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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

CD28 Antibody

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CD28 (15) Apoptosis (1) CD3 (1) CD38 (1) EGFR (1)
By Research Areas:	Cancer (5) Inflammation/Immunology (14) Neurological Disease (4)

Inhibitors & Agonists

Inhibitory Antibodies

Antibodies

Targets Recommended: CD28 ADC Antibody Antibody-Drug Conjugates (ADCs) Antibody-Oligonucleotide Conjugates (AOCs) ADC Linker PROTAC-Linker Conjugates for PAC

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990136

Anti-Monkey/Human CD28 Antibody (CD28.2)	CD28	Inflammation/Immunology
Anti-Monkey/Human CD28 Antibody (CD28.2) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to monkey/human *CD28. Anti-Monkey/Human CD28* Antibody (CD28.2) can block CD28 signaling. Anti-Monkey/Human CD28 Antibody (CD28.2) can be used for the research of immunology .

HY-P99123

Anti-Mouse CD28 Antibody (37.51) 1 Publications Verification	CD28	Inflammation/Immunology
Anti-Mouse CD28 Antibody (37.51) is an agonistic agonistic *CD28*-specific antibody derived from the host Syrian Hamster. Anti-Mouse CD28 Antibody (37.51) partially prevents lethal graft-versus-hostdisease (GVHD) by selective depletion of alloreactive T cells in mice .

HY-P990865

*Anti-CD28* Antibody (9.3)**	CD28	Inflammation/Immunology
Anti-CD28 Antibody (9.3) is an anti-human *CD28* IgG2a monoclonal antibody. Anti-CD28 Antibody (9.3) can activate T cells. Anti-CD28 Antibody (9.3) can be used for research on immunology. The recommend isotype control of Anti-CD28 Antibody (9.3): Mouse IgG2a kappa, Isotype Control (HY-P99978) .

HY-P99302

Lulizumab Humanized Anti-CD28 Recombinant Antibody	CD28	Inflammation/Immunology
Lulizumab (Humanized Anti-CD28 Recombinant Antibody) is an anti-CD28 domain antibody antagonist. Lulizumab inhibits T-cell activation by selectively targeting the CD28 signal. In a sensitized non-human primate kidney transplantation model, when combined with Carfilzomib (HY-10455), Lulizumab can regulate immune cells and prolong the survival time of the graft .

HY-P990587

FR104	CD28	Inflammation/Immunology
FR104 is a humanized antibody expressed in CHO cells that targets *CD28*. FR104 comprises a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for FR104 can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990803

Anti-Mouse CD28 Antibody (PV-1)	CD28	Inflammation/Immunology Cancer
Anti-Mouse CD28 Antibody (PV-1) is an anti-mouse *CD28* IgG monoclonal antibody. Anti-Mouse CD28 Antibody (PV-1) can activate T cells. Anti-Mouse CD28 Antibody (PV-1) can be used for researches on cancer and immunology such as leukemia. The recommend isotype control of Anti-Mouse CD28 Antibody (PV-1): Armenian hamster IgG, Isotype Control (HY-P990305) .

HY-P990137

Anti-Rat CD28 Antibody (JJ319)	CD28	Neurological Disease Inflammation/Immunology
Anti-Rat CD28 Antibody (JJ319) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to rat *CD28. Anti-Rat CD28* Antibody (JJ319) activates T cells in the presence of T cell receptor-stimulation. Anti-Rat CD28 Antibody (JJ319) can be used for the researches of inflammation and immunology, such as transplantation and neuritis .

HY-P990819

Anti-Rat CD28 Antibody (JJ316)	CD28	Neurological Disease Inflammation/Immunology
Anti-Rat CD28 Antibody (JJ316) is a mouse-derived agonistic IgG1 κ type antibody, targeting to rat *CD28. Anti-Rat CD28* Antibody (JJ316) can induce T cell proliferation. Anti-Rat CD28 Antibody (JJ316) can be used for the researches of inflammation, immunology and neurological disease, such as experimental autoimmune encephalomyelitis (EAE) and graft-versus-host disease (GvHD) .

