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Results for "

rat lymphocyte

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Bacterial (1) Calcium Channel (1) CD2 (2) Cytochrome P450 (1) EGFR (2) Fungal (1) Integrin (2) Na+/H+ Exchanger (NHE) (1) Nucleoside Antimetabolite/Analog (2) Potassium Channel (1) Prostaglandin Receptor (2) Transmembrane Glycoprotein (1)
By Research Areas:	Cancer (7) Cardiovascular Disease (1) Endocrinology (2) Infection (1) Inflammation/Immunology (8) Metabolic Disease (1)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Targets Recommended: LAG-3 CTLA-4

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100302

FR183998 free base	Na+/H+ Exchanger (NHE)	Cardiovascular Disease Inflammation/Immunology
FR183998 free base is a potent Na ⁺/H ⁺-exchange inhibitor, with IC₅₀s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pH_i change in rat lymphocytes, rat and human platelets, respectively.

HY-16210

Forodesine Maximum Cited Publications 15 Publications Verification BCX-1777; Immucillin-H	Nucleoside Antimetabolite/Analog Apoptosis	Cancer
Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC₅₀ values ranging from 0.48 to 1.57 nM for *human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte* proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels .

HY-16209

Forodesine hydrochloride Maximum Cited Publications 15 Publications Verification BCX-1777 hydrochloride; Immucillin-H hydrochloride	Nucleoside Antimetabolite/Analog Apoptosis	Cancer
Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC₅₀ values ranging from 0.48 to 1.57 nM for *human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte* proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels .

HY-B0885

Econazole 5 Publications Verification (±)-Econazol	Fungal Bacterial Calcium Channel Cytochrome P450	Infection Metabolic Disease
Econazole ((±)-Econazol) is an orally active imidazole antifungal agent, as well as a cytochrome P-450 inhibitor and a blocker of calcium and manganese ion uptake. Econazole is active against a variety of fungi and some Gram-positive bacteria, but has no significant activity against Gram-negative bacteria. Econazole can inhibit the synthesis of prostaglandins and can also induce liver damage .

HY-P990288

Anti-Mouse CD18 Antibody (M18/2)	Integrin Transmembrane Glycoprotein	Inflammation/Immunology
Anti-Mouse CD18 Antibody (M18/2) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse CD18. Anti-Mouse CD18 Antibody (M18/2) can neutralize lymphocyte function-associated antigen 1 (LFA-1). Anti-Mouse CD18 Antibody (M18/2) can be used for the researches of immunology, such as heart transplantation .

HY-15342

Timapiprant 4 Publications Verification OC000459	Prostaglandin Receptor	Inflammation/Immunology Endocrinology
Timapiprant (OC000459) is a potent, selective, and orally active D prostanoid receptor 2 (DP₂, also known as CRTH2) antagonist. Timapiprant (OC000459) potently displaces [ ³H] PGD2 from human recombinant DP₂ (K_i=13 nM), rat recombinant DP₂ (K_i=3 nM), and human native DP₂ (K_i=4 nM). Timapiprant (OC000459) inhibits mast cell activation of Th2 lymphocytes and eosinophils .

HY-P990286

Anti-Rat CD2 Antibody (OX-34)	CD2	Inflammation/Immunology Cancer
Anti-Rat CD2 Antibody (OX-34) is mouse-derived IgG2a κ type antibody inhibitor, targeting to rat CD2. Anti-Rat CD2 Antibody (OX-34) can block CD2 and inhibit the mixed lymphocyte reaction. Anti-Rat CD2 Antibody (OX-34) can be used for the researches of cancer, inflammation and immunology, such as RNK-16 tumor and arthritis .

HY-P5742

ELAAWCRWGFLLALLPPGIAG	EGFR	Cancer
ELAAWCRWGFLLALLPPGIAG (P5) is derived from rat HER2/neu protein with 21 amino acid length (aa 5-25). ELAAWCRWGFLLALLPPGIAG can induce cytotoxic T lymphocyte (CTL) responses in mice bearing HER2-positive tumours .

HY-P5742A

ELAAWCRWGFLLALLPPGIAG TFA	EGFR	Cancer
ELAAWCRWGFLLALLPPGIAG TFA (P5) is derived from rat HER2/neu protein with 21 amino acid length (aa 5-25). ELAAWCRWGFLLALLPPGIAG TFA can induce cytotoxic T lymphocyte (CTL) responses in mice bearing HER2-positive tumours .

