Search Result

Results for "

DPPH radical

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA Carboxylase (1) Adenosine Receptor (1) Akt (4) Aldose Reductase (2) AMPK (2) Amylases (3) Amyloid-β (1) Antibiotic (1) AP-1 (2) Apoptosis (9) Aryl Hydrocarbon Receptor (1) Autophagy (5) Bacterial (11) Bcl-2 Family (1) Biochemical Assay Reagents (1) Cannabinoid Receptor (1) Caspase (2) Cholinesterase (ChE) (6) COX (7) Cytochrome P450 (2) Drug Intermediate (2) Drug Metabolite (2) EGFR (3) Elastase (1) Endogenous Metabolite (8) ERK (1) Fatty Acid Synthase (FASN) (1) Ferroptosis (1) Fluorescent Dye (1) Fungal (7) FXR (1) Glycosidase (2) HIV (2) HMG-CoA Reductase (HMGCR) (1) HSV (2) IFNAR (3) Influenza Virus (1) Interleukin Related (6) Isotope-Labeled Compounds (2) JNK (2) Keap1-Nrf2 (1) Lipoxygenase (3) Microphthalmia Associated Transcription Factor (MITF) (1) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) MMP (1) Monoamine Oxidase (3) NF-κB (1) NO Synthase (8) NOD-like Receptor (NLR) (1) Nucleoside Antimetabolite/Analog (1) p38 MAPK (5) Parasite (1) PD-1/PD-L1 (2) PERK (2) Phosphodiesterase (PDE) (1) PI3K (2) PKA (1) PPAR (1) Raf (1) Ras (2) Reactive Oxygen Species (ROS) (38) Reference Standards (8) Reverse Transcriptase (2) SOD (2) STAT (2) Tim3 (2) TNF Receptor (4) TRP Channel (2) TrxR (1) Tyrosinase (8) URAT1 (1) Urease (1) Wnt (2) Xanthine Oxidase (1) α-synuclein (1)
By Research Areas:	Cancer (33) Cardiovascular Disease (6) Infection (21) Inflammation/Immunology (61) Metabolic Disease (24) Neurological Disease (21)
Click Chemistry:	Azide (1) Alkynes (1)

136

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N9895

3,5-Dicaffeoyl-epi-quinic acid	Others	Infection Inflammation/Immunology
3,5-Dicaffeoyl-epi-quinic acid can be extracted from Chrysanthemum morifolium. 3,5-Dicaffeoyl-epi-quinic acid has antioxidant activities. 3,5-Dicaffeoyl-epi-quinic acid can scavenge *DPPH* radical and superoxide anion radical, with IC₅₀s of 5.6 and 2.9 μg/mL respectively .

HY-N8194

Syringetin-3-O-glucoside Syringetin 3-O-β-D-glucoside	Others	Neurological Disease
Syringetin-3-O-glucosid (Syringetin 3-O-β-D-glucoside), a flavonol glycoside, shows relatively weak DPPH and ABTS radical scavenging activity .

HY-N3985

Gyrophoric acid	Others	Cancer
Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows DPPH radical scavenging activity with an IC₅₀ value of 105.75 μg/ml .

HY-N8579

Eugenyl benzoate	Others	Inflammation/Immunology
Eugenyl benzoate has the potency for scavenging of *DPPH* radical. Eugenyl Benzoate Derivatives can be used for development of BCL-2 inhibitors .

HY-N9953

Chrysophanol 8-O-β-D-(6′-O-galloyl)glucopyranoside	Others	Inflammation/Immunology
Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside, an anthraquinone glucoside, can be isolated from Rheum undulatum L. Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside has potent DPPH radical and ?O₂ ^- scavenging activity .

HY-N10985

Xanthone V1a	Others	Inflammation/Immunology Cancer
Xanthone V1a has antioxidant activity against the *DPPH* radical (IC₅₀: 10.43 µM). Xanthone V1a has cytotoxicity against cancer cells .

HY-111523

Isomahanine	p38 MAPK Apoptosis Autophagy Caspase	Metabolic Disease
Isomahanine, carbazole alkaloid, is an antioxidative agent. Isomahanine has DPPH radical scavenging activity with an IC₅₀ value of 24 μM .

HY-N7518

Eulophiol	Others	Inflammation/Immunology
Eulophiol shows the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity with an EC₅₀ of 27.7μM. Antioxidant activity .

HY-N10020

Patulitrin	Lipoxygenase	Inflammation/Immunology
Patulitrin has scavenging effect in the DPPH radical. Patulitrin inhibits soybean lipoxygenase. Patulitrin also has antihypertensive effect. Patulitrin is an antioxidant flavonoid that can be isolated from Anthemis tinctoria .