HY-P990793

Anti-Mouse CD28 Antibody (D665)	CD28	Neurological Disease Inflammation/Immunology Cancer
Anti-Mouse CD28 Antibody (D665) is a mouse-derived agonistic IgG1 κ type antibody, targeting to mouse *CD28. Anti-Mouse CD28* Antibody (D665) induces the activation of T cells. Anti-Mouse CD28 Antibody (D665) can be used for the researches of neurological disease, inflammation, immunology and cancer, such as Parkinson disease (PD), arthritis and graft-versus-host disease (GVHD) .

HY-P99123A

Anti-Mouse CD28 (LALA-PG) Antibody (D665)	CD28	Neurological Disease Inflammation/Immunology Cancer
Anti-Mouse CD28 (LALA-PG) Antibody (D665) is an anti-mouse *CD28* IgG2a monoclonal antibody. Anti-Mouse CD28 (LALA-PG) Antibody (D665) is a chimeric antibody of the original D665 antibody (HY-P990793). Anti-Mouse CD28 (LALA-PG) Antibody (D665) contains the LALA-PG mutation region. Anti-Mouse CD28 Antibody (D665) induces the activation of T cells. Anti-Mouse CD28 Antibody (D665) can be used for research on neurological conditions, inflammation, immunology and cancer, such as Parkinson disease (PD), arthritis and graft-versus-host disease (GVHD).

HY-P991183

SAR-442257	CD28 CD38 CD3	Cancer
SAR442257 is a humanized IgG4-S228P, kappa monoclonal antibody targeting CD38 and *CD28* on multiple myeloma cells and co-stimulates CD3 and *CD28* on T cells .

HY-P9975

Theralizumab TGN1412	CD28	Inflammation/Immunology
Theralizumab (TGN1412) is a humanized lgG4 superagonistic anti-CD28 monoclonal antibody that directly stimulates T cells. Theralizumab can cause cytokine release syndrome (CRS). Theralizumab can be used for the research of rheumatoid arthritis .

HY-P990752

Nezastomig REGN-5678	CD28	Inflammation/Immunology
Nezastomig is an anti-FOLH1/CD28 human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).

HY-P990913

Dalmitamig bsAb7075; REGN-7075	EGFR	Inflammation/Immunology
HY-P990913 is an *EGFR/CD28*-targeting IgG4κ type human antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .

HY-P99293

Galiximab IDEC 114; Anti-Human CD80 Recombinant Antibody	CD28 Apoptosis	Cancer
Galiximab (IDEC-114) is a primatized monoclonal IgG1 antibody targeting CD80. Galiximab variable regions are primatized, and the constant regions are humanized. Galiximab induces antibody-dependent cellular cytotoxicity by blocking *CD80-CD28* binding. Galiximab has antitumor activity and can induce apoptosis in tumor cells. Galiximab can be used in the research of relapsed Hodgkin lymphoma and solid tumors .

HY-102090

B7/CD28 interaction inhibitor 1	CD28	Inflammation/Immunology
B7/CD28 interaction inhibitor 1 (copmound 6b) is a potent B7.1-CD28 interaction inhibitor with an IC₅₀ of 50 nM .

Cat. No.	Product Name	Target	Research Area

HY-P990136

Anti-Monkey/Human CD28 Antibody (CD28.2)	CD28	Inflammation/Immunology
Anti-Monkey/Human CD28 Antibody (CD28.2) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to monkey/human *CD28. Anti-Monkey/Human CD28* Antibody (CD28.2) can block CD28 signaling. Anti-Monkey/Human CD28 Antibody (CD28.2) can be used for the research of immunology .

HY-P99123

Anti-Mouse CD28 Antibody (37.51) 1 Publications Verification	CD28	Inflammation/Immunology
Anti-Mouse CD28 Antibody (37.51) is an agonistic agonistic *CD28*-specific antibody derived from the host Syrian Hamster. Anti-Mouse CD28 Antibody (37.51) partially prevents lethal graft-versus-hostdisease (GVHD) by selective depletion of alloreactive T cells in mice .

