1. Search Result
Search Result
Results for "

B10

" in MedChemExpress (MCE) Product Catalog:

31

Inhibitors & Agonists

6

Peptides

2

Inhibitory Antibodies

3

Natural
Products

16

Recombinant Proteins

1

Isotope-Labeled Compounds

7

Antibodies

8

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-44307

    Ferroptosis Cancer
    84-B10 is a 3-phenylglutaric acid derivative. 84-B10 inhibits cisplatin (HY-17394) induced tubular ferroptosis. 84-B10 attenuates cisplatin-induced mitochondrial damage and oxidative stress. 84-B10 ameliorates cisplatin-induced acute kidney injury (AKI) .
    84-B10
  • HY-145891

    Others Inflammation/Immunology
    B10-S is a potent anti-allergic agent. B10-S can inhibit the degranulation of LAD2 induced by substance P .
    B10-S
  • HY-159710

    Liposome Others
    TNT-b10 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). TNT-b10 is a carrier for both siRNA and mRNA .
    TNT-b10
  • HY-P2120

    Bacterial Others
    Pseudobactin A is a non-fluorescent extracellular iron carrier produced by the plant growth-promoting bacterium Pseudomonas B10 .
    Pseudobactin A
  • HY-125745

    Antibiotic Bacterial Infection
    Loloatin B 10 is an antibiotic, which exhibits antibacterial efficacy against gram positive antibiotic resistant human pathogens .
    Loloatin B 10
  • HY-172835

    JH-B10

    HBV Infection
    Rapavir (JH-B10) is a selective and potent sodium taurocholate cotransporting polypeptide (NTCP) inhibitor with an IC50 value of 1.8 nM for the uptake of taurocholic acid-d4 (TCA-d4). Rapavir exerts antiviral activity by directly binding to NTCP and blocking the entry of the virus into cells during the HBV infection phase. Rapavir is promising for research of HBV infections .
    Rapavir
  • HY-145643

    ZRC3308-B10

    SARS-CoV Infection
    Nepuvibart (ZRC3308-B10) is an anti-SARS-CoV-2 monoclonal antibody (IgG1 type). Nepuvibart shows good binding affinity to a non-competing epitope on the RBD of the SARS-CoV-2 spike protein. Nepuvibart can be used in combination with ZRC3308-A7 (HY-145642) at a ratio of 1:1, which is effective for the prevention of COVID-19 and the early stage of COVID-19 before the development of severe disease .
    Nepuvibart
  • HY-172920

    Wnt β-catenin Inflammation/Immunology Cancer
    Wnt/β-catenin-IN-6 (compound B10) is a potent Wnt/β-catenin pathway inhibitor. Wnt/β-catenin-IN-6 inhibits A549 cells activity with an IC50 of 1.28 μM .
    Wnt/β-catenin-IN-6
  • HY-P1089

    PCC 88-104

    Cytochrome P450 Inflammation/Immunology
    Cytochrome c-pigeon (88-104) (PCC 88-104) has full stimulatory activity for pigeon cytochrome c-primed T cells from B10.A mice. The I-E k-restricted T cell response to Cytochrome c pigeon (pcyt c) is specific for the COOH-terminal sequence 88-104 .
    Cytochrome c-pigeon (88-104)
  • HY-145642

    ZRC3308-A7

    SARS-CoV Infection
    Masavibart (ZRC3308-A7) is an anti-SARS-CoV-2 monoclonal antibody (IgG1 type). Masavibart shows good binding affinity to a non-competing epitope on the RBD of the SARS-CoV-2 spike protein. Masavibart can be used in combination with ZRC3308-B10 (HY-145643) at a ratio of 1:1, which is effective for the prevention of COVID-19 and the early stage of COVID-19 before the development of severe disease .
    Masavibart
  • HY-152671

    Monoamine Oxidase Neurological Disease
    hMAO-B-IN-4 (compound B10) is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value and a Ki value of 0.067 and 0.03 μM, respectively. hMAO-B-IN-4 inhibits hMAO-A with an IC50 value of 33.82 μM. hMAO-B-IN-4 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research .
    hMAO-B-IN-4
  • HY-146408

    Anaplastic lymphoma kinase (ALK) Cancer
    ALK-IN-21 (Compound B10), a potent ALK inhibitor for ALKG1202R mutation, exhibits remarkable enzymatic inhibitory potency with IC50 values of 4.59 nM, 2.07 nM and 5.95 nM toward ALK WT, ALK L1196M and ALK G1202R, respectively. ALK-IN-21 efficiently inhibits the proliferation of ALK-positive Karpas299 and H2228 cells both with IC50 values of 0.07 μM. ALK-IN-21 can be used for the research of anaplastic large cell lymphoma .
    ALK-IN-21
  • HY-139696

    Aldose Reductase Cancer
    AKR1B10-IN-1 is a potent inhibitor of AKR1B10 (Aldo-Keto Reductase 1B10) with an IC50 of 3.5 nM. AKR1B10-IN-1 suppresses proliferation, metastasis, and Cisplatin (CDDP) resistance of lung cancer cells .
    AKR1B10-IN-1
  • HY-104047
    LM22B-10
    Maximum Cited Publications
    19 Publications Verification

    Trk Receptor Akt ERK Neurological Disease
    LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor, and can induce TrkB, TrkC, AKT and ERK activation in vitro and in vivo.
    LM22B-10
  • HY-RS15437

    Small Interfering RNA (siRNA) Others

    UGT2B10 Human Pre-designed siRNA Set A contains three designed siRNAs for UGT2B10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    UGT2B10 Human Pre-designed siRNA Set A
    UGT2B10 Human Pre-designed siRNA Set A
  • HY-RS00533

    Small Interfering RNA (siRNA) Others

    AKR1B10 Human Pre-designed siRNA Set A contains three designed siRNAs for AKR1B10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    AKR1B10 Human Pre-designed siRNA Set A
    AKR1B10 Human Pre-designed siRNA Set A
  • HY-RS06390

    Small Interfering RNA (siRNA) Others

    HSD17B10 Human Pre-designed siRNA Set A contains three designed siRNAs for HSD17B10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    HSD17B10 Human Pre-designed siRNA Set A
    HSD17B10 Human Pre-designed siRNA Set A
  • HY-RS23692

    Small Interfering RNA (siRNA) Others

    Akr1b10 Rat Pre-designed siRNA Set A contains three designed siRNAs for Akr1b10 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Akr1b10 Rat Pre-designed siRNA Set A
    Akr1b10 Rat Pre-designed siRNA Set A
  • HY-RS17238

    Small Interfering RNA (siRNA) Others

    Akr1b10 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Akr1b10 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Akr1b10 Mouse Pre-designed siRNA Set A
    Akr1b10 Mouse Pre-designed siRNA Set A
  • HY-P10687

    RXFP Receptor Others
    H3B10-27(13/17αF) is an excellent scaffold for further developing reagent candidates and an important tool for understanding the physiological functions of the neuropeptide G protein-coupled receptor RXFP3, and it's very stable in serum .
    H3B10-27(13/17αF)
  • HY-N8266

    10-Deacetyltaxol B

    Others Others
    10-Deacetylcephalomannine is a taxane that can be isolated from the bark of Taxus baccata L. .
    10-Deacetylcephalomannine
  • HY-N1144

    Normacusine B; 10-Deoxysarpagine; Vellosiminol

    Others Others
    Tombozine (Normacusine B) is a Sesquiterpenoids product that can be isolated from the leaves of Alpinia intermedia .
    Tombozine
  • HY-122177

    Aldose Reductase Cancer
    MK181 is an aldose reductase (AR) inhibitor with IC50s of 0.71 μM and 4.5 μM for aldose reductase and AKR1B10, respectively. MK181 can bind into the external loop A subpocket of AKR1B10 .
    MK181
  • HY-105185
    Fidarestat
    3 Publications Verification

    SNK 860

    Aldose Reductase Metabolic Disease
    Fidarestat (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease.
    Fidarestat
  • HY-RS04389

    Small Interfering RNA (siRNA) Others

    ENPP3 Human Pre-designed siRNA Set A contains three designed siRNAs for ENPP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ENPP3 Human Pre-designed siRNA Set A
    ENPP3 Human Pre-designed siRNA Set A
  • HY-RS24067

    Small Interfering RNA (siRNA) Others

    Enpp3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Enpp3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Enpp3 Rat Pre-designed siRNA Set A
    Enpp3 Rat Pre-designed siRNA Set A
  • HY-W107409

    Others Cancer
    Meridianin C is a marine natural product with anticancer activity. Meridianin C has significant inhibitory effects on four different human tongue cancer cells (YD-8, YD-10B, YD-38 and HSC-3). Meridianin C most strongly reduced the growth of YD-10B cells, the most aggressive and tumorigenic of the cell lines tested. Meridianin C also induced significant accumulation of large vesicles in YD-10B cells, validating its function through macrophagocytosis. Meridianin C reduces cellular levels of Dickkopf-related protein-3 (DKK-3), a known negative regulator of macrophagy. Meridianin C affects macrophagocytosis by downregulating DKK-3, thereby affecting cell proliferation .
    Meridianin C
  • HY-50751
    Linifanib
    5 Publications Verification

    ABT-869; AL-39324

    PDGFR VEGFR FLT3 c-Fms c-Kit Autophagy Apoptosis Cancer
    Linifanib (ABT-869) is a potent and orally active multi-target inhibitor of VEGFR and PDGFR family with IC50s of 4, 3, 66, and 4 nM for KDR, FLT1, PDGFRβ, and FLT3, respectively. Linifanib shows prominent antitumor activity. Linifanib has much less activity against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. Linifanib is a specific miR-10b inhibitor that blocks miR-10b biogenesis .
    Linifanib
  • HY-50751R

    PDGFR VEGFR FLT3 c-Fms c-Kit Autophagy Apoptosis Cancer
    Linifanib (Standard) is the analytical standard of Linifanib. This product is intended for research and analytical applications. Linifanib (ABT-869) is a potent and orally active multi-target inhibitor of VEGFR and PDGFR family with IC50s of 4, 3, 66, and 4 nM for KDR, FLT1, PDGFRβ, and FLT3, respectively. Linifanib shows prominent antitumor activity. Linifanib has much less activity against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. Linifanib is a specific miR-10b inhibitor that blocks miR-10b biogenesis .
    Linifanib (Standard)
  • HY-168526

    Keap1-Nrf2 Inflammation/Immunology
    Keap1-Nrf2-IN-24 (compound 57) is a potent Keap1-Nrf2 inhibitor with a Ki value of 13 nM. Keap1-Nrf2-IN-24 increases the protein expression of TRXR1 and NQO1. Keap1-Nrf2-IN-24 increases the AKR1B10 mRNA expression. Keap1-Nrf2-IN-24 shows good metabolic stability .
    Keap1-Nrf2-IN-24
  • HY-W741425

    Isotope-Labeled Compounds Others
    21-O-Acetyl dexamethasone 9,11-epoxide-d5 is the deuterium labeled 2-((4aS,4bS,5aS,6aS,7R,8R,9aS,9bS)-7-Hydroxy-4a,6a,8-trimethyl-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)-2-oxoethyl acetate (Dexamethasone Acetate Impurity) (HY-Z8003).
    21-O-Acetyl dexamethasone 9,11-epoxide-d5

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: