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Results for "

G4

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) Apoptosis (12) Autophagy (2) Bcl-2 Family (2) Biochemical Assay Reagents (21) c-Myc (9) Caspase (1) CD3 (2) CD47 (1) Complement System (2) DAGL (1) DNA/RNA Synthesis (7) Endothelin Receptor (1) Eukaryotic Initiation Factor (eIF) (4) FATP (1) Ferroptosis (2) Fluorescent Dye (1) G-quadruplex (24) Glutathione Peroxidase (1) HDAC (1) HIV (1) Integrin (1) Interleukin Related (2) MAGL (1) Natriuretic Peptide Receptor (NPR) (1) NTPDase (1) PD-1/PD-L1 (3) PERK (1) Photosensitizer (1) PROTACs (1) Ras (1) Reactive Oxygen Species (ROS) (2) RGS Protein (3) Ser/Thr Protease (2) Small Interfering RNA (siRNA) (11) STING (1) Telomerase (4) Tie (1) TNF Receptor (2) Topoisomerase (1) Transmembrane Glycoprotein (1) Virus Protease (1)
By Research Areas:	Cancer (50) Cardiovascular Disease (1) Endocrinology (1) Infection (1) Inflammation/Immunology (18) Metabolic Disease (3) Neurological Disease (9)
Oligonucleotides:	Rat Pre-designed siRNA Sets (2) Mouse Pre-designed siRNA Sets (2) Human Pre-designed siRNA Sets (7) siRNAs (11)

107

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-170643

G4/hTERT-IN-4	G-quadruplex	Cancer
G4/hTERT-IN-4 (compound b4) is a potent inhibitor of *G4/hTERT*. G4/hTERT-IN-4 plays an important role in cancer research .

HY-P6022

G4RGDSP, integrin-binding peptide	Integrin	Others
G4RGDSP, Integrin-binding peptide is a cell integrin-binding peptide that targets integrin receptors. G4RGDSP, integrin-binding peptide is coupled to alginate to increase the viability of cells in the scaffold. G4RGDSP, integrin-binding peptide can be used as an extrudable carrier for chondrocyte delivery for the study of 3D printing technology

HY-P1771A

OVA G4 peptide TFA	Biochemical Assay Reagents	Inflammation/Immunology
OVA G4 peptide TFA is a variant of the agonist ovalbumin (OVA) peptide SIINFEKL (257-264). SIINFEKL is routinely used to stimulate ovalbumin-specific T cells and to test new vaccine adjuvants can form a stable hydrogel .

HY-135776

BMVC2 o-BMVC	G-quadruplex	Cancer
BMVC2 (o-BMVC) is a bisubstitute carbazole derivative of BMVC. BMVC2 is a G-quadruplex (G4) stabilizer .

HY-148012

SOP1812 QN-302	G-quadruplex	Cancer
SOP1812 (QN-302) is a naphthalene diimide (ND) derivative with anti-tumor activity. SOP1812 binds to quadruplex arrangements (G4s), and down-regulates several cancer gene pathways. SOP1812 shows great affinity to hTERT G4 and HuTel21 G4 with K_D values of 4.9 and 28.4 nM, respectively. SOP1812 can be used for the research of cancer .

HY-151263

G4/HDAC-IN-1	HDAC G-quadruplex	Cancer
G4/HDAC-IN-1 (compound a6) is a *G4/HDAC* dual-targeting compound. G4/HDAC-IN-1 inhibits intracellular HDAC activity with an IC₅₀ value of 1.1 μM, and induces G4 formation. G4/HDAC-IN-1 inhibits TNBC proliferation and tumor growth in TNBC xenograft model. G4/HDAC-IN-1 can be used for the research of cancer .

HY-160485

G-4'G-7S	Fluorescent Dye	Endocrinology
G-4'G-7S is a endogenous metabolite of genistein (HY-14596). G-4'G-7S can be used for the research of estrogenic activity .

HY-P1771

OVA G4 peptide	Biochemical Assay Reagents	Inflammation/Immunology
OVA G4 peptide is a variant of the agonist ovalbumin (OVA) peptide SIINFEKL (257-264). SIINFEKL is routinely used to stimulate ovalbumin-specific T cells and to test new vaccine adjuvants can form a stable hydrogel .

HY-146812

DIZ-3	G-quadruplex	Cancer
DIZ-3 is a selective multimeric G4 ligand based on a G4-ligand-dimerizing strategy. DIZ-3 intercalates into the G4-G4 interface, stabilizing the higher-order structure. DIZ-3 induces cell cycle arrest and apoptosis, and thus inhibits cell proliferation in alternative lengthening of telomere (ALT) cancer cells .

HY-161693

Telomeric G4s ligand 1	G-quadruplex DNA/RNA Synthesis Apoptosis	Cancer
Telomeric G4s ligand 1 is a telomeric G-quadruplex ligand that stabilizes telomeric G4 and induces R-loop formation, leading to DNA damage responses. Telomeric G4s ligand 1 induces apoptosis and evokes immunogenic cell death (ICD) in tumor cells .

