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Aryl Hydrocarbon Receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aryl Hydrocarbon Receptor (108) 5-HT Receptor (1) Adenosine Receptor (3) Androgen Receptor (7) Apoptosis (7) Autophagy (4) Bacterial (2) Biochemical Assay Reagents (3) CDK (1) Checkpoint Kinase (Chk) (1) Collagen (3) Cytochrome P450 (13) E1/E2/E3 Enzyme (2) Endogenous Metabolite (19) Epigenetic Reader Domain (1) ERK (2) Estrogen Receptor/ERR (4) Ferroptosis (2) Fungal (9) GLUT (2) Glycosidase (2) GSK-3 (1) HBV (1) HIF/HIF Prolyl-Hydroxylase (3) Isotope-Labeled Compounds (10) LXR (2) MDM-2/p53 (2) MEK (2) Na+/K+ ATPase (1) NF-κB (2) p38 MAPK (4) PARP (1) PERK (4) PPAR (1) PROTACs (1) Pyroptosis (2) Reactive Oxygen Species (ROS) (3) Reference Standards (16) ROR (1) VD/VDR (2) VEGFR (1) β-glucuronidase (1)
By Research Areas:	Cancer (64) Cardiovascular Disease (7) Endocrinology (7) Infection (7) Inflammation/Immunology (37) Metabolic Disease (11) Neurological Disease (15)
Click Chemistry:	Alkynes (1)

122

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

MeBIO	Aryl Hydrocarbon Receptor GSK-3 CDK	Others
MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist, with IC₅₀ of 44 μM (GSK-3) and 55 μM (CDK1/cyclin B), respectively .

Skatole 5+ Cited Publications 3-Methylindole; 3-Methyl-1H-indole	Aryl Hydrocarbon Receptor p38 MAPK Endogenous Metabolite Apoptosis	Others
Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream .

Skatole (Standard) 3-Methylindole (Standard); 3-Methyl-1H-indole (Standard)	Reference Standards Aryl Hydrocarbon Receptor p38 MAPK Endogenous Metabolite Apoptosis	Others
Skatole (Standard) is the analytical standard of Skatole. This product is intended for research and analytical applications. Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream .

BAY-218 1 Publications Verification AHR antagonist 1	Aryl Hydrocarbon Receptor	Inflammation/Immunology Cancer
BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC₅₀ of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses .

FICZ 20+ Cited Publications 6-Formylindolo[3,2-b]carbazole	Aryl Hydrocarbon Receptor	Others
FICZ is a potent aryl hydrocarbon receptor (AhR) agonist with a K_d of 70 pM.

AHR-IN-1	Aryl Hydrocarbon Receptor	Cancer
AHR-IN-1 (1-103) is an aryl hydrocarbon receptor (AHR) inhibitor with IC₅₀ < 0.5 μM .

L-Kynurenine sulfate	Endogenous Metabolite Aryl Hydrocarbon Receptor	Inflammation/Immunology
L-Kynurenine sulfate, an **aryl hydrocarbon receptor (AHR**) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype .

AhR agonist 8	Aryl Hydrocarbon Receptor	Inflammation/Immunology
AhR agonist 8 (compound 9) is a potent Aryl Hydrocarbon Receptor (AhR) agonist with an EC₅₀ of 0.154 nM. AhR agonist 8 can be used in the study of psoriasis and atopic dermatitis .

Stemregenin 1 10+ Cited Publications SR1	Aryl Hydrocarbon Receptor	Cancer
Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with IC₅₀ of 127 nM.

CHD-5	Aryl Hydrocarbon Receptor	Others
CHD-5 is a potent AhR (aryl hydrocarbon receptor) antagonist .

Mivotilate 2 Publications Verification YH439	Aryl Hydrocarbon Receptor	Others
Mivotilate is a nontoxic, potent activator of the aryl hydrocarbon receptor (AhR), and acts as a hepatoprotective agent.

L-Kynurenine 15+ Cited Publications	Aryl Hydrocarbon Receptor Endogenous Metabolite	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an **aryl hydrocarbon receptor** agonist.

Diosmin 10+ Cited Publications	Aryl Hydrocarbon Receptor	Cardiovascular Disease Cancer
Diosmin is a flavonoid found in a variety of citrus fruits and also an agonist of the **aryl hydrocarbon receptor (AhR**).

1,4-Chrysenequinone Chrysene-1,4-dione	Aryl Hydrocarbon Receptor	Cancer
1,4-Chrysenequinone, a polycyclic aromatic quinone, acts as an activator of aryl hydrocarbon receptor (AhR).

