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Results for "

NO synthase (iNOS)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	NO Synthase (51) PGE synthase (2) Antibiotic (2) Apoptosis (6) Bacterial (6) Bcl-2 Family (1) Caspase (2) COX (4) Endogenous Metabolite (3) Fungal (1) Histone Acetyltransferase (1) HSV (1) IKK (1) Interleukin Related (1) JNK (1) NF-κB (5) NOD-like Receptor (NLR) (1) p38 MAPK (2) PKC (1) Reference Standards (4)
By Research Areas:	Cancer (11) Cardiovascular Disease (9) Infection (4) Inflammation/Immunology (40) Metabolic Disease (4) Neurological Disease (13)

Inhibitors & Agonists

Biochemical Assay Reagents

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Isotope-Labeled Compounds

Antibodies

Targets Recommended: NO Synthase PGE synthase Thymidylate Synthase ATP Synthase Acetolactate Synthase (ALS) Glucosylceramide Synthase (GCS) Fatty Acid Synthase (FASN) Cyclic GMP-AMP Synthase WNK Kinase GSK-3

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-145846

iNOs-IN-1 1 Publications Verification	NO Synthase Interleukin Related	Inflammation/Immunology
iNOs-IN-1 (YPW) is a potent inducible nitric oxide synthase (iNOS) inhibitor. iNOs-IN-1 can significantly inhibit the expression of IL-6 and iNOS, as well as reduce LPS-induced NO generation with dose-dependent manner in mouse macrophages. Anti-inflammatory effects .

HY-W003969

Aminopicoline Ascensil	NO Synthase	Others
Aminopicoline (Ascensil) is a potent and nonselective inhibitor of NO synthase (NOS) isoenzymes (iNOS, nNOS, eNOS) .

HY-107584

BYK 191023 dihydrochloride	NO Synthase	Metabolic Disease
BYK 191023 is a highly selective inducible nitric-oxide synthase (iNOS) inhibitor. BYK 191023 interacts with the catalytic center of the enzyme. BYK 191023 can be used to study the in vivo and in vitro effects mediated by iNOS .

HY-124508

Lambertellin	Antibiotic Bacterial Fungal p38 MAPK NF-κB	Infection Inflammation/Immunology
Lambertellin is an effective antibiotic that can be used as a bactericide and as a fungicide. Lambertellin exerts its anti-inflammatory effect in LPS (HY-D1056)-stimulated RAW 264.7 macrophage cells by modulating the activation of the MAPK and NF-κB signaling pathways .

HY-133098

Juncutol	NO Synthase	Inflammation/Immunology
Juncutol is a potent inducible nitric oxide synthase (iNOS) inhibitor. Juncutol decreases the LPS (HY-D1056)-stimulated iNOS protein expression .

HY-146309

iNOS-IN-2	NO Synthase	Inflammation/Immunology
iNOS-IN-2 (Compound 53) is a potent down-regulator of inducible nitric oxide synthase (iNOS) protein. iNOS-IN-2 effectively inhibits the NO production (IC₅₀=6.4 μM). iNOS-IN-2 has a potential therapeutic effect on chronic inflammation .

HY-150055

iNOs-IN-3	NO Synthase	Inflammation/Immunology
iNOs-IN-3 (Compound 2d) is an orally active nitric oxide synthase (iNOS) inhibitor (IC₅₀=3.342 µM). iNOs-IN-3 shows anti-inflammatory activity and can be used in LPS-induced acute lung injury (ALI) research .

HY-161513

iNOS/COX-2-IN-1	COX NO Synthase	Inflammation/Immunology
iNOS/COX-2-IN-1 (Compound 12e) is an inhibitor of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS). iNOS/COX-2-IN-1 inhibits the NF-κB and MAPKs signaling pathways and thus exerts anti-inflammatory effects .

HY-122060

BYK 191023	NO Synthase	Metabolic Disease
BYK 191023 is a selective and L-arginine competitive inducible nitric-oxide synthase inhibitor with an IC₅₀ value of 86 nM, 17 µM, 162 µM for inducible (iNOS), neuronal (nNOS), and endothelial (eNOS) NO synthases respectively .

