Search Result
Results for "
short peptide
" in MedChemExpress (MCE) Product Catalog:
4
Biochemical Assay Reagents
1
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-P1563
-
-
-
- HY-126488
-
-
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- HY-W736950A
-
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Amino Acid Derivatives
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Others
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H-L-Cys(MDNPE)-OH hydrochloride is a cysteine derivative with a short peptide sequence attached to the thiol group of cysteine.
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-
-
- HY-P3526
-
-
-
- HY-P1512
-
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SOD
|
Cancer
|
Antioxidant peptide A is a short peptide, which contains alternative aromatic or sulfur-containing amino acid. The side chains of Antioxidant peptide A are believed to contribute to strong radical scavenging activities of peptides in the cancer cell.
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-
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- HY-P3326
-
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Bacterial
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Infection
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Targeting the bacterial sliding clamp peptide 46 is a short peptide targeting the bacterial sliding clamp(SC), inhibiting SC-dependent DNA synthesis.
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-
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- HY-103303
-
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CGRP Receptor
|
Metabolic Disease
|
CRSP-1 is short for calcitonin receptor-stimulating peptide-1. CRSP-1 inhibits osteoclast formation by inhibiting the formation and activity of multinucleated osteoclast .
|
-
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- HY-P1593
-
-
-
- HY-P1734
-
|
PKC
|
Neurological Disease
|
Ac-MBP 1-11, a short peptide sequence, is the major encephalitogenic epitope in myelin basic protein (MBP) .
|
-
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- HY-134578
-
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Drug Intermediate
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Others
|
H-Arg-Ser-Arg-OH is a short peptide. H-Arg-Ser-Arg-OH is a motif of di-leucine and RSRR, it can be used to design larger peptides and compound .
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-
-
- HY-P1593A
-
-
-
- HY-P10709
-
|
Biochemical Assay Reagents
|
Cardiovascular Disease
Cancer
|
CREKA peptide is a short peptide sequence, belonging to self-assembling peptides (SAPs), which can self-assemble into functional nanostructures, typically nanofibers, under physiological conditions. CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity .
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- HY-P10709A
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Biochemical Assay Reagents
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Cardiovascular Disease
Cancer
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CREKA peptide acetate is a short peptide sequence, belonging to self-assembling peptides (SAPs), which can self-assemble into functional nanostructures, typically nanofibers, under physiological conditions. CREKA peptide acetate can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity .
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-
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- HY-P3321A
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-
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- HY-P2299
-
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HPV
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Cancer
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Protein E7(43-62) is an E7-derived peptide with anti-tumor effects (short peptide spanning the 43th to 62th amino acid residues in the E7 protein) .
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-
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- HY-151496
-
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Others
|
Others
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H-Cys-Val-2-Nal-Met-OH is a peptide. H-Cys-Val-2-Nal-Met-OH is a peptidomimetic derivative that can be used to label short peptide sequences .
|
-
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- HY-P10739
-
|
MMP
|
Inflammation/Immunology
|
WYRGRL, a collagen II-targeting peptide, can bind to collagen II α1. WYRGRL is a short cartilage-targeting peptide sequence. WYRGRL leads to about 72-fold increase of cartilage-targeting efficiency for the peptide-functionalized nanoplatform in vivo .
|
-
-
- HY-P2299A
-
|
HPV
|
Cancer
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Protein E7(43-62) TFA is an E7-derived peptide with anti-tumor effects (short peptide spanning the 43th to 62th amino acid residues in the E7 protein) .
