Search Result

Isoforms Recommended:	Adenosine A₁ receptor (A₁R)

Results for "

rA1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (1) Adenosine Receptor (5) Akt (1) AMPK (1) Apoptosis (3) Arrestin (1) Autophagy (1) Bacterial (4) c-Fms (1) Carbonic Anhydrase (1) COX (2) CXCR (1) Cytochrome P450 (1) Dihydroorotate Dehydrogenase (1) Drug Intermediate (1) GCGR (1) GLP Receptor (1) Interleukin Related (5) mRNA (2) p38 MAPK (1) Parasite (1) PGE synthase (1) PI3K (1) Protein Arginine Deiminase (1) RAR/RXR (1) Reactive Oxygen Species (ROS) (3) Reference Standards (2) SARS-CoV (1) Sirtuin (1) Small Interfering RNA (siRNA) (6) STAT (1) TNF Receptor (3) Transmembrane Glycoprotein (1) VEGFR (2)
By Research Areas:	Cancer (4) Cardiovascular Disease (5) Infection (7) Inflammation/Immunology (27) Metabolic Disease (4) Neurological Disease (2)
Click Chemistry:	DBCO (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (2) mRNA (2) Mouse Pre-designed siRNA Sets (2) Human Pre-designed siRNA Sets (2) siRNAs (6)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2506

Ginsenoside Ra1	Others	Cardiovascular Disease
Ginsenoside Ra1 is a component from ginseng, inhibits protein tyrosine kinase (PTK) activation induced by hypoxia/reoxygenation ^[1].

HY-103174

MRS1334	Adenosine Receptor	Cardiovascular Disease
MRS1334 is a potent and selective human adenosine A₃ receptor antagonist with K_is of 2.69 nM, >100 nM, >100 nM for hA₃, rA₁, rA_2A, respectively. MRS1334 blocks the protective effect of Cl-IB-MECA leading to significant bradycardia and elevated ST segment ^[1] . MRS1334 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-139314

A2B receptor antagonist 2	Adenosine Receptor	Metabolic Disease
A2B receptor antagonist 2 (compound 18) is an adenosine receptor A_2B antagonist, with K_i values of 2.30 μM, 6.8 μM and 3.44 μM for rA₁, rA_2A and hA_2B, respectively ^[1].

HY-P11046

IIIM1	Interleukin Related	Inflammation/Immunology
IIIM1 is an orally active anti-inflammatory peptide. IIIM1 ameliorates the symptoms of experimental autoimmune encephalomyelitis (EAE) by stimulating the proliferation of regulatory T cells and inducing them to produce RA1, and regulating the cytokine balance. IIIM1 can be used in the research of multiple sclerosis (MS) ^[1].

HY-103175

PSB36	Adenosine Receptor	Neurological Disease
PSB36 is a potent and selective antagonist of adenosine A₁ receptor, with K_is 0.12 nM, 187 nM, 552 nM, 2300 nM, and 6500 nM for *rA₁, hA_2B, rA_2A, hA₃* and rA₃ receptors respectively. PSB36 can be used for the research of hyperalgesia ^[1] .

HY-103177

PSB-10 hydrochloride	Adenosine Receptor	Inflammation/Immunology
PSB-10 hydrochloride is a potent and selective antagonist of human adenosine A3 receptor (A₃AR), with a K_i of 0.44 nM. PSB-10 hydrochloride shows more than 800-fold selectivity for hA₃ over rA₁, rA_2A, hA₁, hA_2A and hA_2B receptors (K_i=805, 6040, 1700, 2700, 30000 nM, respectively). PSB-10 hydrochloride produces thermal hyperalgesia in mice ^[1] .

HY-174619

Human IL22RA1 mRNA	mRNA	Inflammation/Immunology
Human IL22RA1 mRNA encodes the human interleukin 22 receptor subunit alpha 1 (IL22RA1) protein, a member of the class II cytokine receptor family. IL22RA1 has been shown to be a receptor for interleukin 22 (IL22).

