Search Result
Results for "
rhizomes
" in MedChemExpress (MCE) Product Catalog:
2
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-121083
-
|
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Others
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Others
|
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Aerugidiol is a bridge-head oxygenated sesquiterpene isolated from the rhizomes of Curcuma aeruginosa .
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-
-
- HY-N7582
-
|
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Others
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Others
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Cimicifugoside H-2 is a cyclolanostanol xyloside. Cimicifugoside H-2 can be isolated from Cimicifuga Rhizome .
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-
-
- HY-N3630
-
|
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Others
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Others
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Coronarin D is a cytotoxic labdan-type diterpenes compound isolated from the rhizomes of H. coronarium .
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-
-
- HY-N10892
-
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Others
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Others
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Officinaruminane B (compound 2), a diarylheptanoid, is a nature product that could be isolated from the rhizome of Alpinia officinarum .
|
-
-
- HY-N3633
-
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(+)-Coronarin E
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Others
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Others
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Coronarin E is a compound isolated from the rhizome of Hedychium coronarium (Zingiberaceae) .
|
-
-
- HY-107236
-
|
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Others
|
Others
|
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Huzhangoside D is a saponin compound isolated from the roots and rhizomes of Clematis graveolens .
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-
-
- HY-N13194
-
|
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Others
|
Metabolic Disease
|
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(2R)-Pteroside B is a pterosin-associated glycoside from the rhizomes of subsp. aquilinum of bracken fern, which is promising for research of diabetic diseases .
|
-
-
- HY-N3631
-
|
|
COX
|
Inflammation/Immunology
|
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Ethoxycoronarin D is a labdane diterpenes compound isolated from rhizomes. Ethoxycoronarin D selectively inhibits COX-1 with an IC50 of 3.8 µM .
|
-
-
- HY-N10792
-
|
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Others
|
Others
|
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Methyl diacetoxy-6-gingerdiol is a nature product that could be isolated form the rhizomes of Zingiber officinale .
|
-
-
- HY-N10640
-
|
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FXR
|
Inflammation/Immunology
|
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Alismanol M is a farnesoid X receptor (FXR) agonist with an EC50 value of 50.25 μM. Alismanol M is a protostane-type triterpenoid that can be isolated from the rhizome of Alisma orientale. Alismanol M can be used for the research of cholestasis and nonalcoholic steatohepatitis .
|
-
-
- HY-N0836
-
Jervine
3 Publications Verification
11-Ketocyclopamine
|
Hedgehog
Smo
|
Inflammation/Immunology
Cancer
|
|
Jervine (11-Ketocyclopamine) is a potent Hedgehog (Hh) inhibitor with an IC50 of 500-700 nM . Jervine is a natural teratogenic sterodial alkaloid from rhizomes of Veratrum nigrum. Jervine has anti-inflammatory and antioxidant properties .
|
-
-
- HY-N5033
-
|
|
Bcl-2 Family
Caspase
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Cancer
|
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17-Hydroxy sprengerinin C (compound 10) is a glycoside compound isolated from rhizomes of Polygonatum sibiricum. 17-Hydroxy sprengerinin C possesses stronger anticancer activities. 17-Hydroxy sprengerinin C reduces the expression of Blc-2 and pro-caspase3 and increases the production of Bax .
|
-
-
- HY-N0836R
-
|
11-Ketocyclopamine (Standard)
|
Reference Standards
Hedgehog
Smo
|
Inflammation/Immunology
Cancer
|
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Jervine (Standard) is the analytical standard of Jervine. This product is intended for research and analytical applications. Jervine (11-Ketocyclopamine) is a potent Hedgehog (Hh) inhibitor with an IC50 of 500-700 nM . Jervine is a natural teratogenic sterodial alkaloid from rhizomes of Veratrum nigrum. Jervine has anti-inflammatory and antioxidant properties .
|
-
-
- HY-N9183
-
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Others
|
Inflammation/Immunology
|
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Diarylcomosol III, a diarylheptanoid, can be isolated from dried rhizomes of Curcuma comosa. The rhizome of Curcuma comosa has aromatic stomachic and anti-inflammatory activity .
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-
-
- HY-N1955
-
-
-
- HY-N12505
-
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Others
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Others
|
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Ponasteroside A is a phytoecdysteroid isolated from the rhizomes of Brainea insignis .
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-
-
- HY-N7792
-
|
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Others
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Others
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Baptifoline is an alkaloid isolated from the rhizome of Caulophyllum thalictroides .
|
-
-
- HY-N1145
-
-
-
- HY-N2120
-
|
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Others
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Others
|
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Dichotomitin is an isoflavonoid isolated from the rhizomes of Belamcanda chinensis (L.) DC .
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-
-
- HY-N2398
-
|
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Others
|
Others
|
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Rehmapicroside is an ionone glycoside isolated from rhizomes of Rehmannia glutinosa .
|
-
-
- HY-N12506
-
|
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Others
|
Others
|
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Cimicifugic acid F is a hydroxycinnamic acid ester of piscidic acid isolated from the rhizomes of Cimicifuga racemosa.
|
-
-
- HY-N3768
-
|
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Others
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Others
|
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Diosbulbin L is a Diterpenoids product that can be isolated from the rhizomes of Dioscorea bulbifera. .
|
-
-
- HY-N8558A
-
|
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Others
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Others
|
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Senkyunolide J, a phthalide, can be isolated from rhizome of Ligusticum Chuanxiong .
|
-
-
- HY-N8558
-
|
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Others
|
Others
|
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Senkyunolide N, a phthalide, can be isolated from rhizome of Ligusticum Chuanxiong .
|
-
-
- HY-N6243
-
-
-
- HY-N3538
-
|
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Others
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Others
|
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Carabrolactone A is a Sesquiterpenoids product that can be isolated from the rhizomes of Carpesium abrotanoides .
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-
-
- HY-N11974
-
|
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Others
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Others
|
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Isobatatasin I is a phenanthrene derivative that can be isolated from the rhizome of safflower .
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-
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- HY-N2856
-
|
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Others
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Others
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Alpiniaterpene A is a Sesquiterpenoids product that can be isolated from the rhizomes of Alpinia officinarum. .
|
-
-
- HY-120922
-
|
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Others
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Others
|
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Spiroakyroside is a steroidal compound that can be isolated from the fresh rhizome of Polygonatum cyrtonema.
|
-
-
- HY-N9202
-
|
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Others
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Others
|
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Galanganone A is a Chalcones product that can be isolated from the rhizomes of Alpinia galanga. .
|
-
-
- HY-N3572
-
|
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Others
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Others
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Chinensine B is a Diterpenoids product that can be isolated from the rhizomes of Alpinia chinensis .
|
-
-
- HY-N12643
-
|
[6]-Gingerdione
|
PGE synthase
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Others
|
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[6]-Gingerdione is a prostaglandin synthesis inhibitor that can be isolated from ginger rhizomes.
|
-
-
- HY-N9667
-
|
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Others
|
Others
|
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Stilbostemin N can be isolated from ated from the rhizomes of D. japonica .
|
-
-
- HY-N3539
-
|
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Others
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Others
|
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Carabrolactone B is a Sesquiterpenoids product that can be isolated from the rhizomes of Carpesium abrotanoides .
|
-
-
- HY-N1285
-
|
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Others
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Others
|
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Senkyunolide C is a natural product, that can be isolated from the rhizome of Cnidium officinale .
|
-
-
- HY-N12066
-
|
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Others
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Others
|
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Progenin III palmitate is a steroid glycoside ester isolated from Dioscorea cayenensis rhizomes .
|
-
-
- HY-W015879
-
|
|
Bacterial
|
Inflammation/Immunology
|
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2-Heptanol is one of the chemical compounds identified in turmeric and turmeric rhizome essential oil. 2-Heptanol can speed up amino acid metabolism and slow down membrane transport, exhibiting antibacterial activity. The rhizome essential oil has good antibacterial and antioxidant properties .
