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Results for "

DAP

" in MedChemExpress (MCE) Product Catalog:

75

Inhibitors & Agonists

4

Fluorescent Dye

6

Biochemical Assay Reagents

27

Peptides

13

Recombinant Proteins

12

Antibodies

7

Click Chemistry

12

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-78932A

    ADC Linker Cancer
    Dap-NE hydrochloride is a dipeptide hydrochloride and a cleavable ADC Linker.Dap-NE hydrochloride can be used to connect Antibody and toxin molecules (Cytotoxin) to synthesize Antibody-Drug Conjugates (ADCs) .
    Dap-NE hydrochloride
  • HY-78932

    ADC Payload Cancer
    Dap-NE is an intermediate reagent in the synthesis of the ADC toxin Monomethyl auristatin E (HY-15162) .
    Dap-NE
  • HY-78932G

    ADC Linker Cancer
    Dap-NE hydrochloride (GMP) is Dap-NE hydrochloride (HY-78932A) produced by using GMP guidelines. Dap-NE hydrochloride is an intermediate used in the synthesis of antibody-drug conjugates (ADCs) .
    Dap-NE hydrochloride
  • HY-121634

    Polo-like Kinase (PLK) Others
    DAP-81 is an inhibitory agent targeting Polo-like kinases (Plks), a class of evolutionarily conserved serine/threonine kinases. DAP-81 dose-dependently increases the number of monopolar spindles in treated cells. High-resolution live-cell microscopy revealed that Plk activity is required for the assembly and maintenance of bipolar mitotic spindles. Plk inhibition destabilizes centromeric microtubules while stabilizing other spindle microtubules, leading to the formation of monopolar spindles. Further testing of compounds based on "privileged scaffolds" such as the DAP scaffold may lead to the discovery of new cell division probes and anti-microtubule agents.
    DAP-81
  • HY-RS16934

    Small Interfering RNA (siRNA) Others

    Dap Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dap gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Dap Mouse Pre-designed siRNA Set A
    Dap Mouse Pre-designed siRNA Set A
  • HY-RS03525

    Small Interfering RNA (siRNA) Others

    DAP Human Pre-designed siRNA Set A contains three designed siRNAs for DAP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    DAP Human Pre-designed siRNA Set A
    DAP Human Pre-designed siRNA Set A
  • HY-RS23377

    Small Interfering RNA (siRNA) Others

    Dap Rat Pre-designed siRNA Set A contains three designed siRNAs for Dap gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Dap Rat Pre-designed siRNA Set A
    Dap Rat Pre-designed siRNA Set A
  • HY-RS21319

    Small Interfering RNA (siRNA) Others

    Dap3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dap3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Dap3 Mouse Pre-designed siRNA Set A
    Dap3 Mouse Pre-designed siRNA Set A
  • HY-RS03526

    Small Interfering RNA (siRNA) Others

    DAP3 Human Pre-designed siRNA Set A contains three designed siRNAs for DAP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    DAP3 Human Pre-designed siRNA Set A
    DAP3 Human Pre-designed siRNA Set A
  • HY-RS27838

    Small Interfering RNA (siRNA) Others
    Dap3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Dap3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Dap3 Rat Pre-designed siRNA Set A
    Dap3 Rat Pre-designed siRNA Set A
  • HY-107719

    iGluR Neurological Disease
    D-AP7 is a specific NMDA receptor antagonist with inhibitory activity against epileptiform activity. D-AP7 attenuated neuronal activation in spot activity by reducing the duration and number of exogenously induced bursts. D-AP7 also increased the amplitude of secondary action potentials, which may restore neuronal activity in some epileptiform bursts. D-AP7 showed anxiogenic effects and impaired memory consolidation in passive avoidance learning .
    D-AP7
  • HY-100714A
    D-AP5
    15+ Cited Publications

    D-APV; D-2-Amino-5-phosphonovaleric acid

    iGluR Neurological Disease
    D-AP5 (D-APV) is a selective and competitive NMDA receptor antagonist with a Kd of 1.4 μM. D-AP5 (D-APV) inhibits the glutamate binding site of NMDA receptors .
    D-AP5
  • HY-100781

    D-APB; D-2-Amino-4-phosphonobutyric acid

    iGluR Neurological Disease
    D-AP4 (D-APB; D-2-Amino-4-phosphonobutyric acid), a phosphono analogue of glutamate, is an NMDA broad spectrum excitatory amino acid receptor antagonist. D-AP4 also is an agonist for a quisqualate-sensitized AP6 site in hippocampus. D-AP4 inhibits AMPA receptor-stimulated 57Co 2+ influx in cultured cerebellar granule cells (IC50 ≥ 100 μM) .
    D-AP4
  • HY-P1070

    DAP amide, human

    Amylin Receptor Metabolic Disease
    Amylin, amide, human, a 37-amino acid polypeptide, is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. Amylin, amide, human inhibits glucagon secretion, delays gastric emptying, and acts as a satiety agent .
    Amylin, amide, human
  • HY-P1070A

