan and a typical ligand for Dectin-1 from Eisenia Bicyclis, has potent immunomodulating, radioprotective, and anticancer activities . Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds . Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy .
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- HY-172289
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Biochemical Assay Reagents
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Others
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3,3'-(Propylimino)bis[N-(2-aminoethyl)propanamide] is a branched amine molecule featuring two identical aminoethylpropanamides and a propyl group linked by a central tertiary amine.
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![3,3'-(Propylimino)bis[N-(2-aminoethyl)propanamide]](//file.medchemexpress.eu/product_pic/hy-172289.gif)
- HY-N0486S10
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- HY-N3155
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Roxburghiline
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Others
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Cancer
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Odorine (Roxburghiline) is a natural product isolated from branches and leaves of Aglaia odorata. Odorine has potential antineoplastic activity and can inhibit both the initiation and promotion stages of skin cancer .
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- HY-N0486S3
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- HY-N0486R
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Leucine (Standard)
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Reference Standards
mTOR
Endogenous Metabolite
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Metabolic Disease
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L-Leucine (Standard) is the analytical standard of L-Leucine. This product is intended for research and analytical applications. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
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- HY-N0486S5
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- HY-131503
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13-MTD; 13-Methylmyristic acid
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Apoptosis
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Cancer
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13-Methyltetradecanoic acid (13-MTD), a saturated branched-chain fatty acid with potent anticancer effects. 13-Methyltetradecanoic acid induces apoptosis in many types of human cancer cells .
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- HY-172765
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Endogenous Metabolite
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Metabolic Disease
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10-POHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs). 10-POHSA may be a bioactive lipid with roles in metabolic syndrome and inflammation.
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- HY-121727
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AE 1887196; BCS-BX60309
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Acetolactate Synthase (ALS)
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Others
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Triafamone (AE 1887196) is a paddy field pre-emergence and post-emergence sulfonamide herbicide. Triafamone weeds by
inhibiting the acetolactate synthase (ALS) enzyme, thereby blocking the biosynthesis of branched-chain amino acids .
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- HY-131960A
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Polysucrose 70
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Biochemical Assay Reagents
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Others
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Sucrose-epichlorohydrin copolymer 70 (Polysucrose 70) is a branched polysaccharide polymer with a high molecular weight. Sucrose-epichlorohydrin copolymer 70 is formed by the copolymerization of sucrose and epichlorohydrin, which can be used for cell separation .
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- HY-I1060S
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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L-Alloisoleucine-d10 is the deuterium labeled L-Alloisoleucine. L-Alloisoleucine is a branched chain amino acid and is a stereo-isomer of L-isoleucine. L-Alloisoleucine is a common constituent of human plasma (albeit at low levels).
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- HY-W190930
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Biochemical Assay Reagents
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Others
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t-Butyl 1,5-di(ethoxycarbonyl)pentan-3-ylcarbamate is a branched molecule with an n-Boc group and two ethyl ester moieties. The Boc-protected amine can be deprotected under acidic conditions.
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- HY-N7842
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17-Methylstearic acid; 17-Methyloctadecanoic acid
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Biochemical Assay Reagents
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Others
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17-Methylstearic acid is a methyl-branched fatty acid that has been found in mouse meibomian glands, C. cornucopioides mushrooms, and Phytobacter species. It is also found in the aerial parts of C. ladanifer, where its concentration varies seasonally.
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- HY-N0486S8
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- HY-CE00663
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- HY-N0486S6
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mTOR
Endogenous Metabolite
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Metabolic Disease
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L-Leucine-2- 13C, 15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
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- HY-N9417
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2,3-Dihydroxy-3-methylbutanoic acid
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Endogenous Metabolite
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Others
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2,3-Dihydroxyisovaleric acid (2,3-Dihydroxy-3-methylbutanoic acid) is a natural metabolite of the branched-chain amino acid leucine that has been found present in the urine of a patient with 2-hydroxyglutaric aciduria .
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- HY-W440820
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Liposome
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Cancer
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Bis(bis(2-carboxyethyl)aminopropyl)methylamine is a symmetrical branched linker featuring three tertiary amines and four carboxylic acids. Each carboxylic acid is open to forming esters or amides. It can be used in developing lipid nanoparticles.
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- HY-W015641R
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Reference Standards
Others
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Others
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2,2-Dimethylsuccinic acid (Standard) is the analytical standard of 2,2-Dimethylsuccinic acid. This product is intended for research and analytical applications. 2,2-Dimethylsuccinic acid belongs to the class of organic compounds known as methyl-branched fatty acids.
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- HY-116392E
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- HY-N9113
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Others
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Cardiovascular Disease
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1,3,5,6-Tetrahydroxyxanthone is a natural xanthone that can be isolated from Garcinia achachairu Rusby (Clusiaceae) branches. 1,3,5,6-Tetrahydroxyxanthone induces diuresis and saluresis in normotensive and hypertensive rats .
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- HY-140531A
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Biochemical Assay Reagents
|
Others
|
|
N-(Biotin-PEG4)-N-bis(PEG4-acid) hydrochloride is a branched biotinylation reagent for labeling. The carboxylic acid groups can react with primary amines in the presence of EDC and HATU to form stable amide bonds.
|
-
- HY-N0486S7
-
|
|
mTOR
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Leucine-1- 13C, 15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
|
-
- HY-W010513
-
|
|
Endogenous Metabolite
Bacterial
|
Neurological Disease
|
|
3-Methylvaleric Acid is a branched alkanoic acid. 3-Methylvaleric Acid can be utilized by Pseudomonas citronettotis as a sole carbon source for its growth. 3-Methylvaleric Acid derivatives exhibit anti-hyperalgesic and anticonvulsant activities .
|
-
- HY-W010516
-
|
2-Methylpentanoic acid
|
Endogenous Metabolite
|
Metabolic Disease
|
|
2-Methylvaleric acid is a branched short-chain fatty acid (SCFA) produced by the metabolism of branched-chain amino acids by gut microbes. 2-Methylvaleric acid can be used as a potential biomarker for metabolic diseases such as type 2 diabetes, and its content is significantly reduced in the feces of diabetic mice. 2-Methylvaleric acid may regulate host energy metabolism and inflammatory response through G protein-coupled receptors (GPCRs) or histone deacetylase (HDAC) inhibition. 2-Methylvaleric acid can be used to study gut microbe-host interactions and metabolic diseases as a fecal biomarker[1][2].
|
-
- HY-W721687
-
|
tert-Butylacetic acid-d9
|
Biochemical Assay Reagents
|
Others
|
|
3,3-Dimethylbutyric acid-d9 (tert-Butylacetic acid-d9) is a deuterated derivative of 3,3-Dimethylbutyric acid, which is a short-chain branched carboxylic acid and can be used in organic synthesis .
