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Results for "

lysosome

" in MedChemExpress (MCE) Product Catalog:

By Targets:	LYTACs (5) 5-HT Receptor (3) ADC Linker (1) Adrenergic Receptor (3) AMPK (1) Amyloid-β (5) Annexin A (2) Antibiotic (10) Antibody-Drug Conjugates (ADCs) (2) Apoptosis (17) Atg8/LC3 (4) ATTECs (3) AUTACs (3) Autophagy (48) Bacterial (10) Bcl-2 Family (2) Biochemical Assay Reagents (9) Caspase (3) CDK (4) COX (4) DAPK (1) Discoidin Domain Receptor (1) DNA Alkylator/Crosslinker (1) Dopamine Receptor (3) Dopamine Transporter (2) EGFR (5) Endogenous Metabolite (2) Epigenetic Reader Domain (2) Ferroptosis (5) Fluorescent Dye (17) Fungal (2) Glutathione Peroxidase (1) Glycosidase (7) HDAC (5) Histamine Receptor (3) HIV (1) HSP (1) IKK (1) Influenza Virus (1) Isotope-Labeled Compounds (7) Kallikrein (1) Keap1-Nrf2 (1) Lipase (1) Lipocalin Family (1) MDM-2/p53 (1) Mitophagy (3) Mitosis (1) mTOR (2) NF-κB (2) P-glycoprotein (1) p62 (1) PARP (1) PD-1/PD-L1 (3) Phosphodiesterase (PDE) (1) Photosensitizer (1) PIKfyve (1) Pim (1) Potassium Channel (2) Prostaglandin Receptor (1) PROTACs (6) Proton Pump (2) Reactive Oxygen Species (ROS) (6) Reference Standards (5) Ser/Thr Protease (3) SHP2 (1) Sigma Receptor (3) Thrombin (1) TNF Receptor (1) Topoisomerase (1) Transferrin Receptor (1) TRP Channel (1) VSV (1) YAP (1) α-synuclein (3)
By Research Areas:	Cancer (84) Cardiovascular Disease (6) Endocrinology (3) Infection (12) Inflammation/Immunology (18) Metabolic Disease (8) Neurological Disease (21)
Click Chemistry:	DBCO (1)

147

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

INSA	Fluorescent Dye	Others
INSA is a a pH-sensitive fluorescent probe. INSA can simultaneously light up mitochondria (red emission) and lysosomes (green emission) for their internal pH differences .

MHI-148	Fluorescent Dye	Cancer
MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells .

tri-GalNAc biotin	LYTACs	Metabolic Disease
tri-GalNAc biotin is a biotinylated ASGPR (Asialoglycoprotein receptor) ligand. tri-GalNAc biotin promotes cellular uptake of neutravidin (NA) via ASGPR. tri-GalNAc biotin delivers neutravidin to lysosomes for degradation. tri-GalNAc biotin can be used for research of LYsosome TArgeting Chimera (LYTAC) .

ROC-325 1 Publications Verification	Autophagy Apoptosis	Cancer
ROC-325 is a potent and orally active autophagy inhibitor with a strong anticancer activity. ROC-325 induces the deacidification of lysosomes, accumulation of autophagosomes, and disrupted autophagic flux. ROC-325 also induces renal cell carcinoma apoptosis .

HEPES sodium 5+ Cited Publications	Biochemical Assay Reagents	Others
HEPES sodium, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES sodium is effective at pH 6.8 to 8.2. HEPES sodium is also a potent inducer of lysosome biogenesis .

HEPES 5+ Cited Publications	Biochemical Assay Reagents	Others
HEPES, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is also a potent inducer of lysosome biogenesis .

*Autophagy-lysosome* activator-1**	Autophagy	Cancer
Autophagy-lysosome activator-1 (Compound F1) is a *Autophagy-lysosome* activator. Autophagy-lysosome activator-1 effectively induces PD-L1 or VISTA degradation in tumor cells .

Lyso Flipper-TR 29	Fluorescent Dye	Others
Lyso Flipper-TR 29 is a Flipper probe that can label lysosomes. Lyso Flipper-TR 29 enters lysosomes and late endosomes by transient deprotonation to cross their membranes in neutral form .

PMBD	Fluorescent Dye	Others
PMBD is a lysosome (Lyso)-targeting fluorescent probe. PMBD selectively and sensitively detects endogenous N-acylethanolamine amidase (NAAA), allowing real-time visual monitoring of endogenous NAAA in living cells. PMBD has a maximum absorption peak at 350 nm. After the metabolism of NAAA, the maximum absorption peak of the product AMBD shifts red to 450 nm, and a significant fluorescence emission signal appears at 550 nm .

H1k	Autophagy CDK	Cancer
H1k, a Eudistomin Y derivative, is a lysosome-targeted antiproliferation agent. H1k increases the autophagy signal and downregulate the expression of cyclin-dependent kinase (CDK1) and cyclin B1. H1k can be used in research of cancer .

Ammonium chloride, AR, 99.5% 20+ Cited Publications	Autophagy	Cancer
Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor .

LysoTracker Red 5+ Cited Publications LysoTracker Red DND-99	Biochemical Assay Reagents Fluorescent Dye	Others
LysoTracker Red is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .

Green DND-26 1 Publications Verification	Fluorescent Dye	Others
Green DND-26 is a green fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 504/511 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and generally gather on spherical organelles. Green DND-26 is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .

PNE-Lyso	Fluorescent Dye	Others
PNE-Lyso is a activatable fluorescent probe. PNE-Lyso can be used to detect intracellular pH and hexosaminidases with two kinds of fluorescence signals. PNE-Lyso can be used to distinguish apoptosis from necrosis through visualizing lysosome morphology. PNE-Lyso is capable of investigating the agent-induced cell death process .

LysoSensor PDMPO 1 Publications Verification	Fluorescent Dye	Metabolic Disease
PDMPO, a lysosome pH indicator, is an excellent fluorescent acidotropic reagent for fluorescence imaging. PDMPO is a potent tool with which to study acidic organelles of live cells. PDMPO exhibits pH-dependent dual-excitation and dual-emission spectral peaks. PDMPO produces a blue fluorescence in weakly acidic organelles and shifts to yellow in more acidic lysosomes (Abs=329 nm; Em=440 nm) .

Indomethacin-d4 Indometacin-d₄	Isotope-Labeled Compounds COX Autophagy	Inflammation/Immunology Cancer
Indomethacin-d₄ is a deuterium labeled Indomethacin. Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2, with IC₅₀s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells . Indomethacin disrupts autophagic flux by disturbing the normal functioning of lysosomes .

TFEB activator 3	Amyloid-β	Neurological Disease
TFEB activator 3 (compound 45) exhibits TFEB activation and lysosome biogenesis capabilities. TFEB activator 3 has effect on TFEB nuclear translocation with 44% (10μM 3h) and 97 % (30 μM 3h). TFEB activator 3 plays an important role in Alzheimer’s disease (AD). TFEB activator 3 can pass blodd brain barrier .

Ammonium chloride, for cell culture 20+ Cited Publications Salmiac, for cell culture	Biochemical Assay Reagents Autophagy	Cancer
Ammonium chloride, for cell culture (Salmiac, for cell culture) is a reagent that can be used in cell culture to provide a source of nitrogen. Ammonium chloride can be used as a heteropolar compound to regulate pH value, which can cause intracellular alkalination and metabolic acidosis, thus affecting the activity of enzymes and affecting the process of biological systems. Ammonium chloride acts as an autophagy inhibitor.Ammonium chloride is also a lysosome inhibitor.

Siramesine fumarate LU-28-179 fumarate	Sigma Receptor	Cancer
Siramesine (Lu 28-179) fumarate is a potent sigma-2 receptor agonist. Siramesine fumarate has a subnanomolar affinity for sigma-2 receptors (IC₅₀=0.12?nM) and exhibits a 140-fold selectivity for sigma-2 receptors over sigma-1 receptors (IC₅₀=17?nM). Siramesine fumarate triggers cell death through destabilisation of mitochondria, but not lysosomes. Anti-cancer activity .

Siramesine Lu 28-179	Sigma Receptor	Cancer
Siramesine (Lu 28-179) is a potent sigma-2 receptor agonist. Siramesine has a subnanomolar affinity for sigma-2 receptors (IC₅₀=0.12 nM) and exhibits a 140-fold selectivity for sigma-2 receptors over sigma-1 receptors (IC₅₀=17 nM). Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes. Anti-cancer activity .

Siramesine hydrochloride 5 Publications Verification Lu 28-179 hydrochloride	Sigma Receptor Ferroptosis	Cancer
Siramesine (Lu 28-179) hydrochloride is a potent sigma-2 receptor agonist. Siramesine hydrochloride has a subnanomolar affinity for sigma-2 receptors (IC₅₀=0.12 nM) and exhibits a 140-fold selectivity for sigma-2 receptors over sigma-1 receptors (IC₅₀=17 nM). Siramesine hydrochloride triggers cell death through destabilisation of mitochondria, but not lysosomes. Anti-cancer activity .

15(R)-PTA2 15(R)-Pinanethromboxane A2	Prostaglandin Receptor	Cardiovascular Disease
15(R)-PTA2 (15(R)-Pinanethromboxane A2) is an antithrombotic agent that inhibits platelet aggregation. 15(R)-PTA2 inhibits stable prostaglandin endoperoxide analog-induced constriction of feline coronary arteries and stabilizes hepatic lysosomes. 15(R)-PTA2 also inhibits thromboxane synthase but has no effect on prostacyclin synthase .

PROTAC EGFR degrader 3	EGFR PROTACs	Cancer
PROTAC EGFR degrader 3 is a potent PROTAC EGFR degrader. PROTAC EGFR degrader 3 shows excellent cellular activity against the H1975 and HCC827 cells with high selectively. PROTAC EGFR degrader 3 shows that the lysosome is involved in the degradation process of EGFR mutant degradation .

TFEB activator 2	Amyloid-β Dopamine Transporter CDK Autophagy	Neurological Disease
TFEB activator 2 is an orally active compound that can cross the blood-brain barrier. TFEB activator 2 can bind to the dopamine transporter (DAT). TFEB activator 2 promotes TFEB nuclear translocation and lysosome biogenesis by targeting the DAT-CDK9-TFEB pathway. TFEB activator 2 has neuroprotective activity and can be used in the research of Alzheimer's disease and other diseases .

CQ-Lyso	Fluorescent Dye	Cancer
CQ-Lyso is a lysosome-targeting chromenoquinoline. CQ-Lyso is a fluorescent probe for measuring the pH of lysosomes in living cells using only single wavelength excitation. CQ-Lyso can visualize the dynamic pH changes in lysosomes .

RH1115	Autophagy	Neurological Disease
RH1115 (compound 2c) is a modulator of the autophagy-lysosome. RH1115 induces changes to LAMP1 vesicle properties and alters lysosome positioning .

Autophagy-IN-1	Autophagy Apoptosis	Cancer
Autophagy-IN-1 is a potent autophagy/mitophagy inhibitor, acts by selectively increasing the autophagic flux while blocking the autophagosome-lysosome fusion in cancer cells. Autophagy-IN-1 can induce apoptosis and cell cycle arrest. Autophagy-IN-1 significantly inhibits tumor growth in an HCT116 xenograft mouse model and with low toxicity. Autophagy-IN-1 can be used for researching colorectal cancer .

Ferrostatin-1 diyne Fer-1 diyne	Ferroptosis	Cancer
Ferrostatin-1 diyne (Fer-1 diyne) (compound 2) is a ferroptosis inhibitor that accumulates in lysosomes, mitochondria, and endoplasmic reticulum in cells, but its inhibition of ferroptosis is not dependent on the activity of lysosomes and mitochondria.

OsMo	Reactive Oxygen Species (ROS) Autophagy	Cardiovascular Disease
OsMo is a lysosome-targeting hNEU1 inhibitor that can be used in the study of myocardial injury .

tri-GalNAc-COOH	LYTACs	Cancer
tri-GalNAc-COOH is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research .