    DAP amide, human TFA

    Amylin Receptor Metabolic Disease
    Amylin, amide, human TFA, a 37-amino acid polypeptide, is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. Amylin, amide, human TFA inhibits glucagon secretion, delays gastric emptying, and acts as a satiety agent .
    Amylin, amide, human TFA
  • HY-164170

    pm-DAP

    Drug Intermediate Others
    Photocaged DAP (pm-DAP) is a protected version of 2,3-Diaminopropionic acid (DAP) (HY-W013673). Photocaged DAP can produce 2,3-Diaminopropionic acid after photodeprotection. Photocaged DAP can be used as an intermediate to capture biosynthetic acylase .
    Photocaged DAP
  • HY-P5523

    NOD-like Receptor (NLR) Endocrinology
    iE-DAP is a Nod1 agonist. Nod1 recognition of iE-DAP can activate the NF-κB pathway, leading to an inflammatory cytokine response. iE-DAP can be used for the research of maternal-fetal inflammation and preterm labor .
    iE-DAP
  • HY-P5523A

    NOD-like Receptor (NLR) Endocrinology
    iE-DAP dihydrochloride is a Nod1 agonist. Nod1 recognition of iE-DAP dihydrochloride can activate the NF-κB pathway, leading to an inflammatory cytokine response. iE-DAP dihydrochloride can be used for the research of maternal-fetal inflammation and preterm labor .
    iE-DAP dihydrochloride
  • HY-145800

    pm-DAP TFA

    Drug Intermediate Others
    Photocaged DAP (pm-DAP) TFA is a protected version of 2,3-Diaminopropionic acid (DAP) (HY-W013673). Photocaged DAP TFA can produce 2,3-Diaminopropionic acid after photodeprotection. Photocaged DAP TFA can be used as an intermediate to capture biosynthetic acylase .
    Photocaged DAP TFA
  • HY-78931G

    ADC Linker Cancer
    Boc-Dap-NE (GMP) is Boc-Dap-NE (HY-78931) produced by using GMP guidelines. Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
    Boc-Dap-NE
  • HY-W008325

    Biochemical Assay Reagents Drug Intermediate Others
    Boc-L-Dap-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Boc-L-Dap-OH is also an intermediate that can be used in the synthesis of other compounds .
    Boc-L-Dap-OH
  • HY-W010962

    Amino Acid Derivatives Others
    Fmoc-Dap(Alloc)-OH is an alanine derivative .
    Fmoc-Dap(Alloc)-OH
  • HY-W109214

    Amino Acid Derivatives Others
    Fmoc-L-Dap(Boc,Me)-OH is a derivative of amino acid with protecting groups. Fmoc-L-Dap(Boc,Me)-OH can be used for synthesis of diaminopropionic acid containing peptide .
    Fmoc-L-Dap(Boc,Me)-OH
  • HY-143700

    Liposome Neurological Disease
    18:0 DAP can be used to formulate lipid nanoparticles (LNPs), which mRNA is encapsulated in their core .
    18:0 DAP
  • HY-144022

    Liposome Others
    16:0 DAP is a cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery .
    16:0 DAP
  • HY-160795

    ADC Linker Cancer
    Boc-NMeVal-Val-Dil-Dap is a linker, that can be used for ADC synthesis.
    Boc-NMeVal-Val-Dil-Dap
  • HY-154981

    ADC Linker Cancer
    Mal-L-Dap(Boc)-Osu is an ADC Linker, and can be used for synthesis of ADCs .
    Mal-L-Dap(Boc)-OSu
  • HY-78931F

    Drug Intermediate Cancer
    (R,S,S,S,R)-Boc-Dap-NE is an isomer of the dipeptide Boc-Dap-NE (HY-78931). Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
    (R,S,S,S,R)-Boc-Dap-NE
  • HY-78931C

    Drug Intermediate Cancer
    (S,S,R,S,R)-Boc-Dap-NE is an isomer of the dipeptide Boc-Dap-NE (HY-78931). Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
    (S,S,R,S,R)-Boc-Dap-NE
  • HY-78931E

    Drug Intermediate Cancer
    (R,S,R,S,R)-Boc-Dap-NE is an isomer of the dipeptide Boc-Dap-NE (HY-78931). Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
    (R,S,R,S,R)-Boc-Dap-NE
  • HY-151640

    ADC Linker Others
    Fmoc-DAP-N3 is a click chemistry reagent containing an azide group. Fmoc-DAP-N3 is a short, linear spacer molecule with Fmoc protected amino function. Fmoc-DAP-N3 can be used in click conjugation and amid bond formation either with small molecules or for bioconjugation with proteins and antibodies . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-DAP-N3
  • HY-144020

    Liposome Others
    14:0 DAP (1,2-dimyristoyl-3-dimethylammonium-propane ) is a cationic lipid that can be used for drug delivery .
    14:0 DAP
  • HY-151780