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-
-
- HY-P3302
-
|
Biochemical Assay Reagents
|
Others
|
Sialylglycopeptide is a complex N-glycan, bearing a short peptide fragment. Sialylglycopeptide, as a starting material for the semi-synthesis of N-glycans, can be used for various researches .
|
-
-
- HY-P10705
-
|
Biochemical Assay Reagents
|
Cancer
|
KGFRWR is a short peptide sequence, belonging to self-assembling peptides (SAPs), which can self-assemble into functional nanostructures, typically nanofibers, under physiological conditions. KGFRWR can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity .
|
-
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- HY-P10541
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HSP
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Others
|
HSP70/DnaK substrate peptide is a short peptide that the HSP70/DnaK molecular chaperone can bind and act on. HSP70/DnaK substrate peptide can be used to study the mechanism of action of HSP70/DnaK in molecular chaperone function .
|
-
-
- HY-P3291
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ZP7570
|
GCGR
|
Metabolic Disease
|
Dapiglutide (ZP7570) is a long-acting glucagon-like peptide-1 receptor 1R (GLP-1R)/Glucagon-like peptide-2 receptor (GLP-2R) dual agonist. Dapiglutide alleviates intestinal dysfunction in a mouse short bowel model and has anti-obesity effects .
|
-
-
- HY-103276
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-
-
- HY-126488R
-
|
Endogenous Metabolite
|
Metabolic Disease
|
H-Ser-His-OH (Standard) is the analytical standard of H-Ser-His-OH. This product is intended for research and analytical applications. H-Ser-His-OH is a short peptide with hydrolysis cleavage activity, an endogenous metabolite .
|
-
-
- HY-P1714
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FE 203799
|
GLP Receptor
|
Metabolic Disease
|
Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum .
|
-
-
- HY-P10704
-
|
Integrin
|
Cancer
|
C16Y is a short peptide and an inhibitor of integrins αvβ3 and α5β1. C16Y acts on the cell membrane and exerts its anticancer activity by inhibiting angiogenesis .
|
-
-
- HY-106428
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ITF1697
|
P-selectin
|
Cardiovascular Disease
Inflammation/Immunology
|
Icrocaptide (ITF1697) is a stable Lys-Pro-containing peptide that inhibits the intracellular Ca 2+-dependent fusion of Weibel-Palade bodies with the plasma membrane. Icrocaptide exerts its activity at the early stages of endothelial activation and inhibits P-selectin and von Willebrand factor secretion. Icrocaptide can be used for the study of a variety of microvascular disorders .
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-
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- HY-161394
-
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Others
|
Cancer
|
SPRT is a short peptide of RB transcriptional corepressor 1 (RB), serving as a fragment of RB-CO-PEG5-C2-CO-VH032 (HY-161393) for the synthesis of PROTAC .
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-
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- HY-P1714A
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FE 203799 TFA
|
GLP Receptor
|
Metabolic Disease
|
Apraglutide TFA (FE 203799 TFA), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum .
|
-
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- HY-172714A
-
|
Liposome
|
Infection
|
DSPE-PEG3400-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
|
-
-
- HY-172714
-
|
Liposome
|
Infection
|
DSPE-PEG2000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
|
-
-
- HY-172713
-
|
Liposome
|
Infection
|
DSPE-PEG1000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
|
-
-
- HY-172715
-
|
Liposome
|
Infection
|
DSPE-PEG5000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
|
-
-
- HY-14369
-
-
-
- HY-14789
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-
-
- HY-P1907
-
|
HPV
|
Cancer
|
Human Papillomavirus (HPV) E7 protein (49-57) is the H-2 d-restricted human papillomavirus (HPV) E749-57 epitope (short peptide spanning the 49th to 57th amino acid residues in the E7 protein) .
|
-
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- HY-P10251
-
|
HIV
|
Infection
|
HIV gp120 (318-327) is a short sequence of the HIV-1 strain IIIB envelope peptide (rgpgrafvti) that corresponds to the conserved C-terminal region of the glycoprotein. HIV gp120 (318-327) is part of the HIV vaccine V3 peptide epitope, also known as the I10 peptide. However, HIV gp120 (318-327) lacks the A2 anchor residues recognized by epitope-specific CTLs but has structural features that confer promiscuous A2 binding .
|
-
-
- HY-N7122
-
|
Endogenous Metabolite
|
Inflammation/Immunology
Cancer
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Thymopentin is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs) .
