Search Result

Results for "

beta-lactamases

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Beta-lactamase (172) Angiotensin-converting Enzyme (ACE) (5) Antibiotic (115) Apoptosis (12) Autophagy (6) Bacterial (202) Bcl-2 Family (1) Biochemical Assay Reagents (1) CFTR (2) Cholinesterase (ChE) (1) Complement System (1) Drug Intermediate (3) Drug Metabolite (1) Endogenous Metabolite (5) Endothelin Receptor (1) Fluorescent Dye (1) Fungal (5) GCGR (2) GLP Receptor (2) HDAC (15) HIV (1) iGluR (2) Isotope-Labeled Compounds (16) Melanocortin Receptor (8) Neurokinin Receptor (1) PACAP Receptor (1) Parasite (1) Penicillin-binding protein (PBP) (11) Phospholipase (1) PKC (1) Reference Standards (37) Toll-like Receptor (TLR) (2) Virus Protease (3)
By Research Areas:	Cancer (39) Cardiovascular Disease (10) Endocrinology (2) Infection (224) Inflammation/Immunology (25) Metabolic Disease (10) Neurological Disease (7)

By Targets:

Beta-lactamase (172)

Angiotensin-converting Enzyme (ACE) (5)

Antibiotic (115)

Apoptosis (12)

Autophagy (6)

Bacterial (202)

Bcl-2 Family (1)

Biochemical Assay Reagents (1)

CFTR (2)

Cholinesterase (ChE) (1)

Complement System (1)

Drug Intermediate (3)

Drug Metabolite (1)

Endogenous Metabolite (5)

Endothelin Receptor (1)

Fluorescent Dye (1)

Fungal (5)

GCGR (2)

GLP Receptor (2)

HDAC (15)

HIV (1)

iGluR (2)

Isotope-Labeled Compounds (16)

Melanocortin Receptor (8)

Neurokinin Receptor (1)

PACAP Receptor (1)

Parasite (1)

Penicillin-binding protein (PBP) (11)

Phospholipase (1)

PKC (1)

Reference Standards (37)

Toll-like Receptor (TLR) (2)

Virus Protease (3)

By Research Areas:

Cancer (39)

Cardiovascular Disease (10)

Endocrinology (2)

Infection (224)

Inflammation/Immunology (25)

Metabolic Disease (10)

Neurological Disease (7)

279

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Beta-lactamase Amyloid-β TGF-β Receptor Beta-secretase β-glucuronidase 3β-HSD TGF-beta/Smad 17β-HSD β-catenin 11β-HSD Dopamine β-hydroxylase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-136072

Xeruborbactam disodium 5 Publications Verification	Bacterial	Infection
Xeruborbactam disodium is a potent, ultra-broad-spectrum boronic acid *beta-lactamase* inhibitor. Xeruborbactam disodium inhibits key serine and metallo beta-lactamases at a nano molar range .

HY-E70012

Penicillinase	Endogenous Metabolite	Infection Metabolic Disease
Penicillinase is a beta-lactamase. beta-lactamase enzymes inactivate beta-lactam antibiotics by hydrolyzing the peptide bond of the characteristic four-membered beta-lactam ring rendering the antibiotic ineffective .

HY-138247

β-Lactamase-IN-2 EX-A4764; UUN51204	Beta-lactamase Bacterial Antibiotic	Infection
β-Lactamase-IN-2 is a *beta-lactamase* inhibitor, extracted from patent WO 2019075084 A1, compound 1. β-Lactamase-IN-2 has anti-microbial and anti-bacterial effects .

HY-N7111

Sultamicillin tosylate Sultamicillin (tosilate)	Bacterial Antibiotic	Infection
Sultamicillin tosylate is a broad-spectrum and orally active *beta-lactamase* inhibitor, an antibiotic with antibacterial activity .

HY-106791

CGP 31608	Antibiotic Bacterial	Infection
CGP 31608 is a semisynthetic penem derivative with antibacterial activity. CGP 31608 is resistant to many important beta-lactamases (including the mutationally derepressed chromosomal enzymes). CGP 31608 can be used for the research of infection .

HY-105470

BMY-28271	Bacterial	Infection
BMY-28271 is an orally active cephalosporin. BMY-28271 has a widely expanded spectrum with high activity against gram-positive and gram-negative bacteria. BMY-28271 is a poor substrate for various beta-lactamases. BMY-28271 can be used for the research of infection .

HY-136069

Xeruborbactam	Bacterial	Infection
Xeruborbactam is a potent, ultra-broad-spectrum boronic acid *beta-lactamase* inhibitor. Xeruborbactam inhibits key serine and metallo beta-lactamases at a nano molar range .

HY-19050

BRL-42715	Beta-lactamase Bacterial	Infection
BRL-42715 is a potent inhibitor of a broad range of bacterial beta-lactamases (β-lactamase) .

HY-172243

Xeruborbactam isoboxil	Beta-lactamase	Infection
Xeruborbactam isoboxil is a *beta-lactamase* inhibitor .

HY-A0035

Faropenem	Antibiotic Bacterial	Infection
Faropenem is a potent and orally active beta-lactam antibiotic. Faropenem demonstrates broad-spectrum in vitro antimicrobial activity against many gram-positive and -negative aerobes and anaerobes. Faropenem is resistant to hydrolysis by nearly all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Faropenem is developed as an oral proagent, faropenem medoxomil, for the research of respiratory tract infections .

HY-N7115

Sultamicillin	Bacterial Antibiotic	Infection
Sultamicillin is a broad-spectrum and orally active *beta-lactamase* inhibitor, an antibiotic with antibacterial activity .

HY-108062

BLI-489	Beta-lactamase Bacterial	Infection
BLI-489 is a *beta-lactamase* inhibitor. BLI-489 combined with Piperacillin (HY-B1923) inhibits infection caused by class A (including ultra-broad spectrum β-lactamase), Class C (AmpC) and Class D β-lactamase expressing pathogens .

HY-19647

Ritipenem acoxil FCE 22891; RIPM-AC; Ritipenem acetoxymethyl ester	Beta-lactamase Antibiotic Bacterial	Infection
Ritipenem acoxil (FCE 22891; RIPM-AC) is an oral active *beta-lactamase* antibiotic and can be used for study of bacterial pneumonia .

HY-W654023

Tazobactam-15N3 sodium	Isotope-Labeled Compounds	Others
Tazobactam- ¹⁵N₃ sodium is the ¹⁵N labeled isotope of Tazobactam sodium (HY-W009168) . Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class.

HY-W009168

Tazobactam sodium 15+ Cited Publications	Bacterial Antibiotic	Infection Cancer
Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class. Ceftolozane combines with Tazobactam, extends the activity of ceftolozane against many ESBL-producing Enterobacteriaceae and some Bacteroides spp..

HY-N7111R

Sultamicillin tosylate (Standard) Sultamicillin (tosilate) (Standard)	Reference Standards Bacterial Antibiotic	Infection
Sultamicillin (tosylate) (Standard) is the analytical standard of Sultamicillin (tosylate). This product is intended for research and analytical applications. Sultamicillin tosylate is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .

HY-N7115R

Sultamicillin (Standard)	Reference Standards Bacterial Antibiotic	Infection
Sultamicillin (Standard) is the analytical standard of Sultamicillin. This product is intended for research and analytical applications. Sultamicillin is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .

HY-B0334

Sulbactam 5+ Cited Publications CP45899	Bacterial Antibiotic	Infection
Sulbactam (CP45899) is a competitive, irreversible *beta-lactamase* inhibitor. Sulbactam shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex .

HY-B0334A

Sulbactam sodium 5+ Cited Publications CP45899 sodium	Bacterial Antibiotic	Infection
Sulbactam (CP45899) sodium is a competitive, irreversible *beta-lactamase* inhibitor. Sulbactam sodium shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex .

HY-14879D

ent-Avibactam sodium AVE1330A	Bacterial	Infection
ent-Avibactam sodium (AVE1330A) is a new β-lactamase inhibitor with broad-spectrum antibacterial activity. ent-Avibactam sodium, in combination with ceftazidime, exhibits significant inhibitory effects on Enterobacteriaceae that produce Ambler class A and class C beta-lactamases. The IC₅₀ value of ent-Avibactam sodium is much lower than the commonly used β-lactamase inhibitors clavulanic acid and ticarbonitrile, showing its ability to inhibit TEM-1 and P99 enzyme efficiency .

HY-A0090

Nitrofurantoin 5+ Cited Publications	Bacterial Antibiotic	Infection
Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .

HY-116571

RU44790	Antibiotic Bacterial	Infection
RU44790 is a monocyclic beta-lactam antibiotic that exerts potent activity against gram-negative bacteria and is highly resistant to hydrolysis by various beta-lactamases. RU44790 can be utilized in anti-bacteria research .

HY-B0334AS

Sulbactam-d5 sodium	Bacterial Antibiotic	Infection
Sulbactam-d₅ (sodium) is the deuterium labeled Sulbactam sodium. Sulbactam (CP45899) sodium is a competitive, irreversible beta-lactamase inhibitor. Sulbactam sodium shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex .

HY-B0334AS1

Sulbactam-d2 sodium CP45899-d₂ sodium	Bacterial Antibiotic	Infection
Sulbactam-d₂ (sodium) is the deuterium labeled Sulbactam sodium . Sulbactam (CP45899) sodium is a competitive, irreversible beta-lactamase inhibitor. Sulbactam sodium shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex .

HY-142128

Cymal-6 Cyclohexyl-hexyl-β-D-maltoside	Bacterial	Infection
Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) is a potent TEM-1 beta-lactamase inhibitor with an K_i value of 40.05 µM. Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) can be used as glycosidic surfactant .

HY-B0334R

Sulbactam (Standard) CP45899 (Standard)	Reference Standards Bacterial Antibiotic	Infection
Sulbactam (Standard) is the analytical standard of Sulbactam. This product is intended for research and analytical applications. Sulbactam (CP45899) is a competitive, irreversible *beta-lactamase* inhibitor. Sulbactam shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex .

HY-B0334AR

Sulbactam sodium (Standard) CP45899 sodium (Standard)	Reference Standards Bacterial Antibiotic	Infection
Sulbactam (sodium) (Standard) is the analytical standard of Sulbactam (sodium). This product is intended for research and analytical applications. Sulbactam (CP45899) sodium is a competitive, irreversible beta-lactamase inhibitor. Sulbactam sodium shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex .

HY-A0090R

Nitrofurantoin (Standard)	Reference Standards Bacterial Antibiotic	Infection
Nitrofurantoin (Standard) is the analytical standard of Nitrofurantoin. This product is intended for research and analytical applications. Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .

HY-B0334S

Sulbactam-d3 CP45899-d₃	Isotope-Labeled Compounds Antibiotic Bacterial	Infection
Sulbactam-d₃ (CP45899-d₃) is deuterium labeled Sulbactam. Sulbactam (CP45899) is a competitive, irreversible *beta-lactamase* inhibitor. Sulbactam shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex .

HY-A0090S

Nitrofurantoin-13C3	Isotope-Labeled Compounds Antibiotic Bacterial	Others
Nitrofurantoin- ¹³C₃ is the ¹³C labeled Nitrofurantoin (HY-A0090) . Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .

HY-163338

*Metallo-β-lactamase-IN-13*	Beta-lactamase	Infection
Metallo-β-lactamase-IN-13 (Compound 13i) is a pan *Metallo-β-Lactamase* inhibitor. Metallo-β-lactamase-IN-13 provides broader coverage of metallo-β-lactamases expressing Gram-negative (GN) bacteria. Metallo-β-lactamase-IN-13 has antibacterial activity against P. aeruginosa .

HY-144659

*Metallo-β-lactamase-IN-5*	Beta-lactamase Apoptosis Bacterial	Infection
Metallo-β-lactamase-IN-5 (compound 5c) is a potent *metallo-β-lactamases* (MBL)** inhibitor. Metallo-β-lactamase-IN-5 shows inhibitory activity against MBLs NDM-1 and VIM-1. Metallo-β-lactamase-IN-5 inhibits HUVECs with an IC₅₀ of 45 μg/mL. Metallo-β-lactamase-IN-5 plus Imipenem exhibits synergistic antimicrobial activity .

HY-115872

β-Lactamase-IN-6	Beta-lactamase Bacterial	Infection
β-Lactamase-IN-6 is a *β-Lactamase* inhibitor that shows high antibacetrial activity.

HY-19773

β-Lactamase-IN-1	Beta-lactamase Bacterial	Infection
β-Lactamase-IN-1 is an inhibitor of *β-Lactamase* extracted from patent WO2016027249A1, page 77. β-Lactamase-IN-1 can be used to prepare of tricyclic nitrogen containing compound. β-Lactamase-IN-1 can be used for the research of neisseria gonorrhea infection .

HY-139751

β-Lactamase-IN-4	Beta-lactamase Bacterial	Infection
β-Lactamase-IN-4 is a *β-lactamase* inhibitor extracted from patent WO2013149121A1, compound 708. β-Lactamase-IN-4 can be used for the research of bacterial infections .

HY-146075

β-Lactamase-IN-8	Beta-lactamase Bacterial	Infection
β-Lactamase-IN-8 (compound 20) is a potent and oral bioavailable broad-spectrum cyclic boronate *β-lactamase* inhibitor. β-Lactamase-IN-8 can be used for researching antibacteria .

HY-139779

β-Lactamase-IN-5	Beta-lactamase Bacterial	Infection
β-Lactamase-IN-5 is a *β-lactamase* inhibitor extracted from patent WO2013149121A1, compound 720. β-Lactamase-IN-5 can be used for the research of bacterial infections .

HY-163339

*Metallo-β-lactamase-IN-14*	Beta-lactamase	Infection
Metallo-β-lactamase-IN-14 (Compound 17e) is a *Metallo-β-Lactamase* inhibitor. Metallo-β-lactamase-IN-14 shows inhibition activity against VIM-1 and VIM-2. Metallo-β-lactamase-IN-14 has antibacterial activity against Gram-negative (GN) bacteria and P. aeruginosa .

HY-P2998

*β-Lactamase*	Beta-lactamase Biochemical Assay Reagents	Infection
β-Lactamase is the enzyme produced by bacteria. β-Lactamase mediates β-lactam resistance .

HY-168500

*Metallo-β-lactamase-IN-16*	Beta-lactamase Bacterial	Infection
Metallo-β-lactamase-IN-16 (compound 18) is a sulfone containing *metallo-β-lactamase* inhibitor with an anti-bacterial activity. Metallo-β-lactamase-IN-16 inhibits NDM-1 (New Dehli metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona integron-encoded metallo-β-lactamase), and VIM-2 with IC₅₀ values of 0.16 nM, 0.23 nM, 0.31 nM and 1.0 nM, respectively .

HY-144261

*Metallo-β-lactamase-IN-3*	Beta-lactamase Bacterial	Infection
Metallo-β-lactamase-IN-3 (compound 35) is a potent *metallo-β-lactamases* (MBL)** inhibitor. Metallo-β-lactamase-IN-3 shows high activity against VIM-1 and NDM-1, with IC₅₀ of 0.6 and 1.0 μM, respectively. Metallo-β-lactamase-IN-3 does not show inhibition of IMP-7 .

HY-108062A

BLI-489 hydrate	Beta-lactamase Bacterial	Infection
BLI-489 hydrate, a penem *β-lactamase* inhibitor, is active against class A and class C as well as some class D β-lactamases. The combination of Piperacillin and BLI-489 hydrate is efficacious against murine infections caused by class A (including extended-spectrum β-lactamases), class C (AmpC), and class D β-lactamase-expressing pathogens .

HY-155504

*Metallo-β-lactamase-IN-11*	Beta-lactamase Bacterial	Infection
Metallo-β-lactamase-IN-11 (compound 5f) is a *Metallo-β-lactamases* (MBLs) inhibitor, potent against bacterial metallophyllactamase CphA (IC₅₀=45 µM). Metallo-β-lactamase-IN-11 (10 µM) inhibits NDM-1 by 49% and AIM-1 by 61%. Metallo-β-lactamase-IN-11 can be used in the research of inhibiting antibiotic resistance .

HY-158977

β-Lactamase-IN-9	Beta-lactamase Bacterial	Infection
β-Lactamase-IN-9 (compound 2) is a *β-lactamase* inhibitor that can restore the sensitivity of pathogens to β-lactam antibiotics .

HY-161094

*Metallo-β-lactamase-IN-12*	Beta-lactamase Bacterial	Infection
Metallo-β-lactamase-IN-12 is a dual inhibitor of *metal β-lactamases* (MβLs (NDM-1, IMP-1)) and serine β-lactamases (SβLs (OXA-48, KPC-2)), with IC₅₀** values of 0.64 μM, 1.32 μM, 1.01 μM, and 0.57 μM, respectively. Metallo-β-lactamase-IN-12 has antibacterial activity .

HY-136306

*Metallo β-lactamase* ligand 1**	Beta-lactamase Bacterial	Infection
Metallo-beta-lactamase ligand 1 is a class B *β-lactamase* inhibitor with antibacterial activity extracted from patent WO2019221122A1, compound A .

HY-178975

β-Lactamase-IN-10	Beta-lactamase Bacterial	Infection
β-Lactamase-IN-10 is a dual metal *β-lactase* and serine *β-lactase* inhibitor. β-Lactamase-IN-10 has antibacterial activity against multiple drug-resistant bacteria. β-Lactamase-IN-10 can be used in the research of infectious conditions .

HY-144100

β-Lactamase-IN-7	Beta-lactamase Bacterial	Infection
β-Lactamase-IN-7 (compound 14) is a potent VIM-Type metallo-β-lactamase inhibitor, with K_is of 1.26 μM and 0.54 μM for VIM-1 and VIM-4, respectively. β-Lactamase-IN-7 can effectively inhibit Klebsiella pneumoniae .

HY-N15020

Izumenolide	Beta-lactamase	Infection
Izumenolide is found in the strain of Micromonospora chalcea subsp. izumensis. Izumenolide inhibited some β-lactamases, and the IC₅₀ concentration of TEM-2 β-lactamase was 0.01 μg/mL .

HY-N13977

Carpetimycin A	Beta-lactamase Bacterial	Infection
Carpetimycin A has very strong activity against Gram-positive and negative bacteria (including β-lactamase producing bacteria). Carpetimycin A has a strong inhibitory effect on *β-lactamase* .

Cat. No.	Product Name	Type

HY-129042

Cibacron Blue 3G-A 1 Publications Verification	Dyes
Cibacron Blue 3G-A is an anthraquinone dye, inhibits the R46 *β-lactamase* with a K_i value of 1.2 uM .

HY-121694

CENTA	Dyes
CENTA is a colorimetric cephalosporin substrate for β-lactamases. Upon hydrolysis by β-lacatamases, CENTA turns from light yellow to chrome yellow, which can be quantified by colorimetric detection at 405 nm as a measure of β-lactamase activity.

HY-13271AG

Tubastatin A (GMP)

Fluorescent Dye

Tubastatin A (GMP) is the Tubastatin A (HY-13271A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Tubastatin A is a potent and selective HDAC6 inhibitor with an IC₅₀ of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2).

Cat. No.	Product Name	Type

HY-13271AG

Tubastatin A (GMP)

Biochemical Assay Reagents

Cat. No.	Product Name	Target	Research Area

HY-P1195

PDZ1 Domain inhibitor peptide	iGluR	Neurological Disease
PDZ1 Domain inhibitor peptide, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide disrupts the GluR6/PSD-95 interaction and is very efficient in competing against the C terminus of GluR6 for the PDZ1 domain .

HY-18678A

Bremelanotide Acetate 1 Publications Verification PT-141 Acetate	Melanocortin Receptor	Endocrinology
Bremelanotide Acetate (PT-141 Acetate), a synthetic peptide analogue of α-MSH, is an agonist at melanocortin receptors including the MC3R and MC4R for the treatment of sexual dysfunction .

HY-P0267

Melanotan (MT)-II 1 Publications Verification	Melanocortin Receptor	Neurological Disease
Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is an injectable peptide hormone used to promote tanning.

HY-P4285

β-Aspartylalanine	Peptides	Others
β-Aspartylalanine is a substrate for β-aspartyl peptidase and used to measure β-aspartyl peptidase activity in fecal supernatants .

HY-P1195A

PDZ1 Domain inhibitor peptide TFA	iGluR	Neurological Disease
PDZ1 Domain inhibitor peptide TFA, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide TFA disrupts the GluR6/PSD-95 interaction and is very efficient in competing against the C terminus of GluR6 for the PDZ1 domain .

HY-P10278

Anantin	Peptides	Endocrinology
Anantin binds competitively to the receptor of atrial natriuretic factor (ANF) from bovine adrenal cortex (K_d = 0.6 μM) and acts as natriuretic peptide receptor A antagonist .

HY-P10135

RES-701-1	Endothelin Receptor	Cardiovascular Disease
RES-701-1 is a cyclic peptide composed of 16 common L-amino acids, acting as a specific antagonist for the ET_B receptor. RES-701-1 can inhibit the binding of 125I-ET-1 (125I-labeled Endothelin (ET)-1) to the ET_B receptor, with an IC₅₀ value of 10 nM .

HY-P2064

Lariatin A	Bacterial	Infection
Lariatins is a novel anti-mycobacterial peptides with a lasso structure produced by Rhodococcus jostii K01-B0171 .

