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  3. Boc-NH-Tri-(carbonylethoxymethyl)-methane

Boc-NH-Tri-(carbonylethoxymethyl)-methane 

Cat. No.: HY-W190958 Purity: 98.38%
Handling Instructions Technical Support

Boc-NH-Tri-(carbonylethoxymethyl)-methane is a branched PEG linker with a Boc-protected amino and three terminal carboxilic acid groups. The Boc group can be deprotected under mild acidic conditions to form the free amine. The terminal carboxylic acid groups can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

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Boc-NH-Tri-(carbonylethoxymethyl)-methane

Boc-NH-Tri-(carbonylethoxymethyl)-methane Chemical Structure

CAS No. : 220431-61-8

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Description

Boc-NH-Tri-(carbonylethoxymethyl)-methane is a branched PEG linker with a Boc-protected amino and three terminal carboxilic acid groups. The Boc group can be deprotected under mild acidic conditions to form the free amine. The terminal carboxylic acid groups can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Molecular Weight

437.44

Formula

C18H31NO11

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC(COCCC(O)=O)(COCCC(O)=O)COCCC(O)=O)OC(C)(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (228.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2860 mL 11.4301 mL 22.8603 mL
5 mM 0.4572 mL 2.2860 mL 4.5721 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2860 mL 11.4301 mL 22.8603 mL 57.1507 mL
5 mM 0.4572 mL 2.2860 mL 4.5721 mL 11.4301 mL
10 mM 0.2286 mL 1.1430 mL 2.2860 mL 5.7151 mL
15 mM 0.1524 mL 0.7620 mL 1.5240 mL 3.8100 mL
20 mM 0.1143 mL 0.5715 mL 1.1430 mL 2.8575 mL
25 mM 0.0914 mL 0.4572 mL 0.9144 mL 2.2860 mL
30 mM 0.0762 mL 0.3810 mL 0.7620 mL 1.9050 mL
40 mM 0.0572 mL 0.2858 mL 0.5715 mL 1.4288 mL
50 mM 0.0457 mL 0.2286 mL 0.4572 mL 1.1430 mL
60 mM 0.0381 mL 0.1905 mL 0.3810 mL 0.9525 mL
80 mM 0.0286 mL 0.1429 mL 0.2858 mL 0.7144 mL
100 mM 0.0229 mL 0.1143 mL 0.2286 mL 0.5715 mL
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Boc-NH-Tri-(carbonylethoxymethyl)-methane Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Boc-NH-Tri-(carbonylethoxymethyl)-methane
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HY-W190958
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