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Results for "

MG

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (3) Adrenergic Receptor (4) Amino Acid Derivatives (1) Apoptosis (16) Autophagy (5) Bacterial (2) Biochemical Assay Reagents (3) c-Kit (2) c-Met/HGFR (1) Cathepsin (2) Cholinesterase (ChE) (1) Deubiquitinase (1) Discoidin Domain Receptor (2) DNA/RNA Synthesis (2) Dopamine Receptor (4) EGFR (1) Endogenous Metabolite (2) Epigenetic Reader Domain (1) Ferroptosis (1) FLT3 (2) Fluorescent Dye (3) Fungal (3) GABA Receptor (2) Glycosidase (1) GnRH Receptor (1) Histamine Receptor (3) Histone Acetyltransferase (1) HuR (1) IFNAR (2) IKZF Family (1) Interleukin Related (1) mGluR (1) MicroRNA (1) Microtubule/Tubulin (3) MMP (1) Molecular Glues (2) mRNA (2) nAChR (2) NF-κB (2) NO Synthase (2) Oxysterol-binding Protein-related Protein (ORP) (1) Parasite (1) Peptide-Drug Conjugates (PDCs) (2) Phosphatase (2) Phosphodiesterase (PDE) (1) PINK1/Parkin (1) Potassium Channel (1) PROTACs (4) Proteasome (8) Reactive Oxygen Species (ROS) (4) Reference Standards (2) RSV (2) Small Interfering RNA (siRNA) (4) Src (1) STAT (1) Tau Protein (2) Tim3 (1) Tissue Factor Pathway Inhibitor (TFPI) (1) TNF Receptor (2) Toll-like Receptor (TLR) (2) Transmembrane Glycoprotein (1) Trk Receptor (2) VEGFR (3) VISTA (1)
By Research Areas:	Cancer (39) Cardiovascular Disease (7) Endocrinology (4) Infection (3) Inflammation/Immunology (16) Metabolic Disease (2) Neurological Disease (14)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) mRNA (2) Adjuvant (2) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (2) siRNAs (4)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15887

MG 149 10+ Cited Publications Tip60 HAT inhibitor	Histone Acetyltransferase Epigenetic Reader Domain Apoptosis PINK1/Parkin	Cardiovascular Disease Neurological Disease Cancer
MG149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC₅₀ of 74 uM, similar potentcy for MOF (IC₅₀ = 47 uM); little potent for PCAF and p300 (IC₅₀ >200 uM). MG 149 inhibits KAT8 and blocks PINK1 kinase activity. MG 149 can induce mitochondrial depolarization and promote PINK1 dependent mitochondrial clearance. MG 149 can reverse chronic restraint stress (CRS) induced hypertension and related molecular changes. MG 149 commonly used in research on diseases such as hypertension and Parkinson's disease .

HY-130122

MG-277	Molecular Glues PROTACs Apoptosis	Cancer
MG-277, a molecular glue degrader, effectively induces degradation of a translation termination factor based on Cereblon E3 ligand, GSPT1, with a DC₅₀ of 1.3 nM. MG-277 potently inhibits tumor cell growth in a p53-independent manner, with IC₅₀s of 3.5 nM for RS4;11 cells and 3.4 nM for p53 mutant RS4;11/IRMI-2 cells, respectively. Anticancer activity .

HY-139307

MG-2119	Tau Protein	Neurological Disease
MG-2119 is a potent monomeric tau and α-syn aggregation inhibitor. MG-2119 is a potential agent for neurological disorders research .

HY-108552

MG-115 1 Publications Verification	Proteasome Apoptosis	Cancer
MG-115 is a potent and reversible proteasome inhibitor, with K_is of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteasome, induces p53-dependent apoptosis .

HY-U00110

MG 1	Adrenergic Receptor	Cardiovascular Disease Endocrinology
MG 1 is an α1 adrenergic receptor antagonist.

HY-101828

Guaiapate Klamar; MG 5454	Others	Inflammation/Immunology
Guaiapate is an antitussive agent.

HY-RS08396

MGAM Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MGAM Human Pre-designed siRNA Set A contains three designed siRNAs for MGAM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MGAM Human Pre-designed siRNA Set A MGAM Human Pre-designed siRNA Set A

HY-168183

MG28	Apoptosis	Cancer
MG28 exhibits a remarkable cytotoxic effect, which is the likely consequence of its direct and intense DNA damaging activity. MG28 can be used for the research of cancer .