PDM2 3 Publications Verification	Aryl Hydrocarbon Receptor	Inflammation/Immunology
PDM2 is a selective, high-affinity aryl hydrocarbon receptor (AhR) antagonist with an K_i of 1.2±0.4 nM.

AhR agonist 6	Aryl Hydrocarbon Receptor	Inflammation/Immunology
AhR agonist 6 (Compound 6) is an agonist for aryl hydrocarbon receptor (AhR), with an EC₅₀ of 0.01 nM .

AHR antagonist 6	Aryl Hydrocarbon Receptor	Cancer
AHR antagonist 6 (Compound 44) is an aryl hydrocarbon receptor (AHR) antagonist used in cancer research .

Glucoerucin potassium	Aryl Hydrocarbon Receptor	Others
Glucoerucin potassium is an **aryl hydrocarbon receptor** antagonist and is the 4-methylthio-butyl glucosinolate found in the seeds of Eruca sativa Mill .

Glucoerucin	Endogenous Metabolite Aryl Hydrocarbon Receptor	Others
Glucoerucin is an **aryl hydrocarbon receptor** antagonist and is the 4-methylthio-butyl glucosinolate found in the seeds of Eruca sativa Mill .

ITE 5+ Cited Publications	Aryl Hydrocarbon Receptor	Inflammation/Immunology Cancer
ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), binding directly to AHR, with a K_i of 3 nM. ITE also has immunosuppressive activity.

Tapinarof 5+ Cited Publications WBI-1001; Benvitimod; GSK2894512	Aryl Hydrocarbon Receptor	Inflammation/Immunology
Tapinarof (WBI-1001) is a natural **aryl hydrocarbon receptor (AhR) agonist with an EC₅₀** of 13 nM. Tapinarof resolves skin inflammation in mice .

CAY10464 AHR antagonist 7	Aryl Hydrocarbon Receptor	Cancer
CAY10464 (AHR antagonist 7; compound 4j) is a selective and high-affinity aryl hydrocarbon receptor (AhR) antagonist with a K_i of 1.4 nM .

Mivotilate (Standard) YH439 (Standard)	Reference Standards Aryl Hydrocarbon Receptor	Others
Mivotilate (Standard) is the analytical standard of Mivotilate. This product is intended for research and analytical applications. Mivotilate is a nontoxic, potent activator of the aryl hydrocarbon receptor (AhR), and acts as a hepatoprotective agent.

6,2',4'-Trimethoxyflavone	Aryl Hydrocarbon Receptor	Neurological Disease Cancer
6,2',4'-Trimethoxyflavone is a potent aryl hydrocarbon receptor (AHR) antagonist. 6,2',4'-Trimethoxyflavone represses AHR-mediated gene induction .

Stemregenin 1 (Standard)	Aryl Hydrocarbon Receptor	Cancer
Stemregenin 1 (Standard) is the analytical standard of Stemregenin 1. This product is intended for research and analytical applications. Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with IC50 of 127 nM.

Diosmin (Standard)	Reference Standards Aryl Hydrocarbon Receptor	Cardiovascular Disease Cancer
Diosmin (Standard) is the analytical standard of Diosmin. This product is intended for research and analytical applications. Diosmin is a flavonoid found in a variety of citrus fruits and also an agonist of the aryl hydrocarbon receptor (AhR).

1-Hydroxypyrene	Aryl Hydrocarbon Receptor Cytochrome P450 Collagen	Inflammation/Immunology
1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes. 1-Hydroxypyrene is the orally active agonist for **aryl hydrocarbon receptor (AhR**) and can lead to renal fibrosis .

Pifithrin-α hydrobromide 70+ Cited Publications Pifithrin hydrobromide; PFTα hydrobromide	MDM-2/p53 Aryl Hydrocarbon Receptor Ferroptosis Apoptosis	Cancer
Pifithrin-α hydrobromide is a p53 inhibitor which blocks its transcriptional activity and prevents cells from apoptosis. Pifithrin-α hydrobromide is also an aryl hydrocarbon receptor (AhR) agonist.

L-Kynurenine (Standard) 15+ Cited Publications	Reference Standards Aryl Hydrocarbon Receptor Endogenous Metabolite	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Kynurenine (Standard) is the analytical standard of L-Kynurenine. This product is intended for research and analytical applications. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an **aryl hydrocarbon receptor** agonist.

Corannulene	Aryl Hydrocarbon Receptor	Cancer
Corannulene is an agonist of aryl hydrocarbon receptor (AhR). Corannulene causes less cytotoxic responses than Benzo[a]pyrene (HY-107377) in hepatoma cells. Corannulene is promising for research of cancers .

