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Results for "

tracts

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (7) Adrenergic Receptor (8) Antibiotic (139) Antifolate (8) Apoptosis (10) Autophagy (4) Bacterial (162) Beta-lactamase (7) Biochemical Assay Reagents (6) Bombesin Receptor (1) Calcium Channel (8) Carbonic Anhydrase (1) Caspase (1) CFTR (1) Chloride Channel (1) Cholecystokinin Receptor (1) COX (2) DNA/RNA Synthesis (9) Dopamine Receptor (4) Drug Derivative (2) Drug Intermediate (1) Drug Metabolite (9) Endogenous Metabolite (15) Fluorescent Dye (3) Fungal (1) GCGR (3) Guanylate Cyclase (2) HDAC (1) Histamine Receptor (1) HIV (6) Influenza Virus (11) Isotope-Labeled Compounds (25) mAChR (12) Motilin Receptor (1) Neurokinin Receptor (1) Neuromedin U Receptor (NMUR) (1) Opioid Receptor (6) P2X Receptor (1) P2Y Receptor (1) Parasite (6) PD-1/PD-L1 (1) Penicillin-binding protein (PBP) (8) Phosphodiesterase (PDE) (4) Potassium Channel (2) PPAR (5) Prostaglandin Receptor (2) Radionuclide-Drug Conjugates (RDCs) (1) Reactive Oxygen Species (1) ROR (1) RSV (5) SARS-CoV (2) SGLT (1) SOD (3) Toll-like Receptor (TLR) (2) TOPK (4) Topoisomerase (2) TRP Channel (1) β-glucuronidase (3) γ-secretase (2)
By Research Areas:	Cancer (58) Cardiovascular Disease (3) Endocrinology (6) Infection (178) Inflammation/Immunology (37) Metabolic Disease (29) Neurological Disease (39)

By Targets:

5-HT Receptor (7)

Adrenergic Receptor (8)

Antibiotic (139)

Antifolate (8)

Apoptosis (10)

Autophagy (4)

Bacterial (162)

Beta-lactamase (7)

Biochemical Assay Reagents (6)

Bombesin Receptor (1)

Calcium Channel (8)

Carbonic Anhydrase (1)

Caspase (1)

CFTR (1)

Chloride Channel (1)

Cholecystokinin Receptor (1)

COX (2)

DNA/RNA Synthesis (9)

Dopamine Receptor (4)

Drug Derivative (2)

Drug Intermediate (1)

Drug Metabolite (9)

Endogenous Metabolite (15)

Fluorescent Dye (3)

Fungal (1)

GCGR (3)

Guanylate Cyclase (2)

HDAC (1)

Histamine Receptor (1)

HIV (6)

Influenza Virus (11)

Isotope-Labeled Compounds (25)

mAChR (12)

Motilin Receptor (1)

Neurokinin Receptor (1)

Neuromedin U Receptor (NMUR) (1)

Opioid Receptor (6)

P2X Receptor (1)

P2Y Receptor (1)

Parasite (6)

PD-1/PD-L1 (1)

Penicillin-binding protein (PBP) (8)

Phosphodiesterase (PDE) (4)

Potassium Channel (2)

PPAR (5)

Prostaglandin Receptor (2)

Radionuclide-Drug Conjugates (RDCs) (1)

Reactive Oxygen Species (1)

ROR (1)

RSV (5)

SARS-CoV (2)

SGLT (1)

SOD (3)

Toll-like Receptor (TLR) (2)

TOPK (4)

Topoisomerase (2)

TRP Channel (1)

β-glucuronidase (3)

γ-secretase (2)

By Research Areas:

Cancer (58)

Cardiovascular Disease (3)

Endocrinology (6)

Infection (178)

Inflammation/Immunology (37)

Metabolic Disease (29)

Neurological Disease (39)

291

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0395C

Sitafloxacin hydrate 5 Publications Verification DU6859a hydrate	Bacterial Antibiotic	Infection
Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections .

HY-B0395

Sitafloxacin 5 Publications Verification DU6859a	Bacterial Antibiotic	Infection
Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection .

HY-B1257

Cefmetazole sodium Sodium cefmetazole	Bacterial Antibiotic	Infection Cancer
Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .

HY-B1595

Cefmetazole CS 1170	Antibiotic Bacterial	Infection Cancer
Cefmetazole (CS 1170) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative and anaerobic bacteria. Cefmetazole binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .

HY-B0395B

Sitafloxacin monohydrate DU6859a monohydrate	Bacterial Antibiotic	Infection
Sitafloxacin (DU6859a) monohydrate is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin monohydrate shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin monohydrate can be used for the research of respiratory tract infection and urinary tract infection .

HY-B0395A

Sitafloxacin hydrochloride DU6859a hydrochloride	Antibiotic Bacterial	Infection
Sitafloxacin (DU6859a) hydrochloride is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin hydrochloride shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin hydrochloride can be used for the research of respiratory tract infection and urinary tract infection .

HY-B0395CR

Sitafloxacin hydrate (Standard) DU6859a hydrate (Standard)	Bacterial Antibiotic	Infection
Sitafloxacin (hydrate) (Standard) is the analytical standard of Sitafloxacin (hydrate). This product is intended for research and analytical applications. Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections .

HY-159104

Cinnamon bark oil, from Cinnamonum zeylanicum Blume Cinnamomum Cassia oil	Fungal	Infection
Cinnamon bark oil, from Cinnamonum zeylanicum Blume is a antifungal agent against fungi causing respiratory tract mycoses .

HY-B1257R

Cefmetazole (sodium) (Standard)	Bacterial Antibiotic	Infection Cancer
Cefmetazole (sodium) (Standard) is the analytical standard of Cefmetazole (sodium). This product is intended for research and analytical applications. Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .

HY-A0111A

Cefetamet sodium Ro15-8074/001; Deacetoxycefotaxime sodium	Antibiotic Bacterial	Infection
Cefetamet sodium is a cephalosporin antibiotic. Cefetamet sodium has the potential for the research of both upper and lower community-acquired respiratory tract infections .

HY-A0111

Cefetamet Ro 15-8074; Deacetoxycefotaxime	Antibiotic Bacterial	Infection
Cefetamet is a cephalosporin antibiotic. Cefetamet has the potential for the research of both upper and lower community-acquired respiratory tract infections .

HY-132987

Avibactam tomilopil 2 Publications Verification ARX-1796; AV-006	Beta-lactamase Bacterial Drug Intermediate	Infection
Avibactam tomilopil (ARX-1796, AV-006) is an orally active prodrug of Avibactam and a β-lactamase inhibitor. Avibactam tomilopil can be used in the study of diseases such as urinary tract infections .

HY-B0213

Sulfameter 2 Publications Verification Sulfametoxydiazine; 5-Methoxysulfadiazine	Antibiotic Bacterial	Infection
Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis .

HY-16472

Sulfacytine	Antibiotic Bacterial	Infection
Sulfacytine is a short-acting sulfonamide antibiotic. Sulfacytine is active against bacteria and is an effective agent for the research of acute uncomplicated urinary tract infections .

HY-108971

Demecycline	Antibiotic Bacterial	Infection
Demecycline, a tetracycline antibiotic, is the C6-demethylated derivative of Tetracycline (HY-A0107) against bacterial infections including pneumonia and other respiratory tract infections .

HY-108402AR

Cefodizime sodium (Standard)	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Cefodizime (sodium) (Standard) is the analytical standard of Cefodizime (sodium). This product is intended for research and analytical applications. Cefodizime sodium is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime sodium has no renal toxic effect, good tolerance and immune regulation activity, and can be used for the research of severe infections of the respiratory and urinary tracts[1][2].

HY-W009886

3,4,5-Trimethoxybenzaldehyde	Bacterial	Infection
3,4,5-Trimethoxybenzaldehyde is an intermediate for the synthesis of various pharmaceuticals, especially for trimethoprim used to research bacterial infections, including urinary tract pathogens infection.

HY-163773

RSV-IN-13	RSV	Infection
RSV-IN-13 (compound 5c) exhibits antiviral activity against RSV with an EC₅₀ value of 0.78 nM. RSV-IN-13 can be used in the study of respiratory tract infections .

HY-A0161

Chlophedianol Clofedanol; Calmotusin; NSC 113595	Others	Infection
Chlophedianol (Clofedanol) is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs) .

HY-A0111R

Cefetamet (Standard)	Antibiotic Bacterial	Infection
Cefetamet (Standard) is the analytical standard of Cefetamet. This product is intended for research and analytical applications. Cefetamet is a cephalosporin antibiotic. Cefetamet has the potential for the research of both upper and lower community-acquired respiratory tract infections .

HY-105263

EM574	Motilin Receptor	Metabolic Disease
EM574 is a potent motilin receptor agonist in the human gastric antrum and rabbit gastrointestinal tract in vitro. EM574 is an erythromycin derivative .

HY-128502

Nifurtoinol	Bacterial Antibiotic	Infection
Nifurtoinol is a nitrofuran-derivative antibiotic with antibacterial effects. Nifurtoinol can be used for the research of urinary tract infections .

HY-B1717A

Oxolamine hydrochloride	Others	Inflammation/Immunology
Oxolamine (SKF-9976) hydrochloride is an orally active cough suppressant that can be used for the research of respiratory tract diseases. Oxolamine hydrochloride also exhibits anti-inflammatory effect .

HY-B1717

Oxolamine	Others	Inflammation/Immunology
Oxolamine (SKF-9976) is an orally active cough suppressant that can be used for the research of respiratory tract diseases. Oxolamine also exhibits anti-inflammatory effect .

HY-133937

Sulfametrole	Bacterial HIV	Infection
Sulfametrole is an orally active and potent antibacterial. Sulfametrole can be used for infections research, such as HIV, severe pneumonia and UTIs (urinary tract infections) .

HY-B1691

Methenamine hippurate Hexamine hippurate	Bacterial	Cancer
Methenamine hippurate (Hexamine hippurate) is an orally active urinary antiseptic agent with a wide antibacterial spectrum. Methenamine hippurate is effective against most common urinary tract pathogens .

HY-122133

CI 750	Others	Metabolic Disease
CI 750 is a potent and orally active antidiarrheal agent. CI 750 increases the motor pattern of the gastrointestinal tract. CI 750 shows a constipating activity. CI 750 shows no analgesic, addiction liability, or anticholinergic pharmacological activity .

HY-B1042

Oxolamine citrate SKF-9976 citrate; AF-438 citrate	Others	Inflammation/Immunology
Oxolamine citrate (SKF-9976 citrate) is an orally active cough suppressant that can be used for the research of respiratory tract diseases. Oxolamine citrate also exhibits anti-inflammatory effect .

HY-B0213R

Sulfameter (Standard)	Antibiotic Bacterial	Infection
Sulfameter (Standard) is the analytical standard of Sulfameter. This product is intended for research and analytical applications. Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis .

HY-A0161A

Chlophedianol hydrochloride Clofedanol hydrochloride; Calmotusin hydrochloride; NSC 113595 hydrochloride	Others	Infection
Chlophedianol (Clofedanol) hydrochloride is an orally active and potent antitussive agent. Chlophedianol hydrochloride can be used for the research of acute cough due to upper respiratory tract infections (URIs) .