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-
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- HY-N7122A
-
|
Endogenous Metabolite
|
Inflammation/Immunology
Cancer
|
Thymopentin acetate is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin acetate is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin acetate enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs) .
|
-
-
- HY-P3320
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PC 3
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Biochemical Assay Reagents
|
Others
|
Phytochelatin 3 (PC 3) is the small metal chelating peptide that can be used for chelating heavy metals. Phytochelatin 3 is a short metal detoxification peptide made from the sulfur-rich molecule glutathione. Phytochelatin 3 can be found in different sources including plant, fungal, algal, and bacterial species, as a detoxification mechanism in response to heavy metal exposure. Phytochelatin 3 plays an important metabolic role in plants .
|
-
-
- HY-P10953
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PSP 29-mer, anti-inflammatory peptide
|
ERK
STAT
|
Inflammation/Immunology
|
Fulipiftide is a short peptide derived from pigment epithelium-derived factor (PEDF). Fulipiftide induces the expansion of nuclear stem cell factor +TSPC by activating ERK2 and STAT3 signaling pathways. Fulipiftide has anti-inflammatory activity and can be used in the study of acute tendon injury .
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-
-
- HY-E70528
-
|
Biochemical Assay Reagents
|
Others
|
PreScission Protease is a recombinant protease that combines human rhinovirus (HRV) type 14 3C protease and a GST-tag. PreScission Protease can specifically recognize the short peptide Leu-Glu-Val-Leu-Phe-Gln-Gly-Pro at 4°C and cleave between Gln and Gly amino acids .
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-
-
- HY-108717B
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Protease K (NGS grade)
|
Ser/Thr Protease
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Others
|
Proteinase K (Protease K) (NGS grade) (EC 3.4.21.64) is a serine protease with high enzyme activity and broad substrate specificity. Proteinase K can preferentially decompose ester bonds and peptide bonds adjacent to the C-terminus of hydrophobic amino acids, sulfur-containing amino acids, and aromatic amino acids, and is often used to degrade proteins to produce short peptides. This product is NGS grade, no Nickase residue, and nucleic acid residue ≤5pg/mg .
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-
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- HY-14789R
-
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GnRH Receptor
Nuclear Factor of activated T Cells (NFAT)
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Endocrinology
Cancer
|
(R)-Elagolix (Standard) is the analytical standard of (R)-Elagolix. This product is intended for research and analytical applications. Elagolix is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (KD = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .
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-
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- HY-16707
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Z-Ile-Glu-Pro-Phe-Ome
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Proteasome
|
Inflammation/Immunology
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CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a selective short peptide human cardiac chymase inhibitor. CH-5450 inhibits the action of rat MAB elastase 2 on substrate Ang I with an IC50 value of 49 µM and N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide with an IC50 value of 4.8 µM .
|
-
-
- HY-135773
-
|
Prostaglandin Receptor
PDK-1
|
Cardiovascular Disease
Inflammation/Immunology
|
CRTh2 antagonist 3 is a potent chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTh2) antagonist . CRTh2 antagonist 3 enhances the activity of PDK1 toward a short peptide substrate, with an EC50 of 2 μM and a Kd of 8.4 μM. CRTh2 antagonist 3 has the potential for cardiovascular inflammation .
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-
-
- HY-P1629
-
|
Bacterial
Fungal
Antibiotic
|
Infection
|
Temporin A is a short alpha-helical antimicrobial peptide isolated from the skin of the frog Rana temporaria. Temporin A is effective against a broad spectrum of Gram-positive bacteria. Temporin A interacts directly with the cell membrane of the microorganism and it is non-toxic to erythrocytes at concentrations that are antimicrobial. Temporin A also has antifungal activities (against yeast-like Candida albicans) .
|
-
-
- HY-W751574
-
-
-
- HY-127090
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MDP
|
p38 MAPK
NOD-like Receptor (NLR)
|
Inflammation/Immunology
Cancer
|
Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide is an inducer of bone formation through induction of Runx2. Muramyl dipeptide directly enhances osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is a NLRP1 agonist .
