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Results for "

parathyroid

" in MedChemExpress (MCE) Product Catalog:

69

Inhibitors & Agonists

35

Peptides

5

Natural
Products

5

Recombinant Proteins

2

Isotope-Labeled Compounds

8

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2279A
    Parathyroid hormone (1-34) (rat) acetate
    1 Publications Verification

    Thyroid Hormone Receptor Metabolic Disease Endocrinology
    Parathyroid hormone (1-34) (rat) (acetate) is a parathyroid hormone. Parathyroid hormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroid hormone (1-34) (rat) can be used for the research of osteoporosis .
    Parathyroid hormone (1-34) (rat) acetate
  • HY-P2279
    Parathyroid hormone (1-34) (rat)
    1 Publications Verification

    Thyroid Hormone Receptor Metabolic Disease Endocrinology
    Parathyroid hormone (1-34) (rat) is a parathyroid hormone. Parathyroid hormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroid hormone (1-34) (rat) can be used for the research of osteoporosis .
    Parathyroid hormone (1-34) (rat)
  • HY-P1252
    Parathyroid Hormone (1-34), bovine
    2 Publications Verification

    Thyroid Hormone Receptor Metabolic Disease
    Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .
    Parathyroid Hormone (1-34), bovine
  • HY-P2510

    Thyroid Hormone Receptor Metabolic Disease
    Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns .
    Parathyroid Hormone (1-34), human, biotinylated
  • HY-P0059
    Teriparatide
    5+ Cited Publications

    Human parathyroid hormone-(1-34); hPTH (1-34)

    PTHR Thyroid Hormone Receptor Others Cancer
    Teriparatide (Human parathyroid hormone-(1-34)) is a PTH1 receptor agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research .
    Teriparatide
  • HY-P10078

    Thyroid Hormone Receptor Inflammation/Immunology
    pTH (39-84) (human) is a parathyroid hormone (PTH) C-terminal fragment. pTH (39-84) (human) stimulates osteoclast formation .
    pTH (39-84) (human)
  • HY-P1252A

    Thyroid Hormone Receptor Metabolic Disease
    Parathyroid Hormone (1-34), bovine TFA is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .
    Parathyroid Hormone (1-34), bovine TFA
  • HY-P0059A

    Human parathyroid hormone-(1-34) acetate hydrate; hPTH (1-34) acetate hydrate

    PTHR Thyroid Hormone Receptor Others Cancer
    Teriparatide acetate hydrate (Human parathyroid hormone-(1-34) acetate hydrate) is a PTH1 receptor agonist. Teriparatide acetate hydrate (Human parathyroid hormone-(1-34) acetate hydrate) can be used for osteoporosis research .
    Teriparatide acetate hydrate
  • HY-P4857

    Thyroid Hormone Receptor Endocrinology
    pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent antagonist of parathyroid hormone (PTH) .
    pTH-Related Protein (7-34) amide (human, mouse, rat)
  • HY-14752

    SB 751689

    CaSR Metabolic Disease Endocrinology
    Ronacaleret (SB 751689) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret (SB 751689) is used for the study of postmenopausal osteoporosis .
    Ronacaleret
  • HY-15104

    SB 751689A

    CaSR Metabolic Disease Endocrinology
    Ronacaleret hydrochloride (SB 751689A) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret hydrochloride (SB 751689A) is used for the study of postmenopausal osteoporosis .
    Ronacaleret hydrochloride
  • HY-106608

    Litoralon

    Thyroid Hormone Receptor Neurological Disease
    Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine can be used for the research of antiepileptic and anti-amnesia .
    Glutaurine
  • HY-106608A

    Litoralon TFA

    Thyroid Hormone Receptor Neurological Disease
    Glutaurine (Litoralon) TFA containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine (Litoralon) TFA, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine (Litoralon) TFA can be used for the research of antiepileptic and anti-amnesia .
    Glutaurine TFA
  • HY-17613
    Evocalcet
    3 Publications Verification

    KHK7580

    CaSR Metabolic Disease
    Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .
    Evocalcet
  • HY-14401

    CLTX-305; JTT-305; MK-5442

    CaSR Thyroid Hormone Receptor Endocrinology
    Encaleret (CLTX-305) is an orally active antagonist of the calcium-sensing receptor (CaSR), with an IC50 of 0.012 μM. Encaleret can promote the secretion of parathyroid hormone. Encaleret can be used in the research of diseases such as osteoporosis and autosomal dominant hypocalcemia type 1 .
    Encaleret
  • HY-10003A

    Thyroid Hormone Receptor Metabolic Disease
    1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion .
    1α-Hydroxy-3-epi-vitamin D3
  • HY-17613R

    KHK7580 (Standard)

    Reference Standards CaSR Metabolic Disease
    Evocalcet (Standard) is the analytical standard of Evocalcet. This product is intended for research and analytical applications. Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .
    Evocalcet (Standard)
  • HY-P10909

