Search Result

Results for "

antiviral and anti-inflammatory activities

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (1) 5-HT Receptor (2) ADC Payload (2) Adrenergic Receptor (1) Akt (3) Amyloid-β (6) Antibiotic (10) AP-1 (1) Apoptosis (43) ATP-binding cassette (ABC) transporters (1) Aurora Kinase (4) Autophagy (11) Bacterial (31) Bcl-2 Family (1) Calcium Channel (6) Carbonic Anhydrase (2) Caspase (1) Cathepsin (1) CDK (3) CHIKV (5) Cholinesterase (ChE) (2) ClpP (1) CMV (3) COX (5) CXCR (1) Cyclin G-associated Kinase (GAK) (1) Dengue Virus (1) Dopamine Receptor (3) Drug Metabolite (2) E1/E2/E3 Enzyme (1) EBV (1) Endogenous Metabolite (12) Enterovirus (8) Epigenetic Reader Domain (1) ERK (3) FAAH (1) FAK (1) Ferroptosis (1) Fungal (18) GABA Receptor (2) Glucocorticoid Receptor (4) Glutathione S-transferase (1) HBV (3) HCV (2) HIF/HIF Prolyl-Hydroxylase (4) Histamine Receptor (2) HIV (12) HIV Protease (1) HPV (1) HSP (4) HSV (7) Indoleamine 2,3-Dioxygenase (IDO) (4) Influenza Virus (21) Integrin (4) Interleukin Related (7) Isotope-Labeled Compounds (9) JAK (3) JNK (5) Keap1-Nrf2 (4) Liposome (1) mAChR (4) MAGL (1) MDM-2/p53 (1) Microtubule/Tubulin (1) MMP (3) mTOR (2) NF-κB (18) NO Synthase (3) P-glycoprotein (2) p38 MAPK (5) Parasite (10) Phosphatase (2) Phosphodiesterase (PDE) (2) Phospholipase (1) PI3K (3) PKA (2) PPAR (1) Pyroptosis (2) RAR/RXR (4) Reactive Oxygen Species (ROS) (12) Reference Standards (30) ROS Kinase (2) RSV (2) S100 Protein (2) SARS-CoV (10) SOD (2) STAT (1) TNF Receptor (3) Topoisomerase (1) VEGFR (2) Virus Protease (10)
By Research Areas:	Cancer (72) Cardiovascular Disease (7) Endocrinology (4) Infection (92) Inflammation/Immunology (94) Metabolic Disease (20) Neurological Disease (29)

By Targets:

11β-HSD (1)

5-HT Receptor (2)

ADC Payload (2)

Adrenergic Receptor (1)

Akt (3)

Amyloid-β (6)

Antibiotic (10)

AP-1 (1)

Apoptosis (43)

ATP-binding cassette (ABC) transporters (1)

Aurora Kinase (4)

Autophagy (11)

Bacterial (31)

Bcl-2 Family (1)

Calcium Channel (6)

Carbonic Anhydrase (2)

Caspase (1)

Cathepsin (1)

CDK (3)

CHIKV (5)

Cholinesterase (ChE) (2)

ClpP (1)

CMV (3)

COX (5)

CXCR (1)

Cyclin G-associated Kinase (GAK) (1)

Dengue Virus (1)

Dopamine Receptor (3)

Drug Metabolite (2)

E1/E2/E3 Enzyme (1)

EBV (1)

Endogenous Metabolite (12)

Enterovirus (8)

Epigenetic Reader Domain (1)

ERK (3)

FAAH (1)

FAK (1)

Ferroptosis (1)

Fungal (18)

GABA Receptor (2)

Glucocorticoid Receptor (4)

Glutathione S-transferase (1)

HBV (3)

HCV (2)

HIF/HIF Prolyl-Hydroxylase (4)

Histamine Receptor (2)

HIV (12)

HIV Protease (1)

HPV (1)

HSP (4)

HSV (7)

Indoleamine 2,3-Dioxygenase (IDO) (4)

Influenza Virus (21)

Integrin (4)

Interleukin Related (7)

Isotope-Labeled Compounds (9)

JAK (3)

JNK (5)

Keap1-Nrf2 (4)

Liposome (1)

mAChR (4)

MAGL (1)

MDM-2/p53 (1)

Microtubule/Tubulin (1)

MMP (3)

mTOR (2)

NF-κB (18)

NO Synthase (3)

P-glycoprotein (2)

p38 MAPK (5)

Parasite (10)

Phosphatase (2)

Phosphodiesterase (PDE) (2)

Phospholipase (1)

PI3K (3)

PKA (2)

PPAR (1)

Pyroptosis (2)

RAR/RXR (4)

Reactive Oxygen Species (ROS) (12)

Reference Standards (30)

ROS Kinase (2)

RSV (2)

S100 Protein (2)

SARS-CoV (10)

SOD (2)

STAT (1)

TNF Receptor (3)

Topoisomerase (1)

VEGFR (2)

Virus Protease (10)

By Research Areas:

Cancer (72)

Cardiovascular Disease (7)

Endocrinology (4)

Infection (92)

Inflammation/Immunology (94)

Metabolic Disease (20)

Neurological Disease (29)

115

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Fat Mass and Obesity-associated Protein (FTO)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-150521

Hispolon	Antibiotic	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Hispolon, a polyphenol, can be isolated from Phellinus linteus. Hispolon possesses anticancer, antidiabetic, antioxidant, antiviral, hepatoprotective, anti-diabetic, and anti-inflammatory activities .

HY-N6829

Retusin Quercetin-3,3',4',7-tetramethylether	Antibiotic	Infection Inflammation/Immunology
Retusin (Quercetin-3,3',4',7-tetramethylether), a natural compound isolated from the leaves of Talinum triangulare, possesses antiviral and anti-inflammatory activities .

HY-118383

Agathisflavone	Parasite	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities. Agathisflavone can improve tissue repair in a spinal cord injury model in rats .

HY-125850

Berberrubine chloride 1 Publications Verification	Drug Metabolite HIV Interleukin Related	Infection Inflammation/Immunology Cancer
Berberrubine chloride is an orally active metabolite of berberine. Berberrubine chloride alleviates mucosal lesions and inflammation in mouse colitis models. Berberrubine chloride has anti-inflammatory, anti-tumor, and antiviral activities .

HY-N0452

Hyperoside 5+ Cited Publications Quercetin 3-O-galactoside; Quercetin 3-O-β-D-galactopyranoside	Influenza Virus Fungal NF-κB Apoptosis	Infection Inflammation/Immunology Cancer
Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis .

HY-N1451

Betulonic acid 4 Publications Verification Betunolic acid; Liquidambaric acid; (+)-Betulonic acid	Parasite HSV	Infection Inflammation/Immunology Cancer
Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities .

HY-B0154

Fluticasone (propionate) 1 Publications Verification	Glucocorticoid Receptor Enterovirus Endogenous Metabolite ADC Payload	Infection Inflammation/Immunology Endocrinology
Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (K_D) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity .

HY-N14780

Pochonin D (+)-Pochonin D	HSP Interleukin Related Enterovirus	Infection Inflammation/Immunology Cancer
Pochonin D ((+)-Pochonin D) is an inhibitor of heat shock protein 90 (Hsp90) with antiviral and anti-inflammatory activities. Pochonin D inhibits Hsp90, affecting the homeostasis, folding, and assembly processes of viral proteins, reducing the replication ability of the virus. Pochonin D reduces the infiltration of inflammatory cells and the secretion of inflammatory cytokines such as TNF-α and IL-1β, alleviating the inflammatory response. Pochonin D is promising for research of Human rhinoviruses (HRV) infections and cancers .

HY-N10672

Kuguacin R	Antibiotic	Infection Inflammation/Immunology
Kuguacin R is a cucurbitane-type triterpenoid that can be extracted from Momordica charantia L. Kuguacin R possess anti-inflammatory, antimicrobial and anti-viral activities .

HY-N3017R

Artemitin (Standard)	Antibiotic Reference Standards	Infection Inflammation/Immunology
Artemitin (Standard) is the analytical standard of Artemitin. This product is intended for research and analytical applications. Artemitin is a flavonol found in Laggera pterodonta (DC.) Benth., with antioxidative, anti-inflammatory, and antiviral activity .

HY-70072

D609 5+ Cited Publications	Phospholipase	Infection Inflammation/Immunology Cancer
D609, an antitumoural xanthate, is a specific and competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor with a K_i of 6.4 μM. D609 is an antioxidative protector and has antiviral and anti-inflammatory activity .

HY-N0055

Chlorogenic acid 15+ Cited Publications 3-O-Caffeoylquinic acid; Heriguard; NSC-407296	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Bacterial Influenza Virus Endogenous Metabolite	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .

HY-N0757

8-O-Acetylharpagide	Bacterial	Infection Inflammation/Immunology Cancer
8-O-Acetylharpagide is an iridoid isolated from Ajuga reptans with antitumoral, antiviral, antibacterial, and anti-inflammatory activities. 8-O-Acetylharpagide also has a biological activity on isolated smooth muscle preparations from guinea pig .

HY-N1745A

3-Deoxysappanchalcone 2 Publications Verification	Influenza Virus	Infection Inflammation/Immunology
3-Deoxysappanchalcone is a naturally-occurring chalcone compound found in Caesalpinia sappan L. (Leguminosae), which possesses anti-allergic, antiviral, anti-inflammatory and antioxidant activities. 3-Deoxysappanchalcone exerts anti-inflammatory activity via induce heme oxygenase-1 (HO-1) expression by activating the AKT/mTOR pathway in murine macrophages. 3-Deoxysappanchalcone also exhibits anti-influenza virus activity (H3N2, IC₅₀ = 1.06 μM) .

HY-W012634S

Benzothiazole-d4	Isotope-Labeled Compounds Bacterial	Cancer
Benzothiazole-d₄ is a deuterium labeled Benzothiazole (HY-W012634). Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral .

HY-N13197

6-Methyl-5,6-dihydro-2H-pyran-2-one	Antibiotic Bacterial Fungal Parasite	Infection Inflammation/Immunology Cancer
6-Methyl-5,6-dihydro-2H-pyran-2-one is a heterocyclic compound with antitumor, antifungal, antimicrobial, anti-inflammatory, antistress, antibiotic, antituberculosis, antiparasitic, antiviral activities .

HY-N0035

Arctigenin 5+ Cited Publications (-)-Arctigenin	MMP Influenza Virus Autophagy Apoptosis	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions .

HY-N6829R

Retusin (Standard) Quercetin-3,3',4',7-tetramethylether (Standard)	Antibiotic Reference Standards	Infection Inflammation/Immunology
Retusin (Standard) is the analytical standard of Retusin. This product is intended for research and analytical applications. Retusin (Quercetin-3,3',4',7-tetramethylether), a natural compound isolated from the leaves of Talinum triangulare, possesses antiviral and anti-inflammatory activities .

HY-N9104

ent-Labda-8(17),13Z-diene-15,16,19-triol 19-O-glucoside	Others	Inflammation/Immunology
ent-Labda-8(17),13Z-diene-15,16,19-triol 19-O-glucoside is a natural product derived from the leaves of Andrographis paniculata that has anti-inflammatory and antiviral activity .

HY-125850R

Berberrubine chloride (Standard)	Drug Metabolite Reference Standards HIV Interleukin Related	Infection Inflammation/Immunology Cancer
Berberrubine (chloride) (Standard) is the analytical standard of Berberrubine (chloride). This product is intended for research and analytical applications. Berberrubine chloride is an orally active metabolite of berberine. Berberrubine chloride alleviates mucosal lesions and inflammation in mouse colitis models. Berberrubine chloride has anti-inflammatory, anti-tumor, and antiviral activities .

HY-119283

CAY10499 1 Publications Verification MAGL-IN-5	MAGL FAAH SARS-CoV Influenza Virus	Infection Metabolic Disease Inflammation/Immunology
CAY10499 (MAGL-IN-5) is a non-selective lipase inhibitor with IC₅₀ values of 144 nM and 14 nM for monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH), respectively. Additionally, CAY10499 exhibits anti-inflammatory and antiviral activities .

HY-N6980

Licorice glycoside C2 1 Publications Verification	HIV	Infection Cancer
Licorice glycoside C2 is a oleanane-type triterpene oligoglycoside isolated from Glycyrrhiza uralensis. Various biological activities are associated with licorice extracts, such as anti-viral, anti-microbial, antioxidant, anti-inflammatory, anti-ulcer, anti-cancer and anti-HIV effects .

HY-W012634

Benzothiazole	Bacterial	Infection Metabolic Disease Inflammation/Immunology Cancer
Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent ^[1][2][3][4].

HY-B0154S1

Fluticasone propionate-d5	Isotope-Labeled Compounds Glucocorticoid Receptor Enterovirus Endogenous Metabolite	Infection Inflammation/Immunology Endocrinology
Fluticasone propionate-d₅ is deuterium labeled Fluticasone (propionate). Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity .

HY-B0154S

Fluticasone propionate-d3	Isotope-Labeled Compounds Glucocorticoid Receptor Enterovirus Endogenous Metabolite	Infection Inflammation/Immunology Endocrinology
Fluticasone propionate-d₃ is the deuterium labeled Fluticasone propionate. Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity .

HY-N9337

Amaroswerin	NO Synthase	Metabolic Disease Inflammation/Immunology Cancer
Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC₅₀ value of 5.42 μg/mL in RAW264.7 cells .

HY-143692

SQDG	Liposome HSV Topoisomerase MDM-2/p53 Apoptosis	Infection Inflammation/Immunology Cancer
SQDG inhibits topoisomerase I and P-selectin receptor, exhibits anti-inflammatory, antiviral and antitumor activities. SQDG is a glycolipid that possesses sugar moieties in their head groups. SQDG is a membrane lipid that can be used to investigate the effects of structural lipid in LNP formulations .

HY-W835723

1-(2,6-Dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one	Others	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology
1-(2,6-Dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one is a phenolic compound derived from Dracaena cochinchinensis that exhibits antioxidant, antimicrobial, antiviral, hemostatic, antithrombotic, anti-inflammatory activities, and protects myocardial cells .

HY-N0452R

Hyperoside (Standard) Quercetin 3-O-galactoside (Standard); Quercetin 3-O-β-D-galactopyranoside (Standard)	Reference Standards Influenza Virus Fungal NF-κB Apoptosis	Infection Inflammation/Immunology Cancer
Hyperoside (Standard) is the analytical standard of Hyperoside. This product is intended for research and analytical applications. Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis .

HY-N1451R

Betulonic acid (Standard) Betunolic acid (Standard); Liquidambaric acid (Standard); (+)-Betulonic acid (Standard)	Reference Standards Parasite HSV	Infection Inflammation/Immunology Cancer
Betulonic acid (Standard) is the analytical standard of Betulonic acid. This product is intended for research and analytical applications. Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities .

HY-P99490

Burfiralimab hzVSF-v13	Interleukin Related SARS-CoV	Infection Inflammation/Immunology
Burfiralimab (hzVSF-v13) is a monoclonal IgG4 antibody against vimentin expressed on the surface of virus-infected cells, with broad-spectrum antiviral activity and anti-inflammatory effects against virus-induced inflammation. Burfiralimab can be used in severe COVID-19 studies .

HY-N0328

alpha-Mangostin 5+ Cited Publications α-Mangostin	Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal Virus Protease	Cancer
alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a K_i of 2.85 μM.

HY-110398

5,6,7-Trimethoxyflavone Baicalein trimethyl ether	NF-κB AP-1 STAT HSV CMV Enterovirus	Infection Inflammation/Immunology
5,6,7-Trimethoxyflavone is a flavonoid compound that can be isolated from plants Callicarpa japonica. 5,6,7-Trimethoxyflavone exhibits antiviral and anti-inflammatory activities through inhibition of NF-κB/AP-1/STAT signaling pathway .

HY-128423A

Tylvalosin Acetylisovaleryltylosin	Antibiotic Bacterial NF-κB Apoptosis	Infection Inflammation/Immunology Cancer
Tylvalosin (Acetylisovaleryltylo?sin) is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin is an antiviral agent used to study PRRSV infection. Tylvalosin induces apoptosis. Tylvalosin also has anti-inflammatory activity, alleviates oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation .

HY-B0154R

Fluticasone (propionate) (Standard)	Reference Standards Glucocorticoid Receptor Enterovirus Endogenous Metabolite ADC Payload	Infection Inflammation/Immunology Endocrinology
Fluticasone (propionate) (Standard) is the analytical standard of Fluticasone (propionate). This product is intended for research and analytical applications. Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity .

HY-N0528

Linarin 1 Publications Verification Buddleoside; Linarine	TNF Receptor Cholinesterase (ChE) PKA Apoptosis Bacterial HIV Influenza Virus	Infection Neurological Disease Inflammation/Immunology Cancer
Linarin (Buddleoside) is an orally active and selective inhibitor of acetylcholinesterase (AChE). Linarin has many activities, such as anti-inflammatory, antioxidant, sleep aid and sedation, bone differentiation, anti-tumor, antibacterial and antiviral. Linarin can be used to study diseases such as the nervous system, osteoporosis and cancer .

HY-W131122

1,3,4-Oxadiazole	Bacterial	Others
1,3,4-Oxadiazoles are a class of synthetic compounds with important medicinal value, which show a variety of biological activities such as anticonvulsant, antidepressant, analgesic, anti-inflammatory, antiallergic, antipsychotic, antimicrobial, antituberculous, antitumor, and antiviral. 1,3,4-Oxadiazole derivatives need to be further developed .

HY-158995S

3-Epiglycyrrhetinic acid-d2 3α-Glycyrrhetic acid-d₂	Isotope-Labeled Compounds	Others
3-Epiglycyrrhetinic acid-d2 (3α-Glycyrrhetic acid-d2) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .

HY-158995S1

3-Epiglycyrrhetinic acid-d3 3α-Glycyrrhetic acid-d₃	Isotope-Labeled Compounds	Others
3-Epiglycyrrhetinic acid-d3 (3α-Glycyrrhetic acid-d3) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .

HY-14904A

Umifenovir hydrochloride 5+ Cited Publications	Influenza Virus SARS-CoV CHIKV	Infection
Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells . Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity .

HY-N0055R

Chlorogenic acid (Standard) 3-O-Caffeoylquinic acid (Standard); Heriguard (Standard); NSC-407296 (Standard)	Reference Standards HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Bacterial Influenza Virus Endogenous Metabolite	Infection Inflammation/Immunology Cancer
Chlorogenic acid (Standard) is the analytical standard of Chlorogenic acid. This product is intended for research and analytical applications. Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .

HY-N0416

Cucurbitacin B 5+ Cited Publications	HIF/HIF Prolyl-Hydroxylase Integrin Autophagy Apoptosis Endogenous Metabolite ROS Kinase COX	Others Neurological Disease Inflammation/Immunology Cancer
Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity .

HY-N2590

Lupenone	Parasite PI3K Akt mTOR NF-κB	Infection Inflammation/Immunology Cancer
Lupenone is an orally active lupine-type triterpenoid that can be isolated from Musa basjoo. Lupenone Lupenone plays a role through the PI3K/Akt/mTOR and NF-κB signaling pathways. Lupenone has anti-inflammatory, *antiviral, antidiabetic and anticancer activities* .

