Search Result
Results for "
Butyl
" in MedChemExpress (MCE) Product Catalog:
41
Biochemical Assay Reagents
38
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W016599
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- HY-N7377
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Glycosidase
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Metabolic Disease
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Butyl isobutyl phthalate is isolated from the rhizoid of Laminaria japonica. Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor with an IC50 value of 38 μM. Butyl isobutyl phthalate shows a hypoglycemic effect and has the potential for diabetes treatment .
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- HY-107346
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Butyl cyanoacrylate
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Biochemical Assay Reagents
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Others
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Enbucrilate (Butyl cyanoacrylate) is a cyanoacrylate ester that has been used as surgical tissue adhesive.
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- HY-W011187
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- HY-W131135
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Decanoic acid, Butyl ester
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Insecticide
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Others
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Butyl decanoate (Decanoic acid) serves as an effective insect repellent.
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- HY-W127382
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Ricinolic acid Butyl ester
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Biochemical Assay Reagents
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Others
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Butyl Ricinoleate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W099584
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Myristic scid Butyl ester
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Biochemical Assay Reagents
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Others
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Butyl tetradecanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W030286
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- HY-W127377
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Biochemical Assay Reagents
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Others
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Butyl oleateIt is an organic compound belonging to esters. It is formed from the reaction of butanol and oleic acid and has a mild fruity smell. Butyl oleateIt has a variety of applications in the cosmetic and personal care industries, especially as an emollient and conditioning agent in skin and hair care products. Additionally, it is used as a lubricant and solvent in industrial settings.
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- HY-B1431S2
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- HY-W127520
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Biochemical Assay Reagents
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Others
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Butyl n-Octanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W154216
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- HY-B1430
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- HY-W127330
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Biochemical Assay Reagents
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Others
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Butyl Laurate is an ester compound with a fruity odor commonly used as a flavoring agent in the food and beverage industry. In addition, it is used as a solvent, plasticizer or lubricant in various industrial applications. Its unique chemical properties make it an important ingredient in a variety of commercial products, including cosmetics, personal care products and cleaners.
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- HY-W127338
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Biochemical Assay Reagents
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Others
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Butyl Palmitate is an ester compound commonly used as a conditioning, emollient or fragrance in a variety of cosmetic and personal care products. In addition, it can be used as a solvent or lubricant in various industrial applications. Its unique chemical properties make it an important ingredient in a variety of commercial products, including perfumes, lotions and hair care products.
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- HY-100009
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Flufenamic acid Butyl ester; Butyl flufenamate
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COX
Prostaglandin Receptor
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Inflammation/Immunology
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Ufenamate (Flufenamic acid butyl ester) is an anthranilic acid-based anti-inflammatory drug that can be used in the study of skin diseases such as acute and chronic eczema, contact dermatitis, diaper dermatitis, miliary rashes and atopic dermatitis. Ufenamate has a certain photoprotective effect, reduces the degree of skin erythema and swelling in the photoaging model, downregulates the expression level of COX-2 and can promote the healing of mouse skull defects by secreting BMP2 .
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- HY-B1430S
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- HY-B1431
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Butyl parahydroxybenzoate; Butyl paraben; Butyl 4-hydroxybenzoate
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Bacterial
Endogenous Metabolite
DNA/RNA Synthesis
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Infection
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Butylparaben is an organic compound that has proven to be a very successful antimicrobial preservative in cosmetics, can also be used in active molecule suspensions, and as a food flavoring additive .
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- HY-B1431A
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Butyl parahydroxybenzoate sodium; Butyl 4-hydroxybenzoate sodium
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DNA/RNA Synthesis
Bacterial
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Others
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Butylparaben sodium strongly influences the later stages of the spermatogenesis in the testis through the deterioration of hormonal control and/or RNA and protein synthesis .
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- HY-B1431S
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Butyl parahydroxybenzoate-d4; Butyl paraben-d4; Butyl 4-hydroxybenzoate-d4
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Isotope-Labeled Compounds
Bacterial
Endogenous Metabolite
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Infection
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Butylparaben-d4 is the deuterium labeled Butylparaben. Butylparaben is an organic compound, has proven to be a highly successful antimicrobial preservative in cosmetics, also used in medication suspensions, and as a flavoring additive in food.
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- HY-B1431S1
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Butyl parahydroxybenzoate-13C6; Butyl 4-hydroxybenzoate-13C6
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Bacterial
Endogenous Metabolite
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Infection
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Butylparaben- 13C6 is the 13C labeled Butylparaben . Butylparaben is an organic compound, has proven to be a highly successful antimicrobial preservative in cosmetics, also used in medication suspensions, and as a flavoring additive in food.
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- HY-B0861R
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Herbicide
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Others
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Cyhalofop-butyl (Standard) is the analytical standard of Cyhalofop-butyl. This product is intended for research and analytical applications. Cyhalofop-butyl is a post-emergence herbicide. Cyhalofop-butyl inhibits acetyl-coenzyme A carboxylase (ACCase) biosynthesis .
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- HY-76548
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tert-Butyl p-methylbenzoate
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Drug Intermediate
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Others
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tert-Butyl p-Toluate (tert-Butyl p-methylbenzoate) is a synthetic intermediate useful for pharmaceutical synthesis.
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- HY-B0861
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Herbicide
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Others
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Cyhalofop-butyl is a post-emergence herbicide. Cyhalofop-butyl inhibits acetyl-coenzyme A carboxylase (ACCase) biosynthesis .
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- HY-N10016
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Tyrosinase
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Cancer
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Chlorogenic acid butyl ester, a caffeoylquinic acid, is a potent melanogenesis inhibitor. Chlorogenic acid butyl ester inhibits the expression of microphtalmia-associated transcription factor (MITF), tyrosinase, tyrosinerelated protein 1 (TRP-1), and TRP-2. Chlorogenic acid butyl ester also shows antioxidant activity .
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- HY-W014540
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tert-Butyl L-prolinate hydrochloride
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Biochemical Assay Reagents
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L-Proline tert-butyl ester hydrochloride (tert-Butyl L-prolinate hydrochloride) is a biologically active compound that has the activity of inhibiting cysteine and cathepsins, and is therefore widely used in the research and development of protease inhibitors. The characteristics of L-Proline tert-butyl ester hydrochloride make it of great significance in the field of biochemistry.
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- HY-21999
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Tert-Butyl 6-aminohexanoate
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PROTAC Linkers
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Cancer
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tert-Butyl 6-aminocaproate (Tert-butyl 6-aminohexanoate) is a PROTAC linker. tert-Butyl 6-aminocaproate can be used in synthesis PROTAC CARM1/IKZF3 degrader-1 (HY-172368) .
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- HY-W014394
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TRP Channel
Parasite
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Infection
Cardiovascular Disease
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Vanillyl butyl ether is a major contributor to the characteristic flavor and fragrance of vanilla. Vanillyl butyl ether is one of the eco-friendly and nontoxic substances. Vanillyl butyl ether exhibits mutually inhibitory effects on mammalian TRPV1 and TRPM8 channels. Vanillyl butyl ether shows repellency activity against Tribolium castaneum, T. confusum and L. bostrychophila. Vanillyl butyl ether acts as a mild warming agent, providing a warming sensation and enhancing blood circulation .
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- HY-17468S1
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- HY-N11760
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Others
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Others
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3-Butyl-5-hydroxyphthalate is a natural product .
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- HY-22391
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tert-Butyl 2,8-diaminooctanoate
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PROTAC Linkers
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Cancer
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tert-Butyl (7-aminoheptyl)carbamate (tert-Butyl 2,8-diaminooctanoate) is a PROTAC linker. tert-Butyl (7-aminoheptyl)carbamate can be used to synthesis CPD-10 (HY-168660) .
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- HY-W585914S
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Isotope-Labeled Compounds
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Others
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2-(3-Sec-butyl-5-tert-butyl-2-hydroxyphenyl)benzotriazole-d4 is deuterium labeled 2-(3-Sec-butyl-5-tert-butyl-2-hydroxyphenyl)benzotriazole .
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- HY-W355238S
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- HY-W019095
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- HY-106567
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Glucocorticoid Receptor
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Inflammation/Immunology
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Fluocortin butyl ester is a developed corticosteroid compound with no detectable systemic corticosteroid activity when it is used topically. Fluocortin butyl ester appears to be an effective well-tolerated topical steroid useful in the research of perennial rhinitis .
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- HY-B2007R
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Reference Standards
Acetyl-CoA Carboxylase
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Metabolic Disease
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Fluazifop-P-butyl (Standard) is the analytical standard of Fluazifop-P-butyl. This product is intended for research and analytical applications. Fluazifop-P-butyl, a graminicide from arylophenoxypropionate group, is a acetyl-CoA carboxylase (ACCase) inhibitor .
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- HY-W074953
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Biochemical Assay Reagents
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Others
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tert-Butyl Hydrogen Tetradecanedioate is a short linker featuring a carboxylic acid and a tert-butyl ester. Carboxylic acids can be reacted with alcohols or amines, while the tert-butyl ester can be selectively deprotected to allow for reactivity as a carboxylic acid to form esters or amides.
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- HY-W399914
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Biochemical Assay Reagents
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Others
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tert-Butyl methyl adipate is a linker with an methyl ester group and a t-butyl ester. The methyl ester groups can be hydrolyzed, reduced, or substituted under different conditions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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- HY-W174661
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Biochemical Assay Reagents
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Others
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tert-Butyl 6-hydroxyhexanoate is a linker with a hydroxyl group and a t-butyl ester. The hydroxyl group allows for further derivatization or replacement with many other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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- HY-W460072
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Biochemical Assay Reagents
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Others
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tert-Butyl 7-hydroxyheptanoate is a linker with a hydroxyl group and a t-butyl ester. The hydroxyl group allows for further derivatization or replacement with many other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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- HY-Y0373
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- HY-150340
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- HY-N9802
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Apoptosis
Bcl-2 Family
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Cancer
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n-Butyl-β-D-fructofuranoside could be isolated from kangaisan. n-Butyl-β-D-fructofuranoside induces apoptosis through the mitochondrial pathway. n-Butyl-β-D-fructofuranoside can be used for cancer research .
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- HY-W007722A
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- HY-W190921
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Biochemical Assay Reagents
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Others
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t-Butyl 3-(hydroxypropoxyl)-propanoate contains reactive hydroxyl and t-butyl protected carboxyl moieties. The hydroxyl group can react to further derivatize the compound. The t-butyl carbonyl group can be deprotected under acidic conditions.
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- HY-W016155R
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Biochemical Assay Reagents
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Others
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2-Butyl-4-chloro-5-formylimidazole (Standard) is the analytical standard of 2-Butyl-4-chloro-5-formylimidazole. This product is intended for research and analytical applications. 2-Butyl-4-chloro-5-formylimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W248726
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Biochemical Assay Reagents
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Others
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tert-Butyl (6-iodohexyl)carbamate is a six carbon linker containing an iodine group and a t-butyl ester. The iodine (I) acts as a good leaving group for nucleophilic substitution reactions. The t-butyl ester groups can be deprotected under acidic conditions.
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- HY-42904
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Drug Intermediate
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Cancer
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Potassium tert-butyl malonate is an intermediate in the synthesis of malonate monoester potassium salt .
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- HY-132350S
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- HY-170057
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- HY-402939A
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- HY-W248248
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PROTAC Linkers
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Cancer
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tert-Butyl 9-aminononanoate is a PROTAC linker. tert-Butyl 9-aminononanoate can be used in synthesis PROTAC sEH-degrader-1 (HY-159494) .
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- HY-Y1030
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tert-Butyl (S)-2-amino-3-methylbutanoate hydrochloride
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Amino Acid Derivatives
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Others
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tert-Butyl L-valinate hydrochloride is a valine derivative .
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- HY-B0867R
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Herbicide
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Others
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2,4-D Butyl ester (Standard) is the analytical standard of 2,4-D Butyl ester. This product is intended for research and analytical applications. 2,4-D Butyl ester is an organic phenoxy herbicide and used to control woody broad-leaf weeds. 2,4-D butyl ester produces its herbicidal effect by mimicking natural plant growth hormones causing plants to grow too rapidly to survive .
