2. Anti-infection
  3. RSV
  4. JNJ-7950

JNJ-7950 (compound 5c) exhibits antiviral activity against RSV with an EC50 value of 0.78 nM. JNJ-7950 can be used in the study of respiratory tract infections.

For research use only. We do not sell to patients.

JNJ-7950

JNJ-7950 Chemical Structure

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JNJ-7950 Related Antibodies

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Description

JNJ-7950 (compound 5c) exhibits antiviral activity against RSV with an EC50 value of 0.78 nM. JNJ-7950 can be used in the study of respiratory tract infections[1].

Molecular Weight

526.96

Formula

C23H22ClF3N4O3S
Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC=C2N(C(CN3C4=C(C5(C3=O)CN(C5)S(C)(=O)=O)C=CC=C4)=NC2=C1)CCCC(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 27.78 mg/mL (52.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8977 mL 9.4884 mL 18.9768 mL
5 mM 0.3795 mL 1.8977 mL 3.7954 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8977 mL 9.4884 mL 18.9768 mL 47.4419 mL
5 mM 0.3795 mL 1.8977 mL 3.7954 mL 9.4884 mL
10 mM 0.1898 mL 0.9488 mL 1.8977 mL 4.7442 mL
15 mM 0.1265 mL 0.6326 mL 1.2651 mL 3.1628 mL
20 mM 0.0949 mL 0.4744 mL 0.9488 mL 2.3721 mL
25 mM 0.0759 mL 0.3795 mL 0.7591 mL 1.8977 mL
30 mM 0.0633 mL 0.3163 mL 0.6326 mL 1.5814 mL
40 mM 0.0474 mL 0.2372 mL 0.4744 mL 1.1860 mL
50 mM 0.0380 mL 0.1898 mL 0.3795 mL 0.9488 mL
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JNJ-7950 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JNJ-7950JNJ7950JNJ 7950RSVRespiratory syncytial virusAntiviralrespiratory tract infectionInhibitorinhibitorinhibit

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