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Results for "

pituitary

" in MedChemExpress (MCE) Product Catalog:

By Targets:	PACAP Receptor (5) Adenylate Cyclase (2) Adrenergic Receptor (3) Androgen Receptor (3) Antibiotic (3) Apoptosis (10) Bacterial (2) Biochemical Assay Reagents (3) Bombesin Receptor (1) Calcium Channel (1) CaMK (1) Cholinesterase (ChE) (1) CRFR (4) DNA/RNA Synthesis (2) Dopamine Receptor (1) Endogenous Metabolite (16) Epigenetic Reader Domain (2) ERK (2) Estrogen Receptor/ERR (2) Flavivirus (2) GCGR (1) GHSR (7) Glucocorticoid Receptor (2) GnRH Receptor (19) HSV (2) Isotope-Labeled Compounds (4) MCHR1 (GPR24) (2) Melanocortin Receptor (2) mGluR (1) Mineralocorticoid Receptor (1) Necroptosis (1) Neurokinin Receptor (1) Neuropeptide B/W Receptor (2) Neuropeptide Y Receptor (1) Opioid Receptor (2) Orthopoxvirus (2) p38 MAPK (1) PGC-1α (2) PKC (1) Potassium Channel (1) Progesterone Receptor (1) Proteasome (1) Reactive Oxygen Species (ROS) (1) Reference Standards (4) Somatostatin Receptor (4) Thyroid Hormone Receptor (2) TNF Receptor (2) Toll-like Receptor (TLR) (1) TSH Receptor (2) Vasopressin Receptor (7)
By Research Areas:	Cancer (18) Cardiovascular Disease (12) Endocrinology (57) Infection (4) Inflammation/Immunology (12) Metabolic Disease (16) Neurological Disease (37)

By Targets:

PACAP Receptor (5)

Adenylate Cyclase (2)

Adrenergic Receptor (3)

Androgen Receptor (3)

Antibiotic (3)

Apoptosis (10)

Bacterial (2)

Biochemical Assay Reagents (3)

Bombesin Receptor (1)

Calcium Channel (1)

CaMK (1)

Cholinesterase (ChE) (1)

CRFR (4)

DNA/RNA Synthesis (2)

Dopamine Receptor (1)

Endogenous Metabolite (16)

Epigenetic Reader Domain (2)

ERK (2)

Estrogen Receptor/ERR (2)

Flavivirus (2)

GCGR (1)

GHSR (7)

Glucocorticoid Receptor (2)

GnRH Receptor (19)

HSV (2)

Isotope-Labeled Compounds (4)

MCHR1 (GPR24) (2)

Melanocortin Receptor (2)

mGluR (1)

Mineralocorticoid Receptor (1)

Necroptosis (1)

Neurokinin Receptor (1)

Neuropeptide B/W Receptor (2)

Neuropeptide Y Receptor (1)

Opioid Receptor (2)

Orthopoxvirus (2)

p38 MAPK (1)

PGC-1α (2)

PKC (1)

Potassium Channel (1)

Progesterone Receptor (1)

Proteasome (1)

Reactive Oxygen Species (ROS) (1)

Reference Standards (4)

Somatostatin Receptor (4)

Thyroid Hormone Receptor (2)

TNF Receptor (2)

Toll-like Receptor (TLR) (1)

TSH Receptor (2)

Vasopressin Receptor (7)

By Research Areas:

Cancer (18)

Cardiovascular Disease (12)

Endocrinology (57)

Infection (4)

Inflammation/Immunology (12)

Metabolic Disease (16)

Neurological Disease (37)

115

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: PACAP Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P3117

PACAP (6-27) (human, ovine, rat) pituitary adenylate cyclase-activating peptide (6-27)	Adenylate Cyclase	Neurological Disease
PACAP (6-27) (human, ovine, rat) is a PACAP receptor antagonist that blocks the canine adrenal catecholamine response to exogenous vasoactive intestinal peptide (VIP). PACAP (6-27) (human, ovine, rat) has the potential to study cardiovascular and neurological diseases .

HY-P0221

PACAP (1-38), human, ovine, rat 5 Publications Verification pituitary Adenylate Cyclase Activating Polypeptide 38	PACAP Receptor	Neurological Disease
PACAP (1-38), human, ovine, rat is a neuropeptide with 38 amino acid residues. PACAP (1-38) binds to PACAP type I receptor, PACAP type II receptor VIP₁, and PACAP type II receptor VIP₂ with IC₅₀s of 4 nM, 2 nM, and 1 nM, respectively.

HY-B1811

Vasopressin 5 Publications Verification	Endogenous Metabolite	Neurological Disease
Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-P2293

Luteinizing hormone (human)	Endogenous Metabolite	Endocrinology
Luteinizing hormone (human), a heterodimeric glycoprotein hormone produced by the pituitary gland (LH), plays key roles in human reproduction .