HY-174638

Human IL13RA1 mRNA	mRNA	Inflammation/Immunology
Human IL13RA1 mRNA encodes the human interleukin 13 receptor subunit alpha 1 (IL13RA1) protein, a subunit of the interleukin 13 receptor. IL13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. It has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

HY-RS21241

Il22ra1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Il22ra1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il22ra1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Il22ra1 Mouse Pre-designed siRNA Set A Il22ra1 Mouse Pre-designed siRNA Set A

HY-RS06737

IL22RA1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL22RA1 Human Pre-designed siRNA Set A contains three designed siRNAs for IL22RA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL22RA1 Human Pre-designed siRNA Set A IL22RA1 Human Pre-designed siRNA Set A

HY-RS06688

IL13RA1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL13RA1 Human Pre-designed siRNA Set A contains three designed siRNAs for IL13RA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL13RA1 Human Pre-designed siRNA Set A IL13RA1 Human Pre-designed siRNA Set A

HY-RS19279

Il13ra1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Il13ra1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il13ra1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Il13ra1 Mouse Pre-designed siRNA Set A Il13ra1 Mouse Pre-designed siRNA Set A

HY-RS27758

Il22ra1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Il22ra1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il22ra1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Il22ra1 Rat Pre-designed siRNA Set A Il22ra1 Rat Pre-designed siRNA Set A

HY-RS25769

Il13ra1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Il13ra1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il13ra1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Il13ra1 Rat Pre-designed siRNA Set A Il13ra1 Rat Pre-designed siRNA Set A

HY-149064

Antituberculosis agent-9	Bacterial	Infection
Antituberculosis agent-9 (Compound 5a) is an orally active antitubercular agent with an MIC of 0.5 μg/mL against *H37Ra* .

HY-164416

DBCO-Dextran sulfate (MW 40000)	Drug Intermediate	Inflammation/Immunology
DBCO-Dextran sulfate (MW 40000) can be used to construct DS-EXOs in cells via click chemistry, that can be used for the research of rheumatoid arthritis (RA) .

HY-P990016

Temtokibart ARGX-112; LEO-138559; LP-0145	Interleukin Related	Inflammation/Immunology
Temtokibart is a humanized IgG1_λ2 antibody targeting *IL22RA1*. Temtokibart can be used for moderate-to-severe atopic dermatitis study ^[1].

HY-P99642

Gimsilumab MOrAb-022	c-Fms SARS-CoV	Infection Inflammation/Immunology
Gimsilumab (MORAb-022) is a human anti-GM-CSF monoclonal antibody. Gimsilumab has the potential for the research of COVID-19 and rheumatoid arthritis (RA) .

HY-P99870

Eblasakimab ASLAN004; CSL-334; MK-6105	Interleukin Related	Others
Eblasakimab (ASLAN004; CSL-334) is a human IgG4 antibody that specifically targets IL13RA1 and is primarily expressed by CHO-K1 cells ^[1].

HY-167905

ATL444	Adenosine Receptor	Neurological Disease
ATL444 is a adenosine receptor antagonist, with K_i values of 7.0, 2.5, 61.8, >1000 nM for rA₁AR, rA_2AAR, rA_2BAR, rA₃AR, respectively ^[1].

HY-N2876

Anisofolin A	Parasite Bacterial	Infection
Anisofolin A is a flavonoid that can be isolated from Anisomeles indica. Anisofolin A has antimalarial activity (IC₅₀: 4.39 μM), and antimycobacterium activity (IC₅₀: 4.50 μM) against M. tuberculosis H37Ra .

HY-125415

PF-4693627	PGE synthase	Inflammation/Immunology
PF-4693627 is a potent, selective and orally bioavailable microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor (IC₅₀=3 nM) for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA) .

HY-N11646

Ganorbiformin B	Bacterial	Infection
Ganorbiformin B is a lanostane triterpenoid. Ganorbiformin B shares the same lanostane skeleton with known ganoderic acids. The C-3 epimer of ganoderic acid T exhibits potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra .

HY-P99782

Opinercept	TNF Receptor	Inflammation/Immunology
Opinercept is a recombinant fusion protein comprising an *TNFRSF1B* fused to a human IgG1 Fc ^[1]. Opinercept is a tumor necrosis factor-alpha (TNF-alpha) inhibitor. Opinercept can be used for the research of rheumatoid arthritis (RA) .

HY-P2642

Peptide 78	CXCR	Inflammation/Immunology
Peptide 78, a chemotactic cytokine, a 78 amino acid protein member of the IL-8 or C-X-C chemokine supergene family. ENA-78 plays an important role in the elicitation of predominantly neutrophils (PMNs) into the joints of rheumatoid arthritis (RA) .