|
-
-
- HY-N3833
-
|
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Others
|
Others
|
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Epipterosin L is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
-
- HY-133237
-
|
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Others
|
Others
|
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Anemarrhenasaponin III is a steroidal saponin isolated from the rhizome of Anemarrhena asphodeloides Bunge (Liliaceae) .
|
-
-
- HY-N2836
-
|
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Others
|
Others
|
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Alepterolic acid is a Diterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
-
- HY-N11810
-
|
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Others
|
Others
|
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Polyfuroside is a triterpenoid saponin, which can be isolated from the defatted rhizome of jade bamboo .
|
-
-
- HY-N8790
-
|
|
Others
|
Others
|
|
24-Methylenecycloartanone is a Triterpenoids product that can be isolated from the rhizomes of Polygonum bistorta. .
|
-
-
- HY-N4123
-
|
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Others
|
Others
|
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Orcinol gentiobioside (compound 4) is a natural product isolated from the rhizomes of C. breviscapa .
|
-
-
- HY-N2930
-
|
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Others
|
Others
|
|
β-Peltoboykinolic acid is a Triterpenoids product that can be isolated from the rhizomes of Astilbe koreana. .
|
-
-
- HY-N8814
-
|
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Others
|
Others
|
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Parisyunnanoside B is a Steroids product that can be isolated from the rhizomes of Paris yunnanensis Franch. .
|
-
-
- HY-125686
-
|
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Others
|
Others
|
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Beesioside Q is a oleanolic acid triterpene saponin isolated from the rhizome of Beesia calthaefolia (Maxim.) Ulbr .
|
-
-
- HY-N8715
-
|
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Others
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Others
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Cimilactone A is a cycloartane-type triterpene glycoside. Cimilactone A can be isolated from the rhizomes of Cimicifuga foetida .
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-
-
- HY-N3869
-
|
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Others
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Others
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Ethyl-p-methoxyhydrocinnamate is a phenolic compound that can be isolated from the edible rhizomes of Erythrina variegate .
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-
-
- HY-125932
-
|
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Others
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Others
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Debilon, a diterpene compound, is a natural product that could be isolated from the roots and rhizomes of Nardostachys chinensis .
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-
-
- HY-N13702
-
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Others
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Others
|
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Secoaristolenedioic acid (Compound 1) is a sesquiterpene, which is found in ethanol extract of the roots and rhizomes of Nardostachys chinensis .
|
-
- HY-N1909
-
|
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Others
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Others
|
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4-O-Galloylbergenin is a bergenin derivative that can be isolated from the rhizome of Ardisia gigantifolia .
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-
- HY-W795244
-
|
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Others
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Others
|
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ω-Benzoyl oxyphloracetophenone is a Phenols product that can be isolated from the rhizomes of Curcuma comosa .
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-
- HY-N1573
-
|
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Others
|
Others
|
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Pterosin Z is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
- HY-N9231
-
|
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Others
|
Others
|
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4'-O-Methylirenolone is a Phenols product that can be isolated from the rhizomes of Musa acuminata .
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-
- HY-N8689
-
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Others
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Others
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4-Epi-curcumenol is a Sesquiterpenoids product that can be isolated from the rhizomes of Curcuma zedoaria .
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-
- HY-N12363
-
|
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Others
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Others
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(-)-Afzelechin is a compound isolated from the rhizomes of Astilbe rivularis. (-)-Afzelechin shows poitent antioxidant activity .
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-
- HY-N9201
-
|
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Others
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Others
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8beta-Methoxyatractylenolide I is a Sesquiterpenoids product that can be isolated from the rhizomes of Atractylodes macrocephala. .
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-
- HY-125100
-
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Others
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Others
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Loroglossin (compound 5) is a succinate derivative. Loroglossin can isolated from dried rhizomes of Gymnadenia conopsea .
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-
- HY-N2505
-
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Others
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Inflammation/Immunology
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Iristectorigenin A is a natural isoflavone isolated from B. chinensis rhizomes. Iristectorigenin A shows antioxidant activity .
|
-
- HY-N12029
-
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Others
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Others
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Acacetin 7-O-β-sophoroside is a flavonoid glycoside isolated from the rhizomes and roots of valerian .
|
-
- HY-N2401
-
-
- HY-N4174
-
-
- HY-N1304
-
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Shyobunon
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Others
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Others
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Shyobunone (Shyobunon) is a nature product that could be isolated from Acorus calamus rhizomes. Shyobunone has insecticidal and repellant activity .
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-
- HY-N4306
-
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Others
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Cancer
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Sarracenin is a iridoid isolated from roots and rhizomes of Patrinia heterophylla. Sarracenin shows cytotoxic activities against tumor cells .
|
-
- HY-N9691
-
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α-Curcumene
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Others
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Others
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α-curcumene (compound 12) is isolated from the essential oil of rhizomes of Curcuma aromatica and can be synthesized artificially .
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-
- HY-N11665
-
|
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Others
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Infection
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Donasine, indole alkaloid, is a nature product with effect of reducing fever. Donasine can be isolated from the rhizomes of Arundo donax L .
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-
- HY-N3834
-
|
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Others
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Others
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Epipterosin L 2'-O-glucoside is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
- HY-N7960
-
|
|
Others
|
Metabolic Disease
|
|
(2S)-Pteroside A is a pteroside from the rhizomes of subsp. aquilinum of bracken fern, which is promising for research of diabetic diseases .
|
-
- HY-N1572
-
|
|
Others
|
Others
|
|
Pterosin D 3-O-glucoside is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
- HY-123080
-
|
|
Others
|
Others
|
|
Tanshinol B is a bioactive component of Salvia miltiorrhiza, which can be isolated from the 50% ethanol extract of the roots and rhizomes of Seaweed prowazekii .
|
-
- HY-N8262
-
|
|
Influenza Virus
|
Infection
|
|
Dehydrocorybulbine chloride is an isoquinoline alkaloid with neuraminidase (NA) inhibitory activity. Dehydrocorybulbine chloride can be isolated from the 95% ethanol extract of the rhizome of Viola odorata .
|
-
- HY-N8652
-
|
|
Others
|
Others
|
|
25-Anhydrocimigenol-3-O-β-D-xylopyranoside is a compound that can be isolated from the roots or rhizomes of Cimicifuga racemosa .
|
-
- HY-N12150
-
|
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MMP
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Others
|
|
Isozedoarondiol can be isolated from the rhizomes of Curcuma xanthorrhiza Roxb. Isozedoarondiol inhibits MMP-1 expression in UVB-treated human keratinocytes .
|
-
- HY-N9177
-
|
|
Others
|
Others
|
|
3',4'-Dihydroxy-2-O-methylanigorufone is a Phenols product that can be isolated from the rhizomes of Musa acuminata var. .
|
-
- HY-N15724
-
|
2-E-Feruloylpiscidic acid
|
Others
|
Others
|
|
Cimicifugic acid E (2-E-Feruloylpiscidic acid) is a ferulic acid ester compound found in the rhizomes of Cimicifuga racemosa. Cimicifugic acid E is promising for research of menopausal syndrome .
|
-
- HY-N8951
-
|
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Others
|
Others
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|
3,4-Dihydroxybisabola-1,10-diene is a Sesquiterpenoids product that can be isolated from the rhizomes of Curcuma xanthorrhiza Roxb .
|
-
- HY-133223
-
|
|
Others
|
Cancer
|
|
Hispidanin B is a natural product that can be extracted from the rhizomes of Isodon hispida. Hispidanin B has cytotoxic activities against cancer cells .
|
-
- HY-N7798
-
-
- HY-W015879R
-
|
|
Reference Standards
Bacterial
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Inflammation/Immunology
|
|
2-Heptanol (Standard) is the analytical standard of 2-Heptanol. This product is intended for research and analytical applications. 2-Heptanol is one of the chemical compounds identified in turmeric and turmeric rhizome essential oil. 2-Heptanol can speed up amino acid metabolism and slow down membrane transport, exhibiting antibacterial activity. The rhizome essential oil has good antibacterial and antioxidant properties[1][2].
|
-
- HY-W015879S
-
|
|
Bacterial
Isotope-Labeled Compounds
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Inflammation/Immunology
|
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2-Heptanol-d5 is deuterated labeled 2-Heptanol (HY-W015879). 2-Heptanol is one of the chemical compounds identified in turmeric and turmeric rhizome essential oil. 2-Heptanol can speed up amino acid metabolism and slow down membrane transport, exhibiting antibacterial activity. The rhizome essential oil has good antibacterial and antioxidant properties .
|
-
- HY-N5108
-
|
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Others
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Others
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|
4β,12-Dihydroxyguaian-6,10-diene, a natural terpene, is isolated from the rhizomes of Alisma orientale .