HY-N1425

Tiliroside	Others	Metabolic Disease
Tiliroside, a glycosidic flavonoid, possesses anti-diabetic activities. Tiliroside is a noncompetitive inhibitor of α-amylase with a K_i value of 84.2 μM. Tiliroside inhibits carbohydrate digestion and glucose absorption in the gastrointestinal tract .

HY-103250

PF-945863	Antibiotic	Infection
PF-945863 is an orally active macrolide antibiotic that can be used for the research of multidrug resistant respiratory tract bacterial strains .

HY-159688

Cefditoren	Bacterial	Infection
Cefditoren is an orally active antibiotic with broad-spectrum antibacterial activity, capable of inhibiting both Gram-negative and Gram-positive bacteria. It has a MIC₅₀ of 0.25-0.5 mg/L against Streptococcus pneumoniae strains. Cefditoren is effective against respiratory tract infections and skin infections .

HY-144035

GLP-1R agonist 4	GCGR	Cancer
GLP-1R agonist 4 is a potent agonist of GLP-1R. Glucagon-like peptide-1 (GLP-1) is an intestinal hypoglycemic hormone secreted by L-cells in the lower gastrointestinal tract. GLP-1R agonist 4 has the potential for the research of diabetes (extracted from patent WO2019239319A1, compound 96) .

HY-B1691R

Methenamine (hippurate) (Standard)	Bacterial	Cancer
Methenamine (hippurate) (Standard) is the analytical standard of Methenamine (hippurate). This product is intended for research and analytical applications. Methenamine hippurate (Hexamine hippurate) is an orally active urinary antiseptic agent with a wide antibacterial spectrum. Methenamine hippurate is effective against most common urinary tract pathogens .

HY-B0455A

Lomefloxacin SC47111A	Bacterial Antibiotic	Infection
Lomefloxacin (SC47111A) is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .

HY-B0455B

Lomefloxacin (aspartate) SC47111A (aspartate)	Bacterial Antibiotic	Infection
Lomefloxacin (SC47111A) aspartate is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin aspartate can be used for researching respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .

HY-B0455

Lomefloxacin hydrochloride SC47111A hydrochloride	Bacterial Antibiotic	Infection
Lomefloxacin (SC47111A) hydrochloride is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin hydrochloride is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .

HY-108402

Cefodizime	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime has no renal toxic effect, good tolerance and immune regulation activity, and has the potential for severe infections of the respiratory and urinary tracts .

HY-108402A

Cefodizime sodium	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Cefodizime sodium is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime sodium has no renal toxic effect, good tolerance and immune regulation activity, and can be used for the research of severe infections of the respiratory and urinary tracts .

HY-N7950

16-Oxoalisol A	Others	Metabolic Disease
16-Oxoalisol A is a triterpene in Rhizoma Alismatis. Rhizoma Alismatis is a commonly used traditional Chinese medicine (TCM). Rhizoma Alismatis can be used for the research of urinary tract diseases .

HY-108288

Sulbactam pivoxil CP 47904	Beta-lactamase Antibiotic Bacterial	Infection
Sulbactam pivoxil is a proagent of sulbactam. Sulbactam is a β-lactamase inhibitor which poorly adsorbed from gastrointestinal tract. Sulbactam pivoxil has a better absorption than the parent agent and provides high serum levels after oral administration .

HY-A0090A

Nitrofurantoin sodium	Antibiotic Bacterial	Infection
Nitrofurantoin sodium is a potent and orally active antibacterial agent. Nitrofurantoin sodium acts as an antibiotic. Nitrofurantoin sodium can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .

HY-P3501

Fexapotide NX-1207 free acid	Apoptosis	Cancer
Fexapotide (NX-1207 free acid) induces apoptosis selectively, reducing prostate volume at a cellular level. Fexapotide can be used in lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH) research .

HY-P3501A

Fexapotide TFA NX-1207 TFA	Apoptosis	Cancer
Fexapotide (NX-1207) TFA induces apoptosis selectively, reducing prostate volume at a cellular level. Fexapotide can be used in lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH) research .

HY-W008634

Bropirimine 1 Publications Verification	Toll-like Receptor (TLR)	Cancer
Bropirimine is a synthetic agonist for toll-like receptor 7 (TLR7). Bropirimine inhibits differentiation of osteoclast precursor cells into osteoclasts via TLR7-mediated production of IFN-β. Bropirimine is an orally active immunomodulator that has demonstrated anticancer activity in transitional cell carcinoma in situ (CIS) in both the bladder and upper urinary tract .

HY-164370

Hesperidin dihydrochalcone	Others	Infection
Hesperidin dihydrochalcone is a non-toxic, high-sweetness, low-calorie sweetener. Hesperidin dihydrochalcone has many biological activities such as anti-oxidation, protection of liver and kidney, bacteriostasis and improvement of gastrointestinal tract .

HY-120384

AZD-0284 2 Publications Verification	ROR	Inflammation/Immunology
AZD-0284 is a selective inverse agonist of the nuclear receptor RORγ. AZD-0284 has the potential for plaque psoriasis vulgaris and respiratory tract disorders treatment .

HY-A0090

Nitrofurantoin 5+ Cited Publications	Bacterial Antibiotic	Infection
Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .

HY-B0455AR

Lomefloxacin (Standard)	Bacterial Antibiotic	Infection
Lomefloxacin (Standard) is the analytical standard of Lomefloxacin. This product is intended for research and analytical applications. Lomefloxacin (SC47111A) is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .

Cat. No.	Product Name	Type

HY-15935

X-Gluc Dicyclohexylamine	Chromogenic Assays
X-Gluc Dicyclohexylamine is a dye reagent for the detection of β-glucuronidase, an enzyme produced by Escherichia coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract. X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (GUS reporter system) .

HY-15935C

X-Gluc sodium

Fluorescent Dyes/Probes

X-Gluc sodium is a dye reagent for the detection of β-glucuronidase (GUS), an enzyme produced by E. coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract (GUS as a specific detection indicator). X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene, appears blue) .

Cat. No.	Product Name	Type

HY-B2196

Gastric mucin 2 Publications Verification	Native Proteins
Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma.

HY-W010169

Sodium 4-aminobenzoate 1 Publications Verification	Biochemical Assay Reagents
Sodium 4-aminobenzoate is a biochemical assay reagent. According to its structure, sodium 4-aminobenzoate exhibits antioxidant, anticoagulant, fubrinolytic and immunomodulating activities, and can be utilized as a protective agent against UV-irradiation and in diagnostic tests for the state of the gastrointestinal tract .

HY-159104

Cinnamon bark oil, from Cinnamonum zeylanicum Blume Cinnamomum Cassia oil	Co-solvents
Cinnamon bark oil, from Cinnamonum zeylanicum Blume is a antifungal agent against fungi causing respiratory tract mycoses .

HY-D1056B2

Lipopolysaccharides, from Proteus mirabilis

LPS, from bacterial (Proteus mirabilis)

Carbohydrates

Lipopolysaccharides, from Proteus mirabilis are lipopolysaccharide endotoxins and TLR-4 activators derived from Proteus mirabilis, classified as S-type LPS, which can activate pathogen-associated molecular patterns (PAMP) of the immune system and induce cellular secretion of migrasomes. Lipopolysaccharides, from Proteus mirabilis exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Proteus mirabilis is a major pathogen causing urinary tract infections and may also contribute to rheumatoid arthritis. Lipopolysaccharides, from Proteus mirabilis also exhibit potential anti-tumor effects, demonstrating in vivo inhibitory activity against solid tumors such as meningosarcoma and Walker carcinosarcoma .

Cat. No.	Product Name	Target	Research Area

HY-P10369

Betiatide	Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)	Cardiovascular Disease Inflammation/Immunology
Betiatide, as a chelating agent for Technetium-99m ( ^99mTc), is used to prepare ^99mTc-MAG3 (mercaptoacetyltriglycine), a radiopharmaceutical for renal function imaging. Betiatide is used for the diagnosis of congenital and acquired abnormalities, renal failure, urinary tract obstructions, and calculi . Betiatide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-P2636

Cholecystokinin Precursor (24-32) (rat) Prepro CCK Fragment V-9-M	Histamine Receptor	Metabolic Disease
Cholecystokinin Precursor (24-32) (rat) is a cholecystokinin precursor that can be expressed in the heart, lungs, and kidneys as well as in the gastrointestinal tract and brain. Cholecystokinin is a brain-gut peptide that stimulates gallbladder contraction and pancreatic exocrine secretion and also acts as a neurotransmitter .

HY-P1179A

Guanylin(human) TFA	Guanylate Cyclase Endogenous Metabolite	Metabolic Disease
Guanylin(human) TFA, a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) TFA is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism .

HY-P2315

Human β-defensin-1 HβD-1	Antibiotic Bacterial	Infection
Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by all epithelial surfaces, but also by circulatory cells and cells of the reproductive tract. Human β-defensin-1 has antimicrobial activities against a broad-sperm bacteria .

HY-P3501

Fexapotide NX-1207 free acid	Apoptosis	Cancer
Fexapotide (NX-1207 free acid) induces apoptosis selectively, reducing prostate volume at a cellular level. Fexapotide can be used in lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH) research .

HY-P2793

Uperolein	Neurokinin Receptor	Neurological Disease
Uperolein is a physalaemin-like endecapeptide, produced in the skin of Uperoleia rugosa and Uperoleia marmorata. Uperolein has a spasmodic effect on both the gastrointestinal tract and longitudinal muscles .

HY-P1179

Guanylin(human)	Guanylate Cyclase Endogenous Metabolite	Endocrinology Cancer
Guanylin(human), a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism .

HY-P1243

C3bot(154-182)	Peptides	Neurological Disease
C3bot(154-182) is a C3 peptide enhances recovery from spinal cord injury by improving regenerative growth of descending fiber tracts. C3bot(154-182) represents a promising tool to foster axonal protection and/or repair, as well as functional recovery after traumatic CNS injury .

HY-P1243A

C3bot(154-182) TFA	Peptides	Neurological Disease
C3bot(154-182) TFA is a C3 peptide enhances recovery from spinal cord injury by improving regenerative growth of descending fiber tracts. C3bot(154-182) TFA represents a promising tool to foster axonal protection and/or repair, as well as functional recovery after traumatic CNS injury .

HY-P10267

Neuromedin (B-30)	Bombesin Receptor	Neurological Disease Inflammation/Immunology
Neuromedin B-30 is the neuropeptide, which is orignally isolated from porcine brain and spinal cord. , and may exhibit activity in stimulating smooth-muscle. Neuromedin B causes local vasodilation, increases vascular permeability and local hyperalgesia, thereby participating in neurogenic inflammation. Neuromedin B regulates appetite, body temperature, and behavioral responses to stress. Neuromedin B is also involved in regulating smooth muscle contraction and secretory function in the gastrointestinal tract .