HY-P99790

Priliximab CEN 000029; cM-T412	Transmembrane Glycoprotein	Inflammation/Immunology
Priliximab (CEN 000029) is an anti-CD4 humanized monoclonal antibody. Priliximab binds to CD4 on the surface of T cells, resulting in a significant and sustained reduction in circulating CD4 ⁺ T cells. Priliximab can be used in research of rheumatoid arthritis (RA) .

HY-P99287

Elsilimomab B-E8; Anti-IL-6 MAB B-E8	Interleukin Related	Inflammation/Immunology Cancer
Elsilimomab (B-E8) is a IgG1 monoclonal antibody against interleukin-6 (IL-6), with a K_D of 22 pM and an IC₅₀ of 1.4 nM. Elsilimomab can be used for the research of multiple myeloma, renal cell carcinoma, and rheumatoid arthritis (RA) .

HY-110159

(E/Z)-Teriflunomide (E/Z)-A77 1726	Dihydroorotate Dehydrogenase	Infection Inflammation/Immunology
(E/Z)-Teriflunomide ((E/Z)-A77 1726) is the active metabolite of Leflunomide (HY-B0083). Leflunomide is an immunomodulatory agent that may exert effects by inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH). Leflunomide can be used for the research of rheumatoid arthritis (RA) .

HY-125068

RPR203494	Cytochrome P450 p38 MAPK	Inflammation/Immunology
RPR203494 is a potent inhibitor against CYP isozymes. RPR203494 shows inhibition against p38 kinase with an IC₅₀ value of 9 nM and an EC₅₀ value of 60 nM. RPR203494 demonstrates an inhibition of hepatic Cytochrome P450. RPR203494 is promising for research of rheumatoid arthritis (RA) .

HY-P99487

Briobacept BR 3FC	ADC Antibody	Inflammation/Immunology
Briobacept (BR 3FC) is a recombinant glucoprotein, consists of 2 molecules from the BLyS receptor (BR3)and a Fc domain of human IgG1. Briobacept selectively targets to BLyS (BAFF), induces B cells apoptosis. Briobacept can be used in studies of rheumatoid arthritis (RA) .

HY-P991513

BI-655064	TNF Receptor	Inflammation/Immunology
BI-655064, a humanised anti-CD40 antibody with has fragment crystallisable (Fc) regions with two mutations that prevent Fc-mediated antibody-dependent or complement-mediated cellular cytotoxicity and platelet activation. BI-655064 can be used for the study of autoimmune disease, such as lupus nephritis and rheumatoid arthritis (RA) .

HY-155031

MCI	Reactive Oxygen Species (ROS) COX	Inflammation/Immunology Cancer
MCI alleviates inflammation by macrophage reprogramming via targeting ROS scavenging and COX-2 downregulation. MCI inhibits COX-2 with an IC₅₀ value of 1.23 μM. MCI has significant anti-inflammatory effects in collagen-induced arthritis (CIA) models. MCI can be used in research for rheumatoid arthritis (RA) .

HY-151472

hCAIX/XII-IN-6	Carbonic Anhydrase	Infection
hCAIX/XII-IN-6 is an orally active carbonic anhydrase (CA) inhibitor. hCAIX/XII-IN-6 inhibits human CA isoforms hCA I, II, IV, IX, and XII with K_i values of 6697 nM, 2950 nM, 4093 nM, 4.1 nM and 7.7 nM, respectively. hCAIX/XII-IN-6 can be used for the research of rheumatoid arthritis (RA) .

HY-173321

PAD4-IN-5	Protein Arginine Deiminase	Inflammation/Immunology
PAD4-IN-5 (Example 18) is a PAD4 inhibitor with IC₅₀s of ≤10 nM and 101-500 nM for human PAD4 (hPAD4) under 50 µM Ca ²⁺ and 1 mM Ca ²⁺ conditions, respectively. PAD4-IN-5 can be used for the study of autoimmune disease, such as rheumatoid arthritis (RA) .

HY-118530

Bucillamine 2 Publications Verification SA96; Thiobutarit	VEGFR	Cardiovascular Disease Inflammation/Immunology
Bucillamine (SA96) is an orally active and potent sulfhydryl donor and antioxidant. Bucillamine is also an antirheumatic agent with antiangiogenic properties. Bucillamine can protect against Ischemia/reperfusion (I/R) injury in high-risk organ transplants. Bucillamine inhibits the production of VEGF. Bucillamine can be used for the research of choroidal neovascularization (CNV) and rheumatoid arthritis (RA) .

HY-P3491

Pegloxenatide Polyethylene glycol loxenatide; PEX 168	GCGR PI3K Akt Reactive Oxygen Species (ROS) Autophagy Interleukin Related Sirtuin AMPK Apoptosis	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Pegloxenatide (Polyethylene glycol loxenatide) is a long-acting glucagon-like peptide-1 receptor (GLP-1RA) agonist. Pegloxenatide has various activities such as lowering blood glucose, lowering blood lipids, improving body weight, anti-inflammation, promoting wound healing, protecting the liver, and protecting the heart. Pegloxenatide can be used in the research of type 2 diabetes and its multiple complications ^[1] .

HY-118530R

Bucillamine (Standard) SA96 (Standard); Thiobutarit (Standard)	Reference Standards VEGFR	Cardiovascular Disease Inflammation/Immunology
Bucillamine (Standard) is the analytical standard of Bucillamine. This product is intended for research and analytical applications. Bucillamine (SA96) is an orally active and potent sulfhydryl donor and antioxidant. Bucillamine is also an antirheumatic agent with antiangiogenic properties. Bucillamine can protect against Ischemia/reperfusion (I/R) injury in high-risk organ transplants. Bucillamine inhibits the production of VEGF. Bucillamine can be used for the research of choroidal neovascularization (CNV) and rheumatoid arthritis (RA) .

HY-N1976

(+)-(3R,8S)-Falcarindiol 1 Publications Verification (3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol	Bacterial	Infection Inflammation/Immunology Cancer
(+)-(3R,8S)-Falcarindiol is a polyacetylene found in carrots, has antimycobacterial activity, with an IC₅₀ of 6 μM and MIC of 24 μM against Mycobacterium tuberculosis H37Ra . Antineoplastic and anti-inflammatory activity . (+)-(3R,8S)-Falcarindiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-118761

5,6-Epoxyretinoic acid 5,6-epoxy atrA; 5,6-epoxy rA	RAR/RXR	Metabolic Disease
all-trans-5,6-epoxy Retinoic acid (5,6-epoxy RA) is an agonist of all isoforms of the retinoic acid receptor (RAR; EC₅₀s=77, 35, and 4 nM for RARα, RARβ, and RARγ, respectively). 5,6-epoxy RA (1 μM) also induces growth arrest of MCF-7 and NB4 cells in vitro. It is a natural metabolite of all-trans retinoic acid, which is a metabolite of vitamin A.

HY-175701

CT-996 RO7795081; RG6652	GLP Receptor Arrestin	Metabolic Disease
CT-996 is an orally active *GLP-1RA* agonist, with an EC₅₀ of 0.49 nM. CT-996 reduces the β-arrestin recruitment and *GLP-1R* internalization. CT-996 suppresses postprandial blood glucose following a mixed meal tolerance test (MMTT) in mice expressing the human GLP-1 receptor and enhances glucose stimulated insulin secretion (GSIS) during an intravenous glucose challenge in obese monkeys. CT-996 can be used for the study of type 2 diabetes (T2D) and obesity ^[1] .

HY-P99459

Baminercept 2 Publications Verification BG 9924; TT-47	TNF Receptor	Inflammation/Immunology
Baminercept (BG 9924) is an anti-lymphotoxin β receptor (LTβR) IgG fusion protein (LTβR-Ig). Baminercept selectively binds to the LTβR ligand LTα/β heterotrimer and LIGHT, block the LTβR signaling pathway, and inhibits the expression of chemokines such as CXCL13. Baminercept also regulates peripheral blood B cell and T cell subsets, reduces the transcription of IFN-induced genes. Thereby, Baminercept inhibits the formation of high endothelial venules and reticular structures in lymphoid tissues, and affects immune cell migration. Baminercept can be used for the study of autoimmune diseases such as primary Sjogren's syndrome (pSS) and rheumatoid arthritis (RA) .