|
-
- HY-E70140
-
|
EC 2.4.1; A4GNT
|
Antibiotic
|
Infection
|
|
α-1,4-N-Acetylglucosaminyltransferase 4 (EC 2.4.1, A4GNT) catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans and suppresses H. pylori growth .
|
-
- HY-W422402
-
|
|
Acetolactate Synthase (ALS)
|
Others
|
|
Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids .
|
-
- HY-18573
-
|
|
Others
|
Others
|
|
Naxillin is a non-auxin-like molecule, which can promote the lateral root branching in the basal meristem of the root, through the conversion of the auxin precursor indole-3-butyric acid (IBA) to the active auxin indole-3-acetic acid (IAA) .
|
-
- HY-W800688
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Acid-PEG5-Amide-Tri(3-methoxypropanamide-PEG4-Azide) Methane is a branched PEG linker with a terminal carboxylic acid group and three terminal azides. The azide groups enables PEGylation via Click Chemistry.
|
-
- HY-153672
-
|
|
ADC Linker
|
Cancer
|
|
Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 (compound 5) is a branched linker that can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W008097R
-
|
|
Reference Standards
Endogenous Metabolite
|
Metabolic Disease
|
|
3,3-Dimethylglutaric acid (Standard) is the analytical standard of 3,3-Dimethylglutaric acid. This product is intended for research and analytical applications. 3,3-Dimethylglutaric acid, a member of methyl-branched fatty acids, is a endogenous metabolite occasionally found in human urine[1].
|
-
- HY-101045
-
|
|
Drug Derivative
|
Cardiovascular Disease
|
|
AT-112 is a ketotanserin analogue. AT-112 has hemodynamic effects. AT-112 significantly reduces portal vein branch blood flow and portal vein pressure. AT-112 can be used to study the pathogenesis of portal hypertension .
|
-
- HY-W1123922H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG-DSPE (MW 10000) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 10000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174964H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm-PEG-DSPE (MW 10000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 10000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174964E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm-PEG-DSPE (MW 5000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 5000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-N1640
-
|
|
Others
|
Others
|
|
1-O-Deacetyl-2α-hydroxykhayanolide E is a natural product that can be isolated from Swietenia mahagoni. 1-O-Deacetyl-2α-hydroxykhayanolide E is widely distributed in the leaves and branches of Swietenia mahagoni .
|
-
- HY-174964C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm-PEG-DSPE (MW 2000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 2000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-W1123922A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG-DSPE (MW 600) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 600) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174964
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm-PEG-DSPE (MW 400) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 1000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174957
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-DSPE (MW 400) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 400) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174957A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-DSPE (MW 600) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 600) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174964A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm-PEG-DSPE (MW 600) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 600) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-W1123922D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG-DSPE (MW 3400) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 3400) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174957H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-DSPE (MW 10000) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 10000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-W1123922C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG-DSPE (MW 2000) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 2000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174957C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-DSPE (MW 2000) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 2000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174957B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-DSPE (MW 1000) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 1000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174964D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm-PEG-DSPE (MW 3400) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 3400) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-W1123922E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG-DSPE (MW 5000) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 5000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-W1123922B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG-DSPE (MW 1000) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 1000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-W800676
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-N-bis(PEG4-acid) is a branched click chemistry reagent. The DBCO group enables copper-free Click Chemistry reactions. carboxylic acid groups allows for reactions with primary amine groups using activators such as EDC or HATU to form a stable amide bond.
|
-
- HY-174957E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-DSPE (MW 5000) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 5000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174964B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm-PEG-DSPE (MW 1000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 1000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-W1123922
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG-DSPE (MW 400) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 400) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174957D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG-DSPE (MW 3400) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 3400) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-W010516R
-
|
2-Methylpentanoic acid (Standard)
|
Reference Standards
Endogenous Metabolite
|
Metabolic Disease
|
|
2-Methylvaleric acid (Standard) is the analytical standard of 2-Methylvaleric acid. This product is intended for research and analytical applications. 2-Methylvaleric acid is a branched short-chain fatty acid (SCFA) produced by the metabolism of branched-chain amino acids by gut microbes. 2-Methylvaleric acid can be used as a potential biomarker for metabolic diseases such as type 2 diabetes, and its content is significantly reduced in the feces of diabetic mice. 2-Methylvaleric acid may regulate host energy metabolism and inflammatory response through G protein-coupled receptors (GPCRs) or histone deacetylase (HDAC) inhibition. 2-Methylvaleric acid can be used to study gut microbe-host interactions and metabolic diseases as a fecal biomarker[1][2].
|
-
- HY-148242
-
BAY-069
2 Publications Verification
|
Fluorescent Dye
|
Cancer
|
|
BAY-069 is a potent branched-chain amino acid transaminases 1 (BCAT1) and BCAT2 inhibitor with IC50 values of 31 nM and 153 nM, respectively. BAY-069 also can be used as a chemical probe. BAY-069 can be used tor research anticancer .
|
-
- HY-E70286
-
|
MGAT4B
|
Biochemical Assay Reagents
|
Cancer
|
|
N-Acetylglucosaminyltransferase V (MGAT4B) is the enzyme that catalyzes the formation of the β1,6-GlcNAc branch of N-glycans in the Golgi apparatus using UDP-GlcNAc as the donor substrate. N-Acetylglucosaminyltransferase V is involved in cancer malignancy and autoimmune disease etiology .
|
-
- HY-16565
-
|
|
Biochemical Assay Reagents
Drug Intermediate
Parasite
|
Infection
|
|
10-Deacetylbaccatin-III is an intermediate in the preparation process of paclitaxel. 10-Deacetylbaccatin III can be isolated from the dried needles and small branches of the European yew tree (Taxus baccata). 10-Deacetylbaccatin III exhibits antileishmanial activity .
|
-
- HY-W401062
-
|
1,2-Epoxytridecane
|
Biochemical Assay Reagents
|
Others
|
|
2-Undecyloxirane (1,2-Epoxytridecane) is a chemical reagent featuring an epoxy group on a C11 chain. The epoxy group undergoes ring opening in the presence of nucleophiles to form a branched structure containing a secondary alcohol. Compounds such as this may be used as intermediates in building lipids for use in lipid nanoparticles.