HY-120102

Emicoron	G-quadruplex	Cancer
Emicoron is a new promising G4 ligand and bind G-rich oncogene promoters. Emicoron possesses a marked antitumoral activity? alone or in combination with chemotherapeutics in vivo. Emicoron can be used for cancer research .

HY-152538

Antitumor agent-85	G-quadruplex	Cancer
Antitumor agent-85 is a G-quadruplex (G4)-ligand with the ability to stabilize different G4-DNA structures. Antitumor agent-85 has highly effective anti-tumor properties .

HY-P99029

Magrolimab 2 Publications Verification Hu5F9-G4	CD47	Cancer
Magrolimab (Hu5F9-G4) is a humanized anti-CD47 antibody. Magrolimab can block the "don't eat me" signal of CD47, thereby promoting macrophage mediated phagocytosis. Magrolimab has antitumor activity in malignant bone tumors and breast cancer .

HY-152537

Antitumor agent-84	G-quadruplex	Cancer
Antitumor agent-84 (compound 21a) is a G-quadruplex (G4)-ligand with the ability to stabilize different G4-DNA structures. Antitumor agent-84 has highly effective anti-tumor properties .

HY-162294

c-Myc inhibitor 13	c-Myc	Cancer
c-Myc inhibitor 13 (compound A6) is a c-MYC transcription inhibitor. c-Myc inhibitor 13 selectively stabilizes c-MYC G4 and inhibits G4-associated c-MYC transcription .

HY-111297

BMVC4	Biochemical Assay Reagents	Cancer
BMVC4 is a G-quadruplex (G4) stabilizer of the human telomeric sequence d[AG3(T2AG3)3]. Screening by circular dichroism (CD) spectroscopy revealed that BMVC4 is more suitable as the core molecule of G4 stabilizers than BMVC. The results showed that BMVC4-12C and BMVC4-8C3O are better candidates for G4 stabilizers and are worthy of further study. A simple and rapid screening method based on Cu2+-induced G4 unfolding can be used to find better G4 stabilizers for potential anticancer applications. CD results showed that the trivalent cations of 9-substituted BMVC derivatives are more suitable as G4 stabilizers than the divalent cations of BMVC. In addition, by monitoring the disappearance of the 291 nm CD band of human telomeres after Cu2+ addition, it was found that the core molecule of G4 stabilizer BMVC4 has better stability.

HY-P99938

Pucotenlimab HX008	PD-1/PD-L1	Cancer
Pucotenlimab (HX008) is a humanized immunoglobulin G4 (IgG4) anti programmed cell death protein 1 (anti-PD-1) monoclonal antibody. Pucotenlimab can be used for the research of tumor .

HY-162796

TS-2	Apoptosis G-quadruplex c-Myc	Cancer
TS-2 is a fluorescent ligand of c-Myc G4 with anticancer activity. TS-2 inhibits the growth of cancer cells and induces apoptosis of cancer cells by targeting the c-MYC oncogene promoter G4, causing transcriptional repression of the c-Myc oncogene .

HY-P990753

Omoprubart	Complement System	Inflammation/Immunology
Omoprubart is an anti-C5 human IgG2-G4 κ monoclonal antibody .

HY-P990089

Patecibart Getagozumab; GMA-301	Endothelin Receptor	Cardiovascular Disease
Patecibart is a humanized immunoglobulin G4-kappa, anti-EDNRA monoclonal antibody. Patecibart is an endothelin receptor antagonist .

HY-P990074

Enlonstobart	PD-1/PD-L1	Inflammation/Immunology
Enlonstobart is a human immunoglobulin G4-kappa, anti-PDCD1 monoclonal antibody. Enlonstobart is an immunostimulant and antineoplastic .

HY-135775

BMVC 1 Publications Verification	G-quadruplex Telomerase DNA/RNA Synthesis	Cancer
BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor with an IC₅₀ of ~0.2 μM. BMVC inhibits Taq DNA polymerase with an IC₅₀ of ~2.5 μM. BMVC increases the melting temperature of G4 structure of telomere and accelerates telomere length shortening. Anticancer activities .

HY-P990095

Vonsetamig	CD3 TNF Receptor	Inflammation/Immunology Cancer
Vonsetamig is a humanised immunoglobulin G4-kappa, anti-TNFRSF17 and CD3E bispecific antibody. Vonsetamig is an antineoplastic .

HY-P990068

Perenostobart SRF617	NTPDase	Cancer
Perenostobart is a human immunoglobulin G4-kappa, anti-ENTPD1/CD39 monoclonal antibody. Perenostobart is an immunostimulant and antineoplastic .

HY-174403

c-MYC/BCL2 ligand 1 iodide	Bcl-2 Family c-Myc Apoptosis Caspase	Cancer
c-MYC/BCL2 ligand 1 iodide is a dual-targeting c-MYC/Bcl-2 G4 ligand with K_d values of 0.90 μM (c-MYC G4) and 0.56 μM (Bcl-2 G4). c-MYC/BCL2 ligand 1 iodide inhibits c-MYC and Bcl-2 gene transcription by binding to G4-forming sequences and downregulates their protein expression. c-MYC/BCL2 ligand 1 iodide inhibits suppresses migration, induces caspase-dependent apoptosis, and triggers cell cycle G1 arrest in MCF-7 cells. c-MYC/BCL2 ligand 1 iodide significantly suppresses tumor growth in a 4T1 syngeneic model with no observable toxicity. c-MYC/BCL2 ligand 1 iodide can be used for the research of breast cancer.