HY-139135

Methyl-L-NIO hydrochloride	NO Synthase	Others
Methyl-L-NIO (compound 2d) hydrochloride is a potential selective inhibitor (IC₅₀: 70 μM) of dimethylarginine dimethylaminohydrolase hDDAH. Methyl-L-NIO also has inhibitory activity against NO synthase. The inhibition rates of Methyl-L-NIO on different isoforms of NO synthase at a concentration of 100 μM are 77% (nNOS), 20% (eNOS), and 72% (iNOS) respectively; the inhibition rates at a concentration of 1 mM are 100% (nNOS), 85% (eNOS), 100% (iNOS) .

HY-W408607

N-Benzylacetamidine hydrobromide	NO Synthase	Inflammation/Immunology
N-Benzylacetamidine (hydrobromide) is a acetamidine compound. N-Benzylacetamidine (hydrobromide) is a selective inducible nitric oxide synthase (iNOS) inhibitor with an IC₅₀ of 0.20 μM .

HY-131929

AE-ITU dihydrobromide	NO Synthase	Inflammation/Immunology
AE-ITU dihydrobromide is the dihydrobromide form of AE-ITU. AE-ITU dihydrobromide is a selective inhibitor for inducible NO synthase (iNOS), and attenuates the liver dysfunction caused by endotoxaemia in rats .

HY-W003969R

Aminopicoline (Standard) Ascensil (Standard)	Reference Standards NO Synthase	Others
Aminopicoline (Standard) is the analytical standard of Aminopicoline. This product is intended for research and analytical applications. Aminopicoline (Ascensil) is a potent and nonselective inhibitor of NO synthase (NOS) isoenzymes (iNOS, nNOS, eNOS) .

HY-N6770

Curvularin (S)-Curvularin	NO Synthase	Infection Inflammation/Immunology
Curvularin, a fungal metabolite and a potent mycotoxin naturally isolated from Curvularia lunata, inhibits cytokine-induced nitric oxide synthase (iNOS), with an IC₅₀ of 9.5 µM .

HY-79457

S-Methylisothiourea sulfate 1 Publications Verification	NO Synthase HSV	Infection Inflammation/Immunology
S-Methylisothiourea sulfate is a potent, selective and competitive inhibitor of inducible nitric oxide synthase (iNOS). S-Methylisothiourea sulfate exerts beneficial effects in rodent models of septic shock .

HY-N1382

Asperuloside 2 Publications Verification	NO Synthase	Metabolic Disease Inflammation/Immunology
Asperuloside is an iridoid isolated from Hedyotis diffusa, with anti-inflammatory activity. Asperuloside inhibits inducible nitric oxide synthase (iNOS), suppresses NF-κB and MAPK signaling pathways .

HY-122063

FR260330	NO Synthase	Inflammation/Immunology
FR260330 is a selective, orally active inhibitor for inducible nitric oxide synthase (iNOS) through suppression of iNOS dimerization. FR260330 inhibits the NO accumulation in rat splenocytes and human DLD-110 cells, with IC₅₀ of 27 and 10 nM. FR260330 ameliorates the Lipopolysaccharides (HY-D1056)-induced inflammatory diseases in rats model .

HY-18730

1400W W1400	NO Synthase Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
1400W is a slow, tight binding, and highly selective inducible nitric-oxide synthase (iNOS) inhibitor, with a K_d value ≤ 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex, and improving the spatial memory dysfunction caused by acute hypobaric hypoxia-reoxygenation .

HY-114798

Rabelomycin	Antibiotic Bacterial NO Synthase	Infection Neurological Disease
Rabelomycin is antibiotic, which exhibits antimicrobial activity against gram positive bacteria. Rabelomycin exhibits inhibitory activity against inducible nitric oxide synthase (iNOS) with an IC₅₀ of 63.9 μM .

HY-N0268

Irisflorentin 2 Publications Verification	NO Synthase	Inflammation/Immunology
Irisflorentin, a naturally occurring isoflavone, is an abundant active constituent in Belamcanda chinensis. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Anti-inflammatory activity .

