2. Anti-infection
  3. HPV
  4. Protein E7(43-62) TFA

Protein E7(43-62) TFA is an E7-derived peptide with anti-tumor effects (short peptide spanning the 43th to 62th amino acid residues in the E7 protein).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Protein E7(43-62) TFA Chemical Structure

Protein E7(43-62) TFA Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of Protein E7(43-62) TFA:

Protein E7(43-62) TFA Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

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Description

Protein E7(43-62) TFA is an E7-derived peptide with anti-tumor effects (short peptide spanning the 43th to 62th amino acid residues in the E7 protein)[1].

In Vivo

Using an E7-derived peptide Protein E7(43-62), 50% of mice (C57BL/6 mice bearing human papilloma virus (HPV) E6/7 TC-1 tumors) are tumor free 60 days after treatment with Protein E7(43-62)-polymeric nanoparticle (PC7A NP)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

2384.54

Formula

C97H145N28F3O33S3
Appearance

Solid

Color

White to off-white

Sequence Shortening

GQAEPDRAHYNIVTFCCKCD
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (10.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 10 mg/mL (4.19 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4194 mL 2.0968 mL 4.1937 mL
5 mM 0.0839 mL 0.4194 mL 0.8387 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.85%

SDS (252 KB)

COA (242 KB) RP-HPLC (250 KB) MS (109 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 0.4194 mL 2.0968 mL 4.1937 mL 10.4842 mL
DMSO 5 mM 0.0839 mL 0.4194 mL 0.8387 mL 2.0968 mL
10 mM 0.0419 mL 0.2097 mL 0.4194 mL 1.0484 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Protein E7(43-62) TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Protein E7(43-62)HPVHuman papillomavirusPC7Ananoparticleanti-tumorpeptidimmunotherapySTINGnanovaccineInhibitorinhibitorinhibit

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