|
-
- HY-155156
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
PF-07238025 is a BCKDC kinase (BDK) inhibitor (EC50=19 nM). PF-07238025 stabilizes the interaction between BDK and BCKDH core subunit E2 and prevents phosphorylation of E1. While BDK mediates branched-chain ketoacid dehydrogenase (BCKDH) phosphorylation, and inhibition of BCKDH is involved in controlling the rate-limiting step of branched-chain amino acid (BCAA) degradation. Impaired BCAA catabolism has been associated with several diseases, particularly cardiometabolic diseases, including heart failure (HF), type 2 diabetes mellitus (T2DM), non-alcoholic fatty liver disease (NAFLD), and obesity. PF-07238025 improved cardiometabolic endpoints and improves glucose tolerance in mice .
|
-
- HY-155157
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
PF-07247685 is a BCKDC kinase (BDK) inhibitor (EC50=2.2 nM). PF-07247685 stabilizes the interaction between BDK and BCKDH core subunit E2 and prevents phosphorylation of E1. While BDK mediates branched-chain ketoacid dehydrogenase (BCKDH) phosphorylation, and inhibition of BCKDH is involved in controlling the rate-limiting step of branched-chain amino acid (BCAA) degradation. Impaired BCAA catabolism has been associated with several diseases, particularly cardiometabolic diseases, including heart failure (HF), type 2 diabetes mellitus (T2DM), non-alcoholic fatty liver disease (NAFLD), and obesity. PF-07247685 improved cardiometabolic endpoints and improves glucose tolerance in mice .
|
-
- HY-122950
-
|
|
Fungal
|
Infection
|
|
Harzianic acid, a tetramic acid derivative, with activity of antimicrobial, antibiofilm formation and biofilm disaggregation. Harzianic acid interferes with biofilm formation by limiting bacterial iron availability. Harzianic acid is also a selective inhibitor of Acetohydroxyacid synthase (AHAS), the first enzyme in the branched-chain amino acid biosynthetic pathway. Harzianic acid can used for herbicide and fungicide .
|
-
- HY-148242A
-
|
|
Fluorescent Dye
|
Cancer
|
|
BAY-252 is a potent branched-chain amino acid transaminases 1 (BCAT1) and BCAT2 inhibitor with IC50s of 2 μM and 2 μM, respectively. BAY-069 also can be used as a chemical probe. BAY-069 can be used for the research of cancer .
|
-
- HY-131503S
-
|
13-MTD-d6; 13-Methylmyristic acid-d6
|
Isotope-Labeled Compounds
Apoptosis
|
Cancer
|
|
13-Methyltetradecanoic acid-d6 is a deuterated labeled 13-Methyltetradecanoic acid . 13-Methyltetradecanoic acid (13-MTD), a saturated branched-chain fatty acid with potent anticancer effects. 13-Methyltetradecanoic acid induces apoptosis in many types of human cancer cells .
|
-
- HY-N3612
-
|
(+)-Communic acid
|
Bacterial
Akt
MMP
|
Infection
Inflammation/Immunology
|
|
Communic acid ((+)-Communic acid) is a natural compound isolated from the branches of Platycladus orientalis. Communic acid displays minimum inhibitory concentration of 31 μM and IC50 of 15 μM against M. tuberculosis H37Ra.Communic acid exhibits protective effects against UVB-induced skin aging .
|
-
- HY-141669
-
|
|
Aminotransferases (Transaminases)
|
Metabolic Disease
|
|
BCAT-IN-2 is a potent, selective and orally active inhibitor of mitochondrial branched-chain aminotransferase (BCATm), with a pIC50 of 7.3. BCAT-IN-2 shows selectivity for BCATm over BCATc (pIC50=6.6). BCAT-IN-2 can be used for the research of obesity and dislipidema .
|
-
- HY-B1122
-
|
(S)-Cycloserine; (S)-4-Amino-3-isoxazolidone
|
GABA Receptor
HIV
|
Neurological Disease
Cancer
|
|
L-Cycloserine ((S)-4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase (GABA-t) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains .
|
-
- HY-B1845
-
|
|
Herbicide
|
Others
|
|
Florasulam is a targeted post-emergent herbicide belonging to the triazolopyrimidine sulfonanilide class, which functions by inhibiting acetolactate synthase (ALS) in plants. Located in the chloroplasts, ALS plays a crucial role in the biosynthesis of branched-chain amino acids. When Florasulam inhibits ALS, it disrupts plant cell division, reduces growth, and ultimately leads to plant death.
|
-
- HY-W654264
-
|
|
Endogenous Metabolite
Integrin
|
Cardiovascular Disease
|
|
2-Methylbutyrylcarnitine (chloride) is a gut microbial metabolite which binds to integrin α2β1 in platelets, potentiating cytosolic phospholipase A2 (cPLA2) activation and platelet hyperresponsiveness. 2-Methylbutyrylcarnitine (chloride) enhances platelet hyperreactivity and thrombus formation in mice. 2-Methylbutyrylcarnitine (chloride) is a branched-chain acylcarnitine .
|
-
- HY-W422402R
-
|
|
Reference Standards
Acetolactate Synthase (ALS)
|
Others
|
|
Foramsulfuron (Standard) is the analytical standard of Foramsulfuron. This product is intended for research and analytical applications. Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids .
|
-
- HY-171897
-
|
|
Liposome
|
Inflammation/Immunology
Cancer
|
|
E10i-494 is an ionizable cationic branched endosomal disruptor (BEND) lipid. E10i-494 can be used to generate lipid nanoparticles (LNPs) for mRNA delivery in vitro. E10i-494 can enhance transfection efficiency .
|
-
- HY-136403
-
|
|
Phytohormone
|
Others
|
|
TIS108 is a triazole-type strigolactone biosynthesis inhibitor. TIS108 inhibits Arabidopsis embryogenesis and root hair growth, and promotes shoot branching. TIS108 can also increase the gibberellin content in Gastrodia elata. TIS108 can be used in the research of plant growth and development as well as plant responses to the environment .
|
-
- HY-113511B
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Glycogen, from rabbit liver, ≥85% is glycogen extracted from rabbit liver. Glycogen, from rabbit liver, ≥85% is a branched polysaccharide condensed from glucose and serves as a storage form of glucose in the body. Glycogen, from rabbit liver, ≥85% plays an important role in physiological processes such as maintaining blood sugar and providing energy .
|
-
- HY-W721637
-
|
|
Isotope-Labeled Compounds
Acetolactate Synthase (ALS)
|
Others
|
|
Foramsulfuron-d6-1 is the deuterium labeled Foramsulfuron (HY-W422402). Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids .
|
-
- HY-W110242A
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
(S)-CPP sodium serves as an inhibitor of the branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, the inhibition of BDK by (S)-CPP (with an IC50 of 6.3 μM) results in the activation of the complex and a notable decrease in plasma levels of leucine/isoleucine and valine in wild-type mice.