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- HY-W017456S
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- HY-Y0533
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L-Aspartic acid β-tert-Butyl ester; β-tert-Butyl L-aspartate
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Amino Acid Derivatives
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Others
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L-Aspartic acid 4-tert-butyl ester is an aspartic acid derivative .
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- HY-135380R
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Drug Intermediate
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Cardiovascular Disease
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Atorvastatin acetonide tert-butyl ester (Standard) is the analytical standard of Atorvastatin acetonide tert-butyl ester. This product is intended for research and analytical applications. Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .
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- HY-W053801
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- HY-75331
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- HY-167919
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Drug Derivative
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Infection
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1-(1-Adamantyl)-3-butyl-2-thiourea is a compound with antiviral activity, demonstrating efficacy against various viral pathogens; 1-(1-Adamantyl)-3-butyl-2-thiourea serves as a potential therapeutic agent in the treatment of viral infections.
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- HY-W013686
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- HY-W009648
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- HY-130159
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Biochemical Assay Reagents
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Others
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Hydroxy-PEG12-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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- HY-W190808
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Biochemical Assay Reagents
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Others
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Tos-PEG11-t-butyl ester is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
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- HY-W016638
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1-Butyl-1-methylpyrrolidin-1-ium chloride
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Biochemical Assay Reagents
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Others
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1-Butyl-1-methylpyrrolidin-1-ium chloride, also known as BMIM chloride, belongs to the class of ionic liquids and consists of a positively charged pyrrolidine cation and a negatively charged chloride anion. This compound is commonly used as a solvent for various chemical reactions, especially those involving organic compounds and metals. Its unique physical and chemical properties, such as low volatility, high thermal stability, and tunable solubility, make it useful in a range of applications in catalysis, electrochemistry, and separation science. Furthermore, 1-butyl-1-methylpyrrolidin-1-ium chloride may have potential applications as a green solvent in energy storage devices and various industrial processes.
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- HY-168682
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Target Protein Ligand-Linker Conjugates
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Cancer
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Adamantane-Butyl alcohol is a selective and persistent degrader targeting the CDK8-cyclin C complex. Adamantane-Butyl alcohol is the linker for LL-K8-22 (PROTAC CDK8-cyclin C, HY-149209) and HyT .
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- HY-118825
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- HY-14184A
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Endothelin Receptor
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Cardiovascular Disease
Endocrinology
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Macitentan n-butyl analogue is a n-butyl analogue of Macitentan. Macitentan is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).
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- HY-W011338R
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Reference Standards
Aryl Hydrocarbon Receptor
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Cancer
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Benzyl butyl phthalate (Standard) is the analytical standard of Benzyl butyl phthalate. This product is intended for research and analytical applications. Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) .
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- HY-Y1353
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- HY-19496
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Buagafuran; Buagarofuran
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5-HT Receptor
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Neurological Disease
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4-Butyl-alpha-agarofuran (AF 5) is an anxiolytic and antidepressant agent. 4-Butyl-alpha-agarofuran a α-agarofuran derivative that can be isolated from Gharu-wood. 4-Butyl-alpha-agarofuran can be used for the research of neurological disease research .
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- HY-W053842
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Biochemical Assay Reagents
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Others
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tert-Butyl 3-iodopropylcarbamate is a compound with a t-butyl and a terminal iodine. The iodine (I) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-W190761
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Biochemical Assay Reagents
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Others
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Amino-PEG11-t-butyl ester is a click chemistry linker containing an amine and a t-butyl ester moiety. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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- HY-172505
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Biochemical Assay Reagents
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Others
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Mal-PEG12-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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- HY-169393
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- HY-32865
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Bacterial
Drug Intermediate
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Infection
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tert-Butyl 2,2,2-trichloroacetimidate is a tert-butylation reagent. tert-Butyl 2,2,2-trichloroacetimidate achieves mild, nonreversible tert-butylation of alcohols and phenols. tert-Butyl 2,2,2-trichloroacetimidate is used in the synthesis of antimicrobial agents .
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- HY-W010037R
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COX
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Inflammation/Immunology
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2-(tert-Butyl)-4-methoxyphenol (Standard) is the analytical standard of 2-(tert-Butyl)-4-methoxyphenol. This product is intended for research and analytical applications. 2-tert-Butyl-4-methoxyphenol is a major component of Butylhydroxyanisole (BHA) (HY-B1066). 2-tert-Butyl-4-methoxyphenol is an antioxidant agent, that inhibits expression of Cox2 and Tnfa genes upon stimulation with Lipopolysaccharides (HY-D1056). 2-tert-Butyl-4-methoxyphenol exhibits anti-inflammatory activity, combined with 2,6-di-tert-butyl-4-methylphenol (BHT) .
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- HY-W010037
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COX
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Inflammation/Immunology
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2-tert-Butyl-4-methoxyphenol is a major component of Butylhydroxyanisole (BHA) (HY-B1066). 2-tert-Butyl-4-methoxyphenol is an antioxidant agent, that inhibits expression of Cox2 and Tnfa genes upon stimulation with Lipopolysaccharides (HY-D1056). 2-tert-Butyl-4-methoxyphenol exhibits anti-inflammatory activity, combined with 2,6-di-tert-butyl-4-methylphenol (BHT) .
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- HY-151877S
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- HY-76929S
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- HY-128463S
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COX
Reactive Oxygen Species (ROS)
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Metabolic Disease
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N-tert-Butyl-α-phenylnitrone-d14 is the deuterium labeled N-tert-Butyl-α-phenylnitrone . N-tert-Butyl-α-phenylnitrone is a nitrone-based free radical scavenger that forms nitroxide spin adducts. N-tert-Butyl-α-phenylnitrone inhibits COX2 catalytic activity. N-tert-Butyl-α-phenylnitrone has potent ROS scavenging, anti-inflammatory, neuroprotective, anti-aging and anti-diabetic activities, and can penetrate the blood-brain barrier .
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- HY-B2007
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- HY-W283556
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Biochemical Assay Reagents
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Cancer
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DO2A-tert-butyl ester is a bifunctional chelator (BFC) that can be used for the coupling of peptides and radionuclides. DO2A-tert-butyl ester can be used in the development of radionuclide imaging tracers .
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- HY-W011338S
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Aryl Hydrocarbon Receptor
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Cancer
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Benzyl butyl phthalate-d4 is the deuterium labeled Benzyl butyl phthalate . Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) .
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- HY-W014238
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- HY-W010156
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- HY-W009354
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DNA/RNA Synthesis
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Others
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Di-tert-butyl diisopropylphosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W016155
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Biochemical Assay Reagents
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Others
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2-Butyl-4-chloro-5-formylimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-136156
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Pomalidomide-PEG6-butyl iodide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 6-unit PEG linker used in PROTAC technology .
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- HY-128463
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- HY-172717
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Fluorescent Dye
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Others
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TAMRA-PEG4-t-butyl ester is a TAMRA red-fluorescent dye linker, with excitation/emission maximum 553/575 nm, containing a t-butyl protected carboxyl group which can be deprotected under acidic conditions.
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- HY-W042009A
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- HY-B0867
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Herbicide
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Others
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2,4-D Butyl ester is an organic phenoxy herbicide and used to control woody broad-leaf weeds. 2,4-D butyl ester produces its herbicidal effect by mimicking natural plant growth hormones causing plants to grow too rapidly to survive .
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- HY-W052066
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Biochemical Assay Reagents
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Others
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tert-Butyl (3-chloropropyl)carbamate is a compound with a t-butyl and a terminal choloride. The cholorine (Cl) is a good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-153551
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Biochemical Assay Reagents
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Cancer
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HBED-CC-tris(tert-butyl ester) is a derivative of HBED-CC and a bifunctional chelator. HBED-CC-tris(tert-butyl ester) can be used in the research of radiolabeling and compounds for tumor-assisted diagnosis .
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- HY-W010037S
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- HY-W024365S
-
-
- HY-12692
-
|
DO3A tert-Butyl; DO3A-t-Bu-ester
|
Drug Derivative
|
Cancer
|
|
DOTA tert-Butyl ester is a cyclic tosamide benzyl derivative.
|
-
- HY-W007408
-
-
- HY-W013638
-
-
- HY-172643
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl 2-((5-bromopentyl)oxy)acetate is a PROTAC linker. tert-Butyl 2-((5-bromopentyl)oxy)acetate can be used in synthesis ERD-308 (HY-128600) .
|
-
- HY-152906
-
-
- HY-126070
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Butyl cinnamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-114818
-
|
|
Bacterial
|
Infection
|
|
4-(tert-Butyl)-benzhydroxamic Acid is a PqsR antagonist with IC50s of 12.5 μM and 23.6 μM for E. coli and P. aeruginosa, respectively. 4-(tert-Butyl)-benzhydroxamic Acid reduces the production of the virulence factor pyocyanin in P. aeruginosa with an IC50 of 87.2 μM .
|
-
- HY-W024365R
-
|
|
PROTAC Linkers
|
Cancer
|
|
3-tert-Butyl-4-methoxyphenol (Standard) is the analytical standard of 3-tert-Butyl-4-methoxyphenol. This product is intended for research and analytical applications. 3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .
|
-
- HY-W034551
-
|
|
Radionuclide-Drug Conjugates (RDCs)
|
Others
Cancer
|
|
DOTA-tri(t-butyl ester) belongs to the DOTA class of chelating agents. DOTA-tri(t-butyl ester) is a key raw material for synthesizing nanospherical magnetic resonance imaging (MRI) contrast agents, which are used in MR angiography and tumor angiogenesis imaging .
|
-
- HY-W002322
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl 2-(diethoxyphosphoryl)acetate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W451440
-
-
- HY-131266
-
|
|
Drug Metabolite
|
Others
|
|
Febuxostat n-butyl isomer is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM .
|
-
- HY-W001954
-
-
- HY-139265
-
-
- HY-34519
-
|
L-Tyrosine tert-Butyl ester; tert-Butyl (S)-2-amino-3-(4-hydroxyphenyl)propanoate; tert-Butyl L-tyrosinate
|
Amino Acid Derivatives
|
Others
|
|
(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid tert-butyl ester is a tyrosine derivative .
|
-
- HY-44141
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl 3-(2-iodoethoxy)propanoate is a PROTAC linker, which refers to the PEG composition. tert-Butyl 3-(2-iodoethoxy)propanoate can be used in the synthesis of PROTAC FAK degrader 1 (HY-119932) .
|
-
- HY-W011657
-
|
|
Others
|
Others
|
|
tert-Butyl 4-(bromomethyl)benzoate is a synthetic intermediate useful for compound synthesis .
|
-
- HY-153551A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
HBED-CC-tris(tert-butyl ester) TFA is a derivative of HBED-CC and a bifunctional chelator. HBED-CC-tris(tert-butyl ester) TFA can be used in the research of radiolabeling and compounds for tumor-assisted diagnosis .
|
-
- HY-60280
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Di-tert-butyl iminodicarboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W127701
-
|
1-Butyl-1-methylpiperidinium bis(trifluoromethylsulfonyl)imide
|
Biochemical Assay Reagents
|
Others
|
|
[Bmpip][NTf2] is composed of 1-butyl-1-methylimidazolium cation and bis(trifluoromethylsulfonyl)imide anion.
|
-
![[Bmpip][NTf2]](//file.medchemexpress.eu/product_pic/hy-w127701.gif)
- HY-W030321
-
-
- HY-N9702
-
|
|
Others
|
Others
|
|
n-Butyl-β-D-fructopyranoside is a fructopyranoside can be isolated from Myrica rubra (Myricaceae) .
|
-
- HY-34346
-
|
[[[Hydrazino]carbonyl]methyl]carbamic acid tert-Butyl ester; tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate; tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate
|
Amino Acid Derivatives
|
Others
|
|
tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate is a Glycine (HY-Y0966) derivative .
|
-
- HY-W011338
-
|
|
Aryl Hydrocarbon Receptor
|
Cancer
|
|
Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) .
|
-
- HY-W012482
-
|
|
Fluorescent Dye
|
Others
|
|
5-(tert-Butyl)isobenzofuran-1,3-dione is a intermediate and dye. 5-(tert-Butyl)isobenzofuran-1,3-dione has a synonym of 4-tert-Butylphthalic Anhydride .