HY-P0221A

PACAP (1-38), human, ovine, rat TFA pituitary Adenylate Cyclase Activating Polypeptide 38 TFA	PACAP Receptor	Neurological Disease
PACAP (1-38), human, ovine, rat TFA is a neuropeptide with 38 amino acid residues. PACAP (1-38) binds to PACAP type I receptor, PACAP type II receptor VIP₁, and PACAP type II receptor VIP₂ with IC₅₀s of 4 nM, 2 nM, and 1 nM, respectively.

HY-NP199

*Bovine pituitary* extract**	Biochemical Assay Reagents	Others
Bovine pituitary extract is a bovine pituitary extract that can be used as a mitogenic supplement in serum-free growth medium .

HY-B1811R

Vasopressin (Standard)	Endogenous Metabolite	Neurological Disease
Vasopressin (Standard) is the analytical standard of Vasopressin. This product is intended for research and analytical applications. Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-P2357

MI-1544	GnRH Receptor	Metabolic Disease
MI-1544 is a powerful GnRH antagonist. MI-1544 induces inhibitory effects on the pituitary LH release and on gonads. MI-1544 can be used for the research of antifertility effect .

HY-117965

Miricorilant CORT 118335	Glucocorticoid Receptor Mineralocorticoid Receptor	Endocrinology
Miricorilant (CORT 118335) is a dual selective glucocorticoid (GR) modulator/mineralocorticoid (MR) antagonist. Miricorilant can be used for the research of hypothalamic-pituitary-adrenal (HPA) axis related disorders .

HY-172299

Delmadinone acetate	Melanocortin Receptor	Endocrinology
Delmadinone acetate is an orally active compound that can control estrus and ovulation in female and male pets. Delmadinone acetate causes adrenal suppression from inhibition of release of ACTH from the pituitary gland .

HY-E70001

Recombinant Human Luteinizing Hormone	Others	Endocrinology
Recombinant Human Luteinizing Hormone is a recombinant form of Luteinizing hormone (human) (HY-P2293). Luteinizing hormone (human), a heterodimeric glycoprotein hormone produced by the pituitary gland (LH), plays key roles in human reproduction .

HY-N10520

Pectic acid Methyl protopectin; Polygalacturonic acid	Apoptosis Necroptosis Endogenous Metabolite	Inflammation/Immunology Cancer
Pectic acid (Methyl protopectin), a polygalacturonic acid, induces cell apoptosis and necrosis in pituitary tumor cells. Pectic acid can be used in the research of cancers and autoimmune disease .

HY-P4012

[Asu1,6-Arg8]Vasopressin	Vasopressin Receptor	Endocrinology
[Asu1,6-Arg8]Vasopressin is an vasopressin agonist which potentiates cyclic AMP accumulation and ACTH release induced by corticotropin-releasing factor (CRF) in rat anterior pituitary cells in culture .

HY-P3567

(p-Iodo-Phe7)-ACTH (4-10)	Melanocortin Receptor	Neurological Disease
(p-Iodo-Phe7)-ACTH (4-10) is a adrenocorticotrophic hormone (ACTH) derivative, which is produced and secreted by the anterior pituitary gland. (p-Iodo-Phe7)-ACTH (4-10) serves as a melanocortin (MC) receptor antagonist and inhibits α-melanocyte-stimulating hormone (α-MSH)-induced excessive grooming behavior in rats .

HY-107916

Thyrotropin 1 Publications Verification TSH; Pretiron	TSH Receptor PKC Apoptosis	Metabolic Disease Inflammation/Immunology Endocrinology Cancer
Thyrotropin (TSH, Pretiron) is a thyroid-stimulating hormone produced by thyrotrope cells in the anterior pituitary gland. Thyrotropin regulates the endocrine function of the thyroid. Thyrotropin induces transcriptional regulation of TH-gatekeeper genes in tanycytes through the Tshr/Gαq/PKC pathway. Thyrotropin prevents Apoptosis. Thyrotropin has an association of low levels with increased bone remodeling, reduced bone mass and a high fracture risk in mice. Thyrotropin is promising for research of skeletal remodeling, hyperthyroidism .

HY-P2110

RS-18286	GnRH Receptor	Endocrinology
RS-18286 is a potent luteinizing-hormone (LH)-releasing hormone (LHRH) antagonist. RS-18286 blocks the pituitary LHRH receptor and suppresses pituitary luteinizing-hormone (LH) secretion and reduce serum concentrations of gonadal steroids .

HY-P0086

Corticotropin-releasing factor (human) 3 Publications Verification Human CRF; Human corticotropin-releasing factor	CRFR	Neurological Disease
Corticotropin-releasing factor human (Human CRF) stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.

HY-NP197

Human follicle stimulating hormone FSH	Biochemical Assay Reagents	Others
Human follicle stimulating hormone (FSH) belongs to the glycoprotein hormone family and is secreted by gonadotropin cells of the pituitary gland .

