Search Result

Results for "

pPLCγ1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Payload (1) AMPK (15) Antibiotic (2) Apoptosis (2) Autophagy (6) Bacterial (6) Biochemical Assay Reagents (1) Btk (1) CaMK (1) CD3 (5) CD38 (1) CD47 (3) Claudin (1) CMV (1) DNA Alkylator/Crosslinker (1) DNA/RNA Synthesis (1) Drug Intermediate (2) Drug Metabolite (1) EGFR (1) Ferroptosis (4) FGFR (1) Fungal (2) GABA Receptor (2) Gap Junction Protein (1) Interleukin Related (2) Isotope-Labeled Compounds (1) Itk (1) Keap1-Nrf2 (1) LDLR (1) Liposome (1) Melanocortin Receptor (3) MHC (1) p38 MAPK (1) Parasite (2) PD-1/PD-L1 (2) Phosphodiesterase (PDE) (1) Phospholipase (1) PPAR (19) PROTACs (3) Reference Standards (5) ROR (1) SARS-CoV (1) TNF Receptor (5) Trk Receptor (1) TRP Channel (4) Wnt (1)
By Research Areas:	Cancer (29) Cardiovascular Disease (8) Endocrinology (1) Infection (7) Inflammation/Immunology (20) Metabolic Disease (24) Neurological Disease (5)
Oligonucleotides:	Phospholipids (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1214

γ1-MSH	Melanocortin Receptor	Cardiovascular Disease
γ1-MSH is a melanocortin MC3 receptor agonist, with a K_i of 34 nM for the rat MC3 receptor. γ1-MSH displays ~40-fold selectivity over MC4 (K_i=1318 nM) ^[1].

HY-19609

Calicheamicin 5+ Cited Publications Calicheamicin γ1	DNA Alkylator/Crosslinker ADC Payload Bacterial Apoptosis Antibiotic	Infection Cancer
Calicheamicin, an antitumor antibiotic, is a cytotoxic agent that causes double-strand DNA breaks. Calicheamicin is a DNA synthesis inhibitor ^[1]. Calicheamicin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P991027

Spevatamig	CD47	Inflammation/Immunology
HY-P991027 is an CD47/CLDN18-targeting (H-γ1_L-κ)_(H-γ1_L-κ) type bispecific antibody ^[1].

HY-N1773

5,7,3'-Tri-O-methyl (-)-epicatechin	Others	Cancer
5,7,3' -tri-O-Methyl (-)-epicatechin (Compound 13) is a phospholipase Cγ1 (PLCγ1) inhibitor. 5,7,3' -tri-o-methyl (-)-epicatechin has a methylene dioxy benzene ring and can express inhibitory activity against PLCγ1. 5,7,3' -tri-O-Methyl (-)-epicatechin can be used in the study of chemotherapy and chemopexic agents for cancer ^[1].

HY-P991036

Velinotamig GR-1803	TNF Receptor	Inflammation/Immunology
HY-P991036 is an CD3E/TNFRSF17-targeting H-γ1_L-κ/H-γ1_L-κ type bispecific antibody ^[1].

HY-N14490

Coumamidine γ1	Antibiotic Bacterial	Infection
Coumamidine γ1 is a kind of alkaline sugar Cinodine antibiotic, which has broad spectrum antibacterial activity and also has effect on pseudomonas aeruginosa ^[1].

HY-P1214A

γ1-MSH TFA	Melanocortin Receptor	Cardiovascular Disease
γ1-MSH TFA is a melanocortin MC3 receptor agonist, with a K_i of 34 nM for the rat MC3 receptor. γ1-MSH TFA displays ~40-fold selectivity over MC4 (K_i=1318 nM) ^[1].

HY-P990161

Anti-Mouse TCR Vγ1.1/Cr4 Antibody (2.11)	MHC	Inflammation/Immunology Cancer
Anti-Mouse TCR Vγ1.1/Cr4 Antibody (2.11) is an anti-mouse TCR Vγ1.1/Cr4 IgG monoclonal antibody. Anti-Mouse TCR Vγ1.1/Cr4 Antibody (2.11) can deplete Vγ1 γδ T cells. Anti-Mouse TCR Vγ1.1/Cr4 Antibody (2.11) can be used for research on cancer and inflammation conditions such as mastitis and colon cancer ^[1] .

HY-E70796

Biotin-AMPKα2β1γ1 Recombinant Human Active Protein Kinase	AMPK	Cancer
AMPK is an αβγ heterotrimeric serinethreonine kinase activated by decreasing concentrations of adenosine triphosphate (ATP) and increasing AMP concentrations. Biotin-AMPKα2β1γ1 Recombinant Human Active Protein Kinase is obtained by co-expressing AMPKα2, AMPKβ1, and AMPKγ1 proteins and is biotinylated ^[1].

HY-E70795

Biotin-AMPKα1β2γ1 Recombinant Human Active Protein Kinase	AMPK	Cancer
AMPK is an αβγ heterotrimeric serinethreonine kinase activated by decreasing concentrations of adenosine triphosphate (ATP) and increasing AMP concentrations. Biotin-AMPKα1β2γ1 Recombinant Human Active Protein Kinase is obtained by co-expressing AMPKα1, AMPKβ2, and AMPKγ1 proteins and is biotinylated ^[1].

HY-E70793

Biotin-AMPKα1β1γ1 Recombinant Human Active Protein Kinase	AMPK	Cancer
AMPK is an αβγ heterotrimeric serinethreonine kinase activated by decreasing concentrations of adenosine triphosphate (ATP) and increasing AMP concentrations. Biotin-AMPKα1β1γ1 Recombinant Human Active Protein Kinase is obtained by co-expressing AMPKα1, AMPKβ1, and AMPKγ1 proteins and is biotinylated ^[1].

HY-P990972

Azerutamig	EGFR	Inflammation/Immunology
HY-P990972 is an *KLRK1/ERBB2*-targeting (H-γ1_L-κ)_scFvkh-H-γ1(h-CH2-CH3) type bispecific antibody ^[1].

HY-E70787

AMPK α1β1γ1 Recombinant Human Active Protein Kinase	AMPK	Cancer
AMPK is an αβγ heterotrimeric serinethreonine kinase activated by decreasing concentrations of adenosine triphosphate (ATP) and increasing AMP concentrations. AMPK α1β1γ1 Recombinant Human Active Protein Kinase is an ortholog of AMPK. AMPK α1β1γ1 Recombinant Human Active Protein Kinase is obtained by co-expressing AMPKα1, AMPKβ1, and AMPKγ1 proteins ^[1].

HY-101649

Imiglitazar TAK-559	PPAR	Cardiovascular Disease
Imiglitazar (TAK559) is a potent and dual human PPARα and PPARγ1 agonist with EC₅₀ values of 67 and 31 nM.