|
-
- HY-Y1778
-
|
|
Fluorescent Dye
|
Others
|
|
N-(Diphenylmethylene)glycine tert-butyl ester is a dye, also as the raw material and intermediate for organic syntheses .
|
-
- HY-132088
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W030771
-
-
- HY-130715
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl 11-aminoundecanoate (compound 6b) is a PROTAC linker, which refers to the PEG composition. tert-Butyl 11-aminoundecanoate can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins .
|
-
- HY-W006923
-
-
- HY-W010937
-
|
BMIM-TFSI; BMI-TFSI
|
HIV
HIV Integrase
|
Infection
|
|
1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (compound 8) is an HIV-1 integrase inhibitor that effectively inhibits both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration reaction. 1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide can be utilized in HIV-1 research .
|
-
- HY-W099790
-
|
1-Butyl-1-methylpiperidinium Bromide
|
Biochemical Assay Reagents
|
Others
|
|
N-butyl-N-methyl-piperidinium bromide is a quaternary ammonium compound belonging to the class of piperidinium salts. N-butyl-N-methyl-piperidinium bromide is commonly used as a phase transfer catalyst in organic synthesis to transfer reactants between immiscible phases. It can also be used as a surfactant, corrosion inhibitor and antibacterial agent. Its unique chemical properties make it an important reagent in many different industries, including pharmaceuticals, agrochemicals, and materials science.
|
-
- HY-W012187R
-
|
|
Drug Metabolite
|
Cancer
|
|
3,5-Di-tert-butyl-4-hydroxybenzaldehyde (Standard) is the analytical standard of 3,5-Di-tert-butyl-4-hydroxybenzaldehyde. This product is intended for research and analytical applications. 3,5-Di-tert-butyl-4-hydroxybenzaldehyde (BHT-CHO) is a metabolite of Butylated hydroxytoluene (HY-Y0172) .
|
-
- HY-W460274
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Aminobutyl-DOTA-tris(t-butyl ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. 4-Aminobutyl-DOTA-tris(t-butyl ester) can be used for conjugation of peptides and radionuclides.
|
-
- HY-131699
-
|
|
Biochemical Assay Reagents
|
Others
|
|
t-Butyl ester-PEG4-CH2COOH is a PEG linker containing a t-butyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl group can be deprotected under acidic conditions.
|
-
- HY-W087240S
-
-
- HY-154995
-
|
|
Glycosidase
|
Infection
|
|
N-4′-(p-Trifluoromethylphenyl)butyl-DAB (compound 5g) is an agonit of lysosomal acid α-glucosidase (GAA). N-4′-(p-Trifluoromethylphenyl)butyl-DAB increases intracellular GAA activities dose-dependently, in Pompe patient's fibroblasts with the M519V mutation .
|
-
- HY-143835
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG9-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-143837
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG12-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132117
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG12-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132067
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132022
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-143836
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG10-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132066
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132109
-
|
|
PROTAC Linkers
|
Cancer
|
|
MS-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132056
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG14-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096076
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG6-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132118
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG10-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132057
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG10-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132034
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG6-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132081
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG10-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132044
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG8-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132071
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methylamino-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132073
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG14-t-butyl-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W190816
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-143838
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG14-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132100
-
|
|
PROTAC Linkers
|
Cancer
|
|
Thiol-PEG2-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140386
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ms-PEG10-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132054
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG17-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140384
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ms-PEG5-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132079
-
|
|
PROTAC Linkers
|
Cancer
|
|
FmocNH-PEG4-t-butyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132080
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG8-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132084
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-PEG8-t-butyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132064
-
|
|
PROTAC Linkers
|
Cancer
|
|
FmocNH-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132101
-
|
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132025
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W325356
-
|
|
Fluorescent Dye
|
Cancer
|
|
Tert-butyl 3,5-dinitrobenzoate is an intermediate or reactant in organic synthesis and can also play a role in drug synthesis, dye preparation and other chemical fields.The nitro functional group of Tert-butyl 3,5-dinitrobenzoate has certain reactivity in organic chemistry and can participate in various reactions, such as electrophilic substitution, aromatic amine reaction, etc .
|
-
- HY-W024365
-
|
|
PROTAC Linkers
|
Cancer
|
|
3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .
|
-
- HY-W003696
-
|
Tert-Butyl 5-bromo-1,3-dihydro-2H-isoindole-2- carboxylate
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl 5-bromoisoindoline-2-carboxylate is a PROTAC Linker. tert-Butyl 5-bromoisoindoline-2-carboxylate can be used in synthesis PTOTAC HSD17B13 degrader 1 (HY-159651) .
|
-
- HY-W017145S
-
-
- HY-W016730S
-
-
- HY-W755252
-
|
BBN
|
DNA Alkylator/Crosslinker
|
Cancer
|
|
N-Butyl-N-(4-hydroxybutyl)nitrosamine is a potent mutagen that can cause high-level of mutagenesis specifically in the epithelial cells (urothelial) of the urinary bladder. N-Butyl-N-(4-hydroxybutyl)nitrosamine is used to induce bladder cancer in rodents .
|
-
- HY-W054292
-
|
(OtBu)KuE(OtBu)2
|
PSMA
|
Cancer
|
|
tert-Butyl-DCL is a small molecule PSMAM inhibitor with anticancer activity that targets prostate-specific membrane antigen (PSMA). tert-Butyl-DCL is also an effective bioimaging agent that has high selectivity and affinity, allowing it to target and highlight specific receptors on the surface of tumor cells .
|
-
- HY-W000830
-
-
- HY-W457953
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl N-(4-azidobutyl)carbamate is N-Boc protected crosslinker. tert-Butyl N-(4-azidobutyl)carbamate can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-W010216S
-
-
- HY-40172
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl (3-aminopropyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W025811
-
-
- HY-79404A
-
|
|
Amino Acid Derivatives
|
Others
|
|
Boc-beta-t-butyl-d-alanine is an intermediate, can be used in the synthesis of peptides and other amino acids .
|
-
- HY-W017140
-
|
SBMP
|
Endogenous Metabolite
|
Others
|
|
2-Sec-butyl-3-methoxypyrazine (SBMP) is a methoxypyrazine and can be identified in the ladybug species .
|
-
- HY-23185
-
-
- HY-W011354
-
-
- HY-135380
-
|
|
Drug Intermediate
|
Cardiovascular Disease
|
|
Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .
|
-
- HY-W749614
-
-
- HY-W011565S1
-
-
- HY-W011565S
-
-
- HY-151772
-
|
|
ADC Linker
|
Others
|
|
Methyltetrazine-PEG12-t-butyl ester is a monodisperse PEG compound. Methyltetrazine-PEG12-t-butyl ester is a click chemistry reagent containing a tetrazine group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
|
-
- HY-132089
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W411604
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl hex-5-ynoate is the linker that can be used for PROTAC synthesis of PROTAC cGAS degrader-1 (HY-172208) .
|
-
- HY-132062
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG11-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG11-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140783
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG15-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG15-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-132061
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG14-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG14-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-132060
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG7-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W129533
-
|
|
Drug Intermediate
|
Others
|
|
tert-Butyl 1H-indol-4-ylcarbamate is a synthetic intermediate useful for pharmaceutical synthesis.
|
-
- HY-172294
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mes-PEG2-CH2-t-butyl ester is a PEG linker consisting of a PEG2 linker for improved water-solubility of the compound and a t-butyl ester group which can be deprotected under acidic conditions. The mesylate serves as an excellent leaving group, offering all the advantages without the limitation of having an acidic proton that could react with nucleophiles.
|
-
- HY-Y1166
-
-
- HY-W578278
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl (2-(pyridin-2-yldisulfanyl)ethyl)carbamate consists of a tert-butyl group, where the protected amine can be deprotected under mild acidic conditions, and the other part of the molecule may act as a thiol-specific labeling reagent, commonly used in reversibly binding cysteine residues on proteins.
|
-
- HY-W017187
-
|
|
Apoptosis
|
Cancer
|
|
2-tert-Butyl-1,4-benzoquinone is an electrophilic metabolite of butylated hydroxyanisole and an oxidation product of 2-tert-butylhydroquinone .
|
-
- HY-W190966
-
|
|
PROTAC Linkers
|
Others
|
|
t-Boc-Aminooxy-PEG4-t-butyl ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-W050151
-
|
|
Bacterial
DNA/RNA Synthesis
|
Infection
|
|
2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent that defends the emerging antibacterial resistance, which is found in marine Streptomyces sp. VITVSK1. 2,5-Di-tert-butyl-1,4-benzoquinone is also a potent inhibitor of RNA polymerase .
|
-
- HY-W283336S
-
-
- HY-W077436S
-
-
- HY-W008201
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl 3-formylpyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W003177
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl 4-iodopiperidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W003140
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W006185
-
-
- HY-W101713
-
-
- HY-44070
-
-
- HY-69260
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl 4-formylpiperidine-1-carboxylate is the linker of PROTAC BRM/BRG1 degrader-3 (HY-168251) .
|
-
- HY-W250574
-
-
- HY-144079
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-C4-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W582827
-
|
|
Biochemical Assay Reagents
Endogenous Metabolite
|
|
|
RuPhos Pd G1 methyl t-butyl ether adduct (MTBE) is a highly efficient catalyst with excellent cross-coupling activity. RuPhos Pd G1 methyl t-butyl ether adduct (MTBE) is widely used in organic synthesis and can be used to promote various reactions to build complex molecular structures. RuPhos Pd G1 methyl t-butyl ether adduct (MTBE) has good adaptability to temperature and reaction conditions, which enables it to exhibit excellent catalytic performance in different reaction systems.
|
-
- HY-133887
-
|
|
Antifolate
DNA/RNA Synthesis
|
Cancer
|
|
Methotrexate α-tert-butyl ester, capped by OtBu, significantly reduces tumor growth in HT1080 tumor bearing mice. Methotrexate is an antimetabolite and antifolate agent and is also an immunosuppressant and antineoplastic agent .
|
-
- HY-W800719
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-N'-(PEG1-t-butyl ester)-L-Lysine-amido-Mal is the amino acid, lysine, with a maleimide at its C-terminus, a Boc-protecting group on its α-amine, and an amido-PEG1-t-butyl ester on its ε-amine. Maleimide is a thiol-reactive covalent group used to conjugate cysteine residues, while the Boc and the t-butyl ester can be later deprotected to perform further reactions.
|
-
- HY-W241345
-
|
|
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
DOTA-bis(tert-butyl)ester is a DOTA-based metal chelator that can bind to radionuclides and is used to prepare radionuclide conjugates (RDCs). DOTA-bis(tert-butyl)ester can be conjugated with different salts to form different metal chelators, such as (HY-B1244) hydrochloride to obtain DOTA-MN2. DOTA-MN2 can be reacted with [67]Ga-citrate to obtain radiolabeling. When (67)Ga-DOTA-MN2 is incubated in phosphate buffer solution or mouse plasma for 24 hours, it does not undergo significant decomposition. In the biodistribution experiment of NFSa tumor mice, it has high tumor uptake and rapid plasma clearance, and is a good material for SPECT and PET studies.
|
-
- HY-W007500
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2,6-Di-Tert-butyl-4-methylpyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W003321
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(S)-tert-Butyl 5-oxopyrrolidine-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-N12344
-
|
|
JNK
|
Inflammation/Immunology
|
|
n-Butyl α-D-fructofuranoside, isolated from the root barks of Ulmus davidiana var. japonica, enhances Nrf2 activity through activation of JNK and has antiinflammation activity .
|
-
- HY-75947
-
-
- HY-W348170
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl((5-iodopentyl)oxy)dimethylsilane is a silane compound with a terminal iodine group. The trimethylsilane is commonly used for surface modifications. The iodine (I) is a very good leaving group for nucleophilic substitution reactions.
|
-
- HY-W598191
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl (3-azidopropyl)carbamate is a reagent containing an azide group and Boc-protected amino group. It is reactive with alkyne, BCN, DBCO via Click Chemistry. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-42994
-
-
- HY-W096080
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Butyl acetate-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096082
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Butyl acetate-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-32208S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate-d4 is the deuterium labeled tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate[1].
|
-
- HY-140584
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Desthiobiotin-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140753
-
|
|
PROTAC Linkers
|
Cancer
|
|
DOTA-(t-butyl)3-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DOTA-(t-butyl)3-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W012187
-
|
BHT-CHO
|
Drug Metabolite
|
Cancer
|
|
3,5-Di-tert-butyl-4-hydroxybenzaldehyde (BHT-CHO) is a metabolite of Butylated hydroxytoluene (HY-Y0172) .
|
-
- HY-W190955
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-(t-butyl ester-PEG3)-N-bis(PEG3-amine) is a PEG reagent that can easily react with activated NHS esters or carboxylic acid in the presence of EDC or HATU. The t-butyl group can be deprotected under acidic conditions. The hydrophilic PEG spacers increase the compounds water solubility in aqueous media.
|
-
- HY-151792
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Pomalidomid-C6-PEG3-butyl-N3 is a click chemistry reagent containing an azide group. Pomalidomid-C6-PEG3-butyl-N3 also is a crosslinker-E3 ligase ligand conjugate, which be used in click reactive protein degrader building block for PROTAC research.
