2. MAPK/ERK Pathway Stem Cell/Wnt Immunology/Inflammation Autophagy
  3. MEK ERK Aryl Hydrocarbon Receptor Autophagy
  4. PD98059 (Standard)

PD98059 (Standard) is the analytical standard of PD98059. This product is intended for research and analytical applications. PD98059 is a potent and selective MEK inhibitor with an IC50 of 5 µM. PD98059 binds to the inactive form of MEK, thereby preventing the activation of MEK1 (IC50 of 2-7 µM) and MEK2 (IC50 of 50 µM) by upstream kinases. PD98059 is a ERK1/2 signaling inhibitor. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR), and suppresses TCDD binding (IC50 of 4 μM) and AHR transformation (IC50 of 1 μM). PD98059 also inhibits Mycobacterium bovis Bacillus CalmetteGuerin (BCG)-induced autophagy.

For research use only. We do not sell to patients.

PD98059 (Standard)

PD98059 (Standard) Chemical Structure

CAS No. : 167869-21-8

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100 mg Get quote 5 - 7 weeks 4 - 6 weeks 4 - 6 weeks
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O=C1C=C(OC2=CC=CC=C21)C3=CC=CC(OC)=C3N
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PD98059 (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

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Keywords:

PD98059 (Standard)167869-21-8MEKERKAryl Hydrocarbon ReceptorAutophagyMitogen-activated protein kinase kinaseMAPKKMAP2KExtracellular signal regulated kinasesAhRInhibitorinhibitorinhibit

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