Heme Oxygenase 1 Antibody (YA3727)

Heme Oxygenase 1 Antibody (YA3727) is a mouse-derived and non-conjugated IgG1 antibody, targeting to HMOX1. It can be applicated for IHC-P, FC, ELISA assays, in the background of human.

HO-1 protein, through its catalytic activity, orchestrates the oxidative cleavage of heme at the alpha-methene bridge carbon, leading to the release of carbon monoxide (CO) and the generation of biliverdin IXalpha. Simultaneously, it liberates the central heme iron chelate as ferrous iron. This enzymatic process not only provides a mechanism for the breakdown of heme but also exerts a cytoprotective effect by preventing the sensitization of cells to programmed cell death or apoptosis. The ability of HO-1 to catabolize free heme underscores its crucial role in cellular defense mechanisms, contributing to cell survival and protection against various stressors.

P09601

Predicted band size: 33 kDa; Observed band size: 33 kDa

affinity purified.

Non-conjugated

Primary Antibody; Mouse Monoclonal Antibody

Mouse

Human

IHC: 1/200-1/1000; FC: 1/200-1/400; ELISA: 1/10000

IHC-P, FC, ELISA

Liquid

Supplied in PBS with 0.05% sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Purified recombinant fragment of human HMOX1 (AA: 1-110) expressed in E. Coli.