HY-P3219

N-Acetyloxytocin	Endogenous Metabolite	Endocrinology
N-Acetyloxytocin is isolated and characterized in the neurointermediate lobe of the rat pituitary (NIL) and their presence in several brain areas of the rat .

HY-P0246

Mastoparan	Endogenous Metabolite	Metabolic Disease
Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells.

HY-P1476

Adrenocorticotropic Hormone (ACTH) (18-39), human CLIP (human)	Endogenous Metabolite	Metabolic Disease
Adrenocorticotropic Hormone (ACTH) (18-39), human is a corticotropinlike intermediate lobe peptide, which is produced in the melanotrophs of the intermediate lobe of the pituitary.

HY-B1811S1

Vasopressin-d5	Isotope-Labeled Compounds	Others
Vasopressin-d5 is anIsotope-labeled compound of Vasopressin. Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of the corticotropin-releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-B1617

Zuclomiphene	Estrogen Receptor/ERR	Metabolic Disease
Zuclomiphene (compound 23) is a potent inhibitor of 17β-Estradiol (HY-B0141) and can inhibit the secretion of luteinizing hormone (LH) .

HY-15242

Capromorelin CP 424391	GHSR	Endocrinology
Capromorelin (CP 424391) is a pyrazolinone-piperidine dipeptide. Capromorelin is an orally active and potent growth hormone secretagogue (GHS) (hGHS-R1a K_i=7 nM, rat pituicyte EC₅₀=3 nM) .

HY-106373

Adrenocorticotropic hormone ACTH; Adrenocorticotrophic hormone	Androgen Receptor	Endocrinology
Adrenocorticotropic hormone (ACTH) is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone regulates cortisol and androgen production .

HY-P1476A

Adrenocorticotropic Hormone (ACTH) (18-39), human TFA CLIP (human) TFA	Endogenous Metabolite	Metabolic Disease
Adrenocorticotropic Hormone (ACTH) (18-39), human TFA is a corticotropinlike intermediate lobe peptide, which is is produced in the melanotrophs of the intermediate lobe of the pituitary .

HY-P3056

GHRF, ovine	GHSR	Endocrinology
GHRF, ovine is a growth hormone-releasing factor. GHRF is a specific mediator for the effects of hypoglycemia upon the release of pituitary growth hormone (GH) .

HY-107953

Chorionic gonadotrophin 2 Publications Verification hCG; Chorionic gonadotropic hormone	Endogenous Metabolite	Endocrinology Cancer
Chorionic gonadotrophin (hCG) is a gonadotropin that can be isolated from the anterior pituitary gland. Chorionic gonadotrophin has potential applications in ovarian and follicular development .

HY-106373A

Adrenocorticotropic hormone TFA ACTH TFA; Adrenocorticotrophic hormone TFA	Androgen Receptor	Metabolic Disease
Adrenocorticotropic hormone (ACTH) TFA is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone regulates cortisol and androgen production .

HY-125611

Fluorogestone acetate	GnRH Receptor	Endocrinology
Fluorogestone acetate is a progesterone compound. Fluorogestone acetate inhibits ovulation and synchronizes the estrous cycle in cattle by inhibiting the release of luteinizing hormone (LH) from the pituitary gland .

HY-111182

Estrone acetate Hogival; Oestrone-3-acetate; Puboestrene	Estrogen Receptor/ERR	Endocrinology
Estrone acetate (Hogival) is an estrogen derivative and an estrogen receptor (ER) activator. It promotes mammary gland development, stimulates pituitary prolactin secretion, and induces the proliferation and activation of lactotrophs (e.g., by reducing prolactin storage granule size while increasing rough endoplasmic reticulum and Golgi apparatus volume density). Estrone acetate holds potential for endocrine research, particularly in studying estrogen's effects on pituitary function, prolactin regulation, and mammary tumor models .

HY-P3964

TRH Precursor Peptide	Endogenous Metabolite	Endocrinology
TRH Precursor Peptide is a precursor peptide of thyrotropin-releasing hormone (TRH). TRH Precursor Peptide formation of TRH in rat brain and pituitary is zinc-dependent .

HY-107380A

PGlu-3-methyl-His-Pro-NH2 TFA A-42872 TFA	TSH Receptor	Endocrinology
PGlu-3-methyl-His-Pro-NH2 TFA (A-42872 TFA), the modified thyrotropin-releasing hormone (TRH) peptide, enhances binding to pituitary TRH receptors and increases stimulation of thyroid-stimulating hormone (TSH) release from the pituitary. The in vitro permeability of PGlu-3-methyl-His-Pro-NH2 TFA through rat skin is increased in the presence of enhancers Ethanol and Cineole .