HCy-Lyso	Fluorescent Dye	Others
HCy-Lyso is a lysosome-targeting turn-on fluorescent probe based on hydrocyanine. HCy-Lyso integrates a hydrocyanine moiety for selective recognition of hydroxyl radicals (•OH) and a morpholine group for lysosome targeting. Upon reacting with •OH, HCy-Lyso undergoes an extension of its π-conjugation system, producing a strong fluorescence signal at 598 nm when excited at 510 nm .

Nitro-coronene	Biochemical Assay Reagents	Cancer
Nitro-coronene can be used to prepare near-infrared light-triggered lysosome-targetable carbon dots for photothermal research of cancer.

Fimaporfin TPCS2a	Fluorescent Dye	Cancer
Fimaporfin (TPCS2a) is a photosensitizer that localizes to endosomes/lysosomes with an excitation wavelength of 420 nm and an emission wavelength between 640 and 680 nm .

Neutral Red	Fluorescent Dye	Others
Neutral Red, a nitrogenous pH-indicator with a pK_i of 6.8, is an indicator for the internal acidification of thylakoids. Neutral Red stains lysosomes red .

CTB probe-1	Fluorescent Dye	Others
CTB probe-1 (probe 1) a lysosome-targeting fluorogenic small-molecule probe for fluorescence imaging in living cells .

Bafilomycin A1 Maximum Cited Publications 591 Publications Verification BafA1	Proton Pump Autophagy Antibiotic Bacterial Apoptosis	Infection Cancer
Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H ⁺-ATPase (V-ATPase) with IC₅₀ values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis .

LH2-051	Dopamine Transporter CDK	Neurological Disease
LH2-051 is a lysosome-enhancing lead compound, which promotes the lysosome biogenesis and the Aβ aggregate clearance through dopamine transporter-cyclin-dependent kinase 9-transcription factor EB (DAT-CDK9-TFEB) pathway. LH2-051 exhibits good pharmacokinetic characteristics in mouse models. LH2-051 is potential for ameliorating Aleheimer’s Disease .

Cholesteryl behenate 1 Publications Verification Cholesteryl docosanoate; Cholesterol behenate	Endogenous Metabolite	Metabolic Disease
Cholesteryl behenate is a cholesterol ester associated with the neutral core of low density lipoprotein Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters.

CUR5g	Autophagy	Cancer
CUR5g is a potent autophagy inhibitor. CUR5g selectively inhibits autophagosome degradation in cancer cells by blocking autophagosome-lysosome fusion. CUR5g blocks the recruitment of STX17 to autophagosomes via a UVRAG-dependent mechanism, resulting in the inability of autophagosomes to fuse with lysosomes. CUR5g improves the anticancer effect of Cisplatin (HY-17394) against A549 cells both in vitro and in vivo .

MHY1485 155+ Cited Publications	mTOR Autophagy	Cancer
MHY1485 is a potent cell-permeable mTOR activator that targets the ATP domain of mTOR. MHY1485 inhibits autophagy by suppression of fusion between autophagosomes and lysosomes .

Dehydropachymic acid	Autophagy	Neurological Disease
Dehydropachymic acid is one of the major triterpenes isolated from Poria cocos. Dehydropachymic acid is more effective in autophagy-lysosome pathway (ALP) impaired cells rather than normal cells .

Euphorblin R EOF2	Others	Metabolic Disease
Euphorblin R (EOF2) is a rhamnyl diterpenoid isolated from Euphorbia resinifera. Euphorblin R may promote lysosomal biogenesis and has the potential to be used in the study of lysosome-related diseases.

EACC 3 Publications Verification	Autophagy	Infection Neurological Disease
EACC is a reversible autophagy inhibitor, which can block autophagic flux. EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion .

Biguanidinium-porphyrin	Photosensitizer	Others
Biguanidinium-porphyrin is a mitochondria-targeting photosensitizer. Biguanidinium-porphyrin distributes within cell membranes with a large component in vesicles that correlated to some extent with the lysosomes and, upon longer exposures, in mitochondria and the cytosolic membrane .

PDL1 degrader-2	PD-1/PD-L1 Autophagy AUTACs	Cancer
PD-L1 degrader-2 (Compound B3) is an orally active AUTAC degrader, that degrades PD-L1 through autophagy-lysosome pathway with a DC₅₀ of 0.5 μM. PD-L1 degrader-2 exhibits inhibitory activity against PD-1/PD-L1 interaction with an IC₅₀ of 22.8 nM. PD-L1 degrader-2 upregulates the expressions of Atg9b, Lamp1 and Mitf, and activates the autophagy lysosome system. PD-L1 degrader- exhibits antitumor efficacy in CT26 mouse model . (Pink: autophagy-lysosome activator (HY-159894); Black: linker (HY-W015088); Blue: PD-L1 ligand (HY-169365))

MK6-83	TRP Channel	Metabolic Disease
MK6-83 is a new candidate agonist of TRPML1 with an improved efficacy and potency. MK6-83 has the potential for Mucolipidosis type IV study .

Cat. No.	Product Name

HY-L029

Autophagy Compound Library

1,663 compounds

Autophagy is a lysosomal degradation pathway that is essential for cell survival, differentiation, development, and homeostasis. The process of autophagy in mammalian cells is as follows: a portion of cytoplasm, including organelles, is enclosed by a phagophore or isolation membrane to form an autophagosome. The outer membrane of the autophagosome subsequently fuses with the endosome and then the lysosome, and the internal material is degraded. Autophagy plays a wide variety of physiological and pathophysiological roles. Defective autophagy contributes to various pathologies, including infections, cancer, neurodegeneration, aging, and heart disease.

MCE provides a unique collection of 1,663 autophagy pathway-related compounds that is a useful tool for the research of autophagy-related regulation and diseases.

HY-L162

Cell Death Library

3,060 compounds

Cell death plays a crucial role in the development of the body and the maintenance of internal balance to prevent the development of diseases. According to the regulation of the involved processes, cell death can be defined as programmed and non-programmed death. Programmed cell death (PCD) can be divided into lytic cell death and nonlytic cell death, mainly including apoptosis, necrotic apoptosis and Pyroptosis. Non-Programmed cell death (Non-PCD) generally refers to necrosis. In stark contrast to Accidental Cell Death (ACD), Regulatory Cell Death (RCD) relies on specialized molecular mechanisms. Cell death includes internal apoptosis, external apoptosis, necrotic apoptosis, ferroptosis, pyroptosis, lysosome-dependent cell death, etc.

MCE designs a unique collection of 3,060 cell death compounds, covering multiple targets, such as Apoptosis, Ferroptosis, Pyroptosis, Necroptosis, etc. It is a useful tool for screening cell death drugs.

HY-L050

Ubiquitination Compound Library

360 compounds

Protein ubiquitination is an enzymatic post-translational modification in which an ubiquitin protein is attached to a substrate protein. Ubiquitination involves three main steps: activation, conjugation, and ligation, performed by ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin ligases (E3s), respectively. Ubiquitination affects cellular processes such as apoptosis, cell cycle, DNA damage repair, and membrane transportation, etc. by regulating the degradation of proteins (via the proteasome and lysosome), altering the cellular localization of proteins, affecting proteins activity, and promoting or preventing protein-protein interactions. Deregulation of ubiquitin pathway leads to many diseases such as neurodegeneration, cancer, infection and immunity, etc.

MCE offers a unique collection of 360 small molecule modulators with biological activity used for ubiquitination research. Compounds in this library target the key enzymes in ubiquitin pathway. MCE Ubiquitination Compound Library is a useful tool for the research of ubiquitination regulation and the corresponding diseases.

Cat. No.	Product Name	Type

HY-157036

INSA	Fluorescent Dyes/Probes
INSA is a a pH-sensitive fluorescent probe. INSA can simultaneously light up mitochondria (red emission) and lysosomes (green emission) for their internal pH differences .

HY-D1711

MHI-148	Dyes
MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells .

HY-D1300

LysoTracker Red Maximum Cited Publications 7 Publications Verification LysoTracker Red DND-99	Dyes
LysoTracker Red is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .

HY-D1296

Green DND-26 1 Publications Verification	Fluorescent Dyes/Probes
Green DND-26 is a green fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 504/511 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and generally gather on spherical organelles. Green DND-26 is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes .

HY-D1445

LysoSensor PDMPO 1 Publications Verification	Fluorescent Dyes/Probes
PDMPO, a lysosome pH indicator, is an excellent fluorescent acidotropic reagent for fluorescence imaging. PDMPO is a potent tool with which to study acidic organelles of live cells. PDMPO exhibits pH-dependent dual-excitation and dual-emission spectral peaks. PDMPO produces a blue fluorescence in weakly acidic organelles and shifts to yellow in more acidic lysosomes (Abs=329 nm; Em=440 nm) .

HY-D2119

CQ-Lyso	Fluorescent Dyes/Probes
CQ-Lyso is a lysosome-targeting chromenoquinoline. CQ-Lyso is a fluorescent probe for measuring the pH of lysosomes in living cells using only single wavelength excitation. CQ-Lyso can visualize the dynamic pH changes in lysosomes .

HY-D0166

Neutral Red	Dyes
Neutral Red, a nitrogenous pH-indicator with a pK_i of 6.8, is an indicator for the internal acidification of thylakoids. Neutral Red stains lysosomes red .

HY-D2321

Lyso Flipper-TR 29	Fluorescent Dyes/Probes
Lyso Flipper-TR 29 is a Flipper probe that can label lysosomes. Lyso Flipper-TR 29 enters lysosomes and late endosomes by transient deprotonation to cross their membranes in neutral form .

HY-D2338

PMBD

Fluorescent Dyes/Probes

PMBD is a lysosome (Lyso)-targeting fluorescent probe. PMBD selectively and sensitively detects endogenous N-acylethanolamine amidase (NAAA), allowing real-time visual monitoring of endogenous NAAA in living cells. PMBD has a maximum absorption peak at 350 nm. After the metabolism of NAAA, the maximum absorption peak of the product AMBD shifts red to 450 nm, and a significant fluorescence emission signal appears at 550 nm .

HY-151544

PNE-Lyso	Fluorescent Dyes/Probes
PNE-Lyso is a activatable fluorescent probe. PNE-Lyso can be used to detect intracellular pH and hexosaminidases with two kinds of fluorescence signals. PNE-Lyso can be used to distinguish apoptosis from necrosis through visualizing lysosome morphology. PNE-Lyso is capable of investigating the agent-induced cell death process .

HY-D2254

CTB probe-1	Fluorescent Dyes/Probes
CTB probe-1 (probe 1) a lysosome-targeting fluorogenic small-molecule probe for fluorescence imaging in living cells .

HY-D2449

DQ-BSA-RED

Dyes

DQ-BSA-Red is a bovine serum albumin labeled with a red fluorescent dye that can be used to detect lysosomal activity. The excitation wavelength and emission wavelength of DQ-BSA-Red are 590 nm and 620 nm, respectively. The BSA molecule in DQ-BSA-Red is labeled with high concentration of red fluorescent dye in multiple sites, which shows high fluorescence self-inhibition. Once DQ-BSA-RED enters the lysosome, DQ-BSA is cleaved by lysosomal proteases, resulting in unquenched and released fluorescent fragments, emitting bright fluorescence. Inactivated lysosomes are unable to degrade the BSA protein and thus have a lower or even no fluorescent signal .

HY-169130

Lyso BD-1	Fluorescent Dyes/Probes
Lyso BD-1, preferentially colocalized in lysosomes and lipid droplets, displays excellent photocytotoxicity (5.57 μM) on triple negative breast cancer cells under white light. Lyso BD-1 displays emission band at 560nm .

Cat. No.	Product Name	Type

HY-108535

HEPES sodium 5+ Cited Publications	Buffer Reagents
HEPES sodium, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES sodium is effective at pH 6.8 to 8.2. HEPES sodium is also a potent inducer of lysosome biogenesis .

HY-D0857

HEPES 5+ Cited Publications	Buffer Reagents
HEPES, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is also a potent inducer of lysosome biogenesis .

HY-Y1269

Ammonium chloride, AR, 99.5% Maximum Cited Publications 25 Publications Verification	Buffer Reagents
Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor .

HY-Y1269C

Ammonium chloride, for cell culture

Maximum Cited Publications

25 Publications Verification

Salmiac, for cell culture

Buffer Reagents

Ammonium chloride, for cell culture (Salmiac, for cell culture) is a reagent that can be used in cell culture to provide a source of nitrogen. Ammonium chloride can be used as a heteropolar compound to regulate pH value, which can cause intracellular alkalination and metabolic acidosis, thus affecting the activity of enzymes and affecting the process of biological systems. Ammonium chloride acts as an autophagy inhibitor.Ammonium chloride is also a lysosome inhibitor.

HY-138540

1-Dodecylimidazole 1 Publications Verification N-Dodecylimidazole	Cell Assay Reagents
1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity .

HY-Y1269D

Ammonium chloride, for molecular biology

Salmiac, for molecular biology

Buffer Reagents

Ammonium chloride, for molecular biology is ammonium chloride that can be used for molecular biology research. Ammonium chloride can be used as a heteropolar compound to regulate pH value, which can cause intracellular alkalination and metabolic acidosis, thus affecting the activity of enzymes and affecting the process of biological systems. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor .

HY-Y1269H

Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC

Salmiac, meets analytical specification of Ph. Eur. BP USP FCC

Buffer Reagents

Ammonium chloride, meets analytical specification of Ph. Eur. BP USP FCC (Salmiac, meets analytical specification of Ph. Eur. BP USP FCC) can be used as a heteropolar compound to regulate pH value, which can cause intracellular alkalination and metabolic acidosis, thus affecting the activity of enzymes and affecting the process of biological systems. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor .

HY-Y1269I

Ammonium chloride, United States Pharmacopeia (USP) Reference Standard

Salmiac (Pharmaceutical primary standard, USP)

Buffer Reagents

Ammonium chloride United States Pharmacopeia (USP) Reference Standard (Salmiac, Pharmaceutical primary standard, USP) is a reagent that can be used in cell culture to provide a source of nitrogen. Ammonium chloride can be used as a heteropolar compound to regulate pH value, which can cause intracellular alkalination and metabolic acidosis, thus affecting the activity of enzymes and affecting the process of biological systems. Ammonium chloride is also a lysosome inhibitor .

HY-138540R

1-Dodecylimidazole (Standard)

Cell Assay Reagents

1-Dodecylimidazole (Standard) is the analytical standard of 1-Dodecylimidazole. This product is intended for research and analytical applications. 1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity .

Cat. No.	Product Name	Target	Research Area

HY-P1098

Ac2-26 Maximum Cited Publications 6 Publications Verification	Annexin A NF-κB	Inflammation/Immunology
Ac2-26 is the N-terminal peptide of annexin 1, and has anti-inflammatory activity. Ac2-26 induces a decrease in IKKβ protein in lysosomes by chaperone-mediated autophagy (CMA). Ac2-26 ameliorates lung ischemia-reperfusion injury. Ac2-26 also inhibits airway inflammation and hyperresponsiveness in an asthma rat model .

HY-P1098A

Ac2-26 TFA Maximum Cited Publications 6 Publications Verification	Annexin A NF-κB	Inflammation/Immunology
Ac2-26 TFA is the N-terminal peptide of annexin 1, and has anti-inflammatory activity. Ac2-26 induces a decrease in IKKβ protein in lysosomes by chaperone-mediated autophagy (CMA). Ac2-26 ameliorates lung ischemia-reperfusion injury. Ac2-26 also inhibits airway inflammation and hyperresponsiveness in an asthma rat model .

HY-P1098B

Ac2-26 ammonium Maximum Cited Publications 6 Publications Verification	IKK	Inflammation/Immunology
Ac2-26 ammonium is the N-terminal peptide of annexin 1, and has anti-inflammatory activity. Ac2-26 ammonium induces a decrease in IKKβ protein in lysosomes by chaperone-mediated autophagy (CMA). Ac2-26 ammonium ameliorates lung ischemia-reperfusion injury. Ac2-26 ammonium also inhibits airway inflammation and hyperresponsiveness in an asthma rat model .

HY-P10669

NDI-Lyso	Caspase Apoptosis	Cancer
NDI-Lyso is a lysosome-targeted anticancer agent that induces the formation of rigid long fibers in cancer cell lysosomes through an enzyme-instructed self-assembly (EISA) mechanism catalyzed by cathepsin B. This process triggers lysosomal swelling, membrane permeabilization (LMP), and membrane disruption, ultimately leading to cancer cell apoptosis via a non-classical caspase-independent pathway. NDI-Lyso exhibits significant selective anticancer activity in various cancer cell lines and drug-resistant cancer cells (IC₅₀ ~10 μM) while showing low toxicity to normal cells (IC₅₀ > 60 μM) .

HY-P5277

TAT-GluN2BCTM	DAPK	Neurological Disease
TAT-GluN2BCTM is a membrane-permeable DAPK1-targeting peptide. TAT-GluN2BCTM targets active DAPK1 to lysosomes for degradation. TAT-GluN2BCTM protects neurons from oxidative stress and NMDAR-mediated excitotoxicity by knocking down DAPK1. TAT-GluN2BCTM can be used in the study of neuroprotection .

HY-P10404

PDpep1.3	α-synuclein	Others Neurological Disease
PDpep1.3 is a peptide inhibitor of α-synuclein that disrupts the direct interaction between α-synuclein and CHarged Multivesicular body Protein 2B (CHMP2B). As a result, PDpep1.3 restores the degradation function of endosomes and lysosomes, reduces the protein level and aggregation of α-synuclei, and protects dopaminergic neurons from α-synuclei-mediated degeneration. PDpep1.3 can be used to study neurodegenerative diseases and protein-protein interactions .