HY-P991475

MG-1131	Transmembrane Glycoprotein NF-κB IFNAR	Cancer
MG-1131 is a human monoclonal antibody (mAb) targeting TIGIT. MG-1131 activates NF-κB signaling in T cells and enhances NK-mediated tumor killing activity in a PVR-dependent manner. MG-1131 blocks TIGIT to increase IFN-γ secretion. MG-1131 can be used in anti-tumor immunity research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-160481

MG-1102	Tau Protein MicroRNA	Neurological Disease
MG-1102 is first-in-class dual binder of monomeric tau and pre-miRNA-146a. MG-1102 shows specific inhibition of miRNA146a with IC₅₀s of 0.21 mM and 0.36 mM specific inhibition of doublelabeled pre-miRNA146a and mono-labeled pre-miRNA146a, respectively. MG-1102 interacts with tau monomers with a K_d of 3.21 mM by surface plasmon resonance (SPR). MG-1102 is a potential multi-target-directed ligands (MTDLs) for Alzheimer’s disease (AD) .

HY-13259

MG-132 Maximum Cited Publications 1689 Publications Verification Z-Leu-Leu-Leu-al; MG132	Proteasome Autophagy Apoptosis	Cancer
MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC₅₀s of 100 nM and 1.2 μM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis .

HY-Q25865

MG-V-53	VISTA	Cancer
MG-V-53 is a potent small molecule V domain T-cell activating immunoglobulin suppressor (VISTA) inhibitor with IC₅₀ value of 121 nM. MG-V-53 has antitumor activity .

HY-175324

MG-HuR2	Molecular Glues HuR	Cancer
MG-HuR2 is a molecular glue degrader targeting the oncogenic RNA-binding protein HuR (IC₅₀=0.5 μM). MG-HuR2 is promising for research of HuR-overexpressing malignancies (e.g., breast cancer) .

HY-P11315

MG1 peptide	Biochemical Assay Reagents	Neurological Disease
MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. MG1 peptide can be used for drug delivery for ischemic stroke research .

HY-159886

MG-C-30	TNF Receptor	Inflammation/Immunology
MG-C-30 is an orally active agonist for CD27 with an EC₅₀ of 0.84 μM. MG-C-30 activates NK cells and T cell co-stimulatory signals, and enhances immune response. MG-C-30 exhibits antitumor efficacy in mouse EG7-OVA model .

HY-159884

MG-T-19	Tim3 TNF Receptor IFNAR	Cancer
MG-T-19 is an effective TIM-3 inhibitor that can suppress the interaction of TIM-3 with PtdSer, CEACAM1, and Gal-9. MG-T-19 can increase the production of tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) in peripheral blood mononuclear cells (PBMCs) from healthy donors, and enhance the ability of PBMCs to inhibit the proliferation of Kasumi-1 cells (an acute myelogenous leukemia cell line) .

HY-126179

Fenquizone MG-13054	Potassium Channel	Cardiovascular Disease Metabolic Disease
Fenquizone (MG-13054) is an orally active diuretic. Fenquizone acts primarily on the diluting segment of the nephron cortex, similar to thiazide diuretics. Fenquizone demonstrates diuretic and natriuretic potency and duration of action comparable to thiazide diuretics but weaker than loop diuretics. Fenquizone reduces CH₂O without affecting TCH₂O, does not increase calcium/phosphate excretion, and has no loop or collecting duct effects. Fenquizone is used in the study of edema and hypertension .

HY-P991379

MG1113A	Tissue Factor Pathway Inhibitor (TFPI)	Others
MG1113A is a human monoclonal antibody (mAb) targeting TFPI. MG1113A can be used in Haemophilia research.

HY-173500

MG-3C	MMP Apoptosis EGFR STAT	Cancer
MG-3C is a potent matrix metalloproteinase 9 (MMP-9) inhibitor. MG-3C can selectively kill non-small-cell lung cancer (NSCLC) cells harboring the EGFR T790M mutation. MG-3C blocks the EGFR/STAT3 signaling pathway, inducing G2/M phase arrest, growth inhibition, and apoptosis of cancer cells. MG-3C is promising for research of lung cancer .

HY-159885

MG-B-28	Apoptosis	Cancer
MG-B-28 is an inhibitor of BTLA-HVEM with an IC₅₀ value of 906 nM. MG-B-28 promotes T-cell activation in a dose-dependent manner by blocking the BTLA-HVEM interaction .

HY-107672

MG624 Stilonium iodide	nAChR	Neurological Disease
MG624 is a potent and selective neuronal α7 nAChR antagonist with a K_i of 106 nM .

HY-157998

mG2N001	mGluR Src	Others
mG2N001 is a negative allosteric modulator (NAM) (IC₅₀: 93 nM) of the metabotropic glutamate receptor mGluR2 and binds to mGluR2 as an antagonist (Ki: 63 nM). mG2N001 is microparticle- and plasma-stable, and its radioisotope ^[11C]mG2N001 can be used in PET imaging. ^[11C]mG2N001 has good brain heterogeneity and brain penetration, and can selectively accumulate in mGluR2-rich regions, producing high-contrast brain images .