Pomalidomid-C6-PEG3-butyl-N3 also can be used in the template for synthesis of targeted protein degrader . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-W092078
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl (4-iodobutyl)carbamate is a four carbon linker containing a Boc-protected amino group and an iodine group. The Boc group can be deprotected under mild acidic conditions to form the free amine. Iodine (I) is a very good leaving group for nucleophilic substitution reactions.
|
-
- HY-30756
-
|
|
PROTAC Linkers
|
Others
|
|
tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate is a PROTAC linker. tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate is the linker of PROTAC ER Degrader-12 (HY-160264) and PROTAC AR Degrader-9 (HY-170332) .
|
-
![tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate](//file.medchemexpress.eu/product_pic/hy-30756.gif)
- HY-169975
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl 4-(4-(piperazin-1-ylmethyl)piperidin-1-yl)benzoate is a PROTAC linker. tert-Butyl 4-(4-(piperazin-1-ylmethyl)piperidin-1-yl)benzoate can be used to synthesize PROTAC AR Degrader-6 (HY-156751) .
|
-
- HY-140592
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG3-S-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-S-PEG4-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140094
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-40146
-
|
N-Boc-3-azetidinone
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl 3-oxoazetidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W890392
-
|
|
PROTAC Linkers
|
Cancer
|
|
(1r,4r)-tert-Butyl 4-(bromomethyl)cyclohexanecarboxylate is a PROTAC linker used in the synthesis of SMD-1087 (HY-170828) .
|
-
- HY-42773
-
|
1-Boc-1,8-diaminooctane
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl (8-aminooctyl)carbamate (1-Boc-1,8-diaminooctane) can be used as a PROTAC linker in the synthesis of PROTACs. tert-butyl (8-aminooctyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-W088456
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl N-[3-(piperazin-1-yl)propyl]carbamate is a linker that can be used for synthesis of PROTAC degrader TrimTAC1 (HY-169355) .
|
-
![tert-Butyl N-[3-(piperazin-1-yl)propyl]carbamate](//file.medchemexpress.eu/product_pic/hy-w088456.gif)
- HY-W047688
-
|
1-Boc-1,10-diaminodecane
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl (10-aminodecyl)carbamate (1-Boc-1,10-diaminodecane) can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. tert-Butyl (10-aminodecyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-120021
-
|
|
Drug Intermediate
|
Others
|
|
tert-Butyl 4-(1H-indol-4-yl)piperazine-1-carboxylate is a synthetic intermediate useful for pharmaceutical synthesis..
|
-
- HY-W101722
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl (9-aminononyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-W549538
-
|
|
Biochemical Assay Reagents
|
|
|
tert-Butyl β-D-glucopyranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .
|
-
- HY-130422
-
|
Tos-PEG4-Boc
|
PROTAC Linkers
|
Cancer
|
|
Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker, which refers to the PEG composition. Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) can be used in the synthesis of a series of PROTACs, such as BI-3663 (HY-111546). BI-3663 is a highly selective PTK2/FAK PROTAC, with cereblon ligands to hijack E3 ligases for PTK2 degradation, and inhibits PTK2 with an IC50 of 18 nM .
|
-
- HY-W190930
-
|
|
Biochemical Assay Reagents
|
Others
|
|
t-Butyl 1,5-di(ethoxycarbonyl)pentan-3-ylcarbamate is a branched molecule with an n-Boc group and two ethyl ester moieties. The Boc-protected amine can be deprotected under acidic conditions.
|
-
- HY-173163
-
|
|
Bacterial
|
Infection
|
|
(E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) (Compound 4a) is a Gram-negative outer membrane permeabilizer with synergistic antibacterial activity through the blockage on LptA/LptC interaction via targeting Met47 in LptA. (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) potentiates pol B against both wild-typed and MDR A. baumannii and E. coli strains. (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) can be used as antibiotic adjuvants against MDR Gram-negative bacteria .
|
-
- HY-W006205
-
-
- HY-W643129
-
|
|
Drug Derivative
|
Others
|
|
1-(3,5-Di-tert-butyl-4-hydroxyphenyl)ethane-1,2-diol is a sterically hindered para-alkylphenol.
|
-
- HY-W009008
-
-
- HY-W800843
-
|
|
Liposome
|
Cancer
|
|
tert-Butyl 3-(7-((undecan-3-yloxy)carbonyl)heptylamino)propylcarbamate is an aminolipid featuring a Boc-protected primary amine, a propylamine spacer attached to an octanoate chain and a C11 chain.
|
-
- HY-140564
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W454945S
-
|
N-Boc-piperazine-d8
|
Isotope-Labeled Compounds
|
Others
|
|
tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8 is the deuterium labeled tert-Butyl piperazine-1-carboxylate .
|
-
- HY-30120
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl N-[(1S,2S)-2-aminocyclohexyl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
![tert-Butyl N-[(1S,2S)-2-aminocyclohexyl]carbamate](//file.medchemexpress.eu/product_pic/hy-30120.gif)
- HY-20240
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl (6-aminospiro[3.3]heptan-2-yl)carbamate is a linker that can be used for synthesis of PROTAC degrader CPD-39 (HY-168664) .
|
-
![tert-Butyl (6-aminospiro[3.3]heptan-2-yl)carbamate](//file.medchemexpress.eu/product_pic/hy-20240.gif)
- HY-42448
-
-
- HY-140873
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140870
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-N12299
-
|
Quercetin 3-O-β-D-glucuronide Butyl ester
|
Others
|
Cancer
|
|
Parthenosin (Quercetin 3-O-β-D-glucuronide butyl ester) is a flavonoid, that can be isolated from the aerial parts of Calligoum polygonoides. Parthenosin shows cytotoxic activity against HepG2 and MCF-7 cell lines with IC50 values of 60.46 and 61.4 μg/mL, respectively .
|
-
- HY-151791
-
|
|
ADC Linker
|
Others
|
|
(S,R,S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent containing an azide group. (S,R,S)-AHPC-C6-PEG3-butyl-N3 serves as crosslinker-E3 ligase ligand conjugate, Click reactive protein degrader building block for PROTAC research, Template for synthesis of targeted protein degrader, VH032 conjugate . (S,R,S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W089233
-
|
N-Boc-D-glutaMic acid 1-tert-Butyl ester
|
Amino Acid Derivatives
|
Others
|
|
Boc-D-Glu-OtBu (N-Boc-D-glutaMic acid 1-tert-butyl ester) is an amino acid derivative with a Boc protecting group, which can be used to synthesize Adamant-1-yl tripeptide with immunostimulatory activity .
|
-
- HY-W440436S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(tert-butyl)phenol-d4 is deuterium labeled 2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(tert-butyl)phenol .
|
-
![2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(tert-butyl)phenol-d4](//file.medchemexpress.eu/product_pic/hy-w440436s.gif)
- HY-W454729S
-
|
4-Hydroxypiperidine-3,3,4,5,5-d5-N-t-BOC
|
Isotope-Labeled Compounds
|
Others
|
|
tert-Butyl 4-hydroxypiperidine-1-carboxylate-3,3,4,5,5-d5 is the deuterium labeled tert-Butyl 4-hydroxypiperidine-1-carboxylate .
|
-
- HY-W460133
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl (2-(2-(2-iodoethoxy)ethoxy)ethyl)carbamate is a PEG linker containing a Boc protected amine and an iodine group. The protected amine can be deprotected under mild acidic conditions. Iodine (I) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
|
-
- HY-W011886S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
N2-(tert-Butyl)-N4-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine-d9 is the deuterium labeled N2-(tert-Butyl)-N4-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine .
|
-
- HY-W800653
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-(Azido-PEG3)-NH-PEG3-t-butyl ester is a click chemistry reagent with a terminal azide group and secondary amine NH group. NH group is reactive with NHS ester, The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The azide group can participate in Click Chemistry.
|
-
- HY-135208
-
|
|
Drug Intermediate
|
Neurological Disease
|
|
tert-Butyl 2-(5-chloro-2,2'-dioxospiro[indole-3,3'-pyrrolidine]-1-yl)acetate is an intermediate used in the synthesis of potent DP2 receptor antagonists based on a novel spiro-indolinone compound .
|
-
![tert-Butyl 2-(5-chloro-2,2'-dioxospiro[indole-3,3'-pyrrolidine]-1-yl)acetate](//file.medchemexpress.eu/product_pic/hy-135208.gif)
- HY-Y1169
-
|
4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate; Fmoc-L-Asp(OtBu)-OH
|
Amino Acid Derivatives
|
Others
|
|
Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is an aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
|
-
- HY-152333
-
|
|
Nucleoside Antimetabolite/Analog
|
Cancer
|
|
7-n-Butyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
-
- HY-Y1169S2
-
|
4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d3; Fmoc-L-Asp(OtBu)-OH-d3
|
Isotope-Labeled Compounds
Amino Acid Derivatives
|
Others
|
|
Fmoc-Asp(OtBu)-OH-d3 (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d3) is deuterium labeled Fmoc-Asp(OtBu)-OH. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
|
-
- HY-W017140S
-
|
SBMP-d3
|
Isotope-Labeled Compounds
|
Others
|
|
2-Sec-butyl-3-methoxypyrazine-d3 is deuterated labeled cis-?Jasmone (HY-N7058). Cis-Jasmone is a plant-derived natural product. Cis-Jasmone is constitutively released by many flowers and sometimes by leaves as an attractant for pollinators or as a chemical cue for host location by insect flower herbivores. Cis-Jasmone treatment of crop plants not only induces direct defense against herbivores, but also induces indirect defense by releasing VOCs that attract natural enemies .
|
-
- HY-W575291
-
|
N-Boc-oct-7-yn-1-amine
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl oct-7-yn-1-ylcarbamate (N-Boc-oct-7-yn-1-amine) is crosslinker consisting of a propargyl group and a t-Boc protected amine group. The propargyl group reacts with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry reactions. The t-Boc protected amine can be deprotected under mild acidic conditions.
|
-
- HY-W102278S
-
|
2,4-Di-tert-Butyl-6-(5-chloro-2H-benzotriazol-2-yl)phenol-d3(UV-327-d3)
|
Isotope-Labeled Compounds
|
Others
|
|
Tinuvin-327-d3 (2,4-Di-tert-Butyl-6-(5-chloro-2H-benzotriazol-2-yl)phenol-d3 (UV-327-d3)) is deuterium labeled 2,4-Di-tert-butyl-6-(5-chloro-2H-benzo[d][1,2,3]triazol-2-yl)phenol .
|
-
- HY-401269
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl (2-(4-(2-(5-(3,5-dimethylisoxazol-4-yl)-1-(2-morpholinoethyl)-1H-benzo[d]imidazol-2-yl)ethyl)phenoxy)ethyl)carbamate is a biological molecule.
|
-
![tert-Butyl (2-(4-(2-(5-(3,5-dimethylisoxazol-4-yl)-1-(2-morpholinoethyl)-1H-benzo[d]imidazol-2-yl)ethyl)phenoxy)ethyl)carbamate](//file.medchemexpress.eu/product_pic/hy-401269.gif)
- HY-400345
-
|
|
Biochemical Assay Reagents
|
Others
|
|
t-butyl-C18-D-Glu-OtBu is comprised of an octadecanedioic acid with a terminal t-butyl ester and a glutamic acid, which is also protected by a terminal t-butyl ester. The t-butyl groups can be deprotected under acidic conditions. Glutamic acid is an α-amino acid that is used in the biosynthesis of proteins.
|
-
- HY-22055B
-
|
(2S,4S)-1-tert-Butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate
|
Drug Intermediate
|
Infection
|
|
AN-12-H5 intermediate-1 ((2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate) is an intermediate of the viral inhibitor AN-12-H5 (HY-120900) and can be used to synthesize Antibody-Drug Conjugates (ADCs).
|
-
- HY-133813AR
-
|
|
Drug Metabolite
|
Neurological Disease
|
|
2,4-D Butyl ester (Standard) is the analytical standard of 2,4-D Butyl ester. This product is intended for research and analytical applications. 2,4-D Butyl ester is an organic phenoxy herbicide and used to control woody broad-leaf weeds. 2,4-D butyl ester produces its herbicidal effect by mimicking natural plant growth hormones causing plants to grow too rapidly to survive .