|
-
- HY-W190958
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-NH-Tri-(carbonylethoxymethyl)-methane is a branched PEG linker with a Boc-protected amino and three terminal carboxilic acid groups. The Boc group can be deprotected under mild acidic conditions to form the free amine. The terminal carboxylic acid groups can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
|
-
- HY-113037C
-
|
Farnesyl diphosphate ammonium
|
TRP Channel
Endogenous Metabolite
|
Neurological Disease
|
|
Farnesyl pyrophosphate ammonium salt, a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. Farnesyl pyrophosphate ammonium salt is a TRPM2 (TRP Channel) agonist, and activates TRPM2 opening for ion influx. Farnesyl pyrophosphate ammonium salt is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis .
|
-
- HY-116044
-
|
|
Aminotransferases (Transaminases)
|
Neurological Disease
|
|
BCATc Inhibitor 2 is a selective branched-chain aminotransferase (BCAT) inhibitor for research of neurodegenerative diseases. The IC50s of 0.2 μM, 0.8 μM and 3.0 μM for rat cytosolic isoenzyme rBCATc, human cytosolic isoenzyme hBCATc and rat mitochondrial isoenzyme rBCATm, respectively. BCATc, also called BCAT1, is in the cytoplasm .
|
-
- HY-E70097
-
|
|
Endogenous Metabolite
|
Others
|
|
Sialidase (α2-3-6-8-9) is a broadly specific sialidase that cuts linear and branched non-reducing terminal sialic acid residues from glycoproteins, glycopeptides, and oligosaccharides. Sialidase (α2-3-6-8-9) can be used for in vitro and in vivo polysaccharide analysis and characterization as well as complete glycoprotein remodeling .
|
-
- HY-B0869A
-
|
|
Acetolactate Synthase (ALS)
SOD
|
Metabolic Disease
|
|
Bispyribac sodium is a selective, orally active, systemic and post-emergence herbicide. Bispyribac sodium reduces SOD levels and inhibits ALS activity. Bispyribac sodium blocks the biosynthesis of branched-chain amino acids, resulting in growth retardation, chlorosis and necrosis of weeds. Bispyribac sodium exerts herbicidal activity against grass, sedge and broadleaf weeds in rice fields. Bispyribac sodium is hepatotoxic and genotoxic .
|
-
- HY-135969
-
|
|
Bacterial
|
Infection
|
|
Glycol chitosan is a chitosan derivative with ethylene glycol branches. Glycol chitosan enhances membrane permeability and leadkage in Glycine max Harosoy 63W cells. Glycol chitosan is biocompatible and biodegradable . Glycol chitosan inhibits E. coli, S. aureus and S. enteritidis growths with MIC values of 4 μg/mL, 32 μg/mL and <0.5 μg/mL, respectively .
|
-
- HY-W010513R
-
|
|
Reference Standards
Biochemical Assay Reagents
|
Others
|
|
3-Methylvaleric acid (Standard) is an analytical standard form of 3-Methylvaleric acid (HY-W010513). This product is intended for research and analytical applications. 3-Methylvaleric Acid is a branched alkanoic acid. 3-Methylvaleric Acid can be utilized by Pseudomonas citronettotis as a sole carbon source for its growth. 3-Methylvaleric Acid derivatives exhibit anti-hyperalgesic and anticonvulsant activities .
|
-
- HY-114855
-
|
|
Bcl-2 Family
|
Metabolic Disease
|
|
BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC) . BT2 (compound 4) is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM .
|
-
- HY-139104
-
|
|
DNA/RNA Synthesis
Apoptosis
|
Cancer
|
|
Thailanstatin D, an analogue of Thailanstatin A, is able to inhibit AR-V7 gene splicing by interfering the interaction between U2AF65 and SAP155 and preventing them from binding to polypyrimidine tract located between the branch point and the 3' splice site. Thailanstatin D exhibits a potent tumor inhibitory effect on human CRPC xenografts leading to cell apoptosis .
|
-
- HY-B1845R
-
|
|
Endogenous Metabolite
Reference Standards
|
Others
|
|
Florasulam (Standard) is the analytical standard of Florasulam. This product is intended for research and analytical applications. Florasulam is a targeted post-emergent herbicide belonging to the triazolopyrimidine sulfonanilide class, which functions by inhibiting acetolactate synthase (ALS) in plants. Located in the chloroplasts, ALS plays a crucial role in the biosynthesis of branched-chain amino acids. When Florasulam inhibits ALS, it disrupts plant cell division, reduces growth, and ultimately leads to plant death.
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-
- HY-P2124R
-
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Reference Standards
Antibiotic
Bacterial
|
Infection
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|
L-Isoleucine (Standard) is the analytical standard of L-Isoleucine. This product is intended for research and analytical applications. L-Isoleucine is an orally active branched chain amino acid, which is the L-enantiomer of isoleucine. L-Isoleucine has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. L-Isoleucine regulates the inflammatory response to protect against pathogens in vivo and in vitro .
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-
- HY-W014206
-
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Biochemical Assay Reagents
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Others
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Isopentyl octanoate is a class of esters formed by the esterification of branched-chain isoamyl alcohol, also known as isoamyl alcohol, with octanoylate. The compound has a fruity smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It can also be used as a fragrance ingredient in personal care products, and as a solvent or plasticizer in various industrial applications. In addition, Isopentyl octanoate can be used as a starting material for the synthesis of other organic compounds.
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- HY-N1720
-
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Others
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Others
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2α,3α,24-Trihydroxyolean-12-en-28-oic acid (compound 5) is a terpenoid that is isolated from the branches and leaves of Pyrus pashia. 2α,3α,24-Trihydroxyolean-12-en-28-oic acid shows cytotoxic activity .
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-
- HY-B1122R
-
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(S)-Cycloserine (Standard); (S)-4-Amino-3-isoxazolidone (Standard)
|
Reference Standards
GABA Receptor
HIV
|
Neurological Disease
Cancer
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L-Cycloserine (Standard) is the analytical standard of L-Cycloserine. This product is intended for research and analytical applications. L-Cycloserine ((S)-4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase (GABA-t) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains[1][2][3][4].
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-
- HY-W1005647
-
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Biochemical Assay Reagents
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Others
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(rac)-Isoleucine is the racemic form of Isoleucine. Isoleucine is a mixture of the diastereomers L-isoleucine, L-alloisoleucine, D-isoleucine, and D-alloisoleucine. L-isoleucine is a branched-chain amino acid that acts as a nitrogen donor, and has roles in glucose consumption, fatty acid metabolism, as well as immune function. L-Alloisoleucine is generated by transamination of L-isoleucine. D-Isoleucine and D-alloisoleucine are enantiomers of L-isoleucine and L-alloisoleucine, respectively .
