2. Gene
  3. Pnp - purine nucleoside phosphorylase Gene

Pnp - purine nucleoside phosphorylase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Np

Gene ID: 290029 | Gene type: protein coding

About Pnp

Summary

Enables purine-nucleoside phosphorylase activity. Involved in purine nucleoside metabolic process. Located in cytoplasm; extracellular region; and nucleus. Human ortholog(s) of this gene implicated in purine nucleoside phosphorylase deficiency and purine-pyrimidine metabolic disorder. Orthologous to human PNP (purine nucleoside phosphorylase). [provided by Alliance of Genome Resources, Apr 2022]

Pnp Products(1)

mRNA Protein Name
NM_001399678.1 NP_001386607.1 purine nucleoside phosphorylase
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables purine-nucleoside phosphorylase activity IDA
IDA: Inferred from direct assay
1834379 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular region IDA
IDA: Inferred from direct assay
15532538 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

purine nucleoside phosphorylase

inosine phosphorylase

inosine-guanosine phosphorylase

nucleoside phosphorylase

Related Agents

Approval
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-16209 Forodesine hydrochloride 99.86% Yes
HY-16210 Forodesine 99.88% Yes
HY-W011727A Pyridoxal 5'-​phosphate monohydrate ≥98.0% Unkown
HY-W011727 Pyridoxal 5'-phosphate hydrate 99.76% Unkown
Clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-19480 Ulodesine 99.00% Phase 2
HY-106934A Peldesine dihydrochloride Inhibitor 99.63% Phase 1
HY-106934 Peldesine Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (98)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-20336 Mc-Val-Cit-PABC-PNP 98.89% Unkown
HY-41189 Fmoc-Val-Cit-PAB-PNP 98.99% Unkown
HY-136329 β-D-glucuronide-pNP-carbonate 99.44% Unkown
HY-130777A AMP-PNP lithium hydrate ≥94.0% Unkown
HY-W008638 2'-Deoxyinosine 99.83% Unkown
HY-136136 Fmoc-Val-Ala-PAB-PNP 98.90% Unkown
HY-141142 Boc-Val-Cit-PAB-PNP 99.55% Unkown
HY-112835 Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside 99.42% Unkown
HY-128933 AMP-PNP tetralithium Inhibitor ≥97.0% Unkown
HY-137827 4-Nitrophenyl β-D-Cellobioside 99.48% Unkown
HY-140150 Azido-PEG3-Val-Cit-PAB-PNP 99.09% Unkown
HY-136154 Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP 96.67% Unkown
HY-P2724 Purine nucleoside phosphorylase, Microorganism / Unkown
HY-130937 DBCO-Val-Cit-PABC-PNP 96.54% Unkown
HY-139362 Enpp-1-IN-2 Inhibitor 99.16% Unkown
HY-148425 Mal-amide-PEG8-Val-Ala-PAB-PNP 99.60% Unkown
HY-W039442 2′-Deoxy-2′-fluoroadenosine 99.71% Unkown
HY-135975 MC-Val-Ala-PAB-PNP 99.51% Unkown
HY-130932 Boc-Val-Ala-PAB-PNP ≥98.0% Unkown
HY-140145 Mal-PEG4-Val-Cit-PAB-PNP 97.05% Unkown
HY-W039911 4-Nitrophenyl α-D-galactopyranoside 98.70% Unkown
HY-140147 Mal-amido-PEG2-Val-Cit-PAB-PNP 98.40% Unkown
HY-147164 MC-Gly-Gly-Phe-Gly-PAB-PNP 98.75% Unkown
HY-148461 Mal-VC-PAB-PNP 96.86% Unkown
HY-114430 Fmoc-Phe-Lys(Boc)-PAB-PNP 98.67% Unkown
HY-W011727S Pyridoxal Phosphate-d3 98.01% Unkown
HY-131156 Mal-PEG2-Val-Cit-PABA-PNP 96.82% Unkown
HY-121106 9-Deazaguanine 99.18% Unkown
HY-129350 Fmoc-Phe-Lys(Trt)-PAB-PNP ≥98.0% Unkown
HY-147021 MC-Val-D-Cit-PAB-PNP / Unkown
HY-W008638R 2'-Deoxyinosine (Standard) / Unkown