HY-136341

7,8-Dihydroneopterin	Apoptosis NO Synthase Endogenous Metabolite	Neurological Disease Inflammation/Immunology
7,8-Dihydroneopterin, an inflammation marker, induces cellular apoptosis in astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. 7,8-Dihydroneopterin can be used in the research of neurodegenerative diseases .

HY-138564

NOS-IN-1	NO Synthase	Inflammation/Immunology
NOS-IN-1 is a potent and orally active *NO synthase* (NOS) isoforms inhibitor with IC₅₀s of 0.1 μM, 1.1 μM, and 0.2 μM for human iNOS (hiNOS), heNOS and hnNOS**, respectively .

HY-101316

TRIM	NO Synthase	Neurological Disease
TRIM is a potent nitric oxide synthase inhibitor. TRIM inhibits mouse cerebellar nNOS and rat lung iNOS in vitro with IC₅₀ values of 28.2 and 27.0 µM, respectively. Antidepressant- and anxiolytic-like effects .

HY-12122A

AR-C102222 hydrochloride	NO Synthase	Neurological Disease Inflammation/Immunology
AR-C102222 hydrochloride is a potent, competitive, orally active and highly selective inducible nitric oxide synthase (iNOS) inhibitor, with an IC₅₀ of 37 nM . AR-C102222 hydrochloride has antinociception and anti-inflammatory activities .

HY-N11085

Isophysalin A	NO Synthase IKK	Inflammation/Immunology
Isophysalin A is a physalin with alpha and beta unsaturated ketone components. Isophysalin A binds to GSH and targets multiple cysteine residues on IKKβ. Isophysalin A also inhibits inducible NO synthase (iNOS) and nitric oxide (NO) production, showing anti-inflammatory activity .

HY-18732A

L-NMMA acetate 5+ Cited Publications Tilarginine acetate; Methylarginine acetate	NO Synthase Endogenous Metabolite	Cardiovascular Disease Cancer
L-NMMA acetate is a nitric oxide synthase inhibitor of all NOS isoforms including NOS1, NOS2, and NOS3. The K_i values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 μM, respectively.

HY-18731

1400W Dihydrochloride Maximum Cited Publications 24 Publications Verification	NO Synthase Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
1400W dihydrochloride is the dihydrochloride form of 1400W (HY-18730). 1400W is a slow, tight binding, and highly selective inducible nitric-oxide synthase (iNOS) inhibitor, with a K_d value ≤ 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex, and improving the spatial memory dysfunction caused by acute hypobaric hypoxia-reoxygenation .

HY-146161

COX-2/NO-IN-1	COX NO Synthase	Inflammation/Immunology
COX-2/NO-IN-1 is an orally active nitric oxide synthase (iNOS), COX-2 expression and NO (IC₅₀ of 3.52 μM) inhibitor. COX-2/NO-IN-1 has anti-inflammatory effects .

HY-164361

2′-Hydroxy-2,3-dimethoxychalcone	NO Synthase	Inflammation/Immunology
α-Gracinoic acid is a Chalcone (HY-121054) derivative with anti-inflammatory activity. α-Gracinoic acid inhibits nitric oxide production catalyzed by inducible nitric oxide synthase (iNOS) in lipopolysaccharide (LPS)-treated RAW 264.7 cells .

HY-135224

1,4-PBIT dihydrobromide 1,4-PB-ITU dihydrobromide	NO Synthase	Cancer
1,4-PBIT (1,4-PB-ITU) dihydrobromide (compound 46) is a potent *nitric oxide synthases* (NOS) inhibitor, with K_i** values of 7.6 nM, 360 nM, and 16 nM for the inducible (iNOS), endothelial (eNOS), and neuronal (nNOS) isozymes, respectively .

HY-N1382R

Asperuloside (Standard)	Reference Standards NO Synthase	Metabolic Disease Inflammation/Immunology
Asperuloside (Standard) is the analytical standard of Asperuloside. This product is intended for research and analytical applications. Asperuloside is an iridoid isolated from Hedyotis diffusa, with anti-inflammatory activity. Asperuloside inhibits inducible nitric oxide synthase (iNOS), suppresses NF-κB and MAPK signaling pathways .