Cat. No.	Product Name

HY-KD1027

Lyso Green Kit
Lyso Green is a fluorescent probe with green fluorescence for specific labeling of lysosomes in living mammalian cells.

HY-KD1028

Lyso Red Kit
Lyso Red is a fluorescent probe with red fluorescence for specific labeling of lysosomes in living mammalian cells.

HY-KD1026

Lyso Deep Red Kit
Lyso Deep Red is a fluorescent probe with deep red fluorescence for specific labeling of lysosomes in living mammalian cells.

Cat. No.	Product Name	Target	Research Area

HY-P99956

Zilovertamab vedotin VLS-101; MK-2140	Antibody-Drug Conjugates (ADCs) Apoptosis	Cancer
Zilovertamab vedotin (VLS-101) is a novel antibody-drug conjugate comprising the humanized monoclonal antibody zilovertamab and and the anti-microtubule cytotoxin monomethyl vedotin. Zilovertamab vedotin binding to tumor cell ROR1 results in rapid internalization, trafficking to lysosomes, antibody–agent conjugate cleavage, and monomethyl vedotin release. Zilovertamab vedotin induces apoptosis. Zilovertamab vedotin can be used in research of cancer .

HY-P99683

Ladiratuzumab vedotin SGN-LIV1A	Antibody-Drug Conjugates (ADCs)	Cancer
Ladiratuzumab vedotin (SGN-LIV1A) is a LIV-1 targeting antibody drug conjugate (ADC) (IC₅₀: 5.6 nM for LIV-1). Ladiratuzumab vedotin consists of humanized IgG1 monoclonal antibody, MMAE and a protease-cleavable linker. Ladiratuzumab vedotin can drive immunogenic cell death (ICD) to elicit an immune response. Ladiratuzumab vedotin can be used for research of breast cancer .

HY-P991236

MHES0488A DHES0815A antibody; RG-6148 antibody	EGFR DNA Alkylator/Crosslinker	Cancer
MHES0488A is a selective humanized antibody that targets HER2 with a K_D value of 0.8 nM. MHES0488A is an antibody part of DHES0815A. MHES0488A is internalized by cells and transported to lysosomes, and then releases PBD-monoamide that enters the nucleus, alkylates DNA and induces DNA damage and apoptosis. MHES0488A is promising for research of cancers, such as HER2-positive breast cancer and gastric cancer .

HY-P99803

Clervonafusp alfa VAL-1221	Glycosidase	Others
Clervonafusp alfa (VAL-1221) is a fusion protein targeting both cytosolic and lysosomal glycogen. Clervonafusp alfa is comprised of the Fab portion of a cell-penetrating antibody and recombinant human acid alpha glucosidase (rhGAA), the former utilizing the nucleoside transporter ENT-2 to gain access to the cytosol, and the latter enters lysosomes via mannose-6-phosphate receptors (M6PRs). Clervonafusp alfa can be used for late-onset Pompe disease research .

Species:	Human (9) Rhesus Macaque (1) Mouse (3) Rat (1) Cynomolgus (1)
Tag:	His (11) Tag Free (1) Avi (1) GST (1) Fc (2)
Source:	HEK293 (12) E. coli (2) sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P7778

	LAMP1/CD107a Protein, Human (HEK293, His) rHuCD107a, His; lysosome-Associated Membrane Glycoprotein 1; LAMP-1; lysosome-Associated Membrane Protein 1; CD107 Antigen-Like Family Member A; CD107a; LAMP1	Human	HEK293
	LAMP1/CD107a Protein, Human (HEK293, His) is a recombinant human CD107a expressed in HEK 293 cells with a His tag at the N-terminus. LAMP1/CD107a Protein can be used as a functional marker for the identification of natural killer cell activity.

HY-P7779

	LAMP1/CD107a Protein, Human (HEK293, Fc) rHuCD107a, C-Fc; lysosome-Associated Membrane Glycoprotein 1; LAMP-1; lysosome-Associated Membrane Protein 1; CD107 Antigen-Like Family Member A; CD107a; LAMP1	Human	HEK293
	LAMP1/CD107a Protein, Human (HEK293, Fc) is a recombinant human CD107a expressed in HEK 293 cells with a C-Fc tag at the C-terminus. LAMP1/CD107a Protein can be used as a functional marker for the identification of natural killer cell activity.

HY-P77435

	LAMP3/CD208 Protein, Human (HEK293, His) lysosome-associated membrane glycoprotein 3; LAMP-3; DCLAMP; TSC403	Human	HEK293
	LAMP3/CD208 is a lysosomal glycoprotein that participates in the unfolded protein response (UPR) and contributes to protein degradation and cell survival, especially in the presence of proteasome dysfunction.It crucially promotes lysosome-autophagosome fusion and regulates autophagy.LAMP3/CD208 Protein, Human (HEK293, His) is the recombinant human-derived LAMP3/CD208 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74781

	LAMP2/CD107b Protein, Mouse (HEK293, His) lysosome-Associated Membrane Glycoprotein 2; LAMP-2; CD107b	Mouse	HEK293
	The LAMP2/CD107b protein is a lysosomal membrane glycoprotein critical for lysosomal biogenesis, pH regulation, and autophagy.As a direct inhibitor of TMEM175, LAMP2 promotes lysosomal acidification and optimizes hydrolase activity.LAMP2/CD107b Protein, Mouse (HEK293, His) is the recombinant mouse-derived LAMP2/CD107b protein, expressed by HEK293 , with C-His labeled tag.

HY-P74782

	LAMP1/CD107a Protein, Rat (HEK293, Fc) lysosome-Associated Membrane Glycoprotein 1; LAMP-1; CD107a	Rat	HEK293
	The LAMP1/CD107a protein is a lysosomal membrane glycoprotein that plays critical roles in lysosomal biogenesis, pH regulation, autophagy, and cholesterol homeostasis.It critically regulates lysosomal lumen pH by inhibiting the proton channel TMEM175, optimizing lysosomal acidification for efficient hydrolase activity.LAMP1/CD107a Protein, Rat (HEK293, Fc) is the recombinant rat-derived LAMP1/CD107a protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77436

	LAMP3/CD208 Protein, Rhesus Macaque (HEK293, His) lysosome-associated membrane glycoprotein 3; LAMP-3; DCLAMP; TSC403	Rhesus Macaque	HEK293
	The LAMP3/CD208 protein is a lysosomal membrane glycoprotein that actively participates in the unfolded protein response (UPR), aiding protein degradation and cell survival during proteasome dysfunction. It is essential for lysosome-autophagosome fusion, where it regulates the autophagy process. LAMP3/CD208 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived LAMP3/CD208 protein, expressed by HEK293 , with C-His labeled tag.