HY-P990865

*Anti-CD28* Antibody (9.3)**	CD28	Inflammation/Immunology
Anti-CD28 Antibody (9.3) is an anti-human *CD28* IgG2a monoclonal antibody. Anti-CD28 Antibody (9.3) can activate T cells. Anti-CD28 Antibody (9.3) can be used for research on immunology. The recommend isotype control of Anti-CD28 Antibody (9.3): Mouse IgG2a kappa, Isotype Control (HY-P99978) .

HY-P99302

Lulizumab Humanized Anti-CD28 Recombinant Antibody	CD28	Inflammation/Immunology
Lulizumab (Humanized Anti-CD28 Recombinant Antibody) is an anti-CD28 domain antibody antagonist. Lulizumab inhibits T-cell activation by selectively targeting the CD28 signal. In a sensitized non-human primate kidney transplantation model, when combined with Carfilzomib (HY-10455), Lulizumab can regulate immune cells and prolong the survival time of the graft .

HY-P990587

FR104	CD28	Inflammation/Immunology
FR104 is a humanized antibody expressed in CHO cells that targets *CD28*. FR104 comprises a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for FR104 can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

HY-P990803

Anti-Mouse CD28 Antibody (PV-1)	CD28	Inflammation/Immunology Cancer
Anti-Mouse CD28 Antibody (PV-1) is an anti-mouse *CD28* IgG monoclonal antibody. Anti-Mouse CD28 Antibody (PV-1) can activate T cells. Anti-Mouse CD28 Antibody (PV-1) can be used for researches on cancer and immunology such as leukemia. The recommend isotype control of Anti-Mouse CD28 Antibody (PV-1): Armenian hamster IgG, Isotype Control (HY-P990305) .

HY-P990137

Anti-Rat CD28 Antibody (JJ319)	CD28	Neurological Disease Inflammation/Immunology
Anti-Rat CD28 Antibody (JJ319) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to rat *CD28. Anti-Rat CD28* Antibody (JJ319) activates T cells in the presence of T cell receptor-stimulation. Anti-Rat CD28 Antibody (JJ319) can be used for the researches of inflammation and immunology, such as transplantation and neuritis .

HY-P990819

Anti-Rat CD28 Antibody (JJ316)	CD28	Neurological Disease Inflammation/Immunology
Anti-Rat CD28 Antibody (JJ316) is a mouse-derived agonistic IgG1 κ type antibody, targeting to rat *CD28. Anti-Rat CD28* Antibody (JJ316) can induce T cell proliferation. Anti-Rat CD28 Antibody (JJ316) can be used for the researches of inflammation, immunology and neurological disease, such as experimental autoimmune encephalomyelitis (EAE) and graft-versus-host disease (GvHD) .

HY-P990793

Anti-Mouse CD28 Antibody (D665)	CD28	Neurological Disease Inflammation/Immunology Cancer
Anti-Mouse CD28 Antibody (D665) is a mouse-derived agonistic IgG1 κ type antibody, targeting to mouse *CD28. Anti-Mouse CD28* Antibody (D665) induces the activation of T cells. Anti-Mouse CD28 Antibody (D665) can be used for the researches of neurological disease, inflammation, immunology and cancer, such as Parkinson disease (PD), arthritis and graft-versus-host disease (GVHD) .

HY-P99123A

Anti-Mouse CD28 (LALA-PG) Antibody (D665)	CD28	Neurological Disease Inflammation/Immunology Cancer
Anti-Mouse CD28 (LALA-PG) Antibody (D665) is an anti-mouse *CD28* IgG2a monoclonal antibody. Anti-Mouse CD28 (LALA-PG) Antibody (D665) is a chimeric antibody of the original D665 antibody (HY-P990793). Anti-Mouse CD28 (LALA-PG) Antibody (D665) contains the LALA-PG mutation region. Anti-Mouse CD28 Antibody (D665) induces the activation of T cells. Anti-Mouse CD28 Antibody (D665) can be used for research on neurological conditions, inflammation, immunology and cancer, such as Parkinson disease (PD), arthritis and graft-versus-host disease (GVHD).

HY-P991183

SAR-442257	CD28 CD38 CD3	Cancer
SAR442257 is a humanized IgG4-S228P, kappa monoclonal antibody targeting CD38 and *CD28* on multiple myeloma cells and co-stimulates CD3 and *CD28* on T cells .