HY-N2435R

[8]-Shogaol (Standard)	Reference Standards COX Apoptosis	Cancer
-Shogaol (Standard) is the analytical standard of -Shogaol. This product is intended for research and analytical applications. -Shogaol, a kind of stimulating compound in ginger, has antiplatelet (IC₅₀=5 μM), anti-cancer and anti-inflammatory activity. -Shogaol inhibited COX-2 (IC₅₀=17.5 μM), which led to the decline of human leukemia cells. 8-Shogaol Selective direction TAK1 sum TAK1-TAB1 (IC₅₀=5 μM), suppress IKK, Akt sum MAPK signal pathway, and reverse synovitis synovial sum Air dampness (RA) .

HY-N16465

Cinnamtannin D1	Apoptosis Reactive Oxygen Species (ROS) STAT	Inflammation/Immunology
Cinnamtannin D1 is an orally active polyphenolic compound with immunosuppressive activity. Cinnamtannin D1 regulates the balance of Th17/Treg cells by inhibiting AHR expression. Cinnamtannin D1 reduces apoptosis and ROS in INS-1 cells and primary cultured murine islets induced by Palmitic acid (PA) (HY-N0830). Cinnamtannin D1 reduces Th17 cell differentiation via downregulating p-STAT3/RORγt and promotes Treg cell differentiation via upregulating p-STAT5/Foxp3. Cinnamtannin D1 exerts excellent anti-arthritic efficacy in collagen-induced arthritis (CIA) model of mice. Cinnamtannin D1 can be used for the study of rheumatoid arthritis (RA) .

Cat. No.	Product Name	Target	Research Area

HY-P2171A

CCP peptide TFA 1 Publications Verification	Peptides	Inflammation/Immunology
CCP peptide TFA is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide TFA functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA) .

HY-P10086

TREM-1 inhibitory peptide GF9 1 Publications Verification Human TREM-1(213-221)	Peptides	Inflammation/Immunology
TREM-1 inhibitory peptide GF9 (Human TREM-1(213-221)) is a ligand‐independent TREM‐1 inhibitory nonapeptide GF9 that can blunt excessive inflammation caused by rheumatoid arthritis (RA) .

HY-P2642

Peptide 78	CXCR	Inflammation/Immunology
Peptide 78, a chemotactic cytokine, a 78 amino acid protein member of the IL-8 or C-X-C chemokine supergene family. ENA-78 plays an important role in the elicitation of predominantly neutrophils (PMNs) into the joints of rheumatoid arthritis (RA) .

HY-P3491

Pegloxenatide Polyethylene glycol loxenatide; PEX 168	GCGR PI3K Akt Reactive Oxygen Species (ROS) Autophagy Interleukin Related Sirtuin AMPK Apoptosis	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Pegloxenatide (Polyethylene glycol loxenatide) is a long-acting glucagon-like peptide-1 receptor (GLP-1RA) agonist. Pegloxenatide has various activities such as lowering blood glucose, lowering blood lipids, improving body weight, anti-inflammation, promoting wound healing, protecting the liver, and protecting the heart. Pegloxenatide can be used in the research of type 2 diabetes and its multiple complications ^[1] .

HY-P11046

IIIM1	Interleukin Related	Inflammation/Immunology
IIIM1 is an orally active anti-inflammatory peptide. IIIM1 ameliorates the symptoms of experimental autoimmune encephalomyelitis (EAE) by stimulating the proliferation of regulatory T cells and inducing them to produce RA1, and regulating the cytokine balance. IIIM1 can be used in the research of multiple sclerosis (MS) ^[1].

HY-P2171

CCP peptide	Peptides	Inflammation/Immunology
CCP peptide is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA) .

Cat. No.	Product Name	Target	Research Area

HY-P990016

Temtokibart ARGX-112; LEO-138559; LP-0145	Interleukin Related	Inflammation/Immunology
Temtokibart is a humanized IgG1_λ2 antibody targeting *IL22RA1*. Temtokibart can be used for moderate-to-severe atopic dermatitis study ^[1].

HY-P99642

Gimsilumab MOrAb-022	c-Fms SARS-CoV	Infection Inflammation/Immunology
Gimsilumab (MORAb-022) is a human anti-GM-CSF monoclonal antibody. Gimsilumab has the potential for the research of COVID-19 and rheumatoid arthritis (RA) .

HY-P99870

Eblasakimab ASLAN004; CSL-334; MK-6105	Interleukin Related	Others
Eblasakimab (ASLAN004; CSL-334) is a human IgG4 antibody that specifically targets IL13RA1 and is primarily expressed by CHO-K1 cells ^[1].