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-
- HY-W015667
-
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Ethyl 2-methylvalerate
|
Biochemical Assay Reagents
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Others
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|
Ethyl 2-methylpentanoate is a class of esters consisting of branched-chain isovaleric acid esterified with ethanol. The compound has a fruity, pungent smell and is commonly used as a flavoring in foods such as baked goods, dairy products and beverages. It can also be used as a fragrance ingredient in personal care products, and as a solvent or plasticizer in various industrial applications. In addition, Ethyl 2-methylpentanoate can be used as a starting material for the synthesis of other organic compounds.
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- HY-158614
-
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16:0-12-PAHSA-18:1-TG; TG(16:0/12-PAHSA/18:1)
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Endogenous Metabolite
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Others
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1-Palmitoyl-2-12-PAHSA-3-oleoyl-sn-glycerol (16:0-12-PAHSA-18:1-TG) is a FAHFAs-containing triglyceride that can be synthesized from isotope-labeled FAHFAs, whose decomposition can regulate intracellular FAHFAs levels, and is the major reservoir of FAHFAs in cells and tissues, revealing the activity of a new branch of TG and FAHFAs metabolism.
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-
- HY-113037
-
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(E/Z)-Farnesyl diphosphate
|
TRP Channel
Endogenous Metabolite
|
Neurological Disease
|
|
(E/Z)-Farnesyl pyrophosphate ((E/Z)-Farnesyl diphosphate), a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. (E/Z)-Farnesyl pyrophosphate is a TRPM2 (TRP Channel) agonist, activates TRPM2 opening for ion influx. (E/Z)-Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis .
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- HY-128692
-
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Fluorescent Dye
|
Neurological Disease
|
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Lucifer Yellow CH dilithium salt is a high-intensity fluorescent probe containing free hydrazyl groups. Lucifer Yellow CH can react with fatty aldehydes at room temperature. Lucifer Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Lucifer yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively .
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-
- HY-171984
-
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Liposome
|
Infection
Inflammation/Immunology
Cancer
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|
514O6,10 is an ionizable lipidoid containing a branched-tail. 514O6,10 can be used to synthesize lipid nanoparticles (LNPs) for delivering mRNA to natural killer and dendritic cells within the lung. 514O6,10 can be used for the RNA therapies for lung diseases associated with immune cell dysregulation, including cancer, viral infections, and autoimmune disorders research .
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-
- HY-W127715
-
|
|
Fluorescent Dye
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Others
|
|
Lucifer Yellow CH dipotassium is a high-intensity fluorescent probe containing free hydrazyl groups. Lucifer Yellow CH can react with fatty aldehydes at room temperature. Lucifer Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Lucifer yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively .
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-
- HY-W800708
-
|
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Biochemical Assay Reagents
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Others
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N-(TCO)-N-bis(PEG4-acid) is a branched click chemistry reagent with a terminal TCO group and two terminal carboxylic acids. This reagent can react with tetrazine-containing molecule to form a stable covalent bond . The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acids can react with primary amino groups in the presence of activators (e.g. EDC, HATU ).
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-
- HY-P2988A
-
|
|
Influenza Virus
|
Metabolic Disease
|
|
α2-3,6 Neuraminidase, Bifidobacterium infantis is a highly specific exoglycosidase that catalyzes the hydrolysis of non-reducing terminal α2-3 and α2-6 unbranched sialic acid residues from complex carbohydrates and glycoproteins. α2-3,6 Neuraminidase does not exhibit activity on α2-8 or branched sialic acids .
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-
- HY-B1876
-
|
|
Acetolactate Synthase (ALS)
Photosystem II
Fungal
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Others
|
|
Nicosulfuron is efficient, harmless, antifungal and selective herbicide belonging to the sulfonylurea family. Nicosulfuron is also a photosynthetic system inhibitor and inhibits acetolactate synthase (ALS) enzyme activity. Nicosulfuron degradation by Plectosphaerella cucumerina AR1 is glucose concentration dependent in planktonic lifestyle. Nicosulfuron enhances the glycolysis pathway and tricarboxylic acid cycle to improve the adaptability of sweet maize. Nicosulfuron reduces the synthesis of branched-chain amino acids (BCAAs), which is proming for maize cultivation .
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-
- HY-147206C
-
|
|
Fluorescent Dye
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Others
|
|
Biotin-PEG-Alk (MW 3400) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 3400) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-147206A
-
|
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Fluorescent Dye
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Others
|
|
Biotin-PEG-Alk (MW 1000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 1000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-N15007
-
|
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Others
|
Others
|
|
6-Ethoxyethyl-5-hydroxy-2,7-dime-thoxy-1,4-naphtoquinone is a naphthoquinone compound that causes branch wilt in larch and inhibits seed germination and growth in lettuce. 6-Ethoxyethyl-5-hydroxy-2,7-dime-thoxy-1,4-naphtoquinone completely inhibits hypocotyl and root growth at 100 ppm and more than 95% at 50 ppm .
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-
- HY-147206E
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG-Alk (MW 10000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 10000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147206B
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG-Alk (MW 2000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 2000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147206F
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG-Alk (MW 20000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 20000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-B0869AR
-
|
|
Reference Standards
Acetolactate Synthase (ALS)
SOD
|
Metabolic Disease
|
|
Bispyribac (sodium) (Standard) is the analytical standard of Bispyribac sodium (HY-B0869A). This product is intended for research and analytical applications. Bispyribac sodium is a selective, orally active, systemic and post-emergence herbicide. Bispyribac sodium reduces SOD levels and inhibits ALS activity. Bispyribac sodium blocks the biosynthesis of branched-chain amino acids, resulting in growth retardation, chlorosis and necrosis of weeds. Bispyribac sodium exerts herbicidal activity against grass, sedge and broadleaf weeds in rice fields. Bispyribac sodium is hepatotoxic and genotoxic .
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-
- HY-113058R
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
3-Hydroxyoctanoic acid (Standard) is the analytical standard of 3-Hydroxyoctanoic acid (HY-113058). 3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet.
|
-
- HY-120883
-
|
|
Others
|
Infection
|
|
Rhizopodin is a new cytostatic compound isolated from the culture fluid of the slime mold Myxococcus stipitatus. Rhizopodin inhibits the growth of various animal cell cultures without killing the cells, with an ID50 value of 12 to 30 ng/ml, depending on the cell line. In particular, fibroblast-like cells show typical morphological changes, with cells becoming larger and forming long branched reticular extensions within hours, and these morphological changes are irreversible. Rhizopodin inhibits bleb formation in K-562 cells, possibly through interaction with protein phosphorylation.