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-
- HY-128683
-
|
|
Biochemical Assay Reagents
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Others
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Cycloposine is a steroidal alkaloid that can be found in the roots and rhizomes of Veratrum californicum. Cycloposine is also a teratogenic compound that may induce cyclopia in pregnant Mianyang embryos .
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-
- HY-N10694
-
|
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Others
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Others
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|
Rehmannioside B is a desacyl derivative of Picrorhizaoside B, which can be isolated from the methanol extract of the rhizomes of Picrorhiza kurroa Royle ex Benth. (Plantaginaceae) .
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-
- HY-N8990
-
|
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Others
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Others
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|
Aristola-1(10),8-dien-2-one is a sesquiterpene compound that can be isolated from rhizome of Nardostachys chinensis of Valerianaceae .
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-
- HY-N4062
-
|
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Others
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Others
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|
Hedychenone (compound 3) is a labdane diterpene. Hedychenone can be isolated from the rhizomes of Hedychium yunnanense. Hedychenone against HeLa cell with IC50 value of 9.76 μg/ml.
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-
- HY-N0812
-
-
- HY-N12215
-
|
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Others
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Others
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10-Hydroxyoleuropein (compound 11) is isolated from the rhizome of Cyperus rotundus. 10-Hydroxyoleuropein inhibits the respiratory burst of macrophages (IC50: 693 μM) .
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-
- HY-N10047
-
|
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NF-κB
PPAR
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Cardiovascular Disease
|
|
7,8-Didehydrocimigenol is an active triterpenoid that can be isolated from Cimicifugae rhizoma. 7,8-Didehydrocimigenol inhibits TNF-α-induced VCAM-1 expression, inhibits NF-kB activity and phosphorylation of ERK1/2 and Akt, increases PPAR-γ expression. 7,8-Didehydrocimigenol can be used for the research of cardiovascular disorders such as atherosclerosis .
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-
- HY-N2762
-
|
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Others
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Others
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Labda-8(17),13(14)-dien-15,16-olide is a Diterpenoids product that can be isolated from the rhizomes of Alpinia chinensis .
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-
- HY-N7614
-
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Schidigerasaponin F2; Timosaponin AII
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Others
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Cardiovascular Disease
|
|
Anemarrhenasaponin A2 (Schidigerasaponin F2) is a steroidal saponin isolated from the rhizomes of Anemarrhena asphodeloides. Anemarrhenasaponin A2 inhibits ADP-induced platelet aggregation .
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-
- HY-N9200
-
|
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Others
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Others
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3-Phenyl-1,2-dihydroacenaphthylene-1,2-diol is a Phenols product that can be isolated from the rhizomes of Musa acuminata .
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-
- HY-125531
-
|
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Others
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Others
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|
Dactylorhin A, a succinate derivative ester, is isolated from rhizomes of Gymnadenia conopsea. Dactylorhin A exhibits moderate inhibitory effects on NO production effects in RAW 264.7 macrophage cells .
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-
- HY-N9016
-
|
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Others
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Others
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8(17),12E,14-Labdatrien-20-oic acid is a Diterpenoids product that can be isolated from the rhizomes of Isodon yuennanensis. .
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-
- HY-N9697
-
|
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Others
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Others
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2-Methoxy-1H-phenalen-1-one is a Phenols product that can be isolated from the rhizomes of Musa acuminata var. .
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-
- HY-N0238
-
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Atractydin
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Insecticide
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Infection
Inflammation/Immunology
|
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Atractylodin (Atractydin) is an orally active active ingredient obtained from the rhizome of Atractylodes lancea and A. chinensis. Atractylodin is a natural insecticide. Atractylodin has anti-inflammatory activity .
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-
- HY-N7576
-
|
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Reactive Oxygen Species (ROS)
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Inflammation/Immunology
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Anemarrhenasaponin Ia, isolated from Anemarrhenae rhizome, inhibits N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide generation. Anemarrhenasaponin Ia is an useful anti-inflammation reagent .
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-
- HY-W998034
-
|
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Others
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Others
|
|
(2,6-Dihydroxy-4-methoxyphenyl)(4-hydroxyphenyl)methanone is a Phenols product that can be isolated from the rhizomes of Anemarrhena asphodeloides BUNGE. .
|
-
- HY-N0203
-
|
ICodonolactone; 8β-Hydroxyasterolide
|
Apoptosis
|
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Atractylenolide III (ICodonolactone) is the main component of Atractylodes rhizome and has the activity of inducing apoptosis in lung cancer cells. Atractylenolide III is an orally active gastroprotective agent .
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-
- HY-N4271
-
|
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Others
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Cardiovascular Disease
|
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Protogracillin is a steroidal saponin isolated from Dioscorea zingiberensis Wright (DZW). Steroidal saponins from DZW rhizomes have the potential to reduce the risk of cardiovascular diseases by anti-thrombotic action .
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-
- HY-N9017
-
|
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Others
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Others
|
|
12E,14-Labdadien-20,8β-olide, a labdane diterpenoid, is a natural product that can be isolated from the rhizomes of Isodon yuennanensis .
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-
- HY-N4243
-
|
|
Others
|
Metabolic Disease
|
|
Neocurdione is a hepatoprotective sesquiterpene isolated from Curcuma zedoaria rhizome. Neocurdione exerts potent effect on D-galactosamine- (D-Gain) and lipopolysaccharide- (LPS) induced acute liver injury in mice .
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-
- HY-N7593
-
|
|
Others
|
Inflammation/Immunology
|
|
Tectoruside is a phenol acid glycoside of the rhizome of Iris dichotoma Pall. Iris dichotoma Pall, a traditional Chinese herbal medicine, has been used in several disorders such as inflammation, throat disorders, asthma and coughs .
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-
- HY-N12035
-
|
|
Others
|
Cancer
|
|
Picropodophyllin-4-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside (compound 17) is a lignan isolated from the roots and rhizomes of Podophyllum sinensis .
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-
- HY-N13708
-
|
|
Others
|
Inflammation/Immunology
|
|
4'-Methoxy-5,6-dihydroxyisoflavone-7-O-β-D-glucopyranoside is an isoflavonoid compound found in the rhizomes of Belamcanda chinensis with anti-inflammatory activity .
|
-
- HY-N10969
-
|
|
Others
|
Others
|
|
(+)-5,7,4'-Trimethoxyafzelechin is a derivative of (+)-Afzelechin HY-N2821. (+)-Afzelechin is an α-glucosidase activity inhibitor. (+)-Afzelechin can be isolated from rhizomes of Bergenia ligulata .
|
-
- HY-N1808
-
|
|
Others
|
Others
|
|
3-Acetoxy-8(17),13E-labdadien-15-oic acid is a Diterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
- HY-N4167
-
|
Galangin 3-methyl ether; 3-Methylgalangin
|
Bacterial
|
Infection
|
|
3-O-Methylgalangin (Galangin 3-methyl ether) is a natural flavonoid compound from the rhizome of Alpinia officinarum (AO) with antibacterial activities, which also inhibits pancreatic lipase .