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-
- HY-141902S
-
-
- HY-W010549R
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
3-tert-Butyl-4-methoxyphenol (Standard) is the analytical standard of 3-tert-Butyl-4-methoxyphenol. This product is intended for research and analytical applications. 3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .
|
-
- HY-100651R
-
|
|
Reference Standards
Drug Metabolite
|
Neurological Disease
|
|
3,5-Di-tert-butyl-4-hydroxybenzaldehyde (Standard) is the analytical standard of 3,5-Di-tert-butyl-4-hydroxybenzaldehyde. This product is intended for research and analytical applications. 3,5-Di-tert-butyl-4-hydroxybenzaldehyde (BHT-CHO) is a metabolite of Butylated hydroxytoluene (HY-Y0172) .
|
-
- HY-17528
-
|
Cyhalofop acid
|
Drug Metabolite
|
Others
|
|
Cyhalofop (Cyhalofop acid), the primary metabolite of Cyhalofop-butyl (HY-B0861) in susceptible grasses, is the herbicidally active metabolite. Cyhalofop-butyl is an aryloxyphenoxypropionate post-emergence herbicide widely used around the world in agriculture .
|
-
- HY-134106
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-erythro-sphingosine is composed of t-butyl ester protected N-acetylsphingosine with a fatty acid tail. The hydroxy group enables further derivatization or replacement with other reactive functional groups. The t-butyl group can be deprotected under mild acidic conditions.
|
-
- HY-152040S
-
|
3-(Acetyl-13C2)-5-((S)-sec-Butyl)-4-hydroxy-1,5-dihydro-2H-pyrrol-2-one
|
Isotope-Labeled Compounds
|
Others
|
|
Tenuazonic acid-(acetyl- 13C2) (mixture of diastereomers) in methanol (3-(Acetyl- 13C2)-5-((S)-sec-butyl)-4-hydroxy-1,5-dihydro-2H-pyrrol-2-one) is 13C labeled Tenuazonic acid-(acetyl) (mixture of diastereomers) in methanol .
|
-
- HY-W039458
-
|
|
Biochemical Assay Reagents
|
Others
|
|
10-(tert-Butoxy)-10-oxodecanoic acid is a short linker featuring a carboxylic acid and a tert-butyl ester. Carboxylic acids can be linked with alcohols or amines, while the tert-butyl ester can be selectively deprotected to allow for reactivity as a carboxylic acid to form esters or amides.
|
-
- HY-141398
-
|
Methyl-PEG9-t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
m-PEG9-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141397
-
|
Methyl-peg8-t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
m-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-A0052S
-
|
Telaprevir, (R)-d4
|
Isotope-Labeled Compounds
|
Others
|
|
(1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide-d4 is deuterated labeled (1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide.
|
-
![(1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide-d4](//file.medchemexpress.eu/product_pic/hy-a0052s.gif)
- HY-17528R
-
|
|
Drug Metabolite
|
Others
|
|
Cyhalofop (Standard) is the analytical standard of Cyhalofop. This product is intended for research and analytical applications. Cyhalofop (Cyhalofop acid), the primary metabolite of Cyhalofop-butyl (HY-B0861) in susceptible grasses, is the herbicidally active metabolite. Cyhalofop-butyl is an aryloxyphenoxypropionate post-emergence herbicide widely used around the world in agriculture .
|
-
- HY-15876R
-
|
|
Drug Metabolite
P2Y Receptor
|
Cardiovascular Disease
|
|
Cyhalofop (Standard) is the analytical standard of Cyhalofop. This product is intended for research and analytical applications. Cyhalofop (Cyhalofop acid), the primary metabolite of Cyhalofop-butyl (HY-B0861) in susceptible grasses, is the herbicidally active metabolite. Cyhalofop-butyl is an aryloxyphenoxypropionate post-emergence herbicide widely used around the world in agriculture .
|
-
- HY-W014394R
-
|
|
TRP Channel
|
Cardiovascular Disease
|
|
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
|
-
- HY-W190948
-
|
|
Biochemical Assay Reagents
|
Others
|
|
10-(tert-Butoxy)-10-oxodecanoic NHS ester has a t-butyl ester group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond.
|
-
- HY-W190906
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-(tert-Butoxy)-6-oxohexanoic NHS ester has a t-butyl ester group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond.
|
-
- HY-W777679
-
-
- HY-W349628
-
|
|
Drug Metabolite
|
Others
|
|
Dibutyl 3-hydroxybutyl phosphate is a predominant metabolite of tris( n-butyl) phosphate (TNBP). TNBP is a commonly used alkyl organophosphate ester .
|
-
- HY-N8445
-
|
|
Aryl Hydrocarbon Receptor
|
Others
|
|
Glucoerucin potassium is an aryl hydrocarbon receptor antagonist and is the 4-methylthio-butyl glucosinolate found in the seeds of Eruca sativa Mill .
|
-
- HY-N9924
-
-
- HY-131266R
-
|
|
Drug Metabolite
|
Others
|
|
Menadione bisulfite (sodium) (Standard) is the analytical standard of Menadione bisulfite (sodium). This product is intended for research and analytical applications. Menadione bisulfite (sodium) is used as an agent to induce acute oxidative stress, and to function as a plant-defense activator against several pathogens.
|
-
- HY-141399
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG10-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-40174A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-Butyl (2-aminoethyl)(methyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W131541
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl (11-aminoundecyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. tert-Butyl (11-aminoundecyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-W017140R
-
|
|
Endogenous Metabolite
|
Others
|
|
Ricinine (Standard) is the analytical standard of Ricinine. This product is intended for research and analytical applications. Ricinine exhibits hepatoprotection in CCl4 -induced liver damage .
|
-
- HY-76366
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W190972
-
|
|
Drug Derivative
|
Others
|
|
3-(3-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole is a PEG derivative containing a tert-butyl ester and an azide group .
|
-
- HY-163012
-
-
- HY-106392
-
|
NB-DGJ; N-(n-Butyl)deoxygalactonojirimycin
|
Glucosylceramide Synthase (GCS)
|
Metabolic Disease
|
|
Lucerastat, the galactose form of Miglustat, is an orally-available inhibitor of glucosylceramide synthase (GCS). Lucerastat has the potential for Fabry disease study .
|
-
- HY-23020
-
|
|
Proteasome
|
Cancer
|
|
Boc3Arg is the tert-butyl carbamate-protected arginine. Boc3Arg is an efficient tag to induce degradation through directly localizing the protein to the 20S proteasome .
|
-
- HY-W002421
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-butyl N-[(3R)-pyrrolidin-3-yl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W739814
-
-
- HY-W714205S
-
-
- HY-N1506
-
|
|
Epigenetic Reader Domain
p38 MAPK
|
Cancer
|
|
Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity .
|
-
- HY-B1430R
-
|
|
Calcium Channel
Sodium Channel
Potassium Channel
|
Neurological Disease
|
|
Butamben (Standard) is the analytical standard of Butamben. This product is intended for research and analytical applications. Butamben (Butyl 4-aminobenzoate) results in long-lasting relief from pain, without impairing motor function or other sensory functions .
|
-
- HY-W598193
-
|
|
Biochemical Assay Reagents
|
Others
|
|
[(5-Azidopentyl)oxy](tert-butyl)dimethylsilane is a silane compound with a terminal azide group. The trimethylsilane is commonly used for surface modifications. The terminal azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry.
|
-
dimethylsilane](//file.medchemexpress.eu/product_pic/hy-w598193.gif)
- HY-140156
-
|
Methylamino-PEG4-t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Methylamino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140616
-
|
DNP-PEG6-t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
DNP-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141328
-
|
Thiol-PEG4-t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Thiol-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140154
-
|
Methylamino-PEG1-t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Methylamino-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141327
-
|
Thiol-PEG3-t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Thiol-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140155
-
|
Methylamino-PEG2-t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Methylamino-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-106392R
-
|
NB-DGJ (Standard); N-(n-Butyl)deoxygalactonojirimycin (Standard)
|
Glucosylceramide Synthase (GCS)
|
Metabolic Disease
|
|
Lucerastat (Standard) is the analytical standard of Lucerastat. This product is intended for research and analytical applications. Lucerastat, the galactose form of Miglustat, is an orally-available inhibitor of glucosylceramide synthase (GCS). Lucerastat has the potential for Fabry disease study .
|
-
- HY-W598194
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-((4-Azidobutoxy)methyl)-4-methoxybenzene is a compound with a methyl phenol group and a butyl tail ending in a terminal azide. The azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
|
-
- HY-141210
-
|
Hydroxy-PEG5-t-Butyl acetate
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG5-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W127622
-
|
3-(4-(tert-Butyl)pyridinio)-1-propanesulfonate
|
Biochemical Assay Reagents
|
Others
|
|
NDSB 256-4T is a non-washing sulfabetaine compound. NDSB-256-4T prevents protein aggregation and promotes protein folding by interacting with early folding intermediates .
|
-
- HY-140032
-
|
Alkyne-ethyl-PEG1-t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Alkyne-ethyl-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Alkyne-ethyl-PEG1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-103502
-
CGP7930
1 Publications Verification
|
GABA Receptor
|
Neurological Disease
|
|
CGP7930 (3-(3’,5’-Di-tert-butyl-4’-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. CGP7930 enhances the inhibitory effect of l-baclofen on the oscillatory activity of cultured cortical neurons .
|
-
- HY-W909314
-
|
|
Biochemical Assay Reagents
|
Others
|
|
t-Butyoxycarboxy-PEG4-para-nitrophenyl carbonate is a PEG linker with a nitrophenyl group linked to a carbonate, four PEG units, and a t-butyl group that can be deprotected under acidic conditions. The PEG units enhance the solubility of the molecule in aqueous media. Nitrophenyl group is reactive towards the amino-bearing molecules.
|
-
- HY-W017330
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Methacrylic anhydride is a typical polymerizable 1,6-diolefin. Methacrylic anhydride can form a soluble csyclopolymer by free-radical initiation. Methacrylic anhydride can spontaneously polymerize through the vinyl group and justifies the use of 2-6-di-tert-butyl4-methylphenol as an inhibitor .
|
-
- HY-N1791
-
|
|
Others
|
Infection
|
|
3, 5-diprenyl-4-hydroxybenzaldehyde is an isoprene phenyl butyl aldehyde. 3, 5-diprenyl-4-hydroxybenzaldehyde had the ability to inhibit biofilm formation in strains. 3, 5-diprenyl-4-hydroxybenzaldehyde can be used to study the potential synergistic effect of clinically relevant antibiotics .
|
-
- HY-W343292S1
-
-
- HY-140347
-
|
tert-Butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate
|
PROTAC Linkers
|
Cancer
|
|
APN-C3-NH-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . APN-C3-NH-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W002680
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
N-Boc-cis-4-hydroxy-D-proline methyl ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-D-proline methyl ester is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1
|
-
- HY-W017882
-
|
|
ADC Linker
PROTAC Linkers
|
Cancer
|
|
Boc-trans-D-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-trans-D-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-N2996
-
|
|
HIV Protease
|
Infection
|
|
Ganodermanondiol is a melanogenesis inhibitor isolated from the Ganoderma lucidum .Ganodermanondiol exhibits potent cytoprotective effects on tert-butyl hydroperoxide-induced hepatotoxicity . Ganodermanondiol shows significant anti-HIV-1 protease activity with an IC50 of 90 μM . Ganodermanondiol exhibits a strong anticomplement activity against the classical pathway of the complement system with an IC50 of 41.7μM .
|
-
- HY-Y1169S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Fmoc-Asp(OtBu)-OH- 13C4, 15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH . Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
|
-
- HY-W614269
-
|
|
Radionuclide-Drug Conjugates (RDCs)
|
Others
|
|
DOTA-GA(tBu)4 is a DOTA derivative similar to NOTA-GA. DOTA-GA(tBu)₄ is a tert-butyl-protected chelating agent used for the synthesis of DOTA-GA-TATE conjugates. The structure of DOTA-GA(tBu)4 allows for convenient conjugation to the N-terminus of peptides. DOTA-GA(tBu)4 can be used in research on medical imaging and diagnosis .
|
-
- HY-140791
-
|
17-(Azide-PEG9-ethylcarbamoyl)heptadecanoic t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Azide-PEG9-amido-C16-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C16-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140788
-
|
5-(Azide-PEG9-ethylcarbamoyl)pentanoic t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Azide-PEG9-amido-C4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-79513
-
|
tert-Butyl [(R)-1-(methoxycarbonyl)-2-hydroxyethyl]carbamate
|
Amino Acid Derivatives
|
Others
|
|
(R)-Methyl 2-(tert-butoxycarbonylamino)-3-hydroxypropanoate is a serine derivative .
|
-
- HY-140787
-
|
17-(Azide-PEG6-ethylcarbamoyl)heptadecanoic t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Azide-PEG6-amido-C16-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG6-amido-C16-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140789
-
|
9-(Azide-PEG9-ethylcarbamoyl)nonanoic t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Azide-PEG9-amido-C8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C8-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140588
-
|
N-Benzyl-N-bis(PEG3-t-Butyl ester)
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-N-bis(PEG3-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140201
-
|
17-(Amino-PEG6-ethylcarbamoyl)heptadecanoic t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG6-amido-C16-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140202
-
|
17-(Amino-PEG9-ethylcarbamoyl)heptadecanoic t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Amino-PEG9-amido-C16-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140790
-
|
13-(Azide-PEG9-ethylcarbamoyl)tridecanoic t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
Azide-PEG9-amido-C12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C12-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W190920
-
|
|
Biochemical Assay Reagents
|
Others
|
|
t-Butoxycarbonyl-PEG2-NHS ester has a t-Boc protecting group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
|
-
- HY-132994
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TVD-0003510 is a carboxamide derivative, and involves in synthesis of (2-((6-(2-aminopyrimidine-5-carboxamido)-8-methoxy-3,4-dihydro-2H-pyrimido[1,2-c]quinazolin-9-yl)oxy)ethyl)piperazine-l-carboxylate (C51), as a part of tert-butyl2-(4-hydroxyphenyl)acetate .
|
-
- HY-172625
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
VH 101-amide-piperidine-Pip-alkyne is an E3 Ligase Ligand-Linker Conjugates that can be used to synthesize PROTAC degrader. The linker part of VH 101-amide-piperidine-Pip-alkyne is tert-Butyl 4-ethynyl-[1,4'-bipiperidine]-1'-carboxylate (HY-W442074), and the VHL-type E3 ubiquitinase ligand is VH 101, acid (HY-47070) .
|
-
- HY-W343292S
-
-
- HY-14562
-
|
|
mAChR
Amyloid-β
|
Neurological Disease
Inflammation/Immunology
|
|
TBPB (tert-butyl peroxybenzoate) is a highly selective, blood-brain-permeable M1 mAChR allosteric agonist (EC50=289 nM) with anti-schizophrenia and anti-inflammatory activities. TBPB can enhance the sensitivity of M1 receptors to acetylcholine, activate downstream signaling pathways, and inhibit the release of pro-inflammatory cytokines (TNF-α, IL-6). TBPB can regulate the processing of amyloid and can be used in the study of neurodegenerative diseases (such as Alzheimer's disease) and inflammation-related diseases (such as sepsis) .
|
-
- HY-140568
-
|
N-(Hydroxy-PEG3)-N-Boc-PEG4-t-Butyl ester
|
PROTAC Linkers
|
Cancer
|
|
N-(Hydroxy-PEG3)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-129907
-
|
2-Aminoethyl methylphosphonate
|
GABA Receptor
|
Neurological Disease
|
|
2-AEMP (2-Aminoethyl methylphosphonate) is an anti-GABA(A)-ρ1 receptor compound with antagonist activity. 2-AEMP exhibits competitive inhibition compared to TPMPA with an IC(50) value of 18 μM, compared to 7 μM for TPMPA. The release rate of inhibition at termination of 2-AEMP is significantly higher than that of TPMPA. The preincubation time required for the onset of inhibition of 2-AEMP is much shorter than that of TPMPA. Some analogs of 2-AEMP, especially those with benzyl or n-butyl substituents, show lower potency in terms of biological activity .
|
-
- HY-169355
-
|
|
PROTACs
|
Cancer
|
|
TrimTAC1 is a PROTAC degrader that selectively targets the degradation of the multimeric protein Nucleoporin . TrimTAC1 is composed of PROTAC target protein ligand (red part) (+)-JQ-1 (HY-13030), E3 ligase ligand (blue part) Acepromazine-OTs (HY-169356) and PROTAC linker (black part) tert-Butyl N-[3-(piperazin-1-yl)propyl]carbamate (HY-W088456). Among them, its E3 ligase ligand + linker can form Acepromazine-1-Piperazinepropanamine (HY-169357).
|
-
- HY-133079
-
|
tetra-isopalmitoyl Ascorbic acid; IPAA; Tetrahexyldecyl Ascorbate
|
Prostaglandin Receptor
|
Endocrinology
|
|
Ascorbyl tetra-2-hexyldecanoate (tetra-isopalmitoyl Ascorbic acid; IPAA) is a lipophilic derivative of vitamin C (L-ascorbic acid). Ascorbyl tetra-2-hexyldecanoate (100 μM ) can prevent the decrease in viability of HaCaT keratinocytes induced by UVB, hydrogen peroxide, or tert-butyl hydroperoxide, and reduce the production of IL-1α and prostaglandin E2 (PGE2). Topical application of ascorbyl tetra-2-hexyldecanoate (1%) increases epidermal viability thickness, stratum corneum water content, and skin smoothness, and reduces skin roughness in hairless mice. Ascorbyl tetra-2-hexyldecanoate can be used to develop skin whitening agents in the beauty industry.
|
-
- HY-170828
-
|
|
PROTACs
SWI/SNF Complex
|
Others
|
|
SMD-1087 is a PROTAC that selectively targets SMARCA2 (DC50=8 nM, Dmax=89%) and SMARCA4 with a DC50 of 1 μM. SMD-1087 consists of the E3 ligase ligand (S,R,S)-AHPC-Me (blue part) (HY-112078), the target protein ligand SMI-1074 (red part) (HY-170817), and the PROTAC linker (1r,4r)-tert-Butyl 4-(bromomethyl)cyclohexanecarboxylate (black part) (HY-W890392). Among them, its target protein ligand + Linker part corresponds to SMARCA2 Ligand-Linker Conjugate-1 (HY-170829) .
|
-
- HY-170340
-
|
|
PROTACs
Estrogen Receptor/ERR
|
Cancer
|
|
PROTAC ER Degrader-14 (compound 86) is a PTORAC-type Estrogen Receptor/ERR degrader, which is composed of E3 ubiquitin ligase ligand (blue part) (S)-Deoxy-thalidomide (HY-168055), PROTAC Linker (black part) N-Boc-piperazine (HY-30105) and target protein ligand (red part) ER ligand-6 (HY-170341). Among them, E3 ligase + Linker constitute tert-Butyl (S)-4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperazine-1-carboxylate (HY-W998234) .
|
-
- HY-159651
-
|
|
PROTACs
17β-HSD
|
Cancer
|
|
PTOTAC HSD17B13 degrader 1 (compound 1) is a PROTAC targeting 17β-HSD 13 (HSD17B13). PTOTAC HSD17B13 degrader 1 is composed of PROTAC target protein ligand HSD17B13 degrader 2 (HY-159662) (red part), PROTAC Linker tert-Butyl 5-bromoisoindoline-2-carboxylate (HY-W003696) (black part) and E3 ubiquitin ligase ligand E3 ligase Ligand 31 (HY-159660) (blue part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is E3 Ligase Ligand-linker Conjugate 114 (HY-159661) [1] .
|
-
- HY-100138
-
|
|
Radionuclide-Drug Conjugates (RDCs)
ADC Linker
|
Cancer
|
|
2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) is a metal chelator precursor containing a DOTA macrocyclic structure. DOTA can form highly stable complexes with metal ions (such as 68Ga, 177Lu) through four nitrogen atoms and four carboxylic acid groups to mediate targeted delivery of radionuclides. The tert-butyl ester group (tBu ester) of 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) also protects the carboxylic acid group during synthesis, and forms a free carboxyl group after deprotection reaction for coupling with targeting molecules (such as antibodies, peptides). 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester) may be combined with tumor pre-targeting systems through bioorthogonal reactions (such as reverse electron demand Diels-Alder reaction) to study radioactive imaging or therapy of tumor tissues, and is mainly used in tumor pre-targeting research in the field of nuclear medicine .
|
-
- HY-161958
-
|
|
PROTACs
Histone Acetyltransferase
|
Cancer
|
|
dCE-2 (compound 5) is a PROTAC targeting CREB binding protein (CBP) and E1A-associated protein (EP300), which was developed based on the crystal structure of bromodomain (BRD) inhibitors. dCE-2 is composed of E3 ubiquitin ligase ligand Thalidomide-4-OH (HY-103596) (blue part), PROTAC Linker tert-Butyl 11-aminoundecanoate (HY-130715) (black part) and PROTAC target protein ligand EP300/CBP ligand 2 (HY-161960) (red part), of which the target protein ligand activity control is EP300/CBP ligand 1 (HY-161959), and the conjugate of E3 ubiquitin ligase ligand + Linker is Thalidomide-NH-C10-Boc (HY-161961) [1] .
|
-
- HY-79046
-
|
Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (S)-; Butyric acid, 2-(carboxyamino)-, N-tert-Butyl ester, L- (8CI); (2S)-2-(tert-Butoxycarbonylamino)butanoic acid; (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]butanoic acid
|
Amino Acid Derivatives
|
Others
|
|
Boc-L-2-aminobutanoic acid is an alanine derivative .
|
-
- HY-114402
-
|
|
PROTACs
Androgen Receptor
|
Cancer
|
ARD-69 is a PROTAC degrader based on the E3 ubiquitin ligase VHL and targeting the androgen receptor, which can induce androgen receptor (AR) protein degradation in AR-positive prostate cancer cells. ARD-69 inhibits AR-regulated gene expression, binds to the AR ligand binding domain at one end and binds to VHL at the other end, prompting AR to be recruited to the E3 ubiquitin ligase complex, triggering proteasome degradation, thereby inhibiting AR signaling pathways and downstream gene expression (such as PSA, TMPRSS2). ARD-69 can be used to study the treatment of castration-resistant prostate cancer (mCRPC) .