|
-
-
- HY-112295
-
|
Biochemical Assay Reagents
|
Infection
|
AzKTB is a capture reagent which bears a short trypsin-cleavable peptide sequence between the azide module and the TAMRA/PEG-biotin labels. AzKTB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-155992
-
|
Sigma Receptor
|
Neurological Disease
|
WLB-89462 (Compound 20c) is a selective σ2 receptor ligand (Ki: 13 nM). WLB-89462 has neuroprotective activity. WLB-89462 improves short-term memory impairment induced by Aβ peptide in rats. WLB-89462 has good ADMET profile (good solubility, no CYP inhibition, good metabolic stability, high permeability, brain penetration, and high oral exposure in rodents) .
|
-
- HY-P11012
-
|
SARS-CoV
|
Infection
|
EK1 is a peptide-based fusion inhibitor of coronaviruses (CoVs) with broad spectrum inhibition to a number of CoV species. EK1 shows substantially improved pan-CoV fusion inhibitory activity. EK1 potently inhibits SARS-CoV-2. EK1 can form a stable six-helix bundle (6HB) structure with both short α-hCoV and long β-hCoV N-terminal heptad repeats .
|
-
- HY-P5520
-
|
Bombesin Receptor
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-172714A
-
|
Drug Delivery
|
DSPE-PEG3400-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
|
-
- HY-172714
-
|
Drug Delivery
|
DSPE-PEG2000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
|
-
- HY-172713
-
|
Drug Delivery
|
DSPE-PEG1000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
|
-
- HY-172715
-
|
Drug Delivery
|
DSPE-PEG5000-MPG is a PEG compound which composed of DSPE and a peptide vector (MPG). MPG is derived from both the nuclear localisation sequence (NLS) of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41. MPG could deliver short oligonucleotides into cells efficiently and independently of the endosomal pathway .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P1563
-
-
- HY-P3526
-
-
- HY-P2665
-
|
Peptides
|
Others
|
Lymphocyte activating pentapeptide is a short peptide sequence found in the Fc region of human IgG1 that has the ability to activate lymphocytes. Lymphocyte activating pentapeptide can be used to study the activation mechanisms of B cells and T cells, and their role in immune responses .
|
-
- HY-P1965
-
|
Peptides
|
Cancer
|
Ac-IEVDIDV TFA is a short peptide sequence with Ac at the end.
|
-
- HY-P1963
-
|
Peptides
|
Cancer
|
Ac-IEVDIDVEH TFA is a short peptide sequence with Ac at the end.
|
-
- HY-P1964
-
|
Peptides
|
Cancer
|
Ac-IEVDIDVE TFA is a short peptide sequence with Ac at the end.
|
-
- HY-P1966
-
|
Peptides
|
Cancer
|
Ac-IEVDID TFA is a short peptide sequence with Ac at the end.
|
-
- HY-P1967
-
|
Peptides
|
Cancer
|
Ac-VDID TFA is a short peptide sequence with Ac at the end.
|
-
- HY-P1512
-
|
SOD
|
Cancer
|
Antioxidant peptide A is a short peptide, which contains alternative aromatic or sulfur-containing amino acid. The side chains of Antioxidant peptide A are believed to contribute to strong radical scavenging activities of peptides in the cancer cell.
|
-
- HY-P3326
-
|
Bacterial
|
Infection
|
Targeting the bacterial sliding clamp peptide 46 is a short peptide targeting the bacterial sliding clamp(SC), inhibiting SC-dependent DNA synthesis.
|
-
- HY-P2193
-
|
Peptides
|
Infection
|
TAT-amide is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells .
|
-
- HY-P1512A
-
|
Peptides
|
Cancer
|
Antioxidant peptide A TFA is a short peptide, which contains alternative aromatic or sulfur-containing amino acid. The side chains of Antioxidant peptide A are believed to contribute to strong radical scavenging activities of peptides in the cancer cell .
|
-
- HY-P2193A
-
|
Peptides
|
Infection
|
TAT-amide TFA is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells .
|
-
- HY-P3599
-
|
Peptides
|
Others
|
P-T-P-S-NH2 is a short-chain peptide with an N-terminal proline .
|
-
- HY-103303
-
|
CGRP Receptor
|
Metabolic Disease
|
CRSP-1 is short for calcitonin receptor-stimulating peptide-1. CRSP-1 inhibits osteoclast formation by inhibiting the formation and activity of multinucleated osteoclast .