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-
- HY-N9243
-
|
|
Others
|
Others
|
|
5-Hydroxy-1,7-bis(4-hydroxyphenyl)heptan-3-yl acetate is a Phenols product that can be isolated from the rhizomes of Zingiber officinale .
|
-
- HY-N9298
-
|
|
Others
|
Others
|
|
3,5-Dihydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane is a Phenols product that can be isolated from the rhizomes of Curcuma comosa Roxb. .
|
-
- HY-124474
-
|
|
CCR
|
Neurological Disease
|
|
Procurcumenol, a natural compound that can be isolated from Curcuma zedoaria Rhizomes, possesses neuroprotective and antioxidant activity. Procurcumenol can target CCR5 and has a significant inhibitory effect on platelet aggregation in vitro .
|
-
- HY-N8129
-
|
|
Others
|
Others
|
|
Rhaponticin 6′′-O-gallate is a stilbene glucoside gallate that can be found in rhizome of Rheum undulatum L. Rhaponticin 6′′-O-gallate inhibits nitric oxide production in lipopolysaccharide-activated macrophages .
|
-
- HY-112006
-
|
(+)-alpha-Curcumene
|
Others
|
Others
|
|
(S)-ar-Curcumene ((+)-alpha-Curcumene) is a natural compound. (S)-ar-Curcumene is a constituent of the essential oil that can isolated from the rhizomes of Curcuma aromatica and is an odour component of distantly related corals .
|
-
- HY-N10890
-
|
|
Others
|
Cancer
|
|
Alpinoid D, a diarylheptanoid, can be isolated from the MeOH extract from the rhizomes of Alpinia officinarum Hance. Alpinoid D shows cytotoxic effect against IMR-32 human neuroblastoma cell line .
|
-
- HY-N4119
-
|
|
Cholinesterase (ChE)
|
Neurological Disease
|
|
Neoeriocitrin, isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a potent acetylcholinesterase (AChE) inhibitor .
|
-
- HY-N8859
-
|
16-Hydroxyiridal
|
Others
|
Others
|
|
Isoiridogermanal can be isolated from the extract of rhizomes of Iris tectorum Maxim. Isoiridogermanal is cytotoxic with IC50 values of 11 μM and 23 μM against MCF-7 and C32 cell lines.
|
-
- HY-N0723
-
|
|
Others
|
Metabolic Disease
|
|
Neomangiferin is a natural C-glucosyl xanthone isolated from m the dried rhizome of Anemarrhena asphodeloides. Neomangiferin has significant therapeutic effects on high-fat diet-induced nonalcoholic fatty liver disease (NAFLD) in rats .
|
-
- HY-N8435
-
-
- HY-N4266
-
|
|
Others
|
Cardiovascular Disease
|
|
Vinaginsenoside R8, a triterpenoid glycoside isolated from the rhizomes of Panacis majoris. Vinaginsenoside R8 displays activities against adenosine diphosphate (ADP)-induced platelet aggregation (IC50=25.18 μM) .
|
-
- HY-N9096
-
|
|
Bacterial
|
Neurological Disease
|
|
Gentiside B has neuritogenic activity and induce neurite outgrowth. Gentiside B can be isolated from the root and rhizome of Gentiana rigescens. Gentiana has hepatoprotective, anti-inflammatory, analgesic, antiproliferative and antimicrobial effects .
|
-
- HY-N8047
-
|
|
Others
|
Others
|
|
5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone is a Phenols product that can be isolated from the rhizomes of Curcuma longa L. .
|
-
- HY-N9950
-
|
|
Others
|
Inflammation/Immunology
|
|
α-D-altro-3-Heptulofuranose is a nature product that could be isolated from the rhizomes of Actinidia kolomikta. α-D-altro-3-Heptulofuranose has anti-inflammatory activity .
|
-
- HY-N8997
-
|
|
Others
|
Others
|
|
5-Hydroxy-1,7-diphenyl-4E,6E-dien-3-heptanone is a diarylheptanoid that can be found in dried rhizomes of Alpinia officinarum (Liangjiang) .
|
-
- HY-N9102
-
|
|
Others
|
Others
|
|
1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)hept-6-en-3-ol (Compound 1) is a natural product that can be isolated from rhizomes of Curcuma comosa .
|
-
- HY-N2821
-
|
|
Glycosidase
|
Metabolic Disease
|
|
(+)-Afzelechin, isolated from rhizomes of Bergenia ligulata, is an alpha-glucosidase activity inhibitor with an ID50 (50% inhibition dose) value of 0.13 mM. (+)-Afzelechin can delay the absorption of carbohydrates in food to suppress postprandial hyperglycemia and hyperinsulinemia .
|
-
- HY-N4121
-
|
|
Estrogen Receptor/ERR
Apoptosis
|
Cancer
|
|
Isocurcumenol, an estrogen receptor alpha (ERα) inhibitor isolated from Curcuma zedoaria Rhizomes, possesses anti-tumor acticity, with IC50 values of 99.1μg/mL and 178.2 μg/mL in DLA and KB cells, respectively .
|
-
- HY-N8881
-
|
Jacaranone ethyl ester
|
Others
|
Others
|
|
Ethyl(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)acetate (Jacaranone ethyl ester) is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
- HY-N3821
-
|
|
Others
|
Others
|
|
ent-7α,9-Dihydroxy-15-oxokaur-16-en-19,6β-olide is a Diterpenoids product that can be isolated from the rhizomes of Isodon yuennanensis .
|
-
- HY-W750970
-
|
|
Beta-secretase
Cholinesterase (ChE)
|
Neurological Disease
|
|
2-Acetoxyacorenone (compound 8) is a sesquiterpenoid, which can be isolated from the rhizome of Acorus tatarinowii. 2-Acetoxyacorenone has potent AChE and β-BACE1 inhibitory activity and can be used in the study of Alzheimer's disease .
|
-
- HY-N11919
-
|
|
Others
|
Cancer
|
|
Anticancer agent 149 (compound 3) is an anticancer agent isolated from the rhizome of Dioscorea dioscorea (DM). Anticancer agent 149 exhibits selective cytotoxic activity against MCF-7 cells (IC50=31.41 μM) .
|
-
- HY-N0238R
-
|
Atractydin (Standard)
|
Reference Standards
Others
|
Infection
Inflammation/Immunology
|
|
Atractylodin (Standard) is the analytical standard of Atractylodin. This product is intended for research and analytical applications. Atractylodin (Atractydin) is an orally active active ingredient obtained from the rhizome of Atractylodes lancea and A. chinensis. Atractylodin is a natural insecticide. Atractylodin has anti-inflammatory activity .
|
-
- HY-137957
-
|
|
NO Synthase
COX
|
Inflammation/Immunology
|
|
Longiferone B is a daucane sesquiterpene, that can be isolated from Boesenbergia longiflora rhizomes. Longiferone B shows anti-inflammatory activity against NO release with an IC50 of 21.0 μM. Longiferone B also suppresses the iNOS and COX-2 mRNA expression .
|
-
- HY-W046906R
-
|
|
Reference Standards
Endogenous Metabolite
|
Metabolic Disease
|
|
Timosaponin BII (Standard) is the analytical standard of Timosaponin BII. This product is intended for research and analytical applications. Timosaponin BII (Prototimosaponin A III) is a steroid saponin found in the rhizomes of Anemarrhena asphodeloides. Timosaponin BII has neuronal protective, anti-inflammatory and antioxidant activities .
|
-
- HY-N0812R
-
|
Prototimosaponin A III (Standard)
|
Amyloid-β
Reference Standards
|
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Timosaponin BII (Standard) is the analytical standard of Timosaponin BII. This product is intended for research and analytical applications. Timosaponin BII (Prototimosaponin A III) is a steroid saponin found in the rhizomes of Anemarrhena asphodeloides. Timosaponin BII has neuronal protective, anti-inflammatory and antioxidant activities .
|
-
- HY-N12141
-
|
|
Apoptosis
|
Inflammation/Immunology
|
|
Flaccidoside II inhibits proliferation and induces apoptosis in Malignant peripheral nerve sheath tumors (MPNSTs) cell lines. Flaccidoside II ameliorates collagen-induced arthritis in mice. Flaccidoside II is an active triterpenoid saponin constituent from Anemone flaccida rhizome .
|
-
- HY-N6993
-
|
|
Others
|
Metabolic Disease
|
|
25-O-Methylalisol A is a protostane triterpenoids isolated from Alisma orientale. The dried rhizomes of the aquatic plant Alisma orientale known as Rhizoma Alismatis is a common traditional Chinese medicine used for diuretic, anti-inflammatory, and hypolipidemic purposes, as well as the treatment of diabetes .
|
-
- HY-N9187
-
|
|
Others
|
Others
|
|
1α,4β,10β-Trihydroxyguaia-2,11(13)-dien-12,6α-olide is a Sesquiterpenoids product that can be isolated from the rhizomes of Alisma orientale .
|
-
- HY-100599R
-
-
- HY-N13136
-
|
|
Others
|
Cancer
|
|
Timosaponin D, a natural steroid saponin, can be obtained from the rhizome of Anemarrhena asphodeloides. The IC50 values of Timosaponin D against HepG2 and SGC7901 cells are 43.90 and 57.90 μM, respectively. Timosaponin D can be used in anticancer research .
|
-
- HY-N9018
-
|
|
Others
|
Others
|
|
4-(6-Methyl-4-oxohept-5-en-2-yl)cyclohex-2-en-1-one is a Sesquiterpenoids product that can be isolated from the rhizomes of Curcuma longa .
|
-
- HY-N0203R
-
|
ICodonolactone (Standard); 8β-Hydroxyasterolide (Standard)
|
Reference Standards
Apoptosis
|
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Atractylenolide III (Standard) is the analytical standard of Atractylenolide III. This product is intended for research and analytical applications. Atractylenolide III (ICodonolactone) is the main component of Atractylodes rhizome and has the activity of inducing apoptosis in lung cancer cells. Atractylenolide III is an orally active gastroprotective agent .
|
-
- HY-N7619
-
|
Purpuroxanthin
|
HIV
|
Infection
Inflammation/Immunology
Cancer
|
|
Xanthopurpurin is an orally active anthraquinone glycoside. Xanthopurpurin can be isolated from the rhizome of Rubia akane. Xanthopurpurin has antiviral effects against rotavirus and HIV. Xanthopurpurin has a strong inhibitory effect on collagen-induced platelet aggregation. Xanthopurpurin prevents peanut allergy .
|
-
- HY-N7619R
-
|
|
HIV
|
Infection
Inflammation/Immunology
Cancer
|
|
Xanthopurpurin is an orally active anthraquinone glycoside. Xanthopurpurin can be isolated from the rhizome of Rubia akane. Xanthopurpurin has antiviral effects against rotavirus and HIV. Xanthopurpurin has a strong inhibitory effect on collagen-induced platelet aggregation. Xanthopurpurin prevents peanut allergy .
|
-
- HY-N8989
-
|
|
Lipase
|
Metabolic Disease
|
|
(1,5E,11E)-Tridecatriene-7,9-diyne-3,4-diacetate, isolated from the ethanol extract of Atractylodes lancea rhizome, displays significant lipase inhibition with an IC50 value of 23.9 µg/mL. Antiobesity Effect .
|
-
- HY-N15714
-
|
|
Drug Derivative
|
Cancer
|
|
Acoraminol A is one of the stereoisomers of phenylpropanoids, the other of which is Acoraminol B (HY-N15715), which can be isolated from the methanol extract of the rhizome of Acorus tatarinowii. Acoraminol A has weak cytotoxic effects on several human tumor cell lines (IC50>30 μM) .
|
-
- HY-N9257
-
|
|
Others
|
Neurological Disease
|
|
8-Hydroxypinoresinol4,4'-di-O-β-D-glucopyranoside (Compound 7) is a compound derived from roots and rhizomes. 8-Hydroxypinoresinol4,4'-di-O-β-D-glucopyranoside could prevent neurotoxicity in PC12 cells .
|
-
- HY-N4119R
-
|
|
Reference Standards
Cholinesterase (ChE)
|
Neurological Disease
|
|
Neoeriocitrin (Standard) is the analytical standard of Neoeriocitrin. This product is intended for research and analytical applications. Neoeriocitrin, isolated from Drynaria Rhizome,?shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a potent acetylcholinesterase (AChE) inhibitor .
|
-
- HY-N0201
-
|
|
TNF Receptor
Toll-like Receptor (TLR)
JAK
STAT
|
Cancer
|
|
Atractylenolide I is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties. Atractylenolide I reduces protein levels of phosphorylated JAK2 and STAT3 in A375 cells, and acts as a TLR4-antagonizing agent.
|
-
- HY-N15715
-
|
|
Drug Derivative
|
Cancer
|
|
Acoraminol B is one of the stereoisomers of phenylpropanoids, the other of which is Acoraminol A (HY-N15714), which can be isolated from the methanol extract of the rhizome of Acorus tatarinowii. Acoraminol B has weak cytotoxic effects on several human tumor cell lines (IC50>30 μM) .
|
-
- HY-N0723R
-
|
|
Reference Standards
Others
|
Metabolic Disease
|
|
Neomangiferin (Standard) is the analytical standard of Neomangiferin. This product is intended for research and analytical applications. Neomangiferin is a natural C-glucosyl xanthone isolated from m the dried rhizome of Anemarrhena asphodeloides. Neomangiferin has significant therapeutic effects on high-fat diet-induced nonalcoholic fatty liver disease (NAFLD) in rats .
|
-
- HY-122938
-
|
(2S,3R)-Ceplignan
|
Others
|
Others
|
|
Ceplignan ((2S,3R)-Ceplignan) is a neogenic lignan, which can be isolated from the rhizomes of Acorus tatarinowii Schott. (2S,3R)-Ceplignan and (2R,3S)-ceplignan are two isomers of Ceplignan .
|
-
- HY-N6872
-
|
|
JNK
Akt
Apoptosis
Autophagy
Reactive Oxygen Species (ROS)
|
Cancer
|
|
Actein, a triterpene glycoside, shows an inhibitory effect on cancer cells, which is isolated from the rhizomes of Cimicifuga foetida. Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in bladder cancer. Actein has little toxicity in vivo .
|
-
- HY-N8448
-
|
Macroantoin F
|
RSV
|
Infection
|
|
3,4-Di-O-caffeoyl quinic acid methyl ester (Macroantoin F) is a dicaffeoyl derivative isolated from the rhizome of Elephantopus scaber Linn. 3,4-Di-O-caffeoyl quinic acid methyl ester exhibited in vitro antiviral activity against respiratory syncytial virus (RSV) with an IC50 value of 0.78 μg/mL .
|
-
- HY-N2790
-
|
9,13α-Epidioxy-8(14)-abieten-18-oic acid
|
Others
|
Others
|
|
9α,13α-Epidioxyabiet-8(14)-en-18-oic acid (9,13α-Epidioxy-8(14)-abieten-18-oic acid) is a Sesquiterpenoids product that can be isolated from the rhizomes of Carpesium abrotanoides .
|
-
- HY-N3348
-
|
|
Fungal
|
Infection
Inflammation/Immunology
|
|
Lyoniside is a lignan glycoside with antioxidant, allelopathic and antifungal activities, which can be isolated from the rhizomes and stems of bilberry (Vaccinium myrtillus L.). Lyoniside exhibits radical scavenging properties with an IC50 value of 23 μg/mL in DPPH assay. Lyoniside inhibits the mycelial growth of Fusarium oxysporum and Mucor hiemalis at 50 μg/mL with inhibitory rates of 78% and 80%, respectively .
|
-
- HY-N11894
-
|
|
Others
|
Others
|
|
1,3,6-Trihydroxy-2-methyl-9,10-anthraquinone-3-O-(6'-O-acetyl)-beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside ( Compound 20) is a quinone compound that can be isolated from the roots and rhizomes of Madder .
|
-
- HY-134635
-
|
|
Bacterial
Fungal
HIV
|
Infection
Neurological Disease
Cancer
|
|
Dehydrozingerone (Compound 10), a structural half analogue of Curcumin (HY-N0005), is a phenolic compound with antibacterial, anticancer, antioxidant, anti-Alzheimer’s and antifungal activity, which is isolated from ginger (Zingiber officinale) rhizomes. Dehydrozingerone shows moderate inhibitory activities on the secretion of HBsAg in HepG 2 cells with an IC50 value of 0.50 mM .