HY-P0238

Gastrin-Releasing Peptide, human	Bombesin Receptor	Cancer
Gastrin-Releasing Peptide, human (GRP) belongs to the bombesin-like peptide family, and is not a classical hypothalamic-hypophyseal regulatory hormone since it plays only a perfunctory role in the mediation of pituitary hormone release.

HY-P1905

[Gln8]-C517 (LH-RH), chicken	GnRH Receptor	Endocrinology
[Gln8]-C517 (LH-RH), chicken is an avian hypothalamic peptide, which stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions.

HY-P0089

Human growth hormone-releasing factor Growth Hormone Releasing Factor human; Somatorelin (1-44) amide (human)	GHSR	Endocrinology
Human growth hormone-releasing factor (Growth Hormone Releasing Factor human) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary .

HY-P2446

ORG 30276 APTAA-LHRH	GnRH Receptor	Endocrinology
ORG 30276 (APTAA-LHRH) is a potent GnRH antagonist that effectively reduces serum LH and FSH levels in male rats. ORG 30276 significantly decreases unoccupied pituitary GnRH receptors, leading to suppressed gonadotropin secretion. ORG 30276 treatment results in a considerable reduction in mRNA levels of gonadotropin beta-subunits in the pituitary gland. ORG 30276's effects on gonadotropin dynamics can be selectively reversed by the replacement of specific sex steroids, with androgens being particularly effective for the FSH beta-subunit mRNA levels.

HY-P0089A

Human growth hormone-releasing factor TFA Growth Hormone Releasing Factor human TFA; Somatorelin (1-44) amide (human) (TFA)	GHSR	Endocrinology
Human growth hormone-releasing factor TFA (Growth Hormone Releasing Factor human TFA) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary .

HY-P3675

LH-RH (4-10)	GnRH Receptor	Endocrinology
LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes .

HY-B1811AS1

Vasopressin-d5 TFA	Isotope-Labeled Compounds	Neurological Disease
Vasopressin-d5 TFA is the TFA salt form of Vasopressin-d5 (HY-B1811S1). Vasopressin-d5 TFA is an isotope-labeled compound of Vasopressin (HY-B1811). Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of the corticotropin-releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-P3084

Human follicular gonadotropin releasing peptide hF-GRP	GnRH Receptor	Endocrinology
Human follicular gonadotropin releasing peptide (hF-GRP) is a hormone peptide. Human follicular gonadotropin releasing peptide can stimulate pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion in vitro .

HY-103560

(S)-HexylHIBO	mGluR	Neurological Disease
(S)-HexylHIBO is the S-enantiomer of HexylHIBO. HexylHIBO is a group I mGluR antagonist. HexylHIBO elevates the hypothalamus-pituitary-adrenal axis response to restraint in rats. HexylHIBO is promising for research of central nervous system-related diseases .

HY-107002A

Lergotrile mesylate	Dopamine Receptor	Neurological Disease Endocrinology
Lergotrile mesylate is a potent and orally active dopamine agonist and a prolactin secretion inhibitor. Lergotrile mesylate inhibits prolactin release from pituitaries by activating an adenohypophyseal dopamine receptor. Lergotrile mesylate has the potential for the research of Parkinson's disease .

HY-119332

3-Keto petromyzonol	Endogenous Metabolite	Endocrinology
3-Keto petromyzonol, a main component of Sea lamprey male sex pheromones, modulates both synthesis and release of gonadotropin releasing hormone (GnRH), and subsequently, hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey .

HY-NP198

Human prolactin	Biochemical Assay Reagents	Endocrinology
Human prolactin is a four-α-helix bundle protein hormone secreted by the anterior pituitary gland. The biological activities of Prolactin are mediated by its binding to the PRL receptor (PRLR) in a one-to-two complex and regulated by tertiary structural properties .

HY-138096

Z-LLF-CHO Z-Leu-Leu-Phe-CHO	Proteasome	Cancer
Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) is a potent inhibitor of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex (K_i = 460 nM). Z-LLF-CHO is also a NF-κB nuclear translocation inhibitor .

HY-P3674

LH-RH (7-10)	GnRH Receptor	Endocrinology
LH-RH (7-10) is a tetrapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (7-10) produced in macrophages, type I-like and type II pneumocytes .

HY-P4456

(Des-His6)-ACTH (1-24) (human, bovine, rat)	Adrenergic Receptor	Endocrinology
(Des-His6)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .

HY-P4413

(Des-Glu5)-ACTH (1-24) (human, bovine, rat)	Androgen Receptor	Endocrinology
(Des-Glu5)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .

HY-P1298

Sauvagine	CRFR	Cardiovascular Disease Neurological Disease Endocrinology
Sauvagine, a 40-amino-acid neuropeptide from the skin of the frog, is a mammalian CRF agonist. Sauvagine is effective at releasing ACTH from rat pituitary cells. Sauvagine possesses a number of pharmacological actions on diuresis, the cardiovascular system and endocrine glands .