HY-15595

360A	G-quadruplex Telomerase	Cancer
360A is a selective stabilizer of G-quadruplex, and also inhibits telomerase activity with an IC₅₀ of 300 nM for telomerase in TRAP-G4 assay.

HY-P990092

Rolistobart	Transmembrane Glycoprotein	Cancer
Rolistobart is a humanized immunoglobulin G4-kappa, *anti-LILRB4/CD85k* monoclonal antibody. Rolistobart is an immunostimulant and antineoplastic .

HY-15595A

360A iodide 3 Publications Verification 360 A iodide	G-quadruplex Telomerase	Cancer
360A iodide is a selective stabilizer of G-quadruplex, and also inhibits telomerase activity with an IC₅₀ of 300 nM for telomerase in TRAP-G4 assay.

HY-168150

Topoisomerase I/II inhibitor 5	Topoisomerase	Cancer
Topoisomerase I/II inhibitor 5 (compund 1) simultaneously inhibits activities of TopoI and II by binding to and stabilizing the G4 structure .

HY-147973

IZTZ-1	c-Myc Apoptosis	Cancer
IZTZ-1, an imidazole-benzothiazole conjugate, is a c-MYC G4 ligand. IZTZ-1 is able to downregulate the c-MYC expression by stabilizing c-MYC G4. IZTZ-1 induces cell cycle arrest, apoptosis, thereby inhibiting cell proliferation in B16 cells. IZTZ-1 shows antitumor activity, and can be used for melanoma research .

HY-P991152

Oturkibart	Interleukin Related	Inflammation/Immunology
Oturkibart is a humanized immunoglobulin G4-κ monoclonal antibody targeting the human interleukin 4 receptor (IL4R). Oturkibart is promising for research of inflammatory diseases, such as asthma and atopic dermatitis .

HY-P99510

Zansecimab LY-3127804	Tie	Inflammation/Immunology Cancer
Zansecimab (LY-3127804) is an immunoglobulin G4-kappa, a monoclonal antibody against angiopoietin 2 (Ang 2). Zansecimab has potential applications in angiogenesis and immune regulation .

HY-176066A

c-Myc inhibitor 16 iodide	c-Myc Apoptosis	Cancer
c-Myc inhibitor 16 iodide (Compound W11) is a selective c-Myc G-quadruplex (c-Myc G4) inhibitor. c-Myc inhibitor 16 iodide inhibits the transcription and translation of the c-Myc gene, disrupts the tumor cell cycle, arrests cell growth in the G0/G1 phase and activates the mitochondrial apoptosis pathway to induce early apoptosis of cancer cells. c-Myc inhibitor 16 iodide is promising for research of breast cancer .

HY-P991137

Exerenibart	Ser/Thr Protease	Metabolic Disease
Exerenibart is an immunoglobulin G4-κ monoclonal antibody targeting human transmembrane serine protease 6 (TMPRSS6). Exerenibart is promising for research of diseases associated with iron metabolism disorders, such as iron overload or iron deficiency .

HY-15594

Phen-DC3	DNA/RNA Synthesis	Cancer
Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC₅₀s of 65±6 and 50±10 nM, respectively.

HY-15594A

Phen-DC3 Trifluoromethanesulfonate 5+ Cited Publications Phen-DC3 Triflate	G-quadruplex	Cancer
Phen-DC3 Trifluoromethanesulfonate is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC₅₀s of 65±6 and 50±10 nM, respectively.

HY-P991138

Firsekibart	Interleukin Related	Inflammation/Immunology
Firsekibart is an immunoglobulin G4-λ2 monoclonal antibody targeting human interleukin 1β (IL-1β). Firsekibart is promising for research of inflammation-related diseases, such as rheumatoid arthritis and inflammatory bowel disease .

HY-P99607

Clenoliximab IDEC-151	HIV	Inflammation/Immunology
Clenoliximab (IDEC-151) is a macaque-human chimeric monoclonal antibody (immunoglobulin G4) specific for the *CD4* molecule on the surface of T lymphocytes. Clenoliximab can be used for the research of rheumatoid arthritis .

HY-151471

Anticancer agent 84	c-Myc	Cancer
Anticancer agent 84 is an anticancer agent. Anticancer agent 84 represses the transcription of c-MYC by stabilizing the G-quadruplex (G4) structure. Anticancer agent 84 can be used for the research of cancer .

HY-P990921

Imelciment REGN-9035	Natriuretic Peptide Receptor (NPR)	Inflammation/Immunology
HY-P990921 is an NPR1-targeting half-IG G4 -κ/h-CH2-CH3 type human antibody .

