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Results for "

p37

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Inhibitory Antibodies

3

Recombinant Proteins

1

Isotope-Labeled Compounds

6

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14805
    Tecovirimat
    1 Publications Verification

    ST-246

    Orthopoxvirus Arenavirus Infection
    Tecovirimat (ST-246) is an orally bioavailable and selective compound against orthopoxviruses including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses. Tecovirimat is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus .
    Tecovirimat
  • HY-14805A
    Tecovirimat monohydrate
    1 Publications Verification

    ST-246 monohydrate

    Orthopoxvirus Arenavirus Infection
    Tecovirimat (ST-246) monohydrate is the monohydrate form of Tecovirimat (HY-14805). Tecovirimat monohydrate is an orally bioavailable and selective compound against orthopoxviruses [including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses]. Tecovirimat monohydrate is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat monohydrate targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat monohydrate exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus. Tecovirimat monohydrate could be used in the study for orthopoxvirus-induced diseases .
    Tecovirimat monohydrate
  • HY-14805S

    ST-246-d4

    Isotope-Labeled Compounds Orthopoxvirus Arenavirus Infection
    Tecovirimat-d4 (ST-246-d4) is a deuterium-labelled Tecovirimat (HY-14805). Tecovirimat is an orally bioavailable and selective compound against orthopoxviruses [including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses]. Tecovirimat is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus. Tecovirimat could be used in the study for orthopoxvirus-induced diseases .
    Tecovirimat-d4
  • HY-178449

    Orthopoxvirus Infection
    Orthopoxviruses-IN-1 (Compound 4) is a potent p37 protein inhibitor (IC50= 0.017 µM against Vaccinia virus (VACV)). Orthopoxviruses-IN-1 is promising for research of orthopoxvirus-related diseases, including variola virus (smallpox) and monkeypox .
    Orthopoxviruses-IN-1
  • HY-172775

    Orthopoxvirus Infection
    Spirovirimat (Compound 7) is a potent Monkeypox virus (MPXV) p37 protein inhibitor with an IC50 value of 35 nM. Spirovirimat blocks the formation of extracellular virions by inhibiting viral membrane wrapping. Spirovirimat is promising for research of Monkeypox virus infections .
    Spirovirimat
  • HY-RS02132

    Small Interfering RNA (siRNA) Others

    CCNH Human Pre-designed siRNA Set A contains three designed siRNAs for CCNH gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CCNH Human Pre-designed siRNA Set A
    CCNH Human Pre-designed siRNA Set A
  • HY-P990852

    Transmembrane Glycoprotein Cancer
    Anti-CEACAM7 Antibody (P3-7B) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CEACAM7. Anti-CEACAM7 Antibody (P3-7B) reacts with human carcinoembryonic antigen-related cell adhesion molecule 7 (CEACAM7). Anti-CEACAM7 Antibody (P3-7B) can be used for detecting CEACAM7 in cancer.
    Anti-CEACAM7 Antibody (P3-7B)
  • HY-RS06267

    Small Interfering RNA (siRNA) Others

    HNRNPD Human Pre-designed siRNA Set A contains three designed siRNAs for HNRNPD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    HNRNPD Human Pre-designed siRNA Set A
    HNRNPD Human Pre-designed siRNA Set A
  • HY-RS02276

    Small Interfering RNA (siRNA) Others

    CD8B Human Pre-designed siRNA Set A contains three designed siRNAs for CD8B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CD8B Human Pre-designed siRNA Set A
    CD8B Human Pre-designed siRNA Set A

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