Cat. No.	Product Name

HY-L188

Anti-Brain Cancer Compound Library

1,762 compounds

Although brain cancer only accounts for 2% of all tumors, it has a poor prognosis, high mortality and high recurrence rate. Brain cancer can be divided into primary brain cancer and secondary brain cancer. According to the location of the cancer, brain cancer can also be divided into: brain glioma, pituitary adenoma, schwannoma, craniopharyngioma, meningioma and so on. Glioma is the most common primary brain tumor, accounting for about 1/3 of all brain tumors. At present, brain cancer lacks precision targeted therapeutic drugs, and there is still a great clinical demand that has not been met. With the continuous development of high-throughput screening technology, it may be able to help develop effective anti-brain cancer drugs by screening compounds targeting PKC, PD-1, c-Met, PARP, etc targets.

MCE designs a unique collection of 1,762 small molecules with definite or potential anti-brain cancer activity, which is an important tool for studying the pathological mechanism of brain cancer and developing drugs for brain cancer.

Cat. No.	Product Name	Type

HY-D1056A3

Lipopolysaccharides, from E. coli O26:B6

LPS, from Escherichia coli (O26:B6)

Carbohydrates

Lipopolysaccharides, from E. coli (Escherichia coli) O26:B6 are lipopolysaccharide endotoxins and TLR-4 activators derived from E. coli, classified as S-type LPS, which can activate pathogen-associated molecular patterns (PAMP) of the immune system and induce cellular secretion of migrasomes. Lipopolysaccharides, from E. coli O26:B6 exhibit a typical three-part structure: O-antigen (O-antigen), core oligosaccharide (core oligosaccharide), and lipid A (Lipid A), and can be recognized by the core-specific monoclonal antibody MAb J8-4C10. Lipopolysaccharides, from E. coli O26:B6 can promote an increase in pro-inflammatory cytokines in plasma, thereby triggering hypothalamic-pituitary-adrenal (HPA) activation and leading to adrenal oxidative damage. The pathogenic effects of Lipopolysaccharides, from E. coli O26:B6 can be blocked by PD149163 (HY-123434) .
It is recommended to prepare a stock solution of ≥2 mg/mL and ensure that it is fully mixed and dissolved. Due to the adsorption characteristics of LPS, low adsorption centrifuge tubes should be used for aliquoting and storage.

HY-NP199

*Bovine pituitary* extract**	Microbial Culture
Bovine pituitary extract is a bovine pituitary extract that can be used as a mitogenic supplement in serum-free growth medium .

HY-NP197

Human follicle stimulating hormone FSH	Native Proteins
Human follicle stimulating hormone (FSH) belongs to the glycoprotein hormone family and is secreted by gonadotropin cells of the pituitary gland .

HY-NP198

Human prolactin	Native Proteins
Human prolactin is a four-α-helix bundle protein hormone secreted by the anterior pituitary gland. The biological activities of Prolactin are mediated by its binding to the PRL receptor (PRLR) in a one-to-two complex and regulated by tertiary structural properties .

Cat. No.	Product Name	Target	Research Area

HY-P991511

ALD1910	PACAP Receptor	Neurological Disease
ALD1910 is a humanized monoclonal antibody against PACAP38 and PACAP27. ALD1910 blocks PACAP signaling through the pituitary adenylate cyclase-activating peptide type I receptor (PAC1-R), vasoactive intestinal peptide receptor 1 (VPAC1-R), and VPAC2-R. ALD1910 recognizes a nonlinear epitope within PACAP and blocks its binding to the cell surface. ALD1910 can be used for the study of PACAP-mediated migraine .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1811

Vasopressin 5 Publications Verification	Structural Classification Neurological Disease Classification of Application Fields Cyclopeptides Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-P0246

Mastoparan	Structural Classification Natural Products Animals Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Endogenous Metabolite
Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells.

HY-107953

Chorionic gonadotrophin 2 Publications Verification hCG; Chorionic gonadotropic hormone	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology	Endogenous Metabolite
Chorionic gonadotrophin (hCG) is a gonadotropin that can be isolated from the anterior pituitary gland. Chorionic gonadotrophin has potential applications in ovarian and follicular development .

HY-N12634

Pregnant mare serum gonadotropin PMSG	Structural Classification Natural Products Animals Source classification	Endogenous Metabolite
Pregnant mare serum gonadotropin (PMSG) is a gonadotropin used to promote follicular development and ovulation in animals. PMSG exerts its regulatory effects by stimulating changes in blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus. PMSG is commonly used in livestock to improve reproductive efficiency and can also be utilized for research on estrous cycle regulation .