HY-P99287

Elsilimomab B-E8; Anti-IL-6 MAB B-E8	Interleukin Related	Inflammation/Immunology Cancer
Elsilimomab (B-E8) is a IgG1 monoclonal antibody against interleukin-6 (IL-6), with a K_D of 22 pM and an IC₅₀ of 1.4 nM. Elsilimomab can be used for the research of multiple myeloma, renal cell carcinoma, and rheumatoid arthritis (RA) .

HY-P99487

Briobacept BR 3FC	ADC Antibody	Inflammation/Immunology
Briobacept (BR 3FC) is a recombinant glucoprotein, consists of 2 molecules from the BLyS receptor (BR3)and a Fc domain of human IgG1. Briobacept selectively targets to BLyS (BAFF), induces B cells apoptosis. Briobacept can be used in studies of rheumatoid arthritis (RA) .

HY-P99459

Baminercept 2 Publications Verification BG 9924; TT-47	TNF Receptor	Inflammation/Immunology
Baminercept (BG 9924) is an anti-lymphotoxin β receptor (LTβR) IgG fusion protein (LTβR-Ig). Baminercept selectively binds to the LTβR ligand LTα/β heterotrimer and LIGHT, block the LTβR signaling pathway, and inhibits the expression of chemokines such as CXCL13. Baminercept also regulates peripheral blood B cell and T cell subsets, reduces the transcription of IFN-induced genes. Thereby, Baminercept inhibits the formation of high endothelial venules and reticular structures in lymphoid tissues, and affects immune cell migration. Baminercept can be used for the study of autoimmune diseases such as primary Sjogren's syndrome (pSS) and rheumatoid arthritis (RA) .

HY-P99782

Opinercept	TNF Receptor	Inflammation/Immunology
Opinercept is a recombinant fusion protein comprising an *TNFRSF1B* fused to a human IgG1 Fc ^[1]. Opinercept is a tumor necrosis factor-alpha (TNF-alpha) inhibitor. Opinercept can be used for the research of rheumatoid arthritis (RA) .

HY-P99790

Priliximab CEN 000029; cM-T412	Transmembrane Glycoprotein	Inflammation/Immunology
Priliximab (CEN 000029) is an anti-CD4 humanized monoclonal antibody. Priliximab binds to CD4 on the surface of T cells, resulting in a significant and sustained reduction in circulating CD4 ⁺ T cells. Priliximab can be used in research of rheumatoid arthritis (RA) .

HY-P991513

BI-655064	TNF Receptor	Inflammation/Immunology
BI-655064, a humanised anti-CD40 antibody with has fragment crystallisable (Fc) regions with two mutations that prevent Fc-mediated antibody-dependent or complement-mediated cellular cytotoxicity and platelet activation. BI-655064 can be used for the study of autoimmune disease, such as lupus nephritis and rheumatoid arthritis (RA) .

Species:	Human (5) Mouse (4) Rat (1) Cynomolgus (2) Canine (4)
Tag:	His (9) Avi (3) Fc (7)
Source:	HEK293 (16)

Cat. No.	Compare	Product Name	Species	Source

HY-P70196

	IL-13R alpha 1 Protein, Mouse (HEK293, Fc) rMuInterleukin-13 receptor subunit alpha-1/IL-13rA1, Fc; Interleukin-13 receptor subunit alpha-1; IL-13rA1; Interleukin-13-binding protein; Novel cytokine receptor 4; NR4; CD213a1	Mouse	HEK293
	The IL-13R α 1 protein binds to IL13 with low affinity and, when combined with IL4RA, forms a functional IL13 receptor. It also functions together with IL4RA as an alternative accessory protein for IL4 signaling. IL-13R alpha 1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76990

	IL-13R alpha 2 Protein, Canine (HEK293, His) Interleukin-13 receptor subunit alpha-1; IL-13rA1; NR4; CD213a1	Canine	HEK293
	The IL-13R α2 protein is a receptor for interleukin 13 (IL-13), a signaling molecule involved in immune responses. By binding to IL-13, the IL-13R α2 protein is thought to regulate IL-13-mediated immune responses and may serve as a therapeutic target for diseases associated with IL-13 dysregulation. IL-13R alpha 2 Protein, Canine (HEK293, His) is the recombinant canine-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P78699