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal RSV GABA Receptor	Infection Neurological Disease Inflammation/Immunology Cancer
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N1535

Ponicidin 3 Publications Verification Rubescensine B	Apoptosis	Inflammation/Immunology Cancer
Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens, and exhibits immunoregulatory, anti-inflammatory, anti-viral and anti-cancer activity. Ponicidin (Rubescensine B) induces apoptosis of gastric carcinoma cell, decreases the phosphorylation of JAK2 and STAT3, and shows no effect on protein levels of JAK2 and STAT3 .

HY-N10335

Harringtonolide 1 Publications Verification	FAK	Inflammation/Immunology Cancer
Harringtonolide is a potent RACK1 inhibitor (IC₅₀=39.66 μM in A375 cells). Harringtonolide inhibits the epithelial-mesenchymal transition (EMT) process and cell proliferation by affecting the interaction between FAK and RACK1. Harringtonolide has plant growth inhibitory, antiviral, anti-inflammatory, and antiproliferation activities .

HY-128423

Tylvalosin tartrate Acetylisovaleryltylosin tartrate	Antibiotic Bacterial NF-κB Apoptosis	Infection Inflammation/Immunology
Tylvalosin (Acetylisovaleryltylosin) tartrate is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin tartrate is an antiviral agent useful in studying PRRSV infection. Tylvalosin tartrate induces apoptosis. Tylvalosin tartrate also has anti-inflammatory activity, relieves oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation .

HY-D0803

Thymoquinone 5+ Cited Publications	Apoptosis VEGFR PI3K Akt	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Thymoquinone is an orally active natural product isolated from N. sativa Thymoquinone down-regulates the VEGFR2-PI3K-Akt pathway. Thymoquinone has antioxidant, anti-inflammatory, anticancer, antiviral, anticonvulsant, antifungal, antiviral, antiangiogenic activity and hepatoprotective effects. Thymoquinone can be used to study Alzheimer's disease, cancer, cardiovascular disease, infectious disease and inflammation .

HY-W012634R

Benzothiazole (Standard)	Reference Standards Bacterial	Infection Metabolic Disease Inflammation/Immunology Cancer
Benzothiazole (Standard) is the analytical standard of Benzothiazole. This product is intended for research and analytical applications. Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent .

HY-N0035R

Arctigenin (Standard) (-)-Arctigenin (Standard)	Reference Standards MMP Influenza Virus Autophagy Apoptosis	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Arctigenin (Standard) is the analytical standard of Arctigenin. This product is intended for research and analytical applications. Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions .

Cat. No.	Product Name	Type

HY-143692

SQDG	Drug Delivery
SQDG inhibits topoisomerase I and P-selectin receptor, exhibits anti-inflammatory, antiviral and antitumor activities. SQDG is a glycolipid that possesses sugar moieties in their head groups. SQDG is a membrane lipid that can be used to investigate the effects of structural lipid in LNP formulations .

HY-P3161

Lactoferrin from Bovine milk

Native Proteins

Lactoferrin from Bovine milk is a substance released by neutrophils. Lactoferrin from Bovine milk is an orally active multifunctional iron binding glycoprotein. Lactoferrin from Bovine milk prevents cell adhesion, growth and spreading of cell colonies. Lactoferrin from Bovine milk also has antiviral activity and inhibits microbial and viral adhesion and entry into host cells. Besides, Lactoferrin from Bovine milk has anti-inflammatory, immunomodulatory, and anti-cancer activities .

Cat. No.	Product Name	Target	Research Area

HY-P5581

Alloferon 1	Peptides	Infection Inflammation/Immunology Cancer
Alloferon 1 is an antiviral and antitumoral peptide. Alloferon 1 stimulates natural cytotoxicity of human peripheral blood lymphocytes. Alloferon 1 also induces IFN synthesis, and enhances antiviral and antitumor resistance in mice. Alloferon 1 also shows anti-inflammatory activity in λ-carrageenan-induced paw edema model. Alloferon 1 can be isolated from the blood of the blow fly Calliphora vicina (Diptera) .

HY-P10415

EPI-X4 1 Publications Verification hSA(408–423) peptide	CXCR	Infection Inflammation/Immunology Cancer
EPI-X4 (hSA408–423 peptide) is an antagonist for C-X-C motif chemokine receptor 4 (CXCR4) with IC₅₀ of 8.6 μM. EPI-X4 blocks the CXCL12-mediated signaling, inhibits chemokine-mediated migration and invasion of leukemia cell. EPI-X4 exhibits anti-inflammatory activity in mouse model. EPI-X4 exhibits antiviral activity against CXCR4-tropic HIV with IC₅₀ of 8.6 μM .

HY-P10056

HEP-1 Human ezrin peptide (324-337)	HIV HCV HPV Influenza Virus Interleukin Related	Infection Inflammation/Immunology
HEP-1 (Human ezrin peptide (324 - 337)) is an orally active peptide with antiviral, anti-inflammatory, and immunomodulatory activities. HEP-1 is effective against infections by various viruses such as HIV, HCV, herpes viruses, HPV, and influenza viruses. As an immunomodulator, HEP-1 can enhance the adaptive immunity mediated by B cells and T cells. HEP-1 can also increase the antibody titers after hepatitis B vaccination. HEP-1 can be used in the research of viral infections and inflammation-related diseases .

HY-P1633

Protegrin-1 PG1	Bacterial ERK COX NF-κB Apoptosis NO Synthase Dengue Virus	Infection Inflammation/Immunology
Protegrin-1 is an orally active antibacterial peptide. Protegrin-1 activates ERK, COX2, NFκB, inhibits Apoptosis, and NO production. Protegrin-1 has antibacterial activity against S. aureus, E. faecium, E. coli, P. aeruginosa and K. Pneumoniae, with MBC values between 10 and 20 µM. Protegrin-1 has *antiviral* activity against dengue NS2B-NS3. Protegrin-1 has anti-inflammatory activity. Protegrin-1 is used in the study of inflammatory diseases and infections .

Cat. No.	Product Name	Target	Research Area

HY-P99490

Burfiralimab hzVSF-v13	Interleukin Related SARS-CoV	Infection Inflammation/Immunology
Burfiralimab (hzVSF-v13) is a monoclonal IgG4 antibody against vimentin expressed on the surface of virus-infected cells, with broad-spectrum antiviral activity and anti-inflammatory effects against virus-induced inflammation. Burfiralimab can be used in severe COVID-19 studies .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-150521

Hispolon	Infection Structural Classification Microorganisms Classification of Application Fields Phenols Polyphenols Metabolic Disease Disease Research Fields Cancer	Antibiotic
Hispolon, a polyphenol, can be isolated from Phellinus linteus. Hispolon possesses anticancer, antidiabetic, antioxidant, antiviral, hepatoprotective, anti-diabetic, and anti-inflammatory activities .

