2. Anti-infection
  3. Beta-lactamase Bacterial
  4. CB-618

CB-618 is a β-lactamase inhibitor. CB-618 reversibly covalently inhibits Ambler class A, C, and some class D serine β-lactamases. CB-618 has weak antibacterial activity as a single agent, but it significantly enhances the antibacterial activity of Meropenem (HY-13678) against enzyme-producing Enterobacteriaceae. CB-618 can be used in research on drug-resistant bacteria.

For research use only. We do not sell to patients.

CB-618

CB-618 Chemical Structure

CAS No. : 1463520-70-8

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CB-618 Related Antibodies

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Metallo-β-lactamase (MBL) Serine β-lactamase (SBL)

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Description

CB-618 is a β-lactamase inhibitor. CB-618 reversibly covalently inhibits Ambler class A, C, and some class D serine β-lactamases. CB-618 has weak antibacterial activity as a single agent, but it significantly enhances the antibacterial activity of Meropenem (HY-13678) against enzyme-producing Enterobacteriaceae. CB-618 can be used in research on drug-resistant bacteria[1][2].

Molecular Weight

290.25

Formula

C8H10N4O6S
CAS No.
SMILES

O=S(ON1[C@]2([H])CC[C@@H](C3=NN=CO3)[N@@](C2)C1=O)(O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CB-618 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CB-6181463520-70-8CB618CB 618Beta-lactamaseBacterialβ-lactamaseEnterobacteriaceaepharmacodynamicsvaborbactamInhibitorinhibitorinhibit

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