|
-
- HY-N9093
-
|
|
Others
|
Inflammation/Immunology
Cancer
|
|
(3R,5R)-3,5-Diacetoxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane, a diarylheptanoid from the rhizomes of Curcuma kwangsiensis, possesses a variety of biological and pharmacological activities including antioxidant, antihepa totoxic, anti-inflammatory, antiproliferative, antiemetic, and antitumor activities .
|
-
- HY-107315
-
|
|
HBV
Apoptosis
|
Infection
Cancer
|
|
Alisol F 24-acetate is a triterpene compound that can be isolated from the rhizomes of Alisma orientalis. Alisol F 24-acetate inhibits the secretion of HBV surface antigen HBsAg and HBeAg with IC50 values of 7.7 µM and 5.1 µM. Alisol F 24-acetate has proapoptotic activity and can be used for cancer research .
|
-
- HY-N0447R
-
|
|
Reference Standards
TRP Channel
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
|
8-Gingerol (Standard) is the analytical standard of 8-Gingerol. This product is intended for research and analytical applications. 8-Gingerol, found in the rhizomes of ginger (Z. officinale) with oral bioavailability, activates TRPV1, with an EC50 of 5.0 μM. 8-Gingerol inhibits COX-2, and inhibits the growth of H. pylori in vitro .
|
-
- HY-N0120
-
|
(E/Z)-Piceid
|
Others
|
Inflammation/Immunology
|
|
(E/Z)-Polydatin ((E/Z)-Piceid) is the E/Z mixture of Polydatin (HY-N0120A). Polydatin is a monocrystalline compound originally isolated from the root and rhizome of Polygonum cuspidatum. (E/Z)-Polydatin has anti-platelet aggregation, anti-oxidative action of low-density lipoprotein (LDL), cardioprotective activity, anti-inflammatory and immune-regulating functions .
|
-
- HY-N0448R
-
|
|
Reference Standards
Others
|
Inflammation/Immunology
Cancer
|
|
10-Gingerol (Standard) is the analytical standard of 10-Gingerol. This product is intended for research and analytical applications. 10-Gingerol is a major pungent constituent in the ginger oleoresin from fresh rhizome, with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM .
|
-
- HY-N6872R
-
|
|
Reference Standards
JNK
Akt
Apoptosis
Autophagy
Reactive Oxygen Species (ROS)
|
Cancer
|
|
Actein (Standard) is the analytical standard of Actein. This product is intended for research and analytical applications. Actein, a triterpene glycoside, shows an inhibitory effect on cancer cells, which is isolated from the rhizomes of Cimicifuga foetida. Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in bladder cancer. Actein has little toxicity in vivo .
|
-
- HY-133865
-
|
|
Interleukin Related
|
Metabolic Disease
Inflammation/Immunology
|
|
Diacetoxy-6-gingerdiol is a gingerol isolated with anti-inflammatory and antioxidant effects, which is found in the dichloromethane extract of rhizomes of ginger (Zingiber officinale Roscoe). Diacetoxy-6-gingerdiol protects the extracellular matrix of nucleus pulposus cells and ameliorates intervertebral disc degeneration by inhibiting the IL-1β-mediated NLRP3 pathway .
|
-
- HY-B0510CR
-
|
|
Reference Standards
Antifolate
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Actein (Standard) is the analytical standard of Actein. This product is intended for research and analytical applications. Actein, a triterpene glycoside, shows an inhibitory effect on cancer cells, which is isolated from the rhizomes of Cimicifuga foetida. Actein suppresses cell proliferation, induces autophagy and apoptosis through promoting ROS/JNK activation, and blunting AKT pathway in bladder cancer. Actein has little toxicity in vivo .
|
-
- HY-N0201R
-
|
|
TNF Receptor
Reference Standards
Toll-like Receptor (TLR)
JAK
STAT
|
Cancer
|
|
Atractylenolide I (Standard) is the analytical standard of Atractylenolide I. This product is intended for research and analytical applications. Atractylenolide I is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties. Atractylenolide I reduces protein levels of phosphorylated JAK2 and STAT3 in A375 cells, and acts as a TLR4-antagonizing agent.
|
-
- HY-N6018
-
|
|
Caspase
TNF Receptor
SOD
Reactive Oxygen Species (ROS)
|
Inflammation/Immunology
Cancer
|
|
Beta-Eudesmol has anticancer and anti-inflammatory activities. Beta-Eudesmol can induce apoptosis. Beta-Eudesmol is a neostigmine antagonist. Beta-Eudesmol can antagonize neostigmine-induced neuromuscular failure. Beta-Eudesmol can be used in the study of sepsis diseases. Beta-Eudesmol is a sesquiterpene-like compound that can be extracted from the rhizome of Atractylodes lancea .
|
-
- HY-134635R
-
|
|
Bacterial
Fungal
HIV
|
Infection
Neurological Disease
Cancer
|
|
Dehydrozingerone (Standard) is the analytical standard of Dehydrozingerone. This product is intended for research and analytical applications. Dehydrozingerone (Compound 10), a structural half analogue of Curcumin (HY-N0005), is a phenolic compound with antibacterial, anticancer, antioxidant, anti-Alzheimer’s and antifungal activity, which is isolated from ginger (Zingiber officinale) rhizomes. Dehydrozingerone shows moderate inhibitory activities on the secretion of HBsAg in HepG 2 cells with an IC50 value of 0.50 mM .
|
-
- HY-N0988
-
|
|
Others
|
Cancer
|
|
1β,4β,7α-Trihydroxyeudesmane (compound 4) is a nature product that could be isolated from the rhizomes of Homalomena occulta. 1β,4β,7α-Trihydroxyeudesmane has antiproliferative active. 1β,4β,7α-Trihydroxyeudesmane can be used in research of cancer .
|
-
- HY-N0997
-
|
|
NO Synthase
|
Inflammation/Immunology
Cancer
|
|
(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one (compound7) is a nature product isolated from rhizomes of Curcuma kwangsiensis. (6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one has inhibitory effect on NO production induced by LPS in macrophages with an IC50 value of 8.93 μM .
|
-
- HY-N6924
-
|
|
HIV
|
Infection
Metabolic Disease
Cancer
|
|
Zingibroside R1 is dammaranae-type triterpenoid saponin, isolated from rhizomes, taproots, and lateral roots of Panax japonicas C. A. Meyer, shows excellent anti-tumor effects as well as anti-angiogenic activity .
Zingibroside R1 possesses some anti-HIV-1 activity.
Zingibroside R1 has inhibitory effects on the 2-deoxy-D-glucose (2-DG) uptake by EAT cells (IC50=91.3 μM) .
|
-
- HY-W009732
-
|
Sinapic acid
|
HDAC
Angiotensin-converting Enzyme (ACE)
Reactive Oxygen Species (ROS)
Apoptosis
|
Cardiovascular Disease
Metabolic Disease
Cancer
|
|
Sinapinic acid (Sinapic acid) is a phenolic compound isolated from Hydnophytum formicarum Jack. Rhizome, acts as an inhibitor of HDAC, with an IC50 of 2.27 mM , and also inhibits ACE-I activity . Sinapinic acid posssess potent anti-tumor activity, induces apoptosis of tumor cells . Sinapinic acid shows antioxidant and antidiabetic activities . Sinapinic acid reduces total cholesterol, triglyceride, and HOMA-IR index, and also normalizes some serum parameters of antioxidative abilities and oxidative damage in ovariectomized rats .
|
-
- HY-W009732R
-
|
|
HDAC
Angiotensin-converting Enzyme (ACE)
Reactive Oxygen Species (ROS)
Apoptosis
|
Cardiovascular Disease
Metabolic Disease
Cancer
|
|
Sinapinic acid (Sinapic acid) is a phenolic compound isolated from Hydnophytum formicarum Jack. Rhizome, acts as an inhibitor of HDAC, with an IC50 of 2.27 mM , and also inhibits ACE-I activity . Sinapinic acid posssess potent anti-tumor activity, induces apoptosis of tumor cells . Sinapinic acid shows antioxidant and antidiabetic activities . Sinapinic acid reduces total cholesterol, triglyceride, and HOMA-IR index, and also normalizes some serum parameters of antioxidative abilities and oxidative damage in ovariectomized rats .