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-
- HY-113058
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.
|
-
- HY-121779
-
|
2,4'-DDE; 2,4-Dichlorodiphenyldichloroethylene; 2,4'-DDE; o,p'-Dichlorodiphenyldichloroethylene
|
Insecticide
|
Endocrinology
|
|
o,p'-DDE (2,4-Dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT. It accumulates in smallmouth buffalo, channel catfish, and largemouth bass, and in sediments from DDT manufacturing plants around the Huntsville Spring Branch-Indian Creek tributary system, where it is considered a persistent organic pollutant (POP). o,p'-DDE inhibits estrogen binding to the rainbow trout estrogen receptor (rtER) with an IC50 value of 3.2 μM. It induces concentration-dependent estradiol secretion in co-cultures of granulosa and theca cells isolated from porcine follicles. In ovo exposure to o,p'-DDE increases follicular degeneration and reduces testis size in Japanese medaka (O. latipes).
|
-
- HY-N15936
-
|
|
Toll-like Receptor (TLR)
Interleukin Related
|
Inflammation/Immunology
|
|
a15:0-i15:0 PE is a diacyl phosphatidylethanolamine with two branched chains. a15:0-i15:0 PE is a non-canonical TLR2-TLR1 heterodimer agonist and has immunogenic activity. a15:0-i15:0 PE activates T cells and DC signaling and shows anti-inflammatory activity. a15:0-i15:0 PE induces TNFα and IL-6 production. a15:0-i15:0 PE is a the major component (approximately 50%) of A. muciniphila’s lipid membrane .
|
-
- HY-137566
-
|
|
Mitochondrial Metabolism
|
Cancer
|
|
Cucumarioside H is a novel triterpene glycoside isolated from the Far Eastern sea cucumber Eupentacta fraudatrix, including H2, H3 and H4. These glycosides have a branched pentasyl structure with a rare 3-O-methyl-D-xylose as the terminal monosaccharide. H2 contains 23,24,25,26,27-pentanolone sterols and has an 18(16)-lactone, which is not common in sea cucumbers. The glycoside portion of H3 contains an extremely rare ethoxyl radical at the 25 position, which may be an artifact formed during the long ethanol extraction process. Studies have shown that H1-3 are cytotoxic to mouse spleen lymphocytes, hemolytic to mouse erythrocytes, and cytotoxic to Ehrlich carcinoma cells. The presence of a 25-hydroxyl group in the glycoside portion significantly reduces these activities.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-128692
-
|
|
Fluorescent Dyes/Probes
|
|
Lucifer Yellow CH dilithium salt is a high-intensity fluorescent probe containing free hydrazyl groups. Lucifer Yellow CH can react with fatty aldehydes at room temperature. Lucifer Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Lucifer yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively .
|
-
- HY-W127715
-
|
|
Fluorescent Dyes/Probes
|
|
Lucifer Yellow CH dipotassium is a high-intensity fluorescent probe containing free hydrazyl groups. Lucifer Yellow CH can react with fatty aldehydes at room temperature. Lucifer Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Lucifer yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively .
|
| Cat. No. |
Product Name |
Type |
-
- HY-W762023
-
-
- HY-W127484
-
|
14-Methylpentadecanoic acid
|
Drug Delivery
|
|
14-Methylpentadecanoic acid is a branched-chain fatty acid that has been found in soil bacteria. 1,2
|
-
- HY-151507
-
|
|
Drug Delivery
|
|
306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .
|
-
- HY-W250110I
-
|
PEI (branched) (MW 10000)
|
Drug Delivery
|
|
Polyethylenimine (branched) (MW 10000) (PEI (branched) (MW 10000)) is a cationic polymer widely used as a nonviral nucleotide delivery reagent .
|
-
- HY-134422
-
|
Isobutyryl CoA lithium
|
Enzyme Substrates
|
|
Isobutyryl coenzyme A (Isobutyryl CoA) lithium is A coenzyme A involved in the metabolic pathway of fatty acids. Isobutyryl coenzyme A lithium is made by combining isobutyric acid (short chain branched fatty acid) with coenzyme A.
|
-
- HY-131960A
-
|
Polysucrose 70
|
Carbohydrates
|
|
Sucrose-epichlorohydrin copolymer 70 (Polysucrose 70) is a branched polysaccharide polymer with a high molecular weight. Sucrose-epichlorohydrin copolymer 70 is formed by the copolymerization of sucrose and epichlorohydrin, which can be used for cell separation .
|
-
- HY-N7842
-
|
17-Methylstearic acid; 17-Methyloctadecanoic acid
|
Biochemical Assay Reagents
|
|
17-Methylstearic acid is a methyl-branched fatty acid that has been found in mouse meibomian glands, C. cornucopioides mushrooms, and Phytobacter species. It is also found in the aerial parts of C. ladanifer, where its concentration varies seasonally.
|
-
- HY-E70140
-
|
EC 2.4.1; A4GNT
|
Enzyme Substrates
|
|
α-1,4-N-Acetylglucosaminyltransferase 4 (EC 2.4.1, A4GNT) catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans and suppresses H. pylori growth .
