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Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer . Gamma-Mangostin inhibits [3 H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes .
TD52, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 has less p-EGFR inhibition and has potent anti-cancer activity . TD52 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
TD52 dihydrochloride, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 dihydrochloride mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 dihydrochloride indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 dihydrochloride has less p-EGFR inhibition and has potent anti-cancer activity . TD52 (dihydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Anti-MRSA agent 31 (Compound 6) is an anti-methicillin-resistant Staphylococcus aureus (MRSA) agent with a MIC of 97 μg/mL and a MBC of 781.25 μg/mL. Anti-MRSA agent 31 has a potent antibacterial activity and a strong BindingProtein2a (PBP2a) inhibitory activity .
Gamma-Mangostin (Standard) is the analytical standard of Gamma-Mangostin. This product is intended for research and analytical applications. Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer . Gamma-Mangostin inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes .
Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer . Gamma-Mangostin inhibits [3 H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes .
Gamma-Mangostin (Standard) is the analytical standard of Gamma-Mangostin. This product is intended for research and analytical applications. Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer . Gamma-Mangostin inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes .
The S100A6 protein is a key calcium sensor that actively promotes cellular calcium signaling and is involved in multiple processes, including actin cytoskeletal reorganization and cell motility. As a homodimer binding two calcium ions, it interacts with TPR-containing proteins, CACYBP, ANXA2, ANXA11, SUGT1, tropomyosin, TP53, PPP5C, and TPPP. S100A6 Protein, Human (His) is the recombinant human-derived S100A6 protein, expressed by E. coli , with N-6*His labeled tag.
Peroxiredoxin-2 (PRDX2) is a thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides, which is essential for cellular protection against oxidative stress. It detoxifies peroxide, senses hydrogen peroxide-mediated signaling events, and may participate in signaling cascades initiated by growth factors and tumor necrosis factor-alpha. Peroxiredoxin-2/PRDX2 Protein, Human (His) is the recombinant human-derived Peroxiredoxin-2/PRDX2 protein, expressed by E. coli , with N-His labeled tag.
Phospho-p38 (Thr180+Tyr182) Antibody is a rabbit-derived non-conjugated IgG antibody, targeting Phospho-p38 (Thr180+Tyr182), with a predicted molecular weight of 41 kDa . Phospho-p38 (Thr180+Tyr182) Antibody can be used for WB, IHC-P, FC, ICC/IF, ELISA experiments in human, mouse backgrounds.
p38 Antibody (YA696) is a non-conjugated and Mouse origined monoclonal antibody about 41 kDa, targeting to p38 (5A1). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat, Monkey.
p38 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 41 kDa, targeting to p38. It can be used for WB,IP assays with tag free, in the background of Human.
9330148M11Rik; C80220; GTP BindingProtein; LHX; OTTMUSP00000004796; RAB2; RAB2 member RAS oncogene family; RAB2a; RAB2a, member RAS oncogene family; RAB2a_HUMAN; Ras related Protein Rab 2a; RAS-associated Protein RAB2; Ras-related Protein Rab-2a; RP23-183L6.1; Small GTP BindingProtein RAB2a.
WB, ICC
Human
Rab2 Antibody (YA5218) is a mouse-derived and non-conjugated monoclonal antibody, targeting to Rab2. It can be applicated for WB, ICC assays, in the background of human.
Mitogen-activated Protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-BindingProtein; CSAID-BindingProtein; CSBP; MAP kinase MXI2; MAX-interacting Protein 2; Mitogen-activated Protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated Protein kinase 2a; SAPK2a;
WB, ICC/IF, ELISA
Human, Mouse, Rat
p38 Antibody (YA5404) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to p38. It can be applicated for WB, ICC/IF, ELISA assays, in the background of human, mouse, rat.
Mitogen-activated Protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-BindingProtein; CSAID-BindingProtein; CSBP; MAP kinase MXI2; MAX-interacting Protein 2; Mitogen-activated Protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated Protein kinase 2a; SAPK2a;
WB, ICC/IF, IP, ELISA
Human, Mouse, Rat
p38 Antibody (YA6152) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p38. It can be applicated for WB, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.