    MBX 2109

    Thyroid Hormone Receptor Endocrinology
    Canvuparatide (MBX 2109) is a prodrug for parathyroid hormone (PTH) peptide that releases the bioactive PTH[1-32] peptide agonist that retains a fatty acylated lysine (Lys33) at the C-terminus, thereby extending the halflife of Canvuparatide. Canvuparatide can be used for the symptoms of hypoparathyroidism such as hypocalcemia and hyperphosphatemia .
    Canvuparatide
  • HY-P1418

    Thyroid Hormone Receptor Endocrinology
    DPC-AJ1951, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 in ex vivo and in vivo assays of bone resorption .
    DPC-AJ1951
  • HY-P1418A

    Thyroid Hormone Receptor Endocrinology
    DPC-AJ1951 TFA, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 TFA in ex vivo and in vivo assays of bone resorption .
    DPC-AJ1951 TFA
  • HY-P4697A

    Thyroid Hormone Receptor Endocrinology
    pTH (44-68) (human) TFA is a fragment of human parathyroid hormone (pTH) that lacks the adenylate cyclase-stimulating activity of intact pTH. pTH (44-68) (human) TFA can be used to study the mechanism of action of pTH .
    pTH (44-68) (human) TFA
  • HY-A0245

    VD/VDR Metabolic Disease
    Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) .
    Dihydrotachysterol
  • HY-148350

    PTHR Cancer
    DS69910557 is a potent, selective and orally activehuman parathyroid hormone receptor 1 (hPTHR1) antagonist. DS69910557 has antagonistic activity for PTHR1 with an IC50 value of 0.08 μM. DS69910557 can be used for the research of hyperparathyroidism, hypercalcemia of malignancy and osteoporosis .
    DS69910557
  • HY-B2097

    YM 175; Bisphonal

    Farnesyl Transferase Metabolic Disease
    Incadronate disodium (YM 175) is a bisphosphonate with strong inhibitory activity on bone resorption. Incadronate disodium indirectly stimulates renal 25-hydroxyvitamin D-1-hydroxylase by increasing circulating parathyroid hormone. Incadronate disodium, a cholesterol-lowering agent, is a potent inhibitor of rat liver microsomal squalene synthase (Ki=57 nM). Incadronate disodium inhibits sterol biosynthesis in mouse macrophage J774 cells (IC50=64 μM). Incadronate disodium has the potential for malignant tumors research .
    Incadronate disodium
  • HY-109106B

    (Rac)-SK-1403 free acid; (Rac)-AJT240 free acid; (Rac)-PLS240 free acid

    CaSR Endocrinology
    (Rac)-Upacicalcet is the racemate of Upacicalcet (HY-109106). Upacicalcet is a non-peptide calcimimetic that acts as a CaSR agonist (EC50 = 10.8 nM). Upacicalcet reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet is useful for studying SHPT .
    (Rac)-Upacicalcet
  • HY-P4690

    Thyroid Hormone Receptor Endocrinology
    pTH (13-34) (human) is apTH ((Human parathyroid hormone) fragment.
    pTH (13-34) (human)
  • HY-P4696

    Thyroid Hormone Receptor Endocrinology
    pTH (3-34) (bovine) is apTH ((Human parathyroid hormone) fragment.
    pTH (3-34) (bovine)
  • HY-P4692

    Thyroid Hormone Receptor Endocrinology
    pTH (1-44) (human) is apTH ((Human parathyroid hormone) fragment.
    pTH (1-44) (human)
  • HY-P4697

    Thyroid Hormone Receptor Endocrinology
    pTH (44-68) (human) is apTH ((Human parathyroid hormone) fragment.
    pTH (44-68) (human)
  • HY-P4700

    Thyroid Hormone Receptor Endocrinology
    pTH (53-84) (human) is apTH ((Human parathyroid hormone) fragment.
    pTH (53-84) (human)
  • HY-109106A

    SK-1403; AJT240; PLS240

    CaSR Endocrinology
    Upacicalcet sodium is a non-peptide calcimimetic that acts as a CaSR agonist (EC50 = 10.8 nM). Upacicalcet sodium reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet sodium sodium improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet sodium sodium inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet sodium is useful for studying SHPT .
    Upacicalcet sodium
  • HY-109106

    SK-1403 free acid; AJT240 free acid; PLS240 free acid

    CaSR Endocrinology
    Upacicalcet is a non-peptide calcimimetic that acts as a CaSR agonist (EC50 = 10.8 nM). Upacicalcet reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet is useful for studying SHPT .
    Upacicalcet
  • HY-17613S

    KHK7580-d4

    Isotope-Labeled Compounds CaSR Metabolic Disease
    Evocalcet-d4 (KHK7580-d4) is deuterium labeled Evocalcet. Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .
    Evocalcet-d4
  • HY-P1852

    Adenylate Cyclase Neurological Disease
    TIP 39, Tuberoinfundibular Neuropeptide is a neuropeptide and parathyroid hormone 2 receptor (PTH2R) agonist. TIP 39 is highly conserved among species. TIP39 from all species activates adenylyl cyclase and elevates intracellular calcium levels through parathyroid hormone 2 receptor (PTH2R) .
    TIP 39, Tuberoinfundibular Neuropeptide
  • HY-100856

    PTHR Endocrinology
    PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor.
    PCO371
  • HY-P4715