HY-145843

c-Myc inhibitor 5	c-Myc	Cancer
c-Myc inhibitor 5 (DA3) is a fluorescent, long chain-bridged bispurine that selectively targets the c-MYC G-quadruplex (K_D of 16 μM). c-Myc inhibitor 5 shows inhibition on c-MYC expression rather than other G4-driven oncogenes .

HY-121862

CM03	DNA/RNA Synthesis	Cancer
CM03 is a potent DNA G-quadruplexes (G4s) ligand. CM03 can stabilise G4s, downregulating more G4-containing genes as well as increasing incidence of double-strand break events (DSBs) due to torsional strain on DNA and chromatin structure. CM03 has selective potency for pancreatic cancer cells .

HY-P99767

Olendalizumab ALXN1007	Complement System	Infection
Olendalizumab (ALXN1007) is a mouse-derived and humanized IgG2-G4-κ antibody, targeting to Complement protein C5a (K_i=60 pM). Olendalizumab targets the complement inflammatory pathway. Moreover, Olendalizumab can be used for research of complement mediated disorder caused by corona virus .

HY-P99114

Sugemalimab	PD-1/PD-L1	Cancer
Sugemalimab is a fully human, full length, anti-programmed death ligand 1 (PD-L1) immunoglobulin G4 (IgG4) monoclonal antibody (mAb). Sugemalimab shows anticancer activities and can be used for non-small cell lung cancer research .

HY-144712

L5-DA	G-quadruplex Apoptosis	Cancer
L5-DA is a G-quadruplex (G4) ligand and selectively stabilized for G4s over ds26. L5-DA exhibits significant cytotoxicity against HeLa cells (IC₅₀=4.3 μM). L5-DA stabilizes G4s in HeLa cells, induces apoptosis, and cell cycle arrest .

HY-135009

2-Di-1-ASP DASPI	G-quadruplex	Others
2-Di-1-ASP (DASPI; Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA .

HY-P991028

Surovatamig AZD0486; TNB-486	CD3	Inflammation/Immunology
HY-P991028 is an CD3D/CD3E/CD19-targeting (H-γ4_L-κ)_VH-G4(h-CH2-CH3) type bispecific antibody .

HY-149513

EP12	c-Myc Apoptosis	Cancer
EP12 is a c-Myc inhibitor. EP12 is a c-Myc G4 stabilizer. EP12 induces apoptosis and DNA damage in multiple myeloma cells. EP12 disrupts the nuclear translocation of P65/P50 by interfering with the NF-κB signaling pathway. EP12 inhibits multiple myeloma growth .

HY-158049

Anticancer agent 199	Apoptosis Ferroptosis	Cancer
Anticancer agent 199 (Compound G-4) induces apoptosis in triple negative breast cancer (TNBC) cells via the mitochondrial pathway through inhibiting EGFR, AKT and MAPK pathways. Anticancer agent 199 also induces Ferroptosis by down-regulating LCN2. Anticancer agent 199 inhibits TNBC cell viability and migration, and induces S phase cell cycle arrest. Anticancer agent 199 is a derivate of cyclin-dependent kinase inhibitor Rocovitine .

HY-168886

Anticancer agent 263	c-Myc	Cancer
Anticancer agent 263 (compound 7) is a potent anticancer agent. Anticancer agent 263 binds to the G-quadruplex DNA (G4) sequence 22-mer Pu22, a mimic of c-Myc DNA. Anticancer agent 263 is a structure modulator, showcasing a significant enhancement in protein α-helix formation and the capability to form supramolecular network. Anticancer agent 263 shows no cytotoxicity .

Cat. No.	Product Name	Type

HY-135009

2-Di-1-ASP DASPI	Fluorescent Dyes/Probes
2-Di-1-ASP (DASPI; Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA .

HY-D2380

H2S probe 1	Fluorescent Dyes/Probes
H2S probe 1 (compound 1NND) is a derivative of nitrobenzoxadiazole (NBD) with antitumor activity. H2S probe 1 is cytotoxic to human pancreatic cancer cell MIA PaCa-2 (IC₅₀=77.9 nM) and has a high affinity for human telomeric G-quadruplex (G4) (K_d=1.72 μM). H2S probe 1 can be used in cancer research .

Cat. No.	Product Name	Type

HY-158490

A4G4 glycan A4G4 N-linked oligosaccharide	Carbohydrates
A4G4 glycan (A4G4 N-linked oligosaccharide) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158492

A4G4 glycan, 2-AB labelled A4G4 N-linked oligosaccharide, 2-AB labelled	Carbohydrates
A4G4 glycan, 2-AB labelled (A4G4 N-linked oligosaccharide, 2-AB labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158491

A4G4 glycan, 2-AA labelled A4G4 N-linked oligosaccharide, 2-AA labelled	Carbohydrates
A4G4 glycan, 2-AA labelled (A4G4 N-linked oligosaccharide, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158442

A2G2 glycan (G2) A2G2 N-linked oligosaccharide; A2G(4)2 glycan	Carbohydrates
A2G2 glycan (G2) (A2G2 N-linked oligosaccharide; A2G(4)2 glycan) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158452

A3G3 glycan (G3) A3G3 N-linked oligosaccharide; A3G(4)3 glycan	Carbohydrates
A3G3 glycan (G3) (A3G3 N-linked oligosaccharide; A3G(4)3 glycan) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158489