HY-N6829

Retusin Quercetin-3,3',4',7-tetramethylether	Flavonols Structural Classification Monophenols Flavonoids Classification of Application Fields Entada phaseoloides (L.) Merr. Labiatae Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	Antibiotic
Retusin (Quercetin-3,3',4',7-tetramethylether), a natural compound isolated from the leaves of Talinum triangulare, possesses antiviral and anti-inflammatory activities .

HY-118383

Agathisflavone	Structural Classification Flavonoids Flavones Source classification Araucariaceae Agathis robusta (C. Moore ex F. Muell.) F. M. Bailey Plants	Parasite
Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities. Agathisflavone can improve tissue repair in a spinal cord injury model in rats .

HY-125850

Berberrubine chloride 1 Publications Verification	Alkaloids Structural Classification Phellodendron amurense Rupr. Monophenols Classification of Application Fields Source classification Rutaceae Phenols Plants Isoquinoline Alkaloids Inflammation/Immunology Disease Research Fields	Drug Metabolite HIV Interleukin Related
Berberrubine chloride is an orally active metabolite of berberine. Berberrubine chloride alleviates mucosal lesions and inflammation in mouse colitis models. Berberrubine chloride has anti-inflammatory, anti-tumor, and antiviral activities .

HY-N0452

Hyperoside 5+ Cited Publications Quercetin 3-O-galactoside; Quercetin 3-O-β-D-galactopyranoside	Flavonols Structural Classification Flavonoids Classification of Application Fields Guttiferae Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Hypericum monogynum L.	Influenza Virus Fungal NF-κB Apoptosis
Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis .

HY-N1451

Betulonic acid 4 Publications Verification Betunolic acid; Liquidambaric acid; (+)-Betulonic acid	Infection Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields	Parasite HSV
Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities .

HY-N0055

Chlorogenic acid Maximum Cited Publications 18 Publications Verification 3-O-Caffeoylquinic acid; Heriguard; NSC-407296	Structural Classification Caprifoliaceae Classification of Application Fields Lonicera japonica Thunb. Anti-aging Source classification Plants Endogenous metabolite Infection Human Gut Microbiota Metabolites Microorganisms Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Inflammation/Immunology Disease Research Fields Cancer	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Bacterial Influenza Virus Endogenous Metabolite
Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .

HY-N14780

Pochonin D (+)-Pochonin D	Structural Classification Natural Products Microorganisms Source classification	HSP Interleukin Related Enterovirus
Pochonin D ((+)-Pochonin D) is an inhibitor of heat shock protein 90 (Hsp90) with antiviral and anti-inflammatory activities. Pochonin D inhibits Hsp90, affecting the homeostasis, folding, and assembly processes of viral proteins, reducing the replication ability of the virus. Pochonin D reduces the infiltration of inflammatory cells and the secretion of inflammatory cytokines such as TNF-α and IL-1β, alleviating the inflammatory response. Pochonin D is promising for research of Human rhinoviruses (HRV) infections and cancers .

HY-N10672

Kuguacin R	Triterpenes Source classification Cucurbitaceae Plants Momordica charantia Linn.	Antibiotic
Kuguacin R is a cucurbitane-type triterpenoid that can be extracted from Momordica charantia L. Kuguacin R possess anti-inflammatory, antimicrobial and anti-viral activities .

HY-N3017R

Artemitin (Standard)	Flavonols Structural Classification Monophenols Flavonoids other families Source classification Phenols Plants	Antibiotic Reference Standards
Artemitin (Standard) is the analytical standard of Artemitin. This product is intended for research and analytical applications. Artemitin is a flavonol found in Laggera pterodonta (DC.) Benth., with antioxidative, anti-inflammatory, and antiviral activity .

HY-N0757

8-O-Acetylharpagide	Infection Structural Classification other families Iridoids Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields	Bacterial
8-O-Acetylharpagide is an iridoid isolated from Ajuga reptans with antitumoral, antiviral, antibacterial, and anti-inflammatory activities. 8-O-Acetylharpagide also has a biological activity on isolated smooth muscle preparations from guinea pig .

HY-N1745A

3-Deoxysappanchalcone 2 Publications Verification	Structural Classification Chalcones Flavonoids Classification of Application Fields Leguminosae Caesalpinia sappan L. Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	Influenza Virus
3-Deoxysappanchalcone is a naturally-occurring chalcone compound found in Caesalpinia sappan L. (Leguminosae), which possesses anti-allergic, antiviral, anti-inflammatory and antioxidant activities. 3-Deoxysappanchalcone exerts anti-inflammatory activity via induce heme oxygenase-1 (HO-1) expression by activating the AKT/mTOR pathway in murine macrophages. 3-Deoxysappanchalcone also exhibits anti-influenza virus activity (H3N2, IC₅₀ = 1.06 μM) .

HY-N13197

6-Methyl-5,6-dihydro-2H-pyran-2-one	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial Fungal Parasite
6-Methyl-5,6-dihydro-2H-pyran-2-one is a heterocyclic compound with antitumor, antifungal, antimicrobial, anti-inflammatory, antistress, antibiotic, antituberculosis, antiparasitic, antiviral activities .

HY-N0035

Arctigenin 5+ Cited Publications (-)-Arctigenin	Structural Classification Neurological Disease Classification of Application Fields Anti-aging Source classification Lignans Metabolic Disease Plants Compositae Caesalpinia magnifoliolata Metc. Endogenous metabolite Infection Human Gut Microbiota Metabolites Phenylpropanoids Inflammation/Immunology Disease Research Fields Cancer	MMP Influenza Virus Autophagy Apoptosis
Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions .

HY-N6829R

Retusin (Standard) Quercetin-3,3',4',7-tetramethylether (Standard)	Flavonols Structural Classification Monophenols Flavonoids Entada phaseoloides (L.) Merr. Labiatae Source classification Phenols Plants	Antibiotic Reference Standards
Retusin (Standard) is the analytical standard of Retusin. This product is intended for research and analytical applications. Retusin (Quercetin-3,3',4',7-tetramethylether), a natural compound isolated from the leaves of Talinum triangulare, possesses antiviral and anti-inflammatory activities .