|
-
- HY-W1123922H
-
|
|
Drug Delivery
|
|
4-Arm-PEG-DSPE (MW 10000) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 10000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174964H
-
|
|
Drug Delivery
|
|
8-Arm-PEG-DSPE (MW 10000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 10000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174964E
-
|
|
Drug Delivery
|
|
8-Arm-PEG-DSPE (MW 5000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 5000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174964C
-
|
|
Drug Delivery
|
|
8-Arm-PEG-DSPE (MW 2000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 2000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-W1123922A
-
|
|
Drug Delivery
|
|
4-Arm-PEG-DSPE (MW 600) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 600) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174964
-
|
|
Drug Delivery
|
|
8-Arm-PEG-DSPE (MW 400) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 1000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174957
-
|
|
Drug Delivery
|
|
6-Arm-PEG-DSPE (MW 400) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 400) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174957A
-
|
|
Drug Delivery
|
|
6-Arm-PEG-DSPE (MW 600) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 600) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174964A
-
|
|
Drug Delivery
|
|
8-Arm-PEG-DSPE (MW 600) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 600) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-W1123922D
-
|
|
Drug Delivery
|
|
4-Arm-PEG-DSPE (MW 3400) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 3400) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174957H
-
|
|
Drug Delivery
|
|
6-Arm-PEG-DSPE (MW 10000) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 10000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-W1123922C
-
|
|
Drug Delivery
|
|
4-Arm-PEG-DSPE (MW 2000) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 2000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174957C
-
|
|
Drug Delivery
|
|
6-Arm-PEG-DSPE (MW 2000) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 2000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174957B
-
|
|
Drug Delivery
|
|
6-Arm-PEG-DSPE (MW 1000) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 1000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174964D
-
|
|
Drug Delivery
|
|
8-Arm-PEG-DSPE (MW 3400) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 3400) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-W1123922E
-
|
|
Drug Delivery
|
|
4-Arm-PEG-DSPE (MW 5000) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 5000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-W1123922B
-
|
|
Drug Delivery
|
|
4-Arm-PEG-DSPE (MW 1000) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 1000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174957E
-
|
|
Drug Delivery
|
|
6-Arm-PEG-DSPE (MW 5000) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 5000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174964B
-
|
|
Drug Delivery
|
|
8-Arm-PEG-DSPE (MW 1000) is a PEG cross-linking reagent that links eight PEG branches to one DSPE phospholipid. 8-Arm-PEG-DSPE (MW 1000) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-W1123922
-
|
|
Drug Delivery
|
|
4-Arm-PEG-DSPE (MW 400) is a PEG cross-linking reagent that links four PEG branches to one DSPE phospholipid. 4-Arm-PEG-DSPE (MW 400) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-174957D
-
|
|
Drug Delivery
|
|
6-Arm-PEG-DSPE (MW 3400) is a PEG cross-linking reagent that links six PEG branches to one DSPE phospholipid. 6-Arm-PEG-DSPE (MW 3400) can be used for drug delivery, gene transfection, and vaccine delivery .
|
-
- HY-E70142
-
|
EC:2.4.1.102; GCNT1
|
Enzyme Substrates
|
|
Glucosaminyl (N-acetyl) Transferase 1 ( EC:2.4.1.102, GCNT1) is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch and play an important role in cancer .
|
-
- HY-113511B
-
|
|
Microbial Culture
|
|
Glycogen, from rabbit liver, ≥85% is glycogen extracted from rabbit liver. Glycogen, from rabbit liver, ≥85% is a branched polysaccharide condensed from glucose and serves as a storage form of glucose in the body. Glycogen, from rabbit liver, ≥85% plays an important role in physiological processes such as maintaining blood sugar and providing energy .
|
-
- HY-135969
-
|
|
Drug Delivery
|
|
Glycol chitosan is a chitosan derivative with ethylene glycol branches. Glycol chitosan enhances membrane permeability and leadkage in Glycine max Harosoy 63W cells. Glycol chitosan is biocompatible and biodegradable . Glycol chitosan inhibits E. coli, S. aureus and S. enteritidis growths with MIC values of 4 μg/mL, 32 μg/mL and <0.5 μg/mL, respectively .
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- HY-W014206
-
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Biochemical Assay Reagents
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Isopentyl octanoate is a class of esters formed by the esterification of branched-chain isoamyl alcohol, also known as isoamyl alcohol, with octanoylate. The compound has a fruity smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It can also be used as a fragrance ingredient in personal care products, and as a solvent or plasticizer in various industrial applications. In addition, Isopentyl octanoate can be used as a starting material for the synthesis of other organic compounds.
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- HY-W015667
-
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Ethyl 2-methylvalerate
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Biochemical Assay Reagents
|
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Ethyl 2-methylpentanoate is a class of esters consisting of branched-chain isovaleric acid esterified with ethanol. The compound has a fruity, pungent smell and is commonly used as a flavoring in foods such as baked goods, dairy products and beverages. It can also be used as a fragrance ingredient in personal care products, and as a solvent or plasticizer in various industrial applications. In addition, Ethyl 2-methylpentanoate can be used as a starting material for the synthesis of other organic compounds.
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- HY-113058
-
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Biochemical Assay Reagents
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3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.
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| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-112173
-
-
- HY-P3743
-
|
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Src
Peptides
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Others
|
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p60c-src Substrate is an efficient and specific substrate for p60c-src protein tyrosine kinase (PTK). p60c-src Substrate can be used to synthesize chimeric branched peptides .
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-
- HY-P10007
-
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Z-GPFL-CHO
|
Proteasome
|
Cancer
|
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Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde that acts as a highly selective and potent proteasomal inhibitor (Ki = 1.5 µM for branched chain amino acid preferring, 2.3 µM for small neutral amino acid preferring, and 40.5 µM for chymotrypsin-like activities; IC50 = 3.1 µM for peptidyl-glutamyl peptide hydrolyzing activity) .
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- HY-P2124R
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Reference Standards
Antibiotic
Bacterial
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Infection
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L-Isoleucine (Standard) is the analytical standard of L-Isoleucine. This product is intended for research and analytical applications. L-Isoleucine is an orally active branched chain amino acid, which is the L-enantiomer of isoleucine. L-Isoleucine has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. L-Isoleucine regulates the inflammatory response to protect against pathogens in vivo and in vitro .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
- HY-W654264
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-
- HY-113037C
-
-
- HY-139104
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-
- HY-N1720
-
-
- HY-B1122R
-
-
- HY-113037
-
-
- HY-120883
-
|
|
Structural Classification
Microorganisms
Macrolide Antibiotics
Antibiotics
Source classification
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Others
|
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Rhizopodin is a new cytostatic compound isolated from the culture fluid of the slime mold Myxococcus stipitatus. Rhizopodin inhibits the growth of various animal cell cultures without killing the cells, with an ID50 value of 12 to 30 ng/ml, depending on the cell line. In particular, fibroblast-like cells show typical morphological changes, with cells becoming larger and forming long branched reticular extensions within hours, and these morphological changes are irreversible. Rhizopodin inhibits bleb formation in K-562 cells, possibly through interaction with protein phosphorylation.
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- HY-113058
-
|
|
Microorganisms
Source classification
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Endogenous Metabolite
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|
3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.
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-
- HY-N15936
-
|
|
Structural Classification
Lipid
|
Toll-like Receptor (TLR)
Interleukin Related
|
|
a15:0-i15:0 PE is a diacyl phosphatidylethanolamine with two branched chains. a15:0-i15:0 PE is a non-canonical TLR2-TLR1 heterodimer agonist and has immunogenic activity. a15:0-i15:0 PE activates T cells and DC signaling and shows anti-inflammatory activity. a15:0-i15:0 PE induces TNFα and IL-6 production. a15:0-i15:0 PE is a the major component (approximately 50%) of A. muciniphila’s lipid membrane .