HY-P0007

Elcatonin Carbocalcitonin	Drug Intermediate	Metabolic Disease
Elcatonin (Carbocalcitonin) is a synthetic analog of eel calcitonin. Elcatonin increases bone mineral density, inhibits bone resorption and processes a central analgesic effect .

HY-P10768

Ro 25-1553	PACAP Receptor	Neurological Disease
Ro 25-1553 is a 31 amino acid vasoactive intestinal peptide (VIP) analog, that acts as an agonist for VIP2 receptor (VPAC2 receptor). Ro 25-1553 exhibits a bronchodilator effect in nerve-induced or Carbachol (HY-B1208)-induced tracheal smooth muscle contraction in guinea pig model .

HY-P3100

Orfamide A	Parasite	Infection
Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC₅₀ value of 34.5 μg/mL .

HY-P5189A

*His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA*	Endogenous Metabolite Cholinesterase (ChE)	Others
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels .

HY-P1193

GR 82334	Neurokinin Receptor	Neurological Disease
GR 82334 is a potent and specific reversible tachykinin NK1 receptor antagonist . GR 82334 inhibits substance P-induced sensitization by blocking SP NK1 receptors in naked mole-rats .

HY-P2123A

Colistin A sulfate hydrate	Bacterial Antibiotic	Infection
Colistin A sulfate hydrate is a major component of Colistin. Colistin is a polymyxin antibiotic and can be used to combat infections caused by problematic gram-negative bacteria .

HY-106178

PMX-53 5 Publications Verification 3D53	Complement System	Cardiovascular Disease Inflammation/Immunology Cancer
PMX-53 (3D53) is a synthetic peptidic and a potent and orally active complement C5a receptor (CD88) antagonist with an IC₅₀ of 20 nM. PMX-53 is also a low-affinity MrgX2 agonist that stimulates MrgX2-mediated mast cell degranulation. PMX-53 specifically binds to C5aR1 and does not bind to the second C5aR (C5L2) and C3aR. PMX-53 has anti-inflammatory, anticancer and antiatherosclerotic effects .

HY-P1208A

PG-931 TFA	Melanocortin Receptor	Inflammation/Immunology
PG-931 TFA, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC₅₀=0.58 nM) agonist and is more selective than for the hMC3R (IC₅₀=55 nM) or the hMC5R(IC₅₀=2.4 nM). PG-931 TFA can reverse haemorrhagic shock and prevent multiple organ damage in vivo .

HY-P1209A

PG106 TFA	Melanocortin Receptor	Metabolic Disease
PG106 TFA is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC₅₀= 210 nM) and has noactivity at hMC4 receptors (EC₅₀=9900 nM) and hMC5 receptor .

HY-P1209

PG106	Melanocortin Receptor	Inflammation/Immunology
PG106 is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC₅₀=210 nM) and has noactivity at hMC4 receptors (EC₅₀=9900 nM) and hMC5 receptor .

HY-P0227

SHU 9119 3 Publications Verification	Melanocortin Receptor	Metabolic Disease
SHU 9119 is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC₅₀ values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively.

HY-P1208

PG-931	Melanocortin Receptor	Inflammation/Immunology
PG-931, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC₅₀=0.58 nM) agonist and is more selective than for the hMC3R (IC₅₀=55 nM) or the hMC5R (IC₅₀=2.4 nM). PG-931 can reverse haemorrhagic shock and prevent multiple organ damage in vivo .

HY-P5568

Siamycin III RP 71955	HIV	Infection
RP 71955 is an antimicrobial peptide against HIV-1 .

HY-P2202

Desferriferribactin	Bacterial	Others
Desferriferribactin is a cyclic peptide containing a thirteen-membered ring. Desferriferribactin is a precursor of pyoverdins .

HY-P11232

NAB815	Toll-like Receptor (TLR) Bacterial	Infection
NAB815 is a specific inhibitor of the Stx2a (K_d = 0.01 μM)/TLR4 interaction. NAB815 inhibits the neutrophil/Stx2a interaction (IC₅₀ = 0.057 μg/mL). NAB815 inhibits the formation of Stx2-containing extracellular vesicles (EVs) produced by leukocytes and platelets and reduces their toxic effects in cellular (Vero cells) and animal models (CD-1 mice). NAB815 reduces bacterial loads in the kidneys, urine, and bladders of Escherichia coli-infected mice. NAB815 is useful in the study of hemolytic uremic syndrome (HUS) .

HY-P11290

MC4-NN2-0453	Melanocortin Receptor	Metabolic Disease
MC4-NN2-0453, a α-MSH analog, is a selective MC4R agonist. MC4-NN2-0453 can be used for obesity research .

HY-P2120

Pseudobactin A	Bacterial	Others
Pseudobactin A is a non-fluorescent extracellular iron carrier produced by the plant growth-promoting bacterium Pseudomonas B10 .

HY-145632

Pemvidutide ALT-801	GLP Receptor GCGR	Metabolic Disease
Pemvidutide (ALT-801) is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide can be used in non-alcoholic steatohepatitis (NASH) and obesity research .

HY-A0248A

Polymyxin B1 1 Publications Verification	Bacterial	Infection
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-P10447

Plipastatin A1 Fengycin IX; SNA-60-367-3	Phospholipase	Inflammation/Immunology
Plipastatin A1 is a lipopeptide with enzyme inhibitory and immunosuppressive activities. Plipastatin A1 is found in Bacillus cereus and inhibits phospholipase A2 (PLA2), PLC, and PLD .