HY-P990910

Comekibart MG-K10	Interleukin Related	Inflammation/Immunology
HY-P990910 is an IL4R-targeting IgG4κ type humanized antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .

HY-13259D

MG-132 (negative control)	Proteasome	Cancer
MG-132 negative control is the negative control form of MG-132 (HY-13259). MG-132 is a potent proteasome and calpain inhibitor .

HY-136476

Mg(II) protoporphyrin IX	Others	Others
Mg(II) protoporphyrin IX is a precursor of chlorophyll in Chlorella. Mg(II) protoporphyrin IX is a negative effector of nuclear photosynthetic gene expression. Mg(II) protoporphyrin IX can be used for the research of signaling molecule implicated in plastid-to-nucleus communication .

HY-16961

Sitravatinib 5+ Cited Publications MGCD516; MG-516	VEGFR c-Kit FLT3 Discoidin Domain Receptor Trk Receptor	Inflammation/Immunology Cancer
Sitravatinib (MGCD516) is an orally bioavailable receptor tyrosine kinase (RTK) inhibitor with IC₅₀s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively . Sitravatinib shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment .

HY-161101

MG degrader 1	PROTACs IKZF Family	Cancer
MG degrader 1 (Compd E14) is a PROTAC degrader of IKZF3, GSPT1, and GSPT2 with an EC₅₀ value of 1.385 nM in MM.1S cells .

HY-16961A

Sitravatinib malate MGCD516 malate; MG-516 malate	VEGFR c-Kit FLT3 Discoidin Domain Receptor Trk Receptor	Inflammation/Immunology Cancer
Sitravatinib malate (MGCD516 malate) is an orally bioavailable receptor tyrosine kinase (RTK) inhibitor with IC₅₀s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively . Sitravatinib malate shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment .

HY-13259G

MG-132 Z-Leu-Leu-Leu-al	Proteasome Autophagy Apoptosis	Cancer
MG-132 (GMP) (Z-Leu-Leu-Leu-al (GMP)) is MG-132 (HY-13259) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC₅₀s of 100 nM and 1.2 μM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis .

HY-W134005

Mg(Ⅱ)-EDTA disodium tetrahydrate Ethylenediaminetetraacetic acid magnesium disodium tetrahydrate	Phosphatase	Others
Mg(Ⅱ)-EDTA disodium tetrahydrate is a reversible non-covalent activator of fructose diphosphatase (K_m=0.9 μM). Mg(Ⅱ)-EDTA disodium tetrahydrate synergistically activates fructose diphosphatase with free Mg ²⁺, promotes the hydrolysis of fructose-1,6-bisphosphate at pH≤8, and plays a role in enhancing the activity of key enzymes in gluconeogenesis .

HY-18964

MG-101 10+ Cited Publications Calpain inhibitor I; Ac-LLnL-CHO; ALLN	Proteasome Apoptosis	Cancer
MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with K_is of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer .

HY-108551

MG-262 1 Publications Verification Z-Leu-Leu-LeuB(OH)2; ZL3B	Proteasome VEGFR Apoptosis Reactive Oxygen Species (ROS)	Cardiovascular Disease Inflammation/Immunology Cancer
MG-262 (Z-Leu-Leu-LeuB(OH)2; ZL3B) is a reversible proteasome inhibitor. MG-262 down-regulates VEGF receptor Flt-1. MG-262 inhibits cell growth and induces apoptosis in malignant cells. MG-262 induces reactive oxygen species (ROS). MG-262 can be used for anti-cancer study .

HY-N12224

1-Heptadecanoyl-rac-glycerol MG(17:0/0:0/0:0); 1-Heptadecanoin	NO Synthase	Inflammation/Immunology
1-Heptadecanoyl-rac-glycerol (1-Heptadecanoin) is a glyceride compound with anti-inflammatory activity. 1-Heptadecanoyl-rac-glycerol inhibits the occurrence of inflammation by suppressing the expression of inducible nitric oxide synthase (iNOS) related to inflammation. 1-Heptadecanoyl-rac-glycerol can be used for research on diseases related to inflammation .

HY-18964G

MG-101 Calpain inhibitor I; Ac-LLnL-CHO; ALLN	Proteasome Apoptosis	Cancer
MG-101 (GMP) (Calpain inhibitor I (GMP)) is MG-101 (HY-18964) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with K_is of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer .

HY-170471

1-Arachidoyl-rac-glycerol α-Monoarachin; 2,3-Dihydroxypropyl icosanoate; MG(20:0/0:0/0:0)	Biochemical Assay Reagents	Metabolic Disease
1-Arachidoyl-rac-glycerol (α-Monoarachin) is a monoacylglycerol that contains Arachidic acid (HY-W004260) .