Transcription factor AP2 alpha Antibody is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3441), targeting Transcription factor AP2 alpha, with a predicted molecular weight of 48 kDa (observed band size: 48 kDa). Transcription factor AP2 alpha Antibody (YA3441) can be used for WB, IF-Cell, IHC-P experiment in human, Mouse, Rat background.
AV026640; BCH; Benign chorea; BHC; Homeobox Protein NK 2 homolog A; Homeobox Protein NK-2 homolog A; Homeobox Protein Nkx 2.1; Homeobox Protein Nkx-2.1; Homeobox Protein Nkx2.1; NK 2; NK 2 homolog A; NK2; NK2 homeobox 1; NK2, drosophila, homolog of, A; NK2.1, Mouse, homolog of; Nkx 2 1; NKX 2.1; NKX 2a; NKX2 1; Nkx2-1; NKX2.1; NKX21_HUMAN; NKX2a; T EBP; T/EBP; TEBP; Thyroid nuclear factor 1; Thyroid nuclear factor; Thyroid specific enhancer BindingProtein; Thyroid transcription factor 1; Tin man; Tinman; TITF 1; TITF1; TTF 1; TTF-1; TTF1
IHC-P, WB, ICC/IF, ELISA
Human, Mouse, Rat
TTF-1 Antibody (YA5637) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TTF-1. It can be applicated for IHC-P, WB, ICC/IF, ELISA assays, in the background of human, mouse, rat.
AV026640; BCH; Benign chorea; BHC; Homeobox Protein NK 2 homolog A; Homeobox Protein NK-2 homolog A; Homeobox Protein Nkx 2.1; Homeobox Protein Nkx-2.1; Homeobox Protein Nkx2.1; NK 2; NK 2 homolog A; NK2; NK2 homeobox 1; NK2, drosophila, homolog of, A; NK2.1, Mouse, homolog of; Nkx 2 1; NKX 2.1; NKX 2a; NKX2 1; Nkx2-1; NKX2.1; NKX21_HUMAN; NKX2a; T EBP; T/EBP; TEBP; Thyroid nuclear factor 1; Thyroid nuclear factor; Thyroid specific enhancer BindingProtein; Thyroid transcription factor 1; Tin man; Tinman; TITF 1; TITF1; TTF 1; TTF-1; TTF1
WB, IHC-P, ICC/IF, IP, ELISA
Human, Mouse, Rat
TTF1 Antibody (YA5847) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TTF1. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.
TCF3; BHLHB21; E2a; ITF1; Transcription factor E2-alpha; Class B basic helix-loop-helix Protein 21; bHLHb21; Immunoglobulin enhancer-Binding factor E12/E47; Immunoglobulin transcription factor 1; Kappa-E2-Binding factor; Transcription facto
WB, FC, ELISA
Human
E2A Antibody (YA4819) is a mouse-derived and non-conjugated monoclonal antibody, targeting to E2A. It can be applicated for WB, FC, ELISA assays, in the background of human.
Phospho-p38 (Thr180/Tyr182) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 41 kDa, targeting to Phospho-p38 (Thr180/Tyr182). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.
TCF3 / E2A Antibody (YA1220) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1220), targeting TCF3 / E2A. TCF3 / E2A Antibody (YA1220) can be used for IHC-P experiment in human background.
RUNX2 Antibody (YA6091) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RUNX2. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.
ZEB1 Antibody (YA1153) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1153), targeting ZEB1. ZEB1 Antibody (YA1153) can be used for IHC-P experiment in human background.
TD52, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 has less p-EGFR inhibition and has potent anti-cancer activity . TD52 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
TD52 dihydrochloride, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 dihydrochloride mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 dihydrochloride indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 dihydrochloride has less p-EGFR inhibition and has potent anti-cancer activity . TD52 (dihydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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