HY-129352 Cbz-Phe-(Alloc)Lys-PAB-PNP / Unkown
HY-118047 CI 972 anhydrous Inhibitor / Unkown
HY-129351 Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP / Unkown
HY-129353 Boc-Phe-(Alloc)Lys-PAB-PNP / Unkown
HY-129361 Fmoc-Ala-Ala-Asn-PABC-PNP / Unkown
HY-130777 AMP-PNP / Unkown
HY-134354 pNP-ADPr / Unkown
HY-134354A pNP-ADPr disodium 99.93% Unkown
HY-134420 p-Nitrophenyl α-L-fucoside / Unkown
HY-136100 TCO-PEG1-Val-Cit-PABC-PNP / Unkown
HY-136105 Azido-PEG1-Val-Cit-PABC-PNP / Unkown
HY-136108 Fmoc-Gly3-Val-Cit-PAB-PNP / Unkown
HY-139247 pNPS-DHA / Unkown
HY-139856 Mal-Ala-Ala-PAB-PNP / Unkown
HY-140144 Mal-PEG1-Val-Cit-PAB-PNP 98.41% Unkown
HY-141145 OPSS-Val-Cit-PAB-PNP / Unkown
HY-144628 Fmoc-Asn-Pro-Val-PABC-PNP / Unkown
HY-147021A MC-D-Val-Cit-PAB-PNP / Unkown
HY-148031 MC-Ala-Ala-Asn-PAB-PNP / Unkown
HY-148399 Mal-VC-PAB-PNP-CDN-A / Unkown
HY-153486 N3-VC-PAB-PNP 97.35% Unkown
HY-158199 BCN-HS-PEG2-bis(PNP) / Unkown
HY-160703 DMBA-SIL-PNP / Unkown
HY-173161 Mc-d-Val-d-Cit-PAB-PNP / Unkown
HY-20336G Mc-Val-Cit-PABC-PNP (GMP) / Unkown
HY-P2724A Purine nucleoside phosphorylase, Bacillus sp. / Unkown
HY-RS10789 PNP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W145529 GalNAcβ(1-3)Galα(1-4)Galβ(1-4)Glc-β-pNP / Unkown
HY-W145534 GlcNAcβ(1-3)GalNAc-α-pNP / Unkown
HY-W145540 Galβ(1-3)[Neu5Acα(2-6)]GalNAc-α-pNP / Unkown
HY-W145553 GalNAcβ(1-3)GlcNAc-β-pNP / Unkown
HY-W145556 Galβ(1-3)GlcNAcβ(1-3)Galβ(1-4)Glc-β-pNP / Unkown
HY-W145607 Galβ(1-3)GalNAc-β-pNP / Unkown
HY-W145622 Galβ(1-3)[Neu5Acα(2-6)]GlcNAc-β-pNP / Unkown
HY-W145631 GalNAcβ(1-4)GlcNAc-β-pNP / Unkown
HY-W357155 Gal1-β-3GlcNAc-β-PNP / Unkown
HY-W698379 Gal1-b-4GlcNAc-α-PNP / Unkown
HY-W698411 GlcNAc1-β-6GalNAc-α-PNP / Unkown
HY-W699180 Fuc1-α-2Gal1-β-3GlcNAc-β-PNP / Unkown
HY-W800847 Mal-Amide-PEG4-Val-Cit-PAB-PNP / Unkown
HY-137828 4-Nitrophenyl N,N′-diacetyl-β-D-chitobioside / Unkown
HY-137878 2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid / Unkown
HY-141153 Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP / Unkown
HY-151699 6-Azidohexanoyl-Val-Cit-PAB-PNP / Unkown
HY-151726 Azido-PEG(4)-Val-Cit-PAB-PNP / Unkown
HY-151740 4-Pentynoyl-Val-Ala-PAB-PNP / Unkown
HY-160790 β-Glu-PNP / Unkown
HY-172291 Mal-amide-PEG8-Val-Cit-PAB-PNP / Unkown
HY-20560 (Ac)Phe-Lys(Alloc)-PABC-PNP / Unkown
HY-W015996 4-Nitrophenyl-N-acetyl-α-D-galactosaminide / Unkown
HY-W190913 DBCO-PEG4-Val-Cit-PAB-PNP / Unkown
HY-W395122 Mal-PEG1-PNP-carbonate / Unkown
HY-W591286 Alkyne-Val-Cit-PAB-PNP / Unkown
HY-W591336 Alloc-Val-Ala-PAB-PNP / Unkown
HY-W591374 DBCO-PEG4-Val-Ala-PAB-PNP / Unkown
HY-W591439 Fmoc-Lys(Boc)-PAB-PNP / Unkown
HY-W591440 Fmoc-Cit-PAB-PNP / Unkown
HY-W591441 Fmoc-Ala-PAB-PNP / Unkown
HY-W800617 NH2-PEG1-Val-Cit-PAB-OH / Unkown
HY-W800618 NH2-PEG3-Val-Cit-PAB-OH / Unkown
HY-W800619 NH2-PEG4-Val-Cit-PAB-OH / Unkown
HY-W800620 NH2-PEG6-Val-Cit-PAB-OH / Unkown
HY-W800621 Fmoc-PEG2-Val-Cit-PAB-OH / Unkown
HY-W800622 Fmoc-PEG4-Val-Cit-PAB-OH / Unkown
HY-W800623 Fmoc-PEG6-Val-Cit-PAB-OH / Unkown
HY-W800624 Boc-PEG2-Val-Cit-PAB-OH / Unkown
HY-W800625 Boc-PEG4-Val-Cit-PAB-OH / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pnp NCBI NCBI:4860
Macaca fascicularis Pnp NCBI NCBI:102146459
Mus musculus Pnp NCBI NCBI:18950