	IL-13R alpha 1 Protein, Mouse (HEK293, His) IL13rA1; CD213A1; IL-13rA; NR4; RP13-128O4.2; IL13Rα1	Mouse	HEK293
	The IL-13R alpha 1 protein forms a receptor for interleukin-13 when it complexes with IL4RA, activating pathways in allergy response and bronchial asthma. It exhibits ubiquitous expression, including in large intestine adult, colon adult, and 27 other tissues. IL-13R alpha 1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P77424

	IL-22R alpha 1 Protein, Canine (HEK293, His) Interleukin-22 receptor subunit alpha-1; IL-22R-alpha-1; IL-22rA1; CRF2-9; ZcytoR11; IL22R	Canine	HEK293
	IL-22R alpha 1 (IL22RA1) Protein is an IL-22 receptor. IL-22R alpha 1 Protein interacts with IL-22 to activate the JAK/STAT cascade thereby inhibits IL-22 mediated promotion of cell proliferation and anti-apoptosis. IL-22R alpha 1 Protein, Canine (HEK293, His) is expressed by HEK 293 cells and has a transmembrane region (M1-The226) with a His tag at the C-terminus.

HY-P72594

	IL-13R alpha 1 Protein, Human (HEK293, His) Interleukin-13 receptor subunit alpha-1; IL-13R-alpha-1; IL-13rA1; CT19; CD213a1; IL13R	Human	HEK293
	The IL13RA1 protein is critical in immune signaling and binds with low affinity to IL13. It binds to IL4RA to form a functional IL13 receptor for cellular responses. IL-13R alpha 1 Protein, Human (HEK293, His) is the recombinant human-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76417

	IL-13R alpha 1 Protein, Rat (HEK293, Fc) Interleukin-13 receptor subunit alpha-1; IL-13R-alpha-1; IL-13rA1; CT19; CD213a1; IL13R	Rat	HEK293
	Interleukin 13 receptor subunit alpha 1 is a subunit of the interleukin 13 receptor. Interleukin 13 receptor subunit alpha 1 has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. IL-13R alpha 1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77403

	IL-13R alpha 1 Protein, Cynomolgus (HEK293, His) Interleukin-13 receptor subunit alpha-1; IL-13R-alpha-1; IL-13rA1; CT19; CD213a1; IL13R	Cynomolgus	HEK293
	The IL-13R α 1 protein binds to IL13 with low affinity and, when combined with IL4RA, forms a functional IL13 receptor. It also functions together with IL4RA as an alternative accessory protein for IL4 signaling. IL-13R alpha 1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P77967

	IL-22R alpha 1 Protein, Human (HEK293, Fc) IL-22R-alpha-1; IL-22rA1; CRF2-9; IL22R; IL22R1; IL-TIF-R1; zcytoR11	Human	HEK293
	IL-22R alpha 1 (IL22RA1) Protein is an IL-22 receptor. IL-22R alpha 1 Protein interacts with IL-22 to activate the JAK/STAT cascade thereby inhibits IL-22 mediated promotion of cell proliferation and anti-apoptosis. IL-22R alpha 1 Protein, Human (HEK293, Fc) is expressed by HEK 293 cells and has a transmembrane region (H16-T228) with a Fc tag at the C-terminus.

HY-P76989

	IL-13R alpha 2 Protein, Canine (HEK293, Fc) Interleukin-13 receptor subunit alpha-1; IL-13rA1; NR4; CD213a1	Canine	HEK293
	The IL-13R α2 protein is a receptor for interleukin 13 (IL-13), a signaling molecule involved in immune responses. By binding to IL-13, the IL-13R α2 protein is thought to regulate IL-13-mediated immune responses and may serve as a therapeutic target for diseases associated with IL-13 dysregulation. IL-13R alpha 2 Protein, Canine (HEK293, Fc) is the recombinant canine-derived IL-13R alpha 2 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77423

	IL-22R alpha 1 Protein, Canine (HEK293, Fc) Interleukin-22 receptor subunit alpha-1; IL-22R-alpha-1; IL-22rA1; CRF2-9; ZcytoR11; IL22R	Canine	HEK293
	IL-22R alpha 1 (IL22RA1) Protein is an IL-22 receptor. IL-22R alpha 1 Protein interacts with IL-22 to activate the JAK/STAT cascade thereby inhibits IL-22 mediated promotion of cell proliferation and anti-apoptosis. IL-22R alpha 1 Protein, Canine (HEK293, Fc) is expressed by HEK 293 cells and with a Fc tag at the C-terminus.