A3G3 glycan (G3), procainamide labelled A3G3 N-linked oligosaccharide, procainamide labelled; A3G(4)3 glycan, procainamide labelled	Carbohydrates
A3G3 glycan (G3), procainamide labelled (A3G3 N-linked oligosaccharide, procainamide labelled; A3G(4)3 glycan, procainamide labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158447

A2G2 glycan (G2), procainamide labelled A2G2 N-linked oligosaccharide, procainamide labelled; A2G(4)2 glycan, procainamide labelled	Carbohydrates
A2G2 glycan (G2), procainamide labelled (A2G2 N-linked oligosaccharide, procainamide labelled; A2G(4)2 glycan, procainamide labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158506

A2G2S2 glycan (G2S2) A2G2S2 N-linked oligosaccharide; A2G(4)2S(6)2 glycan	Carbohydrates
A2G2S2 glycan (G2S2) (A2G2S2 N-linked oligosaccharide; A2G(4)2S(6)2 glycan) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158475

A2G2S1 glycan (G2S1) A2G2S1 N-linked oligosaccharide; A2G(4)2S(6)1 glycan	Carbohydrates
A2G2S1 glycan (G2S1) (A2G2S1 N-linked oligosaccharide; A2G(4)2S(6)1 glycan) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158513

FA2G2S2 glycan (G2FS2) FA2G2S2 N-linked oligosaccharide; F(6)A2G(4)2S(6)2 glycan	Carbohydrates
FA2G2S2 glycan (G2FS2) (FA2G2S2 N-linked oligosaccharide; F(6)A2G(4)2S(6)2 glycan) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158510

A2G2S2 glycan (G2S2), APTS labelled A2G2S2 N-linked oligosaccharide, APTS labelled; A2G(4)2S(6)2 glycan, APTS labelled	Carbohydrates
A2G2S2 glycan (G2S2), APTS labelled (A2G2S2 N-linked oligosaccharide, APTS labelled; A2G(4)2S(6)2 glycan, APTS labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158517

FA2G2S2 glycan (G2FS2), APTS labelled FA2G2S2 N-linked oligosaccharide, APTS labelled; F(6)A2G(4)2S(6)2 glycan, APTS labelled	Carbohydrates
FA2G2S2 glycan (G2FS2), APTS labelled (FA2G2S2 N-linked oligosaccharide, APTS labelled; F(6)A2G(4)2S(6)2 glycan, APTS labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158508

A2G2S2 glycan (G2S2), 2-AA labelled A2G2S2 N-linked oligosaccharide, 2-AA labelled; A2G(4)2S(6)2 glycan, 2-AA labelled	Carbohydrates
A2G2S2 glycan (G2S2), 2-AA labelled (A2G2S2 N-linked oligosaccharide, 2-AA labelled; A2G(4)2S(6)2 glycan, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158512

A2G2S2 glycan (G2S2), 2-AB labelled A2G2S2 N-linked oligosaccharide, 2-AB labelled; A2G(4)2S(6)2 glycan, 2-AB labelled	Carbohydrates
A2G2S2 glycan (G2S2), 2-AB labelled (A2G2S2 N-linked oligosaccharide, 2-AB labelled; A2G(4)2S(6)2 glycan, 2-AB labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158515

FA2G2S2 glycan (G2FS2), 2-AB labelled FA2G2S2 N-linked oligosaccharide, 2-AB labelled; F(6)A2G(4)2S(6)2 glycan, 2-AB labelled	Carbohydrates
FA2G2S2 glycan (G2FS2), 2-AB labelled (FA2G2S2 N-linked oligosaccharide, 2-AB labelled; F(6)A2G(4)2S(6)2 glycan, 2-AB labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158518

FA2G2S2 glycan (G2FS2), 2-AA labelled FA2G2S2 N-linked oligosaccharide, 2-AA labelled; F(6)A2G(4)2S(6)2 glycan, 2-AA labelled	Carbohydrates
FA2G2S2 glycan (G2FS2), 2-AA labelled (FA2G2S2 N-linked oligosaccharide, 2-AA labelled; F(6)A2G(4)2S(6)2 glycan, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158477

FA2G2S1 glycan (G2FS1) FA2G2S1 N-linked oligosaccharide; α(2,6)/FA2G2S(6)1 glycan; F(6)A2G(4)2S(6)1 glycan	Carbohydrates
FA2G2S1 glycan (G2FS1) (FA2G2S1 N-linked oligosaccharide; α(2,6)/FA2G2S(6)1 glycan; F(6)A2G(4)2S(6)1 glycan) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-158476

FA2G2S1 glycan (G2FS1), procainamide labelled FA2G2S1 N-linked oligosaccharide, procainamide labelled; α(2,6)/FA2G2S(6)1 glycan, procainamide labelled; F(6)A2G(4)2S(6)1 glycan, procainamide labelled	Carbohydrates
FA2G2S1 glycan (G2FS1), procainamide labelled (FA2G2S1 N-linked oligosaccharide, procainamide labelled; α(2,6)/FA2G2S(6)1 glycan, procainamide labelled; F(6)A2G(4)2S(6)1 glycan, procainamide labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