HY-12119B

GW274150 dihydrochloride	NO Synthase	Neurological Disease Inflammation/Immunology
GW274150 (dihydrochloride) is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC₅₀=2.19 μM; K_d=40 nM) and rat *iNOS* (ED₅₀=1.15 μM). GW274150 (dihydrochloride) displays less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 (dihydrochloride) exerts a protective role in an acute model of lung injury inflammation .

HY-12119

GW274150 2 Publications Verification	NO Synthase	Neurological Disease Inflammation/Immunology
GW274150 is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC₅₀=2.19 μM; K_d=40 nM) and rat *iNOS* (ED₅₀=1.15 μM). GW274150 also displays less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 exerts a protective role in an acute model of lung injury inflammation .

HY-12119A

GW274150 phosphate 2 Publications Verification	NO Synthase	Neurological Disease Inflammation/Immunology
GW274150 phosphate is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC₅₀=2.19 μM; K_d=40 nM) and rat *iNOS* (ED₅₀=1.15 μM). GW274150 phosphate displays less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 phosphate exerts a protective role in an acute model of lung injury inflammation .

HY-N0268R

Irisflorentin (Standard)	Reference Standards NO Synthase	Inflammation/Immunology
Irisflorentin (Standard) is the analytical standard of Irisflorentin. This product is intended for research and analytical applications. Irisflorentin, a naturally occurring isoflavone, is an abundant active constituent in Belamcanda chinensis. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Anti-inflammatory activity .

HY-138454

MEG hemisulfate Mercaptoethylguanidine hemisulfate	NO Synthase	Inflammation/Immunology
MEG (Mercaptoethylguanidine) hemisulfate is a potent and selective inhibitor of the inducible NO synthase (iNOS), with EC₅₀s of 11.5, 110, and 60 μM for *iNOS, ecNOS, and bNOS* respectively in tissue homogenates. MEG hemisulfate is also a potent scavenger of peroxynitrite and inhibits peroxynitrite-induced oxidative processes. MEG hemisulfate has a protective effect in many experimental models of inflammation, including ischemia/reperfusion injury, periodontitis, hemorrhagic shock, inflammatory bowel disease, and endotoxic and septic shock .

HY-100986

L-NIO dihydrochloride 1 Publications Verification	NO Synthase	Cardiovascular Disease
L-NIO dihydrochloride is a potent, non-selective and NADPH-dependent *nitric oxide synthase* (NOS) inhibitor, with K_i*s of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS*), respectively . L-NIO dihydrochloride induces a consistentfocal ischemic infarctin rats .

HY-100986B

L-NIO	NO Synthase	Cardiovascular Disease
L-NIO is a potent, non-selective and NADPH-dependent *nitric oxide synthase* (NOS) inhibitor, with K_i*s of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS*), respectively . L-NIO induces a consistentfocal ischemic infarctin rats .

HY-N6966R

Ethyl Caffeate (Standard)	NF-κB NO Synthase COX PGE synthase	Inflammation/Immunology Cancer
Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin .

HY-N6966

Ethyl Caffeate 1 Publications Verification	NF-κB NO Synthase COX PGE synthase	Inflammation/Immunology Cancer
Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E₂ (PGE₂) in vitro or in mouse skin .

HY-18731R

1400W Dihydrochloride (Standard)	NO Synthase Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
1400W (Dihydrochloride) (Standard) is the analytical standard of 1400W (Dihydrochloride). This product is intended for research and analytical applications. 1400W dihydrochloride is the dihydrochloride form of 1400W (HY-18730). 1400W is a slow, tight binding, and highly selective inducible nitric-oxide synthase (iNOS) inhibitor, with a Kd value ≤ 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex, and improving the spatial memory dysfunction caused by acute hypobaric hypoxia-reoxygenation .

HY-18732AR

L-NMMA acetate (Standard)	NO Synthase Endogenous Metabolite	Cardiovascular Disease Cancer
L-NMMA (acetate) (Standard) is the analytical standard of L-NMMA (acetate). This product is intended for research and analytical applications. L-NMMA acetate is a nitric oxide synthase inhibitor of all NOS isoforms including NOS1, NOS2, and NOS3. The Ki values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 μM, respectively.

