2. Gene
  3. BRD4 - bromodomain containing 4 Gene

BRD4 - bromodomain containing 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa
Gene ID: 100533540 | Gene type: protein coding

About BRD4

Primary_assembly 2: 62,250,989-62,345,362 forward strand.Sscrofa11.1:CM000813.5

This gene has 3 transcripts (splice variants), 66 orthologues and 11 paralogues. Ubiquitous expression in ovary (RPKM 2.2), spleen (RPKM 15.3) and 8 other tissues.

BRD4 Products(1)

mRNA Protein Name
NM_001204772.1 NP_001191701.1 bromodomain-containing protein 4

BRD4 Protein Structure

Bromo_Brdt_I_like

Bromo_Brdt_I_like: cd05497 (57 - 163)

Bromo_Brdt_II_like

Bromo_Brdt_II_like: cd05498 (352 - 453)

BET

BET: pfam17035 (608 - 672)

PHA03247

PHA03247: cl33720 (814 - 1236)

TPH

TPH: cl38442 (1270 - 1313)

BRD4_CDT

BRD4_CDT: pfam17105 (1362 - 1405)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1406 a.a.
Protein Preferred Names Protein Names

bromodomain-containing protein 4

bromodomain containing protein 4

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-111916 ODM-207 Inhibitor 99.58% Phase 2
HY-112090 ABBV-744 Inhibitor 99.95% Phase 1
Pre-clinical Phase
Bioactive Molecules (132)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100972 ARV-771 Inhibitor 99.87% Unkown
HY-101838 dBET1 Inhibitor 99.24% Unkown
HY-12863 Pelabresib Inhibitor 99.95% Unkown
HY-136570 GSK778 Inhibitor 98.93% Unkown
HY-122826 ZXH-3-26 Inhibitor 98.90% Unkown
HY-123941 FKBP12 PROTAC dTAG-7 Inhibitor 99.07% Unkown
HY-100482 CPI-637 Inhibitor 99.94% Unkown
HY-14443 XMD8-92 Inhibitor 99.48% Unkown
HY-136571 GSK046 Inhibitor 99.65% Unkown
HY-114305 A1874 Inhibitor 99.70% Unkown
HY-129937A GNE-987 Inhibitor 99.91% Unkown
HY-107443 I-BET762 carboxylic acid Inhibitor 99.55% Unkown
HY-120028 GNE-207 Inhibitor 99.94% Unkown
HY-19999A PF-CBP1 hydrochloride Inhibitor 99.96% Unkown
HY-123844 dBET57 Inhibitor 99.94% Unkown
HY-141438 SIM1 Inhibitor 99.57% Unkown
HY-110374 NVS-CECR2-1 Inhibitor 99.40% Unkown
HY-101146 SF2523 Inhibitor 98.25% Unkown
HY-101519 BETd-260 Inhibitor 99.59% Unkown
HY-112609 QCA570 Inhibitor 99.95% Unkown
HY-103632 PROTAC BRD9 Degrader-1 Inhibitor 99.16% Unkown
HY-156828 MMH2 Degrader 98.95% Unkown
HY-125232 MS645 ≥98.0% Unkown
HY-138563 GSK973 Inhibitor 99.97% Unkown
HY-114204 GSK8814 Inhibitor 99.80% Unkown
HY-126428 ZL0580 Modulator 99.26% Unkown
HY-114504 RVX-297 Inhibitor 95.00% Unkown
HY-112429 HJB97 Inhibitor 98.05% Unkown
HY-160528 IBG3 Inhibitor 98.53% Unkown
HY-133737 PROTAC BRD4 Degrader-5 Inhibitor 99.93% Unkown
HY-111102 FL-411 Inhibitor 99.05% Unkown
HY-133131 PROTAC BRD4 Degrader-1 Inhibitor 99.12% Unkown
HY-107442 PROTAC BRD4-binding moiety 1 99.14% Unkown
HY-129917 KB02-JQ1 Inhibitor 99.17% Unkown
HY-117491 BRD4 Inhibitor-10 Inhibitor 99.52% Unkown
HY-136920 CBP/p300-IN-8 Inhibitor 99.94% Unkown
HY-161515 BRD4/NAMPT-IN-1 Inhibitor 99.45% Unkown
HY-148864 JQ1-TCO Inhibitor 99.95% Unkown
HY-120000 MS402 Inhibitor 99.62% Unkown
HY-112610 CF53 Inhibitor 99.81% Unkown
HY-130622 LT052 Inhibitor 98.77% Unkown
HY-156827 MMH1 Degrader 98.08% Unkown
HY-136857 BRD4 degrader-3 Degrader 99.43% Unkown
HY-145260 BRD4/CK2-IN-1 Inhibitor 98.21% Unkown
HY-158031 PLK1/BRD4-IN-5 Inhibitor 99.55% Unkown
HY-146208 BRD4 Inhibitor-20 Inhibitor 99.00% Unkown
HY-147202 BRD4 Inhibitor-24 Inhibitor 99.27% Unkown
HY-112376 MZP-54 Inhibitor 98.16% Unkown
HY-101121 NI-42 Inhibitor 99.53% Unkown
HY-131061 BET bromodomain inhibitor 1 Inhibitor 99.91% Unkown
HY-111502 Y06036 Inhibitor 98.57% Unkown
HY-139148 UMB298 Inhibitor 99.28% Unkown
HY-146999 YM458 Inhibitor 99.16% Unkown
HY-129201 ZEN-2759 Inhibitor 99.51% Unkown
HY-148864A (Z)-JQ1-TCO Inhibitor 99.34% Unkown
HY-163638 BRD4 degrader-1 Degrader 99.85% Unkown
HY-111875 SNIPER(BRD)-1 Inhibitor 99.43% Unkown
HY-145264 OARV-771 Inhibitor 98.33% Unkown
HY-142520 I-BET567 Inhibitor 99.49% Unkown
HY-114416 GS-626510 Inhibitor 99.80% Unkown
HY-103297 OXFBD02 Inhibitor 98.04% Unkown
HY-160558 PLK1/BRD4-IN-3 Inhibitor 99.66% Unkown
HY-160557 PLK1/BRD4-IN-2 Inhibitor / Unkown
HY-111503 Y06137 Inhibitor 99.90% Unkown
HY-132991 ML 2-14 Degrader 99.43% Unkown
HY-107425A cis-MZ 1 Degrader / Unkown
HY-111977 ZEN-3219 Inhibitor 99.75% Unkown
HY-114407 TD-428 Inhibitor 98.81% Unkown
HY-161651 BRD4 ligand 6 / Unkown
HY-110215 XD14 Inhibitor 95.02% Unkown
HY-135236 OXFBD04 Inhibitor 98.99% Unkown
HY-133136 PROTAC BRD4 Degrader-2 Inhibitor / Unkown
HY-126325 BY27 Inhibitor / Unkown
HY-146660 BRD4 Inhibitor-18 Inhibitor / Unkown
HY-102044 BET-IN-2 Inhibitor / Unkown
HY-136794 SB-284851-BT Inhibitor / Unkown
HY-157460 BRD4 Inhibitor-29 / Unkown
HY-104072 BRD4-IN-3 Inhibitor / Unkown
HY-162240 SJH1-51B Degrader / Unkown
HY-131203 PROTAC BRD4 Degrader-6 Inhibitor / Unkown
HY-172827 PROTAC BRD4 Degrader-30 Degrader / Unkown
HY-173327 BRD4 degrader-6 Degrader / Unkown
HY-129937 (S)-GNE-987 Inhibitor / Unkown
HY-169358 L134 Inhibitor / Unkown
HY-172124 PROTAC BRD4 Degrader-29 Degrader / Unkown
HY-143235 BRD4 Inhibitor-15 Inhibitor / Unkown
HY-163413 BRD4-BD1-IN-3 Inhibitor / Unkown
HY-168634 SJ46421 Inhibitor / Unkown
HY-139294 PROTAC BRD4 Degrader-15 Inhibitor / Unkown
HY-170686 BRD4 Inhibitor-38 Inhibitor / Unkown
HY-143328 PROTAC BRD4 Degrader-17 Degrader / Unkown
HY-173062 BRD4 Inhibitor-40 Inhibitor / Unkown
HY-143471 WNY0824 Inhibitor / Unkown
HY-150683 NC-III-49-1 Inhibitor / Unkown
HY-149806 Bromodomain IN-2 Inhibitor / Unkown
HY-135558 PROTAC BRD4 Degrader-3 Inhibitor / Unkown
HY-143299 BRD4-BD1-IN-1 Inhibitor / Unkown
HY-149100 PLK1-IN-6 Inhibitor / Unkown
HY-147374 Bromodomain inhibitor-9 Inhibitor / Unkown
HY-153945 BET-IN-15 Inhibitor / Unkown
HY-152213 BET-IN-13 Inhibitor / Unkown
HY-111978 ZEN-3862 Inhibitor 98.86% Unkown
HY-150684 GXH-II-052 Inhibitor / Unkown
HY-W265951 3-Methylcarbostyril Inhibitor / Unkown
HY-130612 PROTAC BRD2/BRD4 degrader-1 Inhibitor / Unkown
HY-147375 Bromodomain inhibitor-10 Inhibitor / Unkown
HY-160662 BRD4-IN-5 Inhibitor / Unkown
HY-169170 PARP1/BRD4-IN-3 Inhibitor / Unkown
HY-170380 XY221 Inhibitor / Unkown
HY-170390 AB3067 Degrader / Unkown
HY-157290 HL403 Inhibitor / Unkown
HY-155680 BET BD2-IN-1 Inhibitor / Unkown
HY-142705 BRD4 D1-IN-2 Inhibitor / Unkown
HY-153519 WWL0245 Inhibitor / Unkown
HY-173433 JV8 Degrader / Unkown
HY-111979 ZEN-3411 Inhibitor / Unkown
HY-100696 PNZ5 Inhibitor / Unkown
HY-163639 BRD4 degrader-2 Inhibitor / Unkown
HY-151972 BRD4 Inhibitor-25 Inhibitor / Unkown
HY-132128 BRD4 Inhibitor-12 Inhibitor / Unkown
HY-161650 PROTAC BRD4 Degrader-26 Degrader / Unkown
HY-144338 PARP1/BRD4-IN-1 Inhibitor / Unkown
HY-150613 PARP1/BRD4-IN-2 Inhibitor / Unkown
HY-149098 SJ1461 Inhibitor / Unkown
HY-158331 Gal-ARV-771 Degrader / Unkown
HY-143300 BRD4-BD1-IN-2 Inhibitor / Unkown
HY-163282 NB512 Inhibitor / Unkown
HY-172130 PI3Kδ/BET-IN-1 Inhibitor / Unkown
HY-161368 BRD-SF2 Degrader / Unkown
HY-155222 TW9 Inhibitor / Unkown
HY-132130 BRD4 Inhibitor-13 Inhibitor / Unkown
HY-136570A GSK778 hydrochloride Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens BRD4 NCBI NCBI:23476