HY-N9104

ent-Labda-8(17),13Z-diene-15,16,19-triol 19-O-glucoside	Structural Classification Natural Products Andrographis paniculata (Burm. F.) Nees Acanthaceae Source classification Plants	Others
ent-Labda-8(17),13Z-diene-15,16,19-triol 19-O-glucoside is a natural product derived from the leaves of Andrographis paniculata that has anti-inflammatory and antiviral activity .

HY-125850R

Berberrubine chloride (Standard)	Alkaloids Structural Classification Phellodendron amurense Rupr. Monophenols Source classification Rutaceae Phenols Plants Isoquinoline Alkaloids	Drug Metabolite Reference Standards HIV Interleukin Related
Berberrubine (chloride) (Standard) is the analytical standard of Berberrubine (chloride). This product is intended for research and analytical applications. Berberrubine chloride is an orally active metabolite of berberine. Berberrubine chloride alleviates mucosal lesions and inflammation in mouse colitis models. Berberrubine chloride has anti-inflammatory, anti-tumor, and antiviral activities .

HY-N6980

Licorice glycoside C2 1 Publications Verification	Infection Structural Classification Flavonoids Classification of Application Fields Leguminosae Flavonones Source classification Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch.	HIV
Licorice glycoside C2 is a oleanane-type triterpene oligoglycoside isolated from Glycyrrhiza uralensis. Various biological activities are associated with licorice extracts, such as anti-viral, anti-microbial, antioxidant, anti-inflammatory, anti-ulcer, anti-cancer and anti-HIV effects .

HY-W012634

Benzothiazole	Microorganisms Source classification	Bacterial
Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent ^[1][2][3][4].

HY-N9337

Amaroswerin	Iridoids Classification of Application Fields Terpenoids Source classification Gentianaceae Phenols Polyphenols Metabolic Disease Swertia mussotii Franch. Plants Disease Research Fields Inflammation/Immunology	NO Synthase
Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC₅₀ value of 5.42 μg/mL in RAW264.7 cells .

HY-W835723

1-(2,6-Dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one	Structural Classification Monophenols Source classification Phenols Plants Asparagaceae Juss.	Others
1-(2,6-Dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one is a phenolic compound derived from Dracaena cochinchinensis that exhibits antioxidant, antimicrobial, antiviral, hemostatic, antithrombotic, anti-inflammatory activities, and protects myocardial cells .

HY-N0452R

Hyperoside (Standard) Quercetin 3-O-galactoside (Standard); Quercetin 3-O-β-D-galactopyranoside (Standard)	Flavonols Structural Classification Flavonoids Guttiferae Source classification Phenols Polyphenols Plants Hypericum monogynum L.	Reference Standards Influenza Virus Fungal NF-κB Apoptosis
Hyperoside (Standard) is the analytical standard of Hyperoside. This product is intended for research and analytical applications. Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis .

HY-N1451R

Betulonic acid (Standard) Betunolic acid (Standard); Liquidambaric acid (Standard); (+)-Betulonic acid (Standard)	Triterpenes Structural Classification other families Terpenoids Source classification Plants	Reference Standards Parasite HSV
Betulonic acid (Standard) is the analytical standard of Betulonic acid. This product is intended for research and analytical applications. Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities .

HY-N0328

alpha-Mangostin 5+ Cited Publications α-Mangostin	Structural Classification other families Xanthones Classification of Application Fields Phenols Polyphenols Plants Disease Research Fields Cancer	Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal Virus Protease
alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a K_i of 2.85 μM.

HY-110398

5,6,7-Trimethoxyflavone Baicalein trimethyl ether	Structural Classification Flavonoids Classification of Application Fields Flavones Verbenaceae Bignoniaceae Plants Oroxylum indicum (Linn.) Bentham ex Kurz Callicarpa japonica Thunb. Inflammation/Immunology Disease Research Fields Cancer	NF-κB AP-1 STAT HSV CMV Enterovirus
5,6,7-Trimethoxyflavone is a flavonoid compound that can be isolated from plants Callicarpa japonica. 5,6,7-Trimethoxyflavone exhibits antiviral and anti-inflammatory activities through inhibition of NF-κB/AP-1/STAT signaling pathway .

HY-B0154R

Fluticasone (propionate) (Standard)	Structural Classification Source classification Steroids	Reference Standards Glucocorticoid Receptor Enterovirus Endogenous Metabolite ADC Payload
Fluticasone (propionate) (Standard) is the analytical standard of Fluticasone (propionate). This product is intended for research and analytical applications. Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity .

HY-N0528

Linarin 1 Publications Verification Buddleoside; Linarine	Structural Classification Flavonoids Flavones Labiatae Source classification Erythrina poeppigiana Plants	TNF Receptor Cholinesterase (ChE) PKA Apoptosis Bacterial HIV Influenza Virus
Linarin (Buddleoside) is an orally active and selective inhibitor of acetylcholinesterase (AChE). Linarin has many activities, such as anti-inflammatory, antioxidant, sleep aid and sedation, bone differentiation, anti-tumor, antibacterial and antiviral. Linarin can be used to study diseases such as the nervous system, osteoporosis and cancer .

HY-N0055R

Chlorogenic acid (Standard) 3-O-Caffeoylquinic acid (Standard); Heriguard (Standard); NSC-407296 (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Caprifoliaceae Simple Phenylpropanols Lonicera japonica Thunb. Source classification Phenols Polyphenols Phenylpropanoids Plants Endogenous metabolite	Reference Standards HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Bacterial Influenza Virus Endogenous Metabolite
Chlorogenic acid (Standard) is the analytical standard of Chlorogenic acid. This product is intended for research and analytical applications. Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .

HY-N0416

Cucurbitacin B 5+ Cited Publications	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Cucurbitaceae Trichosanthes cucumerina L. Plants Endogenous metabolite Disease Research Fields Cancer	HIF/HIF Prolyl-Hydroxylase Integrin Autophagy Apoptosis Endogenous Metabolite ROS Kinase COX
Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity .

HY-N2590

Lupenone	Triterpenes Structural Classification Classification of Application Fields Source classification Musaceae Plants Compositae Infection Terpenoids Astragalus oleifolius DC. Musa basjoo Sieb. et Zucc. Inflammation/Immunology Disease Research Fields Cancer	Parasite PI3K Akt mTOR NF-κB
Lupenone is an orally active lupine-type triterpenoid that can be isolated from Musa basjoo. Lupenone Lupenone plays a role through the PI3K/Akt/mTOR and NF-κB signaling pathways. Lupenone has anti-inflammatory, *antiviral, antidiabetic and anticancer activities* .