HY-P3071

ShK toxin Stichodactyla helianthus neurotoxin	Potassium Channel	Inflammation/Immunology
ShK toxin blocks voltage-dependent potassium channel (K_v1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin suppresses K+ currents in cultured rat dorsal root ganglion neurons. ShK toxin also inhibits T lymphocyte proliferation .

HY-15342A

Timapiprant sodium 4 Publications Verification OC000459 sodium	Prostaglandin Receptor	Inflammation/Immunology Endocrinology
Timapiprant sodium (OC000459 sodium) is a potent, selective, and orally active D prostanoid receptor 2 (DP₂, also known as CRTH2) antagonist. Timapiprant sodium (OC000459 sodium) potently displaces [ ³H] PGD2 from human recombinant DP₂ (K_i=13 nM), rat recombinant DP₂ (K_i=3 nM), and human native DP₂ (K_i=4 nM). Timapiprant sodium (OC000459 sodium) inhibits mast cell activation of Th2 lymphocytes and eosinophils .

HY-P99120

Anti-Mouse CD11a Antibody (FD441.8)	Integrin	Inflammation/Immunology Cancer
Anti-Mouse CD11a Antibody (FD441.8) is an anti-mouse CD11a IgG2b antibody inhibitor derived from the host Rat. Anti-Mouse CD11a Antibody (FD441.8) can neutralize CD11a also known as LFA-1α (lymphocyte function-associated antigen 1 alpha). Anti-Mouse CD11a Antibody (FD441.8) can be used for the researches of inflammation, immunology and cancer, such as transplant and leukemia .

HY-P991543

BTI-322	CD2	Inflammation/Immunology Cancer
BTI-322 is a rat monoclonal IgG2b directed against the CD2 antigen on T cells and NK cells. BTI-322 can block primary and memory alloantigen proliferative responses in vitro. BTI-322 recognizes over 90% of E-rosette-forming peripheral blood lymphocytes and T-cell leukemias. BTI-322 has immunosuppressive activity. BTI-322 effectively inhibits T cell responses in vitro to allogeneic cells. BTI-322 can be used as a T-cell deplting agent. BTI-322 can be studied in research for renal allograft rejection and steroid-refractory acute graft-versus-host disease .

Cat. No.	Product Name	Target	Research Area

HY-P5742

ELAAWCRWGFLLALLPPGIAG	EGFR	Cancer
ELAAWCRWGFLLALLPPGIAG (P5) is derived from rat HER2/neu protein with 21 amino acid length (aa 5-25). ELAAWCRWGFLLALLPPGIAG can induce cytotoxic T lymphocyte (CTL) responses in mice bearing HER2-positive tumours .

HY-P5742A

ELAAWCRWGFLLALLPPGIAG TFA	EGFR	Cancer
ELAAWCRWGFLLALLPPGIAG TFA (P5) is derived from rat HER2/neu protein with 21 amino acid length (aa 5-25). ELAAWCRWGFLLALLPPGIAG TFA can induce cytotoxic T lymphocyte (CTL) responses in mice bearing HER2-positive tumours .

HY-P3071

ShK toxin Stichodactyla helianthus neurotoxin	Potassium Channel	Inflammation/Immunology
ShK toxin blocks voltage-dependent potassium channel (K_v1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin suppresses K+ currents in cultured rat dorsal root ganglion neurons. ShK toxin also inhibits T lymphocyte proliferation .

Cat. No.	Product Name	Target	Research Area

HY-P990288

Anti-Mouse CD18 Antibody (M18/2)	Integrin Transmembrane Glycoprotein	Inflammation/Immunology
Anti-Mouse CD18 Antibody (M18/2) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse CD18. Anti-Mouse CD18 Antibody (M18/2) can neutralize lymphocyte function-associated antigen 1 (LFA-1). Anti-Mouse CD18 Antibody (M18/2) can be used for the researches of immunology, such as heart transplantation .

HY-P99120

Anti-Mouse CD11a Antibody (FD441.8)	Integrin	Inflammation/Immunology Cancer
Anti-Mouse CD11a Antibody (FD441.8) is an anti-mouse CD11a IgG2b antibody inhibitor derived from the host Rat. Anti-Mouse CD11a Antibody (FD441.8) can neutralize CD11a also known as LFA-1α (lymphocyte function-associated antigen 1 alpha). Anti-Mouse CD11a Antibody (FD441.8) can be used for the researches of inflammation, immunology and cancer, such as transplant and leukemia .