Cat. No.	Product Name	Target	Research Area

HY-P6022

G4RGDSP, integrin-binding peptide	Integrin	Others
G4RGDSP, Integrin-binding peptide is a cell integrin-binding peptide that targets integrin receptors. G4RGDSP, integrin-binding peptide is coupled to alginate to increase the viability of cells in the scaffold. G4RGDSP, integrin-binding peptide can be used as an extrudable carrier for chondrocyte delivery for the study of 3D printing technology

HY-P1771A

OVA G4 peptide TFA	Biochemical Assay Reagents	Inflammation/Immunology
OVA G4 peptide TFA is a variant of the agonist ovalbumin (OVA) peptide SIINFEKL (257-264). SIINFEKL is routinely used to stimulate ovalbumin-specific T cells and to test new vaccine adjuvants can form a stable hydrogel .

HY-20841

Boc-(2S)-Gly-4-pyranoyl (S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid; Boc-4-Pyranoyl-Gly-OH	Amino Acid Derivatives	Others
Boc-(2S)-Gly-4-pyranoyl ((S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid) is an amino-terminally protected glycine derivative that can be used to synthesize dipeptidyl peptidase IV with antidiabetic activity .

HY-P1771

OVA G4 peptide	Biochemical Assay Reagents	Inflammation/Immunology
OVA G4 peptide is a variant of the agonist ovalbumin (OVA) peptide SIINFEKL (257-264). SIINFEKL is routinely used to stimulate ovalbumin-specific T cells and to test new vaccine adjuvants can form a stable hydrogel .

Cat. No.	Product Name	Target	Research Area

HY-P99029

Magrolimab 2 Publications Verification Hu5F9-G4	CD47	Cancer
Magrolimab (Hu5F9-G4) is a humanized anti-CD47 antibody. Magrolimab can block the "don't eat me" signal of CD47, thereby promoting macrophage mediated phagocytosis. Magrolimab has antitumor activity in malignant bone tumors and breast cancer .

HY-P99938

Pucotenlimab HX008	PD-1/PD-L1	Cancer
Pucotenlimab (HX008) is a humanized immunoglobulin G4 (IgG4) anti programmed cell death protein 1 (anti-PD-1) monoclonal antibody. Pucotenlimab can be used for the research of tumor .

HY-P990095

Vonsetamig	CD3 TNF Receptor	Inflammation/Immunology Cancer
Vonsetamig is a humanised immunoglobulin G4-kappa, anti-TNFRSF17 and CD3E bispecific antibody. Vonsetamig is an antineoplastic .

HY-P990068

Perenostobart SRF617	NTPDase	Cancer
Perenostobart is a human immunoglobulin G4-kappa, anti-ENTPD1/CD39 monoclonal antibody. Perenostobart is an immunostimulant and antineoplastic .

HY-P990081

Oloctinebart TB-006	Inhibitory Antibodies	Neurological Disease
Oloctinebart is a humanized immunoglobulin G4-kappa, anti-LGALS3 monoclonal antibody. Oloctinebart is used for reduction of amyloid beta oligomers formation .

HY-P990092

Rolistobart	Transmembrane Glycoprotein	Cancer
Rolistobart is a humanized immunoglobulin G4-kappa, *anti-LILRB4/CD85k* monoclonal antibody. Rolistobart is an immunostimulant and antineoplastic .

HY-P990753

Omoprubart	Complement System	Inflammation/Immunology
Omoprubart is an anti-C5 human IgG2-G4 κ monoclonal antibody .

HY-P990089

Patecibart Getagozumab; GMA-301	Endothelin Receptor	Cardiovascular Disease
Patecibart is a humanized immunoglobulin G4-kappa, anti-EDNRA monoclonal antibody. Patecibart is an endothelin receptor antagonist .

HY-P990074

Enlonstobart	PD-1/PD-L1	Inflammation/Immunology
Enlonstobart is a human immunoglobulin G4-kappa, anti-PDCD1 monoclonal antibody. Enlonstobart is an immunostimulant and antineoplastic .

HY-P991152

Oturkibart	Interleukin Related	Inflammation/Immunology
Oturkibart is a humanized immunoglobulin G4-κ monoclonal antibody targeting the human interleukin 4 receptor (IL4R). Oturkibart is promising for research of inflammatory diseases, such as asthma and atopic dermatitis .

HY-P99510

Zansecimab LY-3127804	Tie	Inflammation/Immunology Cancer
Zansecimab (LY-3127804) is an immunoglobulin G4-kappa, a monoclonal antibody against angiopoietin 2 (Ang 2). Zansecimab has potential applications in angiogenesis and immune regulation .

HY-P991137

Exerenibart	Ser/Thr Protease	Metabolic Disease
Exerenibart is an immunoglobulin G4-κ monoclonal antibody targeting human transmembrane serine protease 6 (TMPRSS6). Exerenibart is promising for research of diseases associated with iron metabolism disorders, such as iron overload or iron deficiency .

HY-P991138

Firsekibart	Interleukin Related	Inflammation/Immunology
Firsekibart is an immunoglobulin G4-λ2 monoclonal antibody targeting human interleukin 1β (IL-1β). Firsekibart is promising for research of inflammation-related diseases, such as rheumatoid arthritis and inflammatory bowel disease .

HY-P99607

Clenoliximab IDEC-151	HIV	Inflammation/Immunology
Clenoliximab (IDEC-151) is a macaque-human chimeric monoclonal antibody (immunoglobulin G4) specific for the *CD4* molecule on the surface of T lymphocytes. Clenoliximab can be used for the research of rheumatoid arthritis .

HY-P990921

Imelciment REGN-9035	Natriuretic Peptide Receptor (NPR)	Inflammation/Immunology
HY-P990921 is an NPR1-targeting half-IG G4 -κ/h-CH2-CH3 type human antibody .

HY-P99767

Olendalizumab ALXN1007	Complement System	Infection
Olendalizumab (ALXN1007) is a mouse-derived and humanized IgG2-G4-κ antibody, targeting to Complement protein C5a (K_i=60 pM). Olendalizumab targets the complement inflammatory pathway. Moreover, Olendalizumab can be used for research of complement mediated disorder caused by corona virus .

HY-P991230

MK-4830	Inhibitory Antibodies	Cancer
MK-4830 is a fully humanized monoclonal antibody of the immunoglobulin G4 subclass that specifically binds to *ILT4* and blocks its interaction with HLA-G and other ligands. MK-4830 inhibits tumor growth in humanized mouse cancer models .

HY-P99114

Sugemalimab	PD-1/PD-L1	Cancer
Sugemalimab is a fully human, full length, anti-programmed death ligand 1 (PD-L1) immunoglobulin G4 (IgG4) monoclonal antibody (mAb). Sugemalimab shows anticancer activities and can be used for non-small cell lung cancer research .

HY-P991028

Surovatamig AZD0486; TNB-486	CD3	Inflammation/Immunology
HY-P991028 is an CD3D/CD3E/CD19-targeting (H-γ4_L-κ)_VH-G4(h-CH2-CH3) type bispecific antibody .

HY-P990181

Anti-Mouse myeloperoxidase/MPO Antibody (6G4)	Glutathione Peroxidase STING	Inflammation/Immunology
Anti-Mouse myeloperoxidase/MPO Antibody (6G4) is an anti-mouse myeloperoxidase/MPO IgG2c monoclonal antibody. Anti-Mouse myeloperoxidase/MPO Antibody (6G4) can activate the cGAS/STING pathway. Anti-Mouse myeloperoxidase/MPO Antibody (6G4) induces acute and chronic kidney injury in mice. Anti-Mouse myeloperoxidase/MPO Antibody (6G4) is often used in the construction of inflammation conditions models such as anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) .

HY-P990151

Anti-Mouse TL1A/TNFSF15 Antibody (5G4.6)	TNF Receptor	Inflammation/Immunology
Anti-Mouse TL1A/TNFSF15 Antibody (5G4.6) is an anti-mouse TL1A/TNFSF15 IgG monoclonal antibody. Anti-Mouse TL1A/TNFSF15 Antibody (5G4.6) can reduce TL1A levels and block TL1A-DR3 interactions. Anti-Mouse TL1A/TNFSF15 Antibody (5G4.6) can be used for research on inflammation conditions such as colitis and collagen-induced arthritis (CIA) .

HY-P991184

Anti-LY6G6D Antibody (1G4)	Inhibitory Antibodies	Cancer
Anti-LY6G6D Antibody (1G4) is a humanized IgG1 monoclonal antibody that targets LY6G6D. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990981

Clesitamig	Inhibitory Antibodies	Inflammation/Immunology
HY-P990981 is an DLL3-targeting (V-κ-G4CH1-G1h-H-γ1_L-κ)_Lκ)]_(H-γ1_L-κ) type humanized antibody .

Species:	Human (3)
Tag:	His (3) SUMO (1)
Source:	E. coli (1) P. pastoris (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P75726

	EBP1 Protein, Human (His) Proliferation-associated protein 2G4; hG4-1; ErbB3-binding protein 1; PA2G4	Human	E. coli
	EBP1 protein participates in the signal transduction pathway regulated by ERBB3 and is related to growth regulation. As an androgen receptor (AR) corepressor, it is regulated by the ERBB3 ligand neregulin-1/heregulin (HRG). EBP1 Protein, Human (His) is the recombinant human-derived EBP1 protein, expressed by E. coli , with N-His labeled tag.

HY-P702611

	Arylsulfatase B/ARSB Protein, Human (His-SUMO) Arylsulfatase B; ASB; N-acetylgActosamine-4-sulfatase; G4S	Human	E. coli
	The arylsulfatase B (ARSB) protein is critical for cellular homeostasis by removing the sulfate group from chondroitin 4-sulfate (C4S), thereby directing its degradation. Its enzymatic activity affects the adhesion, migration and invasion of colon epithelial cells. Arylsulfatase B/ARSB Protein, Human (His-SUMO) is the recombinant human-derived Arylsulfatase B/ARSB, expressed by E. coli Cell-free, with N-SUMO, N-6His labeled tag. The total length of Arylsulfatase B/ARSB Protein, Human (His-SUMO) is 497 a.a.*.

HY-P702612

	Arylsulfatase B/ARSB Protein, Human (P.pastoris, His) Arylsulfatase B; ASB; N-acetylgActosamine-4-sulfatase; G4S	Human	P. pastoris
	The arylsulfatase B (ARSB) protein is critical for cellular homeostasis by removing the sulfate group from chondroitin 4-sulfate (C4S), thereby directing its degradation. Its enzymatic activity affects the adhesion, migration and invasion of colon epithelial cells. Arylsulfatase B/ARSB Protein, Human (P.pastoris, His) is the recombinant human-derived Arylsulfatase B/ARSB, expressed by P. pastoris, with N-6His labeled tag. The total length of Arylsulfatase B/ARSB Protein, Human (P.pastoris, His) is 497 a.a.*.

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Species
Source
Tag
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HY-P82764

	EBP1 Antibody (YA2509) PA2G4; EBP1; Proliferation-associated protein 2G4; Cell cycle protein p38-2G4 homolog; hG4-1; ErbB3-binding protein 1	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	EBP1 Antibody (YA2509) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2509), targeting EBP1, with a predicted molecular weight of 44 kDa (observed band size: 48 kDa). EBP1 Antibody (YA2509) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P85609

	Human IgG Antibody (YA5301) FLJ39988; FLJ40036; FLJ40253; FLJ40587; FLJ40789; FLJ40834; G1m marker; G2m marker; G3m marker; G4m marker; HDC; Heavy chain disease protein; Human immunglobulin G; Ig gamma 1 chain C region; Ig gamma 2 chain C region; Ig gamma 3 chain C region.	ELISA	Human
	Human IgG Antibody (YA5301) is a mouse-derived and non-conjugated monoclonal antibody, targeting to IgG. It can be applicated for ELISA assays, in the background of human.

HY-P87025

	Phospho-Cytosolic Phospholipase A2 (S505) Antibody (YA6718) Calcium dependent phospholipid binding protein antibody; CPLA 2 antibody; cPLA2 alpha antibody; cPLA2 antibody; Cytosolic phospholipase A2 antibody; Cytosolic phospholipase A2 group IVA antibody; Lysophospholipase antibody; MGC126350 antibody; PA24A_HUMAN antibody; Phosphatidylcholine 2 acylhydrolase antibody; Calcium dependent phospholipid binding protein antibody; CPLA 2 antibody; cPLA2 alpha antibody; cPLA2 antibody; Cytosolic phospholipase A2 antibody; Cytosolic phospholipase A2 group IVA antibody; Lysophospholipase antibody; MGC126350 antibody; PA24A_HUMAN antibody; Phosphatidylcholine 2 acylhydrolase antibody; Phosphatidylcholine 2-acylhydrolase antibody; Phospholipase A2 group 4 A antibody; Phospholipase A2 group IVA (cytosolic calcium dependent) antibody; Phospholipase A2 group IVA antibody; PhospholipaseA2 antibody; PLA2G4 antibody; pla2G4a antibody	WB, Dot Blot	Human, Mouse

HY-P86972

	Mouse anti-Human IgG Antibody (YA6665) FLJ39988 antibody; FLJ40036 antibody; FLJ40253 antibody; FLJ40587 antibody; FLJ40789 antibody; FLJ40834 antibody; G1m marker antibody; G2m marker antibody; G3m marker antibody; G4m marker antibody; FLJ39988 antibody; FLJ40036 antibody; FLJ40253 antibody; FLJ40587 antibody; FLJ40789 antibody; FLJ40834 antibody; G1m marker antibody; G2m marker antibody; G3m marker antibody; G4m marker antibody; HDC antibody; Heavy chain disease protein antibody; Human immunglobulin G antibody; Ig gamma 1 chain C region antibody; Ig gamma 2 chain C region antibody; Ig gamma 3 chain C region antibody; Ig gamma 4 chain C region antibody; IgG heavy chain locus antibody; IGHG 1 antibody; IGHG 2 antibody; IGHG 3 antibody; IGHG 4 antibody; IGHG1 antibody; IGHG2 antibody; IGHG3 antibody; IGHG4 antibody; Immunoglobulin Gm1 antibody; Immunoglobulin Gm3 antibody; Immunoglobulin Gm4 antibody; immunoglobulin heavy constant gamma 1 (G1m marker) antibody; Immunoglobulin heavy constant gamma 1 antibody; immunoglobulin heavy constant gamma 2 (G2m marker) antibody; Immunoglobulin heavy constant gamma 2 antibody; immunoglobulin heavy constant gamma 3 (G3m marker) antibody; Immunoglobulin heavy constant gamma 3 antibody; immunoglobulin heavy constant gamma 4 (G4m marker) antibody; Immunoglobulin heavy constant gamma 4 antibody; MGC117419 antibody; MGC45809 antibody	WB, ELISA	Human

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