HY-145632A

Pemvidutide TFA ALT-801 TFA	GLP Receptor GCGR	Metabolic Disease
Pemvidutide (ALT-801) TFA is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide TFA can be used in non-alcoholic steatohepatitis (NASH) and obesity research .

HY-P1108A

Astressin 2B TFA 1 Publications Verification	CFTR	Others
Astressin 2B TFA is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B TFA antagonizes CRF2-mediated inhibition of gastric emptying .

HY-P1108

Astressin 2B 1 Publications Verification	CFTR	Others
Astressin 2B is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC₅₀ values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B antagonizes CRF2-mediated inhibition of gastric emptying .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7111

Sultamicillin tosylate Sultamicillin (tosilate)	Infection Classification of Application Fields Disease Research Fields	Bacterial Antibiotic
Sultamicillin tosylate is a broad-spectrum and orally active *beta-lactamase* inhibitor, an antibiotic with antibacterial activity .

HY-N15020

Izumenolide	Microorganisms Antibiotics Source classification Beta-lactam Antibiotics	Beta-lactamase
Izumenolide is found in the strain of Micromonospora chalcea subsp. izumensis. Izumenolide inhibited some β-lactamases, and the IC₅₀ concentration of TEM-2 β-lactamase was 0.01 μg/mL .

HY-N13977

Carpetimycin A	Natural Products Microorganisms Source classification	Beta-lactamase Bacterial
Carpetimycin A has very strong activity against Gram-positive and negative bacteria (including β-lactamase producing bacteria). Carpetimycin A has a strong inhibitory effect on *β-lactamase* .

HY-N13980

Carpetimycin D	Natural Products Microorganisms Source classification	Beta-lactamase Bacterial
Carpetimycin D has very strong activity against Gram-positive and negative bacteria (including β-lactamase producing bacteria). Carpetimycin D has a strong inhibitory effect on *β-lactamase* .

HY-N13978

Carpetimycin B	Natural Products Microorganisms Source classification	Beta-lactamase Bacterial
Carpetimycin B has very strong activity against Gram-positive and negative bacteria (including β-lactamase producing bacteria). Carpetimycin B has a strong inhibitory effect on *β-lactamase* .

HY-N13979

Carpetimycin C	Natural Products Microorganisms Source classification	Beta-lactamase Bacterial
Carpetimycin C has very strong activity against Gram-positive and negative bacteria (including β-lactamase producing bacteria). Carpetimycin C has a strong inhibitory effect on *β-lactamase* .

HY-N14182

Asparenomycin A	Natural Products Microorganisms Source classification	Antibiotic Bacterial
Asparenomycin A is a carbapenem antibiotic with strong β-lactamase inhibition activities .

HY-N14185

Asparenomycin C	Natural Products Microorganisms Source classification	Antibiotic Bacterial
Asparenomycin C is a carbapenem antibiotic with strong β-lactamase inhibition activities .

HY-N14183

Asparenomycin B	Natural Products Microorganisms Source classification	Antibiotic Bacterial
Asparenomycin B is a carbapenem antibiotic with strong β-lactamase inhibition activities .

HY-N14919

Olivanic acid	Natural Products Microorganisms Source classification	Beta-lactamase Antibiotic Bacterial
Olivanic acid is a β -lactam antibiotic. Olivanic acid has the effect of anti -Gram-positive bacteria and anti-Gram-negative bacteria. Olivanic acid inhibits β-lactamase .

HY-B1418

Tazobactam Maximum Cited Publications 16 Publications Verification CL-298741; YTR-830H	Infection Microorganisms Anti-inflammation/Immunoregulatory Classification of Application Fields Antibiotics Resistance Selection Source classification Antibacterial Disease Research Disease Research Fields Beta-lactam Antibiotics	Beta-lactamase Antibiotic Bacterial
Tazobactam (CL-298741) is a potent *β-lactamases* inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research .

HY-N14693

Pluracidomycin B	Natural Products Microorganisms Source classification	Antibiotic Bacterial
Pluracidomycin B is a carbapenem antibiotic. Pluracidomycin B has anti-Gram-positive bacteria and Gram-negative bacteria activity, and has the effect of inhibiting β-lactamase .

HY-N14694

Pluracidomycin C1	Natural Products Microorganisms Source classification	Antibiotic Bacterial
Pluracidomycin C1 is a carbapenem antibiotic. Pluracidomycin C1 has anti-Gram-positive bacteria and Gram-negative bacteria activity, and has the effect of inhibiting β-lactamase .

HY-N14692

Pluracidomycin A1	Natural Products Microorganisms Source classification	Antibiotic Bacterial
Pluracidomycin A1 is a carbapenem antibiotic . Pluracidomycin A1 has anti-Gram-positive bacteria and Gram-negative bacteria activity, and has the effect of inhibiting β-lactamase .

HY-N13994

Clavamycin A	Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Clavamycin A has strong anti-candida activity, and its action can be antagonized by dipeptide or tripeptide, but amino acid can not cancel its action. No antibacterial activity and no inhibition of β-lactamase .

HY-N13999

Clavamycin D	Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Clavamycin D has strong anti-candida activity, and its action can be antagonized by dipeptide or tripeptide, but amino acid can not cancel its action. No antibacterial activity and no inhibition of β-lactamase .