    ADC Linker Others
    Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Dap(Pentynoyl)-OH serves as an amino acid building block for introducing alkyne functions into peptide sequences by standard Fmoc/tBu protocols. The alkyne residue can be engaged for copper catalyzed click reaction with organic azides or with tetrazines for copper-free conjugations . Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Fmoc-L-Dap(Pentynoyl)-OH
  • HY-78931B

    Drug Intermediate Cancer
    (S,S,S,S,R)-Boc-Dap-NE is the inactive isomer of Boc-Dap-NE (HY-78931), and can be used as an experimental control. Boc-Dap-NE, is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
    (S,S,S,S,R)-Boc-Dap-NE
  • HY-78931A

    Drug Intermediate Cancer
    (R,S,S,R,S)-Boc-Dap-NE is the inactive isomer of Boc-Dap-NE (HY-78931), and can be used as an experimental control. Boc-Dap-NE, is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
    (R,S,S,R,S)-Boc-Dap-NE
  • HY-P1274

    Potassium Channel Inflammation/Immunology
    ShK-Dap22 is a potent Kv1.3-specific immunosuppressive Polypeptide. ShK-Dap22 is a selective Kv1.3 channel blocker with IC50s of 23 pM, 1.8 nM, 10.5 nM, 37 nM, and 39 nM for mKv1.3, mKv1.1, hKv1.6, mKv1.4, and rKv1.2 channels, respectively .
    ShK-Dap22
  • HY-130961

    ADC Linker Cancer
    Boc-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
    Boc-Val-Dil-Dap-OH
  • HY-W010922

    Amino Acid Derivatives Others
    Fmoc-Dap(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bicyclic peptide tachykinin NK2 antagonists .
    Fmoc-Dap(Boc)-OH
  • HY-164867

    Amino Acid Derivatives Others
    Fmoc-L-Dap(NBSD)-OH is a benzodiazole amino acid that can be used as a building block for constructing background-free peptide probes for fluorescence imaging .
    Fmoc-L-Dap(NBSD)-OH
  • HY-78931

    ADC Linker Cancer
    Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
    Boc-Dap-NE
  • HY-130976

    ADC Linker Cancer
    N-Boc-Val-Dil-Dap-Doe is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
    N-Boc-Val-Dil-Dap-Doe
  • HY-130975

    ADC Linker Cancer
    Boc-Val-Dil-Dap-Phe-OMe is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
    Boc-Val-Dil-Dap-Phe-OMe
  • HY-130956

    ADC Linker Cancer
    Boc-NMe-Val-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
    Boc-NMe-Val-Val-Dil-Dap-OH
  • HY-P5524A

    Lauroyl-γ-D-glutamyl-meso-diaminopimelic acid hydrochloride; γ-D-glutamyl-meso-diaminopimelic acid hydrochloride

    NOD-like Receptor (NLR) Others
    C12-iE-DAP hydrochloride is the hydrochloride salt form of C12-iE-DAP (HY-P5524). C12-iE-DAP hydrochloride is a biologically active peptide that has agonistic effects on NOD1 .
    C12-iE-DAP hydrochloride
  • HY-W046355

    Radionuclide-Drug Conjugates (RDCs) Amino Acid Derivatives Others
    Fmoc-D-Dap(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as DOTA-modified peptides and their metal chelates with cancer diagnostic effects .
    Fmoc-D-Dap(Boc)-OH
  • HY-151715

    ADC Linker Others
    N3-D-Dap(Fmoc)-OH is a click chemistry reagent. N3-D-Dap(Fmoc)-OH can be used as a component for coupling by click reaction and as an orthogonally protected diaminocarboxylic acid derivative . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    N3-D-Dap(Fmoc)-OH
  • HY-W250408

    Drug-Linker Conjugates for ADC Cancer
    Fmoc-NMe-Val-Val-Dil-Dap-OH is an intermediate for preparing drug-linker conjugate MC-MMAF, which can be used for synthesis of ADC molecule .
    Fmoc-NMe-Val-Val-Dil-Dap-OH
  • HY-P3477

    Fluorescent Dye Others
    Mca-PLA-Nva-Dap(Dnp)-AR-NH2 is a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) .
    Mca-PLA-Nva-Dap(Dnp)-AR-NH2
  • HY-151781

    ADC Linker Others
    Fmoc-L-Dap(Poc)-OH is a click chemistry reagent containing an azide group. Amino acid building block suitable for side chain Click conjugation with standard protocols and together with tetrazine linkers in copper-free Click conjugation (Diels-Alder) .
    Fmoc-L-Dap(Poc)-OH
  • HY-P5524

    Lauroyl-γ-D-glutamyl-meso-diaminopimelic acid; γ-D-glutamyl-meso-diaminopimelic acid

    NOD-like Receptor (NLR) Others
    C12-iE-DAP (Lauroyl-γ-D-glutamyl-meso-diaminopimelic acid) is a biological active peptide. (a lauroyl (C12) group to the glutamic residue of iE-DAP , NOD1 agonist)
    C12-iE-DAP

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