HY-P990021

Calpurbatug	Bacterial	Others
Calpurbatug is an immunoglobulin G1 antibody. Calpurbatug has activity with anti-bacterial DNA-binding protein DNABII family and anti-human monoclonal TRL1068 γ1-chain ^[1].

HY-P991700

Lumivatamig	Claudin CD3	Cancer
Lumivatamig is an H-γ1_L-κ-scFvhl dimer-type bispecific antibody targeting CLDN18.2 & CD3E ^[1].

HY-P991016

Peluntamig PT-217	CD47	Inflammation/Immunology
HY-P991016 is an CD47/DLL3-targeting H-γ1_L-κ type bispecific antibody ^[1].

HY-P991034

Trevotamig	CD3	Inflammation/Immunology
HY-P991034 is an EPCAM/CD3E-targeting H-γ1_L-κ-scFvhl dimer type bispecific antibody ^[1].

HY-P990903

Avitotamig	CD3	Inflammation/Immunology
HY-P990903 is an CD3E/CD33-targeting [H-γ1 _ L-κ-scFv heavy -κ]-dimer type bispecific antibody ^[1].

HY-P991147

Ledostomig	PD-1/PD-L1	Cancer
Ledostomig is an immunoglobulin (H-γ1-scFv-L-κ) dimer monoclonal antibody targeting human netrin-5 (NTS5) and programmed death-1 (PD-1). Ledostomig is promising for research of various cancers ^[1].

HY-P990980

Cizutamig CND-106; EMB-06	TNF Receptor	Inflammation/Immunology
HY-P990980 is an TNFRSF17-targeting [L-κ-H-γ1_[VH-G1(CH1-h)]_Lκ] dimer type humanized antibody ^[1].

HY-P991004

Itanistomig	CD47	Inflammation/Immunology
HY-P991004 is an CD274/CD47-targeting (VH-G1CH1-h)-H-γ1_L-κ-L-κ type bispecific antibody ^[1].

HY-P991015

Pasritamig	CD3	Inflammation/Immunology
HY-P991015 is an KLK2/CD3E-targeting (H-γ1_L-κ)_scFvkh-G1(h-CH2-CH3) type bispecific antibody ^[1].

HY-P990905

Bexatamig SAR-443579	Interleukin Related	Inflammation/Immunology
HY-P990905 is an *IL3RA/NCR1*-targeting [(H-γ1-VH-CH1-h_L-κ)_L-κ-h-CH2-CH3] type bispecific antibody ^[1].

HY-N0084

Betulinaldehyde 5 Publications Verification Betulinic aldehyde; Betunal	Bacterial	Infection Cardiovascular Disease Cancer
Betulinaldehyde (Betunal) Has anti-cancer and anti-staphylococcus aureus activity. Betulinaldehyde Suppressible Akt, MAPK sum STAT3 Signal path, increase self-transfer, Suppression A549 Cellular vitality, increase and transfer. Betulinaldehyde suppresses PLCγ1/Ca ²⁺/MMP9 signal pathway, has a key effect on vascular plasticity, and is available for cardiovascular disease (CVD) research.

HY-146672

ITK inhibitor 6	Itk	Cancer
ITK inhibitor 6 (compound 43) is a potent and selective ITK inhibitor with IC₅₀s of 4 nM, 133 nM, 320 nM, 2360 nM, 155 nM for ITK, BTK, JAK3, EGFR, LCK, respectively. ITK inhibitor 6 inhibits phosphorylation of PLCγ1 and ERK1/2. ITK inhibitor 6 shows antiproliferative activities ^[1].

HY-P991151

Opamtistomig	PD-1/PD-L1 TNF Receptor	Cancer
Opamtistomig is a humanized immunoglobulin (H-γ1-scFv-L-κ) dimer monoclonal antibody targeting human programmed death ligand 1 (PD-L1), CD274 and tumor necrosis factor receptor superfamily member 9 (TNFRSF9). Opamtistomig is promising for research of various solid tumors and hematological malignancies ^[1].

HY-P9991

Osemitamab TST001	Gap Junction Protein	Cancer
Osemitamab is an IgG1 antibody targeting to human claudin-18.2. Osemitamab consists of human-Mus musculus monoclonal TST001 γ1-chain, disulfide with human-Mus musculus monoclonal TST001 κ-chain, dimer (ACI). Osemitamab in combination with Capecitabine (HY-B0016) and Oxaliplatin (HY-17371), can be used for G/GEJ cancer study ^[1] .

HY-B0700

Rosiglitazone sodium BRL 49653 sodium	PPAR TRP Channel Autophagy	Metabolic Disease Inflammation/Immunology
Rosiglitazone sodium is a potent and selective activator of PPARγ, with EC₅₀s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively, and a K_d of appr 40 nM for PPARγ; Rosiglitazone sodium is also an modulator of TRP channels, inhibits TRP melastatin 2 (TRPM2), TRPM3 and activates TRP canonical 5 (TRPC5).

HY-14600

Rosiglitazone maleate Maximum Cited Publications 143 Publications Verification BRL 49653C	PPAR TRP Channel Autophagy Ferroptosis	Metabolic Disease Inflammation/Immunology Cancer
Rosiglitazone maleate (BRL 49653C) is a potent and selective activator of PPARγ, with EC₅₀s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively, and a K_d of appr 40 nM for PPARγ; Rosiglitazone maleate is also an modulator of TRP channels, inhibits TRP melastatin 2 (TRPM2), TRPM3 and activates TRP canonical 5 (TRPC5).

HY-P991149

Nesfrotamig	TNF Receptor	Cancer
Nesfrotamig is a humanized immunoglobulin (H-γ1-scFv-L-κ) dimer monoclonal antibody targeting human epidermal growth factor receptor 2 (ERBB2) and human tumor necrosis factor receptor superfamily member 9 (TNFRSF9). Nesfrotamig is promising for research of cancers, especially in ERBB2-positive related tumor diseases, such as breast cancer and gastric cancer ^[1].

HY-14600R

Rosiglitazone maleate (Standard) BRL 49653C (Standard)	Reference Standards PPAR TRP Channel Autophagy Ferroptosis	Metabolic Disease Inflammation/Immunology Cancer
Rosiglitazone (maleate) (Standard) is the analytical standard of Rosiglitazone (maleate). This product is intended for research and analytical applications. Rosiglitazone maleate (BRL 49653C) is a potent and selective activator of PPARγ, with EC₅₀s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively, and a K_d of appr 40 nM for PPARγ; Rosiglitazone maleate is also an modulator of TRP channels, inhibits TRP melastatin 2 (TRPM2), TRPM3 and activates TRP canonical 5 (TRPC5).

HY-135799

WH-15	Phospholipase	Neurological Disease Cancer
WH-15 is a fluorogenic PLC reporter with K_m value of 49; 30, 86.1 µM for PLC-γ1, PLC-δ1, PLC-β2, respectively. WH-15 can be cleaved in a cascade reaction to generate fluorescent 6-aminoquinoline. WH-15 can be used to respond to imaging PLC activity in live cells (Ex/Em = ~344/530 nm) ^[1].

HY-17386S

Rosiglitazone-d3	Isotope-Labeled Compounds PPAR TRP Channel Autophagy Ferroptosis	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Rosiglitazone-d₃ is the deuterium labeled Rosiglitazone. Rosiglitazone (BRL 49653) is a selective, orally active PPARγ agonist with EC₅₀s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively. Rosiglitazone binds to PPARγ with a Kd of approximately 40 nM. Rosiglitazone is also an activator of TRPC5 (EC₅₀=~30 μM) and an inhibitor of TRPM3 ^[1] .

HY-B1803A

Tracazolate hydrochloride ICI 136753 hydrochloride	GABA Receptor	Neurological Disease
Tracazolate (ICI 136753) hydrochloride is a potent GABA_A receptor modulator. Tracazolate hydrochloride has selectivity for β3 and potentiates α1β1γ2s (EC₅₀=13.2 μM), α1β3γ2 (EC₅₀=1.5 μM). Tracazolate hydrochloride has the potency (EC₅₀) determined by the nature of the third subunit (γ1-3, δ, ε) within the receptor complex. Tracazolate hydrochloride possesses anxiolytic and anticonvulsant activity ^[1] .

HY-178335

SGC-CK1γ-1	LDLR Wnt CMV	Infection
SGC-CK1γ-1 is a potent and selective probe for the CK1γ subfamily. SGC-CK1γ-1 can inhibit LRP6 phosphorylation levels. SGC-CK1γ-1 can selectively inhibit the CK1γ kinases in living cells and inhibit both WNT signaling and human cytomegalovirus (CMV) replication. SGC-CK1γ-1 can be used for the research of infection ^[1].

HY-P1531

γ-1-Melanocyte Stimulating Hormone (MSH), amide	Melanocortin Receptor	Cardiovascular Disease Metabolic Disease Endocrinology
γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na ⁺) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R).

HY-157129

AMPK-α1β1γ1 activator 1	AMPK	Cardiovascular Disease
AMPK-α1β1γ1 activator 1 (M1) is an acyl glucuronide metabolite of Indole-3-carboxylic Acid-based AMPK activator. AMPK-α1β1γ1 activator 1 can selectively activated human β1 isoforms with an EC₅₀ value of 38.1nM. AMPK-α1β1γ1 activator 1 can direct binding with human AMPK α1β1γ1 isoform. AMPK-α1β1γ1 activator 1 can be used for the research of diabetic nephropathy ^[1].

HY-151920

BTK-IN-17	Btk	Inflammation/Immunology
BTK-IN-17 (compound 36R) is a selective and orally activeBTK inhibitor with an IC₅₀ value of 13.7 nM. BTK-IN-17 decreases the expression of p-BTK ^Y223 and p-PLCγ2 ^Y1217. BTK-IN-17 shows anti-inflammatory effects ^[1].

HY-16708A

ZLN024 hydrochloride 1 Publications Verification	AMPK	Metabolic Disease
ZLN024 hydrochloride is an AMPK allosteric activator. ZLN024 directly activates recombinant AMPK α1β1γ1, AMPK α2β1γ1, AMPK α1β2γ1 and AMPK α2β2γ1 heterotrimer with EC₅₀s of 0.42 µM, 0.95 µM, 1.1 µM and 0.13 µM, respectively.

HY-16708

ZLN024	AMPK	Metabolic Disease
ZLN024 is an AMPK allosteric activator. ZLN024 directly activates recombinant AMPK α1β1γ1, AMPK α2β1γ1, AMPK α1β2γ1 and AMPK α2β2γ1 heterotrimer with EC₅₀s of 0.42 µM, 0.95 µM, 1.1 µM and 0.13 µM, respectively.

HY-112769

EX229 5 Publications Verification	AMPK	Metabolic Disease
EX229, a Benzimidazole derivative, is a potent and allosteric activator of AMP-activated protein kinase (AMPK), with K_ds of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1 and α1β2γ1 in biolayer interferometry, respectively.

HY-147038

AMPK activator 8	AMPK	Metabolic Disease
AMPK activator 8 (compound 2) is an AMP-activated protein kinase (AMPK) activator with EC₅₀s of 11, 27, 4, 2, and 4 nM for rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ1, rAMPK α2β2γ3, respectively. AMPK activator 8 can be used for the research of type 2 diabetes ^[1].

HY-49076

RORγ inverse agonist 1	ROR	Cancer
RORγ inverse agonist 1 is the inverse agonist of RORγ .

HY-158934

(±)-CBCQ Cannabichromenquinone	PPAR	Others
(±)-CBCQ is an oxidative product of cannabichromene, with an EC₅₀ of 14.7 μM for *PPAR-γ* .

HY-120270

PF-06679142	AMPK	Metabolic Disease
PF-06679142 (Compound 10) is a potent, orally active AMPK activator with an EC₅₀ of 22 nM against *α1β1γ1-AMPK*. PF-06679142 can be used for diabetic nephropathy research ^[1].

HY-14728S

Deutaleglitazar Aleglitazar-d₂; R1439-d₂; RO0728804-d₂	PPAR	Others
Deutaleglitazar (Aleglitazar-d₂) is a agonist of dual peroxisome proliferatory activating receptor (PPARα and PPARγ) .

HY-14817

Indeglitazar PPM 204	PPAR	Metabolic Disease
Indeglitazar (PPM 204) is an orally available PPAR pan-agonist for all three PPARα, PPARδ and PPARγ .

HY-163985

PROTAC FGFR2 degrader 1	PROTACs FGFR Apoptosis	Cancer
PROTAC FGFR2 degrader 1 (compound N5) is a PROTAC that effectively targets FGFR2 with DC₅₀ of 6.46 nM, the FGFR2 IC₅₀ is 0.08 nM. PROTAC FGFR2 degrader 1 has anti-proliferative activity and highly selective, induces G0/G1 arrest of KATOIII and SNU16 cell cycle and inhibits apoptosis by reducing the activation of p-ERK and p-PLCγ, the downstream proteins of FGFR2. PROTAC FGFR2 degrader 1 inhibits gastric cancer cells remained above 50% at a concentration of 0.17 nM. PROTAC FGFR2 degrader 1 potently inhibits the growth of SNU16 xenograft tumors in mouse model (Structure Note: Pink, FGFR2 activator: HY-18708; Blue, E3 ligase ligand: HY--10984; Black, linker: HY-163989; E3 ligase ligand + linker：HY-163986) ^[1].

HY-N2209

Angeloylgomisin H	PPAR	Metabolic Disease
Angeloylgomisin H, as a major lignin extract of Schisandra rubriflora, has the potential to improve insulin-stimulated glucose uptake by activating *PPAR-γ* .

Cat. No.	Product Name	Target	Research Area

HY-P991027

Spevatamig	CD47	Inflammation/Immunology
HY-P991027 is an CD47/CLDN18-targeting (H-γ1_L-κ)_(H-γ1_L-κ) type bispecific antibody ^[1].

HY-P991036

Velinotamig GR-1803	TNF Receptor	Inflammation/Immunology
HY-P991036 is an CD3E/TNFRSF17-targeting H-γ1_L-κ/H-γ1_L-κ type bispecific antibody ^[1].

HY-P990021

Calpurbatug	Bacterial	Others
Calpurbatug is an immunoglobulin G1 antibody. Calpurbatug has activity with anti-bacterial DNA-binding protein DNABII family and anti-human monoclonal TRL1068 γ1-chain ^[1].

HY-P990161

Anti-Mouse TCR Vγ1.1/Cr4 Antibody (2.11)	MHC	Inflammation/Immunology Cancer
Anti-Mouse TCR Vγ1.1/Cr4 Antibody (2.11) is an anti-mouse TCR Vγ1.1/Cr4 IgG monoclonal antibody. Anti-Mouse TCR Vγ1.1/Cr4 Antibody (2.11) can deplete Vγ1 γδ T cells. Anti-Mouse TCR Vγ1.1/Cr4 Antibody (2.11) can be used for research on cancer and inflammation conditions such as mastitis and colon cancer ^[1] .

HY-P990972

Azerutamig	EGFR	Inflammation/Immunology
HY-P990972 is an *KLRK1/ERBB2*-targeting (H-γ1_L-κ)_scFvkh-H-γ1(h-CH2-CH3) type bispecific antibody ^[1].

HY-P991700

Lumivatamig	Claudin CD3	Cancer
Lumivatamig is an H-γ1_L-κ-scFvhl dimer-type bispecific antibody targeting CLDN18.2 & CD3E ^[1].

HY-P991016

Peluntamig PT-217	CD47	Inflammation/Immunology
HY-P991016 is an CD47/DLL3-targeting H-γ1_L-κ type bispecific antibody ^[1].

HY-P991034

Trevotamig	CD3	Inflammation/Immunology
HY-P991034 is an EPCAM/CD3E-targeting H-γ1_L-κ-scFvhl dimer type bispecific antibody ^[1].

HY-P990903

Avitotamig	CD3	Inflammation/Immunology
HY-P990903 is an CD3E/CD33-targeting [H-γ1 _ L-κ-scFv heavy -κ]-dimer type bispecific antibody ^[1].

HY-P991147

Ledostomig	PD-1/PD-L1	Cancer
Ledostomig is an immunoglobulin (H-γ1-scFv-L-κ) dimer monoclonal antibody targeting human netrin-5 (NTS5) and programmed death-1 (PD-1). Ledostomig is promising for research of various cancers ^[1].

HY-P990980

Cizutamig CND-106; EMB-06	TNF Receptor	Inflammation/Immunology
HY-P990980 is an TNFRSF17-targeting [L-κ-H-γ1_[VH-G1(CH1-h)]_Lκ] dimer type humanized antibody ^[1].

HY-P991004

Itanistomig	CD47	Inflammation/Immunology
HY-P991004 is an CD274/CD47-targeting (VH-G1CH1-h)-H-γ1_L-κ-L-κ type bispecific antibody ^[1].

HY-P991136

Etuptamig	Inhibitory Antibodies	Cancer
Etuptamig is a chimeric monoclonal antibody of immunoglobulin λ-chain-γ1, λ-chain-γ3 targeting human natural killer cell cytotoxicity receptor 1 (NCR1). Etuptamig is promising for research of various cancers ^[1].

HY-P991015

Pasritamig	CD3	Inflammation/Immunology
HY-P991015 is an KLK2/CD3E-targeting (H-γ1_L-κ)_scFvkh-G1(h-CH2-CH3) type bispecific antibody ^[1].

HY-P990905

Bexatamig SAR-443579	Interleukin Related	Inflammation/Immunology
HY-P990905 is an *IL3RA/NCR1*-targeting [(H-γ1-VH-CH1-h_L-κ)_L-κ-h-CH2-CH3] type bispecific antibody ^[1].

HY-P991151

Opamtistomig	PD-1/PD-L1 TNF Receptor	Cancer
Opamtistomig is a humanized immunoglobulin (H-γ1-scFv-L-κ) dimer monoclonal antibody targeting human programmed death ligand 1 (PD-L1), CD274 and tumor necrosis factor receptor superfamily member 9 (TNFRSF9). Opamtistomig is promising for research of various solid tumors and hematological malignancies ^[1].

HY-P9991

Osemitamab TST001	Gap Junction Protein	Cancer
Osemitamab is an IgG1 antibody targeting to human claudin-18.2. Osemitamab consists of human-Mus musculus monoclonal TST001 γ1-chain, disulfide with human-Mus musculus monoclonal TST001 κ-chain, dimer (ACI). Osemitamab in combination with Capecitabine (HY-B0016) and Oxaliplatin (HY-17371), can be used for G/GEJ cancer study ^[1] .

HY-P991149

Nesfrotamig	TNF Receptor	Cancer
Nesfrotamig is a humanized immunoglobulin (H-γ1-scFv-L-κ) dimer monoclonal antibody targeting human epidermal growth factor receptor 2 (ERBB2) and human tumor necrosis factor receptor superfamily member 9 (TNFRSF9). Nesfrotamig is promising for research of cancers, especially in ERBB2-positive related tumor diseases, such as breast cancer and gastric cancer ^[1].

HY-P991706

Nelvutamig	Phosphodiesterase (PDE) CD3	Cancer
Nelvutamig is a humanized immunoglobulin (H-gamma1_L-kappa)_scFvkh-G1(h-CH2-CH3) antibody targeting ENPP3/CD203c and CD3E. The corresponding isotype control is: Human immunoglobulin (H-gamma1_L-kappa)_scFvkh-G1(h-CH2-CH3) ^[1].

HY-P99325

Toralizumab IDEC-131; Anti-Human CD40 ligand Recombinant Antibody	TNF Receptor	Inflammation/Immunology
Toralizumab (IDEC-131) is a humanized monoclonal antibody (mAb) against CD40L (CD154) comprised of human gamma 1 heavy chains and human kappa light chains. Toralizumab binds specifically to human CD40L on T cells, thereby preventing CD40 signaling. Toralizumab is an immunosuppressive agent. Toralizumab can lead to increased thrombosis. Toralizumab can be studied in research for diseases such as multiple sclerosis, systemic lupus erythematosus (SLE), and Crohn’s disease ^[1] .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1773

5,7,3'-Tri-O-methyl (-)-epicatechin	Machilus thunbergii Sieb. et Zucc. Flavonoids Flavanols Source classification Plants Lauraceae	Others
5,7,3' -tri-O-Methyl (-)-epicatechin (Compound 13) is a phospholipase Cγ1 (PLCγ1) inhibitor. 5,7,3' -tri-o-methyl (-)-epicatechin has a methylene dioxy benzene ring and can express inhibitory activity against PLCγ1. 5,7,3' -tri-O-Methyl (-)-epicatechin can be used in the study of chemotherapy and chemopexic agents for cancer ^[1].

HY-N0084

Betulinaldehyde 5 Publications Verification Betulinic aldehyde; Betunal	Triterpenes other families Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Cancer	Bacterial
Betulinaldehyde (Betunal) Has anti-cancer and anti-staphylococcus aureus activity. Betulinaldehyde Suppressible Akt, MAPK sum STAT3 Signal path, increase self-transfer, Suppression A549 Cellular vitality, increase and transfer. Betulinaldehyde suppresses PLCγ1/Ca ²⁺/MMP9 signal pathway, has a key effect on vascular plasticity, and is available for cardiovascular disease (CVD) research.

HY-N2209

Angeloylgomisin H	Classification of Application Fields Source classification Lignans Metabolic Disease Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Disease Research Fields	PPAR
Angeloylgomisin H, as a major lignin extract of Schisandra rubriflora, has the potential to improve insulin-stimulated glucose uptake by activating *PPAR-γ* .

HY-W341997

9-Octadecynoic acid	Leguminosae Paramacrolobium coeruleum (Taub.) J.Léonard Ketones, Aldehydes, Acids Source classification Plants	PPAR
9-Octadecynoic acid is a DNA binding agent with a dissociation constant of 1.8 mM. 9-Octadecynoic acid is also an agonist for peroxisome proliferator-activated receptor γ (PPARγ) .

HY-N3027

Soyasaponin Aa	Triterpenes Classification of Application Fields Leguminosae Glycine max (L.) merr Terpenoids Source classification Metabolic Disease Plants Disease Research Fields	PPAR
Soyasaponin Aa is a soyasaponin that exerts an anti-obesity effect in 3T3-L1 adipocytes through downregulation of peroxisome proliferator-activated receptor γ (PPARγ) .

HY-N14490

Coumamidine γ1	Natural Products Microorganisms Source classification	Antibiotic Bacterial
Coumamidine γ1 is a kind of alkaline sugar Cinodine antibiotic, which has broad spectrum antibacterial activity and also has effect on pseudomonas aeruginosa ^[1].

HY-B1419R

Salicyl alcohol (Standard) 2-Hydroxybenzyl alcohol (Standard); Saligenin (Standard)	Monophenols Microorganisms Source classification Phenols	Drug Intermediate Reference Standards
Soyasaponin Aa (Standard) is the analytical standard of Soyasaponin Aa. This product is intended for research and analytical applications. Soyasaponin Aa is a soyasaponin that exerts an anti-obesity effect in 3T3-L1 adipocytes through downregulation of peroxisome proliferator-activated receptor γ (PPARγ) .

HY-N3027R

Soyasaponin Aa (Standard)	Triterpenes Leguminosae Glycine max (L.) merr Terpenoids Source classification Plants	Reference Standards PPAR
Soyasaponin Aa (Standard) is the analytical standard of Soyasaponin Aa. This product is intended for research and analytical applications. Soyasaponin Aa is a soyasaponin that exerts an anti-obesity effect in 3T3-L1 adipocytes through downregulation of peroxisome proliferator-activated receptor γ (PPARγ) .

Species:	Human (29) Mouse (2) Staphylococcus aureus (1)
Tag:	His (18) Tag Free (9) Avi (3) Myc (1) GST (8)
Source:	HEK293 (18) CHO (1) Sf9 insect cells (10) P. pastoris (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P76141

	*AMPK gamma 1/beta 1/alpha 1 Heterotrimer Protein, Human (sf9, His-GST)* 1 Publications Verification 5'-AMP-activated protein kinase; AMPK; AMPK (α1, β1, γ1) Protein	Human	Sf9 insect cells
	AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK) and is an important regulator of cellular energy metabolism. It is activated by low ATP levels, enhancing energy production while inhibiting biosynthetic processes and cell growth. AMPK gamma 1/beta 1/alpha 1 Heterotrimer Protein, Human (sf9, His-GST) is the recombinant human-derived AMPK gamma 1/beta 1/alpha 1 Heterotrimer protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. AMPK gamma 1/beta 1/alpha 1 Heterotrimer Protein, Human (sf9, His-GST), has molecular weight of 38 (beta-1)&40 (gamma-1)&95 (alpha-1) kDa, respectively.

HY-P76142

	*AMPK gamma 1/beta 1/alpha 2 Heterotrimer Protein, Human (sf9, His-GST)* 5'-AMP-activated protein kinase; AMPK; AMPK (α2, β1, γ1) Protein	Human	Sf9 insect cells
	AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK) and is an important regulator of cellular energy metabolism. It is activated by low ATP levels, enhancing energy production while inhibiting biosynthetic processes and cell growth. AMPK gamma 1/beta 1/alpha 2 Heterotrimer Protein, Human (sf9, His-GST) is the recombinant human-derived AMPK gamma 1/beta 1/alpha 2 Heterotrimer protein, expressed by Sf9 insect cells , with N-His, N-GST, N-10*His labeled tag. AMPK gamma 1/beta 1/alpha 2 Heterotrimer Protein, Human (sf9, His-GST), has molecular weight of ~40 & 42 & 95 KDa, respectively.

HY-P76143

	*AMPK gamma 1/beta 2/alpha 1 Heterotrimer Protein, Human (sf9, His-GST)* 5'-AMP-activated protein kinase; AMPK; AMPK (α1, β2, γ1) Protein	Human	Sf9 insect cells
	AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK) and is an important regulator of cellular energy metabolism. It is activated by low ATP levels, enhancing energy production while inhibiting biosynthetic processes and cell growth. AMPK gamma 1/beta 2/alpha 1 Heterotrimer Protein, Human (sf9, His-GST) is the recombinant human-derived AMPK gamma 1/beta 2/alpha 1 Heterotrimer protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. AMPK gamma 1/beta 2/alpha 1 Heterotrimer Protein, Human (sf9, His-GST), has molecular weight of ~35 & 37 & 95 KDa, respectively.

HY-P76144

	*AMPK gamma 1/beta 2/alpha 2 Heterotrimer Protein, Human (sf9, His-GST)* 5'-AMP-activated protein kinase; AMPK; AMPK (α2, β2, γ1) Protein	Human	Sf9 insect cells
	AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK) and is an important regulator of cellular energy metabolism. It is activated by low ATP levels, enhancing energy production while inhibiting biosynthetic processes and cell growth. AMPK gamma 1/beta 2/alpha 2 Heterotrimer Protein, Human (sf9, His-GST) is the recombinant human-derived AMPK gamma 1/beta 2/alpha 2 Heterotrimer protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. AMPK gamma 1/beta 2/alpha 2 Heterotrimer Protein, Human (sf9, His-GST), has molecular weight of ~35 & 37 & 95 KDa, respectively.

