2. Epigenetics Protein Tyrosine Kinase/RTK
  3. Epigenetic Reader Domain Src
  4. HL403

HL403 is a potent and dual BRD4/Src inhibitor. HL403 has IC50 values of 133 nM for BRD4 inhibition and 4.5 nM for Src inhibition. HL403 shows anti-cancer activity.

For research use only. We do not sell to patients.

HL403

HL403 Chemical Structure

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HL403 Related Antibodies

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Lck Fyn Blk Hck Lyn Yes SRC-3

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Description

HL403 is a potent and dual BRD4/Src inhibitor. HL403 has IC50 values of 133 nM for BRD4 inhibition and 4.5 nM for Src inhibition. HL403 shows anti-cancer activity[1].

IC50 & Target

BRD4

133 nM (IC50)

Molecular Weight

941.95

Formula

C44H46Cl2N12O4S2
SMILES

CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@H](C4=NN=C(N42)C)CC(N[C@@H](C)C(OCCN5CCN(CC5)C6=NC(C)=NC(NC7=NC=C(S7)C(NC8=C(C=CC=C8Cl)C)=O)=C6)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HL403 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HL403HL 403HL-403Epigenetic Reader DomainSrcMDA-MB-231Triple-negative breast cancerTNBCInhibitorinhibitorinhibit

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HL403
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HY-157290
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