HY-Z0478

(-)-Limonene 1 Publications Verification (S)-(-)-Limonene	Cardiovascular Disease Structural Classification Other Monoterpenes Microorganisms Classification of Application Fields Terpenoids Source classification Rutaceae Plants Citrus Disease Research Fields	Bacterial Antibiotic CaMK
(-)-Limonene ((S)-(-)-Limonene) is orally active and can cause mild bronchoconstriction. (-)-Limonene alleviates cytosolic and mitochondrial oxidative stress by inhibiting the increase of calcium ions (Ca ²⁺) and Ca ²⁺/calmodulin-dependent protein kinase II (CaMKII). It also exerts anti-stress effects by inhibiting the activity of the hypothalamic-pituitary-adrenal (HPA) axis. Additionally, (-)-Limonene can be used as an antibacterial agent in aquaculture .

HY-N6733

Aphidicolin Maximum Cited Publications 9 Publications Verification	Structural Classification Microorganisms Classification of Application Fields Terpenoids Source classification Diterpenoids Inflammation/Immunology Disease Research Fields	DNA/RNA Synthesis HSV Apoptosis Antibiotic Orthopoxvirus
Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering DNA polymerase activity. Aphidicolin is an antibiotic produced by mold Cephalosporium aphidicola, inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line .

HY-B1811R

Vasopressin (Standard)	Structural Classification Cyclopeptides Source classification Endogenous metabolite	Endogenous Metabolite
Vasopressin (Standard) is the analytical standard of Vasopressin. This product is intended for research and analytical applications. Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-N10520

Pectic acid Methyl protopectin; Polygalacturonic acid	Structural Classification Natural Products Classification of Application Fields Source classification Rutaceae Plants Endogenous metabolite Citrus reticulata Blanco Human Gut Microbiota Metabolites Polysaccharides Microorganisms Inflammation/Immunology Disease Research Fields Saccharides Cancer	Apoptosis Necroptosis Endogenous Metabolite
Pectic acid (Methyl protopectin), a polygalacturonic acid, induces cell apoptosis and necrosis in pituitary tumor cells. Pectic acid can be used in the research of cancers and autoimmune disease .

HY-119332

3-Keto petromyzonol	Structural Classification Animals Classification of Application Fields Source classification Disease Research Fields Endocrinology Steroids	Endogenous Metabolite
3-Keto petromyzonol, a main component of Sea lamprey male sex pheromones, modulates both synthesis and release of gonadotropin releasing hormone (GnRH), and subsequently, hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey .

HY-N6733R

Aphidicolin (Standard)	Structural Classification Microorganisms Terpenoids Source classification Diterpenoids	Reference Standards DNA/RNA Synthesis HSV Apoptosis Antibiotic Orthopoxvirus
Aphidicolin (Standard) is the analytical standard of Aphidicolin. This product is intended for research and analytical applications. Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering DNA polymerase activity. Aphidicolin is an antibiotic produced by mold Cephalosporium aphidicola, inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line .

Species:	Human (9) Mouse (1)
Tag:	His (5) Tag Free (3) Avi (1) Fc (2)
Source:	HEK293 (6) E. coli Cell-free (1) CHO (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P7183

	GH/Somatotropin Protein, Human rHuGH; Somatotropin; GH-N; GH1; Growth hormone; Growth hormone 1; pituitary growth hormone	Human	E. coli
	GH Protein, Human is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration, which can be used for the treatment of growth disorders in children.

HY-P7360

	GH/Somatotropin Protein, Human (CHO) rHuGH; Somatotropin; GH-N; GH1; Growth hormone; Growth hormone 1; pituitary growth hormone	Human	CHO
	GH Protein, Human (CHO) is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration, which can be used for the treatment of growth disorders in children.

HY-P77120

	ADCYAP1R1 Protein, Human (HEK293, Fc) pituitary adenylate cyclase-activating polypeptide type I receptor; PACAP-R1; ADCYAP1R1	Human	HEK293
	The ADCYAP1R1 protein is a receptor for pituitary adenylate cyclase-activating polypeptide (PACAP) and recognizes PACAP-27 and PACAP-38. Through the G protein, this receptor activates adenylyl cyclase, initiating multiple downstream signaling pathways. ADCYAP1R1 Protein, Human (HEK293, Fc) is the recombinant human-derived ADCYAP1R1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77120A

	ADCYAP1R1 Protein, Human (HEK293, hFc) pituitary adenylate cyclase-activating polypeptide type I receptor; PACAP-R1; ADCYAP1R1	Human	HEK293
	The ADCYAP1R1 protein is a receptor for pituitary adenylate cyclase-activating polypeptide (PACAP) and recognizes PACAP-27 and PACAP-38. Through the G protein, this receptor activates adenylyl cyclase, initiating multiple downstream signaling pathways. ADCYAP1R1 Protein, Human (HEK293, hFc) is the recombinant human-derived ADCYAP1R1 protein, expressed by HEK293, with C-hFc labeled tag.