|
-
- HY-P1593
-
-
- HY-P1734
-
|
PKC
|
Neurological Disease
|
Ac-MBP 1-11, a short peptide sequence, is the major encephalitogenic epitope in myelin basic protein (MBP) .
|
-
- HY-134578
-
|
Drug Intermediate
|
Others
|
H-Arg-Ser-Arg-OH is a short peptide. H-Arg-Ser-Arg-OH is a motif of di-leucine and RSRR, it can be used to design larger peptides and compound .
|
-
- HY-P1593A
-
-
- HY-P10709
-
|
Biochemical Assay Reagents
|
Cardiovascular Disease
Cancer
|
CREKA peptide is a short peptide sequence, belonging to self-assembling peptides (SAPs), which can self-assemble into functional nanostructures, typically nanofibers, under physiological conditions. CREKA peptide can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity .
|
-
- HY-P10709A
-
|
Biochemical Assay Reagents
|
Cardiovascular Disease
Cancer
|
CREKA peptide acetate is a short peptide sequence, belonging to self-assembling peptides (SAPs), which can self-assemble into functional nanostructures, typically nanofibers, under physiological conditions. CREKA peptide acetate can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity .
|
-
- HY-P3321
-
PC 4
|
Peptides
|
Others
|
Phytochelatin 4 (PC 4) is a short Cys-rich peptide with repeating γ-Glu-Cys motifs found in plants .
|
-
- HY-P3321A
-
-
- HY-P2299
-
|
HPV
|
Cancer
|
Protein E7(43-62) is an E7-derived peptide with anti-tumor effects (short peptide spanning the 43th to 62th amino acid residues in the E7 protein) .
|
-
- HY-P10739
-
|
MMP
|
Inflammation/Immunology
|
WYRGRL, a collagen II-targeting peptide, can bind to collagen II α1. WYRGRL is a short cartilage-targeting peptide sequence. WYRGRL leads to about 72-fold increase of cartilage-targeting efficiency for the peptide-functionalized nanoplatform in vivo .
|
-
- HY-P2299A
-
|
HPV
|
Cancer
|
Protein E7(43-62) TFA is an E7-derived peptide with anti-tumor effects (short peptide spanning the 43th to 62th amino acid residues in the E7 protein) .
|
-
- HY-P3302
-
|
Biochemical Assay Reagents
|
Others
|
Sialylglycopeptide is a complex N-glycan, bearing a short peptide fragment. Sialylglycopeptide, as a starting material for the semi-synthesis of N-glycans, can be used for various researches .
|
-
- HY-P10705
-
|
Biochemical Assay Reagents
|
Cancer
|
KGFRWR is a short peptide sequence, belonging to self-assembling peptides (SAPs), which can self-assemble into functional nanostructures, typically nanofibers, under physiological conditions. KGFRWR can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity .
|
-
- HY-P10541
-
|
HSP
|
Others
|
HSP70/DnaK substrate peptide is a short peptide that the HSP70/DnaK molecular chaperone can bind and act on. HSP70/DnaK substrate peptide can be used to study the mechanism of action of HSP70/DnaK in molecular chaperone function .
|
-
- HY-P3291
-
ZP7570
|
GCGR
|
Metabolic Disease
|
Dapiglutide (ZP7570) is a long-acting glucagon-like peptide-1 receptor 1R (GLP-1R)/Glucagon-like peptide-2 receptor (GLP-2R) dual agonist. Dapiglutide alleviates intestinal dysfunction in a mouse short bowel model and has anti-obesity effects .
|
-
- HY-P3869
-
[D-Arg2]Dermorphin-(1-4) amide
|
Peptides
|
Neurological Disease
|
Lumekefamide is a N-terminal shorter peptide amide of [D-Arg2]dermorphin with the hypothermic effect. Lumekefamide shows analgesic activity and degradation in soluble mouse liver and brain extracts .
|
-
- HY-P2512
-
|
Peptides
|
Others
|
Phytochelatin 2, a short phytochelatin, is a key plant peptide binding heavy metals. Phytochelatins are a diverse set of plant compounds that chelate metals, protect against metal toxicity and function in metal homeostasis .
|
-
- HY-103276
-
-
- HY-P1714
-
FE 203799
|
GLP Receptor
|
Metabolic Disease
|
Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum .
|
-
- HY-P10704
-
|
Integrin
|
Cancer
|
C16Y is a short peptide and an inhibitor of integrins αvβ3 and α5β1. C16Y acts on the cell membrane and exerts its anticancer activity by inhibiting angiogenesis .
|
-
- HY-106428
-
ITF1697
|
P-selectin
|
Cardiovascular Disease
Inflammation/Immunology
|
Icrocaptide (ITF1697) is a stable Lys-Pro-containing peptide that inhibits the intracellular Ca 2+-dependent fusion of Weibel-Palade bodies with the plasma membrane. Icrocaptide exerts its activity at the early stages of endothelial activation and inhibits P-selectin and von Willebrand factor secretion. Icrocaptide can be used for the study of a variety of microvascular disorders .
|
-
- HY-P1714A
-
FE 203799 TFA
|
GLP Receptor
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Metabolic Disease
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Apraglutide TFA (FE 203799 TFA), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum .
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- HY-P4116
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pHLIP
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Peptides
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Metabolic Disease
Cancer
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pH-Low Insertion Peptide (pHLIP) is a short, pH-responsive peptide capable of inserting across a cell membrane to form a transmembrane helix at acidic pH. pH-Low Insertion Peptide targets the acidic tumor microenvironment for tumors at early and metastatic stages with high specificity, used as a specific ligand. pH-Low Insertion Peptide successfully modify polylysine polymers to have the pH-responsive capability. pH-Low Insertion Peptide-based targeting of cancer presents an opportunity to monitor metabolic changes, and to selectively deliver imaging and therapeutic agents to tumors .
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- HY-P10496
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Peptides
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Cancer
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MAGE-A1-derived peptide is a short peptide sequence derived from MAGE-A1 protein. As a tumor-specific antigen, MAGE-A1-derived peptide can be recognized and activated by cytotoxic T lymphocytes (CTLs), thereby generating an immune response to tumor cells expressing MAGE-A1. This immune response can lead to the lysis and death of tumor cells. MAGE-A1-derived peptide can be used in the study of tumor immunity .
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- HY-P10496A
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Peptides
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Cancer
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MAGE-A1-derived peptide acetate is a short peptide sequence derived from MAGE-A1 protein. As a tumor-specific antigen, MAGE-A1-derived peptide acetate can be recognized and activated by cytotoxic T lymphocytes (CTLs), thereby generating an immune response to tumor cells expressing MAGE-A1. This immune response can lead to the lysis and death of tumor cells. MAGE-A1-derived peptide acetate can be used in the study of tumor immunity .
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- HY-P1907
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HPV
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Cancer
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Human Papillomavirus (HPV) E7 protein (49-57) is the H-2 d-restricted human papillomavirus (HPV) E749-57 epitope (short peptide spanning the 49th to 57th amino acid residues in the E7 protein) .
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- HY-P10989
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Peptides
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Cancer
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NG2 binding peptide is a short peptide that specifically recognizes NG2 proteoglycan and can be obtained by phage screening technology. NG2 binding peptide interacts with NG2 binding sites to achieve precise targeting of tumor angiogenesis in vitro and in vivo. NG2 binding peptide exhibits significant homing ability in wild-type tumor-bearing mice, but has no localization effect in NG2 knockout mice. Due to the tissue specificity of NG2 expression, NG2 binding peptide can be used in scenarios such as tumor targeted therapy, drug delivery, and molecular imaging diagnosis .
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- HY-P4116A
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pHLIP TFA
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Peptides
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Metabolic Disease
Cancer
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pH-Low Insertion Peptide TFA (pHLIP TFA) is a short, pH-responsive peptide capable of inserting across a cell membrane to form a transmembrane helix at acidic pH. pH-Low Insertion Peptide TFA targets the acidic tumor microenvironment for tumors at early and metastatic stages with high specificity, used as a specific ligand. pH-Low Insertion Peptide TFA successfully modifys polylysine polymers to have the pH-responsive capability. pH-Low Insertion Peptide TFA -based targeting of cancer presents an opportunity to monitor metabolic changes and to selectively deliver imaging and therapeutic agents to tumors .