HY-N13997

Clavamycin C	Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Clavamycin C has strong anti-candida activity, and its action can be antagonized by dipeptide or tripeptide, but amino acid can not cancel its action. No antibacterial activity and no inhibition of β-lactamase .

HY-N13996

Clavamycin B	Microorganisms Antibiotics Source classification Other Antibiotics Beta-lactam Antibiotics	Fungal
Clavamycin B has strong anti-candida activity, and its action can be antagonized by dipeptide or tripeptide, but amino acid can not cancel its action. No antibacterial activity and no inhibition of β-lactamase .

HY-B1434

7-Aminocephalosporanic acid 2 Publications Verification 7-ACA	Infection Classification of Application Fields Disease Research Fields	Beta-lactamase Bacterial Antibiotic
7-aminocephalosporanic acid (7-ACA) is a *HSP90β* inhibitor and an antibiotic. 7-Aminocephalosporanic acid is the core chemical structure of the synthesis of cephalosporin antibiotics and an effective β-lactamase inhibitor .

HY-B1418R

Tazobactam (Standard) CL-298741 (Standard); YTR-830H (Standard)	Microorganisms Anti-inflammation/Immunoregulatory Antibiotics Resistance Selection Source classification Antibacterial Disease Research Beta-lactam Antibiotics	Beta-lactamase Reference Standards Antibiotic Bacterial
Tazobactam (Standard) is the analytical standard of Tazobactam. This product is intended for research and analytical applications. Tazobactam (CL-298741) is a potent *β-lactamases* inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research .

HY-121765

Dacisteine N,S-Diacetyl-L-cysteine	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Dacisteine (N,S-Diacetyl-L-cysteine) is a cysteine derivative and displays a less *New Delhi metallo-beta-lactamase-1 (NDM-1)* inhibitor with an IC₅₀ value of 1000 μM . Dacisteine can be used for the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation .

HY-N2598

Methyl oleate	Natural Products Classification of Application Fields Taxaceae Source classification Other Diseases Plants Disease Research Fields Taxus chinensis (Pilger) Rehd.	Bacterial
Methyl oleate is a fatty acid methyl ester (FAME) with anti-extended spectrum β-Lactamase (ESBL) potential, anticancer and antibacterial activities. Methyl oleate substantially improves the antioxidation ability but markedly impaired the antiwear capacity of zinc dialkyldithiophosphate (ZDDP). Methyl oleate is promising for research of ESBL producing multi drug resistant (MDR) pathogens .

HY-105751

Kalafungin Kalamycin; U-19718	Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial Beta-lactamase Fungal
Kalafungin is an antibiotic, antimicrobial agent and a *β-lactamase* inhibitor from marine Streptomyces, with IC₅₀ of 225.37 μM. Kalafungin destroys cell membranes. Kalafungin shows inhibitory activities against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria (such as S. aureus ATCC 33591 and S. aureus ATCC 23591), and, to a lesser extent, gram-negative bacteria .

HY-121765R

Dacisteine (Standard) N,S-Diacetyl-L-cysteine (Standard)	Natural Products Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Dacisteine (Standard) is the analytical standard of Dacisteine. This product is intended for research and analytical applications. Dacisteine (N,S-Diacetyl-L-cysteine) is a cysteine derivative and displays a less *New Delhi metallo-beta-lactamase-1 (NDM-1)* inhibitor with an IC₅₀ value of 1000 μM . Dacisteine can be used for the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation .

HY-N6736

K-252c	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids	Beta-lactamase PKC Bacterial Apoptosis
K-252c, a staurosporine analog isolated from Nocardiopsis sp., is a cell-permeable PKC inhibitor, with an IC₅₀ of 2.45 µM. K-252c induces apoptosis in human chronic myelogenous leukemia cancer cells. K-252c also inhibits β-lactamase, chymotrypsin, and malate dehydrogenase .

HY-W015786R

4-Ethoxyphenol (Standard)	Monophenols Source classification Phenols Endogenous metabolite	Reference Standards Bacterial
L-Amoxicillin (Standard) is the analytical standard of L-Amoxicillin. This product is intended for research and analytical applications. L-Amoxicillin is an antibiotic with activity against a wide range of bacterial infections. L-Amoxicillin is commonly used in antibacterial combinations when used in combination with the β-lactamase inhibitor potassium clavulanic acid. The related substances analysis method for L-Amoxicillin has been developed and validated according to the International Conference on Harmonization (ICH) guidelines, ensuring its effectiveness and accuracy in mixtures. L-Amoxicillin and some of its impurities have been further analyzed in stress testing and stability studies, providing support for optimizing its application .

HY-129200

Aspergillomarasmine A	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
Aspergillomarasmine A is a natural aminopolycarboxylic acid with potent inhibitory activity against class B metallo-β-lactamases (MBLs). Aspergillomarasmine A inactivates MBLs by removing a catalytic Zn2+ cofactor. Aspergillomarasmine A acts as a selective Zn2+ scavenger, promoting the dissociation of the metal cofactor, thereby indirectly inactivating NDM-1. Aspergillomarasmine A causes the loss of Zn2+ ions from the low-affinity binding site of NDM-1. The action of Aspergillomarasmine A results in the rapid degradation of Zn2+-deficient NDM-1, thereby enhancing its potency as a β-lactam enhancer. The mechanism of Aspergillomarasmine A has broad applicability among different Zn2+ chelators .