HY-P10473

CPN-351	Neuromedin U Receptor (NMUR)	Inflammation/Immunology
CPN-351 (compound 9a), a pentapeptide, is a selective antagonist of human NMUR1 with a pA₂ of 7.35. The antagonistic effect of CPN-351 on human NMUR1 is 10 times higher than that on NMUR2. CPN-351 can be used in the study of inflammation .

Cat. No.	Product Name	Target	Research Area

HY-P9978

Toripalimab	PD-1/PD-L1	Cancer
Toripalimab is a selective, recombinant, humanized monoclonal antibody against PD-1. Toripalimab is able to bind to PD-1 and block the interaction with its ligands. Toripalimab has exhibited primary anti-tumor effects in tumors such as melanoma, lung cancer, digestive tract tumors, hepatobiliary and pancreatic tumors, neuroendocrine neoplasms, nasopharyngeal carcinoma and urothelial carcinoma .

HY-P9944

Palivizumab 1 Publications Verification MEDI 493	RSV	Infection Inflammation/Immunology Cancer
Palivizumab (MEDI 493) is a humanized monoclonal antibody against respiratory syncytial virus (RSV). Palivizumab can bind to RSV F protein with a K_d value of 1.4 nM. Palivizumab can prevent respiratory syncytial virus infection in cotton mice .

HY-P99756

Nirsevimab MEDI8897	RSV	Infection
Nirsevimab (MEDI8897) is a recombinant monoclonal antibody against human respiratory syncytial virus (RSV). Nirsevimab has neutralizing activity against RSV A and RSV B viruses, with IC₅₀ values of 5.42 ng/mL and 9.71 ng/mL, respectively. Nirsevimab can be used for research on respiratory infections .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W009886

3,4,5-Trimethoxybenzaldehyde	Clerodendrum trichotomum Thunb. Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Verbenaceae Source classification Plants Disease Research Fields	Bacterial
3,4,5-Trimethoxybenzaldehyde is an intermediate for the synthesis of various pharmaceuticals, especially for trimethoprim used to research bacterial infections, including urinary tract pathogens infection.

HY-N1425

Tiliroside	Flavonols Structural Classification Flavonoids Classification of Application Fields Platanus occidentalis L. Source classification Phenols Polyphenols Metabolic Disease Platanaceae Plants Disease Research Fields	Others
Tiliroside, a glycosidic flavonoid, possesses anti-diabetic activities. Tiliroside is a noncompetitive inhibitor of α-amylase with a K_i value of 84.2 μM. Tiliroside inhibits carbohydrate digestion and glucose absorption in the gastrointestinal tract .

HY-20685

Palmitoylethanolamide Palmidrol; Loramine P 256	Infection Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Influenza Virus Endogenous Metabolite
Palmitoylethanolamide (Palmidrol) is an active endogenous compound which can used for preventing virus infection of the respiratory tract.

HY-B1043

Piromidic acid	Infection Structural Classification Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Endogenous metabolite Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Piromidic acid is an antibacterial agent. Piromidic acid is active against gramnegative bacteria and staphylococci and can be used for the research of intestinal, urinary, and biliary tract infections .

HY-B0439

Sulfadoxine Sulphadoxine	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Parasite HIV Antibiotic Endogenous Metabolite
Sulfadoxine(Sulphadoxine) is a long acting sulfonamide that is used, usually in combination with other agents, for respiratory, urinary tract and malarial infections. Sulfadoxine inhibits HIV replication in peripheral blood mononuclear cells.

HY-N7950

16-Oxoalisol A	Triterpenes Alisma plantago-aquatica Linn. Terpenoids Plants Alismataceae	Others
16-Oxoalisol A is a triterpene in Rhizoma Alismatis. Rhizoma Alismatis is a commonly used traditional Chinese medicine (TCM). Rhizoma Alismatis can be used for the research of urinary tract diseases .

HY-20685R

Palmitoylethanolamide (Standard) Palmidrol (Standard); Loramine P 256 (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite Influenza Virus
Palmitoylethanolamide (Standard) is the analytical standard of Palmitoylethanolamide. This product is intended for research and analytical applications. Palmitoylethanolamide (Palmidrol) is an active endogenous compound which can used for preventing virus infection of the respiratory tract.

HY-121226

Karakin	Source classification Astragalus canadensis var. mortonii (Nutt.) S.Watson Plants Fabaceae	Biochemical Assay Reagents
Karakin is a nitro toxin derived from Lotus pedunculatus. Karakin is hydrolysed rapidly to 3-NPA in gut tissue of grass grub larvae, which is enzymic and occurred mainly in the upper half of the digestive tract .

HY-B1043R

Piromidic acid (Standard)	Structural Classification Antibiotics Source classification Antibacterial Disease Research Endogenous metabolite Other Antibiotics	Bacterial Antibiotic
Piromidic acid (Standard) is the analytical standard of Piromidic acid. This product is intended for research and analytical applications. Piromidic acid is an antibacterial agent. Piromidic acid is active against gramnegative bacteria and staphylococci and can be used for the research of intestinal, urinary, and biliary tract infections .

HY-W007376R

Indole-3-carboxaldehyde (Standard) 3-Formylindole (Standard)	Alkaloids Structural Classification Human Gut Microbiota Metabolites Microorganisms Cruciferae Source classification Isatis tinctoria L. Plants Endogenous metabolite Indole Alkaloids	Endogenous Metabolite
Indole-3-carboxaldehyde (Standard) is the analytical standard of Indole-3-carboxaldehyde. This product is intended for research and analytical applications. Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract[1][2].

HY-N0677

Dehydroandrographolide succinate	Andrographis paniculata (Burm. F.) Nees Classification of Application Fields Acanthaceae Terpenoids Source classification Diterpenoids Plants Disease Research Fields Inflammation/Immunology Cancer	Influenza Virus
Dehydroandrographolide succinate, extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect .

HY-N7504

Isopsoralenoside	Infection Classification of Application Fields Leguminosae Ketones, Aldehydes, Acids Source classification Metabolic Disease Psoralea corylifolia L. Plants Disease Research Fields	Bacterial
Isopsoralenoside is a benzofuran glycoside from Psoralea corylifolia. Isopsoralenoside can be quickly metabolized to Psoralen (HY-N0053) in digestive tract contents. Isopsoralenoside show estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .

HY-B1908R

Midecamycin (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Antibacterial Disease Research	Bacterial Antibiotic
Lomefloxacin (Standard) is the analytical standard of Lomefloxacin. This product is intended for research and analytical applications. Lomefloxacin (SC47111A) is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .

HY-B0439R

Sulfadoxine (Standard) Sulphadoxine (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Parasite HIV Antibiotic Endogenous Metabolite
Sulfadoxine (Standard) is the analytical standard of Sulfadoxine. This product is intended for research and analytical applications. Sulfadoxine(Sulphadoxine) is a long acting sulfonamide that is used, usually in combination with other agents, for respiratory, urinary tract and malarial infections. Sulfadoxine inhibits HIV replication in peripheral blood mononuclear cells.

HY-N7665

Prosaikogenin G	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Metabolic Disease Umbelliferae Plants Disease Research Fields Carphephorus corymbosus (Nutt.) Torr. & A.Gray	Others
Prosaikogenin G, isolated from the roots of Bupleurum chinensis DC., exhibits significant inhibitory effects on rat mesangial cell proliferation induced by Ang II. Prosaikogenin G has protective action on the kidney . Prosaikogenin G is a derivative of Saikosaponin d in the gastrointestinal tract .

HY-N0677A

Kalii Dehydrographolidi Succinas Potassium dehydroandrographolide succinate	Structural Classification Andrographis paniculata (Burm. F.) Nees Classification of Application Fields Acanthaceae Terpenoids Source classification Diterpenoids Plants Inflammation/Immunology Disease Research Fields Cancer	Antibiotic
Kalii Dehydrographolidi Succinas (Potassium dehydroandrographolide succinate), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect .

HY-N1425R

Tiliroside (Standard)	Structural Classification Flavonoids Classification of Application Fields Platanus occidentalis L. Source classification Phenols Metabolic Disease Platanaceae Plants Disease Research Fields	Others
Tiliroside (Standard) is the analytical standard of Tiliroside. This product is intended for research and analytical applications. Tiliroside, a glycosidic flavonoid, possesses anti-diabetic activities. Tiliroside is a noncompetitive inhibitor of α-amylase with a K_i value of 84.2 μM. Tiliroside inhibits carbohydrate digestion and glucose absorption in the gastrointestinal tract .

HY-W015591

Mandelic acid 1 Publications Verification (±)-Mandelic acid; DL-Mandelic acid	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Bacterial Endogenous Metabolite
Mandelic acid ((±)-Mandelic acid), an alpha-hydroxycarboxylic acid, has been widely used as an intermediate of pharmaceutical and fine chemicals. Mandelic acid shows antimicrobial activity and has been used for the research of urinary tract infections and vaginal trichomoniasis. Mandelic acid exhibits high sperm-immobilizing activity and low vaginal irritation .

HY-B1150

Clofoctol	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Infection Monophenols Microorganisms Antibiotics Phenols Antiviral Anticancer Disease Research Fields	Bacterial SARS-CoV Antibiotic
Clofoctol is a bacteriostatic antibiotic. Clofoctol is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. Clofoctol is only functional against Gram-positive bacteria and can penetrate into human lung tissue. Clofoctol is also an inhibitor of prostate cancer. Clofoctol has antiviral potency .

HY-125923

Djenkolic acid	other families Source classification Metabolic Disease Amino acids Plants Disease Research Fields Archidendron jiringa	Others
Djenkolic acid is a sulfur-containing non-protein amino acid naturally found in the djenkol beans of the Southeast Asian plant Archidendron jiringa. Djenkolic Acid often causes renal injury, including hypersensitivity to or a direct toxic effect of a djenkol bean metabolite, resulting in acute kidney injury and/or urinary tract obstruction by djenkolic acid crystals, sludge, and/or possible ureteral spasms .

HY-W015591R

Mandelic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Bacterial Endogenous Metabolite
Mandelic acid (Standard) is the analytical standard of Mandelic acid. This product is intended for research and analytical applications. Mandelic acid ((±)-Mandelic acid), an alpha-hydroxycarboxylic acid, has been widely used as an intermediate of pharmaceutical and fine chemicals. Mandelic acid shows antimicrobial activity and has been used for the research of urinary tract infections and vaginal trichomoniasis. Mandelic acid exhibits high sperm-immobilizing activity and low vaginal irritation .

HY-D0184R

2'-Deoxycytidine (Standard)	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
Cefaclor (monohydrate) (Standard) is the analytical standard of Cefaclor (monohydrate). This product is intended for research and analytical applications. Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections .

HY-139104

Thailanstatin D	Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Cancer	DNA/RNA Synthesis Apoptosis
Thailanstatin D, an analogue of Thailanstatin A, is able to inhibit AR-V7 gene splicing by interfering the interaction between U2AF65 and SAP155 and preventing them from binding to polypyrimidine tract located between the branch point and the 3' splice site. Thailanstatin D exhibits a potent tumor inhibitory effect on human CRPC xenografts leading to cell apoptosis .