HY-P71635

	SNTG1 Protein, Human (Myc, His) G1SYN; Gamma 1 syntrophin; SNTG 1; Sntg1; SNTG1_HUMAN; SYN 4; SYN4; Synotrophin gamma 1; Syntrophin 4; Syntrophin gamma 1; Syntrophin-4	Human	E. coli
	SNTG1 acts as an adapter protein that binds and potentially organizes various proteins, serving as a link between the receptor and the actin cytoskeleton or dystrophin glycoprotein complex. It may modulate the subcellular distribution of diacylglycerol kinase-zeta and contribute to the rapid inactivation of diacylglycerol upon receptor activation. SNTG1 Protein, Human (Myc, His) is the recombinant human-derived SNTG1 protein, expressed by E. coli , with N-His, C-Myc labeled tag.

HY-P702669

	CSNK1G1 Protein, Human (sf9, GST) Casein kinase I isoform gamma-1; CKI-gamma 1	Human	Sf9 insect cells
	The CSNK1G1 protein is a member of the casein kinase family that preferentially phosphorylates acidic proteins, including casein, exhibiting broad substrate specificity. Functionally, it actively participates in the Wnt signaling pathway and regulates cellular responses. CSNK1G1 Protein, Human (sf9, GST) is the recombinant human-derived CSNK1G1, expressed by Sf9 insect cells, with GST labeled tag. The total length of CSNK1G1 Protein, Human (sf9, GST) is 421 a.a..

HY-P76850

	CSNK1G1 Protein, Human (sf9, His-GST) Casein kinase I isoform gamma-1; CKI-gamma 1	Human	Sf9 insect cells
	The CSNK1G1 protein is a member of the casein kinase family that preferentially phosphorylates acidic proteins, including casein, exhibiting broad substrate specificity. Functionally, it actively participates in the Wnt signaling pathway and regulates cellular responses. CSNK1G1 Protein, Human (sf9, His-GST) is the recombinant human-derived CSNK1G1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P71731

	EIF4G1 Protein, Human (P.pastoris, His) eIF 4 gamma 1; eIF 4G 1; eIF 4G1; eIF-4-gamma 1; EIF4G; Eukaryotic translation initiation factor 4 gamma 1	Human	P. pastoris
	EIF4G1 is a key component of the eIF4F complex and plays a critical regulatory role in translation initiation. EIF4G1 plays different roles in complexes with EIF1 or EIF4E. EIF4G1 Protein, Human (P.pastoris, His) is the recombinant human-derived EIF4G1 protein, expressed by P. pastoris , with N-His labeled tag.

HY-P705482

	ICOS Protein, Human (HEK293, His) Immunoglobulin heavy constant gamma 1; IGHG1	Human	HEK293

HY-P702665

	PHKG1 Protein, Human (Active, sf9, GST) PHKG1; phosphorylase kinase, gamma 1 (muscle); phosphorylase kinase, gamma 1 (muscle); phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform; phosphorylase kinase gamma; phosphorylase kinase subunit gamma-1; EC 2.7.11.19	Human	Sf9 insect cells
	PHKG1 is the catalytic subunit of phosphorylase b kinase (PHK), which plays a key role in the neural and hormonal regulation of glycogenolysis (glycogen breakdown) by phosphorylating and activating glycogen phosphorylase. PHKG1 Protein, Human (Active, sf9, GST) is the recombinant human-derived PHKG1, expressed by Sf9 insect cells, with GST labeled tag.

HY-P702979

	AMPKG1 Protein, Human (sf9, GST) 5'-AMP-activated protein kinase subunit gamma-1; AMPK gamma1; AMPK subunit gamma-1; AMPKg; PRKAG1	Human	Sf9 insect cells
	AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK) and is an important regulator of cellular energy metabolism. It is activated by low ATP levels, enhancing energy production while inhibiting biosynthetic processes and cell growth. AMPKG1 Protein, Human (sf9, GST) is the recombinant human-derived AMPKG1, expressed by Sf9 insect cells, with GST labeled tag. The total length of AMPKG1 Protein, Human (sf9, GST) is 331 a.a..

HY-P73903

	IgG1 Protein, Human (CHO, C103S) Immunoglobulin heavy constant gamma 1; IGHG1	Human	CHO
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (CHO, C103S) is the recombinant human-derived IgG1 protein, expressed by CHO , with tag free.

HY-P73143

	IgG1 Protein, Human (C103S, HEK293) 1 Publications Verification Immunoglobulin heavy constant gamma 1; IGHG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (C103S, HEK293) is the recombinant human-derived IgG1 protein, expressed by HEK293 , with tag free.

HY-P73901

	IgG1 Protein, Mouse (HEK293, C102S) Immunoglobulin heavy constant gamma 1; IGHG1	Mouse	HEK293
	IgG1 Protein is the most abundant Immunoglobulin G (IgG) subclass in human sera and is important for mediating antibody responses against viral pathogens. IgG1 enables antigen binding activity and immunoglobulin receptor binding activity. It acts upstream of or within several processes, including antibody-dependent cellular cytotoxicity, phagocytosis, and positive regulation of immune response. IgG1 Protein, Mouse (HEK293, C102S) is the recombinant mouse-derived IgG1 protein, expressed by HEK293 , with tag free.

HY-P77526

	IgG1 Protein, Human (Biotinylated, C103S, HEK293) Immunoglobulin heavy constant gamma 1; IGHG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (Biotinylated, C103S, HEK293) is the recombinant human-derived IgG1 protein, expressed by HEK293 , with tag free.

HY-P70763

	IgG1 Protein, Mouse (HEK293) Ig gamma-1 chain C region; IGHG1	Mouse	HEK293
	The immunoglobulin heavy chain constant region is the heavy chain constant region of immunoglobulin. Sequence differences between immunoglobulin heavy chains leads to the various isotypes with different characteristic. IgG1 Protein, Mouse (HEK293) is the recombinant mouse-derived IgG1 protein, expressed by HEK293 , with tag free.

HY-P704685

	IgG1 Protein, Human (HEK293, His) Ig gamma-1 chain C region; IGHG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (HEK293, His) is the recombinant human-derived IgG1 protein, expressed by HEK293, with C-His labeled tag.

HY-P72379

	IgG1 Protein, Human (Biotinylated, HEK293, Avi) Ig gamma-1 chain C region; IGHG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (Biotinylated, HEK293, Avi) is the recombinant human-derived IgG1 protein, expressed by HEK293 , with C-Avi labeled tag.

HY-P702896

	*AMPK gamma 1/beta 1/alpha 1 Heterotrimer Protein, Human (sf9, His)* AMPK1	Human	Sf9 insect cells
	AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK) and is an important regulator of cellular energy metabolism. It is activated by low ATP levels, enhancing energy production while inhibiting biosynthetic processes and cell growth. AMPK gamma 1/beta 1/alpha 1 Protein, Human (sf9, His) is the recombinant human-derived AMPK gamma 1/beta 1/alpha 1, expressed by Sf9 insect cells, with C-6*His labeled tag.

HY-P704686

	IgG1 Protein, Human (232a.a, HEK293) Ig gamma-1 chain C region; IGHG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (232a.a, HEK293) is the recombinant human-derived IgG1 protein, expressed by HEK293, with tag free.

HY-P705033

	IgG1 Protein, Human (Biotinylated, HEK293, C-Avi) Ig gamma-1 chain C region; IGHG1	Human	HEK293

HY-P70796

	IgG1 Protein, Human (D239E, L241M, HEK293) Ig gamma-1 chain C region; IGHG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (D239E, L241M, HEK293) is the recombinant human-derived IgG1 protein, expressed by HEK293 , with tag free.

HY-P70796A

	IgG1 Protein, Human (D239E, L241E, HEK293) Ig gamma-1 chain C region; IGHG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (D239E, L241E, HEK293) is the recombinant human-derived IgG1 protein, expressed by HEK293 , with tag free.

HY-P704681

	IgG1 Protein, Human (C103S, N180A, HEK293, His) Ig gamma-1 chain C region; IGHG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (C103S, N180A, HEK293, His) is the recombinant human-derived IgG1 protein, expressed by HEK293, with C-His labeled tag.

HY-P704680

	IgG1 Protein, Human (C103S, D239E, L241E, HEK293) Ig gamma-1 chain C region; IGHG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (C103S, D239E, L241E, HEK293) is the recombinant human-derived IgG1 protein, expressed by HEK293, with tag free.

HY-P71806

	Gamma-hemolysin component B Protein, S. aureus (P.pastoris, His) hlgB; SA2209; Gamma-hemolysin component B; H-gamma-1; H-gamma-I	Staphylococcus aureus	P. pastoris
	Gamma-hemolysin component B (HLgB) acts as a toxin, creating cell membrane pores with hemolytic and leukotoxic activities. Furthermore, HLgB promotes AMFR-mediated inflammation by promoting “Lys-27” linked ubiquitination of TAB3, mediating TAK1-TAB3 complex formation, and activating NF-kappa-B signaling. Gamma-hemolysin component B Protein, S. aureus (P.pastoris, His) is the recombinant Staphylococcus aureus-derived Gamma-hemolysin component B protein, expressed by P. pastoris , with N-His labeled tag.

HY-P704682

	IgG1 Protein, Human (C103S, L117A, L118A, HEK293, His) Ig gamma-1 chain C region; IGHG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (C103S, L117A, L118A, HEK293, His) is the recombinant human-derived IgG1 protein, expressed by HEK293, with C-His labeled tag.

HY-P704678

	IgG1 Protein, Human (C103S, L117F, L118E, P214S, HEK293, His) Ig gamma-1 chain C region; IGHG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (C103S, L117F, L118E, P214S, HEK293, His) is the recombinant human-derived IgG1 protein, expressed by HEK293, with C-His labeled tag.

HY-P704683

	IgG1 Protein, Human (C103S, M135Y, S137T, T139E, HEK293, His) Ig gamma-1 chain C region; IGHG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (C103S, M135Y, S137T, T139E, HEK293, His) is the recombinant human-derived IgG1 protein, expressed by HEK293, with C-His labeled tag.

HY-P704679

	IgG1 Protein, Human (C103S, M135Y, S137T, T139E, H316K, N317F, HEK293, His) Ig gamma-1 chain C region; IGHG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. IgG1 Protein, Human (C103S, M135Y, S137T, T139E, H316K, N317F, HEK293, His) is the recombinant human-derived IgG1 protein, expressed by HEK293, with C-His labeled tag.

HY-P704684

	FITC-Labeled IgG1 Protein, Human (C103S, M135Y, S137T, T139E, H316K, N317F, HEK293, His) Ig gamma-1 chain C region; IGHG1	Human	HEK293
	The IgG1 protein is the constant region of the immunoglobulin heavy chain and serves as a receptor during the recognition phase of humoral immunity. It triggers clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. FITC-Labeled IgG1 Protein, Human (C103S, M135Y, S137T, T139E, H316K, N317F, HEK293, His) is the recombinant human-derived FITC-Labeled IgG1 protein, expressed by HEK293, with C-His labeled tag.

HY-P702978

	*AMPK gamma 1/beta 1/alpha 2 Heterotrimer Protein, Human (Inactive, sf9, His)* Subunits A2: PRKAA2; AMPK; AMPK2; PRKAA Subunit B1: PRKAB1; AMPK; HAMPKb; MGC17785 Subunit G1: PRKAG1; AMPKG; MGC866	Human	Sf9 insect cells
	AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK) and is an important regulator of cellular energy metabolism. It is activated by low ATP levels, enhancing energy production while inhibiting biosynthetic processes and cell growth. AMPK (gamma 1/beta 1/alpha 2) Protein, Human (Unactive, sf9, His) is the recombinant human-derived AMPK (gamma 1/beta 1/alpha 2), expressed by Sf9 insect cells, with His labeled tag.

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Source
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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-17386S

Rosiglitazone-d3
Rosiglitazone-d₃ is the deuterium labeled Rosiglitazone. Rosiglitazone (BRL 49653) is a selective, orally active PPARγ agonist with EC₅₀s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively. Rosiglitazone binds to PPARγ with a Kd of approximately 40 nM. Rosiglitazone is also an activator of TRPC5 (EC₅₀=~30 μM) and an inhibitor of TRPM3 ^[1] .

HY-14728S

Deutaleglitazar
Deutaleglitazar (Aleglitazar-d₂) is a agonist of dual peroxisome proliferatory activating receptor (PPARα and PPARγ) .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80543

	*AMPK gamma 1* Antibody (YA621)** AMPKG	WB, ICC/IF, IP	Human
	AMPK gamma 1 Antibody (YA621) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AMPK gamma 1.

HY-P80427

	*Phospholipase C gamma 1* Antibody (YA179)** PLC gamma 1 antibody; PLC II antibody; PLC-148 antibody; PLCgamma1 antibody; PLCG1; NCKAP3	WB, ICC/IF, IP	Human
	Phospholipase C gamma 1 Antibody (YA179) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospholipase C gamma 1.