HY-N9051

6-Prenylquercetin-3-Me ether	Glycosidase	Inflammation/Immunology Cancer
6-Prenylquercetin-3-Me ether is a natural product that can be extracted from G. uralensis leaves. 6-Prenylquercetin-3-Me ether has radical scavenging activity toward *DPPH. 6-Prenylquercetin-3-Me ether also has inhibitory activity against α-glucosidase* .

HY-W357738

Urease-IN-14	Bacterial Urease	Infection
Urease-IN-14 (compound 15) is an urease inhibitor and antioxidant. Urease-IN-14 shows DPPH radical scavenging and urease inhibitory activities with IC₅₀ values 151.7 μM and 41.6 μM, respectively .

HY-149670

Ferroptosis-IN-3	Ferroptosis	Inflammation/Immunology
Ferroptosis-IN-3 (Compound 25) is a ferroptosis inhibitor. Ferroptosis-IN-3 inhibits RSL3-induced ferroptosis (EC₅₀: 8.6?nM in HT-1080?cells). Ferroptosis-IN-3 scavenges DPPH and ABTS radicals (EC₅₀: 3.94?and 6.3 μM respectively). Ferroptosis-IN-3 decreases lipid peroxidation .

HY-W002773

Methyl isovanillate	Endogenous Metabolite	Others
Methyl isovanillate is a secondary metabolite isolated from Vitex agnus-castus. Methyl isovanillate does not exhibit significant activity in the DPPH* free radical scavenging experiment* .

HY-N10294

Epicoccone B	HIV	Infection Inflammation/Immunology
Epicoccone B, firstly reported from C. globosum, exhibits the DPPH free radical scavenging ability with IC₅₀ value of 10.8 μM, and has potent α-glucosidase inhibition with IC₅₀ value of 27.3 μM. Anti-HIV activity .

HY-N3554

Catechin-7-O-β-D-xylopyranoside (+)-Catechol 7-β-D-xylopyranoside	Others	Others
Catechin-7-O-β-D-xylopyranoside is an antioxidant compound with strong DPPH free radical scavenging ability. Catechin-7-O-β-D-xylopyranoside can be extracted from birch inner bark and nepeta stem bark .

HY-P5318

MDYYFEER	Reactive Oxygen Species (ROS)	Inflammation/Immunology
MDYYFEER is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER has high DPPH and ABTS radical scavenging ability. MDYYFEER protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-N10770

5'-Geranyl-5,7,2',4'-tetrahydroxyflavone	Others	Metabolic Disease
5'-Geranyl-5,7,2',4'-tetrahydroxyflavone, a phenolic compound, presents strong oxygen radical absorbance capacity (ORAC), DPPH radical-scavenging capacity, ABTS radical-scavenging capacity, ferric reducing antioxidant power (FRAP) and nitrite-scavenging capacity. 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone has the potential for natural antioxidant research .

HY-P5317

MAQAAEYYR	Reactive Oxygen Species (ROS)	Inflammation/Immunology
MAQAAEYYR is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-N10927

2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene	Others	Others
2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene, a diterpenoid, has significant effects on DPPH radical scavenging activity with an IC₅₀ value of 20.0 µM. 2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene shows potent antioxidant activity .

HY-N13142

Luteolin 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside	Others	Inflammation/Immunology
Luteolin 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside (compound 3) is a flavonoid with antioxidant activity, which can be isolated from Margaritopsis carrascoana. Luteolin 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside has good DPPH free radical scavenging activity (IC50=0.188 mg/mL) .

HY-P5317A

MAQAAEYYR TFA	Reactive Oxygen Species (ROS)	Inflammation/Immunology
MAQAAEYYR TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR TFA has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-111898

Epirosmanol	Others	Cancer
Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity .

HY-N15727

2,5-Dimethylchromone-7-O-β-D-glucopyranoside	Others	Inflammation/Immunology
2,5-Dimethylchromone-7-O-β-D-glucopyranoside is an orally active chromone glycoside found in the underground parts of Rheum australe. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside shows a DPPH radical scavenging activity with an IC₅₀ value of 66.9 μM. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside scavenges free radicals by providing hydrogen atoms through phenolic hydroxyl groups, inhibiting lipid peroxidation. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside is promising for research of oxidative stress-related diseases such as inflammation and skin diseases .

HY-W001542R

5-Hydroxyoxindole (Standard)	Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease Cancer
5-Hydroxyoxindole is a structural analog of uric acid for its antioxidant. 5-Hydroxyoxindole has DPPH radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole is a product of partial metabolism of tryptophan involving conversion in the gut lumen of tryptophan to indole through the action of bacterial tryptophanase and tryptophan synthase. 5-Hydroxyoxindole is one of the main molecules responsible for the neurological symptoms of hepatic encephalopathy in rats. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders .

HY-W001542

5-Hydroxyoxindole	Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease Cancer
5-Hydroxyoxindole is a structural analog of uric acid for its antioxidant. 5-Hydroxyoxindole has *DPPH* radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole is a product of partial metabolism of tryptophan involving conversion in the gut lumen of tryptophan to indole through the action of bacterial tryptophanase and tryptophan synthase. 5-Hydroxyoxindole is one of the main molecules responsible for the neurological symptoms of hepatic encephalopathy in rats. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders .

HY-N11845

Sigmoidin B	Lipoxygenase	Metabolic Disease Inflammation/Immunology
Sigmoidin B, a prenylated flavanone, is a selective 5-lipoxygenase inhibitor. Sigmoidin B is a potent scavenger of the DPPH radical. Sigmoidin B has antigenotoxic activity that inhibits genotoxicity induced by Aflatoxin B1 (HY-N6615), with an IC₅₀ of 18.7 μg/mL. Sigmoidin B has anti-inflammatory activity and antioxidant properties .

HY-N10295

Flavipin	Aryl Hydrocarbon Receptor	Inflammation/Immunology
Flavipin is an aryl hydrocarbon receptor (Ahr) agonist that induces the expression of Ahr downstream genes in mouse CD4 ⁺ T cells and CD11b ⁺ macrophages. Flavipin inhibits the stabilizing function of Arid5a on Il23a 3′UTR, a newly identified target mRNA . Flavipin exhibits the DPPH free radical scavenging ability with IC₅₀ value of 7.2 μM, and has potent α-glucosidase inhibition with IC₅₀ value of 33.8 μM .

HY-N0025

Jionoside D	Reactive Oxygen Species (ROS) Apoptosis	Metabolic Disease
Jionoside D is a hydroxycinnamic acid ester with antioxidant property. Jionoside D has scavenging activity of intracellular reactive oxygen species (ROS) and of DPPH radical, and lipid peroxidation inhibitory activity. Jionoside D reduces the apoptotic cells induced by H₂O₂ in V79-4 cells. Jionoside D increases the activities of cellular antioxidant enzymes, SOD and catalase .

HY-149390

TrxR1-IN-1	TrxR	Cancer
TrxR1-IN-1 (Compound 5j) is a TrxR1 inhibitor (IC₅₀: 8.8 μM). TrxR1-IN-1 has anticancer activity, with IC₅₀s of MCF-7 (1.5 μM), HeLa (1.7 μM), BGC-823 (2.4 μM), SW-480 (2.8 μM), A549 (2.1 μM). TrxR1-IN-1 has antioxidant activity, and scavenges DPPH radical .

HY-146172

Antioxidant agent-3	Reactive Oxygen Species (ROS)	Inflammation/Immunology Cancer
Antioxidant agent-3 (Compound 14q), an potent antioxidant, displays potent DPPH radicals scavenging activity and ABTS ⁺ scavenging activity with IC₅₀s of 26.58 and 30.31 μM, respectively. Antioxidant agent-3 (Compound 14q) increases reactive oxygen species (ROS), superoxide dismutase (SOD) and glutathione (GSH), and reduced lactate dehydrogenase (LDH) in H₂O₂-treated HepG2 cells .

HY-N9814

Shanciol B	NO Synthase	Inflammation/Immunology
Shanciol B, isolated from the ethyl acetate extract of the air-dried whole plant of Pholidota imbricate Hook, inhibits nitric oxide (NO) production and 1,1-diphenyl-2-picrylhydrazil (DPPH) radical scavenging activity . Shanciol B is a microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor with anti-inflammatory activity .

HY-121153

Altenusin Alutenusin	FXR	Others
Altenusin shows markedly DPPH radical scavenging activities.

HY-112053R

DPPH (Standard) 2,2-Diphenyl-1-picrylhydrazyl (Standard)	Reactive Oxygen Species (ROS) Reference Standards	Metabolic Disease
DPPH (Standard) is the analytical standard of DPPH. This product is intended for research and analytical applications. DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .

HY-155346

Free radical scavenger 1	Others	Others
Free radical scavenger 1 (compound 8) shows scavenging activity against the *DPPH* radical, with the IC₅₀ of 43.39 μg/ml .

HY-133183

Urolignoside	Biochemical Assay Reagents	Others
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model .

HY-112053

DPPH Maximum Cited Publications 40 Publications Verification 2,2-Diphenyl-1-picrylhydrazyl	Reactive Oxygen Species (ROS)	Metabolic Disease
DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .

HY-N3141

Olivil (-)-Olivile; Vladinol C	Others	Others
Olivil ((-)-Olivile) is a lignan that has weak DPPH radical-scavenging activity (EC₅₀: 176 μM) .

HY-W018643A

(E)-Ferulic acid methyl ester Methyl (E)-ferulate	COX	Others
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) exhibits strong DPPH and ABTS ⁺ radical scavenging activities .