|
-
- HY-Y0121
-
|
|
Parasite
VEGFR
Apoptosis
|
Cardiovascular Disease
Cancer
|
|
Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
|
-
- HY-N16450
-
|
|
NO Synthase
COX
Interleukin Related
TNF Receptor
p38 MAPK
JNK
NF-κB
|
Inflammation/Immunology
|
|
Cnidilide is a natural product of alkylphthalein. Cnidilide can be isolated from the rhizomes of Cnidium officinale. Cnidilide reduces the production of NO and PGE2 by inhibiting the expression of iNOS and COX-2 induced by LPS (HY-D1056). Cnidilide can inhibit pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. Cnidilide can specifically inhibit the phosphorylation of p38 MAPK and JNK, as well as the activation of downstream kinase MSK-1. Cnidilide blocks the signaling pathway by inhibiting the transcriptional activity of AP-1 and NF-κB. can be used for research on inflammation conditions .
|
-
- HY-N3584
-
|
Chonglou Saponin VII
|
Akt
p38 MAPK
P-glycoprotein
Bcl-2 Family
Caspase
PARP
Autophagy
Apoptosis
|
Cancer
|
|
Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia .
|
-
- HY-N0853
-
|
|
AMPK
Acetyl-CoA Carboxylase
PPAR
MMP
Interleukin Related
|
Infection
Cardiovascular Disease
Metabolic Disease
Cancer
|
|
Alisol A is an orally active tetracyclic triterpenoid compound of the prototerpane type. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPARα, inhibits MMP-2/-9, decreases inflammatory cytokine expression (IL-1β, IL-6, IL-8). Alisol A has anti-tumor activity against breast cancer and colorectal cancer. Alisol A has anti-obesity and anti-atherosclerotic activities. Alisol A can be used in the research of hepatitis B, breast cancer, colorectal cancer, atherosclerosis, and obesity .
|
-
- HY-Y0121R
-
|
|
Reference Standards
Parasite
VEGFR
Apoptosis
|
Cardiovascular Disease
Cancer
|
|
Ethyl cinnamate (Standard) is the analytical standard of Ethyl cinnamate. This product is intended for research and analytical applications. Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
|
-
- HY-Y0121S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Ethyl cinnamate-d7 is deuterated labeled Ethyl cinnamate (HY-Y0121). Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
|
-
- HY-N0447
-
|
|
TRP Channel
Bacterial
Apoptosis
Autophagy
STAT
PERK
EGFR
PI3K
Akt
mTOR
Caspase
MMP
|
Infection
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
|
8-Gingerol can be found in the rhizome of ginger (Z. officinale) and has oral bioactivity. It activates TRPV1, with an EC50 value of 5.0 µM. 8-Gingerol inhibits COX-2 and also suppresses the growth of H. pylori in vitro. Additionally, 8-Gingerol exhibits anticancer, antioxidant, and anti-inflammatory properties by inhibiting the epidermal growth factor receptor (EGFR) and modulating its downstream STAT3/ERK pathway to suppress the proliferation, migration, and invasion of colorectal cancer cells. 8-Gingerol also exerts immunosuppressive effects by inhibiting oxidative stress, inducing cell cycle arrest, promoting apoptosis, and regulating autophagy. Furthermore, 8-Gingerol has cardioprotective effects. 8-Gingerol is promising for research in the fields of cancer, infection, immunosuppression, and cardiovascular diseases.
|
-
- HY-N3584R
-
|
Chonglou Saponin VII (Standard)
|
Reference Standards
Akt
p38 MAPK
P-glycoprotein
Bcl-2 Family
Caspase
PARP
Autophagy
Apoptosis
|
Cancer
|
|
Paris saponin VII (Standard) is the analytical standard of Paris saponin VII. This product is intended for research and analytical applications. Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia .
|
-
- HY-162802
-
|
|
Apoptosis
PI3K
Akt
PARP
CDK
|
Cancer
|
|
PI3K/AKT-IN-4 (compound 3) is a diterpenoid that can be isolated from the roots and rhizomes of Salvia castanea Dielsf. PI3K/AKT-IN-4 has antitumor activity, inhibiting cell viability and proliferation (IC50=4.72 μM) and promoting apoptosis by blocking the G0/G1 phase of the Hep3B cell cycle, inducing mitochondrial dysfunction and oxidative stress. In addition, PI3K/AKT-IN-4 inhibits hepatocellular carcinoma by inhibiting the PI3K-Akt signaling pathway and binding to PARP1 and CDK2 targets .
|
-
- HY-16958R
-
|
|
Antibiotic
Dimethylargininase (DDAH)
Reference Standards
|
Inflammation/Immunology
|
|
Paris saponin VII (Standard) is the analytical standard of Paris saponin VII. This product is intended for research and analytical applications. Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia .
|
-
- HY-N0853R
-
|
|
Reference Standards
AMPK
Acetyl-CoA Carboxylase
PPAR
MMP
Interleukin Related
|
Infection
Cardiovascular Disease
Metabolic Disease
Cancer
|
|
Alisol A (Standard) is the analytical standard of Alisol A (HY-N0853). This product is intended for research and analytical applications. Alisol A is an orally active tetracyclic triterpenoid compound of the prototerpane type. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPARα, inhibits MMP-2/-9, decreases inflammatory cytokine expression (IL-1β, IL-6, IL-8). Alisol A has anti-tumor activity against breast cancer and colorectal cancer. Alisol A has anti-obesity and anti-atherosclerotic activities. Alisol A can be used in the research of hepatitis B, breast cancer, colorectal cancer, atherosclerosis, and obesity .
|
-
- HY-N0448
-
|
|
AMPK
Reactive Oxygen Species (ROS)
Akt
PI3K
Interleukin Related
TNF Receptor
Apoptosis
|
Inflammation/Immunology
Cancer
|
|
10-Gingerol is an AMPK agonist, which is found in the ginger oleoresin from fresh rhizome with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol suppresses neointimal hyperplasia and inhibits vascular smooth muscle cell proliferation. 10-Gingerol exhibits substantial scavenging activities with an IC50 value of 10.47 μM against DPPH radical, an IC50 value of 1.68 μM against superoxide radical and an IC50 value of 1.35 μM against hydroxyl radical. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM. 10-Gingerol suppresses the proliferation, migration, invasion, and induced apoptosis through targeting the PI3K/Akt signaling pathway in MDA-MB-231/IR cells. 10-Gingerol is promising for research of ulcerative colitis .