HY-B1150R

Clofoctol (Standard)	Structural Classification Monophenols Microorganisms Antibiotics Source classification Phenols Antiviral Antibacterial Disease Research Anticancer Other Antibiotics	Bacterial SARS-CoV Antibiotic
Clofoctol (Standard) is the analytical standard of Clofoctol. This product is intended for research and analytical applications. Clofoctol is a bacteriostatic antibiotic. Clofoctol is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. Clofoctol is only functional against Gram-positive bacteria and can penetrate into human lung tissue. Clofoctol is also an inhibitor of prostate cancer. Clofoctol has antiviral potency .

HY-W007376

Indole-3-carboxaldehyde 2 Publications Verification 3-Formylindole	Structural Classification Classification of Application Fields Source classification Plants Endogenous metabolite Indole Alkaloids Alkaloids Human Gut Microbiota Metabolites Microorganisms Cruciferae Other Diseases Isatis tinctoria L. Disease Research Fields	Endogenous Metabolite
Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract .

Cat. No.	Product Name	Chemical Structure

HY-20685S

Palmitoylethanolamide-d4
Palmitoylethanolamide-d₄ is the deuterium labeled Palmitoylethanolamide. Palmitoylethanolamide (Palmidrol) is an active endogenous compound which can used for preventing virus infection of the respiratory tract.

HY-B0035S

Sulfamethazine-d4
Sulfamethazine-d₄ is a deuterium labeled Sulfamethazine (Sulfadimidine). Sulfamethazine is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections)[1][2].

HY-B0337S

Sulfadimethoxine-d4
Sulfadimethoxine-d₄ is a deuterium labeled Sulfadimethoxine (Sulphadimethoxine). Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections[1].

HY-B0439S

Sulfadoxine-d4
Sulfadoxine-d₄ is the deuterium labeled Sulfadoxine. Sulfadoxine(Sulphadoxine) is a long acting sulfonamide that is used, usually in combination with other agents, for respiratory, urinary tract and malarial infections. Sulfadoxine inhibits HIV replication in peripheral blood mononuclear cells.

HY-B0455S

Lomefloxacin-d5 hydrochloride
Lomefloxacin-d₅ (hydrochloride) is the deuterium labeled Lomefloxacin hydrochloride. Lomefloxacin (SC47111A) hydrochloride is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin hydrochloride is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc.[1][2].

HY-B1085S

Cinoxacin-d5

Cinoxacin-d₅ is the deuterium-labeled Cinoxacin (HY-B1085) . Cinoxacin (Compound 64716)，a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis .

HY-14153AS

Tegaserod-13C,d3 maleate
Tegaserod- ¹³C,d₃ (maleate) is the ¹³C- and deuterium labeled Tegaserod (maleate). Tegaserod maleate is a selective 5-HT4 receptor partial agonist and a 5-HT2B receptor antagonist. Tegaserod maleate exhibits a promotile effect throughout the gastrointestinal (GI) tract[1][2][5].

HY-B0395S

Sitafloxacin-d4

Sitafloxacin-d₄ (DU6859a-d₄) is deuterium labeled Sitafloxacin. Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection .

HY-W719074

Sulfisomidin-d4
Sulfisomidin-d₄ (Sulfaisodimidine-d₄) is deuterium labeled Sulfisomidin. Sulfisomidin (Sulfaisodimidine) is an orally active short-acting sulfonamide antibacterial. Sulfisomidin can be used for the research of lower urinary tract infections .

HY-B0213S1

Sulfameter-13C6
Sulfameter- ¹³C₆ is the ¹³C₆ labeled Sulfameter. Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis.

HY-A0161S

Chlophedianol-13C6
Chlophedianol- ¹³C₆ is the ¹³C labeled Chlophedianol (HY-A0161). Chlophedianol is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs)[1][2][3].

HY-W009886S

3,4,5-Trimethoxybenzaldehyde-d3
3,4,5-Trimethoxybenzaldehyde-d3 is the deuterium labeled 3,4,5-Trimethoxybenzaldehyde. 3,4,5-Trimethoxybenzaldehyde is an intermediate for the synthesis of various pharmaceuticals, especially for trimethoprim used to research bacterial infections, including urinary tract pathogens infection.

HY-20685S2

Palmitoylethanolamide-d5
Palmitoylethanolamide-d₅ (Palmidol-d₅, PEA-15,15,16,16,16-d₅) is deuterium labeled Palmitoylethanolamide. Palmitoylethanolamide (Palmidrol) is an active endogenous compound which can used for preventing virus infection of the respiratory tract .

HY-B1139S

Tolperisone-d10 hydrochloride

Tolperisone-d₁₀ (hydrochloride) is the deuterium labeled Tolperisone hydrochloride. Tolperisone hydrochloride is a centrally acting muscle relaxant, is indicated for use in the treatment of pathologically increased tone of the cross-striated muscle caused by neurological diseases (damage of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis) and of spastic paralysis and other encephalopathies manifested with muscular dystonia.

HY-B0510S

Trimethoprim-d9
Trimethoprim-d₉ is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment[1][2][3].

HY-A0090S

Nitrofurantoin-13C3
Nitrofurantoin- ¹³C₃ is the ¹³C labeled Nitrofurantoin (HY-A0090) . Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .

HY-111613S

Pinaverium bromide-d4
Pinaverium bromide-d₄ is deuterium labeled Pinaverium bromide. Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract, effectively relieves pain, diarrhea and intestinal discomfort, provides good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients[1].

HY-B0510S2

Trimethoprim-d3
Trimethoprim-d₃is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment[1][2][3].

HY-B0213S

Sulfameter-d4
Sulfameter-d₄ (Sulfametoxydiazine-d₄; 5-Methoxysulfadiazine-d₄) is the deuterium labeled Sulfameter (HY-B0213) . Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis .

HY-A0118AS

Naloxegol-d5 oxalate
Naloxegol-d₅ (oxalate) is deuterium labeled Naloxegol (oxalate). Naloxegol oxalate (NKTR-118 oxalate; AZ-13337019 oxalate) is a μ-opioid-receptor antagonist. Naloxegol oxalate inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation[1][2].

HY-B0337S1

Sulfadimethoxine-d6
Sulfadimethoxine-d₆ is the deuterium labeled Sulfadimethoxine. Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections[1].

HY-B1002S

Oxolinic acid-d5
Oxolinic acid-d₅ is the deuterium labeled Oxolinic acid. Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice[1][2][3].

HY-W653919

SN-38 glucuronide-d3
SN-38 glucuronide-d₃ is deuterium labeled SN-38 glucuronide. SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan (HY-16562) and has toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer .

HY-A0118S1

Naloxegol-13C,d2
Naloxegol- ¹³C,d₂ (NKTR-118- ¹³C,d₂) is ¹³C labeled Naloxegol. Naloxegol (NKTR-118; AZ-13337019) is a μ-opioid-receptor antagonist. Naloxegol inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation .

HY-A0118S

Naloxegol-13C,d3
Naloxegol- ¹³C,d₃ (NKTR-118- ¹³C,d₃) is ¹³C labeled Naloxegol. Naloxegol (NKTR-118; AZ-13337019) is a μ-opioid-receptor antagonist. Naloxegol inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation .

HY-B0035S2

Sulfamethazine-13C6
Sulfamethazine- ¹³C₆ is a ¹³C-labeled n-Acetyl-s-methyl-l-cysteine[1].

HY-W015591S

Mandelic acid-2,3,4,5,6-d5

Mandelic acid-2,3,4,5,6-d₅ is the deuterium labeled Mandelic acid. Mandelic acid ((±)-Mandelic acid), an alpha-hydroxycarboxylic acid, has been widely used as an intermediate of pharmaceutical and fine chemicals. Mandelic acid shows antimicrobial activity and has been used for the research of urinary tract infections and vaginal trichomoniasis. Mandelic acid exhibits high sperm-immobilizing activity and low vaginal irritation[1][2].

HY-B0439S1

Sulfadoxine D3

Sulfadoxine-d₃ is a deuterium labeled Sulfadoxine (HY-B0439). Sulfadoxine is a sulfonamide that is used, usually in combination with Pyrimethamine (HY-18062), for multidrug-resistant Plasmodium falciparum and P. vivax inhibition. Unlike PYR, Sulfadoxine has no impact on HIV replication or MT-2 cell cycle progression. But also Sulfadoxine exhibits suppression on respiratory, and urinary tract infections[1][2][3][4].

HY-B1159S1

Nitroxoline-d5
Nitroxoline-d₅ (8-Hydroxy-5-nitroquinoline-d₅) is deuterium labeled Nitroxoline. Nitroxoline (8-Hydroxy-5-nitroquinoline), an antibiotic, is an orally active antibiofilm agent. Nitroxoline reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc. Nitroxoline can be used for the urinary tract infections and cancer research .

HY-118189S

Misoprostol acid-d5

Misoprostol acid-d₅ is deuterium labeled Misoprostol acid. Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers[1]. Misoprostol is an oral agent used to induce labor[2].

HY-B0510S3

Trimethoprim-13C3

Trimethoprim- ¹³C₃ is the deuterium labeled Trimethoprim (HY-B0510) . Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc .

HY-A0294S

Ertapenem-d4
Ertapenem-d₄ (MK-0826-d₄) is deuterium labeled Ertapenem. Ertapenem (MK-0826) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .

HY-B0322S

Sulfamethoxazole-d4

1 Publications Verification

Sulfamethoxazole-d₄ (Ro 4-2130-d₄) is a deuterium labeled Sulfamethoxazole (HY-B0322). Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .

HY-B0322S1

Sulfamethoxazole-13C6

Sulfamethoxazole- ¹³C₆ (Ro 4-2130- ¹³C₆) is a ¹³C labeled Sulfamethoxazole (HY-B0322). Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis .

HY-B1339AS

Dicyclomine-d4

Dicyclomine-d₄ is the deuterium labeled Dicyclomine[1]. Dicyclomine (Dicycloverine) is a potent and orally active muscarinic cholinergic receptors antagonist. Dicyclomine (Dicycloverine) shows high affinity for muscarinic M1 receptor subtype (Ki=5.1 nM) and M2 receptor subtype (Ki=54.6 nM) in brush-border membrane and basal plasma membranes, respectively[2]. Dicyclomine is an antispasmodic agent and relieves smooth muscle spasm of the gastrointestinal tract in vivo[3].

HY-B1415S

Clofibric acid-d4

Clofibric acid-d₄ is the deuterium labeled Clofibric acid (HY-B1415). Clofibric acid also is an herbicideClofibric acid (Chlorofibrinic acid) is an orally active PPARα agonist. Clofibric acid inhibits the fimbriation of Escherichia coli. Clofibric acid increases SOD activity. Clofibric acid lowers blood lipids and prevents experimental pyelonephritis. Clofibric acid has anticancer activity against ovarian cancer. Clofibric acid is also a herbicide. Clofibric acid is used in ovarian cancer, liver cancer, obesity, and urinary tract infection research .

HY-W750674

Indole-3-carboxaldehyde-13C8

Indole-3-carboxaldehyde- ¹³C₈ (3-Formylindole- ¹³C₈) is the ¹³C-labeled Indole-3-carboxaldehyde (HY-W007376). Indole-3-carboxaldehyde, a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract .

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