HY-N15703

Norisocorydine (+)-Norisocorydine	Others	Neurological Disease
Norisocorydine ((+)-Norisocorydine) is an aporphine alkaloid with antinociceptive and radical scavenging effects. Norisocorydine shows a SC₅₀ of 14.1 μg/mL in DPPH radical scavenging test. Norisocorydine exhibits antinociceptive ability in mice .

HY-N3858

Erythristemine	Others	Inflammation/Immunology
Erythristemine is an alkaloid that can be isolated from Erythrina lysistemon. Erythristemine has weak DPPH radical scavenging properties .

HY-N11895

Isorabaichromone	Reactive Oxygen Species (ROS)	Inflammation/Immunology
Isorabaichromone is a potent antioxidant agent. Isorabaichromone shows a potent antioxidative activity and exhibits DPPH radical and superoxide anion scavenging activities .

HY-N6672

Caulophylline B	Others	Inflammation/Immunology
Caulophylline B is a fluorenone alkaloid isolated from the roots of Caulophyllum robustum Maxim, affords a low scavenging effect against DPPH radical .

HY-N7931

Regaloside A 1 Publications Verification	NO Synthase NF-κB	Inflammation/Immunology
Regaloside A, a phenylpropanoid, shows significant DPPH radical scavenging activity of 58.0% at 160 ppm. Regaloside A has anti-inflammatory activity .

HY-124496

Piperitenone	Mitochondrial Metabolism Reactive Oxygen Species (ROS)	Others
Piperitenone is a terpenoid, and exhibits antioxidant activity. Piperitenone scavenges DPPH free radicals with an IC₅₀ of 22.7 μg/mL, and inhibits the peroxidation of linoleic acid .

HY-N9368

Luteolin-7-O-α-L-arabinopyranosyl (1→6)-β-D-glucopyranoside	Others	Others
Luteolin-7-O-α-L-arabinopyranosyl (1→6)-β-D-glucopyranoside is a flavonoid with antiradical activity .

HY-N3349

Lyoniresinol	Others	Others
Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. Lyoniresinol has radical scavenging activities against DPPH with an IC₅₀ of 82.4 μM .

HY-N3349A

(-)-Lyoniresinol	Reactive Oxygen Species (ROS)	Others
(-)-Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. (-)-Lyoniresinol has radical scavenging activities against DPPH with an IC₅₀ of 82.4 μM .

HY-N8169

10-O-Trans-p-methoxycinnamoylcatalpol	Others	Others
10-O-Trans-p-methoxycinnamoylcatalpol has antioxidant activity with the IC₅₀ value of 0.37 μM/mL in DPPH free radical scavenging assay .

HY-W013677

4-Fluorobenzoic acid	Drug Intermediate	Infection
4-Fluorobenzoic acid is a drug intermediate that can be used to synthesize a series of hydrazone derivatives with antituberculosis activity and Schiff bases with DPPH radical scavenging activity .

HY-N9447

Norbergenin 1 Publications Verification	Reactive Oxygen Species (ROS)	Neurological Disease
Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC₅₀ 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging) .

Cat. No.	Product Name	Type

HY-D0168

Orcinol

3,5-Dihydroxytoluene

Dyes

Orcinol (3,5-Dihydroxytoluene) is an organic compound used in biological dyeing and proteomics research. Orcinol inhibits melanogenesis in B16F10 cells by upregulating the MAPK/ERK signaling pathway, and suppresses the expression of MITF, tyrosinase (TYR), TRP1, and DCT. Orcinol exhibits certain DPPH radical scavenging activity. In addition, Orcinol can alter nitrogen balance in animals. Orcinol holds promise for research in cancer and metabolic diseases .

Cat. No.	Product Name	Target	Research Area

HY-P1934A

Cyclo(L-Phe-L-Pro)	Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology Cancer
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-P5316

MHLWAAK	Peptides	Inflammation/Immunology
MHLWAAK is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK has high DPPH and ABTS radical scavenging ability. MHLWAAK protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5318

MDYYFEER	Reactive Oxygen Species (ROS)	Inflammation/Immunology
MDYYFEER is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER has high DPPH and ABTS radical scavenging ability. MDYYFEER protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5317

MAQAAEYYR	Reactive Oxygen Species (ROS)	Inflammation/Immunology
MAQAAEYYR is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5316A

MHLWAAK TFA	Peptides	Inflammation/Immunology
MHLWAAK TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK TFA has high DPPH and ABTS radical scavenging ability. MHLWAAK TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5318A

MDYYFEER TFA	Peptides	Inflammation/Immunology
MDYYFEER TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER TFA has high DPPH and ABTS radical scavenging ability. MDYYFEER TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .