2. PROTAC Epigenetics
  3. PROTACs Epigenetic Reader Domain
  4. PROTAC BRD4 Degrader-36

PROTAC BRD4 Degrader-36 is a BRD4 PROTAC degrader. PROTAC BRD4 Degrader-36 has a DC50 of 0.649 nM and a Dmax of 71% in PANC-1 cells. PROTAC BRD4 Degrader-36 is cytotoxic to PANC-1 cells (GI50: 0.103 μM). PROTAC BRD4 Degrader-36 can be used in the study of cancer. (Pink: PROTAC BRD4 ligand-1 (HY-129939); Blue + Black: E3 ligase ligand + linker (HY-175241)).

For research use only. We do not sell to patients.

PROTAC BRD4 Degrader-36

PROTAC BRD4 Degrader-36 Chemical Structure

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PROTAC BRD4 Degrader-36 Related Antibodies

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

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Description

PROTAC BRD4 Degrader-36 is a BRD4 PROTAC degrader. PROTAC BRD4 Degrader-36 has a DC50 of 0.649 nM and a Dmax of 71% in PANC-1 cells. PROTAC BRD4 Degrader-36 is cytotoxic to PANC-1 cells (GI50: 0.103 μM). PROTAC BRD4 Degrader-36 can be used in the study of cancer. (Pink: PROTAC BRD4 ligand-1 (HY-129939); Blue + Black: E3 ligase ligand + linker (HY-175241))[1].

IC50 & Target[1]

BRD4

 

Molecular Weight

1013.24

Formula

C52H58F2N6O7S3
SMILES

O=C(C1=C(C=C2C3=CN(C(C4=C3C(CN(C2=C1)C5=NC=C(C=C5F)F)=CN4)=O)C)CS(C)(=O)=O)NCCCCCCCN(CC6CCCCC6)C(C7=C(S(=O)(C)=O)C=C(C=C7)C8=CC=CC=C8SC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PROTAC BRD4 Degrader-36 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC BRD4 Degrader-36PROTACsEpigenetic Reader DomainPANC-1 cellsInhibitorinhibitorinhibit

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