HY-P9975

Theralizumab TGN1412	CD28	Inflammation/Immunology
Theralizumab (TGN1412) is a humanized lgG4 superagonistic anti-CD28 monoclonal antibody that directly stimulates T cells. Theralizumab can cause cytokine release syndrome (CRS). Theralizumab can be used for the research of rheumatoid arthritis .

HY-P990752

Nezastomig REGN-5678	CD28	Inflammation/Immunology
Nezastomig is an anti-FOLH1/CD28 human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).

HY-P990913

Dalmitamig bsAb7075; REGN-7075	EGFR	Inflammation/Immunology
HY-P990913 is an *EGFR/CD28*-targeting IgG4κ type human antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .

HY-P99293

Galiximab IDEC 114; Anti-Human CD80 Recombinant Antibody	CD28 Apoptosis	Cancer
Galiximab (IDEC-114) is a primatized monoclonal IgG1 antibody targeting CD80. Galiximab variable regions are primatized, and the constant regions are humanized. Galiximab induces antibody-dependent cellular cytotoxicity by blocking *CD80-CD28* binding. Galiximab has antitumor activity and can induce apoptosis in tumor cells. Galiximab can be used in the research of relapsed Hodgkin lymphoma and solid tumors .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81184

	CD80 Antibody (YA3386) Activation B7-1 antigen; B lymphocyte activation antigen B7; B7; B7-1; B7-1 antigen; BB1; CD28 antigen ligand 1; CD28LG; CD28LG1; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 antigen; CD80 molecule; CD80_HUMAN; Costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; T-lymphocyte activation antigen CD80; CD80_RAT.	WB, IHC-P, FC, ICC/IF	Human, Mouse
	CD80 Antibody (YA3386) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to CD80.

HY-P80609

	CD86 Antibody 1 Publications Verification CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD antigen CD86	WB, IHC-P, ICC/IF, IP, FC	Human, Rat
	CD86 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to CD86.

HY-P81347

	CD28 Antibody (YA1092) CD28; T-cell-specific surface glycoprotein CD28; TP44; CD28	IHC-P	Human
	CD28 Antibody (YA1092) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD28.

HY-P84266

	CD80 Antibody (YA3963) B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1	IHC-P, FC, ELISA	Human, Mouse, Rat, Rabbit
	CD80 Antibody (YA3963) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD80.

HY-P84312

	CD86 Antibody (YA4009) B70; B7-2; LAB72; CD28LG2; MGC34413; CD86	WB, ELISA	Human
	CD86 Antibody (YA4009) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD86.

HY-P86912

	ICOS Antibody (YA6605) Activation inducible lymphocyte immunomediatory molecule Antibody; Activation-inducible lymphocyte immunomediatory molecule Antibody; AILIM Antibody; CD278 Antibody; CD278 antigen Antibody; CD28-related Protein-1 Antibody; CRP1 Antibody; CVID1 Antibody; ICOS Antibody; ICOS_HUMAN Antibody; Activation inducible lymphocyte immunomediatory molecule Antibody; Activation-inducible lymphocyte immunomediatory molecule Antibody; AILIM Antibody; CD278 Antibody; CD278 antigen Antibody; CD28-related Protein-1 Antibody; CRP1 Antibody; CVID1 Antibody; ICOS Antibody; ICOS_HUMAN Antibody; Inducible costimulator Antibody; Inducible T cell co stimulator Antibody; Inducible T-cell costimulator Antibody; MGC39850 Antibody;	WB	Mouse, Rat
	ICOS Antibody (YA6605) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ICOS.

HY-P81668

	CD80 Antibody (YA1413) CD80; CD28LG; CD28LG1; LAB7; T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD antigen CD80	FC, ELISA	Human
	CD80 Antibody (YA1413) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD80.

HY-P85094

	CD80 Antibody (YA4786) CD80; CD28LG; CD28LG1; LAB7; T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD antigen CD80	IHC-P, ICC/IF, ELISA	Human
	CD80 Antibody (YA4786) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD80.

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