HY-174755

Human CCL27 mRNA	mRNA	Inflammation/Immunology
Human CCL27 mRNA encodes the human C-C motif chemokine ligand 27 (CCL27) protein, a chemotactic for skin-associated memory T lymphocytes. CCL27 also plays a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10).

HY-174776

Human BAX mRNA	mRNA	Cancer
Human BAX mRNA encodes the human BCL2 associated X, apoptosis regulator (BAX) protein, a member of the BCL2 protein family. BAX forms a heterodimer with BCL2, and functions as an apoptotic activator. It also plays a role in the mitochondrial apoptotic process.

HY-W105884

H-Asp-OH.Mg	Amino Acid Derivatives	Others
H-Asp-OH.Mg is an aspartic acid derivative .

HY-W588285

3-Methylguanine 3-MG	DNA/RNA Synthesis	Others
3-Methylguanine is a DNA damage product caused by alkylation. 3-Methylguanine is cytotoxic and causes cell death by inhibiting DNA replication. 3-Methylguanine can be used to study the mechanism of DNA damage caused by alkylating agents and its repair pathways .

HY-N15987

C18(Plasm) MG	Biochemical Assay Reagents	Others
C18(Plasm) MG is a glyceride.

HY-13259C

(R)-MG-132 10+ Cited Publications (S,R,S)-(-)-MG-132; Z-Leu-D-Leu-Leu-al	Proteasome	Cancer
(R)-MG-132 ((S,R,S)-(-)-MG-132) is the enantiomer of MG-132. (R)-MG-132 is a proteasome inhibitor with weaker cell cytotoxicity than MG-132 .

HY-135416A

Streptolysin O (≥1000000 units/mg)	Endogenous Metabolite	Infection
Streptolysin O (≥1000000 units/mg) is a ≥1000000 units/mg Streptolysin O (HY-135416). Streptolysin O, a group A streptococcal toxin, is a well-characterized oxygen-labile prototype of a cholesterol-binding bacterial exotoxin. Streptolysin O causes both lysis of cells and cardiotoxicity. Streptolysin O is widely used for the controlled permeabilization of cell membranes. Streptolysin O exists in two forms, a reduced active state and an oxidized reversibly inactive state .

HY-114158A

Pronase E (Activity ≥ 4000 U/mg) 10+ Cited Publications Pronase (Activity ≥ 4000 U/MG)	Others	Others
Pronase E (Activity ≥ 4000 U/mg) is a mixture of proteolytic enzymes that is obtained from Streptomyces griseus and could digest protein into individual amino acids .

HY-N15886

C4 BODIPY 505/515 MG	Fluorescent Dye	Others
C4 BODIPY 505/515 MG is a fluorescently labeled glycerolipid (Ex/Em = 495/503 nm).

HY-P1645A

Papain (1.5-10 units/mg)	Cathepsin	Others
Papain (1.5-10 units/mg) is a plant proteolytic enzyme in the cysteine protease family, widely used in food, medicine and other fields .

HY-N15900

C11 BODIPY 505/515 MG	Fluorescent Dye	Others
C11 BODIPY 505/515 MG is a fluorescently labeled glycerolipid (Ex/Em = 495/503 nm).

HY-P1645B

Papain (lyophilized powder, ≥10 units/mg protein)	Cathepsin	Others
Papain (lyophilized powder, ≥10 units/mg protein) is a cysteine protease of the peptidase C1 family, which is used in food, pharmaceutical, textile, and cosmetic industries .

HY-129046A

RNase A (10mg/mL, DNase free) 3 Publications Verification	DNA/RNA Synthesis	Others
RNase A (10mg/mL, DNase free) is a ribonuclease used to catalyze RNA degradation without containing DNase. RNase A is often employed in cell cycle assay .

HY-168969

AA-BR-157	PROTACs	Cancer
AA-BR-157 is a PROTAC degrader for metallothionein 2A (MT2A) with a DC₅₀ of 190 nM. AA-BR-157 downregulates the cytoskeleton and cell motility regulating protein DIAPH3, inhibits the migration of MDA-MB-231 and U-87 MG. AA-BR-157 regulates the zinc homeostasis in MDA-MB-231 . (Pink: ligand for target protein MT2A ligand 1 (HY-168970); Black: linker (HY-119429); Blue: ligand for VHL E3 ligase (HY-125845))

HY-P10777

ANG1009	Peptide-Drug Conjugates (PDCs)	Cancer
ANG1009 is a BBB-penetrable anticancer agent. ANG1009 is cytotoxic to a variety of tumor cells and can induce cell cycle arrest. ANG1009 can be used in the study of brain cancer .