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- HY-P10251
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HIV
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Infection
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HIV gp120 (318-327) is a short sequence of the HIV-1 strain IIIB envelope peptide (rgpgrafvti) that corresponds to the conserved C-terminal region of the glycoprotein. HIV gp120 (318-327) is part of the HIV vaccine V3 peptide epitope, also known as the I10 peptide. However, HIV gp120 (318-327) lacks the A2 anchor residues recognized by epitope-specific CTLs but has structural features that confer promiscuous A2 binding .
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- HY-P4793
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Peptides
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Metabolic Disease
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Acetyl-Heme-Binding Protein 1 (1-21) (human) is a short peptide. It consists of the first 21 amino acids of the hemopexin Acetyl-Heme-Binding Protein 1. Acetyl-Heme-Binding Protein 1 can bind to heme and play a role in heme metabolism and hemoglobin release .
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- HY-N7122
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Endogenous Metabolite
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Inflammation/Immunology
Cancer
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Thymopentin is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs) .
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- HY-N7122A
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Endogenous Metabolite
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Inflammation/Immunology
Cancer
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Thymopentin acetate is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin acetate is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin acetate enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs) .
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- HY-P3320
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PC 3
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Biochemical Assay Reagents
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Others
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Phytochelatin 3 (PC 3) is the small metal chelating peptide that can be used for chelating heavy metals. Phytochelatin 3 is a short metal detoxification peptide made from the sulfur-rich molecule glutathione. Phytochelatin 3 can be found in different sources including plant, fungal, algal, and bacterial species, as a detoxification mechanism in response to heavy metal exposure. Phytochelatin 3 plays an important metabolic role in plants .
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- HY-P10953
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PSP 29-mer, anti-inflammatory peptide
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ERK
STAT
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Inflammation/Immunology
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Fulipiftide is a short peptide derived from pigment epithelium-derived factor (PEDF). Fulipiftide induces the expansion of nuclear stem cell factor +TSPC by activating ERK2 and STAT3 signaling pathways. Fulipiftide has anti-inflammatory activity and can be used in the study of acute tendon injury .
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- HY-16707
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Z-Ile-Glu-Pro-Phe-Ome
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Proteasome
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Inflammation/Immunology
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CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a selective short peptide human cardiac chymase inhibitor. CH-5450 inhibits the action of rat MAB elastase 2 on substrate Ang I with an IC50 value of 49 µM and N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide with an IC50 value of 4.8 µM .
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- HY-P1629
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Bacterial
Fungal
Antibiotic
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Infection
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Temporin A is a short alpha-helical antimicrobial peptide isolated from the skin of the frog Rana temporaria. Temporin A is effective against a broad spectrum of Gram-positive bacteria. Temporin A interacts directly with the cell membrane of the microorganism and it is non-toxic to erythrocytes at concentrations that are antimicrobial. Temporin A also has antifungal activities (against yeast-like Candida albicans) .
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- HY-P11012
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SARS-CoV
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Infection
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EK1 is a peptide-based fusion inhibitor of coronaviruses (CoVs) with broad spectrum inhibition to a number of CoV species. EK1 shows substantially improved pan-CoV fusion inhibitory activity. EK1 potently inhibits SARS-CoV-2. EK1 can form a stable six-helix bundle (6HB) structure with both short α-hCoV and long β-hCoV N-terminal heptad repeats .
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- HY-P5520
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Bombesin Receptor
Radionuclide-Drug Conjugates (RDCs)
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Cancer
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GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-W751574
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Elagolix-d6 (sodium) (NBI-56418-d6 (sodium)) is deuterium labeled Elagolix sodium. Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (KD = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .
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Product Name |
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Classification |
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- HY-112295
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Azide
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AzKTB is a capture reagent which bears a short trypsin-cleavable peptide sequence between the azide module and the TAMRA/PEG-biotin labels. AzKTB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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