HY-P990286

Anti-Rat CD2 Antibody (OX-34)	CD2	Inflammation/Immunology Cancer
Anti-Rat CD2 Antibody (OX-34) is mouse-derived IgG2a κ type antibody inhibitor, targeting to rat CD2. Anti-Rat CD2 Antibody (OX-34) can block CD2 and inhibit the mixed lymphocyte reaction. Anti-Rat CD2 Antibody (OX-34) can be used for the researches of cancer, inflammation and immunology, such as RNK-16 tumor and arthritis .

HY-P991543

BTI-322	CD2	Inflammation/Immunology Cancer
BTI-322 is a rat monoclonal IgG2b directed against the CD2 antigen on T cells and NK cells. BTI-322 can block primary and memory alloantigen proliferative responses in vitro. BTI-322 recognizes over 90% of E-rosette-forming peripheral blood lymphocytes and T-cell leukemias. BTI-322 has immunosuppressive activity. BTI-322 effectively inhibits T cell responses in vitro to allogeneic cells. BTI-322 can be used as a T-cell deplting agent. BTI-322 can be studied in research for renal allograft rejection and steroid-refractory acute graft-versus-host disease .

Species:	Rat (11)
Tag:	His (5) Tag Free (1) Fc (5)
Source:	HEK293 (10) CHO (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P75466

	BTLA/CD272 Protein, Rat (HEK293, mFc) B- and T-lymphocyte attenuator; CD272; BTLA	Rat	HEK293
	BTLA/CD272 protein inhibits antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. It regulates immune responses through cis and trans interactions with TNFRSF14. In cis, it maintains resting state in naive T cells, while in trans, it supports survival signals in effector T cells. BTLA/CD272 interacts with PTPN6/SHP-1, PTPN11/SHP-2, and TNFRSF14/HVEM. BTLA/CD272 Protein, Rat (HEK293, mFc) is the recombinant rat-derived BTLA/CD272 protein, expressed by HEK293 , with C-mFc labeled tag.

HY-P74215

	CTLA-4 Protein, Rat (HEK293, His) Cytotoxic T-lymphocyte associated protein 4; CTLA4; CD152	Rat	HEK293
	CTLA-4 protein inhibits T-cell responses by binding strongly to CD80 and CD86 receptors, surpassing CD28. This affinity allows CTLA-4 to effectively regulate T-cell activation and immune responses. The balance between inhibitory and stimulatory signals controlled by CTLA-4 and its ligands modulates T-cell-mediated immune reactions. CTLA-4 Protein, Rat (HEK293, His) is the recombinant rat-derived CTLA-4 protein, expressed by HEK293 , with C-His labeled tag.

HY-P79326

	IL-17A Protein, Rat (CHO) 2 Publications Verification Il17a; interleukin 17A; Il17; IL-17; CTLA-8; IL-17A; interleukin-17A; Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); cytotoxic T-lymphocyte-associated antigen 8; Interleukin 17	Rat	CHO
	The IL-17A protein has important heterodimerization and homodimerization activities and is involved in a variety of processes, including responses to glucocorticoid stimulation and the regulation of cell death and transcription. IL-17A is present in the cytoplasm and extracellular space and has been implicated in diseases such as pancreatitis, inflammatory bowel disease, renal disease, and periodontal disease, and may serve as a biomarker. IL-17A Protein, Rat (CHO) is the recombinant rat-derived IL-17A protein, expressed by CHO , with tag free.

HY-P7634

	B7-1/CD80 Protein, Rat (HEK293, His) rRtB7-1, His; T-lymphocyte activation antigen CD80; Activation B7-1 antigen; CD80	Rat	HEK293
	B7-1/CD80 Protein, Rat (HEK293, His) is not only expressed on APCs, but also is expressed on T cells. B7-1:PD-L1 interaction can inhibit T cell proliferation and cytokine production.

HY-P7636

	B7-2/CD86 Protein, Rat (HEK293, His) rRtB7-2, His; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD86	Rat	HEK293
	B7-2/CD86 Protein, Rat (HEK293, His), a second CTLA4 ligand expressed on murine B cells, can serve as a costimulatory molecule for T cell activation.