Cat. No.	Product Name	Type

HY-13259G

MG-132 (GMP)

Z-Leu-Leu-Leu-al (GMP)

Fluorescent Dye

MG-132 (GMP) (Z-Leu-Leu-Leu-al (GMP)) is MG-132 (HY-13259) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC₅₀s of 100 nM and 1.2 μM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis .

HY-18964G

MG-101 (GMP)

Calpain inhibitor I (GMP); Ac-LLnL-CHO (GMP); ALLN (GMP)

Fluorescent Dye

MG-101 (GMP) (Calpain inhibitor I (GMP)) is MG-101 (HY-18964) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with K_is of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer .

Cat. No.	Product Name	Type

HY-W134005

Mg(Ⅱ)-EDTA disodium tetrahydrate Ethylenediaminetetraacetic acid magnesium disodium tetrahydrate	Chelators
Mg(Ⅱ)-EDTA disodium tetrahydrate is a reversible non-covalent activator of fructose diphosphatase (K_m=0.9 μM). Mg(Ⅱ)-EDTA disodium tetrahydrate synergistically activates fructose diphosphatase with free Mg ²⁺, promotes the hydrolysis of fructose-1,6-bisphosphate at pH≤8, and plays a role in enhancing the activity of key enzymes in gluconeogenesis .

HY-NP002

BSA Standard Solution (5mg/mL)	Native Proteins
BSA Standard Solution can reduce PCR inhibition .

HY-P1956A

Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)

HSA (Cell culture grade, Endotoxin<0.125 EU/MG)

Native Proteins

Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, iNOS, and peroxynitrite (ONOO ⁻) in the vascular wall, contributing to the reduction of blood pressure .

HY-13259G

MG-132 (GMP)

Z-Leu-Leu-Leu-al (GMP)

Biochemical Assay Reagents

HY-18964G

MG-101 (GMP)

Calpain inhibitor I (GMP); Ac-LLnL-CHO (GMP); ALLN (GMP)

Biochemical Assay Reagents

Cat. No.	Product Name	Target	Research Area

HY-W105884

H-Asp-OH.Mg	Amino Acid Derivatives	Others
H-Asp-OH.Mg is an aspartic acid derivative .

HY-P11315

MG1 peptide	Biochemical Assay Reagents	Neurological Disease
MG1 peptide is a M1 Microglia-targeting peptide. MG1 peptide can conjugate to anoparticles, crossing the BBB to precisely M1 microglia recognition and achieving controlled release and specific accumulation of drugs through intelligent molecular switching. MG1 peptide can be used for drug delivery for ischemic stroke research .

HY-P10777

ANG1009	Peptide-Drug Conjugates (PDCs)	Cancer
ANG1009 is a BBB-penetrable anticancer agent. ANG1009 is cytotoxic to a variety of tumor cells and can induce cell cycle arrest. ANG1009 can be used in the study of brain cancer .

HY-16532

Zoptarelin doxorubicin AEZS-108; AN-152	Peptide-Drug Conjugates (PDCs) GnRH Receptor	Cancer
Zoptarelin doxorubicin (AEZS-108; AN-152) is a hybrid anticancer agent, containing Zoptarelin and Doxorubicin. Zoptarelin doxorubicin has been used to research targeting tumors expressing LHRH receptors. Zoptarelin doxorubicin abolishes tumor progression and induces remarkable apoptosis in vitro .

Cat. No.	Product Name	Target	Research Area

HY-P990302

Anti-Human/Rat/Fish AChR Antibody (Mab35)	nAChR	Neurological Disease
Anti-Human/Rat/Fish AChR Antibody (Mab35) is an anti-human/rat/fish AChR IgG1 monoclonal antibody. Anti-Human/Rat/Fish AChR Antibody (Mab35) can attack the AChR of neuromuscular junctions. Anti-Human/Rat/Fish AChR Antibody (Mab35) can be used for the construction of myasthenia gravis models .

HY-P991475

MG-1131	Transmembrane Glycoprotein NF-κB IFNAR	Cancer
MG-1131 is a human monoclonal antibody (mAb) targeting TIGIT. MG-1131 activates NF-κB signaling in T cells and enhances NK-mediated tumor killing activity in a PVR-dependent manner. MG-1131 blocks TIGIT to increase IFN-γ secretion. MG-1131 can be used in anti-tumor immunity research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P991379

MG1113A	Tissue Factor Pathway Inhibitor (TFPI)	Others
MG1113A is a human monoclonal antibody (mAb) targeting TFPI. MG1113A can be used in Haemophilia research.

HY-P990910

Comekibart MG-K10	Interleukin Related	Inflammation/Immunology
HY-P990910 is an IL4R-targeting IgG4κ type humanized antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .

Species:	Virus (3) Human (6) Bovine (1)
Tag:	His (8) Tag Free (1) Strep (1) Myc (1) GST (1) Flag (1)
Source:	HEK293 (3) E. coli Cell-free (2) Sf9 insect cells (1) E. coli (5)

Cat. No.	Compare	Product Name	Species	Source

HY-P703417

	TRIM72 Protein, Human MG53	Human	E. coli
	TRIM72 Protein, Human is the recombinant human-derived TRIm72, expressed by E. coli , with tag Free labeled tag.

HY-P703418

	TRIM72 Protein, Human (His) MG53	Human	E. coli
	TRIM72 Protein, Human (His) is the recombinant human-derived TRIM72, expressed by E. coli , with His labeled tag. ,

HY-P702378

	MG281 Protein, Mycoplasma genitalium (Cell-Free, His) Uncharacterized protein MG281	Others	E. coli Cell-free
	MG281 Protein, Mycoplasma genitalium (Cell-Free, His) is the recombinant MG281 protein, expressed by E. coli Cell-free, with N-10*His labeled tag.

HY-P74124

	glycoprotein/G Protein, HRSV (HEK293, His) Major surface glycoprotein G; MG; Mature sG; G	Virus	HEK293
	Glycoproteins/G proteins play a key role in infection by attaching viral particles to the host cell membrane through heparan sulfate interactions, thereby initiating infection. It also interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, contributing to immune regulation and promoting infection. glycoprotein/G Protein, HRSV (HEK293, His) is the recombinant Virus-derived glycoprotein/G protein, expressed by HEK293 , with C-His labeled tag.

HY-P703782

	Glycoprotein/G Protein, HRSV (232a.a, HEK293, His) Major surface glycoprotein G; Attachment glycoprotein G; Membrane-bound glycoprotein; MG; G; MG	Virus	HEK293
	Glycoprotein/G Protein, HRSV (232a.a, HEK293, His) is the recombinant virus-derived Glycoprotein/G protein, expressed by HEK293, with N-His tag.

HY-P71550

	ATP5MG Protein, Bovine (Myc, His) ATP5MG; ATP5LATP synthase subunit g; mitochondrial; ATPase subunit g; ATP synthase membrane subunit g	Bovine	E. coli
	ATP5MG Protein, an essential part of mitochondrial membrane ATP synthase (Complex V), facilitates ATP generation from ADP using the proton gradient established by respiratory chain electron transport complexes. Positioned within the F(0) domain as a minor subunit alongside subunit a, ATP5MG collaborates with various subunits in the overall F-type ATPase complex, including CF(1) and CF(0), to ensure efficient ATP synthesis. ATP5MG Protein, Bovine (Myc, His) is the recombinant bovine-derived ATP5MG protein, expressed by E. coli , with N-His, C-Myc labeled tag.

HY-P704637

	glycoprotein/G Protein, HRSV (His) Major surface glycoprotein G; MG; Mature sG; G	Virus	E. coli
	Glycoproteins/G proteins play a key role in infection by attaching viral particles to the host cell membrane through heparan sulfate interactions, thereby initiating infection. It also interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, contributing to immune regulation and promoting infection. glycoprotein/G Protein, HRSV (His) is the recombinant virus-derived glycoprotein/G protein, expressed by E. coli, with N-His labeled tag.

HY-P702374

	Mucolipin-1/MCOLN1 Protein, Human (Cell-Free, His) Mucolipin-1; MG-2; Mucolipidin; Transient receptor potential channel mucolipin 1; TRPML1	Human	E. coli Cell-free
	The TRPML1 protein is a nonselective cation channel that regulates membrane trafficking and metal homeostasis. It promotes the release of Ca(2+) in late endosomes and lysosomes, affecting organelle fusion, exocytosis and autophagy. Mucolipin-1/MCOLN1 Protein, Human (Cell-Free, His) is the recombinant human-derived MCOLN1 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.

HY-P705508

	VCP Protein, Human (sf9, GST) Transitional Endoplasmic Reticulum ATPase; TER ATPase; 15S MG(2+)-ATPase p97 Subunit; Valosin-Containing Protein; VCP	Human	Sf9 insect cells
	VCP proteins are indispensable for Golgi stack dynamics, coordinating fragmentation during mitosis and postmitotic reorganization. It actively promotes the formation of the transitional endoplasmic reticulum (tER), enables ATP-dependent vesicle budding, and enables membrane transfer to the Golgi apparatus. VCP Protein, Human (sf9, GST) is the recombinant human-derived VCP protein, expressed by Sf9 insect cells , with N-GST labeled tag.