HY-P71278

	SCARB2/LIMP-2 Protein, Human (HEK293, His) lysosome Membrane Protein 2; 85 kDa Lysosomal Membrane Sialoglycoprotein; LGP85; CD36 Antigen-Like 2; lysosome Membrane Protein II; LIMP II; Scavenger Receptor Class B Member 2; CD36; SCARB2; CD36L2; LIMPII	Human	HEK293
	SCARB2/LIMP-2 Protein functions as a lysosomal receptor, specifically guiding glucosylceramidase (GBA1) to lysosomes. Additionally, it serves as a receptor for enterovirus 71, emphasizing its role in mediating cellular interactions during viral invasion and cellular entry processes. SCARB2/LIMP-2 Protein, Human (HEK293, His) is the recombinant human-derived SCARB2/LIMP-2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P77434

	LAMP2/CD107b Protein, Cynomolgus (HEK293, His) lysosome-Associated Membrane Glycoprotein 2; LAMP-2; CD107b	Cynomolgus	HEK293
	The LAMP2/CD107b protein is part of the LAMP family and is essential for lysosome-associated membrane glycoproteins. Within this family, LAMP2 may play a crucial role in cellular processes involving lysosomal function, vesicle trafficking, and cellular homeostasis. LAMP2/CD107b Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived LAMP2/CD107b protein, expressed by HEK293 , with C-His labeled tag.

HY-P78759

	ELAPOR1 Protein, Human (sf9, His) ELAPOR1; Endosome-lysosome Associated Apoptosis And Autophagy Regulator 1; EIG121; KIAA1324	Human	sf9 insect cells
	The ELAPOR1 protein emerged as a potential cytoprotective agent, inducing cytoplasmic vacuolation and upregulating the autophagy pathway to protect cells from death. ELAPOR1 interacts with HSPA5 and plays dual roles in apoptosis and cell proliferation. ELAPOR1 Protein, Human (sf9, His) is the recombinant human-derived ELAPOR1 protein, expressed by sf9 insect cells , with C-His labeled tag. The total length of ELAPOR1 Protein, Human (sf9, His) is 869 a.a., with molecular weight of 100-120 kDa.

HY-P72515

	LIMPII/SR-B2 Protein, Mouse (406a.a, HEK293, His) lysosome membrane protein 2; LGP85; LIMP II; Scarb2	Mouse	HEK293
	LIMPII/SR-B2 Protein acts as a lysosomal receptor crucial for targeting glucosylceramidase (GBA1) to lysosomes. This interaction highlights its role in intracellular trafficking, ensuring the specific recognition and delivery of GBA1 to the lysosomal environment. The protein's direct interaction with GBA1 contributes to essential cellular processes related to lipid metabolism and degradation. LIMPII/SR-B2 Protein, Mouse (406a.a, HEK293, His) is the recombinant mouse-derived LIMPII/SR-B2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P705139

	ELAPOR1 Protein, Human (Biotinylated, HEK293, His-Avi) ELAPOR1; Endosome-lysosome Associated Apoptosis And Autophagy Regulator 1; EIG121; KIAA1324	Human	HEK293

HY-P72526

	LAMP1/CD107a Protein, Mouse (HEK293, His) lysosome-associated membrane glycoprotein 1; LAMP-1; LGP-A; CD107a; LAMPA; P2B	Mouse	HEK293
	LAMP1/CD107a is a key lysosomal glycoprotein that regulates lysosomal biogenesis, pH, autophagy, and cholesterol homeostasis.It directly inhibits the TMEM175 proton channel, optimizing lysosomal acidity for efficient hydrolase activity.LAMP1/CD107a Protein, Mouse (HEK293, His) is the recombinant mouse-derived LAMP1/CD107a protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76171

	BLOC1S2 Protein, Human Biogenesis of lysosome-related organelles complex 1 subunit 2; BLOC-1 subunit 2; BLOS2; CEAP	Human	E. coli
	BLOC1S2 is an essential component of the BLOC-1 complex and is critical for the biogenesis of lysosome-related organelles (LROs), including platelet dense granules and melanosomes. BLOC-1 cooperates with the AP-3 complex to direct membrane protein cargo into vesicles for delivery to neurites and nerve terminals, suggesting that it is involved in neurite extension. BLOC1S2 Protein, Human (GST) is the recombinant human-derived BLOC1S2 protein, expressed by E. coli , with no tagged.

HY-P72525

	LAMP2/CD107b Protein, Human (HEK293, His) lysosome-Associated Membrane Glycoprotein 2; LAMP-2; CD107 Antigen-Like Family Member B; CD107b	Human	HEK293
	LAMP2 is a key lysosomal glycoprotein that plays crucial roles in lysosomal biogenesis, pH regulation, and autophagy. It directly inhibits the TMEM175 proton channel, optimizing lysosomal acidity for efficient hydrolase activity. LAMP2/CD107b Protein, Human (HEK293, His) is the recombinant human-derived LAMP2/CD107b protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76171A

	BLOC1S2 Protein, Human (N-GST) Biogenesis of lysosome-related organelles complex 1 subunit 2; BLOC-1 subunit 2; BLOS2; CEAP	Human	E. coli
	BLOC1S2 is an essential component of the BLOC-1 complex and is critical for the biogenesis of lysosome-related organelles (LROs), including platelet dense granules and melanosomes. BLOC-1 cooperates with the AP-3 complex to direct membrane protein cargo into vesicles for delivery to neurites and nerve terminals, suggesting that it is involved in neurite extension. BLOC1S2 Protein, Human (N-GST) is the recombinant human-derived BLOC1S2 protein, expressed by E. coli , with N-GST labeled tag.

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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80740

	LAMP2 Antibody (YA310) LAMP2; lysosome-associated membrane glycoprotein 2; LAMP-2; lysosome-associated membrane protein 2; CD107 antigen-like family member B; CD107b	WB, IHC-P	Human
	LAMP2 Antibody (YA310) is a non-conjugated and Rabbit origined monoclonal antibody about 45 kDa, targeting to LAMP2. It can be used for WB,IHC-P assays with tag free, in the background of Human.

HY-P80206

	LAMP1 Antibody (YA311) CD107 antigen like family member A antibody; CD107 antigen-like family member A antibody; CD107a antibody; CD107a antigen antibody; LAMP 1 antibody; LAMP-1 antibody; LAMP1 antibody; LAMP1_HUMAN antibody; LAMPA antibody; LGP120 antibody; lgpA antibody; Lysosomal membrane glycoprotein 120KD antibody; Lysosomal Associated Membrane Protein 1 antibody; lysosome associated membrane glycoprotein 1 antibody; lysosome-associated membrane glycoprotein 1 antibody; lysosome-associated membrane protein 1 antibody; OTTHUMP00000040663 antibody	WB, IHC-P	Human
	LAMP1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 45 kDa, targeting to LAMP1. It can be used for WB,IHC-P assays with tag free, in the background of Human.

HY-P80206A

	LAMP1 Antibody (YA3434) CD107 antigen like family member A antibody; CD107 antigen-like family member A antibody; CD107a antibody; CD107a antigen antibody; LAMP 1 antibody; LAMP-1 antibody; LAMP1 antibody; LAMP1_HUMAN antibody; LAMPA antibody; LGP120 antibody; lgpA antibody; Lysosomal membrane glycoprotein 120KD antibody; Lysosomal Associated Membrane Protein 1 antibody; lysosome associated membrane glycoprotein 1 antibody; lysosome-associated membrane glycoprotein 1 antibody; lysosome-associated membrane protein 1 antibody; OTTHUMP00000040663 antibody;	WB, IHC-P, IHC-F, ICC/IF, IP, IF-Tissue	Human, Mouse, Rat
	LAMP1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 45 kDa, targeting to LAMP1. It can be used for WB, IHC-P, IF-Tissue, IHC-Fr, IP assays with tag free, in the background of Human,Mouse,Rat.

HY-P82822

	Lysosome Membrane Protein 2 Antibody (YA2567) AMRF; CD36; CD36L2; EPM4; HLGP85; LGP85; LIMP2; LIMPII; Scarb2; SRBII	WB, IHC-P, IP, FC	Human, Mouse, Rat
	Lysosome Membrane Protein 2 Antibody (YA2567) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2567), targeting Lysosome Membrane Protein 2, with a predicted molecular weight of 54 kDa (observed band size: 77 kDa). Lysosome Membrane Protein 2 Antibody (YA2567) can be used for WB, IHC-P, IP, FC experiment in human, mouse, rat background.

HY-P86521

	LAMP1 Antibody (YA6213) LAMP1; lysosome-associated membrane glycoprotein 1; LAMP-1; lysosome-associated membrane protein 1; CD107 antigen-like family member A; CD107a	WB, IHC-P, ICC/IF, IP, ELISA	Human
	LAMP1 Antibody (YA6213) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LAMP1. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human.

HY-P86565

	LAMP2 Antibody (YA6257) LAMP2; lysosome-associated membrane glycoprotein 2; LAMP-2; lysosome-associated membrane protein 2; CD107 antigen-like family member B; CD107b	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse
	LAMP2 Antibody (YA6257) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LAMP2. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse.

HY-P84954

	CD107a Antibody (YA4646) LAMP1; lysosome-associated membrane glycoprotein 1; LAMP-1; lysosome-associated membrane protein 1; CD107 antigen-like family member A; CD107a
	CD107a Antibody (YA4646) is a non-conjugated antibody, targeting to CD107a.

HY-P85885

	CD63 Antibody (YA5577) Lysosomal associated membrane protein 3 antibody; CD 63 antibody; CD63 antibody; CD63 antigen; melanoma 1 antigen; antibody; CD63 antigen antibody; CD63 antigen melanoma 1 antigen antibody; CD63 molecule antibody; CD63_HUMAN antibody; gp55 antibody; Granulophysin antibody; LAMP 3 antibody; LAMP-3 antibody; LAMP3 antibody; LIMP antibody; Lysosomal-associated membrane protein 3 antibody; lysosome associated membrane glycoprotein 3 antibody; lysosome-associated membrane glycoprotein 3 antibody; Mast cell antigen AD1 antibody; ME491 antibody; Melanoma 1 antigen antibody; Melanoma associated antigen ME491 antibody; Melanoma associated antigen MLA1 antibody; Melanoma-associated antigen ME491 antibody; MGC72893 antibody; MLA 1 antibody; MLA1 antibody; NGA antibody; Ocular melanoma associated antigen antibody; Ocular melanoma-associated antigen antibody; OMA81H antibody; PTLGP40 antibody; Tetraspanin 30 antibody; Tetraspanin-30 antibody; Tspan 30 antibody; Tspan-30 antibody; TSPAN30 antibody;	IHC-P, WB, ICC/IF, ELISA	Human
	CD63 Antibody (YA5577) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD63. It can be applicated for IHC-P, WB, ICC/IF, ELISA assays, in the background of human.

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Cat. No.	Product Name		Classification

HY-148476

Tri-GalNAc-DBCO		DBCO
Tri-GalNAc-DBCO is a synthetic ligand composed of three GalNAc units linked to DBCO. Tri-GalNAc-DBCO can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing an azide group. Tri-GalNAc-DBCO specifically binds to the asialoglycoprotein receptor (ASGPR). Tri-GalNAc-DBCO directs the conjugated molecule to the lysosome for degradation via receptor-mediated endocytosis. Tri-GalNAc-DBCO can be used in the study of liver-related diseases .

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