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N1535

Ponicidin 3 Publications Verification Rubescensine B	Structural Classification other families Classification of Application Fields Terpenoids Labiatae Source classification Diterpenoids Emilia sonchifolia (L.) DC. Plants Inflammation/Immunology Disease Research Fields	Apoptosis
Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens, and exhibits immunoregulatory, anti-inflammatory, anti-viral and anti-cancer activity. Ponicidin (Rubescensine B) induces apoptosis of gastric carcinoma cell, decreases the phosphorylation of JAK2 and STAT3, and shows no effect on protein levels of JAK2 and STAT3 .

HY-N10335

Harringtonolide 1 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Cephalotaxus harringtonia Plants Cephalotaxaceae Inflammation/Immunology Disease Research Fields Cancer	FAK
Harringtonolide is a potent RACK1 inhibitor (IC₅₀=39.66 μM in A375 cells). Harringtonolide inhibits the epithelial-mesenchymal transition (EMT) process and cell proliferation by affecting the interaction between FAK and RACK1. Harringtonolide has plant growth inhibitory, antiviral, anti-inflammatory, and antiproliferation activities .

HY-D0803

Thymoquinone 5+ Cited Publications	Quinones Structural Classification Classification of Application Fields Nigella sativa L. Ranunculaceae Benzene Quinones Plants Inflammation/Immunology Disease Research Fields	Apoptosis VEGFR PI3K Akt
Thymoquinone is an orally active natural product isolated from N. sativa Thymoquinone down-regulates the VEGFR2-PI3K-Akt pathway. Thymoquinone has antioxidant, anti-inflammatory, anticancer, antiviral, anticonvulsant, antifungal, antiviral, antiangiogenic activity and hepatoprotective effects. Thymoquinone can be used to study Alzheimer's disease, cancer, cardiovascular disease, infectious disease and inflammation .

HY-W012634R

Benzothiazole (Standard)	Microorganisms Source classification	Reference Standards Bacterial
Benzothiazole (Standard) is the analytical standard of Benzothiazole. This product is intended for research and analytical applications. Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent .

HY-N0035R

Arctigenin (Standard) (-)-Arctigenin (Standard)	Structural Classification Human Gut Microbiota Metabolites Source classification Lignans Phenylpropanoids Plants Compositae Caesalpinia magnifoliolata Metc. Endogenous metabolite	Reference Standards MMP Influenza Virus Autophagy Apoptosis
Arctigenin (Standard) is the analytical standard of Arctigenin. This product is intended for research and analytical applications. Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral (influenza A virus) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions .

HY-N0528R

Linarin (Standard) Buddleoside (Standard); Linarine (Standard)	Structural Classification Flavonoids Flavones Labiatae Source classification Erythrina poeppigiana Plants	TNF Receptor Reference Standards Cholinesterase (ChE) PKA Apoptosis Bacterial HIV Influenza Virus
Linarin (Standard) is the analytical standard of Linarin. This product is intended for research and analytical applications. Linarin (Buddleoside) is an orally active and selective inhibitor of acetylcholinesterase (AChE). Linarin has many activities, such as anti-inflammatory, antioxidant, sleep aid and sedation, bone differentiation, anti-tumor, antibacterial and antiviral. Linarin can be used to study diseases such as the nervous system, osteoporosis and cancer.

HY-N0763R

Angelicin (Standard) Isopsoralen (Standard)	Structural Classification Leguminosae Source classification Coumarins Phenylpropanoids Psoralea corylifolia L. Plants	Reference Standards Apoptosis Virus Protease
Angelicin (Standard) is the analytical standard of Angelicin. This product is intended for research and analytical applications. Angelicin is a natural tricyclic aromatic hydrocarbon compound that is structurally related to psoralen and has anti-cancer, anti-inflammatory, anti-viral and other activities. Cytotoxic, IC₅₀: 49.56 μM; inhibits MHV-68, IC₅₀: 5.39 μg/ml (28.95 μM).

HY-133108

Azadirachtin B	Infection Structural Classification Natural Products other families Classification of Application Fields Source classification Metabolic Disease Plants Inflammation/Immunology Disease Research Fields Biological Pesticide Research Agricultural Research	EBV Parasite Phosphatase Influenza Virus
Azadirachtin B is an limonoid isolated from seed kernels of Azadirachta indica. Azadirachtin B increases alkaline phosphatase (ALP) activity and stimulates osteoblast differentiation. Azadirachtin B is active against the Epstein-Barr virus early antigen (EBV-EA). Azadirachtin B has insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral and osteogenic properties .

HY-107577

Gedunin	Infection Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields	HSP
Gedunin is a limonoid with anti-cancer, anti-viral, anti-inflammatory and insecticidal activities. Gedunin acts as a potent Hsp90 inhibitor and induces the degradation of Hsp90-dependent client proteins. Geduni may obstructs the entry of SARS-CoV-2 virus into human host cells and can be used for COVID-19 research .

HY-19827

Aeroplysinin 1 (+)-Aeroplysinin-1	Structural Classification Anti-inflammation/Immunoregulatory Classification of Application Fields Source classification Marine natural products Antibacterial Disease Research Other Antibiotics Infection Animals Antibiotics Antiviral Sponge Anticancer Disease Research Fields	Bacterial HIV Apoptosis
Aeroplysinin 1 ((+)-Aeroplysinin-1), a secondary metabolite isolated from marine sponges, shows potent antibiotic effects on Gram-positive bacteria and exerts antiviral activity against HIV-1 (IC₅₀=14.6 μM). Aeroplysinin 1 has anti-inflammatory, anti-angiogenic and anti-tumor activities. Aeroplysinin 1 induces apoptosis in endothelial cells .

HY-N0757R

8-?O-?Acetylharpagide (Standard)	Structural Classification other families Iridoids Terpenoids Source classification Plants	Reference Standards Bacterial
8-O-Acetylharpagide (Standard) is the analytical standard of 8-O-Acetylharpagide. This product is intended for research and analytical applications. 8-O-Acetylharpagide is an iridoid isolated from Ajuga reptans with antitumoral, antiviral, antibacterial, and anti-inflammatory activities. 8-O-Acetylharpagide also has a biological activity on isolated smooth muscle preparations from guinea pig .