HY-P701383

	Mucolipin-1/MCOLN1 Protein, Human (HEK293, StrepⅡ, FLAG) MCOLN1 (ML4, TRPML1); Mucolipin-1; MG-2; Mucolipidin; Transient receptor potential channel mucolipin 1 (TRPML1)	Human	HEK293
	The TRPML1 protein is a nonselective cation channel that regulates membrane trafficking and metal homeostasis. It promotes the release of Ca(2+) in late endosomes and lysosomes, affecting organelle fusion, exocytosis and autophagy. Mucolipin-1/MCOLN1 Protein, Human (HEK293, StrepⅡ, FLAG) is the recombinant human-derived TRPML1 protein, expressed by HEK293 , with N-Strep, C-Flag labeled tag.

HY-P71022

	PP1MG Protein, Human (His) Protein Phosphatase 1G; Protein Phosphatase 1C; Protein Phosphatase 2C Isoform Gamma; PP2C-Gamma; Protein Phosphatase Magnesium-Dependent 1 Gamma; PPM1G; PPM1C	Human	E. coli
	PP1MG Protein, a member of PPM family of serine/threonine phosphatases, has an important role in controlling cell cycle progression. PP1MG Proteinregulates the phosphorylation of SRSF3 in hepatocellular carcinoma (HCC) and contributes to the proliferation, invasion, and metastasis of HCC. PP1MG Protein forms a distinct holoenzyme complex with the PP2A regulatory subunit B56δ. B56δ‐PPM1G dephosphorylates α‐catenin at serine 641, which is necessary for the appropriate assembly of adherens junctions and the prevention of aberrant cell migration. PP1MG Protein, Human (His) is the recombinant human-derived PP1MG protein, expressed by E. coli , with C-6*His labeled tag.

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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81797

	SAMHD1 Antibody (YA1542) SAMHD1; AGS5; CHBL2; DCIP; HDDC1; MOP-5; MOP5; SBBI88; MG11	WB, IHC-P, ICC/IF, FC	Human
	SAMHD1 Antibody (YA1542) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SAMHD1.

HY-P82630

	VCP Antibody (YA2375) 15S MG(2+) ATPase p97 subunit; ALS14; ATPase p97; CDC48; IBMPFD; p97; TER ATPase; TERA; VCP; Yeast Cdc48p homolog	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	VCP Antibody (YA2375) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VCP.

HY-P81260A

	beta 2 Microglobulin Antibody (YA935) B2MG; Beta 2 microglobin; Beta 2 microglobulin; Beta-2-microglobulin form pI 5.3; CDABP0092; Hdcma22p	WB, IP	Human, Mouse, Rat
	beta 2 Microglobulin Antibody (YA935) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to beta 2 Microglobulin.

HY-P86974

	Mucolipin-1 Antibody (YA6667) MCLN1_HUMAN antibody; Mcoln 1 antibody; Mcoln1 antibody; MG 2 antibody; MG-2 antibody; MG2 antibody; ML 4 antibody; ML4 antibody; MLIV antibody; MST080 antibody; MCLN1_HUMAN antibody; Mcoln 1 antibody; Mcoln1 antibody; MG 2 antibody; MG-2 antibody; MG2 antibody; ML 4 antibody; ML4 antibody; MLIV antibody; MST080 antibody; MSTP080 antibody; Mucolipidin antibody; Mucolipin 1 antibody; Mucolipin-1 antibody; Mucolipin1 antibody; TRP ML1 antibody; TRPML1 antibody;	WB, IHC-P	Human, Mouse, Rat
	Mucolipin-1 Antibody (YA6667) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mucolipin-1.

HY-P84810

	Mucin 5B Antibody (YA4507) MG1; MUC5; MUC9; MUC-5B	IHC-P, FC, ELISA	Human
	Mucin 5B Antibody (YA4507) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Mucin 5B.

HY-P81260

	beta 2 Microglobulin Antibody (YA934) B2MG; Beta 2 microglobin; Beta 2 microglobulin; Beta-2-microglobulin form pI 5.3; CDABP0092; Hdcma22p	ELISA	Human
	beta 2 Microglobulin Antibody (YA934) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to beta 2 Microglobulin.

HY-P86963

	MPG/AAG Antibody (YA6656) 3 alkyladenine DNA glycosylase antibody; 3-alkyladenine DNA glycosylase antibody; 3-methyladenine DNA glycosidase antibody; 3MG_HUMAN antibody; AAG antibody; ADPG antibody; Alkyladenine DNA glycosylase antibody; anpg antibody; APNG antibody; CRA36.1 antibody; 3 alkyladenine DNA glycosylase antibody; 3-alkyladenine DNA glycosylase antibody; 3-methyladenine DNA glycosidase antibody; 3MG_HUMAN antibody; AAG antibody; ADPG antibody; Alkyladenine DNA glycosylase antibody; anpg antibody; APNG antibody; CRA36.1 antibody; DNA 3 methyladenine glycosylase antibody; DNA-3-methyladenine glycosylase antibody; MDG antibody; Mid1 antibody; Mpg antibody; N methylpurine DNA glycosirase antibody; N methylpurine DNA glycosylase antibody; N-methylpurine-DNA glycosylase antibody; PIG11 antibody; PIG16 antibody; Proliferation inducing protein 11 antibody; Proliferation inducing protein 16 antibody;	WB, IHC-P, ICC/IF, FC	Human
	MPG/AAG Antibody (YA6656) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MPG/AAG.