HY-P87859

	Phospho-PLC γ1 (Tyr783) Antibody (YA7544)	WB, IHC, ICC/IF, IP, ELISA	Human, Mouse, Rat

HY-P85706

	*AMPK gamma 1* Antibody (YA5398)** 5'-AMP-activated protein kinase subunit gamma-1; AMPK gamma1; AMPK subunit gamma-1; AMPKg;	IHC-P, WB	Human, Mouse, Rat
	AMPK gamma 1 Antibody (YA5398) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to AMPK gamma 1.

HY-P88038

	*Laminin gamma 1* Antibody (YA7723)**	WB, FC	Human

HY-P84393

	*AMPK gamma 1* Antibody (YA4090)** AMPKG	IHC-P, ICC/IF, FC, ELISA	Human
	AMPK gamma 1 Antibody (YA4090) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to AMPK gamma 1.

HY-P86178

	*Phospholipase C gamma 1* Antibody (YA5870)** PLCG1; PLC1; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase gamma-1; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Phospholipase C gamma 1 Antibody (YA5870) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospholipase C gamma 1.

HY-P87158

	gamma Adaptin Antibody (YA6851) Adapter-related protein complex 1 subunit gamma-1 antibody; Adaptor protein complex AP 1 gamma 1 subunit antibody; Adaptor protein complex AP 1 subunit gamma 1 antibody; Adaptor protein complex AP-1 subunit gamma-1 antibody; Adaptor related protein complex 1 gamma 1 subunit antibody; ADTG antibody; AP 1 complex subunit gamma 1 antibody; AP-1 complex subunit gamma-1 antibody; AP1G1 antibody; AP1G1_HUMAN antibody; Adapter-related protein complex 1 subunit gamma-1 antibody; Adaptor protein complex AP 1 gamma 1 subunit antibody; Adaptor protein complex AP 1 subunit gamma 1 antibody; Adaptor protein complex AP-1 subunit gamma-1 antibody; Adaptor related protein complex 1 gamma 1 subunit antibody; ADTG antibody; AP 1 complex subunit gamma 1 antibody; AP-1 complex subunit gamma-1 antibody; AP1G1 antibody; AP1G1_HUMAN antibody; CLAPG1 antibody; Clathrin assembly protein complex 1 gamma 1 large chain antibody; Clathrin assembly protein complex 1 gamma large chain antibody; Clathrin assembly protein complex 1 gamma-1 large chain antibody; Clathrin associated/assembly/adaptor protein large gamma 1 antibody; Gamma1 adaptin antibody; Gamma1-adaptin antibody; Golgi adaptor HA1/AP1 adaptin gamma subunit antibody; Golgi adaptor HA1/AP1 adaptin subunit gamma 1 antibody; Golgi adaptor HA1/AP1 adaptin subunit gamma-1 antibody; MGC18255 antibody;	WB, IHC-P	Human, Mouse, Rat
	gamma Adaptin Antibody (YA6851) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to gamma Adaptin.

HY-P84153

	*Phospholipase C gamma 1* Antibody (YA3850)** PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1	WB, IHC-P, ICC/IF, FC, ELISA	Human, Rat, Monkey
	Phospholipase C gamma 1 Antibody (YA3850) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Phospholipase C gamma 1.

HY-P84154

	*Phospholipase C gamma 1* Antibody (YA3851)** PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse
	Phospholipase C gamma 1 Antibody (YA3851) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Phospholipase C gamma 1.

HY-P86739

	Gamma Tubulin Antibody (YA6431) Centrosome Marker; gamma 1 tubulin; gamma tubulin; gamma-tubulin; gamma 2 tubulin; gamma Tubulin 1; gamma Tubulin 2; gamma tubulin complex component 1; GCP 1; GCP-1; GCP1; MGC131994; TUBG; TUBG1; TUBG2; Tubulin gamma 1 chain; Tubulin gamma 2 chain; Xgam; TBG1_HUMAN; TBG2_HUMAN; Tubulin gamma-1 chain; gamma-1-tubulin; gamma-tubulin complex component 1.	WB, IHC-P, IHC-F, IF-Tissue, FC	Human, Mouse, Rat
	Gamma Tubulin Antibody (YA6431) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Gamma Tubulin.

HY-P80684

	gamma Tubulin Antibody (YA419) TUBG1; TUBG; Tubulin gamma-1 chain; Gamma-1-tubulin; Gamma-tubulin complex component 1; GCP-1	WB, ICC/IF, IP	Human, Mouse, Rat, Hamster
	gamma Tubulin Antibody is a non-conjugated and Rabbit origined IgG monoclonal antibody, targeting to gamma Tubulin. It can be used as a loading control antibody.

HY-P81510

	*Laminin gamma 1* Antibody (YA1255)** LAMC1; LAMB2; Laminin subunit gamma-1; Laminin B2 chain; Laminin-1 subunit gamma; Laminin-10 subunit gamma; Laminin-11 subunit gamma; Laminin-2 subunit gamma; Laminin-3 subunit gamma; Laminin-4 subunit gamma; Laminin-6 subunit gamma; Lamini	IHC-P	Human
	Laminin gamma 1 Antibody (YA1255) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Laminin gamma 1.

HY-P82819

	Fetal Hemoglobin Antibody (YA2564) Gamma 1 globin; Gamma 2 globin; Gamma A hemoglobin; Gamma globin; Hb F Agamma; Hb F Ggamma; HBG1; HBG2; HBGA; HBGR	WB	Human
	Fetal Hemoglobin Antibody (YA2564) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fetal Hemoglobin.

HY-P80872

	PPAR gamma Antibody CIMT1; GLM1; NR1C3; Nuclear receptor subfamily 1 group C member 3; Peroxisome proliferator activated nuclear receptor gamma variant 1; Peroxisome proliferator activated receptor gamma 1; Peroxisome Proliferator Activated Receptor gamma; Peroxisome prolife	ICC/IF, WB, IHC-F, IHC-P, ELISA	Human, Mouse, Rat
	PPAR gamma Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to PPAR gamma.

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Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-130463

POPG sodium salt PG(16:0/18:1); 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol)		Phospholipids
POPG sodium salt is a negatively charged phospholipid. POPG sodium salt affects the interactions of membrane proteins with other molecules by changing the charge characteristics of the lipid environment. POPG sodium salt increases the apparent affinity of Gαq and Gβ₁γ₁ for activated *NTS1*. POPG sodium salt can interact with the positive charge of peptides. POPG sodium salt can be used in Parkinson's disease research ^[1] .

HY-W440983

SDPC PC(18:0/22:6); DHA-PC; 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine		Phospholipids
SDPC (DHA-PC) is a new generation of omega-3 lipids, which contains an ester bond linking DHA at the sn-2 position of phospholipid. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine exerts anti-angiogenesis effect through activating PPARγ. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine significantly declines the proliferation, migration, tube formation of human umbilical vein endothelial cells. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine has the potential for anti-tumor angiogenesis research ^[1].

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