3-OH-Kynurenamine dihydroiodide

Cat. No.: HY-W764758 Purity: 99.56%: Data Sheet
COA

SDS
Handling Instructions
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3-OH-Kynurenamine dihydroiodide is the dihydroiodide form of 3-OH-Kynurenamine (HY-156908). 3-OH-Kynurenamine dihydroiodide is an activator for aryl hydrocarbon receptor (AhR), and thus regulates the immune response. 3-OH-Kynurenamine dihydroiodide upregulates the expressions of Ido1 and Tgfb1, ameliorates the skin inflammation in psoriasis mouse model and kidney damage in nephrotoxic lupus mouse model.

For research use only. We do not sell to patients.

3-OH-Kynurenamine dihydroiodide Chemical Structure

CAS No. : 2155855-77-7

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Other Forms of 3-OH-Kynurenamine dihydroiodide:

3-OH-Kynurenamine Get quote

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Purity & Documentation
References
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Description

Molecular Weight

436.03

Formula

C₉H₁₄I₂N₂O₂

CAS No.

2155855-77-7

Appearance

Oil

Color

Brown to black

SMILES

O=C(C1=CC=CC(O)=C1N)CCN.[H]I.[H]I

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 20.83 mg/mL (47.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2934 mL	11.4671 mL	22.9342 mL
5 mM	0.4587 mL	2.2934 mL	4.5868 mL
10 mM	0.2293 mL	1.1467 mL	2.2934 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.56%

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Data Sheet (270 KB) SDS (393 KB)

COA (249 KB) HNMR (269 KB) LCMS (94 KB)

Handling Instructions (2659 KB)

References

[1]. Laura SANTAMBROGIO. Immunoregulatory role of 3-oh-kynurenamine and uses thereof. Patent, WO2019178013A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2934 mL	11.4671 mL	22.9342 mL	57.3355 mL
	5 mM	0.4587 mL	2.2934 mL	4.5868 mL	11.4671 mL
	10 mM	0.2293 mL	1.1467 mL	2.2934 mL	5.7336 mL
	15 mM	0.1529 mL	0.7645 mL	1.5289 mL	3.8224 mL
	20 mM	0.1147 mL	0.5734 mL	1.1467 mL	2.8668 mL
	25 mM	0.0917 mL	0.4587 mL	0.9174 mL	2.2934 mL
	30 mM	0.0764 mL	0.3822 mL	0.7645 mL	1.9112 mL
	40 mM	0.0573 mL	0.2867 mL	0.5734 mL	1.4334 mL