ARD-69 is composed of a target protein ligand (pink part) AR antagonist 14 (HY-172624), a PROTAC linker (black part) tert-Butyl 4-ethynyl-[1,4'-bipiperidine]-1'-carboxylate (HY-W442074), and a VHL-type E3 ubiquitinase ligand (blue part) VH 101, acid (HY-47070); among them, the VHL ligand and the linker can form a conjugate VH 101-amide-piperidine-Pip-alkyne (HY-172625).
|
-
- HY-162816
-
|
|
PROTACs
MAP4K
|
Cancer
|
|
PROTAC HPK1 Degrader-3 (compound C3) is an orally effective PROTAC targeting HPK1 (DC50=21.26 nM). HPK1 is a negative regulator of T cell receptors, which can lead to T cell dysfunction after abnormal activation. PROTAC HPK1 Degrader-3 can inhibit SLP76 and NF-κB signaling pathways and inhibit MAPK signal transduction, and has anticancer activity and immune activation. PROTAC HPK1 Degrader-3 has a certain oral bioavailability and can be combined with PD-L1 antibody therapy to achieve a tumor growth inhibition rate of 65.58%. PROTAC HPK1 Degrader-3 is composed of E3 ligase ligand Thalidomide (HY-14658; blue part), PROTAC linker tert-Butyl 3-oxoazetidine-1-carboxylate (HY-40146; black part), and target protein ligand HPK1-IN-51 (HY-162842; red part); the activity control of the target protein ligand can be HPK1 ligand 1 (HY-162841) [1] .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-W012482
-
|
|
Dyes
|
|
5-(tert-Butyl)isobenzofuran-1,3-dione is a intermediate and dye. 5-(tert-Butyl)isobenzofuran-1,3-dione has a synonym of 4-tert-Butylphthalic Anhydride .
|
-
- HY-Y1778
-
|
|
Dyes
|
|
N-(Diphenylmethylene)glycine tert-butyl ester is a dye, also as the raw material and intermediate for organic syntheses .
|
-
- HY-172717
-
|
|
Fluorescent Dyes/Probes
|
|
TAMRA-PEG4-t-butyl ester is a TAMRA red-fluorescent dye linker, with excitation/emission maximum 553/575 nm, containing a t-butyl protected carboxyl group which can be deprotected under acidic conditions.
|
| Cat. No. |
Product Name |
Type |
-
- HY-107346
-
|
Butyl cyanoacrylate
|
Thickeners
|
|
Enbucrilate (Butyl cyanoacrylate) is a cyanoacrylate ester that has been used as surgical tissue adhesive.
|
-
- HY-W127330
-
|
|
Biochemical Assay Reagents
|
|
Butyl Laurate is an ester compound with a fruity odor commonly used as a flavoring agent in the food and beverage industry. In addition, it is used as a solvent, plasticizer or lubricant in various industrial applications. Its unique chemical properties make it an important ingredient in a variety of commercial products, including cosmetics, personal care products and cleaners.
|
-
- HY-W127338
-
|
|
Biochemical Assay Reagents
|
|
Butyl Palmitate is an ester compound commonly used as a conditioning, emollient or fragrance in a variety of cosmetic and personal care products. In addition, it can be used as a solvent or lubricant in various industrial applications. Its unique chemical properties make it an important ingredient in a variety of commercial products, including perfumes, lotions and hair care products.
|
-
- HY-W011187
-
-
- HY-W127382
-
|
Ricinolic acid Butyl ester
|
Biochemical Assay Reagents
|
|
Butyl Ricinoleate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W099584
-
|
Myristic scid Butyl ester
|
Biochemical Assay Reagents
|
|
Butyl tetradecanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W030286
-
-
- HY-W127377
-
|
|
Drug Delivery
|
|
Butyl oleateIt is an organic compound belonging to esters. It is formed from the reaction of butanol and oleic acid and has a mild fruity smell. Butyl oleateIt has a variety of applications in the cosmetic and personal care industries, especially as an emollient and conditioning agent in skin and hair care products. Additionally, it is used as a lubricant and solvent in industrial settings.
|
-
- HY-W127520
-
|
|
Biochemical Assay Reagents
|
|
Butyl n-Octanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W154216
-
|
|
Carbohydrates
|
|
Butyl α-D-glucopyranoside can be used in glycobiology research.
|
-
- HY-W014540
-
|
tert-Butyl L-prolinate hydrochloride
|
Cell Assay Reagents
|
|
L-Proline tert-butyl ester hydrochloride (tert-Butyl L-prolinate hydrochloride) is a biologically active compound that has the activity of inhibiting cysteine and cathepsins, and is therefore widely used in the research and development of protease inhibitors. The characteristics of L-Proline tert-butyl ester hydrochloride make it of great significance in the field of biochemistry.
|
-
- HY-W016155R
-
|
|
Biochemical Assay Reagents
|
|
2-Butyl-4-chloro-5-formylimidazole (Standard) is the analytical standard of 2-Butyl-4-chloro-5-formylimidazole. This product is intended for research and analytical applications. 2-Butyl-4-chloro-5-formylimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W016638
-
|
1-Butyl-1-methylpyrrolidin-1-ium chloride
|
Biochemical Assay Reagents
|
|
1-Butyl-1-methylpyrrolidin-1-ium chloride, also known as BMIM chloride, belongs to the class of ionic liquids and consists of a positively charged pyrrolidine cation and a negatively charged chloride anion. This compound is commonly used as a solvent for various chemical reactions, especially those involving organic compounds and metals. Its unique physical and chemical properties, such as low volatility, high thermal stability, and tunable solubility, make it useful in a range of applications in catalysis, electrochemistry, and separation science. Furthermore, 1-butyl-1-methylpyrrolidin-1-ium chloride may have potential applications as a green solvent in energy storage devices and various industrial processes.
|
-
- HY-W283556
-
|
|
Chelators
|
|
DO2A-tert-butyl ester is a bifunctional chelator (BFC) that can be used for the coupling of peptides and radionuclides. DO2A-tert-butyl ester can be used in the development of radionuclide imaging tracers .
|
-
- HY-W016155
-
|
|
Biochemical Assay Reagents
|
|
2-Butyl-4-chloro-5-formylimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-126070
-
|
|
Microbial Culture
|
|
N-Butyl cinnamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-W002322
-
|
|
Biochemical Assay Reagents
|
|
tert-Butyl 2-(diethoxyphosphoryl)acetate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W451440
-
|
|
Chelators
|
|
Butyne-DOTA-tris(t-butyl ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. Butyne-DOTA-tris(t-butyl ester) can be used for conjugation of peptides and radionuclides.
|
-
- HY-60280
-
|
|
Biochemical Assay Reagents
|
|
Di-tert-butyl iminodicarboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W127701
-
|
1-Butyl-1-methylpiperidinium bis(trifluoromethylsulfonyl)imide
|
Biochemical Assay Reagents
|
|
[Bmpip][NTf2] is composed of 1-butyl-1-methylimidazolium cation and bis(trifluoromethylsulfonyl)imide anion.
|
-
- HY-W099790
-
|
1-Butyl-1-methylpiperidinium Bromide
|
Biochemical Assay Reagents
|
|
N-butyl-N-methyl-piperidinium bromide is a quaternary ammonium compound belonging to the class of piperidinium salts. N-butyl-N-methyl-piperidinium bromide is commonly used as a phase transfer catalyst in organic synthesis to transfer reactants between immiscible phases. It can also be used as a surfactant, corrosion inhibitor and antibacterial agent. Its unique chemical properties make it an important reagent in many different industries, including pharmaceuticals, agrochemicals, and materials science.
|
-
- HY-W460274
-
|
|
Chelators
|
|
4-Aminobutyl-DOTA-tris(t-butyl ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. 4-Aminobutyl-DOTA-tris(t-butyl ester) can be used for conjugation of peptides and radionuclides.
|
-
- HY-W054292
-
|
(OtBu)KuE(OtBu)2
|
Biochemical Assay Reagents
|
|
tert-Butyl-DCL is a small molecule PSMAM inhibitor with anticancer activity that targets prostate-specific membrane antigen (PSMA). tert-Butyl-DCL is also an effective bioimaging agent that has high selectivity and affinity, allowing it to target and highlight specific receptors on the surface of tumor cells .
|
-
- HY-40172
-
|
|
Biochemical Assay Reagents
|
|
tert-Butyl (3-aminopropyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W749614
-
|
|
Chelators
|
|
NO2A-Butyne-bis(t-Butyl ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Butyne-bis(t-Butyl ester) can be used for conjugation of peptides and radionuclides.
|
-
- HY-W008201
-
|
|
Biochemical Assay Reagents
|
|
tert-Butyl 3-formylpyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W003177
-
|
|
Biochemical Assay Reagents
|
|
tert-Butyl 4-iodopiperidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W003140
-
|
|
Biochemical Assay Reagents
|
|
tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W101713
-
-
- HY-W250574
-
|
NOTA-bis(t-Butyl ester)
|
Chelators
|
|
NOTA-bis(tBu)ester (NOTA-bis(t-Butyl ester)), a NOTA derivative, is a bifunctional chelator that can be used for drug coupling .
|
-
- HY-W007500
-
|
|
Biochemical Assay Reagents
|
|
2,6-Di-Tert-butyl-4-methylpyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W003321
-
|
|
Biochemical Assay Reagents
|
|
(S)-tert-Butyl 5-oxopyrrolidine-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40146
-
|
N-Boc-3-azetidinone
|
Biochemical Assay Reagents
|
|
tert-Butyl 3-oxoazetidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W549538
-
|
|
Carbohydrates
|
|
tert-Butyl β-D-glucopyranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .
|
-
- HY-30120
-
|
|
Biochemical Assay Reagents
|
|
tert-Butyl N-[(1S,2S)-2-aminocyclohexyl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W777679
-
|
|
Carbohydrates
|
|
11-Maleimidoundecane-1-carbonyl-1-(t-butyl)carbazate is a biochemical assay reagent.
|
-
- HY-40174A
-
|
|
Biochemical Assay Reagents
|
|
tert-Butyl (2-aminoethyl)(methyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-76366
-
|
|
Biochemical Assay Reagents
|
|
(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W002421
-
|
|
Biochemical Assay Reagents
|
|
tert-butyl N-[(3R)-pyrrolidin-3-yl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W739814
-
-
- HY-W127622
-
|
3-(4-(tert-Butyl)pyridinio)-1-propanesulfonate
|
Surfactants
|
|
NDSB 256-4T is a non-washing sulfabetaine compound. NDSB-256-4T prevents protein aggregation and promotes protein folding by interacting with early folding intermediates .
|
| Cat. No. |
Product Name |
Target |
Research Area |
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-W016599
-
-
-
- HY-N7377
-
-
-
- HY-B1431
-
-
-
- HY-W014394
-
-
-
- HY-N11760
-
-
-
- HY-N9802
-
-
-
- HY-W010037
-
-
-
- HY-N10016
-
-
-
- HY-W024365R
-
|
|
Structural Classification
Monophenols
Source classification
Jatropha curcas Linn.
Phenols
Euphorbiaceae
Plants
|
PROTAC Linkers
|
|
3-tert-Butyl-4-methoxyphenol (Standard) is the analytical standard of 3-tert-Butyl-4-methoxyphenol. This product is intended for research and analytical applications. 3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .
|
-
-
- HY-N9702
-
-
-
- HY-W024365
-
-
-
- HY-W017140
-
-
-
- HY-N12344
-
-
-
- HY-N12299
-
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- HY-W010549R
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Structural Classification
Ketones, Aldehydes, Acids
Source classification
Endogenous metabolite
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Endogenous Metabolite
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3-tert-Butyl-4-methoxyphenol (Standard) is the analytical standard of 3-tert-Butyl-4-methoxyphenol. This product is intended for research and analytical applications. 3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .
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- HY-W014394R
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Structural Classification
Monophenols
other families
Source classification
Phenols
Plants
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TRP Channel
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Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
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- HY-N8445
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- HY-N9924
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- HY-W017140R
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- HY-N1506
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- HY-N1791
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- HY-N2996
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| Cat. No. |
Product Name |
Chemical Structure |
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- HY-B1431S
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Butylparaben-d4 is the deuterium labeled Butylparaben. Butylparaben is an organic compound, has proven to be a highly successful antimicrobial preservative in cosmetics, also used in medication suspensions, and as a flavoring additive in food.
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- HY-B1431S1
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Butylparaben- 13C6 is the 13C labeled Butylparaben . Butylparaben is an organic compound, has proven to be a highly successful antimicrobial preservative in cosmetics, also used in medication suspensions, and as a flavoring additive in food.
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- HY-B1431S2
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Butylparaben-d9 (Butyl parahydroxybenzoate-d9; Butyl paraben-d9) is a deuterium labeled Butylparaben (HY-B1431).