HY-N2584A

Isoxanthohumol 2 Publications Verification	Infection Flavonoids Classification of Application Fields Anti-aging Humulus lupulus L. Flavonones Source classification Plants Moraceae Disease Research Fields Cancer	HSV Apoptosis Reactive Oxygen Species (ROS) Autophagy CMV Fungal Integrin S100 Protein
Isoxanthohumol is an orally active flavonoid compound. Isoxanthohumol has biological activities such as anti-tumor, anti-inflammatory, antioxidant, antiviral, antifungal, and inhibition of adipogenesis. Isoxanthohumol can induce apoptosis, autophagy, and migration of tumor cells. Isoxanthohumol is active against viruses such as HSV, BVDV, CMV, and Rhino. Isoxanthohumol can be used for the research of tumors, metabolic, and inflammatory diseases .

HY-N0639

Punicalin	Structural Classification Punica granatum L. Classification of Application Fields Source classification Phenols Polyphenols Punicaceae Plants Inflammation/Immunology Disease Research Fields	HBV Pyroptosis Carbonic Anhydrase
Punicalin is a species that can be isolated from the leaves of Punica granatum. Punicalin is an active molecule against hepatitis b virus (HBV). Punicalin can induce pyroptosis. Punicalin is a Carbonic anhydrase inhibitor. Punicalin blocks the binding of S-glycoprotein and ACE2 receptors. Pnuicalin has anti-inflammatory, antioxidant and antiviral activity .

HY-N2925

β-Amyrone β-Amyron	Triterpenes Structural Classification Caprifoliaceae Source classification Plants Sambucus adnata Wall. ex DC.	Fungal COX PPAR
β-Amyrone (β-Amyron) is a triterpene compound which has anti-inflammatory activity through inhibiting the expression of COX-2. β-Amyrone has antifungal activity , as well as antiviral activity against Chikungunya virus. β-Amyrone also inhibits α-glucosidase and acetylcholinesterase (AChE) activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity .

HY-D0803R

Thymoquinone (Standard)	Quinones Structural Classification Nigella sativa L. Ranunculaceae Benzene Quinones Plants	Reference Standards Apoptosis VEGFR PI3K Akt
Thymoquinone (Standard) is the analytical standard of Thymoquinone. This product is intended for research and analytical applications. Thymoquinone is an orally active natural product isolated from N. sativa Thymoquinone down-regulates the VEGFR2-PI3K-Akt pathway. Thymoquinone has antioxidant, anti-inflammatory, anticancer, antiviral, anticonvulsant, antifungal, antiviral, antiangiogenic activity and hepatoprotective effects. Thymoquinone can be used to study Alzheimer's disease, cancer, cardiovascular disease, infectious disease and inflammation .

HY-N9448

Lacto-N-tetraose	Infection Structural Classification Natural Products Human Gut Microbiota Metabolites Polysaccharides Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Saccharides	Bacterial
Lacto-N-tetraose is the significant core structure of human milk oligosaccharides (HMOs) naturally existing in human milk. Lacto-N-tetraose is consist of galactose, N-acetylglucosamine, and glucose moieties. Lacto-N-tetraose has prebiotic effect, immune regulatory effect, anti-inflammatory effects, intestinal cell responses regulatory effect, antibacterial activity and antiviral activity. Lacto-N-tetraose has been widely added to infant formula .

HY-N0328R

alpha-Mangostin (Standard) 5+ Cited Publications α-Mangostin (Standard)	Structural Classification other families Xanthones Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	Fungal Reactive Oxygen Species (ROS) Bacterial Apoptosis Virus Protease Reference Standards
alpha-Mangostin (Standard) is the analytical standard of alpha-Mangostin. This product is intended for research and analytical applications. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a K_i of 2.85 μM.

HY-N0662R

Amentoflavone (Standard) Didemethyl-ginkgetin (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reference Standards Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-135646

Eleutheroside B1	Structural Classification other families Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Influenza Virus
Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC₅₀ value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities .

Cat. No.	Product Name	Chemical Structure

HY-W012634S

Benzothiazole-d4
Benzothiazole-d₄ is a deuterium labeled Benzothiazole (HY-W012634). Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral .

HY-B0154S1

Fluticasone propionate-d5
Fluticasone propionate-d₅ is deuterium labeled Fluticasone (propionate). Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity .

HY-158995S

3-Epiglycyrrhetinic acid-d2
3-Epiglycyrrhetinic acid-d2 (3α-Glycyrrhetic acid-d2) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .

HY-158995S1

3-Epiglycyrrhetinic acid-d3
3-Epiglycyrrhetinic acid-d3 (3α-Glycyrrhetic acid-d3) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .

HY-14904AS

Umifenovir-d6 hydrochloride

Umifenovir-d₆ (hydrochloride) is the deuterium labeled Umifenovir hydrochloride. Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells . Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity .

HY-B0154S

Fluticasone propionate-d3
Fluticasone propionate-d₃ is the deuterium labeled Fluticasone propionate. Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity .

HY-N0055S

Chlorogenic acid-13C3

Chlorogenic acid- ¹³C₃ (Heriguard- ¹³C₃; NSC-407296- ¹³C₃) is ¹³C- and ¹⁵N-labeled Chlorogenic acid (HY-N0055). Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb.. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension .

HY-B1588S

Carbenoxolone-d4

Carbenoxolone-d₄ is deuterium labeled Carbenoxolone. Carbenoxolone, a semi-synthetic derivative of glycyrrhetinic acid, has previously been used for the management of dyspepsia and peptic ulcer because of its anti-inflammatory properties . Carbenoxolone, a general hemichannel and gap junction inhibitor, has the therapeutic potential of carbenoxolone in the research of chronic liver disease . Carbenoxolone is a suitable candidate for the inhibition of Aβ42 aggregation and the therapeutic potential of Cbx against AD . Carbenoxolone is small molecule Pannexin1 (Panx1,is an ATP release channel) inhibitor, attenuate Panx1 channel activity through modulation of the first extracellular loop .Carbenoxolone is an 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor that converts inactive glucocorticoid into an active form. Carbenoxolone has antiviral activity against DENV infection targeting the virus itself .

HY-W014589S

2,4-Di-tert-butylphenol-d19

2,4-Di-tert-butylphenol-d₁₉ (2,4-DTBP-d₁₉) is the deuterium labeled 2,4-Di-tert-butylphenol (HY-W014589). 2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of drugs and fragrances .

HY-W749327

2,4-Di-tert-butylphenol-d21

2,4-Di-tert-butylphenol-d₂1 (2,4-DTBP-d₂1) is the deuterium labeled 2,4-Di-tert-butylphenol (HY-W014589). 2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of drugs and fragrances .

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