HY-A0248A

Polymyxin B1 1 Publications Verification	Infection Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

Cat. No.	Product Name	Chemical Structure

HY-W654023

Tazobactam-15N3 sodium
Tazobactam- ¹⁵N₃ sodium is the ¹⁵N labeled isotope of Tazobactam sodium (HY-W009168) . Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class.

HY-B0334AS

Sulbactam-d5 sodium
Sulbactam-d₅ (sodium) is the deuterium labeled Sulbactam sodium. Sulbactam (CP45899) sodium is a competitive, irreversible beta-lactamase inhibitor. Sulbactam sodium shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex .

HY-A0090S

Nitrofurantoin-13C3
Nitrofurantoin- ¹³C₃ is the ¹³C labeled Nitrofurantoin (HY-A0090) . Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .

HY-14879S2

Avibactam sodium salt-13C5
Avibactam sodium salt- ¹³C₅ (NXL-104- ¹³C₅) is ¹³C labeled Avibactam (sodium). Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam *β-lactamase* inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC₅₀s of 8 nM and 5 nM, respectively .

HY-B0555BS

Nafcillin-d5 sodium
Nafcillin-d₅ (sodium) is the deuterium labeled Nafcillin sodium. Nafcillin sodium, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium can be used for the research of staphylococcal infections .

HY-B0334AS1

Sulbactam-d2 sodium
Sulbactam-d₂ (sodium) is the deuterium labeled Sulbactam sodium . Sulbactam (CP45899) sodium is a competitive, irreversible beta-lactamase inhibitor. Sulbactam sodium shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex .

HY-B0334S

Sulbactam-d3
Sulbactam-d₃ (CP45899-d₃) is deuterium labeled Sulbactam. Sulbactam (CP45899) is a competitive, irreversible *beta-lactamase* inhibitor. Sulbactam shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex .

HY-16752S1

Relebactam-d9
Relebactam-d₉ (MK-7655-d₉) is deuterium labeled Relebactam. Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of *β-lactamases, including class A (extended-spectrum β-lactamases* and KPC) and class C (AmpC) enzymes. Relebactam shows antibacterial activity .

HY-B1256S

Cefuroxime-d3
Cefuroxime-d₃ is deuterium labeled Cefuroxime (sodium). Cefuroxime sodium is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime sodium has a broad spectrum activity against Gram-positive and Gram-negative bacteria .

HY-B1459AS

Dicloxacillin-13C4
Dicloxacillin- ¹³C₄ is the ¹³C labeled Dicloxacillin . Dicloxacillin is a β-lactam antibiotic of the penicillin family. Dicloxacillin against Gram-positive bacteria. Dicloxacillin is active against β-lactamase-producing organisms such as Staphylococcus aureus .

HY-A0088S

Cefotaxime-d3 sodium
Cefotaxime-d₃ (sodium) is the deuterium labeled Cefotaxime (sodium salt). Cefotaxime sodium salt, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .

HY-W654101

Cefotaxime-d3
Cefotaxime-d3 is the deuterium labeled Cefotaxime (HY-A0088A). Cefotaxime is the β-lactamase stable cephalosporin and the third-generation cephalosporin antibiotic. Cefotaxime possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .

HY-B1923S

Piperacillin-d5
Piperacillin-d₅ is deuterium labeled Piperacillin. Piperacillin is kind of semisynthetic penicillins. Piperacillin has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Piperacillin has shown greater activity against β-lactamase-producing organisms than the other penicillins .

HY-B1418S2

Tazobactam-15N,d2
Tazobactam- ¹⁵N,d₂ (CL-298741- ¹⁵N,d₂) is ¹⁵N and deuterium labeled Tazobactam. Tazobactam (CL-298741) is a potent *β-lactamases* inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research .

HY-B0368S

Captopril-d3

Captopril-d₃ is deuterium labeled Captopril. Captopril (SQ 14225), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC₅₀=0.025 μM) and has been widely used for research of hypertension and congestive heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC₅₀ of 7.9 μM .

HY-W740028

Cefditoren-d3 sodium

Cefditoren-d₃ (sodium) (ME 1206-d₃) is deuterium labeled Cefditoren (sodium). Cefditoren sodium (ME 1206) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren sodium has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren sodium can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .

HY-17452AS

Cefditoren Pivoxil-d3

Cefditoren Pivoxil-d₃ (Cefditoren pivoxyl-d₃) is deuterium labeled Cefditoren Pivoxil. Cefditoren Pivoxil (ME 1207) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren Pivoxil has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren Pivoxil can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .

HY-B0368S1

Captopril-13C5,15N

Captopril- ¹³C₅, ¹⁵N (SQ 14225- ¹³C₅, ¹⁵N) is ¹³C and ¹⁵N labeled Captopril. Captopril (SQ 14225), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC₅₀=0.025 μM) and has been widely used for research of hypertension and congestive heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC₅₀ of 7.9 μM .

HY-W743258

L-Amoxicillin-d4 sodium

L-Amoxicillin-d₄ sodium is the deuterium labeled L-Amoxicillin (HY-129836). L-Amoxicillin is an antibiotic with activity against a wide range of bacterial infections. L-Amoxicillin is commonly used in antibacterial combinations when used in combination with the β-lactamase inhibitor potassium clavulanic acid. The related substances analysis method for L-Amoxicillin has been developed and validated according to the International Conference on Harmonization (ICH) guidelines, ensuring its effectiveness and accuracy in mixtures. L-Amoxicillin and some of its impurities have been further analyzed in stress testing and stability studies, providing support for optimizing its application .

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