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- HY-B1430S
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Butamben-d9 is the deuterium labeled Butamben. Butamben (Butyl 4-aminobenzoate) results in long-lasting relief from pain, without impairing motor function or other sensory functions .
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- HY-17468S1
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Bumetanide-d5 Butyl Ester is the deuterium labeled Bumetanide Butyl Ester .
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- HY-W585914S
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2-(3-Sec-butyl-5-tert-butyl-2-hydroxyphenyl)benzotriazole-d4 is deuterium labeled 2-(3-Sec-butyl-5-tert-butyl-2-hydroxyphenyl)benzotriazole .
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- HY-W355238S
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Sec-butyl butyrate-d2 is deuterated labeled Sec-butyl butyrate.
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- HY-132350S
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iso-Nadolol (tert-Butyl-d9) is the deuterium labeled iso-Nadolol (tert-Butyl) .
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- HY-W017456S
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4-(tert-Butyl)aniline-d15 is the deuterium labeled 4-(tert-Butyl)aniline .
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- HY-151877S
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Ethyl N-n-Butyl-d9-carbamate is the deuterium labeled Ethyl N-n-Butyl-carbamate .
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- HY-76929S
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tert-Butyl 4-aminobenzoate- 13C6 is the 13C labeled tert-Butyl 4-aminobenzoate .
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- HY-128463S
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N-tert-Butyl-α-phenylnitrone-d14 is the deuterium labeled N-tert-Butyl-α-phenylnitrone . N-tert-Butyl-α-phenylnitrone is a nitrone-based free radical scavenger that forms nitroxide spin adducts. N-tert-Butyl-α-phenylnitrone inhibits COX2 catalytic activity. N-tert-Butyl-α-phenylnitrone has potent ROS scavenging, anti-inflammatory, neuroprotective, anti-aging and anti-diabetic activities, and can penetrate the blood-brain barrier .
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- HY-W011338S
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Benzyl butyl phthalate-d4 is the deuterium labeled Benzyl butyl phthalate . Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) .
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- HY-W010037S
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2-(tert-Butyl)-4-methoxyphenol-d3 is deuterium labeled 2-(tert-Butyl)-4-methoxyphenol.
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- HY-W024365S
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2-tert-Butyl-4-hydroxyanisole-d3 is deuterium labeled 3-tert-Butyl-4-methoxyphenol.
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- HY-W087240S
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1,3-Di-tert-butyl-5-iodobenzene-d3 is a deuterium labeled 1,3-Di-tert-butyl-5-iodobenzene.
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- HY-W017145S
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4-(tert-Butyl)benzene-1,2-diol-d12 is the deuterium labeled 4-(tert-Butyl)benzene-1,2-diol .
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- HY-W016730S
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tert-Butyl (1-hydroxypropan-2-yl)carbamate-d6 is the deuterium labeled tert-Butyl (1-hydroxypropan-2-yl)carbamate .
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- HY-W010216S
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4-(tert-Butyl)cyclohexanone-d9 is the deuterium labeled 4-(tert-Butyl)cyclohexanone .
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- HY-W011565S1
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3,6-Di-tert-butyl-9H-carbazole-d25 is a deuterium labeled 3,6-Di-tert-butyl-9H-carbazole.
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- HY-W011565S
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3,6-Di-tert-butyl-9H-carbazole-d6 is the deuterium labeled 3,6-Di-tert-butyl-9H-carbazole.
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- HY-W283336S
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2,5-Di-(tert-butyl)-4-methoxyphenol-3,6-d20 is the deuterium labeled 2,5-Di-tert-butyl-4-methoxyphenol .
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- HY-W077436S
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2,6-Di-(tert-butyl)-4-methoxyphenol-3,5-d20 is the deuterium labeled 2,6-Di-tert-butyl-4-methoxyphenol .
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- HY-32208S
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tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate-d4 is the deuterium labeled tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate[1].
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- HY-W454945S
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tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8 is the deuterium labeled tert-Butyl piperazine-1-carboxylate .
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- HY-W440436S
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2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(tert-butyl)phenol-d4 is deuterium labeled 2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(tert-butyl)phenol .
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- HY-W454729S
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tert-Butyl 4-hydroxypiperidine-1-carboxylate-3,3,4,5,5-d5 is the deuterium labeled tert-Butyl 4-hydroxypiperidine-1-carboxylate .
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- HY-W011886S
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N2-(tert-Butyl)-N4-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine-d9 is the deuterium labeled N2-(tert-Butyl)-N4-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine .
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- HY-Y1169S2
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Fmoc-Asp(OtBu)-OH-d3 (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d3) is deuterium labeled Fmoc-Asp(OtBu)-OH. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
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- HY-W017140S
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2-Sec-butyl-3-methoxypyrazine-d3 is deuterated labeled cis-?Jasmone (HY-N7058). Cis-Jasmone is a plant-derived natural product. Cis-Jasmone is constitutively released by many flowers and sometimes by leaves as an attractant for pollinators or as a chemical cue for host location by insect flower herbivores. Cis-Jasmone treatment of crop plants not only induces direct defense against herbivores, but also induces indirect defense by releasing VOCs that attract natural enemies .
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- HY-W102278S
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Tinuvin-327-d3 (2,4-Di-tert-Butyl-6-(5-chloro-2H-benzotriazol-2-yl)phenol-d3 (UV-327-d3)) is deuterium labeled 2,4-Di-tert-butyl-6-(5-chloro-2H-benzo[d][1,2,3]triazol-2-yl)phenol .
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- HY-141902S
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FMOC-L-Glutamic Acid- 13C5, 15N-5-t-butyl ester is the 13C and 15N labeled FMOC-L-Glutamic Acid-5-t-butyl ester .
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- HY-152040S
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Tenuazonic acid-(acetyl- 13C2) (mixture of diastereomers) in methanol (3-(Acetyl- 13C2)-5-((S)-sec-butyl)-4-hydroxy-1,5-dihydro-2H-pyrrol-2-one) is 13C labeled Tenuazonic acid-(acetyl) (mixture of diastereomers) in methanol .
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- HY-A0052S
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(1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide-d4 is deuterated labeled (1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide.
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- HY-W714205S
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Desethyl terbumeton-d3 is deuterium labeled N2-(Tert-butyl)-6-methoxy-1,3,5-triazine-2,4-diamine .
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- HY-W343292S1
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2-Methylbutyl acetate-d3 is deuterated labeled 2-Methylbutyl acetate.
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- HY-Y1169S1
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Fmoc-Asp(OtBu)-OH- 13C4, 15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH . Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
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- HY-W343292S
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2-Methylbutyl acetate- 13C2 is 13C labeled 2-Methylbutyl acetate.
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| Cat. No. |
Product Name |
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Classification |
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- HY-W451440
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Alkynes
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Butyne-DOTA-tris(t-butyl ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. Butyne-DOTA-tris(t-butyl ester) can be used for conjugation of peptides and radionuclides.
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- HY-W457953
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Azide
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tert-Butyl N-(4-azidobutyl)carbamate is N-Boc protected crosslinker. tert-Butyl N-(4-azidobutyl)carbamate can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-W749614
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Alkynes
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NO2A-Butyne-bis(t-Butyl ester)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. NO2A-Butyne-bis(t-Butyl ester) can be used for conjugation of peptides and radionuclides.
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- HY-151772
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Tetrazine
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Methyltetrazine-PEG12-t-butyl ester is a monodisperse PEG compound. Methyltetrazine-PEG12-t-butyl ester is a click chemistry reagent containing a tetrazine group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .
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- HY-132062
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PROTAC Synthesis
Azide
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Azido-PEG11-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG11-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140783
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Azide
PROTAC Synthesis
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Azido-PEG15-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG15-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-132061
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Azide
PROTAC Synthesis
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Azido-PEG14-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG14-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-132060
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Azide
PROTAC Synthesis
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Azido-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG7-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140753
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PROTAC Synthesis
Azide
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DOTA-(t-butyl)3-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DOTA-(t-butyl)3-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151792
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Azide
PROTAC Synthesis
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Pomalidomid-C6-PEG3-butyl-N3 is a click chemistry reagent containing an azide group. Pomalidomid-C6-PEG3-butyl-N3 also is a crosslinker-E3 ligase ligand conjugate, which be used in click reactive protein degrader building block for PROTAC research.
Pomalidomid-C6-PEG3-butyl-N3 also can be used in the template for synthesis of targeted protein degrader . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-140592
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Azide
PROTAC Synthesis
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Azido-PEG3-S-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-S-PEG4-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140094
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Alkynes
PROTAC Synthesis
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N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140564
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PROTAC Synthesis
Azide
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N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG3-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140873
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PROTAC Synthesis
Azide
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N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140870
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PROTAC Synthesis
Azide
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N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-151791
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Azide
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(S,R,S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent containing an azide group. (S,R,S)-AHPC-C6-PEG3-butyl-N3 serves as crosslinker-E3 ligase ligand conjugate, Click reactive protein degrader building block for PROTAC research, Template for synthesis of targeted protein degrader, VH032 conjugate . (S,R,S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-W598193
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Azide
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[(5-Azidopentyl)oxy](tert-butyl)dimethylsilane is a silane compound with a terminal azide group. The trimethylsilane is commonly used for surface modifications. The terminal azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry.
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- HY-140032
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Alkyne-ethyl-PEG1-t-Butyl ester
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Alkynes
PROTAC Synthesis
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Alkyne-ethyl-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Alkyne-ethyl-PEG1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140791
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17-(Azide-PEG9-ethylcarbamoyl)heptadecanoic t-Butyl ester
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PROTAC Synthesis
Azide
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Azide-PEG9-amido-C16-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C16-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140788
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5-(Azide-PEG9-ethylcarbamoyl)pentanoic t-Butyl ester
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Azide
PROTAC Synthesis
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Azide-PEG9-amido-C4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140787
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17-(Azide-PEG6-ethylcarbamoyl)heptadecanoic t-Butyl ester
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PROTAC Synthesis
Azide
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Azide-PEG6-amido-C16-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG6-amido-C16-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140789
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9-(Azide-PEG9-ethylcarbamoyl)nonanoic t-Butyl ester
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Azide
PROTAC Synthesis
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Azide-PEG9-amido-C8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C8-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140790
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13-(Azide-PEG9-ethylcarbamoyl)tridecanoic t-Butyl ester
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Azide
PROTAC Synthesis
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Azide-PEG9-amido-C12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG9-amido-C12-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-114402
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PROTAC Synthesis
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ARD-69 is a PROTAC degrader based on the E3 ubiquitin ligase VHL and targeting the androgen receptor, which can induce androgen receptor (AR) protein degradation in AR-positive prostate cancer cells. ARD-69 inhibits AR-regulated gene expression, binds to the AR ligand binding domain at one end and binds to VHL at the other end, prompting AR to be recruited to the E3 ubiquitin ligase complex, triggering proteasome degradation, thereby inhibiting AR signaling pathways and downstream gene expression (such as PSA, TMPRSS2). ARD-69 can be used to study the treatment of castration-resistant prostate cancer (mCRPC) .
ARD-69 is composed of a target protein ligand (pink part) AR antagonist 14 (HY-172624), a PROTAC linker (black part) tert-Butyl 4-ethynyl-[1,4'-bipiperidine]-1'-carboxylate (HY-W442074), and a VHL-type E3 ubiquitinase ligand (blue part) VH 101, acid (HY-47070); among them, the VHL ligand and the linker can form a conjugate VH 101-amide-piperidine-Pip-alkyne (HY-172625).
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| Cat. No. |
Product Name |
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Classification |
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- HY-B1431
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Butyl parahydroxybenzoate; Butyl paraben; Butyl 4-hydroxybenzoate
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Sweetening Agents
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Butylparaben is an organic compound that has proven to be a very successful antimicrobial preservative in cosmetics, can also be used in active molecule suspensions, and as a food flavoring additive .
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- HY-W800843
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Cationic Lipids
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tert-Butyl 3-(7-((undecan-3-yloxy)carbonyl)heptylamino)propylcarbamate is an aminolipid featuring a Boc-protected primary amine, a propylamine spacer attached to an octanoate chain and a C11 chain.
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- HY-152333
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Nucleosides and their Analogs
G
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7-n-Butyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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