HY-P86752

	beta 2 Microglobulin Antibody (YA6444) B2M; beta 2 microglobulin precursor; beta-2 Microglobulin; beta chain of mhc class 1 proteins; Hdcma22p; B2MG_HUMAN; beta 2 microglobin; beta 2 microglobulin precursor; beta chain of mhc class 1 proteins; beta chain of MHC class I molecules; beta-2-microglobulin form pI 5.3; CDABP0092.	WB	Human
	beta 2 Microglobulin Antibody (YA6444) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to beta 2 Microglobulin.

HY-P87013

	PPM1E Antibody (YA6706) Ca(2+)/calmodulin-dependent protein kinase phosphatase N antibody; CaMKN antibody; CaMKP-N antibody; CaMKP-nucleus antibody; KIAA1072 antibody; Nuclear calmodulin dependent protein kinase phosphatase antibody; Partner of PIX 1 antibody; Partner of PIX-alpha antibody; Partner of PIXA antibody; POPX1 antibody; Ca(2+)/calmodulin-dependent protein kinase phosphatase N antibody; CaMKN antibody; CaMKP-N antibody; CaMKP-nucleus antibody; KIAA1072 antibody; Nuclear calmodulin dependent protein kinase phosphatase antibody; Partner of PIX 1 antibody; Partner of PIX-alpha antibody; Partner of PIXA antibody; POPX1 antibody; PP2CH antibody; Ppm1e antibody; PPM1E_HUMAN antibody; Protein phosphatase 1E antibody; Protein phosphatase MG2+/Mn2+ dependent 1E antibody;	WB	Human
	PPM1E Antibody (YA6706) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPM1E.

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Cat. No.	Product Name		Classification

HY-153627

GK13S		Alkynes
G13KS is a deubiquitinase UCHL1 ligand and inhibitor. G13KS inhibits recombinant and cellular UCHL1. G13KS reduces levels of monoubiquitin in human glioblastoma cells . GK13S is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-153808B

Complete Freund's adjuvant (CFA, 1 mg/ml)		Adjuvant
Complete Freund's adjuvant (CFA, 1 mg/ml) is an immunoadjuvant emulsified with antigen that can enhance an animal's immune response to an antigen. Complete Freund's adjuvant (CFA, 1 mg/ml) is also an inducer of the Th1 immune response and a ligand of TLRs. Complete Freund's adjuvant (CFA, 1 mg/ml) contains heat-killed inactive tuberculosis bacilli and consists of a paraffin oil-in-water emulsion. Complete Freund's adjuvant (CFA, 1 mg/ml) stimulates a strong and durable immune response and can be used to induce rheumatoid arthritis in rats, and more .

HY-159747

Aluminum hydroxide adjuvant aluminum : 4~6 mg/mL		Adjuvant
Aluminum hydroxide adjuvant (aluminum : 4~6 mg/mL) is a micron level water-based aluminum hydroxide adjuvant. The aluminum content is 4 - 6 mg/ml. It has a strong adsorption capacity for negatively charged antigens, a significant sustained-release effect, no stress response, high safety, and can effectively induce immune responses in the body. It is suitable for various veterinary vaccines, including inactivated vaccines or gene-engineered subunit vaccines for bacterial and viral diseases of livestock and poultry.

HY-RS08396

MGAM Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
MGAM Human Pre-designed siRNA Set A contains three designed siRNAs for MGAM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-174755

Human CCL27 mRNA		mRNA
Human CCL27 mRNA encodes the human C-C motif chemokine ligand 27 (CCL27) protein, a chemotactic for skin-associated memory T lymphocytes. CCL27 also plays a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10).

HY-174776

Human BAX mRNA		mRNA
Human BAX mRNA encodes the human BCL2 associated X, apoptosis regulator (BAX) protein, a member of the BCL2 protein family. BAX forms a heterodimer with BCL2, and functions as an apoptotic activator. It also plays a role in the mitochondrial apoptotic process.

HY-RS19051

Atp5mg Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Atp5mg Mouse Pre-designed siRNA Set A contains three designed siRNAs for Atp5mg gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS25541

Atp5mg Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Atp5mg Rat Pre-designed siRNA Set A contains three designed siRNAs for Atp5mg gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01210

ATP5MG Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ATP5MG Human Pre-designed siRNA Set A contains three designed siRNAs for ATP5MG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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