|
-
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
- HY-N1573
-
-
- HY-N9231
-
-
- HY-N8689
-
-
- HY-N12363
-
-
- HY-N9201
-
-
- HY-125100
-
-
- HY-N2505
-
-
- HY-N12029
-
-
- HY-N2401
-
-
- HY-N4174
-
-
- HY-N1304
-
-
- HY-N4306
-
-
- HY-N9691
-
-
- HY-N11665
-
-
- HY-N3834
-
-
- HY-N7960
-
-
- HY-N1572
-
-
- HY-123080
-
-
- HY-N8262
-
-
- HY-N8652
-
-
- HY-N12150
-
-
- HY-N9177
-
-
- HY-N15724
-
-
- HY-N8951
-
-
- HY-133223
-
-
- HY-N7798
-
-
- HY-W015879R
-
-
- HY-N5108
-
-
- HY-128683
-
-
- HY-N10694
-
-
- HY-N8990
-
-
- HY-N4062
-
-
- HY-N0812
-
-
- HY-N12215
-
-
- HY-N10047
-
-
- HY-N2762
-
-
- HY-N7614
-
-
- HY-N9200
-
-
- HY-125531
-
-
- HY-N9016
-
-
- HY-N9697
-
-
- HY-N0238
-
-
- HY-N7576
-
-
- HY-W998034
-
-
- HY-N0203
-
-
- HY-N4271
-
-
- HY-N9017
-
-
- HY-N4243
-
-
- HY-N7593
-
-
- HY-N12035
-
-
- HY-N13708
-
-
- HY-N10969
-
-
- HY-N1808
-
-
- HY-N4167
-
-
- HY-N9243
-
-
- HY-N9298
-
-
- HY-124474
-
-
- HY-N8129
-
-
- HY-N10890
-
-
- HY-N4119
-
-
- HY-N8859
-
-
- HY-N0723
-
-
- HY-N4266
-
-
- HY-N9096
-
-
- HY-N8047
-
-
- HY-N9950
-
-
- HY-N8997
-
-
- HY-N2821
-
-
- HY-N4121
-
-
- HY-N8881
-
-
- HY-N3821
-
-
- HY-W750970
-
-
- HY-N11919
-
-
- HY-N0238R
-
-
- HY-137957
-
-
- HY-W046906R
-
-
- HY-N0812R
-
-
- HY-N12141
-
-
- HY-N6993
-
-
- HY-N9187
-
-
- HY-100599R
-
-
- HY-N13136
-
-
- HY-N9018
-
-
- HY-N0203R
-
-
- HY-N7619
-
-
- HY-N7619R
-
-
- HY-N8989
-
-
- HY-N15714
-
-
- HY-N9257
-
-
- HY-N4119R
-
-
- HY-N0201
-
-
- HY-N15715
-
-
- HY-N0723R
-
-
- HY-122938
-
-
- HY-N6872
-
-
- HY-N8448
-
|
Macroantoin F
|
Source classification
Phenols
Polyphenols
Amorpha fruticosaL.
Plants
Compositae
|
RSV
|
|
3,4-Di-O-caffeoyl quinic acid methyl ester (Macroantoin F) is a dicaffeoyl derivative isolated from the rhizome of Elephantopus scaber Linn. 3,4-Di-O-caffeoyl quinic acid methyl ester exhibited in vitro antiviral activity against respiratory syncytial virus (RSV) with an IC50 value of 0.78 μg/mL .
|
-
- HY-N2790
-
-
- HY-N3348
-
-
- HY-N11894
-
-
- HY-N9093
-
|
|
Source classification
Phenols
Curcuma kwangsiensis S. K. Lee & C. F. Liang
Plants
Zingiberaceae
|
Others
|
|
(3R,5R)-3,5-Diacetoxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane, a diarylheptanoid from the rhizomes of Curcuma kwangsiensis, possesses a variety of biological and pharmacological activities including antioxidant, antihepa totoxic, anti-inflammatory, antiproliferative, antiemetic, and antitumor activities .
|
-
- HY-107315
-
-
- HY-N0447R
-
-
- HY-N0120
-
-
- HY-N0448R
-
-
- HY-N6872R
-
-
- HY-133865
-
-
- HY-N0201R
-
-
- HY-N6018
-
-
- HY-N0988
-
-
- HY-N0997
-
-
- HY-N6924
-
-
- HY-W009732
-
-
- HY-W009732R
-
-
- HY-Y0121
-
-
- HY-N16450
-
|
|
Natural Products
Source classification
Plants
|
NO Synthase
COX
Interleukin Related
TNF Receptor
p38 MAPK
JNK
NF-κB
|
|
Cnidilide is a natural product of alkylphthalein. Cnidilide can be isolated from the rhizomes of Cnidium officinale. Cnidilide reduces the production of NO and PGE2 by inhibiting the expression of iNOS and COX-2 induced by LPS (HY-D1056). Cnidilide can inhibit pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. Cnidilide can specifically inhibit the phosphorylation of p38 MAPK and JNK, as well as the activation of downstream kinase MSK-1. Cnidilide blocks the signaling pathway by inhibiting the transcriptional activity of AP-1 and NF-κB. can be used for research on inflammation conditions .
|
-
- HY-N3584
-
-
- HY-N0853
-
|
|
Triterpenes
Alisma plantago-aquatica Linn.
Classification of Application Fields
Terpenoids
Source classification
Other Diseases
Alismataceae
Plants
Disease Research Fields
|
AMPK
Acetyl-CoA Carboxylase
PPAR
MMP
Interleukin Related
|
|
Alisol A is an orally active tetracyclic triterpenoid compound of the prototerpane type. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPARα, inhibits MMP-2/-9, decreases inflammatory cytokine expression (IL-1β, IL-6, IL-8). Alisol A has anti-tumor activity against breast cancer and colorectal cancer. Alisol A has anti-obesity and anti-atherosclerotic activities. Alisol A can be used in the research of hepatitis B, breast cancer, colorectal cancer, atherosclerosis, and obesity .
|
-
- HY-Y0121R
-
|
|
Kaempferia galanga L.
Microorganisms
Source classification
Other Phenylpropanoids
Phenylpropanoids
Plants
Zingiberaceae
|
Reference Standards
Parasite
VEGFR
Apoptosis
|
|
Ethyl cinnamate (Standard) is the analytical standard of Ethyl cinnamate. This product is intended for research and analytical applications. Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
|
-
- HY-N0447
-
|
|
Zingiber officinale Roscoe
Monophenols
Classification of Application Fields
Source classification
Phenols
Plants
Inflammation/Immunology
Disease Research Fields
Zingiberaceae
Cancer
|
TRP Channel
Bacterial
Apoptosis
Autophagy
STAT
PERK
EGFR
PI3K
Akt
mTOR
Caspase
MMP
|
|
8-Gingerol can be found in the rhizome of ginger (Z. officinale) and has oral bioactivity. It activates TRPV1, with an EC50 value of 5.0 µM. 8-Gingerol inhibits COX-2 and also suppresses the growth of H. pylori in vitro. Additionally, 8-Gingerol exhibits anticancer, antioxidant, and anti-inflammatory properties by inhibiting the epidermal growth factor receptor (EGFR) and modulating its downstream STAT3/ERK pathway to suppress the proliferation, migration, and invasion of colorectal cancer cells. 8-Gingerol also exerts immunosuppressive effects by inhibiting oxidative stress, inducing cell cycle arrest, promoting apoptosis, and regulating autophagy. Furthermore, 8-Gingerol has cardioprotective effects. 8-Gingerol is promising for research in the fields of cancer, infection, immunosuppression, and cardiovascular diseases.
|
-
- HY-N3584R
-
|
Chonglou Saponin VII (Standard)
|
Liliaceae
Source classification
Trillium tschonoskii Maxim.
Plants
Steroids
|
Reference Standards
Akt
p38 MAPK
P-glycoprotein
Bcl-2 Family
Caspase
PARP
Autophagy
Apoptosis
|
|
Paris saponin VII (Standard) is the analytical standard of Paris saponin VII. This product is intended for research and analytical applications. Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia .
|
-
- HY-N0853R
-
|
|
Triterpenes
Alisma plantago-aquatica Linn.
Terpenoids
Source classification
Alismataceae
Plants
|
Reference Standards
AMPK
Acetyl-CoA Carboxylase
PPAR
MMP
Interleukin Related
|
|
Alisol A (Standard) is the analytical standard of Alisol A (HY-N0853). This product is intended for research and analytical applications. Alisol A is an orally active tetracyclic triterpenoid compound of the prototerpane type. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPARα, inhibits MMP-2/-9, decreases inflammatory cytokine expression (IL-1β, IL-6, IL-8). Alisol A has anti-tumor activity against breast cancer and colorectal cancer. Alisol A has anti-obesity and anti-atherosclerotic activities. Alisol A can be used in the research of hepatitis B, breast cancer, colorectal cancer, atherosclerosis, and obesity .
|
-
- HY-N0448
-
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W015879S
-
|
|
|
2-Heptanol-d5 is deuterated labeled 2-Heptanol (HY-W015879). 2-Heptanol is one of the chemical compounds identified in turmeric and turmeric rhizome essential oil. 2-Heptanol can speed up amino acid metabolism and slow down membrane transport, exhibiting antibacterial activity. The rhizome essential oil has good antibacterial and antioxidant properties .
|
-
-
- HY-Y0121S1
-
|
|
|
Ethyl cinnamate-d7 is deuterated labeled Ethyl cinnamate (HY-Y0121). Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
|
-
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