HY-P7869

	CG alpha Protein, Human (HEK293, His) rHuGlycoprotein hormones alpha chain/CGA, His; Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alph	Human	HEK293
	The CG alpha protein, a shared alpha chain in glycoprotein hormones (TSH, LH, FSH, CG), binds to receptors, initiating signaling pathways. Heterodimeric hormones involve CG alpha and a specific beta chain (TSHB, LHB, FSHB, CGB), imparting biological specificity. CG alpha Protein, Human (HEK293, His) is the recombinant human-derived CG alpha protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P7870

	CGA-CGB3 Heterodimer Protein, Human (HEK293, His) rHuGlycoprotein hormones alpha chain, C-Flag&Choriogonadotropin subunit beta 3, His; Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alph	Human	HEK293
	The CG alpha protein, a shared alpha chain in glycoprotein hormones (TSH, LH, FSH, CG), binds to receptors, initiating signaling pathways. Heterodimeric hormones involve CG alpha and a specific beta chain (TSHB, LHB, FSHB, CGB), imparting biological specificity. CGA-CGB3 Heterodimer Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived CGA-CGB3 Heterodimer protein, expressed by HEK293 , with C-6*His labeled tag. CGA-CGB3 Heterodimer Protein, Human (HEK293, His), has molecular weight of 22 & 30-35 kDa, respectively.

HY-P73085

	GH/Somatotropin Protein, Human (His) rHuGH; Somatotropin; GH-N; GH1; Growth hormone; Growth hormone 1; pituitary growth hormone	Human	E. coli
	Growth hormone (GH) plays a key role in growth control, stimulating the release of insulin-like growth factor 1 (IGF-1) from the liver and tissues to promote body growth. It regulates myoblast differentiation and proliferation and contributes significantly to overall organismal development. GH/Somatotropin Protein, Human (His) is the recombinant human-derived GH/Somatotropin protein, expressed by E. coli , with N-10*His labeled tag.

HY-P700610

	GH/Somatotropin Protein, Human (Biotinylated, HEK293, N-His, C-Avi) rHuGH; Somatotropin; GH-N; GH1; Growth hormone; Growth hormone 1; pituitary growth hormone	Human	HEK293
	Growth hormone (GH) plays a key role in growth control, stimulating the release of insulin-like growth factor 1 (IGF-1) from the liver and tissues to promote body growth. It regulates myoblast differentiation and proliferation and contributes significantly to overall organismal development. GH/Somatotropin Protein, Human (Biotinylated, HEK293, N-His, C-Avi) is the recombinant human-derived GH/Somatotropin protein, expressed by HEK293 , with C-Avi, N-10*His labeled tag.

HY-P702334

	IGSF1 Protein, Human (Cell-Free, His) Immunoglobulin superfamily member 1; Immunoglobulin-like domain-containing protein 1; Inhibin-binding protein; InhBP; pituitary gland-specific factor 2; p120	Human	E. coli Cell-free
	The IGSF1 protein acts as a coreceptor in inhibin signaling and is able to critically antagonize activin A signaling regardless of the presence of inhibin B. It plays a key role in the specific antagonism of inhibin B to activin-stimulated transcription and interacts with INHA. IGSF1 Protein, Human (Cell-Free, His) is the recombinant human-derived IGSF1 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.

HY-P703477

	mTSH Protein, Mouse (HEK293) Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain; Cga; Mus musculus; Mouse; FSH-alpha; Hormone	Mouse	HEK293
	mTSH Protein, Mouse (HEK293) is the recombinant mouse-derived mTSH, expressed by HEK293 , with tag Free labeled tag. ,

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Cat. No.	Product Name	Chemical Structure

HY-B1811AS1

Vasopressin-d5 TFA

Vasopressin-d5 TFA is the TFA salt form of Vasopressin-d5 (HY-B1811S1). Vasopressin-d5 TFA is an isotope-labeled compound of Vasopressin (HY-B1811). Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of the corticotropin-releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-13690S1

Mitotane-13C6

Mitotane- ¹³C₆ is the ¹³C labeled Mitotane . Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .

HY-B1811S1

Vasopressin-d5

Vasopressin-d5 is anIsotope-labeled compound of Vasopressin. Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of the corticotropin-releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .

HY-13690S2

Mitotane-d8

Mitotane-d₈ is the deuterium labeled Mitotane . Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .

HY-13690S3

Mitotane-13C12

Mitotane- ¹³C₁₂ (2,4′-DDD- ¹³C₁₂) is ¹³C labeled Mitotane. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .

HY-132184S

5,6-Epoxyeicosatrienoic acid-d11

5,6-Epoxyeicosatrienoic acid-d₁₁ (5,6-EET-d₁₁) is deuterium labeled 5,6-Epoxyeicosatrienoic acid. 5,6-Epoxyeicosatrienoic acid (5,6-EET; (±)5,6-EpETrE) is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5,6-Epoxyeicosatrienoic acid degrades into 5,6-DiHET and 5,6-δ-lactone, which can be converted to 5,6-DiHET and quantified by GC-MS. In neuroendocrine cells, such as the anterior pituitary and pancreatic islets, 5,6-Epoxyeicosatrienoic acid has been implicated in the mobilization of calcium and hormone secretion. 5,6-Epoxyeicosatrienoic acid is an inhibitor of T-type voltage-gated calcium channels (Cav3) that inhibits isoforms Cav3.1, Cav3.2 (IC₅₀=0.54 μM), and Cav3. and decreases nifedipine-resistant phenylephrine-induced vasoconstriction in isolated mouse mesenteric arteries via Cav3.2 blockade when used at a concentration of 3 μM. In addition, it is a substrate of COX-1 and COX-2, as measured by oxygen consumption and product formation assays when used at a concentration of 50 μM. (±)5,6-Epoxyeicosatrienoic acid is provided as a mixture of the free acid and lactone .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83522

	Growth Hormone 1 Antibody (YA3267) GH1; Somatotropin; Growth hormone; GH; GH-N; Growth hormone 1; pituitary growth hormone	WB, IHC-P, IP	Human
	Growth Hormone 1 Antibody (YA3267) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3267), targeting Growth Hormone 1, with a predicted molecular weight of 25 kDa (observed band size: 25 kDa). Growth Hormone 1 Antibody (YA3267) can be used for WB, IHC-P, IP experiment in human background.

HY-P82172

	Securin Antibody (YA1917) PTTG1; EAP1; PTTG; TUTR1; Securin; Esp1-associated protein; pituitary tumor-transforming gene 1 protein; Tumor-transforming protein 1; hPTTG	WB, IHC-P, IP	Human, Mouse
	Securin Antibody (YA1917) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1917), targeting Securin, with a predicted molecular weight of 22 kDa (observed band size: 25 kDa). Securin Antibody (YA1917) can be used for WB, IHC-P, IP experiment in human, mouse background.

HY-P81526

	VPAC2 Antibody (YA1271) VIP2R; VIPR2; Vasoactive intestinal polypeptide receptor 2; VIP-R-2; Helodermin-preferring VIP receptor; pituitary adenylate cyclase-activating polypeptide type III receptor (PACAP type III receptor; PACAP-R-3; PACAP-R3); VPAC2	IHC-P	Human
	VPAC2 Antibody (YA1271) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1271), targeting VPAC2. VPAC2 Antibody (YA1271) can be used for IHC-P experiment in human background.

HY-P85986

	Chromogranin A Antibody (YA5678) beta Granin; betagranin; N-terminal fragment of chromogranin A; catestatin; CgA; CHG A; Chga; chromofungin; Chromogranin A; Chromogranin A parathyroid secretory protein 1; Chromogranin A precursor; ChromograninA; CMGA_HUMAN; ER-37; Pancreastatin; Parastatin; Parathyroid secretory protein 1; pituitary secretory protein I; Secretory protein I; SP I; SP-I; SP1; SPI; vasostatin 2; Vasostatin; Vasostatin I; Vasostatin II; vasostatin-2	IHC-P, ELISA	Human, Mouse,
	Chromogranin A Antibody (YA5678) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Chromogranin A. It can be applicated for IHC-P, ELISA assays, in the background of human, mouse.

HY-P86527

	Chromogranin A Antibody (YA6219) beta Granin; betagranin; N-terminal fragment of chromogranin A; catestatin; CgA; CHG A; Chga; chromofungin; Chromogranin A; Chromogranin A parathyroid secretory protein 1; Chromogranin A precursor; ChromograninA; CMGA_HUMAN; ER-37; Pancreastatin; Parastatin; Parathyroid secretory protein 1; pituitary secretory protein I; Secretory protein I; SP I; SP-I; SP1; SPI; vasostatin 2; Vasostatin; Vasostatin I; Vasostatin II; vasostatin-2	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Chromogranin A Antibody (YA6219) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Chromogranin A. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

HY-P85880

	Chromogranin A Antibody (YA5572) beta Granin antibody; betagranin; N-terminal fragment of chromogranin A; antibody; catestatin antibody; CgA antibody; CHG A antibody; Chga antibody; chromofungin antibody; Chromogranin A antibody; Chromogranin A parathyroid secretory protein 1 antibody; Chromogranin A precursor antibody; ChromograninA antibody; CMGA_HUMAN antibody; ER-37 antibody; Pancreastatin antibody; Parastatin antibody; Parathyroid secretory protein 1 antibody; pituitary secretory protein I antibody; Secretory protein I antibody; SP I antibody; SP-I antibody; SP1 antibody; SPI antibody; vasostatin 2 antibody; Vasostatin antibody; Vasostatin I antibody; Vasostatin II antibody; vasostatin-2 antibody;	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
	Chromogranin A Antibody (YA5572) is a mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Chromogranin A. It can be applicated for IHC-P, WB, ICC/IF, ELISA assays, in the background of human, mouse, rat.