HY-P77969

	IL-22R alpha 1 Protein, Mouse (HEK293, Fc) 1 Publications Verification IL-22R-alpha-1; IL-22rA1; CRF2-9; IL22R; IL22R1; IL-TIF-R1; zcytoR11	Mouse	HEK293
	IL-22R α 1 and IL-10R β together form IL20, IL22 and IL24 receptor complexes, activating different signaling pathways. Within the IL22 receptor, IL-22R α 1 binds to IL10RB and mediates IL22 signaling through the JAK/STAT and MAPK1/MAPK3/Akt pathways. IL-22R alpha 1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IL-22R alpha 1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P700744

	IL-22R alpha 1 Protein, Cynomolgus (HEK293, His) IL-22R-alpha-1; IL-22rA1; CRF2-9; IL22R; IL22R1; IL-TIF-R1; zcytoR11	Cynomolgus	HEK293
	IL-22R α 1 and IL-10R β together form IL20, IL22 and IL24 receptor complexes, activating different signaling pathways. Within the IL22 receptor, IL-22R α 1 binds to IL10RB and mediates IL22 signaling through the JAK/STAT and MAPK1/MAPK3/Akt pathways. IL-22R alpha 1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-22R alpha 1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P703975

	IL-22R alpha 1 Protein, Human (HEK293, His) IL-22R-alpha-1; IL-22rA1; CRF2-9; IL22R; IL22R1; IL-TIF-R1; zcytoR11	Human	HEK293
	Interleukin 10 receptor beta (IL-10Rβ) is an important component of the interleukin 10 (IL-10), IL-22 and IL-24 receptor complex and plays a central role in mediating multiple signaling pathways effect. As part of the IL-10 receptor, IL-10Rβ forms a functional heterodimer with IL-10Rα and initiates IL-10 signaling through the JAK/STAT pathway. IL-22R alpha 1 Protein, Human (HEK293, His) is the recombinant human-derived IL-22R alpha 1 protein, expressed by HEK293, with C-His labeled tag.

HY-P72381

	IL-13R alpha 1 Protein, Mouse (Biotinylated, HEK293, Avi-His) Interleukin-13 receptor subunit alpha-1; IL-13rA1; Interleukin-13-binding protein; Novel cytokine receptor 4; NR4; CD213a1	Mouse	HEK293
	The IL-13R α 1 protein binds to IL13 with low affinity and, when combined with IL4RA, forms a functional IL13 receptor. It also functions together with IL4RA as an alternative accessory protein for IL4 signaling. IL-13R alpha 1 Protein, Mouse (Biotinylated, HEK293, Avi-His) is the recombinant mouse-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag.

HY-P78163

	IL-13R alpha 1 Protein, Human (Biotinylated, HEK293, His-Avi) IL-13 R alpha 1; IL13R; IL13rA; CT19; IL13rA1; NR4; CD213A1; AI882074	Human	HEK293
	The IL13RA1 protein is critical in immune signaling and binds with low affinity to IL13. It binds to IL4RA to form a functional IL13 receptor for cellular responses. IL-13R alpha 1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-His, C-Avi labeled tag.

HY-P705123

	IL-13R alpha 1 Protein, Human (Biotinylated, HEK293, Fc-Avi) IL-13 R alpha 1; IL13R; IL13rA; CT19; IL13rA1; NR4; CD213A1; AI882074	Human	HEK293

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HY-P81879

	IL-13 Receptor alpha 1 Antibody (YA1624) IL13rA1; IL13R; IL13rA; Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13rA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1	WB	Human
	IL-13 Receptor alpha 1 Antibody (YA1624) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-13 Receptor alpha 1.

HY-P84441

	IL-13 Receptor alpha 1 Antibody (YA4138) IL13rA1; NR4; CT19; IL-13rA	WB, FC, ELISA	Human
	IL-13 Receptor alpha 1 Antibody (YA4138) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL-13 Receptor alpha 1.

HY-P81632

	IL-13 Receptor alpha 1 Antibody (YA1377) IL13rA1; IL13R; IL13rA; Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13rA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1	FC, ELISA	Human
	IL-13 Receptor alpha 1 Antibody (YA1377) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-13 Receptor alpha 1.