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-
- HY-137566
-
|
|
Triterpenes
Structural Classification
Animals
Terpenoids
Source classification
|
Mitochondrial Metabolism
|
|
Cucumarioside H is a novel triterpene glycoside isolated from the Far Eastern sea cucumber Eupentacta fraudatrix, including H2, H3 and H4. These glycosides have a branched pentasyl structure with a rare 3-O-methyl-D-xylose as the terminal monosaccharide. H2 contains 23,24,25,26,27-pentanolone sterols and has an 18(16)-lactone, which is not common in sea cucumbers. The glycoside portion of H3 contains an extremely rare ethoxyl radical at the 25 position, which may be an artifact formed during the long ethanol extraction process. Studies have shown that H1-3 are cytotoxic to mouse spleen lymphocytes, hemolytic to mouse erythrocytes, and cytotoxic to Ehrlich carcinoma cells. The presence of a 25-hydroxyl group in the glycoside portion significantly reduces these activities.
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-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-N0486S
-
|
|
|
L-Leucine-d10 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
|
-
-
- HY-N0486S12
-
|
|
|
L-Leucine-d2 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
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-
-
- HY-N0486S9
-
1 Publications Verification
|
|
L-Leucine-d3 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
|
-
-
- HY-N0486S2
-
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|
|
Leucine- 13C6 is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
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-
-
- HY-N0486S1
-
|
|
|
L-Leucine- 13C is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
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-
-
- HY-N0486S3
-
|
|
|
L-Leucine- 15N is the 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
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-
-
- HY-N0486S13
-
|
|
|
L-Leucine- 15N,d10 is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
|
-
-
- HY-N0486S11
-
|
|
|
L-Leucine-d is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
|
-
-
- HY-N0486S4
-
|
|
|
L-Leucine-d7 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
|
-
-
- HY-N0486S10
-
|
|
|
L-Leucine- 18O2 is the 18O-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
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-
-
- HY-N0486S5
-
|
|
|
L-Leucine-2- 13C is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
|
-
-
- HY-I1060S
-
|
|
|
L-Alloisoleucine-d10 is the deuterium labeled L-Alloisoleucine. L-Alloisoleucine is a branched chain amino acid and is a stereo-isomer of L-isoleucine. L-Alloisoleucine is a common constituent of human plasma (albeit at low levels).
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-
-
- HY-N0486S8
-
|
|
|
L-Leucine- 13C6, 15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
|
-
-
- HY-N0486S6
-
|
|
|
L-Leucine-2- 13C, 15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
|
-
-
- HY-N0486S7
-
|
|
|
L-Leucine-1- 13C, 15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
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-
-
- HY-W721687
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|
|
|
3,3-Dimethylbutyric acid-d9 (tert-Butylacetic acid-d9) is a deuterated derivative of 3,3-Dimethylbutyric acid, which is a short-chain branched carboxylic acid and can be used in organic synthesis .
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-
-
- HY-131503S
-
|
|
|
13-Methyltetradecanoic acid-d6 is a deuterated labeled 13-Methyltetradecanoic acid . 13-Methyltetradecanoic acid (13-MTD), a saturated branched-chain fatty acid with potent anticancer effects. 13-Methyltetradecanoic acid induces apoptosis in many types of human cancer cells .
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-
-
- HY-W721637
-
|
|
|
Foramsulfuron-d6-1 is the deuterium labeled Foramsulfuron (HY-W422402). Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids .
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-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W800717
-
|
|
|
Azide
|
|
Tetra-(amido-PEG10-azide) is a branched PEG linker with four terminal azide groups. The azide groups enable PEGylation via Click Chemistry.
|
-
- HY-W800716
-
|
|
|
Azide
|
|
Tri(Azide-PEG10-NHCO-ethyloxyethyl)amine is a branched PEG linker with three terminal azide groups. The azide groups enable PEGylation via Click Chemistry.
|
-
- HY-W800676
-
|
|
|
DBCO
|
|
DBCO-N-bis(PEG4-acid) is a branched click chemistry reagent. The DBCO group enables copper-free Click Chemistry reactions. carboxylic acid groups allows for reactions with primary amine groups using activators such as EDC or HATU to form a stable amide bond.
|
-
- HY-147206C
-
|
|
|
Alkynes
|
|
Biotin-PEG-Alk (MW 3400) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 3400) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147206A
-
|
|
|
Alkynes
|
|
Biotin-PEG-Alk (MW 1000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 1000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147206E
-
|
|
|
Alkynes
|
|
Biotin-PEG-Alk (MW 10000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 10000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147206B
-
|
|
|
Alkynes
|
|
Biotin-PEG-Alk (MW 2000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 2000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-147206F
-
|
|
|
Alkynes
|
|
Biotin-PEG-Alk (MW 20000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 20000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-158861
-
|
G1-nPr-C14E
|
|
Cationic Lipids
|
|
C3-K2-E14 is a multi-ionizable amino-lipid featuring a central tertiary amine with two identical branches and an n-propyl group. Each branch features a propanamide linking to a branched amine, each with two C14 arms and a hydroxyl. Ionizable lipids such as this may be applied in the development of lipid nanoparticles for drug discovery.
|
-
- HY-N0486
-
|
Leucine
|
|
Others
|
|
L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
|
-
- HY-151507
-
|
|
|
Cationic Lipids
|
|
306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .
|
-
- HY-N6664
-
|
Arabic gum
|
|
Emulsifiers
Suspending Agents
|
|
Gum Arabic (Arabic gum) is a branched-chain, complex polysaccharide derive from A. Senegal. Gum Arabic is an anti-oxidant, and can protect against experimental hepatic-, renal- and cardiac toxicities. Gum Arabic also can be used in immunohistochemistry .
|
-
- HY-135969
-
|
|
|
Polymers
|
|
Glycol chitosan is a chitosan derivative with ethylene glycol branches. Glycol chitosan enhances membrane permeability and leadkage in Glycine max Harosoy 63W cells. Glycol chitosan is biocompatible and biodegradable . Glycol chitosan inhibits E. coli, S. aureus and S. enteritidis growths with MIC values of 4 μg/mL, 32 μg/mL and <0.5 μg/mL, respectively .
|
-
- HY-160569
-
|
|
|
Cationic Lipids
|
|
C14-SPM is a polyamine branched-chain lipidoid that can be used for the delivery of siRNA .
|
-
- HY-W440820
-
|
|
|
Cationic Lipids
|
|
Bis(bis(2-carboxyethyl)aminopropyl)methylamine is a symmetrical branched linker featuring three tertiary amines and four carboxylic acids. Each carboxylic acid is open to forming esters or amides. It can be used in developing lipid nanoparticles.
|
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