    PTHR Endocrinology
    (Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat) is a peptide and can be used as a parathyroid hormone (PTH) receptor ligand .
    (Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat)
  • HY-50919
    Paricalcitol
    Maximum Cited Publications
    14 Publications Verification

    VD/VDR Metabolic Disease Cancer
    Paricalcitol, a vitamin D analogue, is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure.
    Paricalcitol
  • HY-76937

    VD/VDR Endocrinology
    Impurity of Doxercalciferol is an impurity of doxercalciferol, which is a synthetic analog of ergocalciferol (vitamin D2), used as a agent for secondary hyperparathyroidism and metabolic bone disease, and it suppresses parathyroid synthesis and secretion.
    Impurity of Doxercalciferol
  • HY-P4800

    Human PTHrP(107-139)

    Thyroid Hormone Receptor Metabolic Disease Inflammation/Immunology
    Osteostatin (human), a fragment of parathyroid hormone-related protein (PTHrP) 107-139, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis .
    Osteostatin (human)
  • HY-76585

    VD/VDR Metabolic Disease
    Paricalcitol-d6 is the deuterium labeled Paricalcitol. Paricalcitol is a agent used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure .
    Paricalcitol-d6
  • HY-P4849

    PTHR Others
    pTH-Related Protein (1-37) (human, mouse, rat), the peptide analogue of pTH-Related Protein (pTHrP). pTHrP refers to parathyroid-hormone-related protein, involved in physiological regulation of bone formation .
    pTH-Related Protein (1-37) (human, mouse, rat)
  • HY-16498

    PCK-3145

    Apoptosis Cancer
    Tigapotide (PCK-3145) is an anti-tumour peptide that reduces the development of skeletal metastases associated with prostate cancer. Tigapotide induces apoptosis and reduces tumour parathyroid hormone-related peptide (PTHrP) levels .
    Tigapotide
  • HY-P3075

    pTHrP (1-34)

    Thyroid Hormone Receptor Inflammation/Immunology
    pTH-Related Protein (1-34) (human, mouse, rat), a fragment of parathyroid hormone-related protein, is an anabolic agent. pTH-Related Protein (1-34) (human, mouse, rat) can be used for postmenopausal osteoporosis study .
    pTH-Related Protein (1-34) (human,mouse,rat)
  • HY-P4798

    Human PTHrP(107-111) amide

    PTHR Others
    Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) (Human PTHrP (107-111) amide) is a C-terminal parathyroid hormone-related protein fragment that can inhibit bone resorption .
    Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat)
  • HY-50919R

    Reference Standards VD/VDR Metabolic Disease Cancer
    Paricalcitol (Standard) is the analytical standard of Paricalcitol. This product is intended for research and analytical applications. Paricalcitol, a vitamin D analogue, is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure.
    Paricalcitol (Standard)
  • HY-P4856

    PTHR PKC Endocrinology
    pTH-Related Protein (1-40) (human, mouse, rat) stimulates calcium uptake in rat intestinal cells through PTHR1 receptor and PKCα/β signaling pathways. pTH-Related Protein (1-40) up-regulates parathyroid hormone 1 receptor (PTHR1) protein, four transcellular calcium transporters, potential vanillin member 6 (TRPV6), calcium-binding protein-D9K (CaBP-D9k), sodium-calcium Exchanger 1 (NCX1) and plasma membrane calcium ATPase 1 (PMCA1) .
    pTH-Related Protein (1-40) (human, mouse, rat)
  • HY-P10309

    [Nle8'18,Tyr34]hPTH (3-34) amide

    PTHR Endocrinology
    [Nle8,18,Tyr34]-pTH (3-34) amide human ([Nle8,18,Tyr34]hPTH (3-34) amide) is a parathyroid hormone (PTH) analog .
    [Nle8,18,Tyr34]-pTH (3-34) amide (human)
  • HY-112171R

    γ-Glu-Ala (Standard)

    Endogenous Metabolite CaSR Others
    γ-L-Glutamyl-L-alanine (Standard) is the analytical standard of γ-L-Glutamyl-L-alanine. This product is intended for research and analytical applications. γ-L-Glutamyl-L-alanine, composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins. γ-L-Glutamyl-L-alanine is a natural substrate of the γ-Glutamylcyclotransferase. γ-L-Glutamyl-L-alanine is a positive modulator of calcium-sensing receptor (CaR) function .
    γ-L-Glutamyl-L-alanine (Standard)
  • HY-112171
    γ-L-Glutamyl-L-alanine
    1 Publications Verification

    γ-Glu-Ala

    Endogenous Metabolite CaSR Others
    γ-L-Glutamyl-L-alanine (γ-Glu-Ala), composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins. γ-L-Glutamyl-L-alanine is a natural substrate of the γ-Glutamylcyclotransferase. γ-L-Glutamyl-L-alanine is a positive modulator of calcium-sensing receptor (CaR) function .
    γ-L-Glutamyl-L-alanine
  • HY-N2098
    Obtusifolin
    1 Publications Verification

    NF-κB Cancer
    Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway . Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein .
    Obtusifolin

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