HY-P76514

	NKp46/NCR1 Protein, Rat (HEK293, Fc) Activating receptor1; mAR-1; lymphocyte antigen94; Naturalkiller cell p46-related protein; NK-p46; NKp46; mNKp46	Rat	HEK293
	The NKp46/NCR1 protein is a key cytotoxic activating receptor that increases the efficiency of activated natural killer (NK) cells, particularly in targeting tumor cell lysis. Through interactions with CD3Z and FCER1G, NKp46/NCR1 orchestrates important connections that enhance the ability of NK cells to destroy tumor cells. NKp46/NCR1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived NKp46/NCR1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P74788

	LAG-3 Protein, Rat (HEK293, His) lymphocyte activation gene 3 protein; Protein FDC; CD223	Rat	HEK293
	LAG-3 (lymphocyte activation gene 3) protein is an inhibitory receptor on antigen-activated T cells, which transmits inhibitory signals by binding to ligands such as FGL1. LAG-3 is associated with CD3-TCR at the immune synapse, hinders T cell activation, and may cooperate with PDCD1/PD-1 to act as a co-receptor for PD-1. LAG-3 Protein, Rat (HEK293, His) is the recombinant rat-derived LAG-3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74216

	CTLA-4 Protein, Rat (HEK293, Fc) Cytotoxic T-lymphocyte associated protein 4; CTLA4; CD152	Rat	HEK293
	CTLA-4 protein inhibits T-cell responses by binding strongly to CD80 and CD86 receptors, surpassing CD28. This affinity allows CTLA-4 to effectively regulate T-cell activation and immune responses. The balance between inhibitory and stimulatory signals controlled by CTLA-4 and its ligands modulates T-cell-mediated immune reactions. CTLA-4 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CTLA-4 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P704555

	CTLA-4 Protein, Rat (124a.a, HEK293, Fc) Cytotoxic T-lymphocyte associated protein 4; CTLA4; CD152	Rat	HEK293
	CTLA-4 protein inhibits T-cell responses by binding strongly to CD80 and CD86 receptors, surpassing CD28. This affinity allows CTLA-4 to effectively regulate T-cell activation and immune responses. The balance between inhibitory and stimulatory signals controlled by CTLA-4 and its ligands modulates T-cell-mediated immune reactions. CTLA-4 Protein, Rat (124a.a, HEK293, Fc) is the recombinant rat-derived CTLA-4 protein, expressed by HEK293, with C-hFc labeled tag.

HY-P74398

	B7-1/CD80 Protein, Rat (HEK293, Fc) T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; B7; CD80; CD28LG; LAB7	Rat	HEK293
	B7-1/CD80, a type I membrane protein, is a member of the B7 family, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding.CD80 is also a transmembrane glycoprotein and a member of the Ig superfamily.CD80 has a crucial role in modulating T-cell immune function as a checkpoint protein at the immunological synapse.Its binding to CD28 or CTLA-4 receptors is integral to inducing T-cell proliferation and cytokine production.B7-1/CD80 Protein, Rat (HEK293, Fc) is the recombinant rat-derived B7-1/CD80 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P703697

	CLEC11A/SCGF-alpha Protein, Rat (HEK293, His) C-type lectin domain family 11 member A; lymphocyte secreted C-type lectin; Osteolectin; Stem cell growth factor; Clec11a	Rat	HEK293
	CLEC11A/SCGF-alpha Protein, Rat (HEK293, His) is the recombinant rat-derived CLEC11A/SCGF-alpha protein, expressed by HEK293, with C-His tag.

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HY-P83710M

	Rat Anti-Mouse CD86 Antibody (FITC)(YA3447) T-lymphocyte activation antigen CD86; Cd86; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1	FC	Mouse
	Rat Anti-Mouse CD86 Antibody (FITC)(YA3447) is a rat-derived and fluorescein isothiocyanate (FITC) IgG2a monoclonal antibody, targeting to CD86.

HY-P81184

	CD80 Antibody (YA3386) Activation B7-1 antigen; B lymphocyte activation antigen B7; B7; B7-1; B7-1 antigen; BB1; CD28 antigen ligand 1; CD28LG; CD28LG1; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 antigen; CD80 molecule; CD80_HUMAN; Costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; T-lymphocyte activation antigen CD80; CD80_rat.	WB, IHC-P, FC, ICC/IF	Human, Mouse
	CD80 Antibody (YA3386) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to CD80.

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