HY-N12224

1-Heptadecanoyl-rac-glycerol MG(17:0/0:0/0:0); 1-HeptadecaNOin	NO Synthase	Inflammation/Immunology
1-Heptadecanoyl-rac-glycerol (1-Heptadecanoin) is a glyceride compound with anti-inflammatory activity. 1-Heptadecanoyl-rac-glycerol inhibits the occurrence of inflammation by suppressing the expression of inducible nitric oxide synthase (iNOS) related to inflammation. 1-Heptadecanoyl-rac-glycerol can be used for research on diseases related to inflammation .

HY-118160

PPM-18 NSC 73233	NO Synthase	Inflammation/Immunology Cancer
PPM-18 (NSC 73233), a potent anti-inflammatory agent, inhibits nitric oxide synthase expression. PPM-18 is a potent inhibitor of iNOS expression by blocking the binding of NF-κB to promoter . PPM-18, an analog of Vitamin K, induces autophagy and apoptosis in bladder cancer cells through ROS and AMPK signaling pathways .

HY-176779

Guanidino ethyl disulfide	NO Synthase	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Guanidino ethyl disulfide (GED) (Compound 23) is a *NO Synthase* (NOS) inhibitor with EC₅₀*s of 110, 630 and 180  μM for iNOS*, eNOS and bNOS, respectivly. Guanidino ethyl disulfide effectively inhibits nitrite production in J774.2 macrophages. Guanidino ethyl disulfide can be used for circulatory shock, inflammation and neurological diseases research .

HY-117786

Go 7874	PKC	Neurological Disease
Go 7874 is a protein kinase C (PKC) inhibitor. Go 7874 mediated neuroprotection against LPS/IFNg-induced neuronal cell death in an immune-mediated neurotoxicity model, not through PKC activity. In contrast, the neuroprotective mechanism of Go 7874 involves inhibition of inducible nitric oxide synthase (iNOS) gene expression, followed by reduced nitric oxide (NO) production .

HY-118700

2-Iminobiotin GuanidiNObiotin	NO Synthase	Neurological Disease
2-Iminobiotin (Guanidinobiotin) is a biotin (vitamin H or B7) analog. 2-Iminobiotin is a reversible nitric oxide synthases inhibitor with K_is of 21.8 and 37.5μM for murine *iNOS* and rat n-cNOS, respectively . 2-Iminobiotin superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage .

HY-111954

(+)-Erinacin A Erinacine A	Apoptosis JNK NF-κB Histone Acetyltransferase NO Synthase Bcl-2 Family p38 MAPK Caspase	Neurological Disease Inflammation/Immunology Cancer
(+)-Erinacin A (Erinacine A) is a cyanoditerpenoid isolated from Hericium erinaceus with anticancer, anti-inflammatory and neuroprotective activities. (+)-Erinacin A can induce cancer cell death by activating extrinsic and intrinsic apoptosis pathways. (+)-Erinacin A can also inhibit the expression of NO synthase (iNOS) and the production of nitrotyrosine to exert inflammatory and neuroprotective effects, thereby reducing ischemic brain damage .

HY-146765

AMS-17	NOD-like Receptor (NLR)	Neurological Disease Inflammation/Immunology
AMS-17 is a potent NLRP3 inhibitor, inhibiting microglia activation in vitro and in vivo. AMS-17 also inhibits cytokines such as caspase-1, TNF-α, IL-1β and inducible nitric oxide synthase (iNOS) in N9 cells. AMS-17 can be used for researching inflammation-associated neurological disorders, such as vascular dementia (VaD) .

HY-118700A

2-Iminobiotin hydrobromide GuanidiNObiotin hydrobromide	NO Synthase	Neurological Disease
2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with K_is of 21.8 and 37.5 μM for murine *iNOS* and rat n-cNOS, respectively . 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage .

Cat. No.	Product Name	Type

HY-W251598B

Sodium bicarbonate, for molecular biology

Sodium hydrogen carbonate for molecular biology; Soda bicarbonate for molecular biology

Buffer Reagents

Sodium bicarbonate, for molecular biology (Sodium hydrogen carbonate for molecular biolog; Soda bicarbonate for molecular biolog) is an inorganic salt that is neutral to slightly alkaline and easily decomposes when exposed to moisture in the air. Sodium bicarbonate can maintain the pH of the culture medium, thereby affecting the expression of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) production in macrophages and reversing the acidosis of the tumor microenvironment. Sodium bicarbonate is widely used in the fields of food, medicine, cosmetics, etc. Its main uses include buffers, flavoring agents, disinfectants, pharmaceuticals, and proton gradient regulators. Sodium bicarbonate is also commonly used as an antacid to inhibit gastrointestinal diseases, neutralize gastric acid, and reduce gastric discomfort .

HY-W251598C

Sodium bicarbonate, for cell culture

Sodium hydrogen carbonate for cell culture; Soda bicarbonate for cell culture

Buffer Reagents

Sodium bicarbonate, for cell culture (Sodium hydrogen carbonate for cell culture; Soda bicarbonate for cell culture) is an inorganic salt that is neutral to slightly alkaline and easily decomposes when exposed to moisture in the air. Sodium bicarbonate, for cell culture can maintain the pH of the culture medium, thereby affecting the expression of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) production in macrophages and reversing the acidosis of the tumor microenvironment. Sodium bicarbonate is widely used in the fields of food, medicine, cosmetics, etc. Its main uses include buffers, flavoring agents, disinfectants, pharmaceuticals, and proton gradient regulators. Sodium bicarbonate is also commonly used as an antacid to inhibit gastrointestinal diseases, neutralize gastric acid, and reduce gastric discomfort .

HY-W251598I

Sodium bicarbonate, meets analytical specification of Ph. Eur., BP, USP, FCC, E500

Sodium hydrogen carbonate, meets analytical specification of Ph. Eur., BP, USP, FCC, E500

Buffer Reagents

Sodium bicarbonate, meets analytical specification of Ph. Eur., BP, USP, FCC, E500 is an inorganic salt that is neutral to slightly alkaline and easily decomposes when exposed to moisture in the air. Sodium bicarbonate can maintain the pH of the culture medium, thereby affecting the expression of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) production in macrophages and reversing the acidosis of the tumor microenvironment. Sodium bicarbonate is widely used in the fields of food, medicine, cosmetics, etc. Its main uses include buffers, flavoring agents, disinfectants, pharmaceuticals, and proton gradient regulators. Sodium bicarbonate is also commonly used as an antacid to inhibit gastrointestinal diseases, neutralize gastric acid, and reduce gastric discomfort .

Cat. No.	Product Name	Chemical Structure

HY-W251598S

Bicarbonate-13C sodium

Bicarbonate- ¹³C sodium is the ¹³C-labeled Sodium bicarbonate (HY-Y0756). Sodium bicarbonate is an inorganic salt that is neutral to slightly alkaline and easily decomposes when exposed to moisture in the air. Sodium bicarbonate can maintain the pH of the culture medium, thereby affecting the expression of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) production in macrophages and reversing the acidosis of the tumor microenvironment. Sodium bicarbonate is widely used in the fields of food, medicine, cosmetics, etc. Its main uses include buffers, flavoring agents, disinfectants, pharmaceuticals, and proton gradient regulators. Sodium bicarbonate is also commonly used as an antacid to inhibit gastrointestinal diseases, neutralize gastric acid, and reduce gastric discomfort .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80725

	iNOS Antibody 2 Publications Verification NOS2; NOS2A; Nitric oxide synthase; inducible; Hepatocyte NOS; HEP-NOS; Inducible NO synthase; Inducible NOS; iNOS; NOS type II; Peptidyl-cysteine S-nitrosylase NOS2	WB, IHC-P, IHC-F, ICC/IF	Human, Mouse, Rat
	iNOS Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to iNOS.

HY-P86080

	iNOS Antibody (YA5772) NOS2; NOS2A; Nitric oxide synthase; inducible; Hepatocyte NOS; HEP-NOS; Inducible NO synthase; Inducible NOS; iNOS; NOS type II; Peptidyl-cysteine S-nitrosylase NOS2	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	iNOS Antibody (YA5772) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to iNOS.

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NO synthase (iNOS)

Inhibitors & Agonists

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