Indeno[1,2,3-cd]pyrene	Aryl Hydrocarbon Receptor	Inflammation/Immunology Cancer
Indeno[1,2,3-cd]pyrene is a polycyclic aromatic hydrocarbon with moderate cytotoxicity in human pulmonary alveolar epithelial cells HPAEpiC. Indeno[1,2,3-cd]pyrene enhances allergic lung infammation via aryl hydrocarbon receptor .

Norisoboldine hydrochloride (+)-Laurelliptine hydrochloride	Adenosine Receptor	Inflammation/Immunology
Norisoboldine hydrochloride is an orally active natural aryl hydrocarbon receptor (AhR) agonist. Norisoboldine hydrochloride, as a major isoquinoline alkaloid present in Radix Linderae, can be used for the research of Rheumatoid arthritis and Ulcerative colitis .

AFP464 dihydrochloride NSC710464 dihydrochloride	HIF/HIF Prolyl-Hydroxylase	Cancer
AFP464 (dihydrochloride) (NSC710464 (dihydrochloride)) is the hydrochloride form of AFP464 and is a potent HIF-1α inhibitor with an IC₅₀ value of 0.25 μM. It is also an activator of aryl hydrocarbon receptor (AhR).

Norisoboldine (+)-Laurelliptine	Adenosine Receptor	Inflammation/Immunology
Norisoboldine is an orally active natural aryl hydrocarbon receptor (AhR) agonist. Norisoboldine, as a major isoquinoline alkaloid present in Radix Linderae, can be used for the research of Rheumatoid arthritis and Ulcerative colitis .

AFP464 free base NSC710464 free base	HIF/HIF Prolyl-Hydroxylase	Cancer
AFP464 free base (NSC710464 free base), is an active HIF-1α inhibitor with an IC₅₀ of 0.25 μM, also is a potent aryl hydrocarbon receptor (AhR) activator.

GNF351 4 Publications Verification	Aryl Hydrocarbon Receptor	Others
GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with an IC₅₀ of 62 nM. GNF351 is minimal toxicity in mouse or human keratinocytes .

ITE (Standard)	Aryl Hydrocarbon Receptor	Inflammation/Immunology Cancer
ITE (Standard) is the analytical standard of ITE. This product is intended for research and analytical applications. ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), binding directly to AHR, with a Ki of 3 nM. ITE also has immunosuppressive activity.

Carbidopa monohydrate 1 Publications Verification (S)-(-)-Carbidopa monohydrate	Aryl Hydrocarbon Receptor	Neurological Disease Cancer
Carbidopa ((S)-(-)-Carbidopa) monohydrate, a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa monohydrate is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa monohydrate inhibits pancreatic cancer cell and tumor growth .

Cat. No.	Product Name	Type

HY-D0932

Sudan IV

Solvent Red 24; C.I. 26105

Dyes

Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections .

HY-15001G

Stemregenin 1 (GMP)

SR1 (GMP)

Fluorescent Dye

Stemregenin 1 (SR1) (GMP) is a GMP-grade Stemregenin 1 (HY-15001). GMP-grade small molecules can be used as adjuvants in cell therapy. Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with an IC₅₀ of 127 nM. Stemregenin 1 (GMP) can competitively bind to AhR and inhibit its nuclear translocation, inhibiting osteoclastogenesis and promoting hematopoietic progenitor cell expansion by blocking the AhR-c-src-NF-κB/p-ERK MAPK-NFATc1 signaling pathway. Stemregenin 1 (GMP) can be used for the treatment of osteoporosis, in vitro expansion of hematopoietic stem cells, and the study of the mechanism of bone metabolic diseases .

HY-D0932R

Sudan IV (Standard)

Solvent Red 24 (Standard); C.I. 26105 (Standard)

Dyes

Sudan IV (Standard) (Solvent Red 24 (Standard)) is the analytical standard of Sudan IV (HY-D0932). This product is intended for research and analytical applications. Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections.

Cat. No.	Product Name	Type

HY-15001G

Stemregenin 1 (GMP)

SR1 (GMP)

Biochemical Assay Reagents

Species:	Human (3)
Tag:	His (2) Tag Free (1) Strep (1)
Source:	Sf9 insect cells (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P704187

	AHR Protein, Human (His) Aryl Hydrocarbon Receptor; Ah Receptor; lass E basic helix-loop-helix protein 76 (bHLHe76); AHR; BHLHE76	Human	E. coli
	AHR Protein, Human (His) is the recombinant human-derived AHR protein, expressed by E. coli, with N-10*His tag.

HY-P701572

	IVNS1ABP Protein, Human (sf9) IVNS1ABP; Influenza virus NS1A-binding protein; NS1-BP; NS1-binding protein; Aryl Hydrocarbon Receptor-associated protein 3; Kelch-like protein 39	Human	Sf9 insect cells
	The IVNS1ABP protein is intricately involved in multiple cellular functions, including pre-mRNA splicing, aryl hydrocarbon receptor (AHR) pathway, F-actin organization, and protein ubiquitination. It binds to F-actin through Kelch repeats, thereby stabilizing actin filaments and thereby protecting cells from actin instability-induced cell death. IVNS1ABP Protein, Human (sf9) is the recombinant human-derived IVNS1ABP protein, expressed by sf9 insect cells , with tag free.

HY-P701573

	IVNS1ABP Protein, Human (sf9, His, StrepⅡ) IVNS1ABP; Influenza virus NS1A-binding protein; NS1-BP; NS1-binding protein; Aryl Hydrocarbon Receptor-associated protein 3; Kelch-like protein 39	Human	Sf9 insect cells
	The IVNS1ABP protein is intricately involved in multiple cellular functions, including pre-mRNA splicing, aryl hydrocarbon receptor (AHR) pathway, F-actin organization, and protein ubiquitination. It binds to F-actin through Kelch repeats, thereby stabilizing actin filaments and thereby protecting cells from actin instability-induced cell death. IVNS1ABP Protein, Human (sf9, His, Strep) is the recombinant human-derived IVNS1ABP protein, expressed by sf9 insect cells , with N-Strep, N-8*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-104026CS

L-Kynurenine-13C10 sulfate hemihydrate
L-Kynurenine- ¹³C10 (sulfate hemihydrate) is the ¹³C labeled L-Kynurenine sulfate. L-Kynurenine sulfate hemihydrate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype .

HY-104026S

L-Kynurenine-d4
L-Kynurenine-d₄ is the deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist[1][2].

HY-W007355S1

Skatole-d8
Skatole-d₈ is the deuterium labeled Skatole. Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38 .

HY-W007355S

Skatole-d3
Skatole-d₃ is the deuterium labeled Skatole. Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38 .

HY-104026S2

L-Kynurenine-d4-1 hydrochloride
L-Kynurenine-d₄-1 hydrochloride is the deuterium labeled L-Kynurenine (HY-104026). L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an **aryl hydrocarbon receptor** agonist .

HY-104026BS

L-Kynurenine-13C10 sulfate
L-Kynurenine-13C10 (sulfate) is the 13C labeled L-Kynurenine sulfate. L-Kynurenine sulfate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype .

HY-104026S1

L-Kynurenine-d4-1
L-Kynurenine-d₄-1 is deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

HY-104026S5

L-Kynurenine-13C10 sulfate hydrate
L-Kynurenine-13C10 sulfate hydrate is the C13 labeled L-Kynurenine sulfate hydrate. L-Kynurenine is an aryl hydrocarbon receptor agonist .

HY-109044S

Tapinarof-d5
Tapinarof-d₅ (WBI-1001-d₅) is deuterium labeled Tapinarof. Tapinarof (WBI-1001) is a natural **aryl hydrocarbon receptor (AhR) agonist with an EC₅₀** of 13 nM. Tapinarof resolves skin inflammation in mice .

HY-104026S3

L-Kynurenine-13C4,15N-1
L-Kynurenine- ¹³C₄, ¹⁵N-1 is the ¹³C and ¹⁵N labled L-Kynurenine (HY-104026) . L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an **aryl hydrocarbon receptor** agonist.

HY-B0311AS

Carbidopa-d3 monohydrate
Carbidopa-d₃ (monohydrate) is the deuterium labeled Carbidopa monohydrate. Carbidopa ((S)-(-)-Carbidopa) monohydrate, a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa monohydrate is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa monohydrate inhibits pancreatic cancer cell and tumor growth .

HY-W014075S

1-Hydroxypyrene-d9
1-Hydroxypyrene-d₉ is the deuterium labeled 1-Hydroxypyrene (HY-W014075). 1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes. 1-Hydroxypyrene is the orally active agonist for **aryl hydrocarbon receptor (AhR**) and can lead to renal fibrosis .

HY-B0311S1

Carbidopa-d3-1
Carbidopa-d3-1 is the deuterium labeled Carbidopa (HY-B0311). Carbidopa, a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa inhibits pancreatic cancer cell and tumor growth .

HY-W716464

Prochloraz-d7
Prochloraz-d₇ (BTS 40542-d₇) is the deuterium labeled Prochloraz (HY-B0845). Prochloraz is an imidazole antifungal. Prochloraz is as an estrogen receptor (ER) and androgen receptor (AR) antagonist and an aromatase inhibitor with IC₅₀ values of 25 μM, 4 μM and 0.3 μM, respectively. Prochloraz is able to activate the aryl hydrocarbon receptor (AhR) having an EC₅₀ of 1 μM .

HY-116214S

Cyprodinil-d5

Cyprodinil-d₅(CGA-219417-d₅) is the deuterium labeled Cyprodinil (HY-116214). Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens .

HY-116214S1

Cyprodinil-13C6

Cyprodinil- ¹³C₆ (CGA-219417- ¹³C₆) is the ¹³C₆ labeled Cyprodinil (HY-116214). Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens .

HY-W011338S

Benzyl butyl phthalate-d4

Benzyl butyl phthalate-d₄ is the deuterium labeled Benzyl butyl phthalate . Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) .

HY-D0932S

Sudan IV-d6

Sudan IV-d₆ (Solvent Red 24-d₆) is the deuterium labeled Sudan IV(HY-D0932). Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80378

	AHR Antibody (YA610) Ah Receptor; Aromatic Hydrocarbon Receptor; Aryl Hydrocarbon Receptor; Aryl Hydrocarbon Receptor precursor; BHLHE76; Class E basic helix loop helix protein 76; HGNC:348; AHR_HUMAN.	WB, ICC/IF	Human
	Aryl hydrocarbon Receptor Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 96 kDa, targeting to Aryl hydrocarbon Receptor. It can be used for WB,ICC/IF assays with tag free, in the background of Human.

HY-P80705

	HIF1 beta Antibody (YA385) ARNT; BHLHE2; Aryl Hydrocarbon Receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin Receptor; nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta	WB, IHC-P	Human, Mouse, Rat, Hamster
	HIF1 beta Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 87 kDa, targeting to HIF1 beta. It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat, Hamster.

HY-P82417

	Aryl Hydrocarbon Receptor Antibody (YA2162) Ah Receptor; AhR; Class E basic helix-loop-helix protein 76; bHLHe76; AHR	WB	Human
	Aryl Hydrocarbon Receptor Antibody (YA2162) is a non-conjugated IgG antibody, targeting Aryl Hydrocarbon Receptor, with a predicted molecular weight of 96 kDa (observed band size: 100 kDa). Aryl Hydrocarbon Receptor Antibody (YA2162) can be used for WB experiment in human background.

HY-P85750

	HIF-1β Antibody (YA5442) ARNT; BHLHE2; Aryl Hydrocarbon Receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin Receptor, nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	HIF-1β Antibody (YA5442) is a mouse-derived and non-conjugated monoclonal antibody, targeting to HIF-1β. It can be applicated for WB, IHC-P, ICC/IF assays, in the background of human, mouse, rat.

HY-P85059

	BMAL1 Antibody (YA4751) ARNTL; BHLHE5; BMAL1; MOP3; PASD3; Aryl Hydrocarbon Receptor nuclear translocator-like protein 1; Basic-helix-loop-helix-PAS protein MOP3; Brain and muscle ARNT-like 1; Class E basic helix-loop-helix protein 5; bHLHe5; Member of PAS protein	WB, IHC-P, ICC/IF, ELISA	Human
	BMAL1 Antibody (YA4751) is a mouse-derived and non-conjugated monoclonal antibody, targeting to BMAL1. It can be applicated for WB, IHC-P, ICC/IF, ELISA assays, in the background of human.

HY-P86191

	BMAL1 Antibody (YA5883) ARNTL; BHLHE5; BMAL1; MOP3; PASD3; Aryl Hydrocarbon Receptor nuclear translocator-like protein 1; Basic-helix-loop-helix-PAS protein MOP3; Brain and muscle ARNT-like 1Class E basic helix-loop-helix protein 5; bHLHe5; Member of PAS protein 3; PAS domain-containing protein 3; bHLH-PAS protein JAP3	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	BMAL1 Antibody (YA5883) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to BMAL1. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

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Cat. No.	Product Name		Classification

HY-155505

AHR agonist 4		Alkynes
AHR agonist 4 (compound 24e) is an agonist of **Aryl hydrocarbon receptor (AHR**), assocaited with the immune balance of Th17/22 and Treg cells. AHR agonist 4 serves as a lead compound for anti-psoriasis drug, alleviates imiquimod (IMQ)-induced psoriasis-like skin lesion . AHR agonist 4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Aryl Hydrocarbon Receptor

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

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